SIMILAR PATTERNS OF AMINO ACIDS FOR 1JHA_A_NIOA991
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1chk | CHITOSANASE (Streptomycessp. N174) |
PF01374(Glyco_hydro_46) | 4 | GLY A 139GLY A 185PHE A 186LEU A 187 | None | 0.60A | 1jhaA-1chkA:undetectable | 1jhaA-1chkA:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dr6 | DIHYDROFOLATEREDUCTASE (Gallus gallus) |
PF00186(DHFR_1) | 4 | GLY A 117GLY A 15PHE A 148GLY A 17 | NAP A 191 (-3.3A)MBO A 201 ( 4.2A)NoneNAP A 191 (-3.6A) | 0.74A | 1jhaA-1dr6A:undetectable | 1jhaA-1dr6A:19.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j0a | 1-AMINOCYCLOPROPANE-1-CARBOXYLATEDEAMINASE (Pyrococcushorikoshii) |
PF00291(PALP) | 4 | GLY A 213LEU A 227SER A 199GLY A 193 | NoneNoneNonePLP A 401 (-3.6A) | 0.75A | 1jhaA-1j0aA:2.4 | 1jhaA-1j0aA:24.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1j33 | COBT (Thermusthermophilus) |
PF02277(DBI_PRT) | 6 | THR A 168GLY A 190GLY A 251PHE A 252SER A 278ARG A 279 | None | 0.97A | 1jhaA-1j33A:42.4 | 1jhaA-1j33A:36.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1j33 | COBT (Thermusthermophilus) |
PF02277(DBI_PRT) | 6 | THR A 168GLY A 190GLY A 251PHE A 252SER A 278GLY A 303 | None | 0.46A | 1jhaA-1j33A:42.4 | 1jhaA-1j33A:36.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jft | PURINE NUCLEOTIDESYNTHESIS REPRESSOR (Escherichiacoli) |
PF00356(LacI)PF13377(Peripla_BP_3) | 4 | GLY A 246GLY A 199PHE A 200GLY A 195 | None | 0.56A | 1jhaA-1jftA:undetectable | 1jhaA-1jftA:23.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jhz | PURINE NUCLEOTIDESYNTHESIS REPRESSOR (Escherichiacoli) |
PF13377(Peripla_BP_3) | 4 | GLY A 246GLY A 199PHE A 200GLY A 195 | None | 0.67A | 1jhaA-1jhzA:undetectable | 1jhaA-1jhzA:24.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kkm | HPRK PROTEIN (Lactobacilluscasei) |
PF07475(Hpr_kinase_C) | 4 | GLY A 172GLY A 218PHE A 217ARG A 174 | None | 0.75A | 1jhaA-1kkmA:undetectable | 1jhaA-1kkmA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kpl | PUTATIVE CLC FAMILY,CHLORINE TRANSPORTPROTEIN (Salmonellaenterica) |
PF00654(Voltage_CLC) | 4 | THR A 138GLY A 134GLY A 355GLY A 106 | NoneNone CL A 503 (-3.5A)None | 0.73A | 1jhaA-1kplA:undetectable | 1jhaA-1kplA:24.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m54 | CYSTATHIONINEBETA-SYNTHASE (Homo sapiens) |
PF00291(PALP) | 4 | GLY A 279GLY A 259LEU A 315GLY A 256 | NonePLP A1110 (-3.6A)NonePLP A1110 (-3.2A) | 0.75A | 1jhaA-1m54A:undetectable | 1jhaA-1m54A:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1olp | ALPHA-TOXIN (Clostridiumsardiniense) |
PF00882(Zn_dep_PLPC)PF01477(PLAT) | 4 | THR A 16GLY A 51PHE A 48GLY A 7 | None | 0.78A | 1jhaA-1olpA:undetectable | 1jhaA-1olpA:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pyf | IOLS PROTEIN (Bacillussubtilis) |
PF00248(Aldo_ket_red) | 4 | GLY A 19GLY A 24SER A 63GLY A 37 | None | 0.72A | 1jhaA-1pyfA:undetectable | 1jhaA-1pyfA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rf5 | 5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATESYNTHASE (Streptococcuspneumoniae) |
PF00275(EPSP_synthase) | 4 | GLY A 100GLY A 133LEU A 155GLY A 151 | None | 0.66A | 1jhaA-1rf5A:undetectable | 1jhaA-1rf5A:25.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) |
PF01593(Amino_oxidase) | 4 | THR A 246GLY A 49GLY A 241ARG A 53 | None | 0.51A | 1jhaA-1sezA:undetectable | 1jhaA-1sezA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1thg | LIPASE 2 (Galactomycescandidus) |
PF00135(COesterase) | 4 | GLY A 215GLY A 464LEU A 467GLY A 131 | None | 0.75A | 1jhaA-1thgA:2.0 | 1jhaA-1thgA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u70 | DIHYDROFOLATEREDUCTASE (Mus musculus) |
PF00186(DHFR_1) | 4 | GLY A 117GLY A 15PHE A 148GLY A 17 | NDP A 188 (-2.3A)NoneNoneNDP A 188 ( 3.9A) | 0.72A | 1jhaA-1u70A:undetectable | 1jhaA-1u70A:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v10 | LACCASE (Rigidoporusmicroporus) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 4 | GLY A 277GLY A 179LEU A 190GLY A 188 | None | 0.76A | 1jhaA-1v10A:undetectable | 1jhaA-1v10A:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bmo | OXYGENASE-ALPHA NBDO (Comamonas sp.JS765) |
PF00355(Rieske)PF00848(Ring_hydroxyl_A) | 4 | THR A 241GLY A 413GLY A 296GLY A 202 | None | 0.61A | 1jhaA-2bmoA:undetectable | 1jhaA-2bmoA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e1t | ACYL TRANSFERASE (Chrysanthemum xmorifolium) |
PF02458(Transferase) | 4 | GLY A 449GLY A 338PHE A 339SER A 285 | None | 0.72A | 1jhaA-2e1tA:undetectable | 1jhaA-2e1tA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eid | GALACTOSE OXIDASE (Fusariumgraminearum) |
PF00754(F5_F8_type_C)PF01344(Kelch_1)PF09118(DUF1929) | 4 | GLY A 394GLY A 339PHE A 338GLY A 611 | None | 0.75A | 1jhaA-2eidA:undetectable | 1jhaA-2eidA:19.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2m48 | E3 UBIQUITIN-PROTEINLIGASE PARKIN (Drosophilamelanogaster) |
PF01485(IBR) | 4 | THR A 372GLY A 378GLY A 388PHE A 381 | None | 0.75A | 1jhaA-2m48A:undetectable | 1jhaA-2m48A:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pqd | 3-PHOSPHOSHIKIMATE1-CARBOXYVINYLTRANSFERASE (Agrobacteriumsp.) |
PF00275(EPSP_synthase) | 4 | THR A 59GLY A 38PHE A 35ARG A 33 | NoneNoneNoneGG9 A 501 (-2.8A) | 0.70A | 1jhaA-2pqdA:undetectable | 1jhaA-2pqdA:24.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qc3 | MALONYL COA-ACYLCARRIER PROTEINTRANSACYLASE (Mycobacteriumtuberculosis) |
PF00698(Acyl_transf_1) | 4 | GLY A 93GLY A 272LEU A 274SER A 11 | None | 0.66A | 1jhaA-2qc3A:undetectable | 1jhaA-2qc3A:27.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qfr | PURPLE ACIDPHOSPHATASE (Phaseolusvulgaris) |
PF00149(Metallophos)PF14008(Metallophos_C)PF16656(Pur_ac_phosph_N) | 4 | THR A 129GLY A 156PHE A 130GLY A 390 | None | 0.70A | 1jhaA-2qfrA:undetectable | 1jhaA-2qfrA:18.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qk4 | TRIFUNCTIONAL PURINEBIOSYNTHETIC PROTEINADENOSINE-3 (Homo sapiens) |
PF01071(GARS_A)PF02843(GARS_C)PF02844(GARS_N) | 4 | GLY A 351GLY A 384SER A 341GLY A 371 | NoneGOL A 804 (-3.6A)NoneNone | 0.57A | 1jhaA-2qk4A:undetectable | 1jhaA-2qk4A:24.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qsd | UNCHARACTERIZEDCONSERVED PROTEIN (Idiomarinaloihiensis) |
PF07566(DUF1543) | 4 | GLY A 19GLY A 15LEU A 24GLY A 48 | None | 0.64A | 1jhaA-2qsdA:undetectable | 1jhaA-2qsdA:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xd4 | PHOSPHORIBOSYLAMINE--GLYCINE LIGASE (Bacillussubtilis) |
PF01071(GARS_A)PF02843(GARS_C)PF02844(GARS_N) | 4 | GLY A 343GLY A 375SER A 333GLY A 362 | None | 0.77A | 1jhaA-2xd4A:undetectable | 1jhaA-2xd4A:24.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y27 | PHENYLACETATE-COENZYME A LIGASE (Burkholderiacenocepacia) |
PF00501(AMP-binding)PF14535(AMP-binding_C_2) | 4 | THR A 184GLY A 421GLY A 144GLY A 162 | None | 0.63A | 1jhaA-2y27A:undetectable | 1jhaA-2y27A:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yw2 | PHOSPHORIBOSYLAMINE--GLYCINE LIGASE (Aquifexaeolicus) |
PF01071(GARS_A)PF02843(GARS_C)PF02844(GARS_N) | 4 | GLY A 343GLY A 377SER A 333GLY A 364 | None | 0.71A | 1jhaA-2yw2A:undetectable | 1jhaA-2yw2A:23.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a9l | POLY-GAMMA-GLUTAMATEHYDROLASE (Bacillus virusNIT1) |
PF05908(Gamma_PGA_hydro) | 4 | GLY A 161LEU A 118ARG A 155GLY A 159 | None | 0.67A | 1jhaA-3a9lA:undetectable | 1jhaA-3a9lA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c4n | UNCHARACTERIZEDPROTEIN DR_0571 (Deinococcusradiodurans) |
PF01266(DAO) | 4 | THR A 79GLY A 45GLY A 383GLY A 375 | ADP A 411 (-3.6A)ADP A 411 (-3.5A)NoneADP A 411 ( 4.4A) | 0.74A | 1jhaA-3c4nA:undetectable | 1jhaA-3c4nA:24.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dfh | MANDELATE RACEMASE (VibrionalesbacteriumSWAT-3) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | GLY A 368GLY A 38PHE A 37GLY A 318 | None | 0.67A | 1jhaA-3dfhA:undetectable | 1jhaA-3dfhA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g77 | CYTOSINE DEAMINASE (Escherichiacoli) |
PF07969(Amidohydro_3) | 4 | THR A 200GLY A 181GLY A 165GLY A 158 | None | 0.77A | 1jhaA-3g77A:2.6 | 1jhaA-3g77A:25.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h5j | 3-ISOPROPYLMALATEDEHYDRATASE SMALLSUBUNIT (Mycobacteriumtuberculosis) |
PF00694(Aconitase_C) | 4 | GLY A 98GLY A 68PHE A 71SER A 94 | None | 0.66A | 1jhaA-3h5jA:undetectable | 1jhaA-3h5jA:17.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hdg | UNCHARACTERIZEDPROTEIN (Wolinellasuccinogenes) |
PF00072(Response_reg) | 4 | THR A 58GLY A 67GLY A 39GLY A 44 | None | 0.77A | 1jhaA-3hdgA:3.0 | 1jhaA-3hdgA:14.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hfq | UNCHARACTERIZEDPROTEIN LP_2219 (Lactobacillusplantarum) |
PF10282(Lactonase) | 4 | GLY A 34GLY A 8PHE A 7GLY A 17 | None | 0.70A | 1jhaA-3hfqA:undetectable | 1jhaA-3hfqA:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hrd | NICOTINATEDEHYDROGENASEFAD-SUBUNITNICOTINATEDEHYDROGENASE SMALLFES SUBUNIT (Eubacteriumbarkeri) |
PF00111(Fer2)PF00941(FAD_binding_5)PF01799(Fer2_2)PF03450(CO_deh_flav_C) | 4 | THR D 60GLY D 45GLY C 109GLY C 33 | FES D 908 (-4.2A)FES D 908 ( 3.2A)FAD C 900 ( 3.8A)FAD C 900 (-3.3A) | 0.65A | 1jhaA-3hrdD:undetectable | 1jhaA-3hrdD:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ih6 | PUTATIVE ZINCPROTEASE (Bordetellapertussis) |
PF05193(Peptidase_M16_C) | 4 | GLY A 342PHE A 341LEU A 313ARG A 440 | None | 0.64A | 1jhaA-3ih6A:undetectable | 1jhaA-3ih6A:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3il7 | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 3 (Staphylococcusaureus) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 4 | GLY A 301PHE A 298SER A 113GLY A 181 | None | 0.68A | 1jhaA-3il7A:undetectable | 1jhaA-3il7A:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n7t | MACROPHAGE BINDINGPROTEIN (Coccidioidesimmitis) |
PF01965(DJ-1_PfpI) | 4 | THR A 233GLY A 138GLY A 103GLY A 135 | None | 0.71A | 1jhaA-3n7tA:3.4 | 1jhaA-3n7tA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o75 | FRUCTOSE TRANSPORTSYSTEM REPRESSORFRUR (Pseudomonasputida) |
PF00532(Peripla_BP_1) | 4 | GLY A 186GLY A 200PHE A 201SER A 167 | None | 0.67A | 1jhaA-3o75A:undetectable | 1jhaA-3o75A:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pqs | TRANSFERRIN-BINDINGPROTEIN (Actinobacilluspleuropneumoniae) |
PF01298(TbpB_B_D)PF17483(TbpB_C)PF17484(TbpB_A) | 4 | GLY A 438GLY A 521LEU A 503GLY A 505 | NoneNoneNoneGOL A 529 ( 4.3A) | 0.75A | 1jhaA-3pqsA:undetectable | 1jhaA-3pqsA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tav | METHIONINEAMINOPEPTIDASE (Mycobacteroidesabscessus) |
PF00557(Peptidase_M24) | 4 | GLY A 176PHE A 175LEU A 220ARG A 165 | None | 0.68A | 1jhaA-3tavA:undetectable | 1jhaA-3tavA:25.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tt2 | GCN5-RELATEDN-ACETYLTRANSFERASE (Sphaerobacterthermophilus) |
PF00583(Acetyltransf_1) | 5 | THR A 234GLY A 250GLY A 237LEU A 236GLY A 247 | None | 1.29A | 1jhaA-3tt2A:undetectable | 1jhaA-3tt2A:23.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uma | HYPOTHETICALPEROXIREDOXINPROTEIN (Sinorhizobiummeliloti) |
PF08534(Redoxin) | 4 | THR A 48GLY A 147GLY A 153SER A 152 | None | 0.76A | 1jhaA-3umaA:undetectable | 1jhaA-3umaA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ure | ALPHA-LYTIC PROTEASE (Lysobacterenzymogenes) |
PF00089(Trypsin) | 4 | THR A 143GLY A 191GLY A 19SER A 43 | None | 0.76A | 1jhaA-3ureA:undetectable | 1jhaA-3ureA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vbe | BETA-CYANOALNINESYNTHASE (Glycine max) |
PF00291(PALP) | 4 | GLY A 253GLY A 233LEU A 284GLY A 230 | NonePLP A 500 (-3.8A)NonePLP A 500 (-3.2A) | 0.74A | 1jhaA-3vbeA:undetectable | 1jhaA-3vbeA:24.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wc3 | ENDO-1,4-BETA-GLUCANASE (Eisenia fetida) |
PF00759(Glyco_hydro_9) | 4 | GLY A 168GLY A 82PHE A 83GLY A 135 | None | 0.78A | 1jhaA-3wc3A:undetectable | 1jhaA-3wc3A:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4af0 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Cryptococcusneoformans) |
PF00478(IMPDH)PF00571(CBS) | 4 | GLY B 358GLY B 340ARG B 355GLY B 338 | NoneMOA B1526 (-4.0A)NoneNone | 0.77A | 1jhaA-4af0B:undetectable | 1jhaA-4af0B:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ako | SPORE COAT PROTEIN A (Bacillussubtilis) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 4 | GLY A 237GLY A 50LEU A 48GLY A 167 | NoneNoneCSX A 35 ( 4.4A)None | 0.72A | 1jhaA-4akoA:undetectable | 1jhaA-4akoA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cvc | ALCOHOLDEHYDROGENASE (Pseudogluconobactersaccharoketogenes) |
PF13360(PQQ_2) | 4 | THR A 121GLY A 103SER A 556GLY A 598 | None | 0.68A | 1jhaA-4cvcA:undetectable | 1jhaA-4cvcA:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fys | AMINOPEPTIDASE N (Homo sapiens) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 4 | THR A 928GLY A 933PHE A 930GLY A 893 | None | 0.76A | 1jhaA-4fysA:undetectable | 1jhaA-4fysA:16.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g9i | HYDROGENASEMATURATION PROTEINHYPF (Thermococcuskodakarensis) |
PF00708(Acylphosphatase)PF00814(Peptidase_M22)PF01300(Sua5_yciO_yrdC)PF07503(zf-HYPF) | 4 | THR A 605GLY A 602GLY A 559SER A 562 | None | 0.75A | 1jhaA-4g9iA:2.1 | 1jhaA-4g9iA:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gi2 | CROTONYL-COACARBOXYLASE/REDUCTASE (Methylobacteriumextorquens) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLY A 80GLY A 46SER A 51GLY A 86 | None | 0.77A | 1jhaA-4gi2A:3.2 | 1jhaA-4gi2A:25.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jn6 | 4-HYDROXY-2-OXOVALERATE ALDOLASE (Mycobacteriumtuberculosis) |
PF00682(HMGL-like)PF07836(DmpG_comm) | 4 | GLY A 199GLY A 231SER A 290GLY A 229 | None | 0.67A | 1jhaA-4jn6A:2.9 | 1jhaA-4jn6A:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k29 | ENOYL-COAHYDRATASE/ISOMERASE (Xanthobacterautotrophicus) |
PF00378(ECH_1) | 4 | GLY A 140LEU A 137SER A 242GLY A 142 | None | 0.78A | 1jhaA-4k29A:undetectable | 1jhaA-4k29A:24.53 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4kqk | NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLEPHOSPHORIBOSYLTRANSFERASE (Salmonellaenterica) |
PF02277(DBI_PRT) | 7 | THR A 180GLY A 202GLY A 264PHE A 265LEU A 266ARG A 314GLY A 316 | SO4 A 402 (-2.9A)SO4 A 402 (-3.6A)NoneNoneNoneNoneNone | 0.42A | 1jhaA-4kqkA:62.9 | 1jhaA-4kqkA:98.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4kqk | NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLEPHOSPHORIBOSYLTRANSFERASE (Salmonellaenterica) |
PF02277(DBI_PRT) | 7 | THR A 180GLY A 202GLY A 264PHE A 265SER A 291ARG A 314GLY A 316 | SO4 A 402 (-2.9A)SO4 A 402 (-3.6A)NoneNoneNoneNoneNone | 0.39A | 1jhaA-4kqkA:62.9 | 1jhaA-4kqkA:98.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lds | BICYCLOMYCINRESISTANCE PROTEINTCAB (Staphylococcusepidermidis) |
PF00083(Sugar_tr) | 4 | GLY A 284GLY A 28SER A 263GLY A 24 | None | 0.74A | 1jhaA-4ldsA:undetectable | 1jhaA-4ldsA:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mnr | PEPTIDOGLYCANGLYCOSYLTRANSFERASE (Eggerthellalenta) |
PF00905(Transpeptidase) | 4 | THR A 191GLY A 257GLY A 246GLY A 250 | None | 0.69A | 1jhaA-4mnrA:undetectable | 1jhaA-4mnrA:25.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n6d | TRAP DICARBOXYLATETRANSPORTER-DCTPSUBUNIT (Desulfovibriosalexigens) |
PF03480(DctP) | 4 | GLY A 86LEU A 74SER A 33GLY A 91 | NoneNone CL A 403 (-4.6A)None | 0.74A | 1jhaA-4n6dA:undetectable | 1jhaA-4n6dA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o4x | TBPB (Glaesserellaparasuis) |
PF01298(TbpB_B_D)PF17483(TbpB_C)PF17484(TbpB_A) | 4 | GLY A 445GLY A 530LEU A 510GLY A 512 | None | 0.78A | 1jhaA-4o4xA:undetectable | 1jhaA-4o4xA:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ope | NRPS/PKS (Streptomycesalbus) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 4 | GLY A4535GLY A4448PHE A4447GLY A4451 | None | 0.69A | 1jhaA-4opeA:undetectable | 1jhaA-4opeA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p8e | 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATESYNTHASE (Vibrio cholerae) |
PF00926(DHBP_synthase) | 5 | GLY A 171GLY A 27LEU A 24SER A 50GLY A 29 | None | 0.90A | 1jhaA-4p8eA:undetectable | 1jhaA-4p8eA:23.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wec | SHORT CHAINDEHYDROGENASE (Mycolicibacteriumsmegmatis) |
PF13561(adh_short_C2) | 4 | THR A 239GLY A 171GLY A 135GLY A 178 | None | 0.72A | 1jhaA-4wecA:4.1 | 1jhaA-4wecA:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x68 | BETA-LACTAMASE (Pseudomonasaeruginosa) |
PF00144(Beta-lactamase) | 4 | GLY A 297GLY A 183PHE A 185GLY A 248 | None | 0.70A | 1jhaA-4x68A:undetectable | 1jhaA-4x68A:23.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yjy | CHALCONE SYNTHASE 1 (Oryza sativa) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 4 | THR A 135GLY A 166LEU A 266GLY A 259 | None | 0.76A | 1jhaA-4yjyA:undetectable | 1jhaA-4yjyA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yw5 | NEURAMINIDASE C (Streptococcuspneumoniae) |
PF02012(BNR)PF02973(Sialidase)PF13088(BNR_2) | 4 | GLY A 127GLY A 234PHE A 243GLY A 96 | None | 0.77A | 1jhaA-4yw5A:undetectable | 1jhaA-4yw5A:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5az0 | UNCHARACTERIZEDPROTEIN (Bombyx mori) |
PF00248(Aldo_ket_red) | 4 | THR A 312GLY A 227GLY A 309PHE A 310 | NoneNoneNoneACT A 406 (-3.5A) | 0.64A | 1jhaA-5az0A:undetectable | 1jhaA-5az0A:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d0f | UNCHARACTERIZEDPROTEIN ([Candida]glabrata) |
PF06202(GDE_C)PF14699(hGDE_N)PF14701(hDGE_amylase)PF14702(hGDE_central) | 4 | THR A 123GLY A 15GLY A 63PHE A 113 | None | 0.74A | 1jhaA-5d0fA:undetectable | 1jhaA-5d0fA:12.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5erb | POLYKETIDE SYNTHASE (Bacillusamyloliquefaciens) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 4 | GLY A 325GLY A 238PHE A 237GLY A 241 | None | 0.76A | 1jhaA-5erbA:undetectable | 1jhaA-5erbA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5erb | POLYKETIDE SYNTHASE (Bacillusamyloliquefaciens) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 4 | THR A 320GLY A 325GLY A 238GLY A 241 | None | 0.70A | 1jhaA-5erbA:undetectable | 1jhaA-5erbA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f1u | 4-HYDROXY-TETRAHYDRODIPICOLINATESYNTHASE (Campylobacterjejuni) |
PF00701(DHDPS) | 4 | THR A 222GLY A 8GLY A 202LEU A 199 | None | 0.73A | 1jhaA-5f1uA:1.8 | 1jhaA-5f1uA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fsb | TECTONIN 2 (Laccariabicolor) |
no annotation | 4 | GLY A 16GLY A 127SER A 167GLY A 129 | None | 0.77A | 1jhaA-5fsbA:undetectable | 1jhaA-5fsbA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fsb | TECTONIN 2 (Laccariabicolor) |
no annotation | 4 | GLY A 91GLY A 205SER A 14GLY A 207 | None | 0.71A | 1jhaA-5fsbA:undetectable | 1jhaA-5fsbA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g0a | TRANSAMINASE (Bacillusmegaterium) |
PF00202(Aminotran_3) | 5 | THR A 273GLY A 283GLY A 385LEU A 387GLY A 383 | None | 1.14A | 1jhaA-5g0aA:undetectable | 1jhaA-5g0aA:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gjn | LYSINE/ORNITHINEDECARBOXYLASE (Selenomonasruminantium) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 4 | GLY A 319PHE A 318LEU A 285GLY A 288 | None | 0.73A | 1jhaA-5gjnA:undetectable | 1jhaA-5gjnA:23.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gnx | BETA-GLUCOSIDASE (metagenome) |
PF00232(Glyco_hydro_1) | 4 | GLY A 450GLY A 14PHE A 15ARG A 10 | None | 0.76A | 1jhaA-5gnxA:undetectable | 1jhaA-5gnxA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hxs | SODIUM,CALCIUMEXCHANGER (Methanocaldococcusjannaschii) |
PF01699(Na_Ca_ex) | 4 | GLY A 119GLY A 242LEU A 245GLY A 128 | SR A 402 ( 4.6A)NoneNoneNone | 0.76A | 1jhaA-5hxsA:undetectable | 1jhaA-5hxsA:23.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jjc | CYSTEINE SYNTHASE (Brucellaabortus) |
PF00291(PALP) | 4 | GLY A 185GLY A 237LEU A 214GLY A 235 | LLP A 42 ( 3.4A)NoneNoneNone | 0.75A | 1jhaA-5jjcA:undetectable | 1jhaA-5jjcA:23.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jnq | PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE ([Clostridium]bolteae) |
PF00953(Glycos_transf_4)PF10555(MraY_sig1) | 5 | GLY A 216PHE A 217LEU A 214SER A 16GLY A 212 | None | 1.07A | 1jhaA-5jnqA:undetectable | 1jhaA-5jnqA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k1s | OXIDOREDUCTASE,ZINC-BINDINGDEHYDROGENASE FAMILY (Myxococcusxanthus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | THR A 292GLY A 152LEU A 87GLY A 133 | None | 0.76A | 1jhaA-5k1sA:3.6 | 1jhaA-5k1sA:25.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m45 | ACETONE CARBOXYLASEBETA SUBUNIT (Xanthobacterautotrophicus) |
PF01968(Hydantoinase_A)PF05378(Hydant_A_N) | 4 | GLY B 285GLY B 311SER B 314GLY B 20 | NoneAMP B 801 (-3.5A)NoneAMP B 801 ( 3.7A) | 0.72A | 1jhaA-5m45B:undetectable | 1jhaA-5m45B:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n7q | PUTATIVE CATHEPSIN D (Ixodes ricinus) |
no annotation | 4 | GLY A 96GLY A 175PHE A 174GLY A 4 | None | 0.72A | 1jhaA-5n7qA:undetectable | 1jhaA-5n7qA:16.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nbs | BETA-GLUCOSIDASE (Neurosporacrassa) |
no annotation | 4 | GLY A 441GLY A 447LEU A 91GLY A 449 | None | 0.77A | 1jhaA-5nbsA:undetectable | 1jhaA-5nbsA:14.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nil | MACROLIDE EXPORTATP-BINDING/PERMEASEPROTEIN MACB (Escherichiacoli) |
PF00005(ABC_tran)PF02687(FtsX)PF12704(MacB_PCD) | 4 | THR J 389GLY J 374GLY J 381PHE J 377 | None | 0.78A | 1jhaA-5nilJ:undetectable | 1jhaA-5nilJ:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5szj | RAS-RELATED PROTEINRAB-10 (Homo sapiens) |
PF00071(Ras) | 4 | GLY A 121GLY A 94PHE A 97SER A 96 | None | 0.75A | 1jhaA-5szjA:undetectable | 1jhaA-5szjA:18.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t98 | GLYCOSIDE HYDROLASE (Bacteroidesuniformis) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF16355(DUF4982) | 4 | GLY A 109GLY A 190PHE A 107GLY A 192 | None | 0.72A | 1jhaA-5t98A:undetectable | 1jhaA-5t98A:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tzy | FREE FATTY ACIDRECEPTOR1,ENDOLYSIN,FREEFATTY ACID RECEPTOR1 (Escherichiavirus T4;Homo sapiens) |
PF00001(7tm_1)PF00959(Phage_lysozyme) | 4 | GLY A 94GLY A2265SER A2268GLY A2238 | None | 0.73A | 1jhaA-5tzyA:undetectable | 1jhaA-5tzyA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uc5 | CHS2 CHALCONESYNTHASE (Malus domestica) |
no annotation | 4 | THR A 132GLY A 163LEU A 263GLY A 256 | None | 0.75A | 1jhaA-5uc5A:undetectable | 1jhaA-5uc5A:13.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5utu | ADENOSYLHOMOCYSTEINASE (Cryptosporidiumparvum) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | THR A 212GLY A 138GLY A 332GLY A 355 | NAD A 501 ( 4.1A)SAH A 502 ( 3.9A)NAD A 501 (-3.5A)NAD A 501 (-3.4A) | 0.77A | 1jhaA-5utuA:2.4 | 1jhaA-5utuA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vip | MDCD (Pseudomonasaeruginosa) |
PF01039(Carboxyl_trans) | 4 | GLY B 185GLY B 162SER B 164GLY B 120 | None | 0.75A | 1jhaA-5vipB:2.5 | 1jhaA-5vipB:25.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xbp | 3NT OXYGENASE ALPHASUBUNIT (Diaphorobactersp. DS2) |
PF00355(Rieske)PF00848(Ring_hydroxyl_A) | 4 | THR A 241GLY A 413GLY A 296GLY A 202 | None | 0.61A | 1jhaA-5xbpA:undetectable | 1jhaA-5xbpA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xlu | GAMMA GLUTAMYLTRANSPEPTIDASE (Bacilluslicheniformis) |
no annotation | 4 | GLY A 86GLY A 149LEU A 150SER A 108 | GLY A 86 ( 0.0A)GLY A 149 ( 0.0A)LEU A 150 ( 0.6A)SER A 108 ( 0.0A) | 0.72A | 1jhaA-5xluA:undetectable | 1jhaA-5xluA:13.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xya | - (-) |
no annotation | 4 | THR A 407GLY A 352GLY A 380GLY A 348 | None | 0.65A | 1jhaA-5xyaA:undetectable | 1jhaA-5xyaA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z0u | NEOPULLULANASE 1 (Thermoactinomycesvulgaris) |
no annotation | 4 | GLY A 510PHE A 476SER A 469GLY A 513 | None | 0.69A | 1jhaA-5z0uA:undetectable | 1jhaA-5z0uA:10.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6b5f | NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLEPHOSPHORIBOSYLTRANSFERASE (Yersiniaenterocolitica) |
no annotation | 8 | THR A 179GLY A 201GLY A 263PHE A 264LEU A 265SER A 290ARG A 313GLY A 315 | SO4 A 401 (-2.8A)SO4 A 401 ( 3.7A)NoneNoneNoneNoneNoneNone | 0.39A | 1jhaA-6b5fA:59.5 | 1jhaA-6b5fA:67.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c6l | V-TYPE PROTON ATPASESUBUNIT A, VACUOLARISOFORM (Saccharomycescerevisiae) |
no annotation | 4 | GLY A 339GLY A 34LEU A 33GLY A 37 | None | 0.70A | 1jhaA-6c6lA:undetectable | 1jhaA-6c6lA:14.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d14 | TNFRECEPTOR-ASSOCIATEDPROTEIN 1 (Danio rerio) |
no annotation | 4 | GLY A 188GLY A 250LEU A 113SER A 248 | None | 0.77A | 1jhaA-6d14A:undetectable | 1jhaA-6d14A:11.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fay | ODZ3 PROTEIN (Mus musculus) |
no annotation | 4 | GLY A1759GLY A1727LEU A1728GLY A2013 | None | 0.71A | 1jhaA-6fayA:undetectable | 1jhaA-6fayA:13.37 |