SIMILAR PATTERNS OF AMINO ACIDS FOR 1JIP_A_KTNA801_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dj3 | ADENYLOSUCCINATESYNTHETASE (Triticumaestivum) |
PF00709(Adenylsucc_synt) | 5 | GLY A 99LEU A 78ARG A 114LEU A 70ALA A 69 | None | 1.29A | 1jipA-1dj3A:0.0 | 1jipA-1dj3A:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fc4 | 2-AMINO-3-KETOBUTYRATE CONENZYME ALIGASE (Escherichiacoli) |
PF00155(Aminotran_1_2) | 5 | PHE A 309GLY A 188LEU A 53ALA A 214LEU A 302 | None | 0.98A | 1jipA-1fc4A:0.0 | 1jipA-1fc4A:23.98 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jio | CYTOCHROME P450107A1 (Saccharopolysporaerythraea) |
PF00067(p450) | 7 | ALA A 74GLY A 91LEU A 175ARG A 185VAL A 237ALA A 241LEU A 391 | DEB A 420 (-3.8A)HEM A 410 ( 3.1A)NoneDEB A 420 ( 4.6A)DEB A 420 ( 4.3A)DEB A 420 ( 3.6A)DEB A 420 ( 4.8A) | 0.51A | 1jipA-1jioA:68.9 | 1jipA-1jioA:99.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jio | CYTOCHROME P450107A1 (Saccharopolysporaerythraea) |
PF00067(p450) | 6 | ALA A 74LEU A 175ARG A 185ALA A 245THR A 292LEU A 391 | DEB A 420 (-3.8A)NoneDEB A 420 ( 4.6A)HEM A 410 (-3.5A)NoneDEB A 420 ( 4.8A) | 1.26A | 1jipA-1jioA:68.9 | 1jipA-1jioA:99.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jio | CYTOCHROME P450107A1 (Saccharopolysporaerythraea) |
PF00067(p450) | 9 | ALA A 74TYR A 75GLY A 91THR A 92LEU A 175ARG A 185VAL A 237THR A 292LEU A 391 | DEB A 420 (-3.8A)DEB A 420 ( 4.8A)HEM A 410 ( 3.1A)DEB A 420 (-4.2A)NoneDEB A 420 ( 4.6A)DEB A 420 ( 4.3A)NoneDEB A 420 ( 4.8A) | 0.21A | 1jipA-1jioA:68.9 | 1jipA-1jioA:99.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jio | CYTOCHROME P450107A1 (Saccharopolysporaerythraea) |
PF00067(p450) | 5 | ALA A 74TYR A 75LEU A 392VAL A 237LEU A 391 | DEB A 420 (-3.8A)DEB A 420 ( 4.8A)DEB A 420 (-3.6A)DEB A 420 ( 4.3A)DEB A 420 ( 4.8A) | 1.29A | 1jipA-1jioA:68.9 | 1jipA-1jioA:99.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jio | CYTOCHROME P450107A1 (Saccharopolysporaerythraea) |
PF00067(p450) | 7 | GLY A 91LEU A 175ARG A 185VAL A 237LEU A 240ALA A 241LEU A 391 | HEM A 410 ( 3.1A)NoneDEB A 420 ( 4.6A)DEB A 420 ( 4.3A)DEB A 420 ( 4.5A)DEB A 420 ( 3.6A)DEB A 420 ( 4.8A) | 0.69A | 1jipA-1jioA:68.9 | 1jipA-1jioA:99.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jio | CYTOCHROME P450107A1 (Saccharopolysporaerythraea) |
PF00067(p450) | 6 | PHE A 72ALA A 74LEU A 175ARG A 185ALA A 245LEU A 391 | NoneDEB A 420 (-3.8A)NoneDEB A 420 ( 4.6A)HEM A 410 (-3.5A)DEB A 420 ( 4.8A) | 1.29A | 1jipA-1jioA:68.9 | 1jipA-1jioA:99.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jio | CYTOCHROME P450107A1 (Saccharopolysporaerythraea) |
PF00067(p450) | 6 | PHE A 72ALA A 74TYR A 75LEU A 175ARG A 185LEU A 391 | NoneDEB A 420 (-3.8A)DEB A 420 ( 4.8A)NoneDEB A 420 ( 4.6A)DEB A 420 ( 4.8A) | 0.75A | 1jipA-1jioA:68.9 | 1jipA-1jioA:99.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jio | CYTOCHROME P450107A1 (Saccharopolysporaerythraea) |
PF00067(p450) | 6 | PHE A 72TYR A 75LEU A 175ARG A 185LEU A 240LEU A 391 | NoneDEB A 420 ( 4.8A)NoneDEB A 420 ( 4.6A)DEB A 420 ( 4.5A)DEB A 420 ( 4.8A) | 0.76A | 1jipA-1jioA:68.9 | 1jipA-1jioA:99.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jio | CYTOCHROME P450107A1 (Saccharopolysporaerythraea) |
PF00067(p450) | 8 | TYR A 75GLY A 91THR A 92LEU A 175ARG A 185VAL A 237LEU A 240LEU A 391 | DEB A 420 ( 4.8A)HEM A 410 ( 3.1A)DEB A 420 (-4.2A)NoneDEB A 420 ( 4.6A)DEB A 420 ( 4.3A)DEB A 420 ( 4.5A)DEB A 420 ( 4.8A) | 0.43A | 1jipA-1jioA:68.9 | 1jipA-1jioA:99.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kwc | 2,3-DIHYDROXYBIPHENYL DIOXYGENASE (Pseudomonas sp.KKS102) |
PF00903(Glyoxalase) | 5 | PHE B 10ALA B 50GLY B 6ALA B 120LEU B 39 | None | 1.19A | 1jipA-1kwcB:0.6 | 1jipA-1kwcB:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l8j | ENDOTHELIAL PROTEINC RECEPTOR (Homo sapiens) |
PF16497(MHC_I_3) | 5 | ALA A 135LEU A 151VAL A 118THR A 140LEU A 148 | None | 1.18A | 1jipA-1l8jA:undetectable | 1jipA-1l8jA:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m9u | EARTHWORMFIBRINOLYTIC ENZYME (Eisenia fetida) |
PF00089(Trypsin) | 5 | ALA A 83GLY A 69THR A 80LEU A 106LEU A 108 | None | 1.19A | 1jipA-1m9uA:0.0 | 1jipA-1m9uA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rqg | METHIONYL-TRNASYNTHETASE (Pyrococcusabyssi) |
PF08264(Anticodon_1)PF09334(tRNA-synt_1g) | 5 | PHE A 465ALA A 463LEU A 396LEU A 456LEU A 400 | None | 1.25A | 1jipA-1rqgA:2.2 | 1jipA-1rqgA:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u7g | PROBABLE AMMONIUMTRANSPORTER (Escherichiacoli) |
PF00909(Ammonium_transp) | 5 | ALA A 377VAL A 116LEU A 119ALA A 120LEU A 383 | None | 1.38A | 1jipA-1u7gA:0.5 | 1jipA-1u7gA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w1k | VANILLYL-ALCOHOLOXIDASE (Penicilliumsimplicissimum) |
PF01565(FAD_binding_4)PF02913(FAD-oxidase_C) | 5 | PHE A 353THR A 457LEU A 346ALA A 319LEU A 348 | None | 1.33A | 1jipA-1w1kA:0.0 | 1jipA-1w1kA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y2f | CELL DIVISIONPROTEIN ZIPA (Escherichiacoli) |
PF04354(ZipA_C) | 5 | GLY A 40LEU A 28LEU A 61ALA A 62LEU A 29 | NoneNoneNoneWAI A 300 (-3.5A)None | 1.12A | 1jipA-1y2fA:undetectable | 1jipA-1y2fA:15.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z87 | ALPHA-1-SYNTROPHIN (Mus musculus) |
PF00595(PDZ) | 5 | GLY A 263THR A 264LEU A 33ALA A 255LEU A 40 | GLY A 263 ( 0.0A)THR A 264 ( 0.8A)LEU A 33 ( 0.6A)ALA A 255 ( 0.0A)LEU A 40 ( 0.6A) | 1.32A | 1jipA-1z87A:undetectable | 1jipA-1z87A:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ay9 | AROMATIC AMINO ACIDAMINOTRANSFERASE (Paracoccusdenitrificans) |
PF00155(Aminotran_1_2) | 5 | ALA A 115GLY A 268THR A 105LEU A 187LEU A 220 | None | 0.91A | 1jipA-2ay9A:undetectable | 1jipA-2ay9A:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hj0 | PUTATIVE CITRATELYASE, ALFA SUBUNIT (Streptococcusmutans) |
PF04223(CitF) | 5 | PHE A 405ALA A 404GLY A 149ALA A 396LEU A 372 | NoneNoneNoneCIT A 601 (-2.9A)None | 1.44A | 1jipA-2hj0A:undetectable | 1jipA-2hj0A:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hsi | PUTATIVE PEPTIDASEM23 (Pseudomonasaeruginosa) |
PF01551(Peptidase_M23) | 5 | PHE A 100GLY A 37LEU A 30ALA A 274LEU A 31 | None | 1.39A | 1jipA-2hsiA:undetectable | 1jipA-2hsiA:23.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nlz | CEPHALOSPORINACYLASE (Bacillushalodurans) |
PF01019(G_glu_transpept) | 5 | ALA A 34GLY A 527THR A 528LEU A 41ALA A 21 | None | 1.44A | 1jipA-2nlzA:0.6 | 1jipA-2nlzA:24.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q5o | PHENYLPYRUVATEDECARBOXYLASE (Azospirillumbrasilense) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | PHE A 301ALA A 300VAL A 222LEU A 225ALA A 226 | None | 0.94A | 1jipA-2q5oA:undetectable | 1jipA-2q5oA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qec | HISTONEACETYLTRANSFERASEHPA2 AND RELATEDACETYLTRANSFERASES (Corynebacteriumglutamicum) |
PF00583(Acetyltransf_1) | 5 | GLY A 138LEU A 174VAL A 141ALA A 144LEU A 170 | EDO A 211 (-3.3A)NoneNoneNoneNone | 1.44A | 1jipA-2qecA:undetectable | 1jipA-2qecA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rgj | FLAVIN-CONTAININGMONOOXYGENASE (Pseudomonasaeruginosa) |
PF01494(FAD_binding_3) | 5 | ALA A 125GLY A 29LEU A 21ALA A 22LEU A 33 | None | 1.05A | 1jipA-2rgjA:undetectable | 1jipA-2rgjA:24.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vro | ALDEHYDEDEHYDROGENASE (Paraburkholderiaxenovorans) |
PF00171(Aldedh) | 5 | GLY A 105LEU A 204LEU A 69THR A 191LEU A 209 | None | 1.18A | 1jipA-2vroA:undetectable | 1jipA-2vroA:24.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wt9 | NICOTINAMIDASE (Acinetobacterbaumannii) |
PF00857(Isochorismatase) | 5 | THR A 163LEU A 210VAL A 13LEU A 12ALA A 11 | None | 0.93A | 1jipA-2wt9A:undetectable | 1jipA-2wt9A:19.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yy9 | ZINC FINGER AND BTBDOMAIN-CONTAININGPROTEIN 48 (Mus musculus) |
PF00651(BTB) | 5 | ALA A 39GLY A 74VAL A 32LEU A 65LEU A 44 | None | 1.21A | 1jipA-2yy9A:undetectable | 1jipA-2yy9A:17.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bdz | P450CIN (Citrobacterbraakii) |
PF00067(p450) | 5 | PHE A 246ALA A 242GLY A 341LEU A 237ALA A 91 | HEM A 450 (-4.9A)HEM A 450 (-3.5A)HEM A 450 (-4.1A)MLI A 500 ( 4.5A)MLI A 500 ( 2.9A) | 1.42A | 1jipA-3bdzA:45.7 | 1jipA-3bdzA:29.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bjb | PROBABLETRANSCRIPTIONALREGULATOR, TETRFAMILY PROTEIN (Rhodococcusjostii) |
PF00440(TetR_N) | 5 | ALA A 50GLY A 55THR A 56LEU A 32LEU A 67 | NoneSO4 A 319 (-3.2A)SO4 A 320 (-2.8A)NoneNone | 1.29A | 1jipA-3bjbA:undetectable | 1jipA-3bjbA:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cvg | PUTATIVE METALBINDING PROTEIN (Coccidioidesimmitis) |
PF12849(PBP_like_2) | 5 | ALA A 255TYR A 99GLY A 43VAL A 53LEU A 52 | None | 1.23A | 1jipA-3cvgA:undetectable | 1jipA-3cvgA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g5s | METHYLENETETRAHYDROFOLATE--TRNA-(URACIL-5-)-METHYLTRANSFERASE TRMFO (Thermusthermophilus) |
PF01134(GIDA) | 5 | GLY A 354LEU A 313LEU A 131ALA A 132LEU A 319 | None | 1.11A | 1jipA-3g5sA:undetectable | 1jipA-3g5sA:23.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h84 | ATPASE GET3 (Saccharomycescerevisiae) |
PF02374(ArsA_ATPase) | 5 | ALA A 139GLY A 131LEU A 120ALA A 125LEU A 219 | None | 1.32A | 1jipA-3h84A:undetectable | 1jipA-3h84A:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hz6 | XYLULOKINASE (Chromobacteriumviolaceum) |
PF00370(FGGY_N)PF02782(FGGY_C) | 5 | TYR A 100GLY A 11THR A 12LEU A 287ALA A 245 | GOL A 513 (-3.4A)NoneGOL A 513 (-4.1A)NoneNone | 1.38A | 1jipA-3hz6A:undetectable | 1jipA-3hz6A:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ide | CAPSID PROTEIN VP2 (Infectiouspancreaticnecrosis virus) |
PF01766(Birna_VP2) | 5 | GLY A 20THR A 19LEU A 166LEU A 11LEU A 164 | None | 1.39A | 1jipA-3ideA:undetectable | 1jipA-3ideA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k0s | DNA MISMATCH REPAIRPROTEIN MUTS (Escherichiacoli) |
PF00488(MutS_V)PF01624(MutS_I)PF05188(MutS_II)PF05190(MutS_IV)PF05192(MutS_III) | 5 | LEU A 632LEU A 295ALA A 292THR A 622LEU A 629 | NoneNoneNoneADP A1801 (-3.2A)None | 1.40A | 1jipA-3k0sA:1.2 | 1jipA-3k0sA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mpn | TRANSPORTER (Aquifexaeolicus) |
PF00209(SNF) | 5 | ALA A 504LEU A 367VAL A 95LEU A 98LEU A 371 | BOG A 1 ( 4.2A)NoneNoneNoneNone | 1.08A | 1jipA-3mpnA:0.2 | 1jipA-3mpnA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n0r | RESPONSE REGULATOR (Caulobactervibrioides) |
PF00072(Response_reg) | 5 | ALA A 85GLY A 28THR A 27ALA A 35LEU A 79 | None | 1.18A | 1jipA-3n0rA:undetectable | 1jipA-3n0rA:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nfb | BETA-PEPTIDYLAMINOPEPTIDASE (Sphingosinicellaxenopeptidilytica) |
PF03576(Peptidase_S58) | 5 | ALA A 259GLY A 327ALA A 270THR A 320LEU A 261 | None | 1.30A | 1jipA-3nfbA:undetectable | 1jipA-3nfbA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ng3 | DEOXYRIBOSE-PHOSPHATE ALDOLASE (Mycobacteriumavium) |
PF01791(DeoC) | 5 | ALA A 207LEU A 200ALA A 197THR A 159LEU A 210 | NoneNone CL A 224 ( 3.8A)NoneNone | 1.35A | 1jipA-3ng3A:undetectable | 1jipA-3ng3A:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3opx | PROTEIN SSM1 (Saccharomycescerevisiae) |
PF13419(HAD_2) | 5 | GLY A 162LEU A 120LEU A 159THR A 140LEU A 41 | NoneNoneNoneU5P A 265 (-3.7A)None | 1.19A | 1jipA-3opxA:undetectable | 1jipA-3opxA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p56 | RIBONUCLEASE H2SUBUNIT A (Homo sapiens) |
PF01351(RNase_HII) | 5 | ALA A 48GLY A 37LEU A 16ALA A 189LEU A 93 | None | 1.42A | 1jipA-3p56A:undetectable | 1jipA-3p56A:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r4z | GLYCOSYL HYDROLASEFAMILY 32, NTERMINAL (Saccharophagusdegradans) |
PF04616(Glyco_hydro_43) | 5 | PHE A 313ALA A 55VAL A 140LEU A 139LEU A 57 | None | 0.92A | 1jipA-3r4zA:undetectable | 1jipA-3r4zA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sc3 | PUTATIVE DNAREPLICATIONREGULATOR HDA (Shewanellaamazonensis) |
PF00308(Bac_DnaA) | 5 | ALA A 124LEU A 101ARG A 131LEU A 140LEU A 98 | None | 1.32A | 1jipA-3sc3A:undetectable | 1jipA-3sc3A:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3swg | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Aquifexaeolicus) |
PF00275(EPSP_synthase) | 5 | PHE A 316ALA A 318THR A 244LEU A 347LEU A 344 | None | 1.17A | 1jipA-3swgA:undetectable | 1jipA-3swgA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ty4 | PROBABLEHOMOISOCITRATEDEHYDROGENASE (Schizosaccharomycespombe) |
PF00180(Iso_dh) | 5 | ALA A 322TYR A 326LEU A 28ALA A 25LEU A 313 | None | 1.38A | 1jipA-3ty4A:undetectable | 1jipA-3ty4A:23.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u44 | ATP-DEPENDENTHELICASE/NUCLEASESUBUNIT A (Bacillussubtilis) |
PF00580(UvrD-helicase)PF12705(PDDEXK_1)PF13361(UvrD_C) | 5 | GLY A 829LEU A 332LEU A 216THR A 832LEU A 335 | None | 1.36A | 1jipA-3u44A:undetectable | 1jipA-3u44A:15.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vrb | FLAVOPROTEIN SUBUNITOF COMPLEX II (Ascaris suum) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 5 | ALA A 258GLY A 238LEU A 204ALA A 418LEU A 259 | None | 1.42A | 1jipA-3vrbA:undetectable | 1jipA-3vrbA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zok | 3-DEHYDROQUINATESYNTHASE (Actinidiachinensis) |
PF01761(DHQ_synthase) | 5 | ALA A 289LEU A 204LEU A 311THR A 262LEU A 259 | PO4 A1380 (-3.2A)NoneNonePO4 A1380 (-3.4A)PO4 A1380 (-4.5A) | 1.39A | 1jipA-3zokA:undetectable | 1jipA-3zokA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zqj | UVRABC SYSTEMPROTEIN A (Mycobacteriumtuberculosis) |
PF00005(ABC_tran) | 5 | THR A 650LEU A 692LEU A 668ALA A 669LEU A 695 | None | 1.37A | 1jipA-3zqjA:undetectable | 1jipA-3zqjA:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ecg | PUTATIVEIRON-REGULATEDPROTEIN A (Parabacteroidesdistasonis) |
PF09375(Peptidase_M75) | 5 | ALA A 241GLY A 220VAL A 120LEU A 123ALA A 124 | None | 1.19A | 1jipA-4ecgA:undetectable | 1jipA-4ecgA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ecm | GLUCOSE-1-PHOSPHATETHYMIDYLYLTRANSFERASE (Bacillusanthracis) |
PF00483(NTP_transferase) | 5 | ALA A 129TYR A 174GLY A 170LEU A 203LEU A 208 | NoneNoneDAU A 301 ( 4.4A)NoneNone | 1.17A | 1jipA-4ecmA:undetectable | 1jipA-4ecmA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4frt | PROBABLE PORIN (Pseudomonasaeruginosa) |
PF03573(OprD) | 5 | GLY A 283THR A 284LEU A 60VAL A 153THR A 123 | None | 1.32A | 1jipA-4frtA:undetectable | 1jipA-4frtA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g4p | AMINO ACID ABCTRANSPORTER, AMINOACID-BINDING/PERMEASE PROTEIN (Enterococcusfaecalis) |
PF00497(SBP_bac_3) | 5 | ALA A 135GLY A 110LEU A 113THR A 139LEU A 145 | NoneNoneNoneGLN A 302 (-4.3A)None | 1.17A | 1jipA-4g4pA:undetectable | 1jipA-4g4pA:17.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gaa | MGC78867 PROTEIN (Xenopus laevis) |
PF01433(Peptidase_M1)PF09127(Leuk-A4-hydro_C) | 5 | GLY A 266ARG A 534VAL A 279LEU A 286ALA A 287 | BES A 702 (-4.3A)NoneNoneNoneNone | 0.94A | 1jipA-4gaaA:undetectable | 1jipA-4gaaA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gvf | BETA-HEXOSAMINIDASE (Salmonellaenterica) |
PF00933(Glyco_hydro_3) | 5 | ALA A 265GLY A 272LEU A 25ALA A 297LEU A 292 | None | 1.22A | 1jipA-4gvfA:undetectable | 1jipA-4gvfA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4izg | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME,N-TERMINAL DOMAINPROTEIN (Paracoccusdenitrificans) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | PHE A 279ALA A 277LEU A 123ALA A 108LEU A 124 | None | 1.35A | 1jipA-4izgA:undetectable | 1jipA-4izgA:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jlw | GLUTATHIONE-INDEPENDENT FORMALDEHYDEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | LEU A 348VAL A 363ALA A 201THR A 71LEU A 168 | None | 1.24A | 1jipA-4jlwA:undetectable | 1jipA-4jlwA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k28 | SHIKIMATEDEHYDROGENASE FAMILYPROTEIN (Pseudomonasputida) |
PF00899(ThiF)PF08501(Shikimate_dh_N) | 5 | GLY A 132LEU A 215LEU A 233THR A 153LEU A 185 | NAD A 301 (-3.4A)NoneNoneNoneNone | 1.42A | 1jipA-4k28A:undetectable | 1jipA-4k28A:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k5r | OXYGENASE (Streptomycesargillaceus) |
PF01494(FAD_binding_3) | 5 | ALA A 38GLY A 20LEU A 319ALA A 290LEU A 31 | NoneFAD A 601 ( 4.8A)NoneNoneNone | 1.24A | 1jipA-4k5rA:undetectable | 1jipA-4k5rA:24.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k70 | UL37 (Suidalphaherpesvirus1) |
PF03970(Herpes_UL37_1) | 5 | ALA A 61LEU A 68LEU A 103ALA A 102THR A 56 | None | 1.45A | 1jipA-4k70A:undetectable | 1jipA-4k70A:25.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4keg | MALTOSE-BINDINGPERIPLASMIC/PALATELUNG AND NASALEPITHELIUM CLONEFUSION PROTEIN (Escherichiacoli;Homo sapiens) |
PF01273(LBP_BPI_CETP)PF13416(SBP_bac_8) | 5 | ALA A1054GLY A1046THR A1045LEU A1231LEU A1234 | None | 0.85A | 1jipA-4kegA:undetectable | 1jipA-4kegA:24.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l22 | PHOSPHORYLASE (Streptococcusmutans) |
PF00343(Phosphorylase) | 5 | ALA A 738LEU A 450LEU A 428ALA A 429LEU A 447 | None | 0.89A | 1jipA-4l22A:undetectable | 1jipA-4l22A:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nek | ENOYL-COAHYDRATASE/CARNITHINERACEMASE (Magnetospirillummagneticum) |
PF00378(ECH_1) | 5 | PHE A 83ALA A 80TYR A 32GLY A 104LEU A 75 | None | 0.99A | 1jipA-4nekA:undetectable | 1jipA-4nekA:23.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nml | RIBULOSE 5-PHOSPHATEISOMERASE (Toxoplasmagondii) |
PF06026(Rib_5-P_isom_A) | 5 | GLY A 139THR A 138LEU A 236THR A 212LEU A 216 | None | 0.86A | 1jipA-4nmlA:undetectable | 1jipA-4nmlA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oan | TRAP DICARBOXYLATETRANSPORTER DCTPSUBUNIT (Rhodopseudomonaspalustris) |
PF03480(DctP) | 5 | GLY A 138LEU A 84VAL A 147LEU A 248LEU A 105 | None | 1.25A | 1jipA-4oanA:undetectable | 1jipA-4oanA:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oj5 | TAILSPIKE PROTEIN (Escherichiavirus CBA120) |
no annotation | 5 | ALA A 76VAL A 47LEU A 59THR A 53LEU A 72 | None | 1.21A | 1jipA-4oj5A:undetectable | 1jipA-4oj5A:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p72 | PHENYLALANINE--TRNALIGASE BETA SUBUNIT (Pseudomonasaeruginosa) |
PF01588(tRNA_bind)PF03147(FDX-ACB)PF03483(B3_4)PF03484(B5) | 5 | ALA A 180GLY A 29LEU A 429ALA A 466LEU A 432 | None | 1.37A | 1jipA-4p72A:undetectable | 1jipA-4p72A:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p72 | PHENYLALANINE--TRNALIGASE BETA SUBUNIT (Pseudomonasaeruginosa) |
PF01588(tRNA_bind)PF03147(FDX-ACB)PF03483(B3_4)PF03484(B5) | 5 | ALA A 640GLY A 527LEU A 670ALA A 519LEU A 666 | None | 1.09A | 1jipA-4p72A:undetectable | 1jipA-4p72A:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pvv | ADENOSINE KINASE (Mycobacteriumtuberculosis) |
PF00294(PfkB) | 5 | ALA A 303VAL A 59LEU A 60ALA A 56LEU A 282 | None | 1.16A | 1jipA-4pvvA:undetectable | 1jipA-4pvvA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pxb | UREIDOGLYCOLATEHYDROLASE (Arabidopsisthaliana) |
PF01546(Peptidase_M20) | 5 | ALA A 224TYR A 89GLY A 194THR A 181ALA A 205 | None | 1.42A | 1jipA-4pxbA:undetectable | 1jipA-4pxbA:23.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rk6 | GLUCOSE-RESISTANCEAMYLASE REGULATOR (Weissellaparamesenteroides) |
PF13377(Peripla_BP_3) | 5 | GLY A 251VAL A 182LEU A 181ALA A 180THR A 288 | None | 1.31A | 1jipA-4rk6A:undetectable | 1jipA-4rk6A:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rxl | MOLYBDENUM ABCTRANSPORTER,PERIPLASMICMOLYBDENUM-BINDINGPROTEIN (Vibrio cholerae) |
PF13531(SBP_bac_11) | 5 | ALA A 30TYR A 57LEU A 101VAL A 42LEU A 41 | None | 1.05A | 1jipA-4rxlA:undetectable | 1jipA-4rxlA:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v2p | KETOSYNTHASE (Myxococcusfulvus) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | ALA A 301GLY A 321THR A 320VAL A 270LEU A 271 | None | 1.07A | 1jipA-4v2pA:undetectable | 1jipA-4v2pA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xnu | INTEGRAL MEMBRANEPROTEIN-DOPAMINETRANSPORTER (Drosophilamelanogaster) |
PF00209(SNF) | 5 | PHE A 53ALA A 359LEU A 279LEU A 414LEU A 276 | CL A 603 ( 4.8A)NoneNoneNoneCLR A 604 ( 4.7A) | 1.44A | 1jipA-4xnuA:0.3 | 1jipA-4xnuA:23.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z61 | PHYTOSULFOKINERECEPTOR 1 (Daucus carota) |
PF00560(LRR_1)PF13855(LRR_8) | 5 | GLY A 43LEU A 112LEU A 37ALA A 36LEU A 115 | None | 1.29A | 1jipA-4z61A:undetectable | 1jipA-4z61A:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zdk | CTP SYNTHASE (Mycobacteriumtuberculosis) |
PF00117(GATase)PF06418(CTP_synth_N) | 5 | ALA A 380GLY A 344VAL A 307ALA A 305THR A 348 | None | 1.19A | 1jipA-4zdkA:undetectable | 1jipA-4zdkA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a60 | INORGANICTRIPHOSPHATASE (Escherichiacoli) |
PF01928(CYTH) | 5 | ALA A 294THR A 306VAL A 254ALA A 250THR A 299 | None | 0.95A | 1jipA-5a60A:undetectable | 1jipA-5a60A:24.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5avo | HOMOSERINEDEHYDROGENASE (Sulfurisphaeratokodaii) |
PF00742(Homoserine_dh)PF03447(NAD_binding_3) | 5 | PHE A 125GLY A 132LEU A 5ALA A 14THR A 128 | None | 1.17A | 1jipA-5avoA:undetectable | 1jipA-5avoA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cm9 | RAL GUANINENUCLEOTIDEDISSOCIATIONSTIMULATOR-LIKE 2 (Mus musculus) |
PF00617(RasGEF)PF00618(RasGEF_N) | 5 | ALA A 234LEU A 492VAL A 241THR A 309LEU A 495 | None | 1.29A | 1jipA-5cm9A:undetectable | 1jipA-5cm9A:24.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fms | INTRAFLAGELLARTRANSPORT PROTEIN 52HOMOLOG (Mus musculus) |
PF09822(ABC_transp_aux) | 5 | LEU A 84VAL A 183LEU A 198ALA A 199LEU A 241 | None | 1.24A | 1jipA-5fmsA:undetectable | 1jipA-5fmsA:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g10 | HDAH (Pseudomonasaeruginosa) |
PF00850(Hist_deacetyl) | 5 | ALA A 162THR A 188LEU A 127VAL A 198LEU A 123 | None | 1.20A | 1jipA-5g10A:undetectable | 1jipA-5g10A:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gte | LACHRYMATORY-FACTORSYNTHASE (Allium cepa) |
PF10604(Polyketide_cyc2) | 5 | PHE A 135ALA A 116TYR A 114LEU A 90VAL A 73 | None | 1.15A | 1jipA-5gteA:undetectable | 1jipA-5gteA:17.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hqw | PUTATIVE POLYKETIDESYNTHASE (Brevibacillusbrevis) |
PF14765(PS-DH) | 5 | GLY A2428LEU A2350VAL A2461LEU A2460ALA A2459 | None | 0.94A | 1jipA-5hqwA:undetectable | 1jipA-5hqwA:24.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hw3 | BETA-LACTAMASE (Burkholderiavietnamiensis) |
PF13354(Beta-lactamase2) | 5 | GLY A 55LEU A 193ARG A 249ALA A 186LEU A 194 | None | 1.27A | 1jipA-5hw3A:undetectable | 1jipA-5hw3A:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ixp | EXTRACELLULARSOLUTE-BINDINGPROTEIN FAMILY 1 (Kribbellaflavida) |
PF13416(SBP_bac_8) | 5 | TYR A 57GLY A 153THR A 154LEU A 47LEU A 333 | None | 0.89A | 1jipA-5ixpA:undetectable | 1jipA-5ixpA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jjq | AMP-DEPENDENTSYNTHETASE ANDLIGASE (Streptomycessp. ML694-90F3) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 5 | ALA A 84GLY A 92LEU A 118ALA A 117LEU A 73 | None | 1.18A | 1jipA-5jjqA:undetectable | 1jipA-5jjqA:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ks8 | PYRUVATE CARBOXYLASESUBUNIT BETA (Methylobacillusflagellatus) |
PF00364(Biotin_lipoyl)PF00682(HMGL-like)PF02436(PYC_OADA) | 5 | GLY C 228THR C 242LEU C 78VAL C 10LEU C 11 | None | 1.34A | 1jipA-5ks8C:undetectable | 1jipA-5ks8C:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lj9 | MACROLIDE EXPORTATP-BINDING/PERMEASEPROTEIN MACB (Escherichiacoli) |
no annotation | 5 | GLY A 148LEU A 190LEU A 132THR A 172LEU A 187 | None | 1.39A | 1jipA-5lj9A:undetectable | 1jipA-5lj9A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5my5 | ABC TRANSPORTERPERIPLASMICSUBSTRATE-BINDINGPROTEIN (Desulfovibrioalaskensis) |
PF12849(PBP_like_2) | 5 | ALA A 219GLY A 73THR A 74LEU A 34LEU A 5 | None | 1.27A | 1jipA-5my5A:undetectable | 1jipA-5my5A:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5no5 | ABYA5 (Verrucosispora) |
no annotation | 5 | ALA A 223GLY A 149THR A 148LEU A 284LEU A 224 | None | 1.39A | 1jipA-5no5A:undetectable | 1jipA-5no5A:12.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nr4 | CLIP-ASSOCIATINGPROTEIN 2 (Homo sapiens) |
no annotation | 5 | ALA A 191THR A 155LEU A 176ALA A 134LEU A 173 | None | 1.37A | 1jipA-5nr4A:undetectable | 1jipA-5nr4A:13.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5td3 | CATECHOL1,2-DIOXYGENASE (Burkholderiavietnamiensis) |
PF00775(Dioxygenase_C)PF04444(Dioxygenase_N) | 5 | GLY A 90LEU A 120LEU A 84ALA A 83THR A 115 | NoneNoneEDO A 403 ( 4.6A)NoneNone | 1.35A | 1jipA-5td3A:undetectable | 1jipA-5td3A:24.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uak | CYSTIC FIBROSISTRANSMEMBRANECONDUCTANCEREGULATOR (Homo sapiens) |
PF00005(ABC_tran)PF00664(ABC_membrane)PF14396(CFTR_R) | 5 | PHE A 305ALA A 309GLY A 241LEU A 230LEU A 233 | None | 1.34A | 1jipA-5uakA:0.0 | 1jipA-5uakA:14.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v76 | MICROCOMPARTMENTSPROTEIN (Haliangiumochraceum) |
no annotation | 5 | GLY A 87VAL A 8LEU A 9ALA A 34THR A 50 | None | 0.96A | 1jipA-5v76A:undetectable | 1jipA-5v76A:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vtm | TYPE II SECRETIONSYSTEM PROTEIN K (Pseudomonasaeruginosa) |
no annotation | 5 | ALA X 244LEU X 260VAL X 224LEU X 227ALA X 228 | None | 0.83A | 1jipA-5vtmX:undetectable | 1jipA-5vtmX:12.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vyl | INNER TEGUMENTPROTEIN (Humanalphaherpesvirus1) |
PF03970(Herpes_UL37_1) | 5 | GLY A 99LEU A 87LEU A 106ALA A 107LEU A 33 | None | 1.31A | 1jipA-5vylA:undetectable | 1jipA-5vylA:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wb5 | PUTATIVE EUKARYOTICTRANSLATIONINITIATION FACTOREIF-4E (Leishmaniamajor) |
no annotation | 5 | ALA A 192VAL A 96LEU A 173ALA A 174LEU A 145 | None | 1.19A | 1jipA-5wb5A:undetectable | 1jipA-5wb5A:11.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fik | POLYKETIDE SYNTHASE (Cercosporanicotianae) |
no annotation | 5 | ALA A 563GLY A 504VAL A 740LEU A 743LEU A 625 | None | 1.32A | 1jipA-6fikA:undetectable | 1jipA-6fikA:12.73 |