SIMILAR PATTERNS OF AMINO ACIDS FOR 1JIN_A_KTNA801

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c2o ACETYLCHOLINESTERASE

(Electrophorus
electricus) 		PF00135
(COesterase) 		6 PHE A 200
ALA A 225
VAL A 411
LEU A 414
ALA A 415
ALA A 419
 None
 1.14A 1jinA-1c2oA:
0.0		 1jinA-1c2oA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c7g TYROSINE
PHENOL-LYASE

(Pantoea
agglomerans) 		PF01212
(Beta_elim_lyase) 		5 THR A  35
VAL A 403
LEU A 347
ALA A 349
LEU A 427
 None
 1.05A 1jinA-1c7gA:
0.0		 1jinA-1c7gA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cmv HUMAN
CYTOMEGALOVIRUS
PROTEASE

(Human
betaherpesvirus
5) 		PF00716
(Peptidase_S21) 		5 ALA A 171
TYR A 173
VAL A  69
LEU A  59
LEU A 131
 None
 1.08A 1jinA-1cmvA:
0.0		 1jinA-1cmvA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gnw GLUTATHIONE
S-TRANSFERASE

(Arabidopsis
thaliana) 		PF00043
(GST_C)
PF02798
(GST_N) 		5 ALA A 175
VAL A 146
LEU A 147
ALA A 144
LEU A 179
 None
 1.02A 1jinA-1gnwA:
1.9		 1jinA-1gnwA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iug PUTATIVE ASPARTATE
AMINOTRANSFERASE

(Thermus
thermophilus) 		PF00266
(Aminotran_5) 		5 ALA A 202
THR A  49
VAL A  53
ALA A  63
LEU A  71
 None
 1.01A 1jinA-1iugA:
undetectable		 1jinA-1iugA:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iug PUTATIVE ASPARTATE
AMINOTRANSFERASE

(Thermus
thermophilus) 		PF00266
(Aminotran_5) 		5 ALA A 202
THR A  49
VAL A  53
LEU A  54
ALA A  63
 None
 0.80A 1jinA-1iugA:
undetectable		 1jinA-1iugA:
25.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1jio CYTOCHROME P450
107A1

(Saccharopolyspora
erythraea) 		PF00067
(p450) 		5 PHE A  72
ALA A  74
ALA A 245
THR A 292
LEU A 391
 None
DEB  A 420 (-3.8A)
HEM  A 410 (-3.5A)
None
DEB  A 420 ( 4.8A)
 1.02A 1jinA-1jioA:
68.3		 1jinA-1jioA:
98.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1jio CYTOCHROME P450
107A1

(Saccharopolyspora
erythraea) 		PF00067
(p450) 		6 PHE A  72
ALA A  74
TYR A  75
LEU A 240
THR A 292
LEU A 391
 None
DEB  A 420 (-3.8A)
DEB  A 420 ( 4.8A)
DEB  A 420 ( 4.5A)
None
DEB  A 420 ( 4.8A)
 0.93A 1jinA-1jioA:
68.3		 1jinA-1jioA:
98.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1jio CYTOCHROME P450
107A1

(Saccharopolyspora
erythraea) 		PF00067
(p450) 		10 SER A  59
ALA A  74
TYR A  75
THR A  92
VAL A 237
LEU A 240
ALA A 241
ALA A 245
THR A 292
LEU A 391
 HEM  A 410 ( 4.9A)
DEB  A 420 (-3.8A)
DEB  A 420 ( 4.8A)
DEB  A 420 (-4.2A)
DEB  A 420 ( 4.3A)
DEB  A 420 ( 4.5A)
DEB  A 420 ( 3.6A)
HEM  A 410 (-3.5A)
None
DEB  A 420 ( 4.8A)
 0.69A 1jinA-1jioA:
68.3		 1jinA-1jioA:
98.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k6y INTEGRASE

(Human
immunodeficiency
virus 1) 		PF00665
(rve)
PF02022
(Integrase_Zn) 		6 ALA A  76
THR A 115
VAL A 126
ALA A 129
ALA A 133
LEU A 104
 None
 1.47A 1jinA-1k6yA:
0.0		 1jinA-1k6yA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1koe ENDOSTATIN

(Mus musculus) 		PF06482
(Endostatin) 		5 SER A 285
ALA A 229
VAL A 239
ALA A 145
LEU A 210
 None
 0.87A 1jinA-1koeA:
0.0		 1jinA-1koeA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ktw IOTA-CARRAGEENASE

(Alteromonas sp.
ATCC 43554) 		PF12708
(Pectate_lyase_3) 		5 PHE A 263
ALA A 264
VAL A 383
ALA A 301
ALA A 274
 None
 1.07A 1jinA-1ktwA:
0.0		 1jinA-1ktwA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1odt CEPHALOSPORIN C
DEACETYLASE

(Bacillus
subtilis) 		PF05448
(AXE1) 		5 SER C 264
PHE C 278
ALA C 280
ALA C 191
ALA C 190
 None
 1.06A 1jinA-1odtC:
undetectable		 1jinA-1odtC:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pby QUINOHEMOPROTEIN
AMINE DEHYDROGENASE
60 KDA SUBUNIT

(Paracoccus
denitrificans) 		PF09098
(Dehyd-heme_bind)
PF09099
(Qn_am_d_aIII)
PF09100
(Qn_am_d_aIV)
PF14930
(Qn_am_d_aII) 		5 PHE A 244
THR A 232
ALA A  57
ALA A  58
LEU A 224
 None
 1.07A 1jinA-1pbyA:
undetectable		 1jinA-1pbyA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t1e KUMAMOLISIN

(Bacillus sp.
MN-32) 		PF00082
(Peptidase_S8)
PF09286
(Pro-kuma_activ) 		5 PHE A 172
ALA A 468
LEU A 278
ALA A 279
ALA A 478
 None
 1.06A 1jinA-1t1eA:
undetectable		 1jinA-1t1eA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tez DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE

(Synechococcus
elongatus) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		5 ALA A  69
LEU A  21
ALA A  22
ALA A  26
LEU A 171
 None
 1.07A 1jinA-1tezA:
undetectable		 1jinA-1tezA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w4t ARYLAMINE
N-ACETYLTRANSFERASE

(Pseudomonas
aeruginosa) 		PF00797
(Acetyltransf_2) 		5 VAL A 266
LEU A 269
ALA A 270
ALA A 274
LEU A 210
 None
 1.06A 1jinA-1w4tA:
undetectable		 1jinA-1w4tA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wk4 TTK003001606

(Thermus
thermophilus) 		PF00583
(Acetyltransf_1) 		5 ALA A  75
VAL A  17
LEU A  18
ALA A  15
ALA A  44
 None
 1.08A 1jinA-1wk4A:
undetectable		 1jinA-1wk4A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wyd HYPOTHETICAL
ASPARTYL-TRNA
SYNTHETASE

(Sulfurisphaera
tokodaii) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		5 SER A  67
ALA A  22
VAL A  48
LEU A  87
ALA A  89
 None
 1.08A 1jinA-1wydA:
undetectable		 1jinA-1wydA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xco PHOSPHATE
ACETYLTRANSFERASE

(Bacillus
subtilis) 		PF01515
(PTA_PTB) 		5 VAL A 311
LEU A 314
ALA A 315
ALA A 319
LEU A 121
 None
 0.96A 1jinA-1xcoA:
undetectable		 1jinA-1xcoA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d1f THREONINE SYNTHASE

(Mycobacterium
tuberculosis) 		PF00291
(PALP) 		6 ALA A  44
THR A  51
LEU A 286
ALA A 283
ALA A 300
LEU A  57
 None
 1.44A 1jinA-2d1fA:
undetectable		 1jinA-2d1fA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE

(Porphyromonas
gingivalis) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		5 ALA A 625
LEU A 666
ALA A 663
ALA A 692
LEU A 672
 None
 1.04A 1jinA-2d5lA:
undetectable		 1jinA-2d5lA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eih ALCOHOL
DEHYDROGENASE

(Thermus
thermophilus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		5 ALA A 254
ALA A 198
ALA A 175
THR A 231
LEU A 171
 None
 1.03A 1jinA-2eihA:
undetectable		 1jinA-2eihA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fjk FRUCTOSE-BISPHOSPHAT
E ALDOLASE

(Thermus
caldophilus) 		PF01116
(F_bP_aldolase) 		5 ALA A  32
THR A  24
VAL A  64
LEU A  67
ALA A  68
 None
 1.02A 1jinA-2fjkA:
undetectable		 1jinA-2fjkA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii) 		PF00440
(TetR_N)
PF13977
(TetR_C_6) 		5 ALA A  53
VAL A  26
ALA A  30
ALA A  33
LEU A   9
 None
 1.06A 1jinA-2g3bA:
2.0		 1jinA-2g3bA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Staphylococcus
aureus) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		5 ALA A 351
ALA A  82
ALA A  83
THR A 169
LEU A 239
 None
 0.98A 1jinA-2gqdA:
undetectable		 1jinA-2gqdA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL

(Rattus
norvegicus) 		PF00755
(Carn_acyltransf) 		5 ALA A 650
VAL A 466
LEU A 469
ALA A 470
ALA A 474
 None
 1.02A 1jinA-2h4tA:
undetectable		 1jinA-2h4tA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h84 STEELY1

(Dictyostelium
discoideum) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		5 PHE A2979
THR A2899
VAL A2868
LEU A2871
ALA A2872
 None
 0.88A 1jinA-2h84A:
undetectable		 1jinA-2h84A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mjl PEPTIDYL-TRNA
HYDROLASE

(Vibrio cholerae) 		PF01195
(Pept_tRNA_hydro) 		5 ALA A  77
LEU A  12
ALA A  13
ALA A  28
LEU A  65
 None
 1.01A 1jinA-2mjlA:
undetectable		 1jinA-2mjlA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p9b POSSIBLE PROLIDASE

(Bifidobacterium
longum) 		PF01979
(Amidohydro_1) 		5 ALA A 190
VAL A 243
ALA A 245
ALA A 206
LEU A 179
 None
 0.99A 1jinA-2p9bA:
undetectable		 1jinA-2p9bA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pcq PUTATIVE
DIHYDRODIPICOLINATE
SYNTHASE

(Thermus
thermophilus) 		PF00701
(DHDPS) 		5 ALA A  94
VAL A 139
LEU A 142
ALA A 143
LEU A 121
 None
 0.99A 1jinA-2pcqA:
undetectable		 1jinA-2pcqA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pyu INOSINE TRIPHOSPHATE
PYROPHOSPHATASE RDGB

(Escherichia
coli) 		PF01725
(Ham1p_like) 		5 ALA A  65
VAL A  14
LEU A  17
ALA A  18
THR A  61
 None
 1.06A 1jinA-2pyuA:
undetectable		 1jinA-2pyuA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q5o PHENYLPYRUVATE
DECARBOXYLASE

(Azospirillum
brasilense) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		5 PHE A 301
ALA A 300
VAL A 222
LEU A 225
ALA A 226
 None
 0.95A 1jinA-2q5oA:
undetectable		 1jinA-2q5oA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r4j AEROBIC
GLYCEROL-3-PHOSPHATE
DEHYDROGENASE

(Escherichia
coli) 		PF01266
(DAO)
PF16901
(DAO_C) 		5 ALA A 449
LEU A 413
ALA A 414
ALA A 418
LEU A 428
 None
 1.03A 1jinA-2r4jA:
undetectable		 1jinA-2r4jA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x75 ADENYLOSUCCINATE
LYASE

(Staphylococcus
aureus) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		5 ALA A  22
THR A  15
VAL A  56
ALA A  59
ALA A  72
 None
 0.91A 1jinA-2x75A:
0.6		 1jinA-2x75A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus) 		PF00142
(Fer4_NifH) 		5 VAL A 147
LEU A  30
ALA A 168
THR A  45
LEU A 172
 None
 1.08A 1jinA-2ynmA:
undetectable		 1jinA-2ynmA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a5r BENZALACETONE
SYNTHASE

(Rheum palmatum) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		5 VAL A 163
LEU A 166
ALA A 167
ALA A 171
THR A 138
 None
 0.91A 1jinA-3a5rA:
undetectable		 1jinA-3a5rA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bf0 PROTEASE 4

(Escherichia
coli) 		PF01343
(Peptidase_S49) 		5 ALA A 333
VAL A 384
ALA A 387
ALA A 390
LEU A 370
 None
 1.03A 1jinA-3bf0A:
undetectable		 1jinA-3bf0A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bfg CLASS A
BETA-LACTAMASE SED1

(Citrobacter
sedlakii) 		PF13354
(Beta-lactamase2) 		5 ALA A 237
VAL A 278
LEU A 279
ALA A 280
ALA A 223
 MER  A 301 (-4.2A)
None
None
None
None
 1.08A 1jinA-3bfgA:
undetectable		 1jinA-3bfgA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3do6 FORMATE--TETRAHYDROF
OLATE LIGASE

(Thermotoga
maritima) 		PF01268
(FTHFS) 		5 ALA A 124
THR A 154
ALA A 192
ALA A 195
LEU A 236
 None
 1.06A 1jinA-3do6A:
undetectable		 1jinA-3do6A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ez1 AMINOTRANSFERASE
MOCR FAMILY

(Deinococcus
geothermalis) 		PF12897
(Aminotran_MocR) 		5 ALA A  13
VAL A 359
LEU A 362
ALA A 363
ALA A 366
 None
 1.08A 1jinA-3ez1A:
undetectable		 1jinA-3ez1A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fvr ACETYL XYLAN
ESTERASE

(Bacillus
pumilus) 		PF05448
(AXE1) 		5 PHE A 278
ALA A 280
ALA A 191
ALA A 190
LEU A 250
 None
 1.05A 1jinA-3fvrA:
undetectable		 1jinA-3fvrA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gbw E3 UBIQUITIN-PROTEIN
LIGASE MYCBP2

(Mus musculus) 		PF08005
(PHR) 		5 SER A1250
VAL A1304
LEU A1305
ALA A1306
LEU A1269
 None
 1.07A 1jinA-3gbwA:
undetectable		 1jinA-3gbwA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gx8 MONOTHIOL
GLUTAREDOXIN-5,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF00462
(Glutaredoxin) 		5 ALA A 124
VAL A  75
LEU A 139
ALA A 138
ALA A 136
 None
 1.02A 1jinA-3gx8A:
undetectable		 1jinA-3gx8A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hvd PROTECTIVE ANTIGEN

(Bacillus
anthracis) 		PF03495
(Binary_toxB)
PF17475
(Binary_toxB_2)
PF17476
(Binary_toxB_3) 		5 ALA A 604
THR A 702
VAL A 612
ALA A 615
LEU A 498
 None
 0.99A 1jinA-3hvdA:
undetectable		 1jinA-3hvdA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i7j BETA-LACTAMASE
MB2281C

(Mycobacterium
bovis) 		PF00144
(Beta-lactamase) 		5 SER A  70
VAL A  59
ALA A  53
ALA A  49
LEU A 202
 None
 1.06A 1jinA-3i7jA:
undetectable		 1jinA-3i7jA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k21 CALCIUM-DEPENDENT
PROTEIN KINASE 3

(Plasmodium
falciparum) 		PF13499
(EF-hand_7) 		5 TYR A 149
LEU A  37
ALA A  38
ALA A 127
THR A 141
 None
 1.06A 1jinA-3k21A:
undetectable		 1jinA-3k21A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k70 EXODEOXYRIBONUCLEASE
V ALPHA CHAIN

(Escherichia
coli) 		PF13538
(UvrD_C_2)
PF13604
(AAA_30) 		5 ALA D 373
VAL D 566
ALA D 589
ALA D 588
THR D 384
 None
 1.02A 1jinA-3k70D:
undetectable		 1jinA-3k70D:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kl9 GLUTAMYL
AMINOPEPTIDASE

(Streptococcus
pneumoniae) 		PF05343
(Peptidase_M42) 		5 THR A 254
LEU A 233
ALA A 234
ALA A 295
LEU A 265
 None
 0.97A 1jinA-3kl9A:
0.8		 1jinA-3kl9A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lki FRUCTOKINASE

(Xylella
fastidiosa) 		PF00294
(PfkB) 		5 SER A 145
LEU A 216
ALA A 213
ALA A 220
LEU A 227
 None
 1.04A 1jinA-3lkiA:
undetectable		 1jinA-3lkiA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m5w TRYPTOPHANYL-TRNA
SYNTHETASE

(Campylobacter
jejuni) 		PF00579
(tRNA-synt_1b) 		6 PHE A  76
VAL A  85
LEU A 134
ALA A 130
ALA A 129
LEU A   4
 None
 1.25A 1jinA-3m5wA:
undetectable		 1jinA-3m5wA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mkb HEMOGLOBIN SUBUNIT
ALPHA

(Isurus
oxyrinchus) 		PF00042
(Globin) 		5 SER A 117
LEU A  17
ALA A  14
ALA A  70
LEU A 128
 None
 1.03A 1jinA-3mkbA:
1.7		 1jinA-3mkbA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nu1 HEMIN-BINDING
PERIPLASMIC PROTEIN

(Yersinia pestis) 		PF01497
(Peripla_BP_2) 		5 ALA A 187
THR A 116
LEU A 257
ALA A 256
LEU A 268
 None
 0.98A 1jinA-3nu1A:
undetectable		 1jinA-3nu1A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ogz UDP-SUGAR
PYROPHOSPHORYLASE

(Leishmania
major) 		PF01704
(UDPGP) 		5 SER A 358
ALA A 276
VAL A 120
LEU A 119
THR A 297
 None
 1.00A 1jinA-3ogzA:
undetectable		 1jinA-3ogzA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pkj NAD-DEPENDENT
DEACETYLASE
SIRTUIN-6

(Homo sapiens) 		PF02146
(SIR2) 		5 ALA A  95
VAL A  32
LEU A  35
ALA A  36
LEU A  99
 None
 1.04A 1jinA-3pkjA:
undetectable		 1jinA-3pkjA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans) 		PF04616
(Glyco_hydro_43) 		5 PHE A 313
ALA A  55
VAL A 140
LEU A 139
LEU A  57
 None
 0.97A 1jinA-3r4zA:
undetectable		 1jinA-3r4zA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3smv S-(-)-AZETIDINE-2-CA
RBOXYLATE HYDROLASE

(Pseudomonas sp.
AC2) 		PF13419
(HAD_2) 		5 SER A 196
PHE A   6
ALA A   8
THR A 178
LEU A 165
 None
 1.03A 1jinA-3smvA:
undetectable		 1jinA-3smvA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tfo PUTATIVE
3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE

(Sinorhizobium
meliloti) 		PF00106
(adh_short) 		5 ALA A  74
LEU A  60
ALA A  35
ALA A  12
LEU A  32
 None
 0.96A 1jinA-3tfoA:
undetectable		 1jinA-3tfoA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v2i PEPTIDYL-TRNA
HYDROLASE

(Burkholderia
thailandensis) 		PF01195
(Pept_tRNA_hydro) 		5 SER A  73
VAL A  27
LEU A  30
ALA A  31
ALA A  36
 None
 1.04A 1jinA-3v2iA:
undetectable		 1jinA-3v2iA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wdb PROBABLE
ATP-DEPENDENT CLP
PROTEASE ATP-BINDING
SUBUNIT

(Mycobacterium
tuberculosis) 		PF02861
(Clp_N) 		5 SER A  48
VAL A  12
LEU A  15
ALA A  16
LEU A  56
 None
 1.01A 1jinA-3wdbA:
undetectable		 1jinA-3wdbA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zhb R-IMINE REDUCTASE

(Streptomyces
kanamyceticus) 		PF03446
(NAD_binding_2) 		6 SER A  76
ALA A  35
ALA A  52
ALA A  53
THR A  45
LEU A  58
 None
 1.38A 1jinA-3zhbA:
undetectable		 1jinA-3zhbA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zqj UVRABC SYSTEM
PROTEIN A

(Mycobacterium
tuberculosis) 		PF00005
(ABC_tran) 		5 VAL A 664
LEU A 668
ALA A 669
ALA A 673
LEU A 695
 None
 1.05A 1jinA-3zqjA:
undetectable		 1jinA-3zqjA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d4z DEOXYHYPUSINE
HYDROXYLASE

(Homo sapiens) 		PF13646
(HEAT_2) 		5 ALA A 276
VAL A 222
LEU A 225
ALA A 226
ALA A 230
 None
 1.06A 1jinA-4d4zA:
undetectable		 1jinA-4d4zA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ef1 PHEROMONE
COB1/LIPOPROTEIN,
YAEC FAMILY

(Enterococcus
faecalis) 		PF03180
(Lipoprotein_9) 		5 PHE A 205
ALA A 206
LEU A 220
ALA A 219
THR A 188
 None
 0.85A 1jinA-4ef1A:
undetectable		 1jinA-4ef1A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eff AROMATIC-AMINO-ACID
AMINOTRANSFERASE

(Burkholderia
pseudomallei) 		PF00155
(Aminotran_1_2) 		5 VAL A 299
LEU A 300
ALA A 301
ALA A  75
THR A 290
 None
 0.89A 1jinA-4effA:
undetectable		 1jinA-4effA:
24.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ep6 CYTOCHROME P450-LIKE
PROTEIN XPLA

(Rhodococcus
rhodochrous) 		PF00067
(p450) 		5 PHE A 388
ALA A 390
ALA A 337
ALA A 338
LEU A 344
 HEM  A 601 (-4.2A)
None
None
None
None
 0.97A 1jinA-4ep6A:
43.9		 1jinA-4ep6A:
30.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fix UDP-GALACTOFURANOSYL
TRANSFERASE GLFT2

(Mycobacterium
tuberculosis) 		PF13641
(Glyco_tranf_2_3) 		5 ALA A 178
THR A 168
LEU A 222
ALA A 194
LEU A 182
 None
 1.05A 1jinA-4fixA:
undetectable		 1jinA-4fixA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fqd NIKO PROTEIN

(Streptomyces
tendae) 		PF00275
(EPSP_synthase) 		5 TYR A 438
VAL A 414
ALA A 418
ALA A 421
LEU A 445
 None
 1.06A 1jinA-4fqdA:
undetectable		 1jinA-4fqdA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g25 PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL

(Arabidopsis
thaliana) 		PF16953
(PRORP)
PF17177
(PPR_long) 		5 PHE A 414
THR A 419
ALA A 464
ALA A 462
LEU A 455
 None
 1.06A 1jinA-4g25A:
undetectable		 1jinA-4g25A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g25 PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL

(Arabidopsis
thaliana) 		PF16953
(PRORP)
PF17177
(PPR_long) 		6 PHE A 414
VAL A 435
LEU A 465
ALA A 464
ALA A 462
LEU A 455
 None
 1.22A 1jinA-4g25A:
undetectable		 1jinA-4g25A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g2t SSFS6

(Streptomyces
sp. SF2575) 		PF00201
(UDPGT)
PF06722
(DUF1205) 		5 ALA A 126
VAL A 150
LEU A 153
ALA A 154
LEU A 160
 None
 0.91A 1jinA-4g2tA:
undetectable		 1jinA-4g2tA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hea NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 14

(Thermus
thermophilus) 		PF00361
(Proton_antipo_M) 		6 PHE N 349
ALA N 272
LEU N 223
ALA N 219
ALA N 218
LEU N 281
 None
 1.36A 1jinA-4heaN:
undetectable		 1jinA-4heaN:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hgv FUMARATE HYDRATASE
CLASS II

(Sinorhizobium
meliloti) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		5 ALA A 290
VAL A 383
LEU A 386
ALA A 387
ALA A 173
 None
 1.09A 1jinA-4hgvA:
0.0		 1jinA-4hgvA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j5q O-ACETYL-ADP-RIBOSE
DEACETYLASE 1

(Homo sapiens) 		PF01661
(Macro) 		5 SER A  65
ALA A  69
THR A  83
ALA A  45
LEU A  58
 None
 1.05A 1jinA-4j5qA:
undetectable		 1jinA-4j5qA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l22 PHOSPHORYLASE

(Streptococcus
mutans) 		PF00343
(Phosphorylase) 		5 SER A 743
ALA A 738
LEU A 428
ALA A 429
LEU A 447
 None
 1.06A 1jinA-4l22A:
undetectable		 1jinA-4l22A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n18 D-ISOMER SPECIFIC
2-HYDROXYACID
DEHYDROGENASE FAMILY
PROTEIN

(Klebsiella
pneumoniae) 		PF02826
(2-Hacid_dh_C) 		5 ALA A 246
LEU A 206
ALA A 207
ALA A 208
LEU A 243
 None
 1.04A 1jinA-4n18A:
undetectable		 1jinA-4n18A:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pqo SORTING NEXIN-14

(Homo sapiens) 		PF00787
(PX) 		6 SER A 625
TYR A 663
LEU A 683
ALA A 680
THR A 628
LEU A 673
 None
 1.30A 1jinA-4pqoA:
undetectable		 1jinA-4pqoA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pvv ADENOSINE KINASE

(Mycobacterium
tuberculosis) 		PF00294
(PfkB) 		6 ALA A 303
VAL A  59
LEU A  60
ALA A  56
ALA A 258
LEU A 282
 None
 1.21A 1jinA-4pvvA:
undetectable		 1jinA-4pvvA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q05 ESTERASE E25

(uncultured
bacterium) 		PF07859
(Abhydrolase_3) 		5 SER A 146
ALA A 181
THR A 116
ALA A 327
LEU A 335
 None
 1.04A 1jinA-4q05A:
undetectable		 1jinA-4q05A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rh7 GREEN FLUORESCENT
PROTEIN/CYTOPLASMIC
DYNEIN 2 HEAVY CHAIN
1

(Homo sapiens;
synthetic
construct) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		5 THR A4105
VAL A4111
LEU A4114
ALA A4115
LEU A4044
 None
 0.98A 1jinA-4rh7A:
undetectable		 1jinA-4rh7A:
7.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wum CHALCONE SYNTHASE

(Freesia hybrid
cultivar) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		5 VAL A 170
LEU A 173
ALA A 174
ALA A 178
THR A 145
 None
 0.88A 1jinA-4wumA:
undetectable		 1jinA-4wumA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xg0 UNCHARACTERIZED
PROTEIN

(Bordetella
bronchiseptica) 		PF07005
(DUF1537)
PF17042
(DUF1357_C) 		5 ALA A 321
VAL A 237
ALA A 295
ALA A 260
LEU A 298
 None
 1.06A 1jinA-4xg0A:
undetectable		 1jinA-4xg0A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xll DJ-1 FAMILY PROTEIN

(Toxoplasma
gondii) 		PF01965
(DJ-1_PfpI) 		5 SER A 151
ALA A  69
VAL A 167
LEU A 168
ALA A  28
 None
 0.88A 1jinA-4xllA:
undetectable		 1jinA-4xllA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a60 INORGANIC
TRIPHOSPHATASE

(Escherichia
coli) 		PF01928
(CYTH) 		5 ALA A 294
THR A 306
VAL A 254
ALA A 250
THR A 299
 None
 0.94A 1jinA-5a60A:
undetectable		 1jinA-5a60A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5da8 60 KDA CHAPERONIN

(Chlorobaculum
tepidum) 		PF00118
(Cpn60_TCP1) 		6 PHE A   8
ALA A  12
VAL A 107
LEU A 104
ALA A 512
LEU A  16
 None
 1.39A 1jinA-5da8A:
undetectable		 1jinA-5da8A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ez3 ACYL-COA
DEHYDROGENASE

(Brucella
melitensis) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M) 		5 ALA A 323
TYR A 549
LEU A 401
ALA A 398
ALA A 427
 None
 0.99A 1jinA-5ez3A:
1.1		 1jinA-5ez3A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f9s SERINE--PYRUVATE
AMINOTRANSFERASE

(Homo sapiens) 		PF00266
(Aminotran_5) 		6 PHE A 310
LEU A 384
ALA A 383
ALA A 379
THR A 323
LEU A 302
 None
 1.26A 1jinA-5f9sA:
undetectable		 1jinA-5f9sA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g10 HDAH

(Pseudomonas
aeruginosa) 		PF00850
(Hist_deacetyl) 		5 PHE A 368
ALA A 253
VAL A 293
ALA A 297
ALA A 301
 None
 1.08A 1jinA-5g10A:
undetectable		 1jinA-5g10A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzg F-BOX/LRR-REPEAT
MAX2 HOMOLOG

(Oryza sativa) 		no annotation 5 ALA B 264
VAL B 217
LEU B 220
ALA B 254
LEU B 262
 None
 1.07A 1jinA-5hzgB:
undetectable		 1jinA-5hzgB:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i2h O-METHYLTRANSFERASE
FAMILY 2

(Planctopirus
limnophila) 		PF00891
(Methyltransf_2)
PF16864
(Dimerisation2) 		5 VAL A 176
LEU A 177
ALA A 174
ALA A 210
LEU A 264
 None
 1.08A 1jinA-5i2hA:
undetectable		 1jinA-5i2hA:
25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5inw PUTATIVE
ANGIOTENSINOGEN

(Lampetra
fluviatilis) 		PF00079
(Serpin) 		5 SER A 364
ALA A 134
VAL A 119
ALA A 115
LEU A  87
 None
 1.03A 1jinA-5inwA:
undetectable		 1jinA-5inwA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5inw PUTATIVE
ANGIOTENSINOGEN

(Lampetra
fluviatilis) 		PF00079
(Serpin) 		5 SER A 369
ALA A 134
VAL A 119
ALA A 115
LEU A  87
 None
 1.08A 1jinA-5inwA:
undetectable		 1jinA-5inwA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j78 ACETALDEHYDE
DEHYDROGENASE
(ACETYLATING)

(Parageobacillus
thermoglucosidasius) 		PF00171
(Aldedh) 		5 PHE A 267
LEU A 279
ALA A 369
ALA A 348
LEU A 345
 None
 1.05A 1jinA-5j78A:
undetectable		 1jinA-5j78A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jbk BETA-GLUCOSIDASE

(Trichoderma
harzianum) 		PF00232
(Glyco_hydro_1) 		5 SER A 300
THR A 229
ALA A 252
ALA A 255
LEU A 168
 None
 1.09A 1jinA-5jbkA:
undetectable		 1jinA-5jbkA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lsr CCMP

(Synechococcus
elongatus) 		no annotation 5 ALA A 194
VAL A 169
ALA A 171
ALA A 149
LEU A 198
 None
 1.06A 1jinA-5lsrA:
undetectable		 1jinA-5lsrA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ngk GLUCOSYLCERAMIDASE

(Bacteroides
thetaiotaomicron) 		PF02055
(Glyco_hydro_30)
PF17189
(Glyco_hydro_30C) 		5 PHE A 279
ALA A 278
LEU A 263
ALA A 262
LEU A 308
 None
 1.07A 1jinA-5ngkA:
undetectable		 1jinA-5ngkA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE

(Persicaria
tinctoria) 		no annotation 5 PHE A  72
VAL A 120
LEU A 119
ALA A 118
ALA A 117
 None
 0.99A 1jinA-5nlmA:
undetectable		 1jinA-5nlmA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uc5 CHS2 CHALCONE
SYNTHASE

(Malus domestica) 		no annotation 5 VAL A 170
LEU A 173
ALA A 174
ALA A 178
THR A 145
 None
 0.96A 1jinA-5uc5A:
undetectable		 1jinA-5uc5A:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE

(environmental
samples) 		PF00202
(Aminotran_3) 		5 ALA A 320
LEU A 108
ALA A 109
ALA A 115
THR A 280
 None
 1.04A 1jinA-5uc7A:
undetectable		 1jinA-5uc7A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vop 5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE

(Thermus
thermophilus) 		no annotation 5 ALA A 449
VAL A 478
LEU A 481
ALA A 482
ALA A 487
 None
 0.91A 1jinA-5vopA:
undetectable		 1jinA-5vopA:
13.90