SIMILAR PATTERNS OF AMINO ACIDS FOR 1LXF_C_BEPC92

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ggz CALMODULIN-RELATED
PROTEIN NB-1

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 LEU A 105
MET A 109
LEU A 112
MET A 124
ILE A 125
VAL A 136
 None
 1.07A 1lxfC-1ggzA:
10.2		 1lxfC-1ggzA:
48.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ggz CALMODULIN-RELATED
PROTEIN NB-1

(Homo sapiens) 		PF13499
(EF-hand_7) 		7 PHE A  19
ILE A  27
LEU A  32
LEU A  39
MET A  51
GLU A  54
VAL A  63
 None
None
None
None
None
None
CA  A 150 ( 4.9A)
 0.94A 1lxfC-1ggzA:
10.2		 1lxfC-1ggzA:
48.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ggz CALMODULIN-RELATED
PROTEIN NB-1

(Homo sapiens) 		PF13499
(EF-hand_7) 		7 PHE A  19
ILE A  27
LEU A  32
MET A  36
LEU A  39
GLU A  54
VAL A  63
 None
None
None
None
None
None
CA  A 150 ( 4.9A)
 0.91A 1lxfC-1ggzA:
10.2		 1lxfC-1ggzA:
48.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ggz CALMODULIN-RELATED
PROTEIN NB-1

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 PHE A  92
LEU A 105
LEU A 112
MET A 124
ILE A 125
VAL A 136
 None
 0.81A 1lxfC-1ggzA:
10.2		 1lxfC-1ggzA:
48.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1m39 CALTRACTIN, ISOFORM
1

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 PHE A 113
ILE A 121
LEU A 126
LEU A 133
ILE A 146
VAL A 157
 None
 1.13A 1lxfC-1m39A:
4.9		 1lxfC-1m39A:
44.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1wrk TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES

(Homo sapiens) 		PF13833
(EF-hand_8) 		7 ILE A  36
LEU A  41
MET A  45
ILE A  61
GLU A  63
VAL A  72
MET A  81
 None
None
TFP  A 202 (-3.6A)
None
None
None
TFP  A 202 ( 3.3A)
 0.91A 1lxfC-1wrkA:
11.4		 1lxfC-1wrkA:
97.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1wrk TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES

(Homo sapiens) 		PF13833
(EF-hand_8) 		7 ILE A  36
LEU A  41
MET A  60
ILE A  61
GLU A  63
VAL A  72
MET A  81
 None
None
TFP  A 202 ( 4.0A)
None
None
None
TFP  A 202 ( 3.3A)
 0.85A 1lxfC-1wrkA:
11.4		 1lxfC-1wrkA:
97.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1wrk TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES

(Homo sapiens) 		PF13833
(EF-hand_8) 		7 ILE A  36
LEU A  48
MET A  60
ILE A  61
GLU A  63
VAL A  72
MET A  81
 None
TFP  A 202 (-4.1A)
TFP  A 202 ( 4.0A)
None
None
None
TFP  A 202 ( 3.3A)
 0.86A 1lxfC-1wrkA:
11.4		 1lxfC-1wrkA:
97.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1wrk TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES

(Homo sapiens) 		PF13833
(EF-hand_8) 		7 ILE A  36
MET A  45
LEU A  48
ILE A  61
GLU A  63
VAL A  72
MET A  81
 None
TFP  A 202 (-3.6A)
TFP  A 202 (-4.1A)
None
None
None
TFP  A 202 ( 3.3A)
 0.92A 1lxfC-1wrkA:
11.4		 1lxfC-1wrkA:
97.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1zot CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		8 ILE B 100
LEU B 105
MET B 109
LEU B 112
GLU B 127
VAL B 136
MET B 144
MET B 145
 None
None
None
None
None
CA  B 800 ( 4.9A)
None
None
 1.06A 1lxfC-1zotB:
8.7		 1lxfC-1zotB:
38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1zot CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		9 PHE B  92
ILE B 100
LEU B 105
MET B 109
LEU B 112
ILE B 125
GLU B 127
VAL B 136
MET B 145
 None
None
None
None
None
None
None
CA  B 800 ( 4.9A)
None
 1.11A 1lxfC-1zotB:
8.7		 1lxfC-1zotB:
38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1zot CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		9 PHE B  92
ILE B 100
LEU B 105
MET B 109
LEU B 112
MET B 124
ILE B 125
VAL B 136
MET B 145
 None
None
None
None
None
None
None
CA  B 800 ( 4.9A)
None
 1.17A 1lxfC-1zotB:
8.7		 1lxfC-1zotB:
38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1zot CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		7 PHE B  92
ILE B 100
LEU B 105
MET B 124
ILE B 125
VAL B 136
MET B 144
 None
None
None
None
None
CA  B 800 ( 4.9A)
None
 1.16A 1lxfC-1zotB:
8.7		 1lxfC-1zotB:
38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2b1u CALMODULIN-LIKE
PROTEIN 5

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 LEU A 103
MET A 107
LEU A 110
MET A 122
GLU A 125
VAL A 134
 None
 1.19A 1lxfC-2b1uA:
3.8		 1lxfC-2b1uA:
35.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f2p CALMODULIN FUSED
WITH
CALMODULIN-BINDING
DOMAIN OF
CALCINEURIN

(Bos taurus) 		PF13499
(EF-hand_7) 		6 PHE A  19
ILE A  27
LEU A  32
MET A  36
LEU A  39
ILE A  52
 None
 0.85A 1lxfC-2f2pA:
10.7		 1lxfC-2f2pA:
62.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f2p CALMODULIN FUSED
WITH
CALMODULIN-BINDING
DOMAIN OF
CALCINEURIN

(Bos taurus) 		PF13499
(EF-hand_7) 		6 PHE A  19
ILE A  27
LEU A  32
MET A  36
LEU A  39
MET A  72
 None
 1.02A 1lxfC-2f2pA:
10.7		 1lxfC-2f2pA:
62.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f2p CALMODULIN FUSED
WITH
CALMODULIN-BINDING
DOMAIN OF
CALCINEURIN

(Bos taurus) 		PF13499
(EF-hand_7) 		6 PHE A  19
ILE A  27
MET A  36
LEU A  39
MET A  51
ILE A  52
 None
 0.96A 1lxfC-2f2pA:
10.7		 1lxfC-2f2pA:
62.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f2p CALMODULIN FUSED
WITH
CALMODULIN-BINDING
DOMAIN OF
CALCINEURIN

(Bos taurus) 		PF13499
(EF-hand_7) 		6 PHE A  19
ILE A  27
MET A  36
LEU A  39
MET A  51
MET A  72
 None
 1.17A 1lxfC-2f2pA:
10.7		 1lxfC-2f2pA:
62.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f2p CALMODULIN FUSED
WITH
CALMODULIN-BINDING
DOMAIN OF
CALCINEURIN

(Bos taurus) 		PF13499
(EF-hand_7) 		6 PHE A  19
LEU A  32
MET A  36
LEU A  39
GLU A  54
MET A  72
 None
 1.14A 1lxfC-2f2pA:
10.7		 1lxfC-2f2pA:
62.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f2p CALMODULIN FUSED
WITH
CALMODULIN-BINDING
DOMAIN OF
CALCINEURIN

(Bos taurus) 		PF13499
(EF-hand_7) 		6 PHE A  19
LEU A  32
MET A  36
LEU A  39
ILE A  52
GLU A  54
 None
 0.99A 1lxfC-2f2pA:
10.7		 1lxfC-2f2pA:
62.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f2p CALMODULIN FUSED
WITH
CALMODULIN-BINDING
DOMAIN OF
CALCINEURIN

(Bos taurus) 		PF13499
(EF-hand_7) 		6 PHE A  92
ILE A 100
LEU A 105
VAL A 136
MET A 144
MET A 145
 None
None
None
CA  A1004 ( 4.9A)
None
None
 1.06A 1lxfC-2f2pA:
10.7		 1lxfC-2f2pA:
62.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ggm CENTRIN-2

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 ILE A 121
LEU A 133
MET A 145
ILE A 146
GLU A 148
VAL A 157
 None
 0.92A 1lxfC-2ggmA:
8.5		 1lxfC-2ggmA:
29.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ggm CENTRIN-2

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 ILE A 121
MET A 145
ILE A 146
GLU A 148
VAL A 157
MET A 166
 None
 0.94A 1lxfC-2ggmA:
8.5		 1lxfC-2ggmA:
29.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ggm CENTRIN-2

(Homo sapiens) 		PF13499
(EF-hand_7) 		7 PHE A 113
ILE A 121
LEU A 126
MET A 145
ILE A 146
VAL A 157
MET A 166
 None
 0.97A 1lxfC-2ggmA:
8.5		 1lxfC-2ggmA:
29.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jjz IONIZED
CALCIUM-BINDING
ADAPTER MOLECULE 2

(Homo sapiens) 		no annotation 6 ILE B  67
LEU B  72
MET B  76
LEU B  79
ILE B  92
MET B 111
 None
 1.08A 1lxfC-2jjzB:
7.2		 1lxfC-2jjzB:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jjz IONIZED
CALCIUM-BINDING
ADAPTER MOLECULE 2

(Homo sapiens) 		no annotation 7 ILE B  67
LEU B  72
MET B  76
LEU B  79
MET B  91
ILE B  92
GLU B  94
 None
 0.94A 1lxfC-2jjzB:
7.2		 1lxfC-2jjzB:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jjz IONIZED
CALCIUM-BINDING
ADAPTER MOLECULE 2

(Homo sapiens) 		no annotation 6 PHE B  59
ILE B  67
LEU B  72
MET B  76
ILE B  92
MET B 111
 None
 1.11A 1lxfC-2jjzB:
7.2		 1lxfC-2jjzB:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jjz IONIZED
CALCIUM-BINDING
ADAPTER MOLECULE 2

(Homo sapiens) 		no annotation 7 PHE B  59
ILE B  67
LEU B  72
MET B  76
MET B  91
ILE B  92
GLU B  94
 None
 0.99A 1lxfC-2jjzB:
7.2		 1lxfC-2jjzB:
25.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2k2i CENTRIN-2

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 PHE A 113
ILE A 121
LEU A 126
GLU A 148
VAL A 157
MET A 166
 None
 0.97A 1lxfC-2k2iA:
8.7		 1lxfC-2k2iA:
44.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2k2i CENTRIN-2

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 PHE A 113
ILE A 121
LEU A 126
ILE A 146
GLU A 148
VAL A 157
 None
 0.90A 1lxfC-2k2iA:
8.7		 1lxfC-2k2iA:
44.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2k7d CALCIUM-BINDING
PROTEIN 1

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 ILE A 119
LEU A 124
MET A 128
LEU A 131
VAL A 156
MET A 165
 None
 1.14A 1lxfC-2k7dA:
7.2		 1lxfC-2k7dA:
39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2kn2 CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		6 PHE A  18
ILE A  26
LEU A  31
MET A  35
LEU A  38
MET A  50
 None
 0.95A 1lxfC-2kn2A:
9.4		 1lxfC-2kn2A:
36.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2kn2 CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		7 PHE A  18
ILE A  26
LEU A  31
MET A  35
MET A  50
ILE A  51
VAL A  62
 None
None
None
None
None
None
CA  A 209 ( 4.5A)
 0.98A 1lxfC-2kn2A:
9.4		 1lxfC-2kn2A:
36.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2kn2 CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		7 PHE A  18
ILE A  26
LEU A  31
MET A  35
MET A  50
VAL A  62
MET A  71
 None
None
None
None
None
CA  A 209 ( 4.5A)
None
 0.98A 1lxfC-2kn2A:
9.4		 1lxfC-2kn2A:
36.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2kz2 CALMODULIN

(Gallus gallus) 		PF13499
(EF-hand_7) 		6 ILE A 100
LEU A 105
MET A 109
VAL A 136
MET A 144
MET A 145
 None
None
None
CA  A 150 (-4.1A)
None
None
 1.14A 1lxfC-2kz2A:
7.2		 1lxfC-2kz2A:
35.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l1w CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		6 PHE A  92
ILE A 100
LEU A 105
GLU A 127
VAL A 136
MET A 145
 None
None
None
None
CA  A 234 ( 4.6A)
None
 1.00A 1lxfC-2l1wA:
8.3		 1lxfC-2l1wA:
42.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l1w CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		6 PHE A  92
ILE A 100
LEU A 105
MET A 109
GLU A 127
VAL A 136
 None
None
None
None
None
CA  A 234 ( 4.6A)
 0.88A 1lxfC-2l1wA:
8.3		 1lxfC-2l1wA:
42.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l1w CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		6 PHE A  92
ILE A 100
LEU A 105
MET A 109
MET A 124
VAL A 136
 None
None
None
None
None
CA  A 234 ( 4.6A)
 0.94A 1lxfC-2l1wA:
8.3		 1lxfC-2l1wA:
42.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l1w CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		6 PHE A  92
ILE A 100
LEU A 105
MET A 109
VAL A 136
MET A 144
 None
None
None
None
CA  A 234 ( 4.6A)
None
 0.83A 1lxfC-2l1wA:
8.3		 1lxfC-2l1wA:
42.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l1w CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		6 PHE A  92
ILE A 100
LEU A 105
VAL A 136
MET A 144
MET A 145
 None
None
None
CA  A 234 ( 4.6A)
None
None
 0.84A 1lxfC-2l1wA:
8.3		 1lxfC-2l1wA:
42.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lmv CALMODULIN-RELATED
PROTEIN 97A

(Drosophila
melanogaster) 		PF13499
(EF-hand_7) 		6 LEU A 105
MET A 109
LEU A 112
MET A 124
ILE A 125
GLU A 127
 None
 1.06A 1lxfC-2lmvA:
8.4		 1lxfC-2lmvA:
27.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2lv7 CALCIUM-BINDING
PROTEIN 7

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 PHE A  42
ILE A  53
LEU A  58
LEU A  65
ILE A  78
VAL A  89
 None
None
None
None
None
CA  A 202 ( 4.2A)
 1.07A 1lxfC-2lv7A:
6.8		 1lxfC-2lv7A:
34.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2n6a HUMAN
CALMODULIN/CONNEXIN-
36 PEPTIDE HYBRID

(Homo sapiens) 		PF13499
(EF-hand_7) 		8 PHE A  92
ILE A 100
LEU A 105
MET A 109
MET A 124
ILE A 125
VAL A 136
MET A 144
 None
 1.16A 1lxfC-2n6aA:
8.7		 1lxfC-2n6aA:
57.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2obh CENTRIN-2

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 ILE A 121
LEU A 133
MET A 145
ILE A 146
GLU A 148
VAL A 157
 None
None
None
None
None
CA  A1001 ( 4.9A)
 1.05A 1lxfC-2obhA:
7.8		 1lxfC-2obhA:
31.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ro9 CALMODULIN-2

(Glycine max) 		PF13499
(EF-hand_7) 		7 PHE A  92
ILE A 100
LEU A 105
MET A 109
LEU A 112
MET A 124
ILE A 125
 None
 1.31A 1lxfC-2ro9A:
9.2		 1lxfC-2ro9A:
39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ro9 CALMODULIN-2

(Glycine max) 		PF13499
(EF-hand_7) 		7 PHE A  92
ILE A 100
LEU A 105
MET A 109
MET A 124
ILE A 125
MET A 145
 None
 1.21A 1lxfC-2ro9A:
9.2		 1lxfC-2ro9A:
39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ro9 CALMODULIN-2

(Glycine max) 		PF13499
(EF-hand_7) 		7 PHE A  92
LEU A 105
MET A 109
MET A 124
ILE A 125
GLU A 127
MET A 145
 None
 1.43A 1lxfC-2ro9A:
9.2		 1lxfC-2ro9A:
39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2rob CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		7 LEU A 105
MET A 109
LEU A 112
MET A 124
ILE A 125
GLU A 127
VAL A 136
 None
 1.02A 1lxfC-2robA:
9.1		 1lxfC-2robA:
42.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2w49 TROPONIN C, SKELETAL
MUSCLE

(Gallus gallus) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		6 PHE 0  28
ILE 0  36
LEU 0  41
LEU 0  48
GLU 0  63
MET 0  81
 None
 0.86A 1lxfC-2w490:
11.2		 1lxfC-2w490:
42.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2w49 TROPONIN C, SKELETAL
MUSCLE

(Gallus gallus) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		6 PHE 0  28
ILE 0  36
LEU 0  41
LEU 0  48
ILE 0  61
GLU 0  63
 None
 0.81A 1lxfC-2w490:
11.2		 1lxfC-2w490:
42.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2w49 TROPONIN C, SKELETAL
MUSCLE

(Gallus gallus) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		6 PHE 0  28
ILE 0  36
LEU 0  41
MET 0  45
LEU 0  48
ILE 0  61
 None
 0.80A 1lxfC-2w490:
11.2		 1lxfC-2w490:
42.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2w49 TROPONIN C, SKELETAL
MUSCLE

(Gallus gallus) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		6 PHE 0  28
ILE 0  36
LEU 0  41
MET 0  45
LEU 0  48
MET 0  81
 None
 0.76A 1lxfC-2w490:
11.2		 1lxfC-2w490:
42.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3b32 CALMODULIN

(Rattus
norvegicus) 		PF13499
(EF-hand_7) 		6 PHE A  19
ILE A  27
LEU A  32
MET A  36
ILE A  52
GLU A  54
 None
 0.85A 1lxfC-3b32A:
10.0		 1lxfC-3b32A:
59.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3b32 CALMODULIN

(Rattus
norvegicus) 		PF13499
(EF-hand_7) 		6 PHE A  19
ILE A  27
LEU A  32
MET A  36
MET A  51
ILE A  52
 None
 0.88A 1lxfC-3b32A:
10.0		 1lxfC-3b32A:
59.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA

(Aequorea
victoria;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		7 ILE A 403
LEU A 408
MET A 412
LEU A 415
MET A 427
ILE A 428
VAL A 439
 None
 1.10A 1lxfC-3evrA:
8.9		 1lxfC-3evrA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA

(Aequorea
victoria;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		6 PHE A 322
ILE A 330
LEU A 335
MET A 339
ILE A 355
MET A 374
 None
 1.20A 1lxfC-3evrA:
8.9		 1lxfC-3evrA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA

(Aequorea
victoria;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		7 PHE A 395
ILE A 403
LEU A 408
ILE A 428
GLU A 430
VAL A 439
MET A 447
 None
 0.98A 1lxfC-3evrA:
8.9		 1lxfC-3evrA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA

(Aequorea
victoria;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		8 PHE A 395
ILE A 403
LEU A 408
MET A 412
ILE A 428
VAL A 439
MET A 447
MET A 448
 None
 1.04A 1lxfC-3evrA:
8.9		 1lxfC-3evrA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA

(Aequorea
victoria;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		8 PHE A 395
ILE A 403
LEU A 408
MET A 412
MET A 427
ILE A 428
VAL A 439
MET A 448
 None
 1.13A 1lxfC-3evrA:
8.9		 1lxfC-3evrA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fwb CELL DIVISION
CONTROL PROTEIN 31

(Saccharomyces
cerevisiae) 		PF13499
(EF-hand_7) 		6 PHE A 105
ILE A 113
LEU A 118
LEU A 125
MET A 137
ILE A 138
 None
 0.86A 1lxfC-3fwbA:
7.7		 1lxfC-3fwbA:
24.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ifk CALMODULIN

(Rattus
norvegicus) 		PF13499
(EF-hand_7) 		7 PHE A  19
ILE A  27
LEU A  32
MET A  36
ILE A  52
MET A  71
MET A  72
 None
 1.05A 1lxfC-3ifkA:
9.6		 1lxfC-3ifkA:
61.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ifk CALMODULIN

(Rattus
norvegicus) 		PF13499
(EF-hand_7) 		7 PHE A  19
ILE A  27
LEU A  32
MET A  36
LEU A  39
MET A  51
ILE A  52
 None
 0.83A 1lxfC-3ifkA:
9.6		 1lxfC-3ifkA:
61.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ifk CALMODULIN

(Rattus
norvegicus) 		PF13499
(EF-hand_7) 		7 PHE A  19
ILE A  27
LEU A  32
MET A  36
MET A  51
ILE A  52
MET A  72
 None
 1.09A 1lxfC-3ifkA:
9.6		 1lxfC-3ifkA:
61.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kf9 CALTRACTIN

(Scherffelia
dubia) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		7 PHE A  36
ILE A  44
LEU A  49
MET A  53
MET A  68
ILE A  69
MET A  88
 None
 1.27A 1lxfC-3kf9A:
9.6		 1lxfC-3kf9A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kf9 CALTRACTIN

(Scherffelia
dubia) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		6 PHE A  36
ILE A  44
MET A  53
LEU A  56
MET A  68
ILE A  69
 None
 1.04A 1lxfC-3kf9A:
9.6		 1lxfC-3kf9A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kf9 CALTRACTIN

(Scherffelia
dubia) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		7 PHE A 109
ILE A 117
LEU A 122
ILE A 142
GLU A 144
VAL A 153
MET A 162
 None
 0.88A 1lxfC-3kf9A:
9.6		 1lxfC-3kf9A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kf9 CALTRACTIN

(Scherffelia
dubia) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		7 PHE A 109
ILE A 117
LEU A 122
MET A 141
ILE A 142
VAL A 153
MET A 162
 None
 0.83A 1lxfC-3kf9A:
9.6		 1lxfC-3kf9A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o4y CALCIUM-DEPENDENT
PROTEIN KINASE 3

(Plasmodium
vivax) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		6 PHE A 134
ILE A 142
LEU A 147
ILE A 172
MET A 191
MET A 192
 None
 1.05A 1lxfC-3o4yA:
5.7		 1lxfC-3o4yA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qrx CENTRIN

(Chlamydomonas
reinhardtii) 		PF13499
(EF-hand_7) 		6 ILE A 118
LEU A 123
LEU A 130
MET A 142
ILE A 143
GLU A 145
 None
 1.10A 1lxfC-3qrxA:
10.2		 1lxfC-3qrxA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qrx CENTRIN

(Chlamydomonas
reinhardtii) 		PF13499
(EF-hand_7) 		7 PHE A  37
ILE A  45
LEU A  50
LEU A  57
MET A  69
ILE A  70
MET A  89
 None
 1.19A 1lxfC-3qrxA:
10.2		 1lxfC-3qrxA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qrx CENTRIN

(Chlamydomonas
reinhardtii) 		PF13499
(EF-hand_7) 		6 PHE A  37
ILE A  45
LEU A  50
LEU A  57
MET A  69
MET A  90
 None
 1.11A 1lxfC-3qrxA:
10.2		 1lxfC-3qrxA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qrx CENTRIN

(Chlamydomonas
reinhardtii) 		PF13499
(EF-hand_7) 		7 PHE A  37
ILE A  45
LEU A  50
MET A  54
LEU A  57
MET A  69
ILE A  70
 None
 1.09A 1lxfC-3qrxA:
10.2		 1lxfC-3qrxA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qrx CENTRIN

(Chlamydomonas
reinhardtii) 		PF13499
(EF-hand_7) 		7 PHE A  37
LEU A  50
LEU A  57
MET A  69
ILE A  70
GLU A  72
MET A  89
 None
 1.21A 1lxfC-3qrxA:
10.2		 1lxfC-3qrxA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qrx CENTRIN

(Chlamydomonas
reinhardtii) 		PF13499
(EF-hand_7) 		7 PHE A  37
LEU A  50
MET A  54
LEU A  57
MET A  69
ILE A  70
GLU A  72
 None
 1.12A 1lxfC-3qrxA:
10.2		 1lxfC-3qrxA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0k RCAMP

(Entacmaea
quadricolor) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		6 ILE A 321
LEU A 326
MET A 330
ILE A 346
MET A 365
MET A 366
 None
 1.18A 1lxfC-3u0kA:
8.9		 1lxfC-3u0kA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0k RCAMP

(Entacmaea
quadricolor) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		6 PHE A 313
ILE A 321
LEU A 326
MET A 330
ILE A 346
MET A 366
 None
 1.01A 1lxfC-3u0kA:
8.9		 1lxfC-3u0kA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0k RCAMP

(Entacmaea
quadricolor) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		6 PHE A 313
LEU A 326
MET A 330
ILE A 346
GLU A 348
MET A 366
 None
 1.21A 1lxfC-3u0kA:
8.9		 1lxfC-3u0kA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0k RCAMP

(Entacmaea
quadricolor) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		8 PHE A 386
ILE A 394
LEU A 399
LEU A 406
GLU A 421
VAL A 430
MET A 438
MET A 439
 None
 1.02A 1lxfC-3u0kA:
8.9		 1lxfC-3u0kA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0k RCAMP

(Entacmaea
quadricolor) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		8 PHE A 386
ILE A 394
LEU A 399
LEU A 406
ILE A 419
GLU A 421
VAL A 430
MET A 439
 None
 1.03A 1lxfC-3u0kA:
8.9		 1lxfC-3u0kA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0k RCAMP

(Entacmaea
quadricolor) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		8 PHE A 386
ILE A 394
LEU A 399
LEU A 406
MET A 418
ILE A 419
VAL A 430
MET A 439
 None
 0.99A 1lxfC-3u0kA:
8.9		 1lxfC-3u0kA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0k RCAMP

(Entacmaea
quadricolor) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		8 PHE A 386
ILE A 394
LEU A 399
MET A 403
LEU A 406
GLU A 421
VAL A 430
MET A 438
 None
 1.05A 1lxfC-3u0kA:
8.9		 1lxfC-3u0kA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0k RCAMP

(Entacmaea
quadricolor) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		8 PHE A 386
ILE A 394
LEU A 399
MET A 403
LEU A 406
ILE A 419
GLU A 421
VAL A 430
 None
 1.08A 1lxfC-3u0kA:
8.9		 1lxfC-3u0kA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0k RCAMP

(Entacmaea
quadricolor) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		8 PHE A 386
ILE A 394
LEU A 399
MET A 403
LEU A 406
MET A 418
ILE A 419
VAL A 430
 None
 1.04A 1lxfC-3u0kA:
8.9		 1lxfC-3u0kA:
16.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gow CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		7 ILE D 100
LEU D 105
MET D 109
MET D 124
ILE D 125
VAL D 136
MET D 145
 ILE  D 100 ( 0.7A)
LEU  D 105 ( 0.6A)
MET  D 109 ( 0.0A)
MET  D 124 ( 0.0A)
ILE  D 125 ( 0.4A)
VAL  D 136 ( 0.6A)
MET  D 145 ( 0.0A)
 1.07A 1lxfC-4gowD:
9.8		 1lxfC-4gowD:
67.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gow CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		7 LEU D 105
MET D 109
MET D 124
ILE D 125
VAL D 136
MET D 144
MET D 145
 LEU  D 105 ( 0.6A)
MET  D 109 ( 0.0A)
MET  D 124 ( 0.0A)
ILE  D 125 ( 0.4A)
VAL  D 136 ( 0.6A)
MET  D 144 ( 0.0A)
MET  D 145 ( 0.0A)
 1.31A 1lxfC-4gowD:
9.8		 1lxfC-4gowD:
67.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gow CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		7 PHE D  92
ILE D 100
LEU D 105
MET D 124
ILE D 125
VAL D 136
MET D 145
 PHE  D  92 ( 1.3A)
ILE  D 100 ( 0.7A)
LEU  D 105 ( 0.6A)
MET  D 124 ( 0.0A)
ILE  D 125 ( 0.4A)
VAL  D 136 ( 0.6A)
MET  D 145 ( 0.0A)
 0.78A 1lxfC-4gowD:
9.8		 1lxfC-4gowD:
67.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gow CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 PHE D  92
LEU D 105
MET D 124
ILE D 125
GLU D 127
VAL D 136
 PHE  D  92 ( 1.3A)
LEU  D 105 ( 0.6A)
MET  D 124 ( 0.0A)
ILE  D 125 ( 0.4A)
GLU  D 127 ( 0.6A)
VAL  D 136 ( 0.6A)
 0.94A 1lxfC-4gowD:
9.8		 1lxfC-4gowD:
67.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i2y RGECO1

(Discosoma sp.;
Gallus gallus;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		6 PHE A 322
ILE A 330
LEU A 335
MET A 339
ILE A 355
MET A 374
 None
 1.06A 1lxfC-4i2yA:
8.0		 1lxfC-4i2yA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i2y RGECO1

(Discosoma sp.;
Gallus gallus;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		6 PHE A 322
ILE A 330
LEU A 335
MET A 339
MET A 354
ILE A 355
 None
 0.82A 1lxfC-4i2yA:
8.0		 1lxfC-4i2yA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i2y RGECO1

(Discosoma sp.;
Gallus gallus;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		9 PHE A 395
ILE A 403
LEU A 408
MET A 412
LEU A 415
MET A 427
ILE A 428
VAL A 439
MET A 448
 None
 1.06A 1lxfC-4i2yA:
8.0		 1lxfC-4i2yA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i2y RGECO1

(Discosoma sp.;
Gallus gallus;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		7 PHE A 395
ILE A 403
LEU A 408
MET A 412
VAL A 439
MET A 447
MET A 448
 None
 0.97A 1lxfC-4i2yA:
8.0		 1lxfC-4i2yA:
17.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4q57 CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 PHE A  19
ILE A  27
LEU A  32
MET A  36
ILE A  52
GLU A  54
 None
 0.85A 1lxfC-4q57A:
8.8		 1lxfC-4q57A:
55.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wpx CELL DIVISION
CONTROL PROTEIN
31-LIKE PROTEIN

(Chaetomium
thermophilum) 		PF00036
(EF-hand_1)
PF13499
(EF-hand_7) 		7 PHE A 120
ILE A 128
LEU A 133
MET A 152
ILE A 153
VAL A 164
MET A 173
 None
 0.93A 1lxfC-4wpxA:
7.7		 1lxfC-4wpxA:
20.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5coc IMMUNOGLOBULIN
G-BINDING PROTEIN
A,CALMODULIN

(Homo sapiens;
Staphylococcus
aureus) 		PF02216
(B)
PF13499
(EF-hand_7) 		7 PHE A1020
ILE A1028
LEU A1033
MET A1037
MET A1052
ILE A1053
GLU A1055
 None
 1.08A 1lxfC-5cocA:
9.2		 1lxfC-5cocA:
40.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d43 CENTRIN-1

(Mus musculus) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		7 PHE A 113
ILE A 121
LEU A 126
MET A 145
ILE A 146
VAL A 157
MET A 166
 None
None
None
None
None
CA  A1204 ( 4.9A)
None
 0.84A 1lxfC-5d43A:
9.9		 1lxfC-5d43A:
28.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i2q EF-HAND
DOMAIN-CONTAINING
PROTEIN D2

(Homo sapiens) 		PF13405
(EF-hand_6) 		6 ILE A 112
LEU A 117
MET A 121
LEU A 124
MET A 136
ILE A 137
 None
 1.13A 1lxfC-5i2qA:
9.9		 1lxfC-5i2qA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ukg K-GECO

(Entacmaea
quadricolor) 		no annotation 6 PHE A 284
ILE A 292
LEU A 297
MET A 301
MET A 316
ILE A 317
 None
 1.05A 1lxfC-5ukgA:
9.7		 1lxfC-5ukgA:
19.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5w88 TROPONIN C, TROPONIN
I

(Homo sapiens) 		PF00992
(Troponin)
PF13833
(EF-hand_8) 		9 PHE A  27
ILE A  36
LEU A  41
MET A  45
LEU A  48
MET A  60
ILE A  61
GLU A  63
VAL A  72
 9XG  A 201 (-3.8A)
9XG  A 201 ( 3.3A)
9XG  A 201 (-3.9A)
9XG  A 201 (-2.4A)
9XG  A 201 ( 4.8A)
9XG  A 201 (-4.0A)
9XG  A 201 ( 4.0A)
None
9XG  A 201 (-3.8A)
 0.84A 1lxfC-5w88A:
9.8		 1lxfC-5w88A:
97.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5w88 TROPONIN C, TROPONIN
I

(Homo sapiens) 		PF00992
(Troponin)
PF13833
(EF-hand_8) 		6 PHE A  27
LEU A  41
MET A  45
LEU A  48
GLU A  63
MET A  80
 9XG  A 201 (-3.8A)
9XG  A 201 (-3.9A)
9XG  A 201 (-2.4A)
9XG  A 201 ( 4.8A)
None
9XG  A 201 (-4.0A)
 1.00A 1lxfC-5w88A:
9.8		 1lxfC-5w88A:
97.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wea PROTEIN ARGONAUTE-2

(Homo sapiens) 		no annotation 6 PHE A 666
ILE A 687
LEU A 642
MET A 645
GLU A 648
CYH A 626
 None
 1.14A 1lxfC-5weaA:
undetectable		 1lxfC-5weaA:
20.22