SIMILAR PATTERNS OF AMINO ACIDS FOR 1KT3_A_RTLA184
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bxn | PROTEIN (RIBULOSEBISPHOSPHATECARBOXYLASE LARGECHAIN) (Cupriavidusnecator) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 4 | LEU A 402MET A 269TYR A 242LEU A 200 | None | 1.03A | 1kt3A-1bxnA:0.0 | 1kt3A-1bxnA:18.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cg4 | PROTEIN(ADENYLOSUCCINATESYNTHETASE) (Escherichiacoli) |
PF00709(Adenylsucc_synt) | 4 | LEU A 146LEU A 151MET A 80LEU A 187 | None | 1.09A | 1kt3A-1cg4A:0.0 | 1kt3A-1cg4A:18.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ddz | CARBONIC ANHYDRASE (Porphyridiumpurpureum) |
PF00484(Pro_CA) | 4 | LEU A 222LEU A 227TYR A 448GLN A 443 | None | 0.97A | 1kt3A-1ddzA:0.0 | 1kt3A-1ddzA:16.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gju | MALTODEXTRINGLYCOSYLTRANSFERASE (Thermotogamaritima) |
PF00128(Alpha-amylase)PF09083(DUF1923) | 4 | LEU A 25LEU A 125TYR A 97LEU A 543 | None | 1.10A | 1kt3A-1gjuA:undetectable | 1kt3A-1gjuA:14.24 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1iiu | PLASMARETINOL-BINDINGPROTEIN (Gallus gallus) |
PF00061(Lipocalin) | 7 | LEU A 35LEU A 37MET A 73MET A 88TYR A 90LEU A 97GLN A 98 | RTL A 176 (-4.5A)RTL A 176 ( 4.5A)RTL A 176 ( 4.0A)RTL A 176 (-3.4A)RTL A 176 ( 4.0A)RTL A 176 (-4.0A)RTL A 176 (-3.8A) | 0.40A | 1kt3A-1iiuA:28.1 | 1kt3A-1iiuA:79.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iwa | RIBULOSE-1,5-BISPHOSPHATECARBOXYLASE/OXYGENASE LARGE SUBUNIT (Galdieriapartita) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 4 | LEU A 400MET A 266TYR A 239LEU A 197 | None | 1.02A | 1kt3A-1iwaA:undetectable | 1kt3A-1iwaA:17.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mhz | METHANEMONOOXYGENASEHYDROXYLASE (Methylosinustrichosporium) |
PF02332(Phenol_Hydrox) | 4 | LEU D 448TYR D 464LEU D 458GLN D 456 | None | 1.06A | 1kt3A-1mhzD:0.0 | 1kt3A-1mhzD:17.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pv5 | HYPOTHETICAL PROTEINYWQG (Bacillussubtilis) |
PF09234(DUF1963) | 4 | MET A 60TYR A 86LEU A 83GLN A 84 | None | 1.07A | 1kt3A-1pv5A:0.0 | 1kt3A-1pv5A:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rbl | RIBULOSE 1,5BISPHOSPHATECARBOXYLASE/OXYGENASE (LARGE CHAIN) (Synechococcuselongatus) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 4 | LEU A 400MET A 266TYR A 239LEU A 197 | None | 1.07A | 1kt3A-1rblA:0.0 | 1kt3A-1rblA:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1su3 | INTERSTITIALCOLLAGENASE (Homo sapiens) |
PF00045(Hemopexin)PF00413(Peptidase_M10)PF01471(PG_binding_1) | 4 | LEU A 73LEU A 64TYR A 37LEU A 84 | None | 1.09A | 1kt3A-1su3A:undetectable | 1kt3A-1su3A:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1svd | RIBULOSE-1,5-BISPHOSPHATECARBOXYLASE/OXYGENASE LARGE SUBUNIT (Halothiobacillusneapolitanus) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 4 | LEU A 393MET A 259TYR A 232LEU A 190 | None | 1.06A | 1kt3A-1svdA:undetectable | 1kt3A-1svdA:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u84 | HYPOTHETICAL PROTEIN (Geobacillusstearothermophilus) |
PF08958(DUF1871) | 4 | LEU A 9LEU A 11TYR A 39LEU A 75 | None | 0.94A | 1kt3A-1u84A:undetectable | 1kt3A-1u84A:23.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v9k | RIBOSOMAL LARGESUBUNITPSEUDOURIDINESYNTHASE C (Escherichiacoli) |
PF00849(PseudoU_synth_2) | 4 | LEU A 160LEU A 152MET A 172LEU A 167 | None | 1.09A | 1kt3A-1v9kA:undetectable | 1kt3A-1v9kA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vma | CELL DIVISIONPROTEIN FTSY (Thermotogamaritima) |
PF00448(SRP54)PF02881(SRP54_N) | 4 | LEU A 76LEU A 71TYR A 55LEU A 257 | None | 1.05A | 1kt3A-1vmaA:undetectable | 1kt3A-1vmaA:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x9s | DNA POLYMERASE (Escherichiavirus T7) |
PF00476(DNA_pol_A) | 4 | LEU A 479LEU A 481TYR A 530LEU A 614 | None | 0.97A | 1kt3A-1x9sA:undetectable | 1kt3A-1x9sA:11.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xls | RETINOIC ACIDRECEPTOR RXR-ALPHAORPHAN NUCLEARRECEPTOR NR1I3 (Homo sapiens;Mus musculus) |
PF00104(Hormone_recep)PF00104(Hormone_recep) | 4 | LEU E 300LEU E 302MET E 323LEU A 420 | None | 1.06A | 1kt3A-1xlsE:undetectable | 1kt3A-1xlsE:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xvi | PUTATIVEMANNOSYL-3-PHOSPHOGLYCERATE PHOSPHATASE (Escherichiacoli) |
PF08282(Hydrolase_3) | 4 | LEU A 14LEU A 19MET A 54LEU A 45 | None | 1.01A | 1kt3A-1xviA:undetectable | 1kt3A-1xviA:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y7e | PROBABLE M18-FAMILYAMINOPEPTIDASE 1 (Borreliellaburgdorferi) |
PF02127(Peptidase_M18) | 4 | LEU A 10TYR A 446LEU A 19GLN A 17 | None | 0.96A | 1kt3A-1y7eA:undetectable | 1kt3A-1y7eA:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yp0 | NUCLEAR RECEPTORSUBFAMILY 5, GROUPA, MEMBER 1 (Mus musculus) |
PF00104(Hormone_recep) | 4 | LEU A 229MET A 285LEU A 231GLN A 233 | None | 0.99A | 1kt3A-1yp0A:undetectable | 1kt3A-1yp0A:23.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a3l | AMP DEAMINASE (Arabidopsisthaliana) |
PF00962(A_deaminase) | 4 | LEU A 729LEU A 355LEU A 697GLN A 699 | None | 0.93A | 1kt3A-2a3lA:undetectable | 1kt3A-2a3lA:12.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a8v | RNA BINDING DOMAINOF RHO TRANSCRIPTIONTERMINATION FACTOR (Escherichiacoli) |
PF07497(Rho_RNA_bind)PF07498(Rho_N) | 5 | LEU A 23LEU A 17MET A 1LEU A 39GLN A 41 | None | 1.28A | 1kt3A-2a8vA:undetectable | 1kt3A-2a8vA:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2abj | BRANCHED-CHAIN-AMINO-ACIDAMINOTRANSFERASE,CYTOSOLIC (Homo sapiens) |
PF01063(Aminotran_4) | 4 | LEU A 96MET A 115LEU A 135GLN A 140 | None | 1.10A | 1kt3A-2abjA:undetectable | 1kt3A-2abjA:16.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f6k | METAL-DEPENDENTHYDROLASE (Lactobacillusplantarum) |
PF04909(Amidohydro_2) | 4 | LEU A 188MET A 233TYR A 230LEU A 210 | None | 0.99A | 1kt3A-2f6kA:undetectable | 1kt3A-2f6kA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gie | TYPE II RESTRICTIONENZYME HINCII (Haemophilusinfluenzae) |
PF09226(Endonuc-HincII) | 4 | LEU A 79LEU A 60TYR A 123LEU A 86 | None | 1.10A | 1kt3A-2gieA:undetectable | 1kt3A-2gieA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h3g | BIOSYNTHETIC PROTEIN (Bacillusanthracis) |
PF03309(Pan_kinase) | 4 | LEU X 47LEU X 42MET X 28LEU X 14 | None | 1.05A | 1kt3A-2h3gX:undetectable | 1kt3A-2h3gX:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2n8o | BACTERIOCIN AUREOCINA53 (Staphylococcusaureus) |
PF11758(Bacteriocin_IIi) | 4 | LEU A 38LEU A 45TYR A 13LEU A 7 | None | 1.06A | 1kt3A-2n8oA:undetectable | 1kt3A-2n8oA:15.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p1n | SKP1-LIKE PROTEIN 1A (Arabidopsisthaliana) |
PF01466(Skp1)PF03931(Skp1_POZ) | 4 | LEU A 114LEU A 116MET A 91LEU A 101 | None | 1.09A | 1kt3A-2p1nA:undetectable | 1kt3A-2p1nA:24.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p4f | SIMILAR TO SP|P32453SACCHAROMYCESCEREVISIAE YNL315CATP11 ([Candida]glabrata) |
PF06644(ATP11) | 4 | LEU A 158MET A 146TYR A 257LEU A 273 | None | 1.09A | 1kt3A-2p4fA:undetectable | 1kt3A-2p4fA:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qty | POLY(ADP-RIBOSE)GLYCOHYDROLASE ARH3 (Mus musculus) |
PF03747(ADP_ribosyl_GH) | 4 | LEU A 74LEU A 69TYR A 148LEU A 146 | None | 0.91A | 1kt3A-2qtyA:undetectable | 1kt3A-2qtyA:19.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2wq9 | RETINOL-BINDINGPROTEIN 4 (Homo sapiens) |
PF00061(Lipocalin) | 6 | LEU A 37MET A 73MET A 88TYR A 90LEU A 97GLN A 98 | OLA A1179 (-3.4A)OLA A1179 ( 4.9A)OLA A1179 ( 3.8A)OLA A1179 (-3.7A)NoneNone | 0.64A | 1kt3A-2wq9A:25.6 | 1kt3A-2wq9A:93.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z3k | LEUCYL/PHENYLALANYL-TRNA-PROTEINTRANSFERASE (Escherichiacoli) |
PF03588(Leu_Phe_trans) | 4 | LEU A 6LEU A 57LEU A 3GLN A 5 | None | 1.07A | 1kt3A-2z3kA:undetectable | 1kt3A-2z3kA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zb3 | PROSTAGLANDINREDUCTASE 2 (Mus musculus) |
PF00107(ADH_zinc_N)PF16884(ADH_N_2) | 4 | LEU A 34LEU A 30LEU A 109GLN A 38 | None | 1.11A | 1kt3A-2zb3A:undetectable | 1kt3A-2zb3A:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zzr | UNSATURATEDGLUCURONYL HYDROLASE (Streptococcusagalactiae) |
PF07470(Glyco_hydro_88) | 4 | LEU A 177TYR A 204LEU A 271GLN A 268 | None | 1.10A | 1kt3A-2zzrA:undetectable | 1kt3A-2zzrA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cf4 | ACETYL-COADECARBOXYLASE/SYNTHASE ALPHA SUBUNIT (Methanosarcinabarkeri) |
PF03063(Prismane) | 4 | LEU A 388LEU A 245TYR A 261LEU A 381 | None | 0.99A | 1kt3A-3cf4A:undetectable | 1kt3A-3cf4A:12.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ebc | TYPE-2 RESTRICTIONENZYME HINCII (Haemophilusinfluenzae) |
PF09226(Endonuc-HincII) | 4 | LEU A 79LEU A 60TYR A 123LEU A 86 | None | 1.05A | 1kt3A-3ebcA:undetectable | 1kt3A-3ebcA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ez9 | PARA (Salmonellaenterica) |
PF13614(AAA_31) | 4 | LEU A 261TYR A 231LEU A 296GLN A 298 | None | 1.01A | 1kt3A-3ez9A:undetectable | 1kt3A-3ez9A:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fhn | PROTEIN TRANSPORTPROTEIN TIP20 (Saccharomycescerevisiae) |
PF04437(RINT1_TIP1) | 4 | LEU A 567MET A 458TYR A 455LEU A 574 | None | 0.94A | 1kt3A-3fhnA:undetectable | 1kt3A-3fhnA:13.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3fmz | RETINOL-BINDINGPROTEIN 4 (Homo sapiens) |
PF00061(Lipocalin) | 4 | LEU A 35LEU A 37MET A 88TYR A 90 | 2T1 A 184 (-4.0A)2T1 A 184 (-3.6A)2T1 A 184 (-3.1A)2T1 A 184 (-3.8A) | 0.38A | 1kt3A-3fmzA:26.1 | 1kt3A-3fmzA:92.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3fmz | RETINOL-BINDINGPROTEIN 4 (Homo sapiens) |
PF00061(Lipocalin) | 4 | LEU A 37MET A 88TYR A 90GLN A 98 | 2T1 A 184 (-3.6A)2T1 A 184 (-3.1A)2T1 A 184 (-3.8A)2T1 A 184 (-3.0A) | 0.79A | 1kt3A-3fmzA:26.1 | 1kt3A-3fmzA:92.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gkq | TERMINAL OXYGENASECOMPONENT OFCARBAZOLE1,9A-DIOXYGENASE (Sphingomonassp. KA1) |
PF00355(Rieske)PF11723(Aromatic_hydrox) | 4 | LEU A 327LEU A 195LEU A 281GLN A 283 | None | 0.96A | 1kt3A-3gkqA:undetectable | 1kt3A-3gkqA:17.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ihw | CENTG3 (Homo sapiens) |
PF00071(Ras) | 4 | LEU A 180LEU A 182MET A 193LEU A 222 | None | 1.09A | 1kt3A-3ihwA:undetectable | 1kt3A-3ihwA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k7y | ASPARTATEAMINOTRANSFERASE (Plasmodiumfalciparum) |
PF00155(Aminotran_1_2) | 4 | LEU A 80LEU A 84MET A 251LEU A 300 | None | 1.05A | 1kt3A-3k7yA:undetectable | 1kt3A-3k7yA:16.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lza | PUTATIVE SNOAL-LIKEPOLYKETIDE CYCLASE (Shewanelladenitrificans) |
PF12680(SnoaL_2) | 4 | LEU A 28LEU A 30MET A 99LEU A 129 | None | 1.05A | 1kt3A-3lzaA:undetectable | 1kt3A-3lzaA:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ne5 | CATION EFFLUX SYSTEMPROTEIN CUSA (Escherichiacoli) |
PF00873(ACR_tran) | 4 | LEU A 315TYR A 142LEU A 156GLN A 160 | None | 1.05A | 1kt3A-3ne5A:undetectable | 1kt3A-3ne5A:11.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nrn | UNCHARACTERIZEDPROTEIN PF1083 (Pyrococcusfuriosus) |
PF01593(Amino_oxidase) | 4 | LEU A 49LEU A 54TYR A 352GLN A 350 | None | 0.79A | 1kt3A-3nrnA:undetectable | 1kt3A-3nrnA:15.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o4y | CALCIUM-DEPENDENTPROTEIN KINASE 3 (Plasmodiumvivax) |
PF13499(EF-hand_7)PF13833(EF-hand_8) | 4 | LEU A 40LEU A 147MET A 171LEU A 33 | None | 1.04A | 1kt3A-3o4yA:undetectable | 1kt3A-3o4yA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3od1 | ATPPHOSPHORIBOSYLTRANSFERASE REGULATORYSUBUNIT (Bacillushalodurans) |
PF13393(tRNA-synt_His) | 4 | LEU A 171LEU A 266MET A 246LEU A 243 | None | 0.95A | 1kt3A-3od1A:undetectable | 1kt3A-3od1A:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pco | PHENYLALANYL-TRNASYNTHETASE, ALPHASUBUNIT (Escherichiacoli) |
PF01409(tRNA-synt_2d)PF02912(Phe_tRNA-synt_N) | 4 | LEU A 267MET A 304LEU A 312GLN A 200 | None | 1.11A | 1kt3A-3pcoA:undetectable | 1kt3A-3pcoA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qd9 | QSOX FROMTRYPANOSOMA BRUCEI(TBQSOX) (Trypanosomabrucei) |
PF00085(Thioredoxin)PF04777(Evr1_Alr) | 4 | LEU A 250LEU A 245MET A 227MET A 319 | None | 0.99A | 1kt3A-3qd9A:undetectable | 1kt3A-3qd9A:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r2x | HB36.3, DESIGNEDHEMAGGLUTININBINDING PROTEIN (syntheticconstruct) |
PF08958(DUF1871) | 4 | LEU C 13LEU C 15TYR C 43LEU C 79 | None | 1.11A | 1kt3A-3r2xC:undetectable | 1kt3A-3r2xC:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rg2 | ENTEROBACTINSYNTHASE COMPONENT E(ENTE),2,3-DIHYDRO-2,3-DIHYDROXYBENZOATESYNTHETASE,ISOCHROISMATASE(ENTB) (Escherichiacoli) |
PF00501(AMP-binding)PF00550(PP-binding)PF13193(AMP-binding_C) | 4 | LEU A 31LEU A 94TYR A 208LEU A 244 | None | 0.82A | 1kt3A-3rg2A:undetectable | 1kt3A-3rg2A:16.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rko | NADH-QUINONEOXIDOREDUCTASESUBUNIT JNADH-QUINONEOXIDOREDUCTASESUBUNIT LNADH-QUINONEOXIDOREDUCTASESUBUNIT N (Escherichiacoli;Escherichiacoli;Escherichiacoli) |
no annotationno annotationno annotation | 4 | LEU N 204LEU N 202TYR J 109LEU L 606 | None | 1.08A | 1kt3A-3rkoN:undetectable | 1kt3A-3rkoN:16.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rv6 | ISOCHORISMATESYNTHASE/ISOCHORISMATE-PYRUVATE LYASEMBTI (Mycobacteriumtuberculosis) |
PF00425(Chorismate_bind) | 4 | LEU A 99LEU A 392MET A 350LEU A 92 | None | 0.90A | 1kt3A-3rv6A:undetectable | 1kt3A-3rv6A:17.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3son | HYPOTHETICAL NUDIXHYDROLASE (Listeriamonocytogenes) |
PF00293(NUDIX) | 4 | LEU A 133LEU A 68MET A 145LEU A 140 | None | 1.11A | 1kt3A-3sonA:undetectable | 1kt3A-3sonA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sun | DNA POLYMERASE (Escherichiavirus RB69) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 4 | LEU A 605MET A 408MET A 683LEU A 651 | None | 0.95A | 1kt3A-3sunA:undetectable | 1kt3A-3sunA:12.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tef | IRON(III) ABCTRANSPORTER,PERIPLASMICIRON-COMPOUND-BINDING PROTEIN (Vibrio cholerae) |
PF01497(Peripla_BP_2) | 4 | LEU A 210LEU A 265TYR A 256LEU A 218 | None | 1.09A | 1kt3A-3tefA:undetectable | 1kt3A-3tefA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u1d | UNCHARACTERIZEDPROTEIN (Halomicrobiummukohataei) |
PF12840(HTH_20) | 4 | LEU A 29MET A 121TYR A 118LEU A 36 | NoneNoneNonePEG A 152 (-4.8A) | 1.01A | 1kt3A-3u1dA:undetectable | 1kt3A-3u1dA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v0t | PERAKINE REDUCTASE (Rauvolfiaserpentina) |
PF00248(Aldo_ket_red) | 4 | LEU A 302TYR A 179LEU A 268GLN A 270 | None | 1.06A | 1kt3A-3v0tA:undetectable | 1kt3A-3v0tA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v8d | CHOLESTEROL7-ALPHA-MONOOXYGENASE (Homo sapiens) |
PF00067(p450) | 4 | LEU A 469MET A 171LEU A 298GLN A 300 | None | 0.89A | 1kt3A-3v8dA:undetectable | 1kt3A-3v8dA:16.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wad | GLYCOSYLTRANSFERASE (Streptomyceshalstedii) |
PF06722(DUF1205) | 4 | LEU A 77LEU A 79MET A 106GLN A 98 | None | 1.11A | 1kt3A-3wadA:undetectable | 1kt3A-3wadA:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zs7 | PYRIDOXAL KINASE (Trypanosomabrucei) |
PF08543(Phos_pyr_kin) | 4 | LEU A 98LEU A 7MET A 65MET A 56 | None | 0.99A | 1kt3A-3zs7A:undetectable | 1kt3A-3zs7A:17.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g4p | AMINO ACID ABCTRANSPORTER, AMINOACID-BINDING/PERMEASE PROTEIN (Enterococcusfaecalis) |
PF00497(SBP_bac_3) | 4 | LEU A 111LEU A 113TYR A 152LEU A 145 | None | 1.10A | 1kt3A-4g4pA:undetectable | 1kt3A-4g4pA:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gou | EHRGS-RHOGEF (Entamoebahistolytica) |
PF00615(RGS)PF00621(RhoGEF) | 4 | LEU A 147LEU A 28LEU A 149GLN A 151 | None | 1.03A | 1kt3A-4gouA:undetectable | 1kt3A-4gouA:15.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j3b | M1 FAMILYAMINOPEPTIDASE (Plasmodiumfalciparum) |
PF01433(Peptidase_M1)PF11940(DUF3458)PF17432(DUF3458_C) | 4 | LEU A 276LEU A 244MET A 233MET A 335 | None | 1.08A | 1kt3A-4j3bA:undetectable | 1kt3A-4j3bA:11.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k17 | LEUCINE-RICHREPEAT-CONTAININGPROTEIN 16A (Mus musculus) |
PF13516(LRR_6) | 4 | LEU A 379LEU A 372TYR A 358LEU A 386 | None | 1.00A | 1kt3A-4k17A:undetectable | 1kt3A-4k17A:13.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4knh | NUP192P (Chaetomiumthermophilum) |
PF11894(Nup192) | 4 | LEU A 497MET A 515TYR A 475LEU A 468 | None | 1.00A | 1kt3A-4knhA:undetectable | 1kt3A-4knhA:11.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kto | ISOVALERYL-COADEHYDROGENASE (Sinorhizobiummeliloti) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | LEU A 244TYR A 174LEU A 98GLN A 102 | None | 1.03A | 1kt3A-4ktoA:undetectable | 1kt3A-4ktoA:18.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m2g | L-ARGININEBETA-HYDROXYLASE (Streptomyceslavendulae) |
PF02668(TauD) | 4 | LEU A 254LEU A 185TYR A 244LEU A 198 | None | 1.06A | 1kt3A-4m2gA:undetectable | 1kt3A-4m2gA:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m7e | PROTEINBRASSINOSTEROIDINSENSITIVE 1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF12799(LRR_4)PF13516(LRR_6)PF13855(LRR_8) | 4 | LEU A 469LEU A 442TYR A 422LEU A 447 | None | 1.02A | 1kt3A-4m7eA:undetectable | 1kt3A-4m7eA:12.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mkv | RIBULOSEBISPHOSPHATECARBOXYLASE LARGECHAIN (Pisum sativum) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 4 | LEU A 400MET A 266TYR A 239LEU A 197 | None | 1.04A | 1kt3A-4mkvA:undetectable | 1kt3A-4mkvA:15.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n8y | PUTATIVE TRAP-TYPEC4-DICARBOXYLATETRANSPORT SYSTEM,BINDING PERIPLASMICPROTEIN (DCTPSUBUNIT) (Bradyrhizobiumsp. BTAi1) |
PF03480(DctP) | 4 | LEU A 101LEU A 172TYR A 303LEU A 312 | None | 1.03A | 1kt3A-4n8yA:undetectable | 1kt3A-4n8yA:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4noo | VGRG PROTEIN (Vibrio cholerae) |
no annotation | 4 | LEU A 949LEU A 954LEU A 935GLN A 914 | None | 1.02A | 1kt3A-4nooA:undetectable | 1kt3A-4nooA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pxd | ALLANTOATEAMIDOHYDROLASE (Escherichiacoli) |
PF01546(Peptidase_M20) | 4 | LEU A 341LEU A 334LEU A 404GLN A 406 | None | 1.06A | 1kt3A-4pxdA:undetectable | 1kt3A-4pxdA:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rbr | HTH-TYPETRANSCRIPTIONALREGULATOR ROT (Staphylococcusaureus) |
PF01047(MarR) | 4 | LEU A 102LEU A 109MET A 36LEU A 79 | None | 1.07A | 1kt3A-4rbrA:undetectable | 1kt3A-4rbrA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ryk | LMO0325 PROTEIN (Listeriamonocytogenes) |
PF01381(HTH_3) | 4 | LEU A 224MET A 180TYR A 184LEU A 200 | None | 1.11A | 1kt3A-4rykA:undetectable | 1kt3A-4rykA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u48 | PUTATIVE INNERMEMBRANE LIPOPROTEIN (Salmonellaenterica) |
PF00207(A2M)PF01835(A2M_N)PF07703(A2M_N_2)PF10569(Thiol-ester_cl)PF11974(MG1) | 4 | LEU A 585LEU A 555TYR A 504LEU A 481 | None | 1.01A | 1kt3A-4u48A:undetectable | 1kt3A-4u48A:8.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wfw | GENERAL SECRETIONPATHWAY PROTEIN B (Dickeyadadantii) |
PF16537(T2SSB) | 4 | LEU A 187LEU A 184TYR A 129LEU A 148 | None | 1.06A | 1kt3A-4wfwA:undetectable | 1kt3A-4wfwA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wz9 | AGAP004809-PA (Anophelesgambiae) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 4 | LEU A 466LEU A 475MET A 402LEU A 459 | None | 1.03A | 1kt3A-4wz9A:undetectable | 1kt3A-4wz9A:11.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wz9 | AGAP004809-PA (Anophelesgambiae) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 4 | LEU A 466LEU A 475TYR A 398LEU A 459 | None | 0.93A | 1kt3A-4wz9A:undetectable | 1kt3A-4wz9A:11.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a22 | VESICULAR STOMATITISVIRUS L POLYMERASE (Vesicularstomatitisvirus) |
PF00946(Mononeg_RNA_pol)PF14314(Methyltrans_Mon)PF14318(Mononeg_mRNAcap) | 4 | LEU A 693LEU A 691TYR A 606GLN A 716 | None | 1.11A | 1kt3A-5a22A:undetectable | 1kt3A-5a22A:5.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5az4 | FLAGELLAR HOOKSUBUNIT PROTEIN (Campylobacterjejuni) |
PF07196(Flagellin_IN)PF07559(FlaE) | 4 | LEU A 509MET A 575TYR A 259LEU A 492 | None | 1.08A | 1kt3A-5az4A:undetectable | 1kt3A-5az4A:15.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d0f | UNCHARACTERIZEDPROTEIN ([Candida]glabrata) |
PF06202(GDE_C)PF14699(hGDE_N)PF14701(hDGE_amylase)PF14702(hGDE_central) | 4 | LEU A 891LEU A 889TYR A 896LEU A 898 | None | 1.04A | 1kt3A-5d0fA:undetectable | 1kt3A-5d0fA:8.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5du9 | CDA PEPTIDESYNTHETASE I (Streptomycescoelicolor) |
PF00668(Condensation) | 4 | LEU A 314LEU A 312TYR A 215LEU A 339 | None | 1.06A | 1kt3A-5du9A:undetectable | 1kt3A-5du9A:17.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hb4 | NUP192,NUCLEOPORINNUP192 (Chaetomiumthermophilum) |
PF11894(Nup192) | 4 | LEU B 497MET B 515TYR B 475LEU B 468 | None | 0.98A | 1kt3A-5hb4B:undetectable | 1kt3A-5hb4B:7.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ir6 | BD-TYPE QUINOLOXIDASE SUBUNIT I (Geobacillusstearothermophilus) |
PF01654(Cyt_bd_oxida_I) | 4 | LEU A 365MET A 224MET A 34LEU A 359 | None | 0.92A | 1kt3A-5ir6A:undetectable | 1kt3A-5ir6A:16.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j90 | RAGB/SUSD DOMAINPROTEIN (Flavobacteriumjohnsoniae) |
PF12741(SusD-like) | 4 | LEU A 224LEU A 140TYR A 210LEU A 347 | None | 0.99A | 1kt3A-5j90A:undetectable | 1kt3A-5j90A:15.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l46 | DIMETHYLGLYCINEDEHYDROGENASE,MITOCHONDRIAL (Homo sapiens) |
PF01266(DAO)PF01571(GCV_T)PF08669(GCV_T_C)PF16350(FAO_M) | 4 | LEU A 604LEU A 581MET A 570TYR A 578 | None | 1.10A | 1kt3A-5l46A:undetectable | 1kt3A-5l46A:13.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lpy | PROTEINBRASSINOSTEROIDINSENSITIVE 1 (Arabidopsisthaliana) |
PF00069(Pkinase) | 4 | LEU A 871LEU A 954MET A 928LEU A 868 | None | 1.03A | 1kt3A-5lpyA:undetectable | 1kt3A-5lpyA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lpz | PROTEINBRASSINOSTEROIDINSENSITIVE 1 (Arabidopsisthaliana) |
PF00069(Pkinase) | 4 | LEU A 871LEU A 954MET A 928LEU A 868 | None | 1.03A | 1kt3A-5lpzA:undetectable | 1kt3A-5lpzA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lxz | SECRETED PROTEIN (Streptomyceslividans) |
PF07646(Kelch_2)PF09118(DUF1929) | 4 | LEU B 344LEU B 397LEU B 619GLN B 621 | None | 1.02A | 1kt3A-5lxzB:undetectable | 1kt3A-5lxzB:15.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m3q | EUKARYOTICTRANSLATIONINITIATION FACTOR 6 (Chaetomiumthermophilum) |
PF01912(eIF-6) | 4 | LEU A 176LEU A 181MET A 152GLN A 140 | None | 1.09A | 1kt3A-5m3qA:undetectable | 1kt3A-5m3qA:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mgy | FAD:PROTEIN FMNTRANSFERASE (Pseudomonasstutzeri) |
no annotation | 4 | LEU H 72LEU H 192MET H 105LEU H 79 | None | 1.10A | 1kt3A-5mgyH:undetectable | 1kt3A-5mgyH:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nfj | MITOCHONDRIALRIBONUCLEASE PPROTEIN 1 (Homo sapiens) |
no annotation | 4 | LEU A 271LEU A 227MET A 209LEU A 248 | None | 1.10A | 1kt3A-5nfjA:undetectable | 1kt3A-5nfjA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tf0 | GLYCOSYL HYDROLASEFAMILY 3 N-TERMINALDOMAIN PROTEIN (Bacteroidesintestinalis) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | LEU A 107LEU A 84LEU A 96GLN A 94 | None | 1.10A | 1kt3A-5tf0A:undetectable | 1kt3A-5tf0A:13.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vfr | PROTEASOME SUBUNITALPHA TYPE-4 (Homo sapiens) |
no annotation | 4 | LEU I 99MET I 72LEU I 92GLN I 95 | None | 0.85A | 1kt3A-5vfrI:undetectable | 1kt3A-5vfrI:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vhv | ALKYLPURINE DNAGLYCOSYLASE ALKC (Pseudomonasfluorescens) |
no annotation | 4 | LEU A 162LEU A 128MET A 139LEU A 153 | None | 0.85A | 1kt3A-5vhvA:undetectable | 1kt3A-5vhvA:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x1e | ICMSICMWICMO (DOTL) (Legionellapneumophila;Legionellapneumophila;Legionellapneumophila) |
PF12608(T4bSS_IcmS)no annotationno annotation | 4 | LEU B 131LEU A 87MET C 712LEU C 733 | None | 1.06A | 1kt3A-5x1eB:undetectable | 1kt3A-5x1eB:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cty | DIHYDROOROTASE (Yersinia pestis) |
no annotation | 4 | LEU A 162LEU A 104TYR A 124LEU A 172 | NoneKCX A 103 ( 4.5A)NoneNone | 1.10A | 1kt3A-6ctyA:undetectable | 1kt3A-6ctyA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6du8 | - (-) |
no annotation | 4 | LEU A 294LEU A 288LEU A 200GLN A 202 | None | 0.90A | 1kt3A-6du8A:undetectable | 1kt3A-6du8A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ftl | RIBULOSEBISPHOSPHATECARBOXYLASE LARGECHAIN (Skeletonemamarinoi) |
no annotation | 4 | LEU A 403MET A 270TYR A 243LEU A 201 | HLU A 174 ( 4.8A)KCX A 205 ( 3.6A)KCX A 205 ( 4.1A)HLU A 174 ( 3.6A) | 1.01A | 1kt3A-6ftlA:undetectable | 1kt3A-6ftlA:undetectable |