SIMILAR PATTERNS OF AMINO ACIDS FOR 1KT3_A_RTLA184

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)


(Cupriavidus
necator)
PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N)
4 LEU A 402
MET A 269
TYR A 242
LEU A 200
None
1.03A 1kt3A-1bxnA:
0.0
1kt3A-1bxnA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cg4 PROTEIN
(ADENYLOSUCCINATE
SYNTHETASE)


(Escherichia
coli)
PF00709
(Adenylsucc_synt)
4 LEU A 146
LEU A 151
MET A  80
LEU A 187
None
1.09A 1kt3A-1cg4A:
0.0
1kt3A-1cg4A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ddz CARBONIC ANHYDRASE

(Porphyridium
purpureum)
PF00484
(Pro_CA)
4 LEU A 222
LEU A 227
TYR A 448
GLN A 443
None
0.97A 1kt3A-1ddzA:
0.0
1kt3A-1ddzA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE


(Thermotoga
maritima)
PF00128
(Alpha-amylase)
PF09083
(DUF1923)
4 LEU A  25
LEU A 125
TYR A  97
LEU A 543
None
1.10A 1kt3A-1gjuA:
undetectable
1kt3A-1gjuA:
14.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1iiu PLASMA
RETINOL-BINDING
PROTEIN


(Gallus gallus)
PF00061
(Lipocalin)
7 LEU A  35
LEU A  37
MET A  73
MET A  88
TYR A  90
LEU A  97
GLN A  98
RTL  A 176 (-4.5A)
RTL  A 176 ( 4.5A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-3.4A)
RTL  A 176 ( 4.0A)
RTL  A 176 (-4.0A)
RTL  A 176 (-3.8A)
0.40A 1kt3A-1iiuA:
28.1
1kt3A-1iiuA:
79.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT


(Galdieria
partita)
PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N)
4 LEU A 400
MET A 266
TYR A 239
LEU A 197
None
1.02A 1kt3A-1iwaA:
undetectable
1kt3A-1iwaA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mhz METHANE
MONOOXYGENASE
HYDROXYLASE


(Methylosinus
trichosporium)
PF02332
(Phenol_Hydrox)
4 LEU D 448
TYR D 464
LEU D 458
GLN D 456
None
1.06A 1kt3A-1mhzD:
0.0
1kt3A-1mhzD:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pv5 HYPOTHETICAL PROTEIN
YWQG


(Bacillus
subtilis)
PF09234
(DUF1963)
4 MET A  60
TYR A  86
LEU A  83
GLN A  84
None
1.07A 1kt3A-1pv5A:
0.0
1kt3A-1pv5A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)


(Synechococcus
elongatus)
PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N)
4 LEU A 400
MET A 266
TYR A 239
LEU A 197
None
1.07A 1kt3A-1rblA:
0.0
1kt3A-1rblA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1su3 INTERSTITIAL
COLLAGENASE


(Homo sapiens)
PF00045
(Hemopexin)
PF00413
(Peptidase_M10)
PF01471
(PG_binding_1)
4 LEU A  73
LEU A  64
TYR A  37
LEU A  84
None
1.09A 1kt3A-1su3A:
undetectable
1kt3A-1su3A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1svd RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT


(Halothiobacillus
neapolitanus)
PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N)
4 LEU A 393
MET A 259
TYR A 232
LEU A 190
None
1.06A 1kt3A-1svdA:
undetectable
1kt3A-1svdA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u84 HYPOTHETICAL PROTEIN

(Geobacillus
stearothermophilus)
PF08958
(DUF1871)
4 LEU A   9
LEU A  11
TYR A  39
LEU A  75
None
0.94A 1kt3A-1u84A:
undetectable
1kt3A-1u84A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9k RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE C


(Escherichia
coli)
PF00849
(PseudoU_synth_2)
4 LEU A 160
LEU A 152
MET A 172
LEU A 167
None
1.09A 1kt3A-1v9kA:
undetectable
1kt3A-1v9kA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vma CELL DIVISION
PROTEIN FTSY


(Thermotoga
maritima)
PF00448
(SRP54)
PF02881
(SRP54_N)
4 LEU A  76
LEU A  71
TYR A  55
LEU A 257
None
1.05A 1kt3A-1vmaA:
undetectable
1kt3A-1vmaA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x9s DNA POLYMERASE

(Escherichia
virus T7)
PF00476
(DNA_pol_A)
4 LEU A 479
LEU A 481
TYR A 530
LEU A 614
None
0.97A 1kt3A-1x9sA:
undetectable
1kt3A-1x9sA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
ORPHAN NUCLEAR
RECEPTOR NR1I3


(Homo sapiens;
Mus musculus)
PF00104
(Hormone_recep)
PF00104
(Hormone_recep)
4 LEU E 300
LEU E 302
MET E 323
LEU A 420
None
1.06A 1kt3A-1xlsE:
undetectable
1kt3A-1xlsE:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xvi PUTATIVE
MANNOSYL-3-PHOSPHOGL
YCERATE PHOSPHATASE


(Escherichia
coli)
PF08282
(Hydrolase_3)
4 LEU A  14
LEU A  19
MET A  54
LEU A  45
None
1.01A 1kt3A-1xviA:
undetectable
1kt3A-1xviA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y7e PROBABLE M18-FAMILY
AMINOPEPTIDASE 1


(Borreliella
burgdorferi)
PF02127
(Peptidase_M18)
4 LEU A  10
TYR A 446
LEU A  19
GLN A  17
None
0.96A 1kt3A-1y7eA:
undetectable
1kt3A-1y7eA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yp0 NUCLEAR RECEPTOR
SUBFAMILY 5, GROUP
A, MEMBER 1


(Mus musculus)
PF00104
(Hormone_recep)
4 LEU A 229
MET A 285
LEU A 231
GLN A 233
None
0.99A 1kt3A-1yp0A:
undetectable
1kt3A-1yp0A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a3l AMP DEAMINASE

(Arabidopsis
thaliana)
PF00962
(A_deaminase)
4 LEU A 729
LEU A 355
LEU A 697
GLN A 699
None
0.93A 1kt3A-2a3lA:
undetectable
1kt3A-2a3lA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a8v RNA BINDING DOMAIN
OF RHO TRANSCRIPTION
TERMINATION FACTOR


(Escherichia
coli)
PF07497
(Rho_RNA_bind)
PF07498
(Rho_N)
5 LEU A  23
LEU A  17
MET A   1
LEU A  39
GLN A  41
None
1.28A 1kt3A-2a8vA:
undetectable
1kt3A-2a8vA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2abj BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE,
CYTOSOLIC


(Homo sapiens)
PF01063
(Aminotran_4)
4 LEU A  96
MET A 115
LEU A 135
GLN A 140
None
1.10A 1kt3A-2abjA:
undetectable
1kt3A-2abjA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f6k METAL-DEPENDENT
HYDROLASE


(Lactobacillus
plantarum)
PF04909
(Amidohydro_2)
4 LEU A 188
MET A 233
TYR A 230
LEU A 210
None
0.99A 1kt3A-2f6kA:
undetectable
1kt3A-2f6kA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gie TYPE II RESTRICTION
ENZYME HINCII


(Haemophilus
influenzae)
PF09226
(Endonuc-HincII)
4 LEU A  79
LEU A  60
TYR A 123
LEU A  86
None
1.10A 1kt3A-2gieA:
undetectable
1kt3A-2gieA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h3g BIOSYNTHETIC PROTEIN

(Bacillus
anthracis)
PF03309
(Pan_kinase)
4 LEU X  47
LEU X  42
MET X  28
LEU X  14
None
1.05A 1kt3A-2h3gX:
undetectable
1kt3A-2h3gX:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n8o BACTERIOCIN AUREOCIN
A53


(Staphylococcus
aureus)
PF11758
(Bacteriocin_IIi)
4 LEU A  38
LEU A  45
TYR A  13
LEU A   7
None
1.06A 1kt3A-2n8oA:
undetectable
1kt3A-2n8oA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p1n SKP1-LIKE PROTEIN 1A

(Arabidopsis
thaliana)
PF01466
(Skp1)
PF03931
(Skp1_POZ)
4 LEU A 114
LEU A 116
MET A  91
LEU A 101
None
1.09A 1kt3A-2p1nA:
undetectable
1kt3A-2p1nA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4f SIMILAR TO SP|P32453
SACCHAROMYCES
CEREVISIAE YNL315C
ATP11


([Candida]
glabrata)
PF06644
(ATP11)
4 LEU A 158
MET A 146
TYR A 257
LEU A 273
None
1.09A 1kt3A-2p4fA:
undetectable
1kt3A-2p4fA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qty POLY(ADP-RIBOSE)
GLYCOHYDROLASE ARH3


(Mus musculus)
PF03747
(ADP_ribosyl_GH)
4 LEU A  74
LEU A  69
TYR A 148
LEU A 146
None
0.91A 1kt3A-2qtyA:
undetectable
1kt3A-2qtyA:
19.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2wq9 RETINOL-BINDING
PROTEIN 4


(Homo sapiens)
PF00061
(Lipocalin)
6 LEU A  37
MET A  73
MET A  88
TYR A  90
LEU A  97
GLN A  98
OLA  A1179 (-3.4A)
OLA  A1179 ( 4.9A)
OLA  A1179 ( 3.8A)
OLA  A1179 (-3.7A)
None
None
0.64A 1kt3A-2wq9A:
25.6
1kt3A-2wq9A:
93.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z3k LEUCYL/PHENYLALANYL-
TRNA-PROTEIN
TRANSFERASE


(Escherichia
coli)
PF03588
(Leu_Phe_trans)
4 LEU A   6
LEU A  57
LEU A   3
GLN A   5
None
1.07A 1kt3A-2z3kA:
undetectable
1kt3A-2z3kA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zb3 PROSTAGLANDIN
REDUCTASE 2


(Mus musculus)
PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2)
4 LEU A  34
LEU A  30
LEU A 109
GLN A  38
None
1.11A 1kt3A-2zb3A:
undetectable
1kt3A-2zb3A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zzr UNSATURATED
GLUCURONYL HYDROLASE


(Streptococcus
agalactiae)
PF07470
(Glyco_hydro_88)
4 LEU A 177
TYR A 204
LEU A 271
GLN A 268
None
1.10A 1kt3A-2zzrA:
undetectable
1kt3A-2zzrA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cf4 ACETYL-COA
DECARBOXYLASE/SYNTHA
SE ALPHA SUBUNIT


(Methanosarcina
barkeri)
PF03063
(Prismane)
4 LEU A 388
LEU A 245
TYR A 261
LEU A 381
None
0.99A 1kt3A-3cf4A:
undetectable
1kt3A-3cf4A:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ebc TYPE-2 RESTRICTION
ENZYME HINCII


(Haemophilus
influenzae)
PF09226
(Endonuc-HincII)
4 LEU A  79
LEU A  60
TYR A 123
LEU A  86
None
1.05A 1kt3A-3ebcA:
undetectable
1kt3A-3ebcA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ez9 PARA

(Salmonella
enterica)
PF13614
(AAA_31)
4 LEU A 261
TYR A 231
LEU A 296
GLN A 298
None
1.01A 1kt3A-3ez9A:
undetectable
1kt3A-3ez9A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fhn PROTEIN TRANSPORT
PROTEIN TIP20


(Saccharomyces
cerevisiae)
PF04437
(RINT1_TIP1)
4 LEU A 567
MET A 458
TYR A 455
LEU A 574
None
0.94A 1kt3A-3fhnA:
undetectable
1kt3A-3fhnA:
13.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3fmz RETINOL-BINDING
PROTEIN 4


(Homo sapiens)
PF00061
(Lipocalin)
4 LEU A  35
LEU A  37
MET A  88
TYR A  90
2T1  A 184 (-4.0A)
2T1  A 184 (-3.6A)
2T1  A 184 (-3.1A)
2T1  A 184 (-3.8A)
0.38A 1kt3A-3fmzA:
26.1
1kt3A-3fmzA:
92.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3fmz RETINOL-BINDING
PROTEIN 4


(Homo sapiens)
PF00061
(Lipocalin)
4 LEU A  37
MET A  88
TYR A  90
GLN A  98
2T1  A 184 (-3.6A)
2T1  A 184 (-3.1A)
2T1  A 184 (-3.8A)
2T1  A 184 (-3.0A)
0.79A 1kt3A-3fmzA:
26.1
1kt3A-3fmzA:
92.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gkq TERMINAL OXYGENASE
COMPONENT OF
CARBAZOLE
1,9A-DIOXYGENASE


(Sphingomonas
sp. KA1)
PF00355
(Rieske)
PF11723
(Aromatic_hydrox)
4 LEU A 327
LEU A 195
LEU A 281
GLN A 283
None
0.96A 1kt3A-3gkqA:
undetectable
1kt3A-3gkqA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihw CENTG3

(Homo sapiens)
PF00071
(Ras)
4 LEU A 180
LEU A 182
MET A 193
LEU A 222
None
1.09A 1kt3A-3ihwA:
undetectable
1kt3A-3ihwA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k7y ASPARTATE
AMINOTRANSFERASE


(Plasmodium
falciparum)
PF00155
(Aminotran_1_2)
4 LEU A  80
LEU A  84
MET A 251
LEU A 300
None
1.05A 1kt3A-3k7yA:
undetectable
1kt3A-3k7yA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lza PUTATIVE SNOAL-LIKE
POLYKETIDE CYCLASE


(Shewanella
denitrificans)
PF12680
(SnoaL_2)
4 LEU A  28
LEU A  30
MET A  99
LEU A 129
None
1.05A 1kt3A-3lzaA:
undetectable
1kt3A-3lzaA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ne5 CATION EFFLUX SYSTEM
PROTEIN CUSA


(Escherichia
coli)
PF00873
(ACR_tran)
4 LEU A 315
TYR A 142
LEU A 156
GLN A 160
None
1.05A 1kt3A-3ne5A:
undetectable
1kt3A-3ne5A:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nrn UNCHARACTERIZED
PROTEIN PF1083


(Pyrococcus
furiosus)
PF01593
(Amino_oxidase)
4 LEU A  49
LEU A  54
TYR A 352
GLN A 350
None
0.79A 1kt3A-3nrnA:
undetectable
1kt3A-3nrnA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o4y CALCIUM-DEPENDENT
PROTEIN KINASE 3


(Plasmodium
vivax)
PF13499
(EF-hand_7)
PF13833
(EF-hand_8)
4 LEU A  40
LEU A 147
MET A 171
LEU A  33
None
1.04A 1kt3A-3o4yA:
undetectable
1kt3A-3o4yA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3od1 ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT


(Bacillus
halodurans)
PF13393
(tRNA-synt_His)
4 LEU A 171
LEU A 266
MET A 246
LEU A 243
None
0.95A 1kt3A-3od1A:
undetectable
1kt3A-3od1A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT


(Escherichia
coli)
PF01409
(tRNA-synt_2d)
PF02912
(Phe_tRNA-synt_N)
4 LEU A 267
MET A 304
LEU A 312
GLN A 200
None
1.11A 1kt3A-3pcoA:
undetectable
1kt3A-3pcoA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)


(Trypanosoma
brucei)
PF00085
(Thioredoxin)
PF04777
(Evr1_Alr)
4 LEU A 250
LEU A 245
MET A 227
MET A 319
None
0.99A 1kt3A-3qd9A:
undetectable
1kt3A-3qd9A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r2x HB36.3, DESIGNED
HEMAGGLUTININ
BINDING PROTEIN


(synthetic
construct)
PF08958
(DUF1871)
4 LEU C  13
LEU C  15
TYR C  43
LEU C  79
None
1.11A 1kt3A-3r2xC:
undetectable
1kt3A-3r2xC:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rg2 ENTEROBACTIN
SYNTHASE COMPONENT E
(ENTE),
2,3-DIHYDRO-2,3-DIHY
DROXYBENZOATE
SYNTHETASE,
ISOCHROISMATASE
(ENTB)


(Escherichia
coli)
PF00501
(AMP-binding)
PF00550
(PP-binding)
PF13193
(AMP-binding_C)
4 LEU A  31
LEU A  94
TYR A 208
LEU A 244
None
0.82A 1kt3A-3rg2A:
undetectable
1kt3A-3rg2A:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rko NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT J
NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT L
NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT N


(Escherichia
coli;
Escherichia
coli;
Escherichia
coli)
no annotation
no annotation
no annotation
4 LEU N 204
LEU N 202
TYR J 109
LEU L 606
None
1.08A 1kt3A-3rkoN:
undetectable
1kt3A-3rkoN:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rv6 ISOCHORISMATE
SYNTHASE/ISOCHORISMA
TE-PYRUVATE LYASE
MBTI


(Mycobacterium
tuberculosis)
PF00425
(Chorismate_bind)
4 LEU A  99
LEU A 392
MET A 350
LEU A  92
None
0.90A 1kt3A-3rv6A:
undetectable
1kt3A-3rv6A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3son HYPOTHETICAL NUDIX
HYDROLASE


(Listeria
monocytogenes)
PF00293
(NUDIX)
4 LEU A 133
LEU A  68
MET A 145
LEU A 140
None
1.11A 1kt3A-3sonA:
undetectable
1kt3A-3sonA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sun DNA POLYMERASE

(Escherichia
virus RB69)
PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1)
4 LEU A 605
MET A 408
MET A 683
LEU A 651
None
0.95A 1kt3A-3sunA:
undetectable
1kt3A-3sunA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tef IRON(III) ABC
TRANSPORTER,
PERIPLASMIC
IRON-COMPOUND-BINDIN
G PROTEIN


(Vibrio cholerae)
PF01497
(Peripla_BP_2)
4 LEU A 210
LEU A 265
TYR A 256
LEU A 218
None
1.09A 1kt3A-3tefA:
undetectable
1kt3A-3tefA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u1d UNCHARACTERIZED
PROTEIN


(Halomicrobium
mukohataei)
PF12840
(HTH_20)
4 LEU A  29
MET A 121
TYR A 118
LEU A  36
None
None
None
PEG  A 152 (-4.8A)
1.01A 1kt3A-3u1dA:
undetectable
1kt3A-3u1dA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v0t PERAKINE REDUCTASE

(Rauvolfia
serpentina)
PF00248
(Aldo_ket_red)
4 LEU A 302
TYR A 179
LEU A 268
GLN A 270
None
1.06A 1kt3A-3v0tA:
undetectable
1kt3A-3v0tA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v8d CHOLESTEROL
7-ALPHA-MONOOXYGENAS
E


(Homo sapiens)
PF00067
(p450)
4 LEU A 469
MET A 171
LEU A 298
GLN A 300
None
0.89A 1kt3A-3v8dA:
undetectable
1kt3A-3v8dA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wad GLYCOSYLTRANSFERASE

(Streptomyces
halstedii)
PF06722
(DUF1205)
4 LEU A  77
LEU A  79
MET A 106
GLN A  98
None
1.11A 1kt3A-3wadA:
undetectable
1kt3A-3wadA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zs7 PYRIDOXAL KINASE

(Trypanosoma
brucei)
PF08543
(Phos_pyr_kin)
4 LEU A  98
LEU A   7
MET A  65
MET A  56
None
0.99A 1kt3A-3zs7A:
undetectable
1kt3A-3zs7A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g4p AMINO ACID ABC
TRANSPORTER, AMINO
ACID-BINDING/PERMEAS
E PROTEIN


(Enterococcus
faecalis)
PF00497
(SBP_bac_3)
4 LEU A 111
LEU A 113
TYR A 152
LEU A 145
None
1.10A 1kt3A-4g4pA:
undetectable
1kt3A-4g4pA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gou EHRGS-RHOGEF

(Entamoeba
histolytica)
PF00615
(RGS)
PF00621
(RhoGEF)
4 LEU A 147
LEU A  28
LEU A 149
GLN A 151
None
1.03A 1kt3A-4gouA:
undetectable
1kt3A-4gouA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j3b M1 FAMILY
AMINOPEPTIDASE


(Plasmodium
falciparum)
PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C)
4 LEU A 276
LEU A 244
MET A 233
MET A 335
None
1.08A 1kt3A-4j3bA:
undetectable
1kt3A-4j3bA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A


(Mus musculus)
PF13516
(LRR_6)
4 LEU A 379
LEU A 372
TYR A 358
LEU A 386
None
1.00A 1kt3A-4k17A:
undetectable
1kt3A-4k17A:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4knh NUP192P

(Chaetomium
thermophilum)
PF11894
(Nup192)
4 LEU A 497
MET A 515
TYR A 475
LEU A 468
None
1.00A 1kt3A-4knhA:
undetectable
1kt3A-4knhA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kto ISOVALERYL-COA
DEHYDROGENASE


(Sinorhizobium
meliloti)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
4 LEU A 244
TYR A 174
LEU A  98
GLN A 102
None
1.03A 1kt3A-4ktoA:
undetectable
1kt3A-4ktoA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m2g L-ARGININE
BETA-HYDROXYLASE


(Streptomyces
lavendulae)
PF02668
(TauD)
4 LEU A 254
LEU A 185
TYR A 244
LEU A 198
None
1.06A 1kt3A-4m2gA:
undetectable
1kt3A-4m2gA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m7e PROTEIN
BRASSINOSTEROID
INSENSITIVE 1


(Arabidopsis
thaliana)
PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF12799
(LRR_4)
PF13516
(LRR_6)
PF13855
(LRR_8)
4 LEU A 469
LEU A 442
TYR A 422
LEU A 447
None
1.02A 1kt3A-4m7eA:
undetectable
1kt3A-4m7eA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN


(Pisum sativum)
PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N)
4 LEU A 400
MET A 266
TYR A 239
LEU A 197
None
1.04A 1kt3A-4mkvA:
undetectable
1kt3A-4mkvA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n8y PUTATIVE TRAP-TYPE
C4-DICARBOXYLATE
TRANSPORT SYSTEM,
BINDING PERIPLASMIC
PROTEIN (DCTP
SUBUNIT)


(Bradyrhizobium
sp. BTAi1)
PF03480
(DctP)
4 LEU A 101
LEU A 172
TYR A 303
LEU A 312
None
1.03A 1kt3A-4n8yA:
undetectable
1kt3A-4n8yA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4noo VGRG PROTEIN

(Vibrio cholerae)
no annotation 4 LEU A 949
LEU A 954
LEU A 935
GLN A 914
None
1.02A 1kt3A-4nooA:
undetectable
1kt3A-4nooA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pxd ALLANTOATE
AMIDOHYDROLASE


(Escherichia
coli)
PF01546
(Peptidase_M20)
4 LEU A 341
LEU A 334
LEU A 404
GLN A 406
None
1.06A 1kt3A-4pxdA:
undetectable
1kt3A-4pxdA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rbr HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ROT


(Staphylococcus
aureus)
PF01047
(MarR)
4 LEU A 102
LEU A 109
MET A  36
LEU A  79
None
1.07A 1kt3A-4rbrA:
undetectable
1kt3A-4rbrA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ryk LMO0325 PROTEIN

(Listeria
monocytogenes)
PF01381
(HTH_3)
4 LEU A 224
MET A 180
TYR A 184
LEU A 200
None
1.11A 1kt3A-4rykA:
undetectable
1kt3A-4rykA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN


(Salmonella
enterica)
PF00207
(A2M)
PF01835
(A2M_N)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl)
PF11974
(MG1)
4 LEU A 585
LEU A 555
TYR A 504
LEU A 481
None
1.01A 1kt3A-4u48A:
undetectable
1kt3A-4u48A:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wfw GENERAL SECRETION
PATHWAY PROTEIN B


(Dickeya
dadantii)
PF16537
(T2SSB)
4 LEU A 187
LEU A 184
TYR A 129
LEU A 148
None
1.06A 1kt3A-4wfwA:
undetectable
1kt3A-4wfwA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wz9 AGAP004809-PA

(Anopheles
gambiae)
PF01433
(Peptidase_M1)
PF11838
(ERAP1_C)
4 LEU A 466
LEU A 475
MET A 402
LEU A 459
None
1.03A 1kt3A-4wz9A:
undetectable
1kt3A-4wz9A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wz9 AGAP004809-PA

(Anopheles
gambiae)
PF01433
(Peptidase_M1)
PF11838
(ERAP1_C)
4 LEU A 466
LEU A 475
TYR A 398
LEU A 459
None
0.93A 1kt3A-4wz9A:
undetectable
1kt3A-4wz9A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a22 VESICULAR STOMATITIS
VIRUS L POLYMERASE


(Vesicular
stomatitis
virus)
PF00946
(Mononeg_RNA_pol)
PF14314
(Methyltrans_Mon)
PF14318
(Mononeg_mRNAcap)
4 LEU A 693
LEU A 691
TYR A 606
GLN A 716
None
1.11A 1kt3A-5a22A:
undetectable
1kt3A-5a22A:
5.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5az4 FLAGELLAR HOOK
SUBUNIT PROTEIN


(Campylobacter
jejuni)
PF07196
(Flagellin_IN)
PF07559
(FlaE)
4 LEU A 509
MET A 575
TYR A 259
LEU A 492
None
1.08A 1kt3A-5az4A:
undetectable
1kt3A-5az4A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d0f UNCHARACTERIZED
PROTEIN


([Candida]
glabrata)
PF06202
(GDE_C)
PF14699
(hGDE_N)
PF14701
(hDGE_amylase)
PF14702
(hGDE_central)
4 LEU A 891
LEU A 889
TYR A 896
LEU A 898
None
1.04A 1kt3A-5d0fA:
undetectable
1kt3A-5d0fA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5du9 CDA PEPTIDE
SYNTHETASE I


(Streptomyces
coelicolor)
PF00668
(Condensation)
4 LEU A 314
LEU A 312
TYR A 215
LEU A 339
None
1.06A 1kt3A-5du9A:
undetectable
1kt3A-5du9A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hb4 NUP192,NUCLEOPORIN
NUP192


(Chaetomium
thermophilum)
PF11894
(Nup192)
4 LEU B 497
MET B 515
TYR B 475
LEU B 468
None
0.98A 1kt3A-5hb4B:
undetectable
1kt3A-5hb4B:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ir6 BD-TYPE QUINOL
OXIDASE SUBUNIT I


(Geobacillus
stearothermophilus)
PF01654
(Cyt_bd_oxida_I)
4 LEU A 365
MET A 224
MET A  34
LEU A 359
None
0.92A 1kt3A-5ir6A:
undetectable
1kt3A-5ir6A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j90 RAGB/SUSD DOMAIN
PROTEIN


(Flavobacterium
johnsoniae)
PF12741
(SusD-like)
4 LEU A 224
LEU A 140
TYR A 210
LEU A 347
None
0.99A 1kt3A-5j90A:
undetectable
1kt3A-5j90A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l46 DIMETHYLGLYCINE
DEHYDROGENASE,
MITOCHONDRIAL


(Homo sapiens)
PF01266
(DAO)
PF01571
(GCV_T)
PF08669
(GCV_T_C)
PF16350
(FAO_M)
4 LEU A 604
LEU A 581
MET A 570
TYR A 578
None
1.10A 1kt3A-5l46A:
undetectable
1kt3A-5l46A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lpy PROTEIN
BRASSINOSTEROID
INSENSITIVE 1


(Arabidopsis
thaliana)
PF00069
(Pkinase)
4 LEU A 871
LEU A 954
MET A 928
LEU A 868
None
1.03A 1kt3A-5lpyA:
undetectable
1kt3A-5lpyA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lpz PROTEIN
BRASSINOSTEROID
INSENSITIVE 1


(Arabidopsis
thaliana)
PF00069
(Pkinase)
4 LEU A 871
LEU A 954
MET A 928
LEU A 868
None
1.03A 1kt3A-5lpzA:
undetectable
1kt3A-5lpzA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lxz SECRETED PROTEIN

(Streptomyces
lividans)
PF07646
(Kelch_2)
PF09118
(DUF1929)
4 LEU B 344
LEU B 397
LEU B 619
GLN B 621
None
1.02A 1kt3A-5lxzB:
undetectable
1kt3A-5lxzB:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m3q EUKARYOTIC
TRANSLATION
INITIATION FACTOR 6


(Chaetomium
thermophilum)
PF01912
(eIF-6)
4 LEU A 176
LEU A 181
MET A 152
GLN A 140
None
1.09A 1kt3A-5m3qA:
undetectable
1kt3A-5m3qA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mgy FAD:PROTEIN FMN
TRANSFERASE


(Pseudomonas
stutzeri)
no annotation 4 LEU H  72
LEU H 192
MET H 105
LEU H  79
None
1.10A 1kt3A-5mgyH:
undetectable
1kt3A-5mgyH:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nfj MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1


(Homo sapiens)
no annotation 4 LEU A 271
LEU A 227
MET A 209
LEU A 248
None
1.10A 1kt3A-5nfjA:
undetectable
1kt3A-5nfjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN


(Bacteroides
intestinalis)
PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like)
4 LEU A 107
LEU A  84
LEU A  96
GLN A  94
None
1.10A 1kt3A-5tf0A:
undetectable
1kt3A-5tf0A:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vfr PROTEASOME SUBUNIT
ALPHA TYPE-4


(Homo sapiens)
no annotation 4 LEU I  99
MET I  72
LEU I  92
GLN I  95
None
0.85A 1kt3A-5vfrI:
undetectable
1kt3A-5vfrI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vhv ALKYLPURINE DNA
GLYCOSYLASE ALKC


(Pseudomonas
fluorescens)
no annotation 4 LEU A 162
LEU A 128
MET A 139
LEU A 153
None
0.85A 1kt3A-5vhvA:
undetectable
1kt3A-5vhvA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x1e ICMS
ICMW
ICMO (DOTL)


(Legionella
pneumophila;
Legionella
pneumophila;
Legionella
pneumophila)
PF12608
(T4bSS_IcmS)
no annotation
no annotation
4 LEU B 131
LEU A  87
MET C 712
LEU C 733
None
1.06A 1kt3A-5x1eB:
undetectable
1kt3A-5x1eB:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cty DIHYDROOROTASE

(Yersinia pestis)
no annotation 4 LEU A 162
LEU A 104
TYR A 124
LEU A 172
None
KCX  A 103 ( 4.5A)
None
None
1.10A 1kt3A-6ctyA:
undetectable
1kt3A-6ctyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6du8 -

(-)
no annotation 4 LEU A 294
LEU A 288
LEU A 200
GLN A 202
None
0.90A 1kt3A-6du8A:
undetectable
1kt3A-6du8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ftl RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN


(Skeletonema
marinoi)
no annotation 4 LEU A 403
MET A 270
TYR A 243
LEU A 201
HLU  A 174 ( 4.8A)
KCX  A 205 ( 3.6A)
KCX  A 205 ( 4.1A)
HLU  A 174 ( 3.6A)
1.01A 1kt3A-6ftlA:
undetectable
1kt3A-6ftlA:
undetectable