SIMILAR PATTERNS OF AMINO ACIDS FOR 1KGL_A_RTLA175_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bc5 | CHEMOTAXIS RECEPTORMETHYLTRANSFERASE (Salmonellaenterica) |
PF01739(CheR)PF03705(CheR_N) | 4 | LEU A 93ILE A 86THR A 90GLN A 83 | NoneNoneSAH A 287 (-3.5A)None | 1.18A | 1kglA-1bc5A:0.0 | 1kglA-1bc5A:17.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gzj | EGI (Thermoascusaurantiacus) |
PF00150(Cellulase) | 4 | ILE A 150THR A 130GLN A 147MET A 183 | None | 1.19A | 1kglA-1gzjA:0.0 | 1kglA-1gzjA:16.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1kqx | CELLULARRETINOL-BINDINGPROTEIN (Danio rerio) |
PF00061(Lipocalin) | 4 | LEU A 36THR A 53TRP A 106GLN A 108 | None | 0.80A | 1kglA-1kqxA:24.3 | 1kglA-1kqxA:59.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lpj | RETINOL-BINDINGPROTEIN IV, CELLULAR (Homo sapiens) |
PF00061(Lipocalin) | 5 | LEU A 36ILE A 51THR A 53TRP A 106MET A 119 | None | 0.51A | 1kglA-1lpjA:23.2 | 1kglA-1lpjA:56.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lpj | RETINOL-BINDINGPROTEIN IV, CELLULAR (Homo sapiens) |
PF00061(Lipocalin) | 4 | LEU A 57ILE A 51THR A 53TRP A 106 | None | 1.21A | 1kglA-1lpjA:23.2 | 1kglA-1lpjA:56.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1mx8 | CELLULARRETINOL-BINDINGPROTEIN I, HOLO (Rattusnorvegicus) |
PF00061(Lipocalin) | 4 | LEU A 36ILE A 51THR A 53MET A 62 | RTL A 135 ( 4.6A)RTL A 135 ( 4.6A)RTL A 135 ( 4.3A)RTL A 135 (-2.9A) | 0.73A | 1kglA-1mx8A:19.5 | 1kglA-1mx8A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o9j | ALDEHYDEDEHYDROGENASE,CYTOSOLIC 1 (Elephantulusedwardii) |
PF00171(Aldedh) | 4 | LEU A 175ILE A 345THR A 197GLN A 300 | None | 1.24A | 1kglA-1o9jA:0.0 | 1kglA-1o9jA:14.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oh9 | ACETYLGLUTAMATEKINASE (Escherichiacoli) |
PF00696(AA_kinase) | 4 | ILE A 256THR A 254MET A 196MET A 214 | NoneNoneNoneADP A1259 (-4.5A) | 1.20A | 1kglA-1oh9A:undetectable | 1kglA-1oh9A:17.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p0n | ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE (Bacillussubtilis) |
PF01070(FMN_dh) | 4 | LEU A 272ILE A 58THR A 277MET A 279 | None | 1.28A | 1kglA-1p0nA:0.0 | 1kglA-1p0nA:16.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pov | POLIOVIRUS NATIVEEMPTY CAPSID (TYPE1) (Enterovirus C) |
PF00073(Rhv)PF02226(Pico_P1A) | 4 | LEU 0 320ILE 0 73THR 0 276MET 0 325 | None | 1.30A | 1kglA-1pov0:0.0 | 1kglA-1pov0:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rhc | F420-DEPENDENTALCOHOLDEHYDROGENASE (Methanoculleusthermophilus) |
PF00296(Bac_luciferase) | 4 | LEU A 170THR A 74GLN A 52MET A 57 | None | 1.25A | 1kglA-1rhcA:undetectable | 1kglA-1rhcA:16.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rxm | DNA POLYMERASESLIDING CLAMP (Archaeoglobusfulgidus) |
PF00705(PCNA_N)PF02747(PCNA_C) | 4 | LEU A 227ILE A 74THR A 15MET A 71 | None | 1.26A | 1kglA-1rxmA:2.2 | 1kglA-1rxmA:17.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s4e | GALACTOKINASE (Pyrococcusfuriosus) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C)PF10509(GalKase_gal_bdg) | 4 | LEU A 104ILE A 94THR A 35TRP A 69 | NoneADP A 400 (-4.0A)ADP A 400 ( 4.4A)ADP A 400 (-4.2A) | 1.30A | 1kglA-1s4eA:undetectable | 1kglA-1s4eA:17.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w2w | 5-METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE5-METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE (Saccharomycescerevisiae;Saccharomycescerevisiae) |
PF01008(IF-2B)PF01008(IF-2B) | 4 | LEU A 143ILE B 282THR B 316MET A 154 | None | 1.29A | 1kglA-1w2wA:undetectable | 1kglA-1w2wA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xkq | SHORT-CHAINREDUCTASE FAMILYMEMBER (5D234) (Caenorhabditiselegans) |
PF13561(adh_short_C2) | 4 | LEU A 169ILE A 113THR A 117GLN A 109 | None | 1.23A | 1kglA-1xkqA:undetectable | 1kglA-1xkqA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z0x | TRANSCRIPTIONALREGULATOR, TETRFAMILY (Enterococcusfaecalis) |
PF00440(TetR_N)PF02909(TetR_C) | 4 | LEU A 78ILE A 145MET A 144GLN A 90 | None | 1.10A | 1kglA-1z0xA:undetectable | 1kglA-1z0xA:17.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b0t | NADP ISOCITRATEDEHYDROGENASE (Corynebacteriumglutamicum) |
PF03971(IDH) | 4 | LEU A 562ILE A 528THR A 402MET A 400 | None | 1.10A | 1kglA-2b0tA:undetectable | 1kglA-2b0tA:11.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b81 | LUCIFERASE-LIKEMONOOXYGENASE (Bacillus cereus) |
PF00296(Bac_luciferase) | 4 | LEU A 279ILE A 247MET A 215TRP A 59 | None | 1.26A | 1kglA-2b81A:undetectable | 1kglA-2b81A:18.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dpn | GLYCEROL KINASE (Thermusthermophilus) |
PF00370(FGGY_N)PF02782(FGGY_C) | 4 | LEU A 5ILE A 50THR A 54GLN A 80 | None | 1.16A | 1kglA-2dpnA:undetectable | 1kglA-2dpnA:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dyu | FORMAMIDASE (Helicobacterpylori) |
PF00795(CN_hydrolase) | 4 | LEU A 134ILE A 103THR A 117GLN A 64 | None | 1.22A | 1kglA-2dyuA:1.3 | 1kglA-2dyuA:15.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h8h | PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC (Homo sapiens) |
PF00017(SH2)PF00018(SH3_1)PF07714(Pkinase_Tyr) | 4 | LEU A 108ILE A 143TRP A 148GLN A 224 | None | 1.00A | 1kglA-2h8hA:undetectable | 1kglA-2h8hA:16.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h9f | HYPOTHETICAL PROTEIN (Pseudomonasaeruginosa) |
PF04303(PrpF) | 4 | LEU A 334ILE A 218THR A 220MET A 316 | None | 1.27A | 1kglA-2h9fA:undetectable | 1kglA-2h9fA:14.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j5t | GLUTAMATE 5-KINASE (Escherichiacoli) |
PF00696(AA_kinase)PF01472(PUA) | 4 | LEU A 166ILE A 188THR A 253MET A 214 | None | 0.97A | 1kglA-2j5tA:undetectable | 1kglA-2j5tA:17.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mxd | VIRAL PROTEINGENOME-LINKED (Sapporo virus) |
no annotation | 4 | LEU A1000ILE A 963MET A 970GLN A 960 | None | 1.12A | 1kglA-2mxdA:undetectable | 1kglA-2mxdA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2np0 | BOTULINUM NEUROTOXINTYPE B (Clostridiumbotulinum) |
PF01742(Peptidase_M27)PF07951(Toxin_R_bind_C)PF07952(Toxin_trans)PF07953(Toxin_R_bind_N) | 4 | ILE A 963THR A 950TRP A 961MET A 955 | None | 1.28A | 1kglA-2np0A:undetectable | 1kglA-2np0A:6.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2owl | RECOMBINATION-ASSOCIATED PROTEIN RDGC (Escherichiacoli) |
PF04381(RdgC) | 4 | LEU A 7ILE A 280THR A 283MET A 1 | None | 1.27A | 1kglA-2owlA:0.6 | 1kglA-2owlA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2po2 | PROBABLE EXOSOMECOMPLEX EXONUCLEASE2 (Pyrococcusabyssi) |
PF01138(RNase_PH)PF03725(RNase_PH_C) | 4 | LEU B 54ILE B 221THR B 197MET B 217 | None | 1.18A | 1kglA-2po2B:undetectable | 1kglA-2po2B:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pvz | PRPF METHYLACONITATEISOMERASE (Shewanellaoneidensis) |
PF04303(PrpF) | 4 | LEU A 338ILE A 222THR A 224MET A 320 | None | 1.25A | 1kglA-2pvzA:0.1 | 1kglA-2pvzA:18.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pyj | DNA POLYMERASE (Bacillus virusphi29) |
PF03175(DNA_pol_B_2) | 4 | LEU A 328ILE A 299THR A 301GLN A 446 | None | 1.29A | 1kglA-2pyjA:undetectable | 1kglA-2pyjA:13.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qyt | 2-DEHYDROPANTOATE2-REDUCTASE (Porphyromonasgingivalis) |
PF02558(ApbA)PF08546(ApbA_C) | 4 | LEU A 308ILE A 216THR A 209GLN A 257 | None | 1.25A | 1kglA-2qytA:undetectable | 1kglA-2qytA:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v4j | SULFITE REDUCTASE,DISSIMILATORY-TYPESUBUNIT GAMMA (Desulfovibriovulgaris) |
PF04358(DsrC) | 4 | LEU C 77ILE C 50MET C 95GLN C 47 | None | 1.30A | 1kglA-2v4jC:undetectable | 1kglA-2v4jC:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w21 | GLUTAMATE 5-KINASE (Escherichiacoli) |
PF00696(AA_kinase) | 4 | LEU A 166ILE A 188THR A 253MET A 214 | None | 1.00A | 1kglA-2w21A:undetectable | 1kglA-2w21A:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wd5 | STRUCTURALMAINTENANCE OFCHROMOSOMES PROTEIN3 (Mus musculus) |
PF06470(SMC_hinge) | 4 | LEU B 495ILE B 504THR B 500MET B 536 | None | 1.05A | 1kglA-2wd5B:undetectable | 1kglA-2wd5B:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2we5 | CARBAMATE KINASE 1 (Enterococcusfaecalis) |
PF00696(AA_kinase) | 4 | LEU A 45ILE A 14TRP A 89GLN A 54 | None | 1.00A | 1kglA-2we5A:undetectable | 1kglA-2we5A:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wtz | UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE (Mycobacteriumtuberculosis) |
PF01225(Mur_ligase)PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 4 | LEU A 228ILE A 178THR A 196MET A 219 | NoneNoneUAG A1498 (-4.7A)None | 1.16A | 1kglA-2wtzA:undetectable | 1kglA-2wtzA:10.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xmz | HYDROLASE,ALPHA/BETA HYDROLASEFOLD FAMILY (Staphylococcusaureus) |
PF00561(Abhydrolase_1) | 4 | LEU A 20ILE A 222THR A 114TRP A 198 | None | 1.29A | 1kglA-2xmzA:undetectable | 1kglA-2xmzA:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ycb | CLEAVAGE ANDPOLYADENYLATIONSPECIFICITY FACTOR (Methanothermobacterthermautotrophicus) |
PF07521(RMMBL)PF10996(Beta-Casp)PF16661(Lactamase_B_6)PF17214(KH_7) | 4 | LEU A 610ILE A 622THR A 624MET A 586 | None | 1.08A | 1kglA-2ycbA:undetectable | 1kglA-2ycbA:12.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yfs | LEVANSUCRASE (Lactobacillusjohnsonii) |
PF02435(Glyco_hydro_68) | 4 | ILE A 249THR A 597GLN A 658MET A 655 | None | 1.26A | 1kglA-2yfsA:undetectable | 1kglA-2yfsA:12.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a79 | TOLL-LIKE RECEPTOR6, VARIABLELYMPHOCYTE RECEPTORB (Eptatretusburgeri;Mus musculus) |
PF11921(DUF3439)PF13855(LRR_8) | 4 | LEU B 251THR B 302MET B 331GLN B 271 | None | 1.26A | 1kglA-3a79B:undetectable | 1kglA-3a79B:11.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3af5 | PUTATIVEUNCHARACTERIZEDPROTEIN PH1404 (Pyrococcushorikoshii) |
PF07521(RMMBL)PF10996(Beta-Casp)PF16661(Lactamase_B_6)PF17214(KH_7) | 4 | LEU A 625ILE A 637THR A 639MET A 601 | None | 1.03A | 1kglA-3af5A:undetectable | 1kglA-3af5A:12.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bn4 | CARBONDIOXIDE-CONCENTRATING MECHANISM PROTEINCCMK HOMOLOG 1 (Synechocystissp.) |
PF00936(BMC) | 4 | LEU A 73ILE A 77GLN A 54MET A 23 | None | 1.16A | 1kglA-3bn4A:undetectable | 1kglA-3bn4A:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dtz | PUTATIVE CHLORITEDISMUTASE TA0507 (Thermoplasmaacidophilum) |
PF06778(Chlor_dismutase) | 4 | LEU A 133ILE A 202MET A 125MET A 143 | None | 1.23A | 1kglA-3dtzA:undetectable | 1kglA-3dtzA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eo7 | PUTATIVENITROREDUCTASE (Trichormusvariabilis) |
PF00881(Nitroreductase) | 4 | LEU A 475ILE A 480THR A 505GLN A 424 | NoneFMN A 700 (-3.6A)NoneFMN A 700 (-3.0A) | 1.13A | 1kglA-3eo7A:undetectable | 1kglA-3eo7A:12.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eoe | PYRUVATE KINASE (Toxoplasmagondii) |
PF00224(PK)PF02887(PK_C) | 4 | LEU A 338ILE A 310THR A 341MET A 315 | None | 1.24A | 1kglA-3eoeA:undetectable | 1kglA-3eoeA:13.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jb9 | PRE-MRNA-SPLICINGFACTOR CWF19 (Schizosaccharomycespombe) |
no annotation | 4 | LEU c 437ILE c 470MET c 474TRP c 568 | None | 1.16A | 1kglA-3jb9c:undetectable | 1kglA-3jb9c:11.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k93 | PHAGE RELATEDEXONUCLEASE (Histophilussomni) |
no annotation | 4 | LEU A 73ILE A 192THR A 190GLN A 151 | None | 1.24A | 1kglA-3k93A:undetectable | 1kglA-3k93A:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kbh | ANGIOTENSIN-CONVERTING ENZYME 2 (Homo sapiens) |
PF01401(Peptidase_M2) | 4 | LEU A 456ILE A 446THR A 449GLN A 522 | None | 1.13A | 1kglA-3kbhA:undetectable | 1kglA-3kbhA:12.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kv0 | HET-C2 (Podosporaanserina) |
PF08718(GLTP) | 4 | LEU A 79ILE A 36THR A 38GLN A 89 | MLY A 76 ( 4.6A)NoneNoneNone | 1.22A | 1kglA-3kv0A:undetectable | 1kglA-3kv0A:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lgx | D-ALANINE--POLY(PHOSPHORIBITOL) LIGASESUBUNIT 1 (Streptococcuspyogenes) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | ILE A 236THR A 238MET A 186MET A 172 | None | 0.67A | 1kglA-3lgxA:undetectable | 1kglA-3lgxA:14.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3or2 | SULFITE REDCUTASESUBUNIT GAMA (Desulfovibriogigas) |
PF04358(DsrC) | 4 | LEU C 77ILE C 50MET C 95GLN C 47 | None | 1.26A | 1kglA-3or2C:undetectable | 1kglA-3or2C:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p06 | VP4 PROTEIN (Tellina virus) |
no annotation | 4 | LEU A 641ILE A 691THR A 713TRP A 739 | GOL A 102 ( 4.5A)NoneNoneNone | 1.23A | 1kglA-3p06A:undetectable | 1kglA-3p06A:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qc5 | PLATELET BINDINGPROTEIN GSPB (Streptococcusgordonii) |
no annotation | 4 | LEU X 373THR X 382GLN X 288MET X 263 | None | 1.08A | 1kglA-3qc5X:2.1 | 1kglA-3qc5X:14.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3raz | THIOREDOXIN-RELATEDPROTEIN (Neisseriameningitidis) |
PF08534(Redoxin) | 4 | ILE A 45THR A 126MET A 77TRP A 66 | None | 1.21A | 1kglA-3razA:undetectable | 1kglA-3razA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s4w | FANCONI ANEMIA GROUPD2 PROTEIN HOMOLOG (Mus musculus) |
PF14631(FancD2) | 4 | LEU B 133THR B 102GLN B 157MET B 170 | None | 1.11A | 1kglA-3s4wB:undetectable | 1kglA-3s4wB:7.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t7b | ACETYLGLUTAMATEKINASE (Yersinia pestis) |
PF00696(AA_kinase) | 4 | ILE A 255THR A 253MET A 195MET A 213 | None | 1.27A | 1kglA-3t7bA:undetectable | 1kglA-3t7bA:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ue1 | PENICILLIN-BINDINGPROTEIN 1A (Acinetobacterbaumannii) |
PF00905(Transpeptidase)PF00912(Transgly)PF17092(PCB_OB) | 4 | LEU A 666ILE A 399THR A 690GLN A 397 | None | 1.23A | 1kglA-3ue1A:undetectable | 1kglA-3ue1A:10.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vla | EDGP (Daucus carota) |
PF14541(TAXi_C)PF14543(TAXi_N) | 4 | LEU A 257ILE A 270THR A 268TRP A 341 | NAG A 601 ( 4.4A)NoneNoneNone | 1.19A | 1kglA-3vlaA:undetectable | 1kglA-3vlaA:14.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wdg | URACIL-DNAGLYCOSYLASEUNCHARACTERIZEDPROTEIN (Staphylococcusaureus;Staphylococcusaureus) |
PF03167(UDG)PF06106(SAUGI) | 4 | LEU B 77ILE B 28THR B 53GLN A 58 | None | 1.29A | 1kglA-3wdgB:undetectable | 1kglA-3wdgB:18.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4arv | PHYTASE (Yersiniakristensenii) |
PF00328(His_Phos_2) | 4 | LEU A 209ILE A 222THR A 218GLN A 26 | NoneEDO A1417 (-4.7A)EDO A1417 (-4.2A)None | 1.15A | 1kglA-4arvA:undetectable | 1kglA-4arvA:13.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c3h | DNA-DIRECTED RNAPOLYMERASE I SUBUNITRPA190 (Saccharomycescerevisiae) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 4 | LEU A1622THR A1617GLN A1601MET A1603 | None | 1.26A | 1kglA-4c3hA:undetectable | 1kglA-4c3hA:6.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c7v | TRANSKETOLASE (Lactobacillussalivarius) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 4 | LEU A 178ILE A 216THR A 242GLN A 233 | None | 1.10A | 1kglA-4c7vA:undetectable | 1kglA-4c7vA:12.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4exk | MALTOSE-BINDINGPERIPLASMIC PROTEIN,UNCHARACTERIZEDPROTEIN CHIMERA (Escherichiacoli;Salmonellaenterica) |
PF13416(SBP_bac_8)PF16583(ZirS_C) | 4 | LEU A 304ILE A 329THR A 93MET A 321 | NoneNoneNonePGE A 502 (-4.4A) | 1.18A | 1kglA-4exkA:undetectable | 1kglA-4exkA:13.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ikm | MALTOSE-BINDINGPERIPLASMIC PROTEIN,CASPASE RECRUITMENTDOMAIN-CONTAININGPROTEIN 8 (Escherichiacoli;Homo sapiens) |
PF00619(CARD)PF13416(SBP_bac_8) | 4 | LEU A 305ILE A 330THR A 94MET A 322 | TYI A 308 ( 4.6A)EDO A 505 ( 4.9A)NoneNone | 1.25A | 1kglA-4ikmA:undetectable | 1kglA-4ikmA:13.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4imd | N-ACETYLNEURAMINATELYASE (Pasteurellamultocida) |
PF00701(DHDPS) | 4 | LEU A 287ILE A 219THR A 238MET A 193 | None | 1.14A | 1kglA-4imdA:undetectable | 1kglA-4imdA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j3q | CATECHOL OXIDASE (Aspergillusoryzae) |
PF00264(Tyrosinase) | 4 | LEU A 351ILE A 109THR A 114GLN A 105 | None | 1.20A | 1kglA-4j3qA:undetectable | 1kglA-4j3qA:15.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jzy | CRYPTOCHROME-1 (Drosophilamelanogaster) |
PF00875(DNA_photolyase)PF03441(FAD_binding_7) | 4 | LEU A 287ILE A 313THR A 309TRP A 141 | None | 1.16A | 1kglA-4jzyA:undetectable | 1kglA-4jzyA:15.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m0x | CHLOROMUCONATECYCLOISOMERASE (Rhodococcusopacus) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 278ILE A 5MET A 8MET A 93 | None | 1.18A | 1kglA-4m0xA:undetectable | 1kglA-4m0xA:17.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mo9 | PERIPLASMIC BINDINGPROTEIN (Veillonellaparvula) |
PF01497(Peripla_BP_2) | 4 | LEU A 55ILE A 92MET A 67MET A 86 | None | 1.21A | 1kglA-4mo9A:undetectable | 1kglA-4mo9A:15.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rcn | LONG-CHAIN ACYL-COACARBOXYLASE (Mycobacteriumavium) |
PF00289(Biotin_carb_N)PF01039(Carboxyl_trans)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | LEU A 306ILE A 347THR A 303GLN A 246 | None | 1.30A | 1kglA-4rcnA:undetectable | 1kglA-4rcnA:7.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rye | D-ALANYL-D-ALANINECARBOXYPEPTIDASE (Mycobacteriumtuberculosis) |
PF00768(Peptidase_S11) | 4 | ILE A 37THR A 274TRP A 45MET A 256 | None | 1.22A | 1kglA-4ryeA:0.8 | 1kglA-4ryeA:17.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ryf | ATP-DEPENDENT CLPPROTEASE PROTEOLYTICSUBUNIT (Listeriamonocytogenes) |
PF00574(CLP_protease) | 4 | LEU H 126ILE H 120MET H 175MET H 154 | NoneNoneNoneMLI H 301 ( 4.6A) | 0.86A | 1kglA-4ryfH:undetectable | 1kglA-4ryfH:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yu9 | GLUTAMINYL-PEPTIDECYCLOTRANSFERASE (Homo sapiens) |
PF04389(Peptidase_M28) | 4 | LEU A 356ILE A 62THR A 60MET A 65 | None | 0.99A | 1kglA-4yu9A:undetectable | 1kglA-4yu9A:16.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a1n | BIFUNCTIONALGLUTAMATE/PROLINE--TRNA LIGASE (Homo sapiens) |
PF00043(GST_C) | 4 | ILE A 99THR A 98TRP A 134GLN A 137 | None | 1.28A | 1kglA-5a1nA:undetectable | 1kglA-5a1nA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aor | DOSAGE COMPENSATIONREGULATOR (Drosophilamelanogaster) |
PF00270(DEAD)PF00271(Helicase_C)PF04408(HA2)PF07717(OB_NTP_bind) | 4 | LEU A 665ILE A 719THR A 717GLN A 699 | None U C 7 ( 3.9A) U C 7 ( 2.9A)None | 1.04A | 1kglA-5aorA:undetectable | 1kglA-5aorA:7.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aza | MALTOSE-BINDINGPERIPLASMICPROTEIN,OLIGOSACCHARYL TRANSFERASE STT3SUBUNIT RELATEDPROTEIN (Escherichiacoli;Pyrococcusfuriosus) |
PF13416(SBP_bac_8) | 4 | LEU A 816ILE A 768MET A 789TRP A 458 | None | 1.13A | 1kglA-5azaA:undetectable | 1kglA-5azaA:9.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c59 | MACROLIDE EXPORTATP-BINDING/PERMEASEPROTEIN MACB (Escherichiacoli) |
PF12704(MacB_PCD) | 4 | LEU A 173THR A 177MET A 211GLN A 96 | None | 1.25A | 1kglA-5c59A:undetectable | 1kglA-5c59A:18.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ej2 | CARVEOLDEHYDROGENASE (Mycobacteriumavium) |
PF13561(adh_short_C2) | 4 | LEU A 207ILE A 135MET A 132MET A 215 | NoneNAD A 300 (-3.8A)NoneNAD A 300 (-3.6A) | 1.14A | 1kglA-5ej2A:undetectable | 1kglA-5ej2A:17.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fhz | ALDEHYDEDEHYDROGENASE FAMILY1 MEMBER A3 (Homo sapiens) |
PF00171(Aldedh) | 4 | LEU A 187ILE A 357THR A 209GLN A 312 | None | 1.29A | 1kglA-5fhzA:undetectable | 1kglA-5fhzA:13.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g3p | FORMAMIDASE (Bacillus cereus) |
PF00795(CN_hydrolase) | 4 | LEU A 133ILE A 103THR A 116GLN A 64 | None | 1.17A | 1kglA-5g3pA:undetectable | 1kglA-5g3pA:14.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g5n | LH3HEXON-INTERLACINGCAPSID PROTEIN (Snakeatadenovirus A) |
PF01696(Adeno_E1B_55K) | 4 | LEU A 266THR A 120MET A 123TRP A 126 | NoneGOL A1374 (-3.1A)GOL A1374 ( 4.9A)MMC A1379 ( 3.4A) | 1.24A | 1kglA-5g5nA:undetectable | 1kglA-5g5nA:16.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h7n | NLRP12-PYD WITH MBPTAG (Homo sapiens) |
PF02758(PYRIN)PF13416(SBP_bac_8) | 4 | LEU A 305ILE A 330THR A 94MET A 322 | None | 1.22A | 1kglA-5h7nA:undetectable | 1kglA-5h7nA:13.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hyh | UNCHARACTERIZEDPROTEIN (Streptomycesvenezuelae) |
PF11583(AurF) | 4 | LEU A 195ILE A 206THR A 202MET A 323 | None | 1.07A | 1kglA-5hyhA:undetectable | 1kglA-5hyhA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hzv | MALTOSE-BINDINGPERIPLASMICPROTEIN,ENDOGLIN (Escherichiacoli;Homo sapiens) |
PF00100(Zona_pellucida)PF13416(SBP_bac_8) | 4 | LEU A 671ILE A 696THR A 460MET A 688 | None | 1.28A | 1kglA-5hzvA:undetectable | 1kglA-5hzvA:11.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i6s | ENDOGLUCANASE (Talaromycesverruculosus) |
PF00150(Cellulase) | 4 | ILE A 159THR A 139GLN A 156MET A 192 | None | 1.13A | 1kglA-5i6sA:undetectable | 1kglA-5i6sA:14.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jbg | LGP2 (Gallus gallus) |
PF00271(Helicase_C)PF04851(ResIII)PF11648(RIG-I_C-RD) | 4 | LEU A 480ILE A 293THR A 296GLN A 376 | None | 1.30A | 1kglA-5jbgA:undetectable | 1kglA-5jbgA:11.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k1s | OXIDOREDUCTASE,ZINC-BINDINGDEHYDROGENASE FAMILY (Myxococcusxanthus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | LEU A 117ILE A 69GLN A -2MET A 1 | None | 1.05A | 1kglA-5k1sA:undetectable | 1kglA-5k1sA:16.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lc5 | NADH-UBIQUINONEOXIDOREDUCTASE CHAIN4 (Bos taurus) |
PF00361(Proton_antipo_M)PF01059(Oxidored_q5_N) | 4 | LEU M 216ILE M 270THR M 272TRP M 267 | None | 1.27A | 1kglA-5lc5M:undetectable | 1kglA-5lc5M:13.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lxz | SECRETED PROTEIN (Streptomyceslividans) |
PF07646(Kelch_2)PF09118(DUF1929) | 4 | LEU B 342ILE B 409THR B 395MET B 384 | None | 1.30A | 1kglA-5lxzB:undetectable | 1kglA-5lxzB:11.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m59 | PRE-MRNA SPLICINGHELICASE-LIKEPROTEIN (Chaetomiumthermophilum) |
PF00270(DEAD)PF00271(Helicase_C)PF02889(Sec63) | 4 | LEU A1947ILE A1901THR A1903MET A1997 | None | 1.12A | 1kglA-5m59A:undetectable | 1kglA-5m59A:5.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nn7 | URACIL-DNAGLYCOSYLASE (Humangammaherpesvirus8) |
no annotation | 4 | LEU A 41ILE A 52GLN A 65MET A 69 | None | 0.76A | 1kglA-5nn7A:undetectable | 1kglA-5nn7A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5or4 | CATECHOL OXIDASE (Aspergillusoryzae) |
no annotation | 4 | LEU A 351ILE A 109THR A 114GLN A 105 | None | 1.13A | 1kglA-5or4A:undetectable | 1kglA-5or4A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ukh | UNCHARACTERIZEDPROTEIN (Streptococcusintermedius) |
no annotation | 4 | LEU A 341ILE A 407THR A 403TRP A 287 | None | 1.21A | 1kglA-5ukhA:undetectable | 1kglA-5ukhA:17.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6anv | ANTI-CRISPR PROTEINACRF1 FUSED WITHC-TERMINAL MBP TAG (Escherichiacoli;Pseudomonasphage JBD30) |
no annotation | 4 | LEU A 384ILE A 409THR A 173MET A 401 | None | 1.16A | 1kglA-6anvA:undetectable | 1kglA-6anvA:13.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b4o | GLUTATHIONEREDUCTASE (Enterococcusfaecalis) |
no annotation | 4 | LEU A 181ILE A 407THR A 344MET A 220 | None | 1.28A | 1kglA-6b4oA:undetectable | 1kglA-6b4oA:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c29 | PUTATIVE METALRESISTANCE PROTEIN (Proteusmirabilis) |
no annotation | 4 | LEU A 8ILE A 119THR A 121TRP A 42 | None | 1.21A | 1kglA-6c29A:undetectable | 1kglA-6c29A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfz | ASK1DAD2HSK3 (Chaetomiumthermophilum;Chaetomiumthermophilum;Chaetomiumthermophilum) |
no annotationno annotationno annotation | 4 | LEU A 50ILE C 73THR C 70MET G 59 | None | 1.19A | 1kglA-6cfzA:undetectable | 1kglA-6cfzA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cl5 | TAIL FIBER PROTEIN (Pseudomonasaeruginosa) |
no annotation | 4 | ILE A 393THR A 379TRP A 436GLN A 407 | None | 1.08A | 1kglA-6cl5A:undetectable | 1kglA-6cl5A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cl6 | TAIL FIBER PROTEIN (Pseudomonasaeruginosa) |
no annotation | 4 | ILE A 393THR A 379TRP A 436GLN A 407 | None | 1.05A | 1kglA-6cl6A:undetectable | 1kglA-6cl6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d9h | CHIMERA PROTEIN OFMUSCARINICACETYLCHOLINERECEPTOR M4 ANDADENOSINE RECEPTORA1 (Homo sapiens) |
no annotation | 4 | LEU R 65ILE R 95THR R 91MET R 180 | NoneNoneADN R 400 (-3.6A)ADN R 400 (-4.6A) | 1.24A | 1kglA-6d9hR:undetectable | 1kglA-6d9hR:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6emg | G0S4M2 (Chaetomiumthermophilum) |
no annotation | 4 | LEU A 58MET A 193TRP A 165GLN A 187 | None | 1.26A | 1kglA-6emgA:undetectable | 1kglA-6emgA:undetectable |