SIMILAR PATTERNS OF AMINO ACIDS FOR 1KGL_A_RTLA175_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE


(Salmonella
enterica)
PF01739
(CheR)
PF03705
(CheR_N)
4 LEU A  93
ILE A  86
THR A  90
GLN A  83
None
None
SAH  A 287 (-3.5A)
None
1.18A 1kglA-1bc5A:
0.0
1kglA-1bc5A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gzj EGI

(Thermoascus
aurantiacus)
PF00150
(Cellulase)
4 ILE A 150
THR A 130
GLN A 147
MET A 183
None
1.19A 1kglA-1gzjA:
0.0
1kglA-1gzjA:
16.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1kqx CELLULAR
RETINOL-BINDING
PROTEIN


(Danio rerio)
PF00061
(Lipocalin)
4 LEU A  36
THR A  53
TRP A 106
GLN A 108
None
0.80A 1kglA-1kqxA:
24.3
1kglA-1kqxA:
59.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lpj RETINOL-BINDING
PROTEIN IV, CELLULAR


(Homo sapiens)
PF00061
(Lipocalin)
5 LEU A  36
ILE A  51
THR A  53
TRP A 106
MET A 119
None
0.51A 1kglA-1lpjA:
23.2
1kglA-1lpjA:
56.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lpj RETINOL-BINDING
PROTEIN IV, CELLULAR


(Homo sapiens)
PF00061
(Lipocalin)
4 LEU A  57
ILE A  51
THR A  53
TRP A 106
None
1.21A 1kglA-1lpjA:
23.2
1kglA-1lpjA:
56.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mx8 CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO


(Rattus
norvegicus)
PF00061
(Lipocalin)
4 LEU A  36
ILE A  51
THR A  53
MET A  62
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.6A)
RTL  A 135 ( 4.3A)
RTL  A 135 (-2.9A)
0.73A 1kglA-1mx8A:
19.5
1kglA-1mx8A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o9j ALDEHYDE
DEHYDROGENASE,
CYTOSOLIC 1


(Elephantulus
edwardii)
PF00171
(Aldedh)
4 LEU A 175
ILE A 345
THR A 197
GLN A 300
None
1.24A 1kglA-1o9jA:
0.0
1kglA-1o9jA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oh9 ACETYLGLUTAMATE
KINASE


(Escherichia
coli)
PF00696
(AA_kinase)
4 ILE A 256
THR A 254
MET A 196
MET A 214
None
None
None
ADP  A1259 (-4.5A)
1.20A 1kglA-1oh9A:
undetectable
1kglA-1oh9A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE


(Bacillus
subtilis)
PF01070
(FMN_dh)
4 LEU A 272
ILE A  58
THR A 277
MET A 279
None
1.28A 1kglA-1p0nA:
0.0
1kglA-1p0nA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pov POLIOVIRUS NATIVE
EMPTY CAPSID (TYPE
1)


(Enterovirus C)
PF00073
(Rhv)
PF02226
(Pico_P1A)
4 LEU 0 320
ILE 0  73
THR 0 276
MET 0 325
None
1.30A 1kglA-1pov0:
0.0
1kglA-1pov0:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rhc F420-DEPENDENT
ALCOHOL
DEHYDROGENASE


(Methanoculleus
thermophilus)
PF00296
(Bac_luciferase)
4 LEU A 170
THR A  74
GLN A  52
MET A  57
None
1.25A 1kglA-1rhcA:
undetectable
1kglA-1rhcA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rxm DNA POLYMERASE
SLIDING CLAMP


(Archaeoglobus
fulgidus)
PF00705
(PCNA_N)
PF02747
(PCNA_C)
4 LEU A 227
ILE A  74
THR A  15
MET A  71
None
1.26A 1kglA-1rxmA:
2.2
1kglA-1rxmA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s4e GALACTOKINASE

(Pyrococcus
furiosus)
PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C)
PF10509
(GalKase_gal_bdg)
4 LEU A 104
ILE A  94
THR A  35
TRP A  69
None
ADP  A 400 (-4.0A)
ADP  A 400 ( 4.4A)
ADP  A 400 (-4.2A)
1.30A 1kglA-1s4eA:
undetectable
1kglA-1s4eA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w2w 5-METHYLTHIORIBOSE-1
-PHOSPHATE ISOMERASE
5-METHYLTHIORIBOSE-1
-PHOSPHATE ISOMERASE


(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae)
PF01008
(IF-2B)
PF01008
(IF-2B)
4 LEU A 143
ILE B 282
THR B 316
MET A 154
None
1.29A 1kglA-1w2wA:
undetectable
1kglA-1w2wA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xkq SHORT-CHAIN
REDUCTASE FAMILY
MEMBER (5D234)


(Caenorhabditis
elegans)
PF13561
(adh_short_C2)
4 LEU A 169
ILE A 113
THR A 117
GLN A 109
None
1.23A 1kglA-1xkqA:
undetectable
1kglA-1xkqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z0x TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY


(Enterococcus
faecalis)
PF00440
(TetR_N)
PF02909
(TetR_C)
4 LEU A  78
ILE A 145
MET A 144
GLN A  90
None
1.10A 1kglA-1z0xA:
undetectable
1kglA-1z0xA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b0t NADP ISOCITRATE
DEHYDROGENASE


(Corynebacterium
glutamicum)
PF03971
(IDH)
4 LEU A 562
ILE A 528
THR A 402
MET A 400
None
1.10A 1kglA-2b0tA:
undetectable
1kglA-2b0tA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b81 LUCIFERASE-LIKE
MONOOXYGENASE


(Bacillus cereus)
PF00296
(Bac_luciferase)
4 LEU A 279
ILE A 247
MET A 215
TRP A  59
None
1.26A 1kglA-2b81A:
undetectable
1kglA-2b81A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dpn GLYCEROL KINASE

(Thermus
thermophilus)
PF00370
(FGGY_N)
PF02782
(FGGY_C)
4 LEU A   5
ILE A  50
THR A  54
GLN A  80
None
1.16A 1kglA-2dpnA:
undetectable
1kglA-2dpnA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dyu FORMAMIDASE

(Helicobacter
pylori)
PF00795
(CN_hydrolase)
4 LEU A 134
ILE A 103
THR A 117
GLN A  64
None
1.22A 1kglA-2dyuA:
1.3
1kglA-2dyuA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h8h PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC


(Homo sapiens)
PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr)
4 LEU A 108
ILE A 143
TRP A 148
GLN A 224
None
1.00A 1kglA-2h8hA:
undetectable
1kglA-2h8hA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h9f HYPOTHETICAL PROTEIN

(Pseudomonas
aeruginosa)
PF04303
(PrpF)
4 LEU A 334
ILE A 218
THR A 220
MET A 316
None
1.27A 1kglA-2h9fA:
undetectable
1kglA-2h9fA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j5t GLUTAMATE 5-KINASE

(Escherichia
coli)
PF00696
(AA_kinase)
PF01472
(PUA)
4 LEU A 166
ILE A 188
THR A 253
MET A 214
None
0.97A 1kglA-2j5tA:
undetectable
1kglA-2j5tA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mxd VIRAL PROTEIN
GENOME-LINKED


(Sapporo virus)
no annotation 4 LEU A1000
ILE A 963
MET A 970
GLN A 960
None
1.12A 1kglA-2mxdA:
undetectable
1kglA-2mxdA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2np0 BOTULINUM NEUROTOXIN
TYPE B


(Clostridium
botulinum)
PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N)
4 ILE A 963
THR A 950
TRP A 961
MET A 955
None
1.28A 1kglA-2np0A:
undetectable
1kglA-2np0A:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2owl RECOMBINATION-ASSOCI
ATED PROTEIN RDGC


(Escherichia
coli)
PF04381
(RdgC)
4 LEU A   7
ILE A 280
THR A 283
MET A   1
None
1.27A 1kglA-2owlA:
0.6
1kglA-2owlA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2po2 PROBABLE EXOSOME
COMPLEX EXONUCLEASE
2


(Pyrococcus
abyssi)
PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
4 LEU B  54
ILE B 221
THR B 197
MET B 217
None
1.18A 1kglA-2po2B:
undetectable
1kglA-2po2B:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pvz PRPF METHYLACONITATE
ISOMERASE


(Shewanella
oneidensis)
PF04303
(PrpF)
4 LEU A 338
ILE A 222
THR A 224
MET A 320
None
1.25A 1kglA-2pvzA:
0.1
1kglA-2pvzA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pyj DNA POLYMERASE

(Bacillus virus
phi29)
PF03175
(DNA_pol_B_2)
4 LEU A 328
ILE A 299
THR A 301
GLN A 446
None
1.29A 1kglA-2pyjA:
undetectable
1kglA-2pyjA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qyt 2-DEHYDROPANTOATE
2-REDUCTASE


(Porphyromonas
gingivalis)
PF02558
(ApbA)
PF08546
(ApbA_C)
4 LEU A 308
ILE A 216
THR A 209
GLN A 257
None
1.25A 1kglA-2qytA:
undetectable
1kglA-2qytA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT GAMMA


(Desulfovibrio
vulgaris)
PF04358
(DsrC)
4 LEU C  77
ILE C  50
MET C  95
GLN C  47
None
1.30A 1kglA-2v4jC:
undetectable
1kglA-2v4jC:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w21 GLUTAMATE 5-KINASE

(Escherichia
coli)
PF00696
(AA_kinase)
4 LEU A 166
ILE A 188
THR A 253
MET A 214
None
1.00A 1kglA-2w21A:
undetectable
1kglA-2w21A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wd5 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
3


(Mus musculus)
PF06470
(SMC_hinge)
4 LEU B 495
ILE B 504
THR B 500
MET B 536
None
1.05A 1kglA-2wd5B:
undetectable
1kglA-2wd5B:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2we5 CARBAMATE KINASE 1

(Enterococcus
faecalis)
PF00696
(AA_kinase)
4 LEU A  45
ILE A  14
TRP A  89
GLN A  54
None
1.00A 1kglA-2we5A:
undetectable
1kglA-2we5A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wtz UDP-N-ACETYLMURAMOYL
-L-ALANYL-D-GLUTAMAT
E--2,6-DIAMINOPIMELA
TE LIGASE


(Mycobacterium
tuberculosis)
PF01225
(Mur_ligase)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M)
4 LEU A 228
ILE A 178
THR A 196
MET A 219
None
None
UAG  A1498 (-4.7A)
None
1.16A 1kglA-2wtzA:
undetectable
1kglA-2wtzA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xmz HYDROLASE,
ALPHA/BETA HYDROLASE
FOLD FAMILY


(Staphylococcus
aureus)
PF00561
(Abhydrolase_1)
4 LEU A  20
ILE A 222
THR A 114
TRP A 198
None
1.29A 1kglA-2xmzA:
undetectable
1kglA-2xmzA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ycb CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR


(Methanothermobacter
thermautotrophicus)
PF07521
(RMMBL)
PF10996
(Beta-Casp)
PF16661
(Lactamase_B_6)
PF17214
(KH_7)
4 LEU A 610
ILE A 622
THR A 624
MET A 586
None
1.08A 1kglA-2ycbA:
undetectable
1kglA-2ycbA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yfs LEVANSUCRASE

(Lactobacillus
johnsonii)
PF02435
(Glyco_hydro_68)
4 ILE A 249
THR A 597
GLN A 658
MET A 655
None
1.26A 1kglA-2yfsA:
undetectable
1kglA-2yfsA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B


(Eptatretus
burgeri;
Mus musculus)
PF11921
(DUF3439)
PF13855
(LRR_8)
4 LEU B 251
THR B 302
MET B 331
GLN B 271
None
1.26A 1kglA-3a79B:
undetectable
1kglA-3a79B:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3af5 PUTATIVE
UNCHARACTERIZED
PROTEIN PH1404


(Pyrococcus
horikoshii)
PF07521
(RMMBL)
PF10996
(Beta-Casp)
PF16661
(Lactamase_B_6)
PF17214
(KH_7)
4 LEU A 625
ILE A 637
THR A 639
MET A 601
None
1.03A 1kglA-3af5A:
undetectable
1kglA-3af5A:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bn4 CARBON
DIOXIDE-CONCENTRATIN
G MECHANISM PROTEIN
CCMK HOMOLOG 1


(Synechocystis
sp.)
PF00936
(BMC)
4 LEU A  73
ILE A  77
GLN A  54
MET A  23
None
1.16A 1kglA-3bn4A:
undetectable
1kglA-3bn4A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dtz PUTATIVE CHLORITE
DISMUTASE TA0507


(Thermoplasma
acidophilum)
PF06778
(Chlor_dismutase)
4 LEU A 133
ILE A 202
MET A 125
MET A 143
None
1.23A 1kglA-3dtzA:
undetectable
1kglA-3dtzA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eo7 PUTATIVE
NITROREDUCTASE


(Trichormus
variabilis)
PF00881
(Nitroreductase)
4 LEU A 475
ILE A 480
THR A 505
GLN A 424
None
FMN  A 700 (-3.6A)
None
FMN  A 700 (-3.0A)
1.13A 1kglA-3eo7A:
undetectable
1kglA-3eo7A:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eoe PYRUVATE KINASE

(Toxoplasma
gondii)
PF00224
(PK)
PF02887
(PK_C)
4 LEU A 338
ILE A 310
THR A 341
MET A 315
None
1.24A 1kglA-3eoeA:
undetectable
1kglA-3eoeA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR CWF19


(Schizosaccharomyces
pombe)
no annotation 4 LEU c 437
ILE c 470
MET c 474
TRP c 568
None
1.16A 1kglA-3jb9c:
undetectable
1kglA-3jb9c:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k93 PHAGE RELATED
EXONUCLEASE


(Histophilus
somni)
no annotation 4 LEU A  73
ILE A 192
THR A 190
GLN A 151
None
1.24A 1kglA-3k93A:
undetectable
1kglA-3k93A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kbh ANGIOTENSIN-CONVERTI
NG ENZYME 2


(Homo sapiens)
PF01401
(Peptidase_M2)
4 LEU A 456
ILE A 446
THR A 449
GLN A 522
None
1.13A 1kglA-3kbhA:
undetectable
1kglA-3kbhA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kv0 HET-C2

(Podospora
anserina)
PF08718
(GLTP)
4 LEU A  79
ILE A  36
THR A  38
GLN A  89
MLY  A  76 ( 4.6A)
None
None
None
1.22A 1kglA-3kv0A:
undetectable
1kglA-3kv0A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lgx D-ALANINE--POLY(PHOS
PHORIBITOL) LIGASE
SUBUNIT 1


(Streptococcus
pyogenes)
PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
4 ILE A 236
THR A 238
MET A 186
MET A 172
None
0.67A 1kglA-3lgxA:
undetectable
1kglA-3lgxA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3or2 SULFITE REDCUTASE
SUBUNIT GAMA


(Desulfovibrio
gigas)
PF04358
(DsrC)
4 LEU C  77
ILE C  50
MET C  95
GLN C  47
None
1.26A 1kglA-3or2C:
undetectable
1kglA-3or2C:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p06 VP4 PROTEIN

(Tellina virus)
no annotation 4 LEU A 641
ILE A 691
THR A 713
TRP A 739
GOL  A 102 ( 4.5A)
None
None
None
1.23A 1kglA-3p06A:
undetectable
1kglA-3p06A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qc5 PLATELET BINDING
PROTEIN GSPB


(Streptococcus
gordonii)
no annotation 4 LEU X 373
THR X 382
GLN X 288
MET X 263
None
1.08A 1kglA-3qc5X:
2.1
1kglA-3qc5X:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3raz THIOREDOXIN-RELATED
PROTEIN


(Neisseria
meningitidis)
PF08534
(Redoxin)
4 ILE A  45
THR A 126
MET A  77
TRP A  66
None
1.21A 1kglA-3razA:
undetectable
1kglA-3razA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s4w FANCONI ANEMIA GROUP
D2 PROTEIN HOMOLOG


(Mus musculus)
PF14631
(FancD2)
4 LEU B 133
THR B 102
GLN B 157
MET B 170
None
1.11A 1kglA-3s4wB:
undetectable
1kglA-3s4wB:
7.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t7b ACETYLGLUTAMATE
KINASE


(Yersinia pestis)
PF00696
(AA_kinase)
4 ILE A 255
THR A 253
MET A 195
MET A 213
None
1.27A 1kglA-3t7bA:
undetectable
1kglA-3t7bA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ue1 PENICILLIN-BINDING
PROTEIN 1A


(Acinetobacter
baumannii)
PF00905
(Transpeptidase)
PF00912
(Transgly)
PF17092
(PCB_OB)
4 LEU A 666
ILE A 399
THR A 690
GLN A 397
None
1.23A 1kglA-3ue1A:
undetectable
1kglA-3ue1A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vla EDGP

(Daucus carota)
PF14541
(TAXi_C)
PF14543
(TAXi_N)
4 LEU A 257
ILE A 270
THR A 268
TRP A 341
NAG  A 601 ( 4.4A)
None
None
None
1.19A 1kglA-3vlaA:
undetectable
1kglA-3vlaA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wdg URACIL-DNA
GLYCOSYLASE
UNCHARACTERIZED
PROTEIN


(Staphylococcus
aureus;
Staphylococcus
aureus)
PF03167
(UDG)
PF06106
(SAUGI)
4 LEU B  77
ILE B  28
THR B  53
GLN A  58
None
1.29A 1kglA-3wdgB:
undetectable
1kglA-3wdgB:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4arv PHYTASE

(Yersinia
kristensenii)
PF00328
(His_Phos_2)
4 LEU A 209
ILE A 222
THR A 218
GLN A  26
None
EDO  A1417 (-4.7A)
EDO  A1417 (-4.2A)
None
1.15A 1kglA-4arvA:
undetectable
1kglA-4arvA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190


(Saccharomyces
cerevisiae)
PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4)
4 LEU A1622
THR A1617
GLN A1601
MET A1603
None
1.26A 1kglA-4c3hA:
undetectable
1kglA-4c3hA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c7v TRANSKETOLASE

(Lactobacillus
salivarius)
PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C)
4 LEU A 178
ILE A 216
THR A 242
GLN A 233
None
1.10A 1kglA-4c7vA:
undetectable
1kglA-4c7vA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4exk MALTOSE-BINDING
PERIPLASMIC PROTEIN,
UNCHARACTERIZED
PROTEIN CHIMERA


(Escherichia
coli;
Salmonella
enterica)
PF13416
(SBP_bac_8)
PF16583
(ZirS_C)
4 LEU A 304
ILE A 329
THR A  93
MET A 321
None
None
None
PGE  A 502 (-4.4A)
1.18A 1kglA-4exkA:
undetectable
1kglA-4exkA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ikm MALTOSE-BINDING
PERIPLASMIC PROTEIN,
CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 8


(Escherichia
coli;
Homo sapiens)
PF00619
(CARD)
PF13416
(SBP_bac_8)
4 LEU A 305
ILE A 330
THR A  94
MET A 322
TYI  A 308 ( 4.6A)
EDO  A 505 ( 4.9A)
None
None
1.25A 1kglA-4ikmA:
undetectable
1kglA-4ikmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4imd N-ACETYLNEURAMINATE
LYASE


(Pasteurella
multocida)
PF00701
(DHDPS)
4 LEU A 287
ILE A 219
THR A 238
MET A 193
None
1.14A 1kglA-4imdA:
undetectable
1kglA-4imdA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j3q CATECHOL OXIDASE

(Aspergillus
oryzae)
PF00264
(Tyrosinase)
4 LEU A 351
ILE A 109
THR A 114
GLN A 105
None
1.20A 1kglA-4j3qA:
undetectable
1kglA-4j3qA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jzy CRYPTOCHROME-1

(Drosophila
melanogaster)
PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7)
4 LEU A 287
ILE A 313
THR A 309
TRP A 141
None
1.16A 1kglA-4jzyA:
undetectable
1kglA-4jzyA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m0x CHLOROMUCONATE
CYCLOISOMERASE


(Rhodococcus
opacus)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 LEU A 278
ILE A   5
MET A   8
MET A  93
None
1.18A 1kglA-4m0xA:
undetectable
1kglA-4m0xA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mo9 PERIPLASMIC BINDING
PROTEIN


(Veillonella
parvula)
PF01497
(Peripla_BP_2)
4 LEU A  55
ILE A  92
MET A  67
MET A  86
None
1.21A 1kglA-4mo9A:
undetectable
1kglA-4mo9A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rcn LONG-CHAIN ACYL-COA
CARBOXYLASE


(Mycobacterium
avium)
PF00289
(Biotin_carb_N)
PF01039
(Carboxyl_trans)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2)
4 LEU A 306
ILE A 347
THR A 303
GLN A 246
None
1.30A 1kglA-4rcnA:
undetectable
1kglA-4rcnA:
7.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rye D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE


(Mycobacterium
tuberculosis)
PF00768
(Peptidase_S11)
4 ILE A  37
THR A 274
TRP A  45
MET A 256
None
1.22A 1kglA-4ryeA:
0.8
1kglA-4ryeA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ryf ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT


(Listeria
monocytogenes)
PF00574
(CLP_protease)
4 LEU H 126
ILE H 120
MET H 175
MET H 154
None
None
None
MLI  H 301 ( 4.6A)
0.86A 1kglA-4ryfH:
undetectable
1kglA-4ryfH:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yu9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE


(Homo sapiens)
PF04389
(Peptidase_M28)
4 LEU A 356
ILE A  62
THR A  60
MET A  65
None
0.99A 1kglA-4yu9A:
undetectable
1kglA-4yu9A:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a1n BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE


(Homo sapiens)
PF00043
(GST_C)
4 ILE A  99
THR A  98
TRP A 134
GLN A 137
None
1.28A 1kglA-5a1nA:
undetectable
1kglA-5a1nA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aor DOSAGE COMPENSATION
REGULATOR


(Drosophila
melanogaster)
PF00270
(DEAD)
PF00271
(Helicase_C)
PF04408
(HA2)
PF07717
(OB_NTP_bind)
4 LEU A 665
ILE A 719
THR A 717
GLN A 699
None
U  C   7 ( 3.9A)
U  C   7 ( 2.9A)
None
1.04A 1kglA-5aorA:
undetectable
1kglA-5aorA:
7.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aza MALTOSE-BINDING
PERIPLASMIC
PROTEIN,OLIGOSACCHAR
YL TRANSFERASE STT3
SUBUNIT RELATED
PROTEIN


(Escherichia
coli;
Pyrococcus
furiosus)
PF13416
(SBP_bac_8)
4 LEU A 816
ILE A 768
MET A 789
TRP A 458
None
1.13A 1kglA-5azaA:
undetectable
1kglA-5azaA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c59 MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB


(Escherichia
coli)
PF12704
(MacB_PCD)
4 LEU A 173
THR A 177
MET A 211
GLN A  96
None
1.25A 1kglA-5c59A:
undetectable
1kglA-5c59A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ej2 CARVEOL
DEHYDROGENASE


(Mycobacterium
avium)
PF13561
(adh_short_C2)
4 LEU A 207
ILE A 135
MET A 132
MET A 215
None
NAD  A 300 (-3.8A)
None
NAD  A 300 (-3.6A)
1.14A 1kglA-5ej2A:
undetectable
1kglA-5ej2A:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fhz ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3


(Homo sapiens)
PF00171
(Aldedh)
4 LEU A 187
ILE A 357
THR A 209
GLN A 312
None
1.29A 1kglA-5fhzA:
undetectable
1kglA-5fhzA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g3p FORMAMIDASE

(Bacillus cereus)
PF00795
(CN_hydrolase)
4 LEU A 133
ILE A 103
THR A 116
GLN A  64
None
1.17A 1kglA-5g3pA:
undetectable
1kglA-5g3pA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN


(Snake
atadenovirus A)
PF01696
(Adeno_E1B_55K)
4 LEU A 266
THR A 120
MET A 123
TRP A 126
None
GOL  A1374 (-3.1A)
GOL  A1374 ( 4.9A)
MMC  A1379 ( 3.4A)
1.24A 1kglA-5g5nA:
undetectable
1kglA-5g5nA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h7n NLRP12-PYD WITH MBP
TAG


(Homo sapiens)
PF02758
(PYRIN)
PF13416
(SBP_bac_8)
4 LEU A 305
ILE A 330
THR A  94
MET A 322
None
1.22A 1kglA-5h7nA:
undetectable
1kglA-5h7nA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hyh UNCHARACTERIZED
PROTEIN


(Streptomyces
venezuelae)
PF11583
(AurF)
4 LEU A 195
ILE A 206
THR A 202
MET A 323
None
1.07A 1kglA-5hyhA:
undetectable
1kglA-5hyhA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN


(Escherichia
coli;
Homo sapiens)
PF00100
(Zona_pellucida)
PF13416
(SBP_bac_8)
4 LEU A 671
ILE A 696
THR A 460
MET A 688
None
1.28A 1kglA-5hzvA:
undetectable
1kglA-5hzvA:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6s ENDOGLUCANASE

(Talaromyces
verruculosus)
PF00150
(Cellulase)
4 ILE A 159
THR A 139
GLN A 156
MET A 192
None
1.13A 1kglA-5i6sA:
undetectable
1kglA-5i6sA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jbg LGP2

(Gallus gallus)
PF00271
(Helicase_C)
PF04851
(ResIII)
PF11648
(RIG-I_C-RD)
4 LEU A 480
ILE A 293
THR A 296
GLN A 376
None
1.30A 1kglA-5jbgA:
undetectable
1kglA-5jbgA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k1s OXIDOREDUCTASE,
ZINC-BINDING
DEHYDROGENASE FAMILY


(Myxococcus
xanthus)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 LEU A 117
ILE A  69
GLN A  -2
MET A   1
None
1.05A 1kglA-5k1sA:
undetectable
1kglA-5k1sA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lc5 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4


(Bos taurus)
PF00361
(Proton_antipo_M)
PF01059
(Oxidored_q5_N)
4 LEU M 216
ILE M 270
THR M 272
TRP M 267
None
1.27A 1kglA-5lc5M:
undetectable
1kglA-5lc5M:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lxz SECRETED PROTEIN

(Streptomyces
lividans)
PF07646
(Kelch_2)
PF09118
(DUF1929)
4 LEU B 342
ILE B 409
THR B 395
MET B 384
None
1.30A 1kglA-5lxzB:
undetectable
1kglA-5lxzB:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m59 PRE-MRNA SPLICING
HELICASE-LIKE
PROTEIN


(Chaetomium
thermophilum)
PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63)
4 LEU A1947
ILE A1901
THR A1903
MET A1997
None
1.12A 1kglA-5m59A:
undetectable
1kglA-5m59A:
5.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nn7 URACIL-DNA
GLYCOSYLASE


(Human
gammaherpesvirus
8)
no annotation 4 LEU A  41
ILE A  52
GLN A  65
MET A  69
None
0.76A 1kglA-5nn7A:
undetectable
1kglA-5nn7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5or4 CATECHOL OXIDASE

(Aspergillus
oryzae)
no annotation 4 LEU A 351
ILE A 109
THR A 114
GLN A 105
None
1.13A 1kglA-5or4A:
undetectable
1kglA-5or4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ukh UNCHARACTERIZED
PROTEIN


(Streptococcus
intermedius)
no annotation 4 LEU A 341
ILE A 407
THR A 403
TRP A 287
None
1.21A 1kglA-5ukhA:
undetectable
1kglA-5ukhA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6anv ANTI-CRISPR PROTEIN
ACRF1 FUSED WITH
C-TERMINAL MBP TAG


(Escherichia
coli;
Pseudomonas
phage JBD30)
no annotation 4 LEU A 384
ILE A 409
THR A 173
MET A 401
None
1.16A 1kglA-6anvA:
undetectable
1kglA-6anvA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b4o GLUTATHIONE
REDUCTASE


(Enterococcus
faecalis)
no annotation 4 LEU A 181
ILE A 407
THR A 344
MET A 220
None
1.28A 1kglA-6b4oA:
undetectable
1kglA-6b4oA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c29 PUTATIVE METAL
RESISTANCE PROTEIN


(Proteus
mirabilis)
no annotation 4 LEU A   8
ILE A 119
THR A 121
TRP A  42
None
1.21A 1kglA-6c29A:
undetectable
1kglA-6c29A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfz ASK1
DAD2
HSK3


(Chaetomium
thermophilum;
Chaetomium
thermophilum;
Chaetomium
thermophilum)
no annotation
no annotation
no annotation
4 LEU A  50
ILE C  73
THR C  70
MET G  59
None
1.19A 1kglA-6cfzA:
undetectable
1kglA-6cfzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cl5 TAIL FIBER PROTEIN

(Pseudomonas
aeruginosa)
no annotation 4 ILE A 393
THR A 379
TRP A 436
GLN A 407
None
1.08A 1kglA-6cl5A:
undetectable
1kglA-6cl5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cl6 TAIL FIBER PROTEIN

(Pseudomonas
aeruginosa)
no annotation 4 ILE A 393
THR A 379
TRP A 436
GLN A 407
None
1.05A 1kglA-6cl6A:
undetectable
1kglA-6cl6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d9h CHIMERA PROTEIN OF
MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4 AND
ADENOSINE RECEPTOR
A1


(Homo sapiens)
no annotation 4 LEU R  65
ILE R  95
THR R  91
MET R 180
None
None
ADN  R 400 (-3.6A)
ADN  R 400 (-4.6A)
1.24A 1kglA-6d9hR:
undetectable
1kglA-6d9hR:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6emg G0S4M2

(Chaetomium
thermophilum)
no annotation 4 LEU A  58
MET A 193
TRP A 165
GLN A 187
None
1.26A 1kglA-6emgA:
undetectable
1kglA-6emgA:
undetectable