SIMILAR PATTERNS OF AMINO ACIDS FOR 1M00_B_H4BB1760
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c4k | PROTEIN (ORNITHINEDECARBOXYLASE) (Lactobacillussp. 30A) |
PF01276(OKR_DC_1)PF03709(OKR_DC_1_N)PF03711(OKR_DC_1_C) | 4 | TRP A 673PHE A 681GLU A 649VAL A 667 | None | 1.31A | 1m00A-1c4kA:0.01m00B-1c4kA:0.0 | 1m00A-1c4kA:19.231m00B-1c4kA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cyo | CYTOCHROME B5 (Bos taurus) |
PF00173(Cyt-b5) | 4 | PHE A 58GLU A 56ARG A 68VAL A 61 | HEM A 201 (-4.8A)NoneNoneNone | 1.35A | 1m00A-1cyoA:0.01m00B-1cyoA:0.0 | 1m00A-1cyoA:12.111m00B-1cyoA:12.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fhu | O-SUCCINYLBENZOATESYNTHASE (Escherichiacoli) |
PF13378(MR_MLE_C) | 4 | TRP A 66GLU A 76ARG A 2VAL A 87 | None | 1.48A | 1m00A-1fhuA:0.01m00B-1fhuA:0.0 | 1m00A-1fhuA:25.351m00B-1fhuA:25.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1flg | PROTEIN(QUINOPROTEINETHANOLDEHYDROGENASE) (Pseudomonasaeruginosa) |
PF01011(PQQ)PF13360(PQQ_2) | 4 | PHE A 501GLU A 519VAL A 41TRP A 521 | None | 1.28A | 1m00A-1flgA:0.01m00B-1flgA:0.0 | 1m00A-1flgA:21.001m00B-1flgA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h3j | PEROXIDASE (Coprinopsiscinerea) |
PF00141(peroxidase)PF11895(Peroxidase_ext) | 4 | TRP A 258PHE A 211MET A 268VAL A 177 | NoneHSO A 183 ( 3.5A)NoneNone | 1.25A | 1m00A-1h3jA:0.01m00B-1h3jA:0.0 | 1m00A-1h3jA:22.141m00B-1h3jA:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kex | NEUROPILIN-1 (Homo sapiens) |
PF00754(F5_F8_type_C) | 4 | TRP A 97PHE A 131GLU A 95ARG A 130 | None | 1.43A | 1m00A-1kexA:0.01m00B-1kexA:0.0 | 1m00A-1kexA:16.831m00B-1kexA:16.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kh2 | ARGININOSUCCINATESYNTHETASE (Thermusthermophilus) |
PF00764(Arginosuc_synth) | 4 | PHE A 220GLU A 222ARG A 282VAL A 226 | None | 1.33A | 1m00A-1kh2A:0.11m00B-1kh2A:0.0 | 1m00A-1kh2A:22.911m00B-1kh2A:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l5j | ACONITATE HYDRATASE2 (Escherichiacoli) |
PF00330(Aconitase)PF06434(Aconitase_2_N)PF11791(Aconitase_B_N) | 4 | TRP A 155PHE A 156GLU A 154ARG A 340 | None | 1.37A | 1m00A-1l5jA:0.01m00B-1l5jA:0.0 | 1m00A-1l5jA:19.111m00B-1l5jA:19.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lzx | NITRIC-OXIDESYNTHASE (Rattusnorvegicus) |
PF02898(NO_synthase) | 4 | MET A 336ARG A 596VAL A 677TRP A 678 | H4B A 760 ( 3.8A)H4B A 760 (-3.5A)H4B A 760 (-4.6A)H4B A 760 ( 3.6A) | 0.44A | 1m00A-1lzxA:63.71m00B-1lzxA:62.7 | 1m00A-1lzxA:100.001m00B-1lzxA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mhz | METHANEMONOOXYGENASEHYDROXYLASE (Methylosinustrichosporium) |
PF02332(Phenol_Hydrox) | 4 | PHE D 35GLU D 132VAL D 28TRP D 31 | None | 1.33A | 1m00A-1mhzD:undetectable1m00B-1mhzD:undetectable | 1m00A-1mhzD:20.891m00B-1mhzD:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mzb | FERRIC UPTAKEREGULATION PROTEIN (Pseudomonasaeruginosa) |
PF01475(FUR) | 4 | PHE A 79GLU A 36ARG A 69VAL A 54 | None | 1.02A | 1m00A-1mzbA:undetectable1m00B-1mzbA:undetectable | 1m00A-1mzbA:16.711m00B-1mzbA:16.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pdu | NUCLEAR HORMONERECEPTOR HR38 (Drosophilamelanogaster) |
PF00104(Hormone_recep) | 4 | TRP A 435PHE A 432MET A 440VAL A 401 | None | 1.02A | 1m00A-1pduA:undetectable1m00B-1pduA:undetectable | 1m00A-1pduA:19.391m00B-1pduA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t1j | HYPOTHETICAL PROTEIN (Pseudomonasaeruginosa) |
PF09152(DUF1937) | 4 | TRP A 110PHE A 117ARG A 2VAL A 28 | None | 1.49A | 1m00A-1t1jA:undetectable1m00B-1t1jA:undetectable | 1m00A-1t1jA:16.921m00B-1t1jA:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vmk | PURINE NUCLEOSIDEPHOSPHORYLASE (Thermotogamaritima) |
PF01048(PNP_UDP_1) | 4 | TRP A 162PHE A 265GLU A 161VAL A 221 | None | 1.44A | 1m00A-1vmkA:undetectable1m00B-1vmkA:undetectable | 1m00A-1vmkA:21.531m00B-1vmkA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wf0 | TAR DNA-BINDINGPROTEIN-43 (Homo sapiens) |
PF00076(RRM_1) | 4 | PHE A 26GLU A 21MET A 17VAL A 35 | None | 1.12A | 1m00A-1wf0A:undetectable1m00B-1wf0A:undetectable | 1m00A-1wf0A:11.691m00B-1wf0A:11.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wql | ETHYLBENZENEDIOXYGENASE SMALLSUBUNIT (Pseudomonasfluorescens) |
PF00866(Ring_hydroxyl_B) | 4 | PHE B 163GLU B 26ARG B 156VAL B 128 | None | 1.15A | 1m00A-1wqlB:undetectable1m00B-1wqlB:undetectable | 1m00A-1wqlB:19.791m00B-1wqlB:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b39 | C3 (Bos taurus) |
PF00207(A2M)PF01759(NTR)PF01821(ANATO)PF01835(A2M_N)PF07677(A2M_recep)PF07678(A2M_comp)PF07703(A2M_N_2)PF10569(Thiol-ester_cl) | 4 | PHE A 722GLU A 693ARG A 708VAL A1424 | None | 1.08A | 1m00A-2b39A:undetectable1m00B-2b39A:undetectable | 1m00A-2b39A:13.471m00B-2b39A:13.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b4x | ANTITHROMBIN-III (Homo sapiens) |
PF00079(Serpin) | 4 | TRP I 225PHE I 274GLU I 378VAL I 375 | None | 1.49A | 1m00A-2b4xI:undetectable1m00B-2b4xI:undetectable | 1m00A-2b4xI:21.581m00B-2b4xI:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fja | ADENYLYLSULFATEREDUCTASE, SUBUNIT AADENYLYLSULFATEREDUCTASE, SUBUNIT B (Archaeoglobusfulgidus) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C)PF12139(APS-reductase_C)PF13187(Fer4_9) | 4 | TRP B 788GLU A 360ARG A 62VAL A 367 | None | 1.37A | 1m00A-2fjaB:undetectable1m00B-2fjaB:undetectable | 1m00A-2fjaB:18.141m00B-2fjaB:18.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rik | TITIN (Oryctolaguscuniculus) |
PF07679(I-set) | 4 | PHE A 97GLU A 116VAL A 127TRP A 129 | None | 1.49A | 1m00A-2rikA:undetectable1m00B-2rikA:undetectable | 1m00A-2rikA:22.151m00B-2rikA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vda | TRANSLOCASE SUBUNITSECA (Escherichiacoli) |
PF01043(SecA_PP_bind)PF07516(SecA_SW)PF07517(SecA_DEAD) | 4 | GLU A 34MET A 31ARG A 53VAL A 70 | None | 1.49A | 1m00A-2vdaA:undetectable1m00B-2vdaA:undetectable | 1m00A-2vdaA:18.681m00B-2vdaA:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vy0 | ENDO-BETA-1,3-GLUCANASE (Pyrococcusfuriosus) |
PF00722(Glyco_hydro_16) | 4 | TRP A 252PHE A 254GLU A 251VAL A 245 | NoneNoneMRD A1301 (-4.3A)None | 1.44A | 1m00A-2vy0A:undetectable1m00B-2vy0A:undetectable | 1m00A-2vy0A:19.681m00B-2vy0A:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w4o | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE TYPE IV (Homo sapiens) |
PF00069(Pkinase) | 4 | TRP A 266PHE A 261ARG A 278VAL A 269 | None | 1.44A | 1m00A-2w4oA:undetectable1m00B-2w4oA:undetectable | 1m00A-2w4oA:20.911m00B-2w4oA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xhy | 6-PHOSPHO-BETA-GLUCOSIDASE BGLA (Escherichiacoli) |
PF00232(Glyco_hydro_1) | 4 | PHE A 98GLU A 108ARG A 159VAL A 164 | None | 1.46A | 1m00A-2xhyA:0.01m00B-2xhyA:undetectable | 1m00A-2xhyA:20.361m00B-2xhyA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xvg | ALPHA XYLOSIDASE (Cellvibriojaponicus) |
PF01055(Glyco_hydro_31)PF16338(DUF4968)PF17137(DUF5110) | 4 | PHE A 698GLU A 722ARG A 697VAL A 717 | None | 1.31A | 1m00A-2xvgA:0.51m00B-2xvgA:undetectable | 1m00A-2xvgA:19.941m00B-2xvgA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ywb | GMP SYNTHASE[GLUTAMINE-HYDROLYZING] (Thermusthermophilus) |
PF00117(GATase)PF00958(GMP_synt_C) | 4 | PHE A 309GLU A 305ARG A 211VAL A 239 | None | 1.27A | 1m00A-2ywbA:undetectable1m00B-2ywbA:undetectable | 1m00A-2ywbA:21.891m00B-2ywbA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z11 | RIBOSOMAL-PROTEIN-ALANINEACETYLTRANSFERASE (Thermusthermophilus) |
PF13302(Acetyltransf_3) | 4 | TRP A 66PHE A 4GLU A 6VAL A 64 | None | 1.42A | 1m00A-2z11A:undetectable1m00B-2z11A:undetectable | 1m00A-2z11A:17.591m00B-2z11A:17.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ahi | XYLULOSE5-PHOSPHATE/FRUCTOSE6-PHOSPHATEPHOSPHOKETOLASE (Bifidobacteriumbreve) |
PF03894(XFP)PF09363(XFP_C)PF09364(XFP_N) | 4 | TRP A 498GLU A 487MET A 511VAL A 505 | None | 1.22A | 1m00A-3ahiA:undetectable1m00B-3ahiA:undetectable | 1m00A-3ahiA:19.241m00B-3ahiA:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ai7 | XYLULOSE-5-PHOSPHATE/FRUCTOSE-6-PHOSPHATE PHOSPHOKETOLASE (Bifidobacteriumlongum) |
PF03894(XFP)PF09363(XFP_C)PF09364(XFP_N) | 4 | TRP A 498GLU A 487MET A 511VAL A 505 | None | 1.21A | 1m00A-3ai7A:undetectable1m00B-3ai7A:undetectable | 1m00A-3ai7A:18.911m00B-3ai7A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ajx | 3-HEXULOSE-6-PHOSPHATE SYNTHASE (Mycobacteriumgastri) |
PF00215(OMPdecase) | 4 | PHE A1074GLU A1069MET A1060VAL A1106 | None | 1.27A | 1m00A-3ajxA:undetectable1m00B-3ajxA:undetectable | 1m00A-3ajxA:20.381m00B-3ajxA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b7f | GLYCOSYL HYDROLASE,BNR REPEAT (Cupriaviduspinatubonensis) |
no annotation | 4 | TRP A 374GLU A 372VAL A 314TRP A 293 | NoneEDO A 404 ( 3.8A)NoneNone | 1.39A | 1m00A-3b7fA:undetectable1m00B-3b7fA:undetectable | 1m00A-3b7fA:20.651m00B-3b7fA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d2w | TAR DNA-BINDINGPROTEIN 43 (Mus musculus) |
PF00076(RRM_1) | 4 | PHE A 211GLU A 206MET A 202VAL A 220 | None | 1.06A | 1m00A-3d2wA:undetectable1m00B-3d2wA:undetectable | 1m00A-3d2wA:13.541m00B-3d2wA:13.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ddl | XANTHORHODOPSIN (Salinibacterruber) |
PF01036(Bac_rhodopsin) | 4 | TRP A 70PHE A 88GLU A 71VAL A 16 | None | 1.50A | 1m00A-3ddlA:undetectable1m00B-3ddlA:undetectable | 1m00A-3ddlA:20.231m00B-3ddlA:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gyx | ADENYLYLSULFATEREDUCTASE (Desulfovibriogigas) |
PF00890(FAD_binding_2)PF12139(APS-reductase_C)PF13187(Fer4_9) | 4 | TRP B 88GLU A 380ARG A 66VAL A 387 | None | 1.31A | 1m00A-3gyxB:undetectable1m00B-3gyxB:undetectable | 1m00A-3gyxB:16.461m00B-3gyxB:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hzp | NTF2-LIKE PROTEIN OFUNKNOWN FUNCTION (Prochlorococcusmarinus) |
PF12707(DUF3804) | 4 | PHE A 34MET A 20ARG A 118TRP A 51 | 1PE A 131 (-4.5A)1PE A 131 ( 3.8A)1PE A 131 (-3.7A)None | 1.47A | 1m00A-3hzpA:undetectable1m00B-3hzpA:undetectable | 1m00A-3hzpA:14.051m00B-3hzpA:14.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l3p | IPAH9.8 (Shigellaflexneri) |
PF14496(NEL) | 4 | TRP A 274GLU A 314VAL A 258TRP A 261 | None | 1.33A | 1m00A-3l3pA:undetectable1m00B-3l3pA:undetectable | 1m00A-3l3pA:20.701m00B-3l3pA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ma6 | CALMODULIN-DOMAINPROTEIN KINASE 1 (Toxoplasmagondii) |
PF00069(Pkinase) | 4 | TRP A 257PHE A 252ARG A 269VAL A 260 | None | 1.45A | 1m00A-3ma6A:undetectable1m00B-3ma6A:undetectable | 1m00A-3ma6A:21.651m00B-3ma6A:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n3k | UBIQUITINCARBOXYL-TERMINALHYDROLASE 8 (Homo sapiens) |
PF00443(UCH) | 4 | TRP A1001PHE A 946GLU A 908ARG A 944 | None | 1.47A | 1m00A-3n3kA:undetectable1m00B-3n3kA:undetectable | 1m00A-3n3kA:19.741m00B-3n3kA:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nkz | FLAGELLAR PROTEINFLIT (Yersiniaenterocolitica) |
PF05400(FliT) | 4 | GLU A 37MET A 38ARG A 69VAL A 44 | NoneNoneNonePG4 A 122 ( 4.2A) | 1.35A | 1m00A-3nkzA:undetectable1m00B-3nkzA:undetectable | 1m00A-3nkzA:15.401m00B-3nkzA:15.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3owc | PROBABLEACETYLTRANSFERASE (Pseudomonasaeruginosa) |
PF00583(Acetyltransf_1) | 4 | PHE A 121GLU A 119ARG A 175VAL A 92 | None | 1.24A | 1m00A-3owcA:undetectable1m00B-3owcA:undetectable | 1m00A-3owcA:16.391m00B-3owcA:16.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q3u | LIGNIN PEROXIDASE (Trametopsiscervina) |
PF00141(peroxidase)PF11895(Peroxidase_ext) | 4 | TRP A 249PHE A 203MET A 259VAL A 169 | None | 1.28A | 1m00A-3q3uA:undetectable1m00B-3q3uA:undetectable | 1m00A-3q3uA:20.771m00B-3q3uA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rjy | ENDOGLUCANASEFNCEL5A (Fervidobacteriumnodosum) |
PF00150(Cellulase) | 4 | TRP A 146PHE A 162GLU A 187VAL A 149 | None | 1.27A | 1m00A-3rjyA:undetectable1m00B-3rjyA:undetectable | 1m00A-3rjyA:20.181m00B-3rjyA:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ti8 | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 4 | PHE A 305GLU A 265VAL A 240TRP A 239 | None | 1.44A | 1m00A-3ti8A:undetectable1m00B-3ti8A:undetectable | 1m00A-3ti8A:22.151m00B-3ti8A:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uxm | THYMIDYLATE KINASE (Pseudomonasaeruginosa) |
PF02223(Thymidylate_kin) | 4 | PHE A 162GLU A 156ARG A 109VAL A 166 | None MG A 213 (-3.2A)NoneNone | 1.31A | 1m00A-3uxmA:undetectable1m00B-3uxmA:undetectable | 1m00A-3uxmA:20.621m00B-3uxmA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fnq | ALPHA-GALACTOSIDASEAGAB (Geobacillusstearothermophilus) |
PF02065(Melibiase)PF16874(Glyco_hydro_36C)PF16875(Glyco_hydro_36N) | 4 | TRP A 383PHE A 370ARG A 373VAL A 412 | None | 1.44A | 1m00A-4fnqA:undetectable1m00B-4fnqA:undetectable | 1m00A-4fnqA:20.921m00B-4fnqA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g76 | PHOSPHODIESTERASE (Pseudomonasaeruginosa) |
PF14859(Colicin_M) | 4 | TRP A 62PHE A 85MET A 258VAL A 265 | None | 1.32A | 1m00A-4g76A:undetectable1m00B-4g76A:undetectable | 1m00A-4g76A:19.761m00B-4g76A:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pne | METHYLTRANSFERASE-LIKE PROTEIN (Saccharopolysporaspinosa) |
PF08241(Methyltransf_11) | 4 | PHE A 141GLU A 162ARG A 75VAL A 79 | None | 1.36A | 1m00A-4pneA:undetectable1m00B-4pneA:undetectable | 1m00A-4pneA:21.331m00B-4pneA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xj6 | VC0179-LIKE PROTEIN (Escherichiacoli) |
no annotation | 4 | PHE A 264GLU A 266ARG A 276VAL A 305 | None | 1.16A | 1m00A-4xj6A:0.01m00B-4xj6A:undetectable | 1m00A-4xj6A:21.031m00B-4xj6A:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xj6 | VC0179-LIKE PROTEIN (Escherichiacoli) |
no annotation | 4 | TRP A 263PHE A 264GLU A 266VAL A 305 | None | 1.10A | 1m00A-4xj6A:0.01m00B-4xj6A:undetectable | 1m00A-4xj6A:21.031m00B-4xj6A:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ylr | TUBULINPOLYGLUTAMYLASETTLL7 (Homo sapiens) |
PF03133(TTL) | 4 | PHE A 277GLU A 279VAL A 288TRP A 292 | None | 1.41A | 1m00A-4ylrA:undetectable1m00B-4ylrA:undetectable | 1m00A-4ylrA:22.901m00B-4ylrA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ypl | LON PROTEASE (Meiothermustaiwanensis) |
PF00004(AAA)PF05362(Lon_C) | 4 | GLU A 705MET A 713ARG A 709VAL A 762 | None | 1.28A | 1m00A-4yplA:undetectable1m00B-4yplA:undetectable | 1m00A-4yplA:21.321m00B-4yplA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zva | DIGUANYLATE CYCLASEDOSC (Escherichiacoli) |
PF11563(Protoglobin) | 4 | TRP A 12GLU A 11MET A 8VAL A 84 | None | 1.27A | 1m00A-4zvaA:undetectable1m00B-4zvaA:undetectable | 1m00A-4zvaA:18.951m00B-4zvaA:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zvb | DIGUANYLATE CYCLASEDOSC (Escherichiacoli) |
PF11563(Protoglobin) | 4 | TRP A 12GLU A 11MET A 8VAL A 84 | None | 1.35A | 1m00A-4zvbA:undetectable1m00B-4zvbA:undetectable | 1m00A-4zvbA:16.671m00B-4zvbA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b4x | REELIN (Mus musculus) |
PF07974(EGF_2) | 4 | TRP A2654PHE A2555VAL A2595TRP A2641 | None | 1.45A | 1m00A-5b4xA:undetectable1m00B-5b4xA:undetectable | 1m00A-5b4xA:19.941m00B-5b4xA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bs1 | CRRBCX-IIA (Chlamydomonasreinhardtii) |
PF02341(RcbX) | 4 | TRP A 104GLU A 103ARG A 123VAL A 108 | TRP A 104 ( 0.5A)GLU A 103 ( 0.6A)ARG A 123 ( 0.6A)VAL A 108 ( 0.6A) | 1.30A | 1m00A-5bs1A:undetectable1m00B-5bs1A:undetectable | 1m00A-5bs1A:14.561m00B-5bs1A:14.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5by3 | BTGH115A (Bacteroidesthetaiotaomicron) |
PF15979(Glyco_hydro_115) | 4 | TRP A 732GLU A 731ARG A 505VAL A 736 | None | 1.39A | 1m00A-5by3A:undetectable1m00B-5by3A:undetectable | 1m00A-5by3A:19.871m00B-5by3A:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ev7 | CONSERVED DOMAINPROTEIN (Bacillusanthracis) |
PF13402(Peptidase_M60)PF17291(M60-like_N) | 4 | PHE A 350GLU A 345MET A 341VAL A 300 | None | 1.49A | 1m00A-5ev7A:undetectable1m00B-5ev7A:undetectable | 1m00A-5ev7A:20.631m00B-5ev7A:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m8t | 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACIDOXIDASE (Homo sapiens) |
PF00264(Tyrosinase) | 4 | TRP A 414PHE A 411GLU A 413ARG A 225 | None | 1.08A | 1m00A-5m8tA:undetectable1m00B-5m8tA:undetectable | 1m00A-5m8tA:19.871m00B-5m8tA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wq3 | CYTOKININ RIBOSIDE5'-MONOPHOSPHATEPHOSPHORIBOHYDROLASE (Corynebacteriumglutamicum) |
PF03641(Lysine_decarbox) | 4 | PHE A 159MET A 112ARG A 155VAL A 104 | None | 1.44A | 1m00A-5wq3A:undetectable1m00B-5wq3A:undetectable | 1m00A-5wq3A:24.301m00B-5wq3A:24.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x89 | ENDA-LIKEPROTEIN,TRNA-SPLICING ENDONUCLEASE (Methanopyruskandleri) |
no annotation | 4 | PHE A 258GLU A 253MET A 249VAL A 231 | None | 0.98A | 1m00A-5x89A:undetectable1m00B-5x89A:undetectable | 1m00A-5x89A:12.701m00B-5x89A:12.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xf7 | PROTEINDISULFIDE-ISOMERASE-LIKE PROTEIN OF THETESTIS (Homo sapiens) |
no annotation | 4 | PHE A 113GLU A 106ARG A 129VAL A 65 | None | 1.21A | 1m00A-5xf7A:undetectable1m00B-5xf7A:undetectable | 1m00A-5xf7A:13.091m00B-5xf7A:13.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xwd | VH CHAIN OF 059-152VL CHAIN OF 059-152 (Homo sapiens) |
no annotation | 4 | TRP H 49MET H 105VAL D 98TRP D 91 | None | 1.18A | 1m00A-5xwdH:undetectable1m00B-5xwdH:undetectable | 1m00A-5xwdH:10.161m00B-5xwdH:10.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bk1 | UDP-GLYCOSYLTRANSFERASE 79 (Oryza sativa) |
no annotation | 4 | GLU A 322ARG A 331VAL A 317TRP A 316 | NoneNoneUDP A 501 ( 4.8A)None | 1.30A | 1m00A-6bk1A:undetectable1m00B-6bk1A:undetectable | 1m00A-6bk1A:13.481m00B-6bk1A:13.48 |