SIMILAR PATTERNS OF AMINO ACIDS FOR 1J96_B_TESB904_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dgv APO CIB

(Homo sapiens) 		PF13499
(EF-hand_7) 		4 VAL A 182
ILE A 181
GLU A  55
LEU A  53
 None
 1.07A 1j96B-1dgvA:
undetectable		 1j96B-1dgvA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ew3 ALLERGEN EQU C 1

(Equus caballus) 		PF00061
(Lipocalin) 		4 TYR A  75
ILE A  33
GLU A 137
LEU A 101
 None
 0.98A 1j96B-1ew3A:
undetectable		 1j96B-1ew3A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1htd ATROLYSIN C

(Crotalus atrox) 		PF01421
(Reprolysin) 		4 VAL A 126
ILE A 125
HIS A  92
LEU A  86
 None
 0.94A 1j96B-1htdA:
0.0		 1j96B-1htdA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1htt HISTIDYL-TRNA
SYNTHETASE

(Escherichia
coli) 		PF03129
(HGTP_anticodon)
PF13393
(tRNA-synt_His) 		4 TYR A 288
ILE A 140
GLU A 131
LEU A  98
 None
None
HIS  A 450 ( 3.0A)
None
 1.01A 1j96B-1httA:
0.6		 1j96B-1httA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lbk GLUTATHIONE
S-TRANSFERASE CLASS
PI CHIMAERA (CODA)

(Homo sapiens) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A   7
ILE A 161
GLU A 205
LEU A 201
 None
None
GSH  A 504 (-3.3A)
None
 1.09A 1j96B-1lbkA:
undetectable		 1j96B-1lbkA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 ILE A 261
HIS A 221
GLU A 218
LEU A 270
 None
 1.07A 1j96B-1lnzA:
2.5		 1j96B-1lnzA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u8v GAMMA-AMINOBUTYRATE
METABOLISM
DEHYDRATASE/ISOMERAS
E

(Clostridium
aminobutyricum) 		PF03241
(HpaB)
PF11794
(HpaB_N) 		4 TYR A   8
ILE A  35
HIS A 196
LEU A  15
 None
 1.08A 1j96B-1u8vA:
undetectable		 1j96B-1u8vA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ut9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Ruminiclostridium
thermocellum) 		PF00759
(Glyco_hydro_9)
PF02927
(CelD_N) 		4 VAL A 690
ILE A 689
GLU A 570
TRP A 399
 None
 1.06A 1j96B-1ut9A:
undetectable		 1j96B-1ut9A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w8g HYPOTHETICAL UPF0001
PROTEIN YGGS

(Escherichia
coli) 		PF01168
(Ala_racemase_N) 		4 VAL A  63
ILE A  66
HIS A 101
LEU A  32
 None
 1.00A 1j96B-1w8gA:
5.6		 1j96B-1w8gA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wl1 OCTOPRENYL-DIPHOSPHA
TE SYNTHASE

(Thermotoga
maritima) 		PF00348
(polyprenyl_synt) 		4 VAL A 135
ILE A 136
GLU A  71
LEU A  78
 None
 1.01A 1j96B-1wl1A:
undetectable		 1j96B-1wl1A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zun SULFATE
ADENYLYLTRANSFERASE
SUBUNIT 2

(Pseudomonas
syringae) 		PF01507
(PAPS_reduct) 		4 VAL A 205
ILE A 204
GLU A 190
TRP A 194
 None
 1.05A 1j96B-1zunA:
undetectable		 1j96B-1zunA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zuw GLUTAMATE RACEMASE 1

(Bacillus
subtilis) 		PF01177
(Asp_Glu_race) 		4 TYR A 188
VAL A  96
ILE A  97
LEU A 181
 None
 1.09A 1j96B-1zuwA:
undetectable		 1j96B-1zuwA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bxy MALTOOLIGOSYLTREHALO
SE TREHALOHYDROLASE

(Deinococcus
radiodurans) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48)
PF11941
(DUF3459) 		4 TYR A 130
ILE A 396
GLU A 443
LEU A 518
 None
 0.94A 1j96B-2bxyA:
9.2		 1j96B-2bxyA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c0h MANNAN
ENDO-1,4-BETA-MANNOS
IDASE

(Mytilus edulis) 		PF00150
(Cellulase) 		4 TYR A 151
VAL A 229
HIS A  81
LEU A 103
 None
 1.03A 1j96B-2c0hA:
8.9		 1j96B-2c0hA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c6x CITRATE SYNTHASE 1

(Bacillus
subtilis) 		PF00285
(Citrate_synt) 		4 TYR A 309
VAL A 272
GLU A 286
LEU A 224
 None
 1.04A 1j96B-2c6xA:
undetectable		 1j96B-2c6xA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cjw GTP-BINDING PROTEIN
GEM

(Homo sapiens) 		PF00071
(Ras) 		4 VAL A 189
ILE A 218
HIS A  99
LEU A 118
 None
 0.93A 1j96B-2cjwA:
2.5		 1j96B-2cjwA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1

(Saccharomyces
cerevisiae) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF03477
(ATP-cone) 		4 TYR A 143
VAL A 136
ILE A 135
LEU A 156
 None
 0.76A 1j96B-2cvtA:
2.7		 1j96B-2cvtA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dwu GLUTAMATE RACEMASE

(Bacillus
anthracis) 		PF01177
(Asp_Glu_race) 		4 TYR A 191
VAL A  99
ILE A 100
LEU A 184
 None
 1.07A 1j96B-2dwuA:
undetectable		 1j96B-2dwuA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e3x COAGULATION FACTOR
X-ACTIVATING ENZYME
HEAVY CHAIN

(Daboia
siamensis) 		PF00200
(Disintegrin)
PF01421
(Reprolysin)
PF08516
(ADAM_CR) 		4 VAL A 129
ILE A 128
HIS A  95
LEU A  89
 None
 1.00A 1j96B-2e3xA:
undetectable		 1j96B-2e3xA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2erq VASCULAR
APOPTOSIS-INDUCING
PROTEIN 1

(Crotalus atrox) 		PF00200
(Disintegrin)
PF01421
(Reprolysin)
PF08516
(ADAM_CR) 		4 VAL A 319
ILE A 318
HIS A 285
LEU A 279
 None
 0.87A 1j96B-2erqA:
undetectable		 1j96B-2erqA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2go4 UDP-3-O-[3-HYDROXYMY
RISTOYL]
N-ACETYLGLUCOSAMINE
DEACETYLASE

(Aquifex
aeolicus) 		PF03331
(LpxC) 		4 VAL A  96
ILE A  94
GLU A  78
LEU A 249
 None
None
TUX  A 901 (-3.6A)
None
 0.95A 1j96B-2go4A:
undetectable		 1j96B-2go4A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gzm GLUTAMATE RACEMASE

(Bacillus
anthracis) 		PF01177
(Asp_Glu_race) 		4 TYR A 188
VAL A  96
ILE A  97
LEU A 181
 None
 1.07A 1j96B-2gzmA:
undetectable		 1j96B-2gzmA:
23.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ipj ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2

(Homo sapiens) 		PF00248
(Aldo_ket_red) 		6 VAL A 128
ILE A 129
HIS A 222
GLU A 224
TRP A 227
LEU A 306
 None
None
NAP  A   1 ( 4.8A)
None
FFA  A 325 (-3.8A)
FFA  A 325 (-4.8A)
 0.81A 1j96B-2ipjA:
55.5		 1j96B-2ipjA:
99.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j1q ARGININE KINASE

(Trypanosoma
cruzi) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 VAL A  67
ILE A  65
GLU A  87
LEU A 331
 None
 0.98A 1j96B-2j1qA:
undetectable		 1j96B-2j1qA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j3z C2 TOXIN COMPONENT I

(Clostridium
botulinum) 		PF03496
(ADPrib_exo_Tox) 		4 TYR A 174
VAL A  41
GLU A  25
LEU A 151
 None
 1.01A 1j96B-2j3zA:
undetectable		 1j96B-2j3zA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2odp COMPLEMENT C2

(Homo sapiens) 		PF00089
(Trypsin)
PF00092
(VWA) 		4 TYR A 389
VAL A 369
ILE A 372
LEU A 235
 None
 1.04A 1j96B-2odpA:
undetectable		 1j96B-2odpA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q1z ANTI-SIGMA FACTOR
CHRR,
TRANSCRIPTIONAL
ACTIVATOR CHRR

(Rhodobacter
sphaeroides) 		PF12973
(Cupin_7)
PF13490
(zf-HC2) 		4 VAL B 114
ILE B 132
HIS B 143
GLU B 147
 None
None
ZN  B 197 (-4.1A)
ZN  B 197 (-2.2A)
 1.06A 1j96B-2q1zB:
undetectable		 1j96B-2q1zB:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qri H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN K-B ALPHA
CHAIN, BETA-2
MICROGLOBULIN,
OVALBUMIN-DERIVED
PEPTIDE

(Mus musculus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		4 TYR A 159
VAL A  97
ILE A  98
LEU A 109
 None
 1.02A 1j96B-2qriA:
undetectable		 1j96B-2qriA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r0j UBIQUITIN CARRIER
PROTEIN

(Plasmodium
falciparum) 		PF00179
(UQ_con) 		4 TYR A  60
ILE A  88
GLU A   9
LEU A  54
 None
 0.91A 1j96B-2r0jA:
undetectable		 1j96B-2r0jA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA

(Desulfovibrio
vulgaris) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 TYR A 201
VAL A 236
ILE A 327
GLU A 363
 None
 1.03A 1j96B-2v4jA:
undetectable		 1j96B-2v4jA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vvt GLUTAMATE RACEMASE

(Enterococcus
faecalis) 		PF01177
(Asp_Glu_race) 		4 TYR A 188
VAL A  96
ILE A  97
LEU A 181
 None
 1.01A 1j96B-2vvtA:
undetectable		 1j96B-2vvtA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vy0 ENDO-BETA-1,3-GLUCAN
ASE

(Pyrococcus
furiosus) 		PF00722
(Glyco_hydro_16) 		4 VAL A 240
ILE A 228
GLU A 175
LEU A 156
 None
None
MPD  A1299 (-3.4A)
None
 1.04A 1j96B-2vy0A:
undetectable		 1j96B-2vy0A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y35 LD22664P

(Drosophila
melanogaster) 		PF03159
(XRN_N) 		4 VAL A 956
ILE A 957
HIS A 997
LEU A 916
 None
 0.98A 1j96B-2y35A:
undetectable		 1j96B-2y35A:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yr1 3-DEHYDROQUINATE
DEHYDRATASE

(Geobacillus
kaustophilus) 		PF01487
(DHquinase_I) 		4 VAL A 131
ILE A 128
HIS A 147
GLU A  90
 None
 1.03A 1j96B-2yr1A:
9.2		 1j96B-2yr1A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbz CYTOCHROME P450-SU1

(Streptomyces
griseolus) 		PF00067
(p450) 		4 VAL A 116
ILE A 119
HIS A 345
GLU A 282
 None
 1.06A 1j96B-2zbzA:
undetectable		 1j96B-2zbzA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zns GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 1

(Homo sapiens) 		PF10613
(Lig_chan-Glu_bd) 		4 TYR A 718
VAL A 730
ILE A 727
LEU A 659
 None
 0.93A 1j96B-2znsA:
undetectable		 1j96B-2znsA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b8b CYSQ, SULFITE
SYNTHESIS PATHWAY
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF00459
(Inositol_P) 		4 TYR A 122
VAL A 168
ILE A 195
LEU A 158
 None
 0.92A 1j96B-3b8bA:
undetectable		 1j96B-3b8bA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE

(Yersinia
pseudotuberculosis) 		PF01041
(DegT_DnrJ_EryC1) 		4 VAL A 113
ILE A 114
HIS A 166
LEU A 174
 None
 0.79A 1j96B-3bb8A:
undetectable		 1j96B-3bb8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cux MALATE SYNTHASE

(Bacillus
anthracis) 		PF01274
(Malate_synthase) 		4 TYR A 209
VAL A 312
GLU A  90
LEU A  84
 None
 1.01A 1j96B-3cuxA:
5.1		 1j96B-3cuxA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN

(Bothrops
jararaca) 		PF00200
(Disintegrin)
PF01421
(Reprolysin)
PF08516
(ADAM_CR) 		4 VAL A 129
ILE A 128
HIS A  95
LEU A  89
 None
 0.77A 1j96B-3dslA:
undetectable		 1j96B-3dslA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fqd 5'-3'
EXORIBONUCLEASE 2

(Schizosaccharomyces
pombe) 		PF03159
(XRN_N) 		4 TYR A 627
HIS A 208
GLU A 205
LEU A 241
 None
 1.03A 1j96B-3fqdA:
undetectable		 1j96B-3fqdA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g7t ENVELOPE PROTEIN

(Dengue virus) 		PF00869
(Flavi_glycoprot)
PF02832
(Flavi_glycop_C) 		4 ILE A 335
HIS A  27
GLU A  26
LEU A 321
 None
 1.08A 1j96B-3g7tA:
undetectable		 1j96B-3g7tA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hba PUTATIVE
PHOSPHOSUGAR
ISOMERASE

(Shewanella
denitrificans) 		PF01380
(SIS) 		4 TYR A 306
VAL A 258
ILE A 260
LEU A 185
 None
 1.06A 1j96B-3hbaA:
undetectable		 1j96B-3hbaA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hcu UBIQUITIN-CONJUGATIN
G ENZYME E2 N

(Homo sapiens) 		PF00179
(UQ_con) 		4 TYR B  62
ILE B  90
GLU B  11
LEU B  56
 None
 0.85A 1j96B-3hcuB:
undetectable		 1j96B-3hcuB:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hul HOMOSERINE KINASE

(Listeria
monocytogenes) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		4 TYR A 145
VAL A  92
ILE A  95
GLU A 109
 None
 0.95A 1j96B-3hulA:
undetectable		 1j96B-3hulA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hzh CHEMOTAXIS OPERON
PROTEIN (CHEX)

(Borreliella
burgdorferi) 		PF13690
(CheX) 		4 TYR B   5
VAL B 141
ILE B 140
GLU B 137
 None
 0.67A 1j96B-3hzhB:
undetectable		 1j96B-3hzhB:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iay DNA POLYMERASE DELTA
CATALYTIC SUBUNIT

(Saccharomyces
cerevisiae) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		4 VAL A 970
ILE A 973
GLU A 860
LEU A 819
 None
 0.94A 1j96B-3iayA:
undetectable		 1j96B-3iayA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j0h PHIKZ029

(Pseudomonas
virus phiKZ) 		no annotation 4 TYR A 374
VAL A 249
ILE A 248
GLU A 241
 None
 1.06A 1j96B-3j0hA:
undetectable		 1j96B-3j0hA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jby V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1

(Danio rerio) 		PF12940
(RAG1) 		4 TYR A 950
VAL A 837
GLU A 825
LEU A 904
 None
 0.90A 1j96B-3jbyA:
undetectable		 1j96B-3jbyA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jrq PUTATIVE
UNCHARACTERIZED
PROTEIN AT5G46790

(Arabidopsis
thaliana) 		PF10604
(Polyketide_cyc2) 		4 TYR B 147
VAL B 110
ILE B  89
GLU B 171
 A8S  B   1 (-4.7A)
None
None
A8S  B   1 (-3.4A)
 0.88A 1j96B-3jrqB:
undetectable		 1j96B-3jrqB:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mmw ENDOGLUCANASE

(Thermotoga
maritima) 		PF00150
(Cellulase) 		4 VAL A  79
ILE A  80
GLU A 132
LEU A  12
 None
 0.77A 1j96B-3mmwA:
10.6		 1j96B-3mmwA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3msu CITRATE SYNTHASE

(Francisella
tularensis) 		PF00285
(Citrate_synt) 		4 TYR A 251
ILE A  96
HIS A 151
GLU A 158
 CL  A 432 ( 4.3A)
None
None
None
 0.96A 1j96B-3msuA:
undetectable		 1j96B-3msuA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3odg XANTHOSINE
PHOSPHORYLASE

(Yersinia
pseudotuberculosis) 		PF01048
(PNP_UDP_1) 		4 TYR A 172
ILE A  39
HIS A 144
LEU A 230
 None
 0.99A 1j96B-3odgA:
undetectable		 1j96B-3odgA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3omv RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 TYR A 539
VAL A 561
ILE A 557
GLU A 545
 None
 1.06A 1j96B-3omvA:
undetectable		 1j96B-3omvA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3or2 SULFITE REDCUTASE
SUBUNIT ALPHA

(Desulfovibrio
gigas) 		PF01077
(NIR_SIR) 		4 TYR A 201
VAL A 236
ILE A 327
GLU A 363
 None
 1.04A 1j96B-3or2A:
undetectable		 1j96B-3or2A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT

(Escherichia
coli) 		PF01409
(tRNA-synt_2d)
PF02912
(Phe_tRNA-synt_N) 		4 TYR A 194
VAL A 109
ILE A 113
GLU A 132
 None
 1.08A 1j96B-3pcoA:
undetectable		 1j96B-3pcoA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qkw NUCLEOTIDE SUGAR
SYNTHETASE-LIKE
PROTEIN

(Streptococcus
parasanguinis) 		no annotation 4 TYR A 245
ILE A  13
HIS A 156
LEU A 218
 UDP  A 400 (-4.7A)
None
UDP  A 400 (-4.9A)
None
 1.09A 1j96B-3qkwA:
undetectable		 1j96B-3qkwA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qxf ENDOGLUCANASE

(Escherichia
coli) 		PF01270
(Glyco_hydro_8) 		4 ILE A  76
GLU A  29
TRP A  28
LEU A 338
 None
 1.08A 1j96B-3qxfA:
undetectable		 1j96B-3qxfA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s6d PUTATIVE
TRIOSEPHOSPHATE
ISOMERASE

(Coccidioides
immitis) 		PF00121
(TIM) 		4 VAL A 218
GLU A 283
TRP A 253
LEU A  18
 None
 1.07A 1j96B-3s6dA:
2.9		 1j96B-3s6dA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3to3 PETROBACTIN
BIOSYNTHESIS PROTEIN
ASBB

(Bacillus
anthracis) 		PF04183
(IucA_IucC)
PF06276
(FhuF) 		4 TYR A 374
VAL A 329
HIS A 373
GLU A 369
 None
 0.89A 1j96B-3to3A:
undetectable		 1j96B-3to3A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tvt DISKS LARGE 1 TUMOR
SUPPRESSOR PROTEIN

(Drosophila
melanogaster) 		PF00018
(SH3_1)
PF00625
(Guanylate_kin) 		4 TYR A 952
VAL A 788
ILE A 878
GLU A 805
 None
 0.97A 1j96B-3tvtA:
undetectable		 1j96B-3tvtA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3unv ADMH

(Pantoea
agglomerans) 		PF00221
(Lyase_aromatic) 		4 VAL A 277
ILE A 281
GLU A 483
LEU A 506
 None
 0.89A 1j96B-3unvA:
undetectable		 1j96B-3unvA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v8d CHOLESTEROL
7-ALPHA-MONOOXYGENAS
E

(Homo sapiens) 		PF00067
(p450) 		4 TYR A 499
ILE A 152
GLU A 169
LEU A 298
 None
 0.98A 1j96B-3v8dA:
undetectable		 1j96B-3v8dA:
21.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3wg6 CONJUGATED
POLYKETONE REDUCTASE
C1

(Candida
parapsilosis) 		PF00248
(Aldo_ket_red) 		4 TYR A  60
VAL A 119
ILE A  82
LEU A  39
 NDP  A3001 (-4.7A)
None
None
None
 1.07A 1j96B-3wg6A:
34.7		 1j96B-3wg6A:
32.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wiw GLYCOSYL HYDROLASE
FAMILY 88

(Pedobacter
heparinus) 		PF07470
(Glyco_hydro_88) 		4 TYR A 255
VAL A 171
ILE A 220
HIS A 270
 None
 0.92A 1j96B-3wiwA:
undetectable		 1j96B-3wiwA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyy IRON-SULFUR CLUSTER
BINDING PROTEIN

(Carboxydothermus
hydrogenoformans) 		PF00111
(Fer2)
PF14574
(DUF4445) 		4 TYR X 600
VAL X 247
ILE X 248
GLU X 602
 None
None
None
BU3  X1638 (-3.3A)
 0.75A 1j96B-3zyyX:
undetectable		 1j96B-3zyyX:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a3q ALANINE RACEMASE 1

(Staphylococcus
aureus) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 VAL A 150
ILE A 154
HIS A 200
LEU A  83
 None
 0.93A 1j96B-4a3qA:
2.7		 1j96B-4a3qA:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aig ADAMALYSIN II

(Crotalus
adamanteus) 		PF01421
(Reprolysin) 		4 VAL A 126
ILE A 125
HIS A  92
LEU A  86
 None
 0.99A 1j96B-4aigA:
undetectable		 1j96B-4aigA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4az1 TYROSINE SPECIFIC
PROTEIN PHOSPHATASE

(Trypanosoma
cruzi) 		PF00102
(Y_phosphatase) 		4 TYR A  75
VAL A 223
GLU A 110
LEU A 151
 None
 0.93A 1j96B-4az1A:
undetectable		 1j96B-4az1A:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bju N-ACETYLGLUCOSAMINE-
PHOSPHATE MUTASE

(Aspergillus
fumigatus) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I) 		4 TYR A 292
VAL A 243
ILE A 242
GLU A 436
 None
 0.86A 1j96B-4bjuA:
undetectable		 1j96B-4bjuA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bp8 OLIGOPEPTIDASE B

(Trypanosoma
brucei) 		PF00326
(Peptidase_S9)
PF02897
(Peptidase_S9_N) 		4 VAL A 632
HIS A  57
GLU A  61
LEU A  44
 None
 1.06A 1j96B-4bp8A:
undetectable		 1j96B-4bp8A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c79 SMOOTHENED

(Danio rerio) 		PF01392
(Fz) 		4 VAL A  99
ILE A 100
GLU A 136
TRP A 141
 None
 0.80A 1j96B-4c79A:
undetectable		 1j96B-4c79A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dkw LARGE TERMINASE
PROTEIN

(Salmonella
virus P22) 		PF17289
(Terminase_6C) 		4 VAL A 413
ILE A 417
GLU A 441
LEU A 344
 None
 0.91A 1j96B-4dkwA:
undetectable		 1j96B-4dkwA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hde SCO1/SENC FAMILY
LIPOPROTEIN

(Bacillus
anthracis) 		PF02630
(SCO1-SenC) 		4 TYR A 163
VAL A 101
ILE A 136
LEU A  37
 None
 1.00A 1j96B-4hdeA:
undetectable		 1j96B-4hdeA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hpv S-ADENOSYLMETHIONINE
SYNTHASE

(Sulfolobus
solfataricus) 		PF01941
(AdoMet_Synthase) 		4 VAL A 107
ILE A 110
GLU A  39
LEU A 397
 None
 1.05A 1j96B-4hpvA:
undetectable		 1j96B-4hpvA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m1e PURINE NUCLEOSIDE
PHOSPHORYLASE

(Planctopirus
limnophila) 		PF01048
(PNP_UDP_1) 		4 TYR A 161
ILE A  28
HIS A 133
LEU A 219
 None
 1.09A 1j96B-4m1eA:
undetectable		 1j96B-4m1eA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4me7 ANTITOXIN ENDOAI
MRNA INTERFERASE
ENDOA

(Bacillus
subtilis) 		PF01402
(RHH_1)
PF02452
(PemK_toxin) 		4 VAL A  28
HIS E  76
GLU E  79
LEU A  13
 None
 0.98A 1j96B-4me7A:
undetectable		 1j96B-4me7A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mew SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
REGULATORY SUBUNIT
B'' SUBUNIT BETA

(Homo sapiens) 		PF13499
(EF-hand_7) 		4 VAL A 318
ILE A 319
GLU A 384
LEU A 339
 None
 1.08A 1j96B-4mewA:
undetectable		 1j96B-4mewA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nle ADENYLOSUCCINATE
LYASE

(Mycolicibacterium
smegmatis) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		4 TYR A 468
HIS A 124
GLU A 343
LEU A 120
 None
 1.05A 1j96B-4nleA:
undetectable		 1j96B-4nleA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ojx 3',5'-CYCLIC-NUCLEOT
IDE
PHOSPHODIESTERASE 1

(Saccharomyces
cerevisiae) 		PF02112
(PDEase_II) 		4 VAL A 322
ILE A 276
TRP A 261
LEU A 310
 None
 1.01A 1j96B-4ojxA:
undetectable		 1j96B-4ojxA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qiw DNA-DIRECTED RNA
POLYMERASE
DNA-DIRECTED RNA
POLYMERASE SUBUNIT N

(Thermococcus
kodakarensis) 		PF00562
(RNA_pol_Rpb2_6)
PF01194
(RNA_pol_N)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		4 TYR N  43
ILE B 992
GLU B 972
LEU B 961
 None
 1.08A 1j96B-4qiwN:
undetectable		 1j96B-4qiwN:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ru4 TAIL SPIKE PROTEIN
GP49

(Pseudomonas
virus LKA1) 		PF13229
(Beta_helix) 		4 TYR A 623
VAL A 539
ILE A 538
LEU A 633
 None
 1.09A 1j96B-4ru4A:
undetectable		 1j96B-4ru4A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v1d SINGLE CHAIN
ANTIBODY FRAGMENT
RU1, LIGHT CHAIN

(Homo sapiens) 		PF07686
(V-set) 		4 VAL E 157
ILE E 215
GLU E 221
LEU E 179
 None
 0.91A 1j96B-4v1dE:
undetectable		 1j96B-4v1dE:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v23 MATRIX PROTEIN

(Respiratory
syncytial virus) 		PF03393
(Pneumo_matrix) 		4 TYR A 236
VAL A 153
ILE A 152
GLU A   2
 None
 0.89A 1j96B-4v23A:
undetectable		 1j96B-4v23A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1

(Mus musculus) 		PF12940
(RAG1) 		4 TYR B 928
VAL B 815
GLU B 803
LEU B 882
 None
 1.04A 1j96B-4wwxB:
undetectable		 1j96B-4wwxB:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y67 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE,
APICOPLAST

(Plasmodium
falciparum) 		PF02670
(DXP_reductoisom)
PF08436
(DXP_redisom_C)
PF13288
(DXPR_C) 		4 VAL A 178
ILE A 179
GLU A 318
LEU A 252
 None
 0.98A 1j96B-4y67A:
undetectable		 1j96B-4y67A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e2g BETA-LACTAMASE

(Burkholderia
cenocepacia) 		PF00144
(Beta-lactamase) 		4 TYR A 145
ILE A  57
HIS A 107
GLU A 267
 None
 1.02A 1j96B-5e2gA:
undetectable		 1j96B-5e2gA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e9u GLYCOSYLTRANSFERASE
GTF1

(Streptococcus
gordonii) 		PF00534
(Glycos_transf_1) 		4 TYR A 187
VAL A 227
ILE A 224
GLU A 184
 None
 1.01A 1j96B-5e9uA:
undetectable		 1j96B-5e9uA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eco GLUTATHIONE
S-TRANSFERASE U20

(Arabidopsis
thaliana) 		PF02798
(GST_N)
PF13410
(GST_C_2) 		4 TYR B  32
ILE B 205
GLU B  34
TRP B  11
 None
 1.04A 1j96B-5ecoB:
undetectable		 1j96B-5ecoB:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h1z PUTATIVE CYP ALKANE
HYDROXYLASE
CYP153D17

(Sphingomonas
sp. PAMC 26605) 		PF00067
(p450) 		4 TYR A  48
VAL A   7
ILE A   8
LEU A  31
 None
 0.95A 1j96B-5h1zA:
undetectable		 1j96B-5h1zA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kf2 PREDICTED
ACETYLTRANSFERASE

(Clostridium
acetobutylicum) 		PF00583
(Acetyltransf_1) 		4 TYR A  24
VAL A 285
ILE A 151
GLU A 128
 None
 0.84A 1j96B-5kf2A:
undetectable		 1j96B-5kf2A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lm7 TRANSCRIPTION
TERMINATION/ANTITERM
INATION PROTEIN NUSA

(Escherichia
coli) 		PF00575
(S1)
PF08529
(NusA_N)
PF13184
(KH_5) 		4 VAL A 284
ILE A 285
HIS A 348
LEU A 344
 None
 0.99A 1j96B-5lm7A:
undetectable		 1j96B-5lm7A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ltm PHENYLALANINE
AMMONIA LYASE

(Anabaena) 		no annotation 4 VAL B 559
ILE B 562
HIS B 385
LEU B 319
 None
 1.03A 1j96B-5ltmB:
undetectable		 1j96B-5ltmB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vgm DIHYDROOROTASE

(Vibrio cholerae) 		PF01979
(Amidohydro_1) 		4 TYR A  32
VAL A  14
GLU A 272
LEU A 287
 None
 1.01A 1j96B-5vgmA:
6.7		 1j96B-5vgmA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xv7 SERINE-ARGININE (SR)
PROTEIN KINASE 1

(Homo sapiens) 		no annotation 4 TYR A 517
VAL A 196
ILE A 193
GLU A 543
 None
 0.99A 1j96B-5xv7A:
undetectable		 1j96B-5xv7A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aqo HYPOXANTHINE-GUANINE
PHOSPHORIBOSYLTRANSF
ERASE

(Trypanosoma
brucei) 		no annotation 4 VAL A  85
ILE A  83
GLU A 191
LEU A  51
 None
 1.09A 1j96B-6aqoA:
undetectable		 1j96B-6aqoA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1

(Mus musculus) 		no annotation 4 TYR A 928
VAL A 815
GLU A 803
LEU A 882
 None
 0.98A 1j96B-6cg0A:
undetectable		 1j96B-6cg0A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dbr -

(-) 		no annotation 4 TYR A 950
VAL A 837
GLU A 825
LEU A 904
 None
 0.94A 1j96B-6dbrA:
undetectable		 1j96B-6dbrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6elq CARBON MONOXIDE
DEHYDROGENASE

(Carboxydothermus
hydrogenoformans) 		no annotation 4 VAL X  11
ILE X  12
HIS X 259
LEU X 338
 None
 0.96A 1j96B-6elqX:
undetectable		 1j96B-6elqX:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6emk SERINE/THREONINE-PRO
TEIN KINASE TOR2

(Saccharomyces
cerevisiae) 		no annotation 4 ILE A 415
HIS A 494
GLU A 497
LEU A 485
 None
 1.05A 1j96B-6emkA:
undetectable		 1j96B-6emkA:
11.97