SIMILAR PATTERNS OF AMINO ACIDS FOR 1MAG_B_DVAB6_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bwu | PROTEIN (AGGLUTININ) (Allium sativum) |
PF01453(B_lectin) | 3 | ALA Q 55VAL Q 64TRP Q 74 | None | 0.93A | 1magB-1bwuQ:undetectable | 1magB-1bwuQ:12.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1edg | ENDOGLUCANASE A ([Clostridium]cellulolyticum) |
PF00150(Cellulase) | 3 | ALA A 41VAL A 82TRP A 99 | None | 0.78A | 1magB-1edgA:undetectable | 1magB-1edgA:3.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h0h | FORMATEDEHYDROGENASESUBUNIT ALPHA (Desulfovibriogigas) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 3 | ALA A 77VAL A 567TRP A 553 | None | 0.89A | 1magB-1h0hA:undetectable | 1magB-1h0hA:1.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hcy | ARTHROPODANHEMOCYANIN (Panulirusinterruptus) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 3 | ALA A 284VAL A 286TRP A 248 | None | 0.84A | 1magB-1hcyA:undetectable | 1magB-1hcyA:2.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k7h | ALKALINE PHOSPHATASE (Pandalusborealis) |
PF00245(Alk_phosphatase) | 3 | ALA A 355VAL A 353TRP A 440 | None | 0.92A | 1magB-1k7hA:undetectable | 1magB-1k7hA:2.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kmq | TRANSFORMING PROTEINRHOA (Homo sapiens) |
PF00071(Ras) | 3 | ALA A 61VAL A 11TRP A 99 | None | 0.93A | 1magB-1kmqA:undetectable | 1magB-1kmqA:6.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kqf | FORMATEDEHYDROGENASE,NITRATE-INDUCIBLE,MAJOR SUBUNIT (Escherichiacoli) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 3 | ALA A 115VAL A 611TRP A 593 | None | 0.92A | 1magB-1kqfA:undetectable | 1magB-1kqfA:2.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mu2 | HIV-2 RT (Humanimmunodeficiencyvirus 2) |
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb) | 3 | ALA A 368VAL A 370TRP A 337 | None | 0.95A | 1magB-1mu2A:undetectable | 1magB-1mu2A:4.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r6v | SUBTILISIN-LIKESERINE PROTEASE (Fervidobacteriumpennivorans) |
PF00082(Peptidase_S8) | 3 | ALA A 218VAL A 228TRP A 156 | None | 0.94A | 1magB-1r6vA:undetectable | 1magB-1r6vA:6.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rbl | RIBULOSE 1,5BISPHOSPHATECARBOXYLASE/OXYGENASE (LARGE CHAIN) (Synechococcuselongatus) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 3 | ALA A 15VAL A 17TRP A 66 | None | 0.92A | 1magB-1rblA:undetectable | 1magB-1rblA:4.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rfo | WHISKER ANTIGENCONTROL PROTEIN (Escherichiavirus T4) |
PF07921(Fibritin_C) | 3 | ALA A 12VAL A 21TRP A 20 | None | 0.87A | 1magB-1rfoA:undetectable | 1magB-1rfoA:18.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sfr | ANTIGEN 85-A (Mycobacteriumtuberculosis) |
PF00756(Esterase) | 3 | ALA A 129VAL A 123TRP A 51 | None | 0.90A | 1magB-1sfrA:undetectable | 1magB-1sfrA:6.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ta3 | ENDO-1,4-BETA-XYLANASE (Aspergillusnidulans) |
PF00331(Glyco_hydro_10) | 3 | ALA B 183VAL B 188TRP B 191 | None | 0.95A | 1magB-1ta3B:undetectable | 1magB-1ta3B:4.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tkc | TRANSKETOLASE (Saccharomycescerevisiae) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 3 | ALA A 423VAL A 453TRP A 465 | None | 0.89A | 1magB-1tkcA:undetectable | 1magB-1tkcA:1.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wom | SIGMA FACTOR SIGBREGULATION PROTEINRSBQ (Bacillussubtilis) |
PF12697(Abhydrolase_6) | 3 | ALA A 36VAL A 33TRP A 34 | PGO A 604 ( 3.9A)PGO A 604 (-4.8A)None | 0.92A | 1magB-1womA:undetectable | 1magB-1womA:18.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z72 | TRANSCRIPTIONALREGULATOR, PUTATIVE (Streptococcuspneumoniae) |
PF03070(TENA_THI-4) | 3 | ALA A 145VAL A 209TRP A 25 | ACY A 801 ( 4.6A)NoneNone | 0.92A | 1magB-1z72A:undetectable | 1magB-1z72A:7.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2atx | SMALL GTP BINDINGPROTEIN TC10 (Homo sapiens) |
PF00071(Ras) | 3 | ALA A 73VAL A 23TRP A 111 | GNP A 200 ( 4.4A)NoneNone | 0.91A | 1magB-2atxA:undetectable | 1magB-2atxA:5.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c4m | GLYCOGENPHOSPHORYLASE (Corynebacteriumcallunae) |
PF00343(Phosphorylase) | 3 | ALA A 402VAL A 325TRP A 322 | None | 0.90A | 1magB-2c4mA:undetectable | 1magB-2c4mA:3.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ciy | CHLOROPEROXIDASE (Leptoxyphiumfumago) |
PF01328(Peroxidase_2) | 3 | ALA A 189VAL A 191TRP A 213 | None | 0.92A | 1magB-2ciyA:undetectable | 1magB-2ciyA:6.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gen | PROBABLETRANSCRIPTIONALREGULATOR (Pseudomonasaeruginosa) |
PF00440(TetR_N) | 3 | ALA A 192VAL A 190TRP A 187 | None | 0.67A | 1magB-2genA:undetectable | 1magB-2genA:8.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gup | ROK FAMILY PROTEIN (Streptococcuspneumoniae) |
PF00480(ROK) | 3 | ALA A 204VAL A 173TRP A 185 | None | 0.96A | 1magB-2gupA:undetectable | 1magB-2gupA:5.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i44 | SERINE-THREONINEPHOSPHATASE 2C (Toxoplasmagondii) |
PF00481(PP2C) | 3 | ALA A 61VAL A 54TRP A 92 | None | 0.90A | 1magB-2i44A:undetectable | 1magB-2i44A:4.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2in3 | HYPOTHETICAL PROTEIN (Nitrosomonaseuropaea) |
PF01323(DSBA) | 3 | ALA A 119VAL A 122TRP A 20 | None | 0.76A | 1magB-2in3A:undetectable | 1magB-2in3A:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jep | XYLOGLUCANASE (Paenibacilluspabuli) |
PF00150(Cellulase) | 3 | ALA A 54VAL A 90TRP A 108 | None | 0.73A | 1magB-2jepA:undetectable | 1magB-2jepA:5.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jgp | TYROCIDINESYNTHETASE 3 (Brevibacillusbrevis) |
PF00550(PP-binding)PF00668(Condensation) | 3 | ALA A 32VAL A 30TRP A 21 | None | 0.78A | 1magB-2jgpA:undetectable | 1magB-2jgpA:5.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mgy | TRANSLOCATOR PROTEIN (Mus musculus) |
PF03073(TspO_MBR) | 3 | ALA A 110VAL A 115TRP A 143 | PKA A 201 (-2.9A)NoneNone | 0.92A | 1magB-2mgyA:undetectable | 1magB-2mgyA:8.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2okq | HYPOTHETICAL PROTEINYBAA (Shigellaflexneri) |
PF07237(DUF1428) | 3 | ALA A 10VAL A 67TRP A 42 | None | 0.88A | 1magB-2okqA:undetectable | 1magB-2okqA:6.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pgg | RNA-DIRECTED RNAPOLYMERASE (Infectiousbursal diseasevirus) |
PF04197(Birna_RdRp) | 3 | ALA A 397VAL A 407TRP A 412 | None | 0.91A | 1magB-2pggA:undetectable | 1magB-2pggA:2.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q3h | RAS HOMOLOG GENEFAMILY, MEMBER U (Homo sapiens) |
PF00071(Ras) | 3 | ALA A 105VAL A 55TRP A 143 | None | 0.92A | 1magB-2q3hA:undetectable | 1magB-2q3hA:12.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v72 | EXO-ALPHA-SIALIDASE (Clostridiumperfringens) |
PF00754(F5_F8_type_C) | 3 | ALA A 64VAL A 106TRP A 97 | None | 0.74A | 1magB-2v72A:undetectable | 1magB-2v72A:4.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wkp | NPH1-1, RAS-RELATEDC3 BOTULINUM TOXINSUBSTRATE 1 (Avena sativa;Homo sapiens) |
PF00071(Ras)PF13426(PAS_9) | 3 | ALA A 602VAL A 552TRP A 640 | None | 0.93A | 1magB-2wkpA:undetectable | 1magB-2wkpA:4.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z2x | TK-SUBTILISIN (Thermococcuskodakarensis) |
PF00082(Peptidase_S8) | 3 | ALA A 163VAL A 173TRP A 99 | None | 0.92A | 1magB-2z2xA:undetectable | 1magB-2z2xA:7.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z2z | TK-SUBTILISINPRECURSOR (Thermococcuskodakarensis) |
PF00082(Peptidase_S8) | 3 | ALA A 163VAL A 173TRP A 99 | None | 0.91A | 1magB-2z2zA:undetectable | 1magB-2z2zA:13.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3azq | AMINOPEPTIDASE (Streptomycesmorookaense) |
PF00326(Peptidase_S9) | 3 | ALA A 308VAL A 310TRP A 338 | None | 0.91A | 1magB-3azqA:undetectable | 1magB-3azqA:2.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e3a | POSSIBLE PEROXIDASEBPOC (Mycobacteriumtuberculosis) |
PF12697(Abhydrolase_6) | 3 | ALA A 90VAL A 84TRP A 28 | None | 0.92A | 1magB-3e3aA:undetectable | 1magB-3e3aA:7.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fqd | 5'-3'EXORIBONUCLEASE 2 (Schizosaccharomycespombe) |
PF03159(XRN_N) | 3 | ALA A 81VAL A 60TRP A 157 | None | 0.88A | 1magB-3fqdA:undetectable | 1magB-3fqdA:2.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ju1 | ENOYL-COAHYDRATASE/ISOMERASEFAMILY PROTEIN (Shewanellaoneidensis) |
PF16113(ECH_2) | 3 | ALA A 355VAL A 357TRP A 300 | None | 0.93A | 1magB-3ju1A:undetectable | 1magB-3ju1A:5.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m49 | TRANSKETOLASE (Bacillusanthracis) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 3 | ALA A 367VAL A 372TRP A 342 | GOL A 705 ( 3.8A)NoneNone | 0.72A | 1magB-3m49A:undetectable | 1magB-3m49A:1.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ndy | ENDOGLUCANASE D (Clostridiumcellulovorans) |
PF00150(Cellulase) | 3 | ALA A 34VAL A 66TRP A 84 | None | 0.83A | 1magB-3ndyA:undetectable | 1magB-3ndyA:7.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p3l | CYTOCHROME P450 (Streptomycesthioluteus) |
PF00067(p450) | 3 | ALA A 319VAL A 321TRP A 26 | None | 0.93A | 1magB-3p3lA:undetectable | 1magB-3p3lA:3.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qld | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Alicyclobacillusacidocaldarius) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | ALA A 353VAL A 355TRP A 358 | None | 0.95A | 1magB-3qldA:undetectable | 1magB-3qldA:3.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ryt | RAS-RELATED C3BOTULINUM TOXINSUBSTRATE 1 (Homo sapiens) |
PF00071(Ras) | 3 | ALA C 59VAL C 9TRP C 97 | None | 0.90A | 1magB-3rytC:undetectable | 1magB-3rytC:12.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sz3 | TRYPTOPHANYL-TRNASYNTHETASE (Vibrio cholerae) |
PF00579(tRNA-synt_1b) | 3 | ALA A 69VAL A 72TRP A 28 | None | 0.77A | 1magB-3sz3A:undetectable | 1magB-3sz3A:7.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3trp | CALSEQUESTRIN-1 (Oryctolaguscuniculus) |
PF01216(Calsequestrin) | 3 | ALA A 320VAL A 317TRP A 242 | MRD A 355 ( 3.9A)NoneMRD A 355 (-4.0A) | 0.96A | 1magB-3trpA:undetectable | 1magB-3trpA:3.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3usc | HYDROGENASE-1 LARGECHAIN (Escherichiacoli) |
PF00374(NiFeSe_Hases) | 3 | ALA L 86VAL L 88TRP L 232 | None | 0.89A | 1magB-3uscL:undetectable | 1magB-3uscL:5.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v48 | PUTATIVEAMINOACRYLATEHYDROLASE RUTD (Escherichiacoli) |
PF00561(Abhydrolase_1) | 3 | ALA A 91VAL A 85TRP A 29 | None | 0.96A | 1magB-3v48A:undetectable | 1magB-3v48A:6.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wyf | GSP1P (Saccharomycescerevisiae) |
PF00071(Ras) | 3 | ALA A 69VAL A 18TRP A 106 | GTP A 301 ( 4.9A)NoneNone | 0.87A | 1magB-3wyfA:undetectable | 1magB-3wyfA:6.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zmr | CELLULASE (GLYCOSYLHYDROLASE FAMILY 5) (Bacteroidesovatus) |
PF00150(Cellulase)PF13004(BACON) | 3 | ALA A 169VAL A 210TRP A 228 | None | 0.63A | 1magB-3zmrA:undetectable | 1magB-3zmrA:2.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bmv | SHORT-CHAINDEHYDROGENASE (Sphingobiumyanoikuyae) |
PF00106(adh_short) | 3 | ALA A 184VAL A 204TRP A 191 | NoneNoneNAP A 300 (-4.0A) | 0.88A | 1magB-4bmvA:undetectable | 1magB-4bmvA:8.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dvg | RHO-LIKE SMALLGTPASE (Entamoebahistolytica) |
PF00071(Ras) | 3 | ALA A 76VAL A 26TRP A 114 | None | 0.90A | 1magB-4dvgA:undetectable | 1magB-4dvgA:9.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4giw | RUN AND SH3DOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF02759(RUN) | 3 | ALA A 89VAL A 91TRP A 136 | None | 0.91A | 1magB-4giwA:undetectable | 1magB-4giwA:7.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4im4 | ENDOGLUCANASE E (Ruminiclostridiumthermocellum) |
PF00150(Cellulase) | 3 | ALA A 76VAL A 107TRP A 125 | None | 0.87A | 1magB-4im4A:undetectable | 1magB-4im4A:7.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j0k | TANNASE (Lactobacillusplantarum) |
no annotation | 3 | ALA A 172VAL A 407TRP A 411 | None | 0.94A | 1magB-4j0kA:undetectable | 1magB-4j0kA:3.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k6m | POLYPROTEIN (Japaneseencephalitisvirus) |
PF00972(Flavi_NS5)PF01728(FtsJ) | 3 | ALA A 628VAL A 631TRP A 651 | None | 0.89A | 1magB-4k6mA:undetectable | 1magB-4k6mA:1.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lmh | EXTRACELLULAR IRONOXIDE RESPIRATORYSYSTEM SURFACEDECAHEME CYTOCHROMEC COMPONENT OMCA (Shewanellaoneidensis) |
no annotation | 3 | ALA A 710VAL A 712TRP A 673 | None | 0.91A | 1magB-4lmhA:undetectable | 1magB-4lmhA:2.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mit | RHO FAMILY GTPASE (Entamoebahistolytica) |
PF00071(Ras) | 3 | ALA A 66VAL A 16TRP A 104 | None | 0.88A | 1magB-4mitA:undetectable | 1magB-4mitA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mkv | RIBULOSEBISPHOSPHATECARBOXYLASE LARGECHAIN (Pisum sativum) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 3 | ALA A 15VAL A 17TRP A 66 | None | 0.79A | 1magB-4mkvA:undetectable | 1magB-4mkvA:3.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mtp | RNA DEPENDENT RNAPOLYMERASE (Japaneseencephalitisvirus) |
PF00972(Flavi_NS5) | 3 | ALA A 628VAL A 631TRP A 651 | ALA A 628 ( 0.0A)VAL A 631 ( 0.6A)TRP A 651 ( 0.5A) | 0.83A | 1magB-4mtpA:undetectable | 1magB-4mtpA:2.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n9w | GDP-MANNOSE-DEPENDENTALPHA-(1-2)-PHOSPHATIDYLINOSITOLMANNOSYLTRANSFERASE (Mycolicibacteriumsmegmatis) |
PF13439(Glyco_transf_4)PF13692(Glyco_trans_1_4) | 3 | ALA A 25VAL A 27TRP A 349 | None | 0.89A | 1magB-4n9wA:undetectable | 1magB-4n9wA:6.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p1c | TOLUENE-4-MONOOXYGENASE SYSTEM PROTEIN A (Pseudomonasmendocina) |
PF02332(Phenol_Hydrox) | 3 | ALA A 489VAL A 350TRP A 336 | None | 0.89A | 1magB-4p1cA:undetectable | 1magB-4p1cA:4.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pob | THIOREDOXIN (Mycobacteroidesabscessus) |
PF00085(Thioredoxin) | 3 | ALA A 64VAL A 62TRP A 30 | None | 0.88A | 1magB-4pobA:undetectable | 1magB-4pobA:29.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qgl | ACIREDUCTONEDIOXYGENASE (Bacillusanthracis) |
PF03079(ARD) | 3 | ALA A 65VAL A 67TRP A 33 | None | 0.96A | 1magB-4qglA:undetectable | 1magB-4qglA:5.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rgq | GLYCEROL-1-PHOSPHATEDEHYDROGENASE (Methanocaldococcusjannaschii) |
PF13685(Fe-ADH_2) | 3 | ALA A 221VAL A 156TRP A 159 | K A 402 ( 3.6A)NoneNone | 0.75A | 1magB-4rgqA:undetectable | 1magB-4rgqA:3.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u5x | RAC-LIKE GTP-BINDINGPROTEIN 1 (Oryza sativa) |
PF00071(Ras) | 3 | ALA A 66VAL A 16TRP A 104 | GNP A 201 ( 4.5A)NoneNone | 0.90A | 1magB-4u5xA:undetectable | 1magB-4u5xA:12.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w87 | XYLOGLUCAN-SPECIFICENDO-BETA-1,4-GLUCANASE (unculturedbacterium) |
PF00150(Cellulase) | 3 | ALA A 115VAL A 153TRP A 171 | None | 0.68A | 1magB-4w87A:undetectable | 1magB-4w87A:9.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xxp | PUTATIVEUNCHARACTERIZEDPROTEIN (RV0315ORTHOLOG) (Mycobacteriumavium) |
PF00722(Glyco_hydro_16) | 3 | ALA A 174VAL A 162TRP A 200 | None | 0.94A | 1magB-4xxpA:undetectable | 1magB-4xxpA:7.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yhg | GH5 (Bacteroidetesbacterium AC2a) |
PF00150(Cellulase) | 3 | ALA A 34VAL A 70TRP A 88 | None | 0.93A | 1magB-4yhgA:undetectable | 1magB-4yhgA:7.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yzt | CELLULOSE HYDROLASE (Bacilluslicheniformis) |
PF00150(Cellulase)PF03442(CBM_X2) | 3 | ALA A 40VAL A 72TRP A 90 | None | 0.75A | 1magB-4yztA:undetectable | 1magB-4yztA:2.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b4x | LOW DENSITYLIPOPROTEINRECEPTOR-RELATEDPROTEIN 8,APOLIPOPROTEIN ERECEPTOR, ISOFORMCRA_E (Homo sapiens) |
PF00057(Ldl_recept_a)PF00058(Ldl_recept_b)PF07645(EGF_CA)PF14670(FXa_inhibition) | 3 | ALA B 433VAL B 449TRP B 470 | None | 0.80A | 1magB-5b4xB:undetectable | 1magB-5b4xB:2.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d9n | B-1,4-ENDOGLUCANASE (Prevotellabryantii) |
PF00150(Cellulase) | 3 | ALA A 32VAL A 73TRP A 89 | None | 0.78A | 1magB-5d9nA:undetectable | 1magB-5d9nA:3.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dac | PUTATIVEUNCHARACTERIZEDPROTEIN,PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
PF13476(AAA_23) | 3 | ALA A 149VAL A 154TRP A 164 | None | 0.95A | 1magB-5dacA:undetectable | 1magB-5dacA:3.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dis | GTP-BINDING NUCLEARPROTEIN RAN (Homo sapiens) |
PF00071(Ras) | 3 | ALA B 67VAL B 16TRP B 104 | GTP B 201 ( 4.6A)NoneNone | 0.89A | 1magB-5disB:undetectable | 1magB-5disB:7.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e7l | CONTACTIN-2 (Mus musculus) |
PF00041(fn3) | 3 | ALA A 819VAL A 821TRP A 822 | None | 0.94A | 1magB-5e7lA:undetectable | 1magB-5e7lA:10.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g5n | LH3HEXON-INTERLACINGCAPSID PROTEIN (Snakeatadenovirus A) |
PF01696(Adeno_E1B_55K) | 3 | ALA A 180VAL A 204TRP A 209 | None | 0.94A | 1magB-5g5nA:undetectable | 1magB-5g5nA:5.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ghe | PESTICIDAL CRYSTALPROTEIN CRY6AA (Bacillusthuringiensis) |
no annotation | 3 | ALA A 113VAL A 373TRP A 370 | None | 0.85A | 1magB-5gheA:undetectable | 1magB-5gheA:2.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gnx | BETA-GLUCOSIDASE (metagenome) |
PF00232(Glyco_hydro_1) | 3 | ALA A 198VAL A 196TRP A 253 | None | 0.92A | 1magB-5gnxA:undetectable | 1magB-5gnxA:4.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h0u | MATRIXMETALLOPROTEINASE-14 (Homo sapiens) |
PF00413(Peptidase_M10) | 3 | ALA A 154VAL A 150TRP A 151 | None | 0.93A | 1magB-5h0uA:undetectable | 1magB-5h0uA:8.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h4r | BETA-1,3-1,4-GLUCANASE (Caldicellulosiruptorsp. F32) |
PF00150(Cellulase) | 3 | ALA A 59VAL A 101TRP A 118 | None | 0.75A | 1magB-5h4rA:undetectable | 1magB-5h4rA:3.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h98 | GEOBACTERMETALLIREDUCENSSMUG1 (Geobactermetallireducens) |
no annotation | 3 | ALA A 135VAL A 69TRP A 115 | None | 0.82A | 1magB-5h98A:undetectable | 1magB-5h98A:9.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hzh | RAS-RELATED C3BOTULINUM TOXINSUBSTRATE1,NPH1-1,RAS-RELATEDC3 BOTULINUM TOXINSUBSTRATE 1 (Avena sativa;Homo sapiens) |
PF00071(Ras)PF13426(PAS_9) | 3 | ALA A 208VAL A 9TRP A 246 | None | 0.92A | 1magB-5hzhA:undetectable | 1magB-5hzhA:6.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i51 | TRANSKETOLASE (Scheffersomycesstipitis) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 3 | ALA A 420VAL A 450TRP A 462 | None | 0.90A | 1magB-5i51A:undetectable | 1magB-5i51A:1.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jcp | ARF-GAP WITH RHO-GAPDOMAIN, ANK REPEATAND PHDOMAIN-CONTAININGPROTEIN3,LINKER,TRANSFORMING PROTEIN RHOA (Homo sapiens;syntheticconstruct) |
no annotation | 3 | ALA B 61VAL B 11TRP B 99 | ALF B1203 ( 4.7A)NoneNone | 0.91A | 1magB-5jcpB:undetectable | 1magB-5jcpB:3.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kdx | METALLOPEPTIDASE (Pseudomonasaeruginosa) |
PF13402(Peptidase_M60) | 3 | ALA A 670VAL A 666TRP A 685 | None | 0.80A | 1magB-5kdxA:undetectable | 1magB-5kdxA:3.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kuc | PESTICIDAL CRYSTALPROTEIN CRY6AA (Bacillusthuringiensis) |
no annotation | 3 | ALA A 113VAL A 373TRP A 370 | None | 0.87A | 1magB-5kucA:undetectable | 1magB-5kucA:2.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nf4 | MINOR FIMBRIUM TIPSUBUNIT MFA3 (Porphyromonasgingivalis) |
no annotation | 3 | ALA A 240VAL A 238TRP A 244 | None | 0.92A | 1magB-5nf4A:undetectable | 1magB-5nf4A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nmp | ISATIN HYDROLASE (Ralstoniasolanacearum) |
no annotation | 3 | ALA A 115VAL A 117TRP A 123 | None | 0.95A | 1magB-5nmpA:undetectable | 1magB-5nmpA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nv3 | RIBULOSEBISPHOSPHATECARBOXYLASE LARGECHAIN (Rhodobactersphaeroides) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 3 | ALA A 16VAL A 18TRP A 68 | None | 0.90A | 1magB-5nv3A:undetectable | 1magB-5nv3A:3.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oms | CYTOCHROME P450 (Amycolatopsissp. ATCC 39116) |
no annotation | 3 | ALA A 297VAL A 47TRP A 393 | None | 0.94A | 1magB-5omsA:undetectable | 1magB-5omsA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oyd | CELLULASE, PUTATIVE,CEL5D (Cellvibriojaponicus) |
no annotation | 3 | ALA A 136VAL A 168TRP A 185 | None | 0.60A | 1magB-5oydA:undetectable | 1magB-5oydA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v2m | MEVALONATEDIPHOSPHATEDECARBOXYLASE (Enterococcusfaecalis) |
no annotation | 3 | ALA A 249VAL A 199TRP A 18 | None | 0.77A | 1magB-5v2mA:undetectable | 1magB-5v2mA:4.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vgs | LACHRYMATORY-FACTORSYNTHASE (Allium cepa) |
PF10604(Polyketide_cyc2) | 3 | ALA A 27VAL A 25TRP A 133 | NoneNone9A7 A 202 (-3.4A) | 0.94A | 1magB-5vgsA:undetectable | 1magB-5vgsA:8.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wsl | KERATINASE (Meiothermustaiwanensis) |
no annotation | 3 | ALA A 55VAL A 96TRP A 116 | None | 0.87A | 1magB-5wslA:undetectable | 1magB-5wslA:5.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xd0 | GLUCANASE (Paenibacillussp. X4) |
PF01270(Glyco_hydro_8) | 3 | ALA A 241VAL A 243TRP A 201 | None | 0.94A | 1magB-5xd0A:undetectable | 1magB-5xd0A:2.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zgb | LHCR3 (Cyanidioschyzonmerolae) |
no annotation | 3 | ALA 3 114VAL 3 119TRP 3 47 | NoneNoneCLA 3 208 (-3.4A) | 0.92A | 1magB-5zgb3:undetectable | 1magB-5zgb3:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zvs | PUTATIVE COREPROTEIN NTPASE/VP5 (Aquareovirus C) |
no annotation | 3 | ALA 4 243VAL 4 248TRP 4 257 | None | 0.80A | 1magB-5zvs4:undetectable | 1magB-5zvs4:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6avw | CARBOXYLESTERASESOBER1 (Arabidopsisthaliana) |
no annotation | 3 | ALA A 63VAL A 163TRP A 132 | None | 0.94A | 1magB-6avwA:undetectable | 1magB-6avwA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f9m | SERINE PROTEASE (Planococcusplakortidis) |
no annotation | 3 | ALA A 96VAL A 107TRP A 34 | NA A 402 ( 4.7A)NoneNone | 0.94A | 1magB-6f9mA:undetectable | 1magB-6f9mA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fhs | INO80 (Chaetomiumthermophilum) |
no annotation | 3 | ALA G1420VAL G1418TRP G1415 | None | 0.94A | 1magB-6fhsG:undetectable | 1magB-6fhsG:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fml | INO80 (Chaetomiumthermophilum) |
no annotation | 3 | ALA G1420VAL G1418TRP G1415 | None | 0.95A | 1magB-6fmlG:undetectable | 1magB-6fmlG:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6req | PROTEIN(METHYLMALONYL-COAMUTASE) (Propionibacteriumfreudenreichii) |
PF01642(MM_CoA_mutase) | 3 | ALA B 538VAL B 534TRP B 535 | None | 0.81A | 1magB-6reqB:undetectable | 1magB-6reqB:4.88 |