SIMILAR PATTERNS OF AMINO ACIDS FOR 1JGS_A_SALA256

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ais PROTEIN
(TRANSCRIPTION
INITIATION FACTOR
IIB)

(Pyrococcus
woesei) 		PF00382
(TFIIB) 		4 LEU B1116
THR B1120
LEU B1123
VAL B1168
 None
 0.85A 1jgsA-1aisB:
0.0		 1jgsA-1aisB:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1icf PROTEIN (CATHEPSIN
L: HEAVY CHAIN)

(Homo sapiens) 		PF00112
(Peptidase_C1) 		4 LEU A  53
THR A  31
LEU A  34
VAL A 106
 None
 0.97A 1jgsA-1icfA:
0.0		 1jgsA-1icfA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jov HI1317

(Haemophilus
influenzae) 		PF01263
(Aldose_epim) 		4 VAL A  16
LEU A   5
THR A   8
LEU A   9
 None
 0.88A 1jgsA-1jovA:
0.0		 1jgsA-1jovA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kol FORMALDEHYDE
DEHYDROGENASE

(Pseudomonas
putida) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 VAL A  91
LEU A 148
LEU A 151
VAL A  41
 None
 0.73A 1jgsA-1kolA:
0.0		 1jgsA-1kolA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nkq HYPOTHETICAL 28.8
KDA PROTEIN IN
PSD1-SKO1 INTERGENIC
REGION

(Saccharomyces
cerevisiae) 		PF01557
(FAA_hydrolase) 		4 VAL A 116
LEU A  90
THR A 214
VAL A  94
 None
 0.96A 1jgsA-1nkqA:
0.0		 1jgsA-1nkqA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nz0 RIBONUCLEASE P
PROTEIN COMPONENT

(Thermotoga
maritima) 		PF00825
(Ribonuclease_P) 		4 VAL A  49
LEU A  13
LEU A  46
VAL A  34
 None
 0.87A 1jgsA-1nz0A:
undetectable		 1jgsA-1nz0A:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ope SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE

(Sus scrofa) 		PF01144
(CoA_trans) 		4 VAL A 400
LEU A 360
THR A 358
LEU A 357
 None
 0.69A 1jgsA-1opeA:
0.0		 1jgsA-1opeA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1or8 PROTEIN ARGININE
N-METHYLTRANSFERASE
1

(Rattus
norvegicus) 		PF13649
(Methyltransf_25) 		4 VAL A 182
LEU A 255
LEU A 227
VAL A 298
 None
 0.77A 1jgsA-1or8A:
0.3		 1jgsA-1or8A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgu PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)

(Klebsiella
pneumoniae) 		PF00148
(Oxidored_nitro) 		4 VAL A 434
THR A 464
LEU A 465
VAL A 349
 None
 0.92A 1jgsA-1qguA:
undetectable		 1jgsA-1qguA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t34 ATRIAL NATRIURETIC
PEPTIDE RECEPTOR A

(Rattus
norvegicus) 		PF01094
(ANF_receptor) 		4 PRO A 103
VAL A  80
LEU A 105
THR A 124
 None
 0.93A 1jgsA-1t34A:
undetectable		 1jgsA-1t34A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vc2 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Thermus
thermophilus) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 VAL A 157
THR A 213
LEU A 217
VAL A 167
 None
 0.93A 1jgsA-1vc2A:
undetectable		 1jgsA-1vc2A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6

(Saccharomyces
cerevisiae) 		PF00443
(UCH) 		4 PRO A 181
VAL A 182
THR A 117
LEU A 120
 None
 0.90A 1jgsA-1vjvA:
undetectable		 1jgsA-1vjvA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wk9 VALYL-TRNA
SYNTHETASE

(Thermus
thermophilus) 		PF00133
(tRNA-synt_1) 		4 VAL A 215
LEU A 197
THR A 199
LEU A 200
 TSB  A 999 (-3.8A)
None
None
None
 0.87A 1jgsA-1wk9A:
undetectable		 1jgsA-1wk9A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wyt GLYCINE
DEHYDROGENASE
(DECARBOXYLATING)
SUBUNIT 1

(Thermus
thermophilus) 		PF02347
(GDC-P) 		4 VAL A 153
LEU A 178
THR A 180
LEU A 181
 None
 0.93A 1jgsA-1wytA:
undetectable		 1jgsA-1wytA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xtt PROBABLE URACIL
PHOSPHORIBOSYLTRANSF
ERASE

(Sulfolobus
solfataricus) 		PF14681
(UPRTase) 		4 VAL A 167
LEU A  89
LEU A  32
VAL A 191
 None
 0.83A 1jgsA-1xttA:
undetectable		 1jgsA-1xttA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y9k IAA
ACETYLTRANSFERASE

(Bacillus cereus) 		PF00583
(Acetyltransf_1) 		4 VAL A  46
LEU A  17
LEU A  71
VAL A   3
 None
 0.80A 1jgsA-1y9kA:
undetectable		 1jgsA-1y9kA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yr1 CELL-DIVISION
INITIATION PROTEIN

(Geobacillus
stearothermophilus) 		no annotation 4 PRO A 153
VAL A 154
THR A 168
LEU A 171
 None
 0.90A 1jgsA-1yr1A:
undetectable		 1jgsA-1yr1A:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zyl HYPOTHETICAL PROTEIN
YIHE

(Escherichia
coli) 		PF01636
(APH) 		4 VAL A  53
LEU A  34
THR A  32
LEU A  31
 None
 0.78A 1jgsA-1zylA:
undetectable		 1jgsA-1zylA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bz0 GTP CYCLOHYDROLASE
II

(Escherichia
coli) 		PF00925
(GTP_cyclohydro2) 		4 VAL A  50
LEU A 147
THR A 149
LEU A 171
 None
None
G2P  A1176 (-3.7A)
None
 0.88A 1jgsA-2bz0A:
undetectable		 1jgsA-2bz0A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d3a GLUTAMINE SYNTHETASE

(Zea mays) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		4 PRO A 124
VAL A 206
THR A 344
VAL A 119
 None
 0.99A 1jgsA-2d3aA:
undetectable		 1jgsA-2d3aA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ffi 2-PYRONE-4,6-DICARBO
XYLIC ACID
HYDROLASE, PUTATIVE

(Pseudomonas
putida) 		PF04909
(Amidohydro_2) 		4 PRO A 150
VAL A 151
LEU A 188
VAL A 146
 None
 0.93A 1jgsA-2ffiA:
undetectable		 1jgsA-2ffiA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gcd SERINE/THREONINE-PRO
TEIN KINASE TAO2

(Rattus
norvegicus) 		PF00069
(Pkinase) 		4 VAL A 131
LEU A 218
THR A 214
LEU A 211
 None
 0.76A 1jgsA-2gcdA:
undetectable		 1jgsA-2gcdA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gs5 CONSERVED
HYPOTHETICAL PROTEIN

(Corynebacterium
diphtheriae) 		PF02622
(DUF179) 		4 VAL A  91
LEU A 109
THR A 107
LEU A 106
 None
 0.91A 1jgsA-2gs5A:
undetectable		 1jgsA-2gs5A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hcs RNA-DIRECTED RNA
POLYMERASE (NS5)

(West Nile virus) 		PF00972
(Flavi_NS5) 		4 VAL A 620
LEU A 376
THR A 380
LEU A 383
 None
 0.76A 1jgsA-2hcsA:
2.0		 1jgsA-2hcsA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jzx POLY(RC)-BINDING
PROTEIN 2

(Homo sapiens) 		PF00013
(KH_1) 		4 VAL A 164
THR A  65
LEU A  14
VAL A 159
 None
 0.86A 1jgsA-2jzxA:
undetectable		 1jgsA-2jzxA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l9b MRNA
3'-END-PROCESSING
PROTEIN RNA14
MRNA
3'-END-PROCESSING
PROTEIN RNA15

(Saccharomyces
cerevisiae) 		PF05843
(Suf)
no annotation 		4 VAL B 635
LEU A 205
THR A 209
LEU A 212
 None
 0.53A 1jgsA-2l9bB:
undetectable		 1jgsA-2l9bB:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m0m MINOR AMPULLATE
FIBROIN 1

(Nephila
antipodiana) 		PF11260
(Spidroin_MaSp) 		4 VAL A  82
THR A  24
LEU A  28
VAL A  87
 None
 0.99A 1jgsA-2m0mA:
undetectable		 1jgsA-2m0mA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2na0 GUANYLYL
CYCLASE-ACTIVATING
PROTEIN 1

(Bos taurus) 		PF00036
(EF-hand_1)
PF13499
(EF-hand_7) 		4 VAL A 160
LEU A 167
THR A 171
LEU A 174
 None
 0.79A 1jgsA-2na0A:
undetectable		 1jgsA-2na0A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ogs THERMOSTABLE
CARBOXYLESTERASE
EST50

(Geobacillus
stearothermophilus) 		PF00135
(COesterase) 		4 PRO A 100
VAL A 131
LEU A 102
THR A 189
 PRO  A 100 ( 1.1A)
VAL  A 131 ( 0.6A)
LEU  A 102 ( 0.6A)
THR  A 189 ( 0.8A)
 0.88A 1jgsA-2ogsA:
undetectable		 1jgsA-2ogsA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q6u NIKD PROTEIN

(Streptomyces
tendae) 		PF01266
(DAO) 		4 PRO A  14
VAL A  15
THR A 155
LEU A 156
 FAD  A 401 ( 3.4A)
FAD  A 401 ( 3.8A)
None
None
 1.00A 1jgsA-2q6uA:
undetectable		 1jgsA-2q6uA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q7n LEUKEMIA INHIBITORY
FACTOR RECEPTOR

(Mus musculus) 		PF00041
(fn3) 		4 VAL A 333
THR A 363
LEU A 362
VAL A 349
 None
 0.90A 1jgsA-2q7nA:
undetectable		 1jgsA-2q7nA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rjt BETA-KETOACYL-ACP
SYNTHASE II

(Streptococcus
pneumoniae) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 PRO A 360
VAL A 359
THR A 362
VAL A 349
 None
 0.78A 1jgsA-2rjtA:
undetectable		 1jgsA-2rjtA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bsf AT4G34840

(Arabidopsis
thaliana) 		PF01048
(PNP_UDP_1) 		4 LEU A 228
THR A 232
LEU A 235
VAL A  20
 None
 0.40A 1jgsA-3bsfA:
undetectable		 1jgsA-3bsfA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c2g SYS-1 PROTEIN

(Caenorhabditis
elegans) 		no annotation 4 VAL A 531
LEU A 501
THR A 499
VAL A 490
 None
 0.94A 1jgsA-3c2gA:
undetectable		 1jgsA-3c2gA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3exc UNCHARACTERIZED
PROTEIN

(Sulfolobus
solfataricus) 		PF09827
(CRISPR_Cas2) 		4 VAL X  51
LEU X  18
LEU X  25
ARG X  43
 None
 0.96A 1jgsA-3excX:
undetectable		 1jgsA-3excX:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fmf DETHIOBIOTIN
SYNTHETASE

(Mycobacterium
tuberculosis) 		PF13500
(AAA_26) 		4 PRO A  38
VAL A  39
LEU A  94
VAL A 107
 None
 0.99A 1jgsA-3fmfA:
undetectable		 1jgsA-3fmfA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fyd PROBABLE
DIMETHYLADENOSINE
TRANSFERASE

(Methanocaldococcus
jannaschii) 		PF00398
(RrnaAD) 		4 VAL A  98
LEU A 124
LEU A  44
VAL A  57
 None
 0.87A 1jgsA-3fydA:
undetectable		 1jgsA-3fydA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g3l PUTATIVE
UNCHARACTERIZED
MEMBRANE-ASSOCIATED
PROTEIN

(Bacteroides
fragilis) 		PF12985
(DUF3869) 		4 VAL A 322
LEU A 309
THR A 142
VAL A 305
 None
None
None
GOL  A   8 (-3.7A)
 0.78A 1jgsA-3g3lA:
undetectable		 1jgsA-3g3lA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g5a FMN
ADENYLYLTRANSFERASE

([Candida]
glabrata) 		PF01507
(PAPS_reduct) 		4 VAL A  69
LEU A  73
THR A  14
LEU A  13
 None
 0.94A 1jgsA-3g5aA:
undetectable		 1jgsA-3g5aA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gry DIMETHYLADENOSINE
TRANSFERASE

(Methanocaldococcus
jannaschii) 		PF00398
(RrnaAD) 		4 VAL A  98
LEU A 124
LEU A  44
VAL A  57
 None
None
SAM  A 300 ( 4.7A)
None
 0.89A 1jgsA-3gryA:
undetectable		 1jgsA-3gryA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gsi N,N-DIMETHYLGLYCINE
OXIDASE

(Arthrobacter
globiformis) 		PF01266
(DAO)
PF01571
(GCV_T)
PF08669
(GCV_T_C)
PF16350
(FAO_M) 		4 VAL A 360
THR A 338
LEU A 220
VAL A 356
 None
 0.87A 1jgsA-3gsiA:
undetectable		 1jgsA-3gsiA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY

(Agrobacterium
fabrum) 		PF13377
(Peripla_BP_3) 		4 VAL A 251
THR A 258
LEU A 261
VAL A 276
 None
 0.95A 1jgsA-3gv0A:
undetectable		 1jgsA-3gv0A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i9v NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 4

(Thermus
thermophilus) 		PF00346
(Complex1_49kDa) 		4 VAL 4 187
LEU 4 294
LEU 4 123
VAL 4 163
 None
 0.95A 1jgsA-3i9v4:
undetectable		 1jgsA-3i9v4:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihj ALANINE
AMINOTRANSFERASE 2

(Homo sapiens) 		PF00155
(Aminotran_1_2) 		4 VAL A 507
LEU A 504
THR A 420
LEU A 423
 None
 0.94A 1jgsA-3ihjA:
undetectable		 1jgsA-3ihjA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k2c PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Encephalitozoon
cuniculi) 		PF00160
(Pro_isomerase) 		4 VAL A  24
LEU A  27
ARG A  40
VAL A 168
 None
 0.62A 1jgsA-3k2cA:
undetectable		 1jgsA-3k2cA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k70 EXODEOXYRIBONUCLEASE
V ALPHA CHAIN

(Escherichia
coli) 		PF13538
(UvrD_C_2)
PF13604
(AAA_30) 		4 VAL D 160
LEU D 329
THR D 333
LEU D 141
 None
 0.76A 1jgsA-3k70D:
0.0		 1jgsA-3k70D:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n6r PROPIONYL-COA
CARBOXYLASE, ALPHA
SUBUNIT

(Ruegeria
pomeroyi) 		PF00289
(Biotin_carb_N)
PF00364
(Biotin_lipoyl)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		4 VAL A 370
LEU A 354
LEU A 275
VAL A 367
 None
 0.94A 1jgsA-3n6rA:
undetectable		 1jgsA-3n6rA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ng0 GLUTAMINE SYNTHETASE

(Synechocystis
sp. PCC 6803) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		4 VAL A 443
LEU A 425
LEU A 373
VAL A 437
 None
 0.97A 1jgsA-3ng0A:
0.9		 1jgsA-3ng0A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus) 		PF02626
(CT_A_B)
PF02682
(CT_C_D) 		4 VAL A 366
LEU A 286
THR A 284
LEU A 283
 None
 0.77A 1jgsA-3oepA:
undetectable		 1jgsA-3oepA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3om8 PROBABLE HYDROLASE

(Pseudomonas
aeruginosa) 		PF00561
(Abhydrolase_1) 		4 VAL A 211
LEU A 237
THR A 239
LEU A 240
 None
 0.98A 1jgsA-3om8A:
undetectable		 1jgsA-3om8A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pja TRANSLIN

(Homo sapiens) 		PF01997
(Translin) 		4 VAL A 105
LEU A  42
LEU A 147
VAL A 119
 None
 0.85A 1jgsA-3pjaA:
1.8		 1jgsA-3pjaA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qt4 CATHEPSIN-L-LIKE
MIDGUT CYSTEINE
PROTEINASE

(Tenebrio
molitor) 		PF00112
(Peptidase_C1)
PF08246
(Inhibitor_I29) 		4 VAL A 131
LEU A 145
THR A 143
LEU A 142
 None
None
PG4  A 416 ( 4.8A)
None
 0.86A 1jgsA-3qt4A:
undetectable		 1jgsA-3qt4A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3thn EXONUCLEASE,
PUTATIVE

(Thermotoga
maritima) 		PF00149
(Metallophos) 		4 VAL A  87
LEU A  55
THR A  12
VAL A  50
 None
 0.99A 1jgsA-3thnA:
undetectable		 1jgsA-3thnA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tlm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 1

(Bos taurus) 		PF00122
(E1-E2_ATPase)
PF00689
(Cation_ATPase_C)
PF00690
(Cation_ATPase_N)
PF08282
(Hydrolase_3)
PF13246
(Cation_ATPase) 		4 VAL A 596
LEU A 448
LEU A 410
VAL A 593
 None
 0.94A 1jgsA-3tlmA:
undetectable		 1jgsA-3tlmA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u95 GLYCOSIDE HYDROLASE,
FAMILY 4

(Thermotoga
neapolitana) 		PF02056
(Glyco_hydro_4)
PF11975
(Glyco_hydro_4C) 		4 PRO A 161
VAL A 162
THR A 416
VAL A 136
 None
 0.96A 1jgsA-3u95A:
undetectable		 1jgsA-3u95A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ag9 GLUCOSAMINE-6-PHOSPH
ATE
N-ACETYLTRANSFERASE

(Caenorhabditis
elegans) 		PF00583
(Acetyltransf_1) 		4 VAL A  81
LEU A  39
LEU A 117
VAL A  24
 None
None
COA  A1166 (-4.9A)
None
 0.93A 1jgsA-4ag9A:
undetectable		 1jgsA-4ag9A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bug ANCILLARY PROTEIN 1

(Streptococcus
pyogenes) 		PF08341
(TED) 		4 VAL A 326
LEU A 348
THR A 346
LEU A 345
 None
 0.77A 1jgsA-4bugA:
undetectable		 1jgsA-4bugA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cyb PUTATIVE DNA
PROTECTION PROTEIN

(Streptomyces
coelicolor) 		PF00210
(Ferritin) 		4 VAL A 106
THR A 169
LEU A 172
VAL A  58
 None
 0.90A 1jgsA-4cybA:
2.0		 1jgsA-4cybA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fdh CYTOCHROME P450
11B2, MITOCHONDRIAL

(Homo sapiens) 		PF00067
(p450) 		4 LEU A 369
THR A 326
LEU A 330
VAL A 467
 None
 0.86A 1jgsA-4fdhA:
undetectable		 1jgsA-4fdhA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fnm E3 ALPHA-ESTERASE-7
CARBOXYLESTERASE

(Lucilia cuprina) 		PF00135
(COesterase) 		4 PRO A 128
VAL A 158
LEU A 130
THR A 213
 None
 0.93A 1jgsA-4fnmA:
undetectable		 1jgsA-4fnmA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fzw 2,3-DEHYDROADIPYL-CO
A HYDRATASE

(Escherichia
coli) 		PF00378
(ECH_1) 		4 VAL A  51
LEU A  14
THR A  16
LEU A  17
 None
 0.96A 1jgsA-4fzwA:
undetectable		 1jgsA-4fzwA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hl6 UNCHARACTERIZED
PROTEIN YFDE

(Escherichia
coli) 		PF02515
(CoA_transf_3) 		4 VAL A 241
THR A 244
LEU A 298
VAL A 317
 None
 0.79A 1jgsA-4hl6A:
undetectable		 1jgsA-4hl6A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4is4 GLUTAMINE SYNTHETASE

(Medicago
truncatula) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		4 PRO A 124
VAL A 206
THR A 344
VAL A 119
 None
 0.99A 1jgsA-4is4A:
undetectable		 1jgsA-4is4A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ius GCN5-RELATED
N-ACETYLTRANSFERASE

(Kribbella
flavida) 		PF00583
(Acetyltransf_1) 		4 VAL A  79
LEU A 103
ARG A  41
VAL A  43
 None
 0.95A 1jgsA-4iusA:
undetectable		 1jgsA-4iusA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jlw GLUTATHIONE-INDEPEND
ENT FORMALDEHYDE
DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 VAL A  92
LEU A 149
LEU A 152
VAL A  42
 None
 0.69A 1jgsA-4jlwA:
undetectable		 1jgsA-4jlwA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mfi SN-GLYCEROL-3-PHOSPH
ATE ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN USPB

(Mycobacterium
tuberculosis) 		PF13416
(SBP_bac_8) 		4 VAL A  97
THR A 115
LEU A 114
VAL A  94
 None
 0.89A 1jgsA-4mfiA:
undetectable		 1jgsA-4mfiA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n14 CELL DIVISION CYCLE
PROTEIN 20 HOMOLOG

(Homo sapiens) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		4 VAL A 232
LEU A 241
LEU A 281
VAL A 271
 None
 0.98A 1jgsA-4n14A:
undetectable		 1jgsA-4n14A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o6k INTERLEUKIN 22

(Danio rerio) 		no annotation 4 VAL A  59
THR A 130
LEU A 133
VAL A  86
 None
 0.87A 1jgsA-4o6kA:
undetectable		 1jgsA-4o6kA:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6u UNCHARACTERIZED
PROTEIN

(Mycobacterium
tuberculosis) 		no annotation 4 VAL A  73
THR A  50
LEU A  51
VAL A   8
 None
 0.91A 1jgsA-4q6uA:
undetectable		 1jgsA-4q6uA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qaf LIPOCALIN-1

(Homo sapiens) 		PF00061
(Lipocalin) 		4 VAL A  67
LEU A  44
THR A  42
LEU A  41
 None
None
None
OMA  A 201 ( 4.8A)
 0.72A 1jgsA-4qafA:
undetectable		 1jgsA-4qafA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qh6 CRUZIPAIN

(Trypanosoma
cruzi) 		PF00112
(Peptidase_C1) 		4 VAL A  34
LEU A  48
THR A  46
LEU A  45
 None
 0.77A 1jgsA-4qh6A:
undetectable		 1jgsA-4qh6A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN

(Salmonella
enterica) 		PF00207
(A2M)
PF01835
(A2M_N)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl)
PF11974
(MG1) 		4 VAL A1071
THR A1039
LEU A1038
VAL A1035
 None
 0.90A 1jgsA-4u48A:
undetectable		 1jgsA-4u48A:
6.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zmu DIGUANYLATE CYCLASE

(Pseudomonas
aeruginosa) 		PF00990
(GGDEF)
PF01590
(GAF) 		4 VAL A 341
THR A 273
LEU A 276
VAL A 338
 None
 0.89A 1jgsA-4zmuA:
undetectable		 1jgsA-4zmuA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ac9 VP1

(Foot-and-mouth
disease virus) 		PF00073
(Rhv) 		4 VAL 1  78
LEU 1 115
THR 1 113
LEU 1 112
 None
 0.82A 1jgsA-5ac91:
undetectable		 1jgsA-5ac91:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5auo ATPASE INVOLVED IN
CHROMOSOME
PARTITIONING,
PARA/MIND FAMILY,
MRP HOMOLOG

(Thermococcus
kodakarensis) 		PF10609
(ParA) 		4 VAL B 226
LEU B  35
THR B  39
LEU B  42
 None
ACP  B 301 (-3.9A)
None
None
 0.94A 1jgsA-5auoB:
undetectable		 1jgsA-5auoB:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cxc RIBOSOME BIOGENESIS
PROTEIN ERB1

(Chaetomium
thermophilum) 		PF00400
(WD40) 		4 VAL B 459
LEU B 468
LEU B 513
VAL B 499
 None
 0.94A 1jgsA-5cxcB:
undetectable		 1jgsA-5cxcB:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dzz DESMOPLAKIN

(Homo sapiens) 		PF00681
(Plectin) 		4 PRO A2175
THR A2045
LEU A2048
VAL A2203
 None
 0.90A 1jgsA-5dzzA:
undetectable		 1jgsA-5dzzA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f7h T-CELL
IMMUNOGLOBULIN AND
MUCIN
DOMAIN-CONTAINING
PROTEIN 4

(Homo sapiens) 		no annotation 4 LEU B  79
THR B  77
LEU B  76
VAL B  55
 None
 0.96A 1jgsA-5f7hB:
undetectable		 1jgsA-5f7hB:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h1y PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX41

(Homo sapiens) 		PF00270
(DEAD) 		4 PRO A 238
VAL A 239
LEU A 216
VAL A 234
 None
 0.58A 1jgsA-5h1yA:
undetectable		 1jgsA-5h1yA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hon EXTRACELLULAR
ARABINANASE

(Geobacillus
stearothermophilus) 		PF13385
(Laminin_G_3) 		4 PRO A 742
VAL A 741
THR A 722
LEU A 721
 None
 0.97A 1jgsA-5honA:
undetectable		 1jgsA-5honA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hp6 EXTRACELLULAR
ARABINANASE

(Geobacillus
stearothermophilus) 		PF04616
(Glyco_hydro_43)
PF13385
(Laminin_G_3)
PF16369
(GH43_C) 		4 PRO A 742
VAL A 741
THR A 722
LEU A 721
 None
 0.99A 1jgsA-5hp6A:
undetectable		 1jgsA-5hp6A:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ktl 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE

(Trichormus
variabilis) 		PF00701
(DHDPS) 		4 VAL A 213
LEU A 293
LEU A 259
VAL A 208
 None
 0.82A 1jgsA-5ktlA:
undetectable		 1jgsA-5ktlA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lcw CELL DIVISION CYCLE
PROTEIN 20 HOMOLOG

(Homo sapiens) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		4 VAL Q 232
LEU Q 241
LEU Q 281
VAL Q 271
 None
 0.95A 1jgsA-5lcwQ:
undetectable		 1jgsA-5lcwQ:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lcw CELL DIVISION CYCLE
PROTEIN 20 HOMOLOG

(Homo sapiens) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		4 VAL R 232
LEU R 241
LEU R 281
VAL R 271
 None
 0.95A 1jgsA-5lcwR:
undetectable		 1jgsA-5lcwR:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lpz PROTEIN
BRASSINOSTEROID
INSENSITIVE 1

(Arabidopsis
thaliana) 		PF00069
(Pkinase) 		4 VAL A1074
THR A1081
LEU A1080
VAL A1135
 None
 0.94A 1jgsA-5lpzA:
undetectable		 1jgsA-5lpzA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m0t ALPHA-KETOGLUTARATE-
DEPENDENT NON-HEME
IRON OXYGENASE EASH

(Aspergillus
japonicus) 		PF05721
(PhyH) 		4 VAL A 118
LEU A 158
THR A 156
LEU A 155
 None
 0.72A 1jgsA-5m0tA:
undetectable		 1jgsA-5m0tA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5muu MAJOR OUTER CAPSID
PROTEIN

(Pseudomonas
virus phi6) 		no annotation 4 VAL D  11
THR D  55
LEU D  56
VAL D   6
 None
 0.93A 1jgsA-5muuD:
undetectable		 1jgsA-5muuD:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t3o RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE

(Thermus
thermophilus) 		PF13793
(Pribosyltran_N)
PF14572
(Pribosyl_synth) 		4 VAL A 269
LEU A 283
THR A 285
LEU A 286
 None
 0.95A 1jgsA-5t3oA:
undetectable		 1jgsA-5t3oA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tnu DNA-DEPENDENT ATPASE
XPBII

(Sulfurisphaera
tokodaii) 		no annotation 4 VAL A 104
LEU A 170
LEU A  81
VAL A  99
 None
 0.81A 1jgsA-5tnuA:
undetectable		 1jgsA-5tnuA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uv6 OPIOID-BINDING
PROTEIN/CELL
ADHESION MOLECULE

(Homo sapiens) 		no annotation 4 VAL A  47
LEU A 130
ARG A 162
VAL A 134
 None
 0.94A 1jgsA-5uv6A:
undetectable		 1jgsA-5uv6A:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x2b SULFOTRANSFERASE

(Mus musculus) 		no annotation 4 VAL D  56
LEU D 190
THR D 194
LEU D 197
 None
 0.99A 1jgsA-5x2bD:
undetectable		 1jgsA-5x2bD:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x2o TASTE RECEPTOR, TYPE
1, MEMBER 3

(Oryzias latipes) 		PF01094
(ANF_receptor) 		4 VAL B  78
LEU B 333
THR B 337
LEU B 340
 None
 0.91A 1jgsA-5x2oB:
undetectable		 1jgsA-5x2oB:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xip PROLYL-TRNA
SYNTHETASE, PUTATIVE

(Eimeria tenella) 		no annotation 4 LEU A 406
THR A 513
LEU A 516
VAL A 276
 None
 0.76A 1jgsA-5xipA:
1.8		 1jgsA-5xipA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yjh PERIOSTIN

(Homo sapiens) 		no annotation 4 VAL A 320
THR A 323
LEU A 306
VAL A 340
 None
 0.89A 1jgsA-5yjhA:
undetectable		 1jgsA-5yjhA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6a8m -

(-) 		no annotation 4 VAL A  34
THR A  49
LEU A  52
VAL A  75
 None
 0.86A 1jgsA-6a8mA:
undetectable		 1jgsA-6a8mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b3j GLUCAGON-LIKE
PEPTIDE 1 RECEPTOR

(Homo sapiens) 		no annotation 4 VAL R 332
LEU R 349
THR R 353
LEU R 356
 None
 0.89A 1jgsA-6b3jR:
undetectable		 1jgsA-6b3jR:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c2s TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY

(Rhodopseudomonas
palustris) 		no annotation 4 VAL A  82
THR A  76
LEU A  75
ARG A 118
 None
 0.91A 1jgsA-6c2sA:
15.4		 1jgsA-6c2sA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c4m YERSINOPINE
DEHYDROGENASE

(Yersinia pestis) 		no annotation 5 PRO C 385
LEU C 265
THR C 251
LEU C 255
VAL C 389
 None
 1.05A 1jgsA-6c4mC:
1.5		 1jgsA-6c4mC:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cia ALDO/KETO REDUCTASE

(Klebsiella
pneumoniae) 		no annotation 4 PRO A  15
VAL A  14
LEU A 238
LEU A 256
 None
 0.96A 1jgsA-6ciaA:
undetectable		 1jgsA-6ciaA:
20.28