SIMILAR PATTERNS OF AMINO ACIDS FOR 1KQE_D_DVAD6
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1amk | TRIOSE PHOSPHATEISOMERASE (Leishmaniamexicana) |
PF00121(TIM) | 3 | TRP A 12ALA A 64VAL A 41 | None | 0.81A | 1kqeB-1amkA:undetectable1kqeD-1amkA:undetectable | 1kqeB-1amkA:11.431kqeD-1amkA:11.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ego | GLUTAREDOXIN (Escherichiacoli) |
PF00462(Glutaredoxin) | 3 | TRP A 78ALA A 85VAL A 79 | None | 0.88A | 1kqeB-1egoA:undetectable1kqeD-1egoA:undetectable | 1kqeB-1egoA:3.531kqeD-1egoA:3.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fhu | O-SUCCINYLBENZOATESYNTHASE (Escherichiacoli) |
PF13378(MR_MLE_C) | 3 | TRP A 66ALA A 72VAL A 67 | None | 0.84A | 1kqeB-1fhuA:undetectable1kqeD-1fhuA:undetectable | 1kqeB-1fhuA:5.421kqeD-1fhuA:5.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hju | BETA-1,4-GALACTANASE (Thermothelomycesthermophila) |
PF07745(Glyco_hydro_53) | 3 | TRP A 191ALA A 151VAL A 195 | None | 0.84A | 1kqeB-1hjuA:undetectable1kqeD-1hjuA:undetectable | 1kqeB-1hjuA:5.381kqeD-1hjuA:5.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iom | CITRATE SYNTHASE (Thermusthermophilus) |
PF00285(Citrate_synt) | 3 | TRP A 242ALA A 248VAL A 243 | None | 0.79A | 1kqeB-1iomA:undetectable1kqeD-1iomA:undetectable | 1kqeB-1iomA:2.501kqeD-1iomA:2.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jtd | BETA-LACTAMASEINHIBITOR PROTEIN II (Streptomycesexfoliatus) |
PF13540(RCC1_2) | 3 | TRP B 87ALA B 60VAL B 58 | None | 0.76A | 1kqeB-1jtdB:undetectable1kqeD-1jtdB:undetectable | 1kqeB-1jtdB:2.941kqeD-1jtdB:2.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jtd | BETA-LACTAMASEINHIBITOR PROTEIN II (Streptomycesexfoliatus) |
PF13540(RCC1_2) | 3 | TRP B 165ALA B 138VAL B 136 | None | 0.88A | 1kqeB-1jtdB:undetectable1kqeD-1jtdB:undetectable | 1kqeB-1jtdB:2.941kqeD-1jtdB:2.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jtd | BETA-LACTAMASEINHIBITOR PROTEIN II (Streptomycesexfoliatus) |
PF13540(RCC1_2) | 3 | TRP B 204ALA B 177VAL B 175 | None | 0.86A | 1kqeB-1jtdB:undetectable1kqeD-1jtdB:undetectable | 1kqeB-1jtdB:2.941kqeD-1jtdB:2.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jtd | BETA-LACTAMASEINHIBITOR PROTEIN II (Streptomycesexfoliatus) |
PF13540(RCC1_2) | 3 | TRP B 243ALA B 216VAL B 214 | None | 0.80A | 1kqeB-1jtdB:undetectable1kqeD-1jtdB:undetectable | 1kqeB-1jtdB:2.941kqeD-1jtdB:2.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1le8 | MATING-TYPE PROTEINALPHA-2 (Saccharomycescerevisiae) |
PF00046(Homeobox) | 3 | TRP B 179ALA B 185VAL B 180 | None | 0.77A | 1kqeB-1le8B:undetectable1kqeD-1le8B:undetectable | 1kqeB-1le8B:9.431kqeD-1le8B:9.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m6j | TRIOSEPHOSPHATEISOMERASE (Entamoebahistolytica) |
PF00121(TIM) | 3 | TRP A 12ALA A 71VAL A 44 | None | 0.88A | 1kqeB-1m6jA:undetectable1kqeD-1m6jA:undetectable | 1kqeB-1m6jA:5.111kqeD-1m6jA:5.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ofc | ISWI PROTEIN (Drosophilamelanogaster) |
PF09110(HAND)PF09111(SLIDE) | 3 | TRP X 800ALA X 840VAL X 835 | None | 0.88A | 1kqeB-1ofcX:undetectable1kqeD-1ofcX:undetectable | 1kqeB-1ofcX:3.241kqeD-1ofcX:3.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oqa | BREAST CANCER TYPE 1SUSCEPTIBILITYPROTEIN (Homo sapiens) |
PF00533(BRCT) | 3 | TRP A 84ALA A 90VAL A 85 | None | 0.81A | 1kqeB-1oqaA:undetectable1kqeD-1oqaA:undetectable | 1kqeB-1oqaA:10.291kqeD-1oqaA:10.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tcd | TRIOSEPHOSPHATEISOMERASE (Trypanosomacruzi) |
PF00121(TIM) | 3 | TRP A 13ALA A 65VAL A 42 | None | 0.85A | 1kqeB-1tcdA:undetectable1kqeD-1tcdA:undetectable | 1kqeB-1tcdA:7.271kqeD-1tcdA:7.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u2q | LOW MOLECULAR WEIGHTPROTEIN-TYROSINE-PHOSPHATASE (Mycobacteriumtuberculosis) |
PF01451(LMWPc) | 3 | TRP A 152ALA A 158VAL A 153 | None | 0.76A | 1kqeB-1u2qA:undetectable1kqeD-1u2qA:undetectable | 1kqeB-1u2qA:5.981kqeD-1u2qA:5.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w36 | EXODEOXYRIBONUCLEASEV GAMMA CHAIN (Escherichiacoli) |
PF04257(Exonuc_V_gamma) | 3 | TRP C1006ALA C 842VAL C 974 | None | 0.88A | 1kqeB-1w36C:undetectable1kqeD-1w36C:undetectable | 1kqeB-1w36C:1.671kqeD-1w36C:1.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x1n | 4-ALPHA-GLUCANOTRANSFERASE (Solanumtuberosum) |
PF02446(Glyco_hydro_77) | 3 | TRP A 286ALA A 331VAL A 274 | GOL A1002 (-3.4A)NoneNone | 0.77A | 1kqeB-1x1nA:undetectable1kqeD-1x1nA:undetectable | 1kqeB-1x1nA:5.411kqeD-1x1nA:5.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xc6 | BETA-GALACTOSIDASE (Penicillium sp.) |
PF01301(Glyco_hydro_35)PF10435(BetaGal_dom2)PF13363(BetaGal_dom3)PF13364(BetaGal_dom4_5) | 3 | TRP A 549ALA A 554VAL A 551 | None | 0.77A | 1kqeB-1xc6A:undetectable1kqeD-1xc6A:undetectable | 1kqeB-1xc6A:1.251kqeD-1xc6A:1.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yhu | HEMOGLOBIN A1 CHAIN (Riftiapachyptila) |
PF00042(Globin) | 3 | TRP A 130ALA A 115VAL A 117 | None | 0.89A | 1kqeB-1yhuA:undetectable1kqeD-1yhuA:undetectable | 1kqeB-1yhuA:5.431kqeD-1yhuA:5.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yr2 | PROLYLOLIGOPEPTIDASE (Novosphingobiumcapsulatum) |
PF00326(Peptidase_S9)PF02897(Peptidase_S9_N) | 3 | TRP A 77ALA A 83VAL A 78 | None | 0.81A | 1kqeB-1yr2A:undetectable1kqeD-1yr2A:undetectable | 1kqeB-1yr2A:3.081kqeD-1yr2A:3.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zun | SULFATE ADENYLATETRANSFERASE, SUBUNIT1/ADENYLYLSULFATEKINASE (Pseudomonassyringae groupgenomosp. 3) |
PF00009(GTP_EFTU) | 3 | TRP B 341ALA B 429VAL B 427 | None | 0.79A | 1kqeB-1zunB:undetectable1kqeD-1zunB:undetectable | 1kqeB-1zunB:2.121kqeD-1zunB:2.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b24 | NAPHTHALENEDIOXYGENASE SMALLSUBUNIT (Rhodococcus sp.NCIMB 12038) |
PF00866(Ring_hydroxyl_B) | 3 | TRP B 541ALA B 659VAL B 545 | None | 0.81A | 1kqeB-2b24B:undetectable1kqeD-2b24B:undetectable | 1kqeB-2b24B:5.981kqeD-2b24B:5.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2btm | PROTEIN(TRIOSEPHOSPHATEISOMERASE) (Geobacillusstearothermophilus) |
PF00121(TIM) | 3 | TRP A 9ALA A 62VAL A 39 | None | 0.83A | 1kqeB-2btmA:undetectable1kqeD-2btmA:undetectable | 1kqeB-2btmA:7.411kqeD-2btmA:7.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e4u | METABOTROPICGLUTAMATE RECEPTOR 3 (Rattusnorvegicus) |
PF01094(ANF_receptor)PF07562(NCD3G) | 3 | TRP A 303ALA A 286VAL A 310 | None | 0.86A | 1kqeB-2e4uA:undetectable1kqeD-2e4uA:undetectable | 1kqeB-2e4uA:9.641kqeD-2e4uA:9.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h2t | LOW AFFINITYIMMUNOGLOBULINEPSILON FC RECEPTOR(LYMPHOCYTE IGERECEPTOR)(FC-EPSILON-RII)(IMMUNOGLOBULINE-BINDING FACTOR)(CD23 ANTIGEN) (Homo sapiens) |
PF00059(Lectin_C) | 3 | TRP B 184ALA B 190VAL B 185 | None | 0.88A | 1kqeB-2h2tB:undetectable1kqeD-2h2tB:undetectable | 1kqeB-2h2tB:4.571kqeD-2h2tB:4.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2imj | HYPOTHETICAL PROTEINDUF1348 (Pseudomonasprotegens) |
PF07080(DUF1348) | 3 | TRP A 113ALA A 83VAL A 91 | None | 0.57A | 1kqeB-2imjA:undetectable1kqeD-2imjA:undetectable | 1kqeB-2imjA:11.391kqeD-2imjA:11.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jxy | MACROPHAGEMETALLOELASTASE (Homo sapiens) |
PF00045(Hemopexin) | 3 | TRP A 401ALA A 382VAL A 396 | None CA A 471 ( 4.3A)None | 0.72A | 1kqeB-2jxyA:undetectable1kqeD-2jxyA:undetectable | 1kqeB-2jxyA:4.421kqeD-2jxyA:4.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kwb | TRANSLATIONALLY-CONTROLLED TUMOR PROTEINHOMOLOG (Caenorhabditiselegans) |
PF00838(TCTP) | 3 | TRP A 123ALA A 129VAL A 124 | None | 0.85A | 1kqeB-2kwbA:undetectable1kqeD-2kwbA:undetectable | 1kqeB-2kwbA:6.671kqeD-2kwbA:6.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ms7 | MITOCHONDRIALANTIVIRAL-SIGNALINGPROTEIN (Homo sapiens) |
PF16739(CARD_2) | 3 | TRP A 68ALA A 74VAL A 69 | None | 0.83A | 1kqeB-2ms7A:undetectable1kqeD-2ms7A:undetectable | 1kqeB-2ms7A:12.121kqeD-2ms7A:12.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nog | ISWI PROTEIN (Xenopus laevis) |
PF09110(HAND) | 3 | TRP A 829ALA A 869VAL A 864 | None | 0.89A | 1kqeB-2nogA:undetectable1kqeD-2nogA:undetectable | 1kqeB-2nogA:6.381kqeD-2nogA:6.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pm9 | PROTEIN TRANSPORTPROTEIN SEC31 (Saccharomycescerevisiae) |
PF00400(WD40) | 3 | TRP A 217ALA A 173VAL A 175 | None | 0.77A | 1kqeB-2pm9A:undetectable1kqeD-2pm9A:undetectable | 1kqeB-2pm9A:3.101kqeD-2pm9A:3.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wds | HOLO-[ACYL-CARRIER-PROTEIN] SYNTHASE (Streptomycescoelicolor) |
PF01648(ACPS) | 3 | TRP A 104ALA A 97VAL A 101 | None | 0.87A | 1kqeB-2wdsA:undetectable1kqeD-2wdsA:undetectable | 1kqeB-2wdsA:9.681kqeD-2wdsA:9.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yjp | PUTATIVE ABCTRANSPORTER,PERIPLASMIC BINDINGPROTEIN, AMINO ACID (Neisseriagonorrhoeae) |
PF00497(SBP_bac_3) | 3 | TRP A 246ALA A 252VAL A 247 | None | 0.84A | 1kqeB-2yjpA:undetectable1kqeD-2yjpA:undetectable | 1kqeB-2yjpA:5.061kqeD-2yjpA:5.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yka | RNA AND EXPORTFACTOR-BINDINGPROTEIN 252 KDAIMMEDIATE-EARLYPHOSPHOPROTEIN (Mus musculus;Saimiriinegammaherpesvirus2) |
PF00076(RRM_1)no annotation | 3 | TRP B 108ALA A 89VAL A 86 | None | 0.77A | 1kqeB-2ykaB:undetectable1kqeD-2ykaB:undetectable | 1kqeB-2ykaB:16.671kqeD-2ykaB:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ylz | PHENYLACETONEMONOOXYGENASE (Thermobifidafusca) |
PF13738(Pyr_redox_3) | 3 | TRP A 456ALA A 462VAL A 457 | None | 0.82A | 1kqeB-2ylzA:undetectable1kqeD-2ylzA:undetectable | 1kqeB-2ylzA:10.471kqeD-2ylzA:10.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ziu | CROSSOVER JUNCTIONENDONUCLEASE EME1 (Homo sapiens) |
PF02732(ERCC4) | 3 | TRP B 429ALA B 318VAL B 364 | None | 0.82A | 1kqeB-2ziuB:undetectable1kqeD-2ziuB:undetectable | 1kqeB-2ziuB:2.461kqeD-2ziuB:2.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aib | GLUCOSYLTRANSFERASE-SI (Streptococcusmutans) |
PF02324(Glyco_hydro_70) | 3 | TRP A 956ALA A 478VAL A 476 | None | 0.68A | 1kqeB-3aibA:undetectable1kqeD-3aibA:undetectable | 1kqeB-3aibA:1.741kqeD-3aibA:1.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bqw | PUTATIVE CAPSIDPROTEIN OF PROPHAGE (Escherichiacoli) |
PF03864(Phage_cap_E) | 3 | TRP A 163ALA A 340VAL A 338 | None | 0.85A | 1kqeB-3bqwA:undetectable1kqeD-3bqwA:undetectable | 1kqeB-3bqwA:4.301kqeD-3bqwA:4.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d1j | GLYCOGEN SYNTHASE (Escherichiacoli) |
PF00534(Glycos_transf_1)PF08323(Glyco_transf_5) | 3 | TRP A 115ALA A 121VAL A 116 | None | 0.78A | 1kqeB-3d1jA:undetectable1kqeD-3d1jA:undetectable | 1kqeB-3d1jA:6.491kqeD-3d1jA:6.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e7q | TRANSCRIPTIONALREGULATOR (Pseudomonasaeruginosa) |
PF00440(TetR_N)PF13977(TetR_C_6) | 3 | TRP A 196ALA A 202VAL A 197 | None | 0.76A | 1kqeB-3e7qA:undetectable1kqeD-3e7qA:undetectable | 1kqeB-3e7qA:5.521kqeD-3e7qA:5.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ee4 | PROBABLERIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (Mycobacteriumtuberculosis) |
PF00268(Ribonuc_red_sm) | 3 | TRP A 111ALA A 44VAL A 115 | None | 0.84A | 1kqeB-3ee4A:undetectable1kqeD-3ee4A:undetectable | 1kqeB-3ee4A:4.601kqeD-3ee4A:4.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fbs | OXIDOREDUCTASE (Agrobacteriumfabrum) |
PF07992(Pyr_redox_2) | 3 | TRP A 230ALA A 33VAL A 79 | NoneFAD A 298 (-3.5A)FAD A 298 (-4.0A) | 0.85A | 1kqeB-3fbsA:undetectable1kqeD-3fbsA:undetectable | 1kqeB-3fbsA:10.341kqeD-3fbsA:10.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gq2 | GENERAL VESICULARTRANSPORT FACTORP115 (Bos taurus) |
PF04869(Uso1_p115_head) | 3 | TRP A 272ALA A 327VAL A 325 | None | 0.56A | 1kqeB-3gq2A:undetectable1kqeD-3gq2A:undetectable | 1kqeB-3gq2A:2.261kqeD-3gq2A:2.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hxl | UNCHARACTERIZEDPROTEIN DSY3957 (Desulfitobacteriumhafniense) |
PF04984(Phage_sheath_1)PF17481(Phage_sheath_1N)PF17482(Phage_sheath_1C) | 3 | TRP A 269ALA A 275VAL A 270 | None | 0.86A | 1kqeB-3hxlA:undetectable1kqeD-3hxlA:undetectable | 1kqeB-3hxlA:9.521kqeD-3hxlA:9.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i4i | 1,3-1,4-BETA-GLUCANASE (unculturedmurine largebowel bacteriumBAC 14) |
PF00722(Glyco_hydro_16) | 3 | TRP A 194ALA A 197VAL A 191 | None | 0.84A | 1kqeB-3i4iA:undetectable1kqeD-3i4iA:undetectable | 1kqeB-3i4iA:3.981kqeD-3i4iA:3.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3if9 | GLYCINE OXIDASE (Bacillussubtilis) |
PF01266(DAO) | 3 | TRP A 205ALA A 325VAL A 204 | None | 0.85A | 1kqeB-3if9A:undetectable1kqeD-3if9A:undetectable | 1kqeB-3if9A:2.561kqeD-3if9A:2.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lml | LIN1278 PROTEIN (Listeriainnocua) |
PF04984(Phage_sheath_1)PF17481(Phage_sheath_1N)PF17482(Phage_sheath_1C) | 3 | TRP A 275ALA A 281VAL A 276 | None | 0.79A | 1kqeB-3lmlA:undetectable1kqeD-3lmlA:undetectable | 1kqeB-3lmlA:2.901kqeD-3lmlA:2.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mfn | UNCHARACTERIZEDPROTEIN (Dyadobacterfermentans) |
no annotation | 3 | TRP A 126ALA A 132VAL A 127 | None | 0.89A | 1kqeB-3mfnA:undetectable1kqeD-3mfnA:undetectable | 1kqeB-3mfnA:5.651kqeD-3mfnA:5.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3muo | PROLYL ENDOPEPTIDASE (Aeromonascaviae) |
PF00326(Peptidase_S9)PF02897(Peptidase_S9_N) | 3 | TRP A 44ALA A 50VAL A 45 | None | 0.88A | 1kqeB-3muoA:undetectable1kqeD-3muoA:undetectable | 1kqeB-3muoA:2.111kqeD-3muoA:2.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mz1 | PUTATIVETRANSCRIPTIONALREGULATOR (Sinorhizobiummeliloti) |
PF03466(LysR_substrate) | 3 | TRP A 284ALA A 290VAL A 285 | None | 0.81A | 1kqeB-3mz1A:undetectable1kqeD-3mz1A:undetectable | 1kqeB-3mz1A:2.141kqeD-3mz1A:2.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nqp | SUSD SUPERFAMILYPROTEIN (Bacteroidesfragilis) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 3 | TRP A 408ALA A 414VAL A 409 | None | 0.87A | 1kqeB-3nqpA:undetectable1kqeD-3nqpA:undetectable | 1kqeB-3nqpA:2.111kqeD-3nqpA:2.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3orj | SUGAR-BINDINGPROTEIN (Bacteroidesovatus) |
no annotation | 3 | TRP A 389ALA A 400VAL A 395 | None | 0.89A | 1kqeB-3orjA:undetectable1kqeD-3orjA:undetectable | 1kqeB-3orjA:3.121kqeD-3orjA:3.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qw2 | MYO-INOSITOL-1-PHOSPHATE SYNTHASE (INO1) (Archaeoglobusfulgidus) |
PF01658(Inos-1-P_synth)PF07994(NAD_binding_5) | 3 | TRP A 387ALA A 363VAL A 359 | None | 0.83A | 1kqeB-3qw2A:undetectable1kqeD-3qw2A:undetectable | 1kqeB-3qw2A:4.761kqeD-3qw2A:4.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r7p | RIBOSOMAL PROTEIN3/HOMINGENDONUCLEASE-LIKEFUSION PROTEIN (Leptographiumtruncatum) |
PF00961(LAGLIDADG_1) | 3 | TRP A 176ALA A 182VAL A 177 | None | 0.81A | 1kqeB-3r7pA:undetectable1kqeD-3r7pA:undetectable | 1kqeB-3r7pA:4.651kqeD-3r7pA:4.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3th6 | TRIOSEPHOSPHATEISOMERASE (Rhipicephalusmicroplus) |
PF00121(TIM) | 3 | TRP A 12ALA A 63VAL A 41 | None | 0.88A | 1kqeB-3th6A:undetectable1kqeD-3th6A:undetectable | 1kqeB-3th6A:7.021kqeD-3th6A:7.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vgl | GLUCOKINASE (Streptomycesgriseus) |
PF00480(ROK) | 3 | TRP A 83ALA A 73VAL A 75 | None | 0.80A | 1kqeB-3vglA:undetectable1kqeD-3vglA:undetectable | 1kqeB-3vglA:3.661kqeD-3vglA:3.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vgp | TRANSMEMBRANEOLIGOSACCHARYLTRANSFERASE,PUTATIVE (Archaeoglobusfulgidus) |
no annotation | 3 | TRP A 471ALA A 479VAL A 475 | None | 0.80A | 1kqeB-3vgpA:undetectable1kqeD-3vgpA:undetectable | 1kqeB-3vgpA:6.191kqeD-3vgpA:6.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vqr | PUTATIVEOXIDOREDUCTASE (Aeropyrumpernix) |
PF01266(DAO) | 3 | TRP A 233ALA A 374VAL A 232 | FAD A1001 (-4.7A)EDO A1003 ( 4.0A)ACT A1002 ( 3.3A) | 0.87A | 1kqeB-3vqrA:undetectable1kqeD-3vqrA:undetectable | 1kqeB-3vqrA:2.651kqeD-3vqrA:2.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wct | A1 GLOBIN CHAIN OFGIANT V2 HEMOGLOBIN (Lamellibrachiasatsuma) |
PF00042(Globin) | 3 | TRP A 128ALA A 113VAL A 115 | None | 0.89A | 1kqeB-3wctA:undetectable1kqeD-3wctA:undetectable | 1kqeB-3wctA:5.221kqeD-3wctA:5.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wrf | NON-REDUCING ENDBETA-L-ARABINOFURANOSIDASE (Bifidobacteriumlongum) |
PF07944(Glyco_hydro_127) | 3 | TRP A 469ALA A 593VAL A 602 | None | 0.83A | 1kqeB-3wrfA:undetectable1kqeD-3wrfA:undetectable | 1kqeB-3wrfA:1.901kqeD-3wrfA:1.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zxl | HIAXHD3 (Humicolainsolens) |
PF04616(Glyco_hydro_43) | 3 | TRP A 437ALA A 468VAL A 448 | None | 0.78A | 1kqeB-3zxlA:undetectable1kqeD-3zxlA:undetectable | 1kqeB-3zxlA:2.001kqeD-3zxlA:2.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4amc | GLUCANSUCRASE (Lactobacillusreuteri) |
PF01473(CW_binding_1)PF02324(Glyco_hydro_70) | 3 | TRP A1510ALA A1025VAL A1023 | None | 0.77A | 1kqeB-4amcA:undetectable1kqeD-4amcA:undetectable | 1kqeB-4amcA:3.861kqeD-4amcA:3.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ap3 | STEROIDMONOOXYGENASE (Rhodococcusrhodochrous) |
PF00743(FMO-like) | 3 | TRP A 461ALA A 467VAL A 462 | None | 0.85A | 1kqeB-4ap3A:undetectable1kqeD-4ap3A:undetectable | 1kqeB-4ap3A:11.111kqeD-4ap3A:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ayg | GLUCANSUCRASE (Lactobacillusreuteri) |
PF01473(CW_binding_1)PF02324(Glyco_hydro_70) | 3 | TRP A1505ALA A1026VAL A1024 | NoneGOL A2791 (-3.6A)None | 0.72A | 1kqeB-4aygA:undetectable1kqeD-4aygA:undetectable | 1kqeB-4aygA:3.451kqeD-4aygA:3.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bzk | PROTEIN TRANSPORTPROTEIN SEC31 (Saccharomycescerevisiae) |
PF00400(WD40)PF12931(Sec16_C) | 3 | TRP A 217ALA A 173VAL A 175 | None | 0.77A | 1kqeB-4bzkA:undetectable1kqeD-4bzkA:undetectable | 1kqeB-4bzkA:1.091kqeD-4bzkA:1.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gxw | ADENOSINE DEAMINASE (Burkholderiaambifaria) |
PF00962(A_deaminase) | 3 | TRP A 279ALA A 10VAL A 8 | None | 0.82A | 1kqeB-4gxwA:undetectable1kqeD-4gxwA:undetectable | 1kqeB-4gxwA:3.321kqeD-4gxwA:3.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h2h | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME (Salipigerbermudensis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | TRP A 295ALA A 327VAL A 15 | None | 0.87A | 1kqeB-4h2hA:undetectable1kqeD-4h2hA:undetectable | 1kqeB-4h2hA:3.021kqeD-4h2hA:3.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4izg | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME,N-TERMINAL DOMAINPROTEIN (Paracoccusdenitrificans) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | TRP A 296ALA A 328VAL A 15 | None | 0.87A | 1kqeB-4izgA:undetectable1kqeD-4izgA:undetectable | 1kqeB-4izgA:5.591kqeD-4izgA:5.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jnd | CA(2+)/CALMODULIN-DEPENDENT PROTEINKINASE PHOSPHATASE (Caenorhabditiselegans) |
PF00481(PP2C) | 3 | TRP A 92ALA A 98VAL A 93 | None | 0.81A | 1kqeB-4jndA:undetectable1kqeD-4jndA:undetectable | 1kqeB-4jndA:2.131kqeD-4jndA:2.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lzh | L,D-TRANSPEPTIDASE (Klebsiellapneumoniae) |
PF03734(YkuD) | 3 | TRP A 149ALA A 168VAL A 170 | None | 0.84A | 1kqeB-4lzhA:undetectable1kqeD-4lzhA:undetectable | 1kqeB-4lzhA:7.871kqeD-4lzhA:7.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m8u | OLIGO-1,6-GLUCOSIDASE 1 (Bacillussubtilis) |
PF00128(Alpha-amylase)PF16657(Malt_amylase_C) | 3 | TRP A 172ALA A 200VAL A 100 | NoneTRS A 601 ( 4.0A)None | 0.81A | 1kqeB-4m8uA:undetectable1kqeD-4m8uA:undetectable | 1kqeB-4m8uA:6.631kqeD-4m8uA:6.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mag | SIALIC ACID BINDINGPROTEIN (Vibrio cholerae) |
PF03480(DctP) | 3 | TRP A 120ALA A 65VAL A 214 | None | 0.78A | 1kqeB-4magA:undetectable1kqeD-4magA:undetectable | 1kqeB-4magA:4.051kqeD-4magA:4.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o7p | MALTOKINASE (Mycobacteriumtuberculosis) |
no annotation | 3 | TRP A 392ALA A 398VAL A 393 | None | 0.78A | 1kqeB-4o7pA:undetectable1kqeD-4o7pA:undetectable | 1kqeB-4o7pA:2.061kqeD-4o7pA:2.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4otm | SERINE/THREONINE-PROTEIN KINASE GCN2 (Saccharomycescerevisiae) |
PF12745(HGTP_anticodon2) | 3 | TRP A1560ALA A1566VAL A1561 | None | 0.78A | 1kqeB-4otmA:undetectable1kqeD-4otmA:undetectable | 1kqeB-4otmA:7.141kqeD-4otmA:7.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s38 | 4-HYDROXY-3-METHYLBUT-2-EN-1-YLDIPHOSPHATE SYNTHASE (Thermusthermophilus) |
PF04551(GcpE) | 3 | TRP A 213ALA A 219VAL A 214 | None | 0.81A | 1kqeB-4s38A:undetectable1kqeD-4s38A:undetectable | 1kqeB-4s38A:2.971kqeD-4s38A:2.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4trg | SIDC (Legionellapneumophila) |
no annotation | 3 | TRP A 323ALA A 316VAL A 318 | None | 0.81A | 1kqeB-4trgA:undetectable1kqeD-4trgA:undetectable | 1kqeB-4trgA:3.051kqeD-4trgA:3.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u98 | MALTOKINASE (Mycolicibacteriumvanbaalenii) |
PF01636(APH) | 3 | TRP A 379ALA A 385VAL A 380 | None | 0.76A | 1kqeB-4u98A:undetectable1kqeD-4u98A:undetectable | 1kqeB-4u98A:1.871kqeD-4u98A:1.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wrw | URACIL-DNAGLYCOSYLASE (Mycobacteriumtuberculosis) |
PF03167(UDG) | 3 | TRP A 145ALA A 52VAL A 49 | None | 0.86A | 1kqeB-4wrwA:undetectable1kqeD-4wrwA:undetectable | 1kqeB-4wrwA:8.641kqeD-4wrwA:8.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xhb | SIALIDASE B (Streptococcuspneumoniae) |
PF02012(BNR)PF02973(Sialidase)PF13088(BNR_2) | 3 | TRP A 308ALA A 241VAL A 306 | None | 0.74A | 1kqeB-4xhbA:undetectable1kqeD-4xhbA:undetectable | 1kqeB-4xhbA:1.441kqeD-4xhbA:1.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xwh | ALPHA-N-ACETYLGLUCOSAMINIDASE (Homo sapiens) |
PF05089(NAGLU)PF12971(NAGLU_N)PF12972(NAGLU_C) | 3 | TRP A 474ALA A 480VAL A 475 | None | 0.89A | 1kqeB-4xwhA:undetectable1kqeD-4xwhA:undetectable | 1kqeB-4xwhA:1.771kqeD-4xwhA:1.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z1p | CELL WALL SURFACEANCHOR PROTEIN (Streptococcusagalactiae) |
PF16364(Antigen_C) | 3 | TRP A 206ALA A 210VAL A 208 | None | 0.70A | 1kqeB-4z1pA:undetectable1kqeD-4z1pA:undetectable | 1kqeB-4z1pA:3.741kqeD-4z1pA:3.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z23 | CELL WALL SURFACEANCHOR PROTEIN (Streptococcusagalactiae) |
PF16364(Antigen_C) | 3 | TRP A 206ALA A 210VAL A 208 | None | 0.76A | 1kqeB-4z23A:undetectable1kqeD-4z23A:undetectable | 1kqeB-4z23A:3.741kqeD-4z23A:3.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zfm | PUTATIVE6-PHOSPHO-BETA-GALACTOBIOSIDASE (Geobacillusstearothermophilus) |
PF00232(Glyco_hydro_1) | 3 | TRP A 466ALA A 476VAL A 470 | None | 0.79A | 1kqeB-4zfmA:undetectable1kqeD-4zfmA:undetectable | 1kqeB-4zfmA:2.191kqeD-4zfmA:2.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a29 | EXOPOLYGALACTURONATELYASE (Vibriovulnificus) |
PF06917(Pectate_lyase_2) | 3 | TRP A 184ALA A 179VAL A 181 | None | 0.84A | 1kqeB-5a29A:undetectable1kqeD-5a29A:undetectable | 1kqeB-5a29A:2.751kqeD-5a29A:2.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bp1 | MYCOCEROSIC ACIDSYNTHASE (Mycolicibacteriumsmegmatis) |
PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 3 | TRP A 716ALA A 682VAL A 677 | None | 0.85A | 1kqeB-5bp1A:undetectable1kqeD-5bp1A:undetectable | 1kqeB-5bp1A:1.631kqeD-5bp1A:1.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cho | FLAVIN REDUCTASE (unculturedbacterium) |
PF01613(Flavin_Reduct) | 3 | TRP A 152ALA A 154VAL A 164 | None | 0.88A | 1kqeB-5choA:undetectable1kqeD-5choA:undetectable | 1kqeB-5choA:7.691kqeD-5choA:7.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5csu | 4-ALPHA-GLUCANOTRANSFERASE DPE1,CHLOROPLASTIC/AMYLOPLASTIC (Arabidopsisthaliana) |
PF02446(Glyco_hydro_77) | 3 | TRP A 338ALA A 383VAL A 326 | HMC A 606 ( 3.6A)NoneNone | 0.81A | 1kqeB-5csuA:undetectable1kqeD-5csuA:undetectable | 1kqeB-5csuA:4.441kqeD-5csuA:4.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dgt | BENZOYLFORMATEDECARBOXYLASE (Pseudomonasputida) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 3 | TRP A 163ALA A 96VAL A 158 | None | 0.85A | 1kqeB-5dgtA:undetectable1kqeD-5dgtA:undetectable | 1kqeB-5dgtA:2.381kqeD-5dgtA:2.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5er3 | SUGAR ABCTRANSPORTER,PERIPLASMICSUGAR-BINDINGPROTEIN (Rhodopirellulabaltica) |
PF13407(Peripla_BP_4) | 3 | TRP A 91ALA A 70VAL A 335 | None | 0.89A | 1kqeB-5er3A:undetectable1kqeD-5er3A:undetectable | 1kqeB-5er3A:4.571kqeD-5er3A:4.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g5u | BETA-HEXOSAMINIDASE (Pseudomonasaeruginosa) |
PF00933(Glyco_hydro_3) | 3 | TRP A 226ALA A 181VAL A 215 | None | 0.85A | 1kqeB-5g5uA:undetectable1kqeD-5g5uA:undetectable | 1kqeB-5g5uA:3.301kqeD-5g5uA:3.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gn5 | GLYCEROL KINASE (Trypanosomabrucei) |
PF00370(FGGY_N)PF02782(FGGY_C) | 3 | TRP A 465ALA A 461VAL A 464 | None | 0.86A | 1kqeB-5gn5A:undetectable1kqeD-5gn5A:undetectable | 1kqeB-5gn5A:1.561kqeD-5gn5A:1.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5irp | ALANINE RACEMASE 2 (Bacillussubtilis) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 3 | TRP A 163ALA A 157VAL A 152 | None | 0.87A | 1kqeB-5irpA:undetectable1kqeD-5irpA:undetectable | 1kqeB-5irpA:2.111kqeD-5irpA:2.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5na7 | PUTATIVEDIPEPTIDYL-PEPTIDASEIII (Bacteroidesthetaiotaomicron) |
no annotation | 3 | TRP A 543ALA A 549VAL A 544 | None | 0.76A | 1kqeB-5na7A:undetectable1kqeD-5na7A:undetectable | 1kqeB-5na7A:3.441kqeD-5na7A:3.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5njf | METALLOPROTEASE PMBA (Escherichiacoli) |
PF01523(PmbA_TldD) | 3 | TRP B 221ALA B 227VAL B 222 | None | 0.83A | 1kqeB-5njfB:undetectable1kqeD-5njfB:undetectable | 1kqeB-5njfB:2.411kqeD-5njfB:2.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nl7 | CALPONIN HOMOLOGYDOMAIN PROTEINPUTATIVE (Entamoebahistolytica) |
no annotation | 3 | TRP A 21ALA A 27VAL A 22 | None | 0.82A | 1kqeB-5nl7A:undetectable1kqeD-5nl7A:undetectable | 1kqeB-5nl7A:undetectable1kqeD-5nl7A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uxb | MACROLIDE2'-PHOSPHOTRANSFERASE MPHH (Brachybacteriumfaecium) |
PF01636(APH) | 3 | TRP A 215ALA A 77VAL A 212 | None | 0.84A | 1kqeB-5uxbA:undetectable1kqeD-5uxbA:undetectable | 1kqeB-5uxbA:4.021kqeD-5uxbA:4.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vm1 | XYLULOKINASE (Brucella ovis) |
PF00370(FGGY_N)PF02782(FGGY_C) | 3 | TRP A 135ALA A 141VAL A 136 | None | 0.87A | 1kqeB-5vm1A:undetectable1kqeD-5vm1A:undetectable | 1kqeB-5vm1A:5.701kqeD-5vm1A:5.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vwn | TRIOSEPHOSPHATEISOMERASE (Trichomonasvaginalis) |
no annotation | 3 | TRP A 152ALA A 193VAL A 191 | None | 0.75A | 1kqeB-5vwnA:undetectable1kqeD-5vwnA:undetectable | 1kqeB-5vwnA:undetectable1kqeD-5vwnA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yj6 | DOCKERIN TYPE IREPEAT-CONTAININGPROTEIN (Ruminiclostridiumthermocellum) |
no annotation | 3 | TRP A 358ALA A 367VAL A 359 | None | 0.89A | 1kqeB-5yj6A:undetectable1kqeD-5yj6A:undetectable | 1kqeB-5yj6A:undetectable1kqeD-5yj6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z6v | ABC-TYPEUNCHARACTERIZEDTRANSPORT SYSTEMPERIPLASMICCOMPONENT-LIKEPROTEIN (Rhodothermusmarinus) |
no annotation | 3 | TRP A 148ALA A 144VAL A 146 | None | 0.88A | 1kqeB-5z6vA:undetectable1kqeD-5z6vA:undetectable | 1kqeB-5z6vA:undetectable1kqeD-5z6vA:undetectable |