SIMILAR PATTERNS OF AMINO ACIDS FOR 1KQE_A_DVAA6_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1amk | TRIOSE PHOSPHATEISOMERASE (Leishmaniamexicana) |
PF00121(TIM) | 3 | ALA A 64VAL A 41TRP A 12 | None | 0.82A | 1kqeA-1amkA:undetectable1kqeE-1amkA:undetectable | 1kqeA-1amkA:11.431kqeE-1amkA:11.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fhu | O-SUCCINYLBENZOATESYNTHASE (Escherichiacoli) |
PF13378(MR_MLE_C) | 3 | ALA A 72VAL A 67TRP A 66 | None | 0.85A | 1kqeA-1fhuA:undetectable1kqeE-1fhuA:undetectable | 1kqeA-1fhuA:5.421kqeE-1fhuA:5.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hju | BETA-1,4-GALACTANASE (Thermothelomycesthermophila) |
PF07745(Glyco_hydro_53) | 3 | ALA A 151VAL A 195TRP A 191 | None | 0.83A | 1kqeA-1hjuA:undetectable1kqeE-1hjuA:undetectable | 1kqeA-1hjuA:5.381kqeE-1hjuA:5.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iom | CITRATE SYNTHASE (Thermusthermophilus) |
PF00285(Citrate_synt) | 3 | ALA A 248VAL A 243TRP A 242 | None | 0.79A | 1kqeA-1iomA:undetectable1kqeE-1iomA:undetectable | 1kqeA-1iomA:2.501kqeE-1iomA:2.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jtd | BETA-LACTAMASEINHIBITOR PROTEIN II (Streptomycesexfoliatus) |
PF13540(RCC1_2) | 3 | ALA B 60VAL B 58TRP B 87 | None | 0.76A | 1kqeA-1jtdB:undetectable1kqeE-1jtdB:undetectable | 1kqeA-1jtdB:2.941kqeE-1jtdB:2.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jtd | BETA-LACTAMASEINHIBITOR PROTEIN II (Streptomycesexfoliatus) |
PF13540(RCC1_2) | 3 | ALA B 138VAL B 136TRP B 165 | None | 0.87A | 1kqeA-1jtdB:undetectable1kqeE-1jtdB:undetectable | 1kqeA-1jtdB:2.941kqeE-1jtdB:2.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jtd | BETA-LACTAMASEINHIBITOR PROTEIN II (Streptomycesexfoliatus) |
PF13540(RCC1_2) | 3 | ALA B 177VAL B 175TRP B 204 | None | 0.85A | 1kqeA-1jtdB:undetectable1kqeE-1jtdB:undetectable | 1kqeA-1jtdB:2.941kqeE-1jtdB:2.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jtd | BETA-LACTAMASEINHIBITOR PROTEIN II (Streptomycesexfoliatus) |
PF13540(RCC1_2) | 3 | ALA B 216VAL B 214TRP B 243 | None | 0.79A | 1kqeA-1jtdB:undetectable1kqeE-1jtdB:undetectable | 1kqeA-1jtdB:2.941kqeE-1jtdB:2.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1le8 | MATING-TYPE PROTEINALPHA-2 (Saccharomycescerevisiae) |
PF00046(Homeobox) | 3 | ALA B 185VAL B 180TRP B 179 | None | 0.77A | 1kqeA-1le8B:undetectable1kqeE-1le8B:undetectable | 1kqeA-1le8B:9.431kqeE-1le8B:9.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ofc | ISWI PROTEIN (Drosophilamelanogaster) |
PF09110(HAND)PF09111(SLIDE) | 3 | ALA X 840VAL X 835TRP X 800 | None | 0.87A | 1kqeA-1ofcX:undetectable1kqeE-1ofcX:undetectable | 1kqeA-1ofcX:3.241kqeE-1ofcX:3.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oqa | BREAST CANCER TYPE 1SUSCEPTIBILITYPROTEIN (Homo sapiens) |
PF00533(BRCT) | 3 | ALA A 90VAL A 85TRP A 84 | None | 0.81A | 1kqeA-1oqaA:undetectable1kqeE-1oqaA:undetectable | 1kqeA-1oqaA:10.291kqeE-1oqaA:10.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r6x | ATP:SULFATEADENYLYLTRANSFERASE (Saccharomycescerevisiae) |
PF01747(ATP-sulfurylase)PF14306(PUA_2) | 3 | ALA A 149VAL A 88TRP A 35 | None | 0.89A | 1kqeA-1r6xA:undetectable1kqeE-1r6xA:undetectable | 1kqeA-1r6xA:4.811kqeE-1r6xA:4.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tcd | TRIOSEPHOSPHATEISOMERASE (Trypanosomacruzi) |
PF00121(TIM) | 3 | ALA A 65VAL A 42TRP A 13 | None | 0.86A | 1kqeA-1tcdA:undetectable1kqeE-1tcdA:undetectable | 1kqeA-1tcdA:7.271kqeE-1tcdA:7.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u2q | LOW MOLECULAR WEIGHTPROTEIN-TYROSINE-PHOSPHATASE (Mycobacteriumtuberculosis) |
PF01451(LMWPc) | 3 | ALA A 158VAL A 153TRP A 152 | None | 0.76A | 1kqeA-1u2qA:undetectable1kqeE-1u2qA:undetectable | 1kqeA-1u2qA:5.981kqeE-1u2qA:5.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x1n | 4-ALPHA-GLUCANOTRANSFERASE (Solanumtuberosum) |
PF02446(Glyco_hydro_77) | 3 | ALA A 331VAL A 274TRP A 286 | NoneNoneGOL A1002 (-3.4A) | 0.79A | 1kqeA-1x1nA:undetectable1kqeE-1x1nA:undetectable | 1kqeA-1x1nA:5.411kqeE-1x1nA:5.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xc6 | BETA-GALACTOSIDASE (Penicillium sp.) |
PF01301(Glyco_hydro_35)PF10435(BetaGal_dom2)PF13363(BetaGal_dom3)PF13364(BetaGal_dom4_5) | 3 | ALA A 554VAL A 551TRP A 549 | None | 0.75A | 1kqeA-1xc6A:undetectable1kqeE-1xc6A:undetectable | 1kqeA-1xc6A:1.251kqeE-1xc6A:1.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yhu | HEMOGLOBIN A1 CHAIN (Riftiapachyptila) |
PF00042(Globin) | 3 | ALA A 115VAL A 117TRP A 130 | None | 0.88A | 1kqeA-1yhuA:undetectable1kqeE-1yhuA:undetectable | 1kqeA-1yhuA:5.431kqeE-1yhuA:5.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yr2 | PROLYLOLIGOPEPTIDASE (Novosphingobiumcapsulatum) |
PF00326(Peptidase_S9)PF02897(Peptidase_S9_N) | 3 | ALA A 83VAL A 78TRP A 77 | None | 0.81A | 1kqeA-1yr2A:undetectable1kqeE-1yr2A:undetectable | 1kqeA-1yr2A:3.081kqeE-1yr2A:3.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zun | SULFATE ADENYLATETRANSFERASE, SUBUNIT1/ADENYLYLSULFATEKINASE (Pseudomonassyringae groupgenomosp. 3) |
PF00009(GTP_EFTU) | 3 | ALA B 429VAL B 427TRP B 341 | None | 0.80A | 1kqeA-1zunB:undetectable1kqeE-1zunB:undetectable | 1kqeA-1zunB:2.121kqeE-1zunB:2.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b24 | NAPHTHALENEDIOXYGENASE SMALLSUBUNIT (Rhodococcus sp.NCIMB 12038) |
PF00866(Ring_hydroxyl_B) | 3 | ALA B 659VAL B 545TRP B 541 | None | 0.78A | 1kqeA-2b24B:undetectable1kqeE-2b24B:undetectable | 1kqeA-2b24B:5.981kqeE-2b24B:5.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2btm | PROTEIN(TRIOSEPHOSPHATEISOMERASE) (Geobacillusstearothermophilus) |
PF00121(TIM) | 3 | ALA A 62VAL A 39TRP A 9 | None | 0.85A | 1kqeA-2btmA:undetectable1kqeE-2btmA:undetectable | 1kqeA-2btmA:7.411kqeE-2btmA:7.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d2e | SUFC PROTEIN (Thermusthermophilus) |
PF00005(ABC_tran) | 3 | ALA A 183VAL A 181TRP A 131 | None | 0.87A | 1kqeA-2d2eA:undetectable1kqeE-2d2eA:undetectable | 1kqeA-2d2eA:10.261kqeE-2d2eA:10.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e4u | METABOTROPICGLUTAMATE RECEPTOR 3 (Rattusnorvegicus) |
PF01094(ANF_receptor)PF07562(NCD3G) | 3 | ALA A 286VAL A 310TRP A 303 | None | 0.84A | 1kqeA-2e4uA:undetectable1kqeE-2e4uA:undetectable | 1kqeA-2e4uA:9.641kqeE-2e4uA:9.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h2t | LOW AFFINITYIMMUNOGLOBULINEPSILON FC RECEPTOR(LYMPHOCYTE IGERECEPTOR)(FC-EPSILON-RII)(IMMUNOGLOBULINE-BINDING FACTOR)(CD23 ANTIGEN) (Homo sapiens) |
PF00059(Lectin_C) | 3 | ALA B 190VAL B 185TRP B 184 | None | 0.89A | 1kqeA-2h2tB:undetectable1kqeE-2h2tB:undetectable | 1kqeA-2h2tB:4.571kqeE-2h2tB:4.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2imj | HYPOTHETICAL PROTEINDUF1348 (Pseudomonasprotegens) |
PF07080(DUF1348) | 3 | ALA A 83VAL A 91TRP A 113 | None | 0.55A | 1kqeA-2imjA:undetectable1kqeE-2imjA:undetectable | 1kqeA-2imjA:11.391kqeE-2imjA:11.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jxy | MACROPHAGEMETALLOELASTASE (Homo sapiens) |
PF00045(Hemopexin) | 3 | ALA A 382VAL A 396TRP A 401 | CA A 471 ( 4.3A)NoneNone | 0.71A | 1kqeA-2jxyA:undetectable1kqeE-2jxyA:undetectable | 1kqeA-2jxyA:4.421kqeE-2jxyA:4.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kwb | TRANSLATIONALLY-CONTROLLED TUMOR PROTEINHOMOLOG (Caenorhabditiselegans) |
PF00838(TCTP) | 3 | ALA A 129VAL A 124TRP A 123 | None | 0.86A | 1kqeA-2kwbA:undetectable1kqeE-2kwbA:undetectable | 1kqeA-2kwbA:6.671kqeE-2kwbA:6.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ms7 | MITOCHONDRIALANTIVIRAL-SIGNALINGPROTEIN (Homo sapiens) |
PF16739(CARD_2) | 3 | ALA A 74VAL A 69TRP A 68 | None | 0.83A | 1kqeA-2ms7A:undetectable1kqeE-2ms7A:undetectable | 1kqeA-2ms7A:12.121kqeE-2ms7A:12.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nog | ISWI PROTEIN (Xenopus laevis) |
PF09110(HAND) | 3 | ALA A 869VAL A 864TRP A 829 | None | 0.88A | 1kqeA-2nogA:undetectable1kqeE-2nogA:undetectable | 1kqeA-2nogA:6.381kqeE-2nogA:6.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pm9 | PROTEIN TRANSPORTPROTEIN SEC31 (Saccharomycescerevisiae) |
PF00400(WD40) | 3 | ALA A 173VAL A 175TRP A 217 | None | 0.76A | 1kqeA-2pm9A:undetectable1kqeE-2pm9A:undetectable | 1kqeA-2pm9A:3.101kqeE-2pm9A:3.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wds | HOLO-[ACYL-CARRIER-PROTEIN] SYNTHASE (Streptomycescoelicolor) |
PF01648(ACPS) | 3 | ALA A 97VAL A 101TRP A 104 | None | 0.87A | 1kqeA-2wdsA:undetectable1kqeE-2wdsA:undetectable | 1kqeA-2wdsA:9.681kqeE-2wdsA:9.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yjp | PUTATIVE ABCTRANSPORTER,PERIPLASMIC BINDINGPROTEIN, AMINO ACID (Neisseriagonorrhoeae) |
PF00497(SBP_bac_3) | 3 | ALA A 252VAL A 247TRP A 246 | None | 0.85A | 1kqeA-2yjpA:undetectable1kqeE-2yjpA:undetectable | 1kqeA-2yjpA:5.061kqeE-2yjpA:5.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yka | RNA AND EXPORTFACTOR-BINDINGPROTEIN 252 KDAIMMEDIATE-EARLYPHOSPHOPROTEIN (Mus musculus;Saimiriinegammaherpesvirus2) |
PF00076(RRM_1)no annotation | 3 | ALA A 89VAL A 86TRP B 108 | None | 0.76A | 1kqeA-2ykaA:undetectable1kqeE-2ykaA:undetectable | 1kqeA-2ykaA:12.961kqeE-2ykaA:12.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ylz | PHENYLACETONEMONOOXYGENASE (Thermobifidafusca) |
PF13738(Pyr_redox_3) | 3 | ALA A 462VAL A 457TRP A 456 | None | 0.82A | 1kqeA-2ylzA:undetectable1kqeE-2ylzA:undetectable | 1kqeA-2ylzA:10.471kqeE-2ylzA:10.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ziu | CROSSOVER JUNCTIONENDONUCLEASE EME1 (Homo sapiens) |
PF02732(ERCC4) | 3 | ALA B 318VAL B 364TRP B 429 | None | 0.81A | 1kqeA-2ziuB:undetectable1kqeE-2ziuB:undetectable | 1kqeA-2ziuB:2.461kqeE-2ziuB:2.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aib | GLUCOSYLTRANSFERASE-SI (Streptococcusmutans) |
PF02324(Glyco_hydro_70) | 3 | ALA A 478VAL A 476TRP A 956 | None | 0.68A | 1kqeA-3aibA:undetectable1kqeE-3aibA:undetectable | 1kqeA-3aibA:1.741kqeE-3aibA:1.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b0h | NITRITE REDUCTASE (Nicotianatabacum) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 3 | ALA A 245VAL A 227TRP A 225 | None | 0.88A | 1kqeA-3b0hA:undetectable1kqeE-3b0hA:undetectable | 1kqeA-3b0hA:2.931kqeE-3b0hA:2.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bqw | PUTATIVE CAPSIDPROTEIN OF PROPHAGE (Escherichiacoli) |
PF03864(Phage_cap_E) | 3 | ALA A 340VAL A 338TRP A 163 | None | 0.84A | 1kqeA-3bqwA:undetectable1kqeE-3bqwA:undetectable | 1kqeA-3bqwA:4.301kqeE-3bqwA:4.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d1j | GLYCOGEN SYNTHASE (Escherichiacoli) |
PF00534(Glycos_transf_1)PF08323(Glyco_transf_5) | 3 | ALA A 121VAL A 116TRP A 115 | None | 0.79A | 1kqeA-3d1jA:undetectable1kqeE-3d1jA:undetectable | 1kqeA-3d1jA:6.491kqeE-3d1jA:6.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e7q | TRANSCRIPTIONALREGULATOR (Pseudomonasaeruginosa) |
PF00440(TetR_N)PF13977(TetR_C_6) | 3 | ALA A 202VAL A 197TRP A 196 | None | 0.77A | 1kqeA-3e7qA:undetectable1kqeE-3e7qA:undetectable | 1kqeA-3e7qA:5.521kqeE-3e7qA:5.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ee4 | PROBABLERIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (Mycobacteriumtuberculosis) |
PF00268(Ribonuc_red_sm) | 3 | ALA A 44VAL A 115TRP A 111 | None | 0.85A | 1kqeA-3ee4A:undetectable1kqeE-3ee4A:undetectable | 1kqeA-3ee4A:4.601kqeE-3ee4A:4.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fbs | OXIDOREDUCTASE (Agrobacteriumfabrum) |
PF07992(Pyr_redox_2) | 3 | ALA A 33VAL A 79TRP A 230 | FAD A 298 (-3.5A)FAD A 298 (-4.0A)None | 0.85A | 1kqeA-3fbsA:undetectable1kqeE-3fbsA:undetectable | 1kqeA-3fbsA:10.341kqeE-3fbsA:10.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gq2 | GENERAL VESICULARTRANSPORT FACTORP115 (Bos taurus) |
PF04869(Uso1_p115_head) | 3 | ALA A 327VAL A 325TRP A 272 | None | 0.55A | 1kqeA-3gq2A:undetectable1kqeE-3gq2A:undetectable | 1kqeA-3gq2A:2.261kqeE-3gq2A:2.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hxl | UNCHARACTERIZEDPROTEIN DSY3957 (Desulfitobacteriumhafniense) |
PF04984(Phage_sheath_1)PF17481(Phage_sheath_1N)PF17482(Phage_sheath_1C) | 3 | ALA A 275VAL A 270TRP A 269 | None | 0.86A | 1kqeA-3hxlA:undetectable1kqeE-3hxlA:undetectable | 1kqeA-3hxlA:9.521kqeE-3hxlA:9.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i4i | 1,3-1,4-BETA-GLUCANASE (unculturedmurine largebowel bacteriumBAC 14) |
PF00722(Glyco_hydro_16) | 3 | ALA A 197VAL A 191TRP A 194 | None | 0.82A | 1kqeA-3i4iA:undetectable1kqeE-3i4iA:undetectable | 1kqeA-3i4iA:3.981kqeE-3i4iA:3.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3if9 | GLYCINE OXIDASE (Bacillussubtilis) |
PF01266(DAO) | 3 | ALA A 325VAL A 204TRP A 205 | None | 0.87A | 1kqeA-3if9A:undetectable1kqeE-3if9A:undetectable | 1kqeA-3if9A:2.561kqeE-3if9A:2.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3irv | CYSTEINE HYDROLASE (Pseudomonassavastanoi) |
PF00857(Isochorismatase) | 3 | ALA A 228VAL A 41TRP A 43 | None | 0.89A | 1kqeA-3irvA:undetectable1kqeE-3irvA:undetectable | 1kqeA-3irvA:5.311kqeE-3irvA:5.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lml | LIN1278 PROTEIN (Listeriainnocua) |
PF04984(Phage_sheath_1)PF17481(Phage_sheath_1N)PF17482(Phage_sheath_1C) | 3 | ALA A 281VAL A 276TRP A 275 | None | 0.80A | 1kqeA-3lmlA:undetectable1kqeE-3lmlA:undetectable | 1kqeA-3lmlA:2.901kqeE-3lmlA:2.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m33 | UNCHARACTERIZEDPROTEIN (Deinococcusradiodurans) |
no annotation | 3 | ALA A 68VAL A 49TRP A 70 | None | 0.88A | 1kqeA-3m33A:undetectable1kqeE-3m33A:undetectable | 1kqeA-3m33A:3.481kqeE-3m33A:3.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mfn | UNCHARACTERIZEDPROTEIN (Dyadobacterfermentans) |
no annotation | 3 | ALA A 132VAL A 127TRP A 126 | None | 0.88A | 1kqeA-3mfnA:undetectable1kqeE-3mfnA:undetectable | 1kqeA-3mfnA:5.651kqeE-3mfnA:5.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3muo | PROLYL ENDOPEPTIDASE (Aeromonascaviae) |
PF00326(Peptidase_S9)PF02897(Peptidase_S9_N) | 3 | ALA A 50VAL A 45TRP A 44 | None | 0.88A | 1kqeA-3muoA:undetectable1kqeE-3muoA:undetectable | 1kqeA-3muoA:2.111kqeE-3muoA:2.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mz1 | PUTATIVETRANSCRIPTIONALREGULATOR (Sinorhizobiummeliloti) |
PF03466(LysR_substrate) | 3 | ALA A 290VAL A 285TRP A 284 | None | 0.81A | 1kqeA-3mz1A:undetectable1kqeE-3mz1A:undetectable | 1kqeA-3mz1A:2.141kqeE-3mz1A:2.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nqp | SUSD SUPERFAMILYPROTEIN (Bacteroidesfragilis) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 3 | ALA A 414VAL A 409TRP A 408 | None | 0.88A | 1kqeA-3nqpA:undetectable1kqeE-3nqpA:undetectable | 1kqeA-3nqpA:2.111kqeE-3nqpA:2.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3orj | SUGAR-BINDINGPROTEIN (Bacteroidesovatus) |
no annotation | 3 | ALA A 400VAL A 395TRP A 389 | None | 0.89A | 1kqeA-3orjA:undetectable1kqeE-3orjA:undetectable | 1kqeA-3orjA:3.121kqeE-3orjA:3.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qw2 | MYO-INOSITOL-1-PHOSPHATE SYNTHASE (INO1) (Archaeoglobusfulgidus) |
PF01658(Inos-1-P_synth)PF07994(NAD_binding_5) | 3 | ALA A 363VAL A 359TRP A 387 | None | 0.84A | 1kqeA-3qw2A:undetectable1kqeE-3qw2A:undetectable | 1kqeA-3qw2A:4.761kqeE-3qw2A:4.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r7p | RIBOSOMAL PROTEIN3/HOMINGENDONUCLEASE-LIKEFUSION PROTEIN (Leptographiumtruncatum) |
PF00961(LAGLIDADG_1) | 3 | ALA A 182VAL A 177TRP A 176 | None | 0.82A | 1kqeA-3r7pA:undetectable1kqeE-3r7pA:undetectable | 1kqeA-3r7pA:4.651kqeE-3r7pA:4.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vgl | GLUCOKINASE (Streptomycesgriseus) |
PF00480(ROK) | 3 | ALA A 73VAL A 75TRP A 83 | None | 0.79A | 1kqeA-3vglA:undetectable1kqeE-3vglA:undetectable | 1kqeA-3vglA:3.661kqeE-3vglA:3.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vgp | TRANSMEMBRANEOLIGOSACCHARYLTRANSFERASE,PUTATIVE (Archaeoglobusfulgidus) |
no annotation | 3 | ALA A 479VAL A 475TRP A 471 | None | 0.82A | 1kqeA-3vgpA:undetectable1kqeE-3vgpA:undetectable | 1kqeA-3vgpA:6.191kqeE-3vgpA:6.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vqr | PUTATIVEOXIDOREDUCTASE (Aeropyrumpernix) |
PF01266(DAO) | 3 | ALA A 374VAL A 232TRP A 233 | EDO A1003 ( 4.0A)ACT A1002 ( 3.3A)FAD A1001 (-4.7A) | 0.86A | 1kqeA-3vqrA:undetectable1kqeE-3vqrA:undetectable | 1kqeA-3vqrA:2.651kqeE-3vqrA:2.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wct | A1 GLOBIN CHAIN OFGIANT V2 HEMOGLOBIN (Lamellibrachiasatsuma) |
PF00042(Globin) | 3 | ALA A 113VAL A 115TRP A 128 | None | 0.89A | 1kqeA-3wctA:undetectable1kqeE-3wctA:undetectable | 1kqeA-3wctA:5.221kqeE-3wctA:5.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wrf | NON-REDUCING ENDBETA-L-ARABINOFURANOSIDASE (Bifidobacteriumlongum) |
PF07944(Glyco_hydro_127) | 3 | ALA A 593VAL A 602TRP A 469 | None | 0.82A | 1kqeA-3wrfA:undetectable1kqeE-3wrfA:undetectable | 1kqeA-3wrfA:1.901kqeE-3wrfA:1.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zxl | HIAXHD3 (Humicolainsolens) |
PF04616(Glyco_hydro_43) | 3 | ALA A 468VAL A 448TRP A 437 | None | 0.75A | 1kqeA-3zxlA:undetectable1kqeE-3zxlA:undetectable | 1kqeA-3zxlA:2.001kqeE-3zxlA:2.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4amc | GLUCANSUCRASE (Lactobacillusreuteri) |
PF01473(CW_binding_1)PF02324(Glyco_hydro_70) | 3 | ALA A1025VAL A1023TRP A1510 | None | 0.78A | 1kqeA-4amcA:undetectable1kqeE-4amcA:undetectable | 1kqeA-4amcA:3.861kqeE-4amcA:3.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ap3 | STEROIDMONOOXYGENASE (Rhodococcusrhodochrous) |
PF00743(FMO-like) | 3 | ALA A 467VAL A 462TRP A 461 | None | 0.86A | 1kqeA-4ap3A:undetectable1kqeE-4ap3A:undetectable | 1kqeA-4ap3A:11.111kqeE-4ap3A:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ayg | GLUCANSUCRASE (Lactobacillusreuteri) |
PF01473(CW_binding_1)PF02324(Glyco_hydro_70) | 3 | ALA A1026VAL A1024TRP A1505 | GOL A2791 (-3.6A)NoneNone | 0.73A | 1kqeA-4aygA:undetectable1kqeE-4aygA:undetectable | 1kqeA-4aygA:3.451kqeE-4aygA:3.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bzk | PROTEIN TRANSPORTPROTEIN SEC31 (Saccharomycescerevisiae) |
PF00400(WD40)PF12931(Sec16_C) | 3 | ALA A 173VAL A 175TRP A 217 | None | 0.76A | 1kqeA-4bzkA:undetectable1kqeE-4bzkA:undetectable | 1kqeA-4bzkA:1.091kqeE-4bzkA:1.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gxw | ADENOSINE DEAMINASE (Burkholderiaambifaria) |
PF00962(A_deaminase) | 3 | ALA A 10VAL A 8TRP A 279 | None | 0.80A | 1kqeA-4gxwA:undetectable1kqeE-4gxwA:undetectable | 1kqeA-4gxwA:3.321kqeE-4gxwA:3.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h2h | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME (Salipigerbermudensis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | ALA A 327VAL A 15TRP A 295 | None | 0.86A | 1kqeA-4h2hA:undetectable1kqeE-4h2hA:undetectable | 1kqeA-4h2hA:3.021kqeE-4h2hA:3.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4izg | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME,N-TERMINAL DOMAINPROTEIN (Paracoccusdenitrificans) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | ALA A 328VAL A 15TRP A 296 | None | 0.86A | 1kqeA-4izgA:undetectable1kqeE-4izgA:undetectable | 1kqeA-4izgA:5.591kqeE-4izgA:5.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jnd | CA(2+)/CALMODULIN-DEPENDENT PROTEINKINASE PHOSPHATASE (Caenorhabditiselegans) |
PF00481(PP2C) | 3 | ALA A 98VAL A 93TRP A 92 | None | 0.80A | 1kqeA-4jndA:undetectable1kqeE-4jndA:undetectable | 1kqeA-4jndA:2.131kqeE-4jndA:2.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lzh | L,D-TRANSPEPTIDASE (Klebsiellapneumoniae) |
PF03734(YkuD) | 3 | ALA A 168VAL A 170TRP A 149 | None | 0.84A | 1kqeA-4lzhA:undetectable1kqeE-4lzhA:undetectable | 1kqeA-4lzhA:7.871kqeE-4lzhA:7.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m8u | OLIGO-1,6-GLUCOSIDASE 1 (Bacillussubtilis) |
PF00128(Alpha-amylase)PF16657(Malt_amylase_C) | 3 | ALA A 200VAL A 100TRP A 172 | TRS A 601 ( 4.0A)NoneNone | 0.81A | 1kqeA-4m8uA:undetectable1kqeE-4m8uA:undetectable | 1kqeA-4m8uA:6.631kqeE-4m8uA:6.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mag | SIALIC ACID BINDINGPROTEIN (Vibrio cholerae) |
PF03480(DctP) | 3 | ALA A 65VAL A 214TRP A 120 | None | 0.75A | 1kqeA-4magA:undetectable1kqeE-4magA:undetectable | 1kqeA-4magA:4.051kqeE-4magA:4.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o7p | MALTOKINASE (Mycobacteriumtuberculosis) |
no annotation | 3 | ALA A 398VAL A 393TRP A 392 | None | 0.77A | 1kqeA-4o7pA:undetectable1kqeE-4o7pA:undetectable | 1kqeA-4o7pA:2.061kqeE-4o7pA:2.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4otm | SERINE/THREONINE-PROTEIN KINASE GCN2 (Saccharomycescerevisiae) |
PF12745(HGTP_anticodon2) | 3 | ALA A1566VAL A1561TRP A1560 | None | 0.77A | 1kqeA-4otmA:undetectable1kqeE-4otmA:undetectable | 1kqeA-4otmA:7.141kqeE-4otmA:7.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s38 | 4-HYDROXY-3-METHYLBUT-2-EN-1-YLDIPHOSPHATE SYNTHASE (Thermusthermophilus) |
PF04551(GcpE) | 3 | ALA A 219VAL A 214TRP A 213 | None | 0.81A | 1kqeA-4s38A:undetectable1kqeE-4s38A:undetectable | 1kqeA-4s38A:2.971kqeE-4s38A:2.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4trg | SIDC (Legionellapneumophila) |
no annotation | 3 | ALA A 316VAL A 318TRP A 323 | None | 0.81A | 1kqeA-4trgA:undetectable1kqeE-4trgA:undetectable | 1kqeA-4trgA:3.051kqeE-4trgA:3.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u98 | MALTOKINASE (Mycolicibacteriumvanbaalenii) |
PF01636(APH) | 3 | ALA A 385VAL A 380TRP A 379 | None | 0.75A | 1kqeA-4u98A:undetectable1kqeE-4u98A:undetectable | 1kqeA-4u98A:1.871kqeE-4u98A:1.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wrw | URACIL-DNAGLYCOSYLASE (Mycobacteriumtuberculosis) |
PF03167(UDG) | 3 | ALA A 52VAL A 49TRP A 145 | None | 0.86A | 1kqeA-4wrwA:undetectable1kqeE-4wrwA:undetectable | 1kqeA-4wrwA:8.641kqeE-4wrwA:8.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xhb | SIALIDASE B (Streptococcuspneumoniae) |
PF02012(BNR)PF02973(Sialidase)PF13088(BNR_2) | 3 | ALA A 241VAL A 306TRP A 308 | None | 0.76A | 1kqeA-4xhbA:undetectable1kqeE-4xhbA:undetectable | 1kqeA-4xhbA:1.441kqeE-4xhbA:1.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xwh | ALPHA-N-ACETYLGLUCOSAMINIDASE (Homo sapiens) |
PF05089(NAGLU)PF12971(NAGLU_N)PF12972(NAGLU_C) | 3 | ALA A 480VAL A 475TRP A 474 | None | 0.89A | 1kqeA-4xwhA:undetectable1kqeE-4xwhA:undetectable | 1kqeA-4xwhA:1.771kqeE-4xwhA:1.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z1p | CELL WALL SURFACEANCHOR PROTEIN (Streptococcusagalactiae) |
PF16364(Antigen_C) | 3 | ALA A 210VAL A 208TRP A 206 | None | 0.68A | 1kqeA-4z1pA:undetectable1kqeE-4z1pA:undetectable | 1kqeA-4z1pA:3.741kqeE-4z1pA:3.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z23 | CELL WALL SURFACEANCHOR PROTEIN (Streptococcusagalactiae) |
PF16364(Antigen_C) | 3 | ALA A 210VAL A 208TRP A 206 | None | 0.73A | 1kqeA-4z23A:undetectable1kqeE-4z23A:undetectable | 1kqeA-4z23A:3.741kqeE-4z23A:3.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zfm | PUTATIVE6-PHOSPHO-BETA-GALACTOBIOSIDASE (Geobacillusstearothermophilus) |
PF00232(Glyco_hydro_1) | 3 | ALA A 476VAL A 470TRP A 466 | None | 0.76A | 1kqeA-4zfmA:undetectable1kqeE-4zfmA:undetectable | 1kqeA-4zfmA:2.191kqeE-4zfmA:2.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a29 | EXOPOLYGALACTURONATELYASE (Vibriovulnificus) |
PF06917(Pectate_lyase_2) | 3 | ALA A 179VAL A 181TRP A 184 | None | 0.84A | 1kqeA-5a29A:undetectable1kqeE-5a29A:undetectable | 1kqeA-5a29A:2.751kqeE-5a29A:2.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bp1 | MYCOCEROSIC ACIDSYNTHASE (Mycolicibacteriumsmegmatis) |
PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 3 | ALA A 682VAL A 677TRP A 716 | None | 0.82A | 1kqeA-5bp1A:undetectable1kqeE-5bp1A:undetectable | 1kqeA-5bp1A:1.631kqeE-5bp1A:1.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cho | FLAVIN REDUCTASE (unculturedbacterium) |
PF01613(Flavin_Reduct) | 3 | ALA A 154VAL A 164TRP A 152 | None | 0.86A | 1kqeA-5choA:undetectable1kqeE-5choA:undetectable | 1kqeA-5choA:7.691kqeE-5choA:7.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5csu | 4-ALPHA-GLUCANOTRANSFERASE DPE1,CHLOROPLASTIC/AMYLOPLASTIC (Arabidopsisthaliana) |
PF02446(Glyco_hydro_77) | 3 | ALA A 383VAL A 326TRP A 338 | NoneNoneHMC A 606 ( 3.6A) | 0.82A | 1kqeA-5csuA:undetectable1kqeE-5csuA:undetectable | 1kqeA-5csuA:4.441kqeE-5csuA:4.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dgt | BENZOYLFORMATEDECARBOXYLASE (Pseudomonasputida) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 3 | ALA A 96VAL A 158TRP A 163 | None | 0.83A | 1kqeA-5dgtA:undetectable1kqeE-5dgtA:undetectable | 1kqeA-5dgtA:2.381kqeE-5dgtA:2.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g5u | BETA-HEXOSAMINIDASE (Pseudomonasaeruginosa) |
PF00933(Glyco_hydro_3) | 3 | ALA A 181VAL A 215TRP A 226 | None | 0.84A | 1kqeA-5g5uA:undetectable1kqeE-5g5uA:undetectable | 1kqeA-5g5uA:3.301kqeE-5g5uA:3.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gn5 | GLYCEROL KINASE (Trypanosomabrucei) |
PF00370(FGGY_N)PF02782(FGGY_C) | 3 | ALA A 461VAL A 464TRP A 465 | None | 0.87A | 1kqeA-5gn5A:undetectable1kqeE-5gn5A:undetectable | 1kqeA-5gn5A:1.561kqeE-5gn5A:1.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5irp | ALANINE RACEMASE 2 (Bacillussubtilis) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 3 | ALA A 157VAL A 152TRP A 163 | None | 0.85A | 1kqeA-5irpA:undetectable1kqeE-5irpA:undetectable | 1kqeA-5irpA:2.111kqeE-5irpA:2.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5na7 | PUTATIVEDIPEPTIDYL-PEPTIDASEIII (Bacteroidesthetaiotaomicron) |
no annotation | 3 | ALA A 549VAL A 544TRP A 543 | None | 0.77A | 1kqeA-5na7A:undetectable1kqeE-5na7A:undetectable | 1kqeA-5na7A:3.441kqeE-5na7A:3.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5njf | METALLOPROTEASE PMBA (Escherichiacoli) |
PF01523(PmbA_TldD) | 3 | ALA B 227VAL B 222TRP B 221 | None | 0.83A | 1kqeA-5njfB:undetectable1kqeE-5njfB:undetectable | 1kqeA-5njfB:2.411kqeE-5njfB:2.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nl7 | CALPONIN HOMOLOGYDOMAIN PROTEINPUTATIVE (Entamoebahistolytica) |
no annotation | 3 | ALA A 27VAL A 22TRP A 21 | None | 0.82A | 1kqeA-5nl7A:undetectable1kqeE-5nl7A:undetectable | 1kqeA-5nl7A:undetectable1kqeE-5nl7A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uxb | MACROLIDE2'-PHOSPHOTRANSFERASE MPHH (Brachybacteriumfaecium) |
PF01636(APH) | 3 | ALA A 77VAL A 212TRP A 215 | None | 0.83A | 1kqeA-5uxbA:undetectable1kqeE-5uxbA:undetectable | 1kqeA-5uxbA:4.021kqeE-5uxbA:4.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vm1 | XYLULOKINASE (Brucella ovis) |
PF00370(FGGY_N)PF02782(FGGY_C) | 3 | ALA A 141VAL A 136TRP A 135 | None | 0.85A | 1kqeA-5vm1A:undetectable1kqeE-5vm1A:undetectable | 1kqeA-5vm1A:5.701kqeE-5vm1A:5.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vwn | TRIOSEPHOSPHATEISOMERASE (Trichomonasvaginalis) |
no annotation | 3 | ALA A 193VAL A 191TRP A 152 | None | 0.74A | 1kqeA-5vwnA:undetectable1kqeE-5vwnA:undetectable | 1kqeA-5vwnA:undetectable1kqeE-5vwnA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z6v | ABC-TYPEUNCHARACTERIZEDTRANSPORT SYSTEMPERIPLASMICCOMPONENT-LIKEPROTEIN (Rhodothermusmarinus) |
no annotation | 3 | ALA A 144VAL A 146TRP A 148 | None | 0.88A | 1kqeA-5z6vA:undetectable1kqeE-5z6vA:undetectable | 1kqeA-5z6vA:undetectable1kqeE-5z6vA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f0q | PIZZA6-AYW (syntheticconstruct) |
no annotation | 3 | ALA A 23VAL A 20TRP A 237 | None | 0.89A | 1kqeA-6f0qA:undetectable1kqeE-6f0qA:undetectable | 1kqeA-6f0qA:undetectable1kqeE-6f0qA:undetectable |