SIMILAR PATTERNS OF AMINO ACIDS FOR 1ISM_B_NCAB305
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b1y | PROTEIN(BETA-AMYLASE) (Hordeum vulgare) |
PF01373(Glyco_hydro_14) | 4 | HIS A 271LEU A 133ASP A 138PHE A 90 | None | 1.12A | 1ismB-1b1yA:0.8 | 1ismB-1b1yA:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1btc | BETA-AMYLASE (Glycine max) |
PF01373(Glyco_hydro_14) | 4 | HIS A 273LEU A 135ASP A 140PHE A 92 | None | 1.07A | 1ismB-1btcA:1.2 | 1ismB-1btcA:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fch | PEROXISOMALTARGETING SIGNAL 1RECEPTOR (Homo sapiens) |
PF13374(TPR_10)PF13432(TPR_16) | 4 | LEU A 595SER A 592ASP A 590PHE A 598 | None | 1.27A | 1ismB-1fchA:undetectable | 1ismB-1fchA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g65 | PROTEASOME COMPONENTPUP3 (Saccharomycescerevisiae) |
PF00227(Proteasome) | 4 | LEU I 134SER I 131ASP I 132PHE I 124 | None MG I 201 (-2.2A)NoneNone | 1.24A | 1ismB-1g65I:undetectable | 1ismB-1g65I:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ghs | 1,3-BETA-GLUCANASE (Hordeum vulgare) |
PF00332(Glyco_hydro_17) | 4 | HIS A 257LEU A 205SER A 204ASP A 207 | None | 1.16A | 1ismB-1ghsA:undetectable | 1ismB-1ghsA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ghs | 1,3-BETA-GLUCANASE (Hordeum vulgare) |
PF00332(Glyco_hydro_17) | 4 | LEU A 205SER A 204ASP A 207PHE A 130 | None | 1.28A | 1ismB-1ghsA:undetectable | 1ismB-1ghsA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i9z | PHOSPHATIDYLINOSITOLPHOSPHATEPHOSPHATASE (Schizosaccharomycespombe) |
PF03372(Exo_endo_phos) | 4 | LEU A 761SER A 762TRP A 814PHE A 790 | None | 1.04A | 1ismB-1i9zA:undetectable | 1ismB-1i9zA:20.68 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ism | BONE MARROW STROMALCELL ANTIGEN 1 (Homo sapiens) |
PF02267(Rib_hydrolayse) | 7 | TRP A 77HIS A 81LEU A 97SER A 98ASP A 107TRP A 140PHE A 173 | NCA A 303 (-4.4A)NCA A 303 (-4.1A)NCA A 303 (-4.3A)NCA A 303 (-3.9A)NCA A 303 (-4.4A)NCA A 303 (-4.0A)NCA A 303 (-3.7A) | 0.12A | 1ismB-1ismA:40.7 | 1ismB-1ismA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iv3 | 2-C-METHYL-D-ERYTHRITOL2,4-CYCLODIPHOSPHATESYNTHASE (Thermusthermophilus) |
PF02542(YgbB) | 4 | HIS A 42SER A 35ASP A 36PHE A 61 | MG A1561 (-3.0A) MG A1561 ( 4.7A)NoneNone | 1.27A | 1ismB-1iv3A:1.5 | 1ismB-1iv3A:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lu2 | LECTIN (Vignaunguiculata) |
PF00139(Lectin_legB) | 4 | HIS A 138LEU A 127SER A 128ASP A 133 | MN A 302 (-3.7A)A2G A 254 ( 4.6A)None CA A 301 ( 3.0A) | 1.29A | 1ismB-1lu2A:undetectable | 1ismB-1lu2A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lyb | CATHEPSIN D (Homo sapiens) |
PF00026(Asp) | 4 | HIS A 77LEU A 83SER A 84ASP A 75 | None | 1.24A | 1ismB-1lybA:undetectable | 1ismB-1lybA:17.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ow0 | IMMUNOGLOBULIN ALPHAFC RECEPTOR (Homo sapiens) |
no annotation | 4 | LEU C 123SER C 122ASP C 110PHE C 106 | NoneNAG C 740 (-3.4A)NAG C 740 (-4.6A)None | 1.25A | 1ismB-1ow0C:undetectable | 1ismB-1ow0C:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rqb | TRANSCARBOXYLASE 5SSUBUNIT (Propionibacteriumfreudenreichii) |
PF00682(HMGL-like)PF02436(PYC_OADA) | 4 | HIS A 217LEU A 28SER A 27ASP A 23 | CO A 529 (-3.3A)NoneNone CO A 529 (-2.5A) | 1.16A | 1ismB-1rqbA:undetectable | 1ismB-1rqbA:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ufa | TT1467 PROTEIN (Thermusthermophilus) |
PF03065(Glyco_hydro_57)PF09210(DUF1957) | 4 | HIS A 300LEU A 295SER A 296ASP A 90 | None | 1.15A | 1ismB-1ufaA:undetectable | 1ismB-1ufaA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1usy | ATPPHOSPHORIBOSYLTRANSFERASE REGULATORYSUBUNIT (Thermotogamaritima) |
PF13393(tRNA-synt_His) | 4 | LEU C 103SER C 102ASP C 105PHE C 211 | None | 0.94A | 1ismB-1usyC:undetectable | 1ismB-1usyC:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vlp | NICOTINATEPHOSPHORIBOSYLTRANSFERASE (Saccharomycescerevisiae) |
PF04095(NAPRTase) | 4 | HIS A 232SER A 297ASP A 296PHE A 278 | None | 1.09A | 1ismB-1vlpA:undetectable | 1ismB-1vlpA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y8c | S-ADENOSYLMETHIONINE-DEPENDENTMETHYLTRANSFERASE (Clostridiumacetobutylicum) |
PF13649(Methyltransf_25) | 4 | LEU A 56SER A 25ASP A 26PHE A 39 | None | 1.25A | 1ismB-1y8cA:undetectable | 1ismB-1y8cA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yir | NICOTINATEPHOSPHORIBOSYLTRANSFERASE 2 (Pseudomonasaeruginosa) |
PF04095(NAPRTase) | 4 | HIS A 226SER A 290ASP A 289PHE A 271 | SO4 A2001 (-3.7A)NoneSO4 A2001 ( 4.2A)None | 1.15A | 1ismB-1yirA:undetectable | 1ismB-1yirA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zuo | HYPOTHETICAL PROTEINLOC92912 (Homo sapiens) |
PF00179(UQ_con) | 4 | LEU A 236SER A 235ASP A 238PHE A 278 | None | 1.17A | 1ismB-1zuoA:undetectable | 1ismB-1zuoA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aaa | ALPHA-AMYLASE (Aspergillusniger) |
PF00128(Alpha-amylase)PF09260(DUF1966) | 4 | TRP A 348SER A 25ASP A 23PHE A 19 | None | 1.16A | 1ismB-2aaaA:undetectable | 1ismB-2aaaA:18.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c0l | PEROXISOMALTARGETING SIGNAL 1RECEPTOR (Homo sapiens) |
PF00515(TPR_1)PF13432(TPR_16) | 4 | LEU A 632SER A 629ASP A 627PHE A 635 | None | 1.25A | 1ismB-2c0lA:undetectable | 1ismB-2c0lA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c11 | MEMBRANE COPPERAMINE OXIDASE (Homo sapiens) |
PF01179(Cu_amine_oxid)PF02727(Cu_amine_oxidN2)PF02728(Cu_amine_oxidN3) | 4 | HIS A 167LEU A 164ASP A 652PHE A 129 | CU A1742 (-3.2A)NoneNoneNone | 1.07A | 1ismB-2c11A:undetectable | 1ismB-2c11A:15.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c11 | MEMBRANE COPPERAMINE OXIDASE (Homo sapiens) |
PF01179(Cu_amine_oxid)PF02727(Cu_amine_oxidN2)PF02728(Cu_amine_oxidN3) | 4 | HIS A 242LEU A 516SER A 497PHE A 501 | None | 0.98A | 1ismB-2c11A:undetectable | 1ismB-2c11A:15.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d4v | ISOCITRATEDEHYDROGENASE (Acidithiobacillusthiooxidans) |
PF00180(Iso_dh) | 4 | LEU A 341SER A 342ASP A 343PHE A 152 | None | 1.26A | 1ismB-2d4vA:undetectable | 1ismB-2d4vA:20.98 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2eg9 | ADP-RIBOSYL CYCLASE1 (Mus musculus) |
PF02267(Rib_hydrolayse) | 4 | TRP A 129LEU A 149ASP A 159TRP A 193 | None | 0.86A | 1ismB-2eg9A:9.5 | 1ismB-2eg9A:32.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hpi | DNA POLYMERASE IIIALPHA SUBUNIT (Thermusaquaticus) |
PF02811(PHP)PF07733(DNA_pol3_alpha)PF14579(HHH_6) | 4 | LEU A 625SER A 469ASP A 470PHE A 668 | None | 1.17A | 1ismB-2hpiA:2.3 | 1ismB-2hpiA:13.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jd4 | LAMININ SUBUNITALPHA-1 (Mus musculus) |
PF00054(Laminin_G_1)PF02210(Laminin_G_2) | 4 | HIS A3053LEU A3028ASP A3040PHE A2880 | None | 1.21A | 1ismB-2jd4A:undetectable | 1ismB-2jd4A:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lnv | GENERAL SECRETIONPATHWAY PROTEIN C (Dickeyadadantii) |
PF11356(T2SSC) | 4 | LEU A 95SER A 96ASP A 161PHE A 120 | None | 1.15A | 1ismB-2lnvA:undetectable | 1ismB-2lnvA:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ntb | PECTINESTERASE A (Dickeyadadantii) |
PF01095(Pectinesterase) | 4 | TRP A 107LEU A 100SER A 105ASP A 103 | None | 1.24A | 1ismB-2ntbA:undetectable | 1ismB-2ntbA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nx9 | OXALOACETATEDECARBOXYLASE 2,SUBUNIT ALPHA (Vibrio cholerae) |
PF00682(HMGL-like)PF02436(PYC_OADA) | 4 | HIS A 209LEU A 22SER A 21ASP A 17 | ZN A 601 (-3.4A)NoneNone ZN A 601 (-2.6A) | 1.14A | 1ismB-2nx9A:undetectable | 1ismB-2nx9A:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o69 | IRON-UTILIZATIONPERIPLASMIC PROTEIN (Haemophilusinfluenzae) |
PF01547(SBP_bac_1) | 4 | HIS A 298LEU A 149SER A 150ASP A 155 | None | 0.98A | 1ismB-2o69A:undetectable | 1ismB-2o69A:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pmp | 2-C-METHYL-D-ERYTHRITOL2,4-CYCLODIPHOSPHATESYNTHASE (Arabidopsisthaliana) |
PF02542(YgbB) | 4 | HIS A 45SER A 38ASP A 39PHE A 64 | ZN A 500 (-3.1A) ZN A 500 ( 4.6A)NoneNone | 1.21A | 1ismB-2pmpA:undetectable | 1ismB-2pmpA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q0x | UNCHARACTERIZEDPROTEIN (Trypanosomabrucei) |
PF08538(DUF1749) | 4 | LEU A 51SER A 50TRP A 43PHE A 70 | None | 1.06A | 1ismB-2q0xA:undetectable | 1ismB-2q0xA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qf7 | PYRUVATE CARBOXYLASEPROTEIN (Rhizobium etli) |
PF00289(Biotin_carb_N)PF00364(Biotin_lipoyl)PF00682(HMGL-like)PF02436(PYC_OADA)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | HIS A 749LEU A 554SER A 553ASP A 549 | ZN A1157 (-3.3A)NoneNone ZN A1157 (-2.6A) | 1.18A | 1ismB-2qf7A:undetectable | 1ismB-2qf7A:13.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qmw | PREPHENATEDEHYDRATASE (Staphylococcusaureus) |
PF00800(PDT) | 4 | LEU A 214SER A 215ASP A 236PHE A 188 | None | 1.15A | 1ismB-2qmwA:undetectable | 1ismB-2qmwA:23.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rch | CYTOCHROME P450 74A (Arabidopsisthaliana) |
PF00067(p450) | 5 | HIS A 342LEU A 513SER A 512ASP A 496PHE A 489 | None | 1.18A | 1ismB-2rchA:undetectable | 1ismB-2rchA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vxb | DNA REPAIR PROTEINRHP9 (Schizosaccharomycespombe) |
PF00533(BRCT) | 4 | LEU A 158SER A 157ASP A 160PHE A 61 | None | 1.05A | 1ismB-2vxbA:undetectable | 1ismB-2vxbA:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x60 | MANNOSE-1-PHOSPHATEGUANYLYLTRANSFERASE (Thermotogamaritima) |
PF00483(NTP_transferase) | 4 | HIS A 110LEU A 7ASP A 109PHE A 193 | NoneGTP A 601 (-3.7A)GTP A 601 ( 3.7A)None | 1.27A | 1ismB-2x60A:undetectable | 1ismB-2x60A:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z3k | LEUCYL/PHENYLALANYL-TRNA-PROTEINTRANSFERASE (Escherichiacoli) |
PF03588(Leu_Phe_trans) | 4 | LEU A 38SER A 34ASP A 32TRP A 58 | None | 0.99A | 1ismB-2z3kA:undetectable | 1ismB-2z3kA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a79 | TOLL-LIKE RECEPTOR6, VARIABLELYMPHOCYTE RECEPTORB (Eptatretusburgeri;Mus musculus) |
PF11921(DUF3439)PF13855(LRR_8) | 4 | LEU B 153SER B 154ASP B 177PHE B 150 | None | 1.19A | 1ismB-3a79B:2.2 | 1ismB-3a79B:18.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b1f | PUTATIVE PREPHENATEDEHYDROGENASE (Streptococcusmutans) |
PF02153(PDH) | 4 | HIS A 26LEU A 166SER A 167ASP A 164 | None | 1.17A | 1ismB-3b1fA:3.0 | 1ismB-3b1fA:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bg9 | PYRUVATECARBOXYLASE,MITOCHONDRIAL (Homo sapiens) |
PF00682(HMGL-like)PF02436(PYC_OADA) | 4 | HIS A 773LEU A 577SER A 576ASP A 572 | MN A2001 (-3.8A)NoneNone MN A2001 (-3.0A) | 1.17A | 1ismB-3bg9A:undetectable | 1ismB-3bg9A:17.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dh0 | SAM DEPENDENTMETHYLTRANSFERASE (Aquifexaeolicus) |
PF13847(Methyltransf_31) | 4 | LEU A 21SER A 19ASP A 17PHE A 24 | None | 1.22A | 1ismB-3dh0A:undetectable | 1ismB-3dh0A:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dzb | PREPHENATEDEHYDROGENASE (Streptococcusthermophilus) |
PF02153(PDH) | 4 | HIS A 26LEU A 166SER A 167ASP A 164 | None | 1.16A | 1ismB-3dzbA:2.4 | 1ismB-3dzbA:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eq5 | SKI-LIKE PROTEIN (Homo sapiens) |
PF02437(Ski_Sno) | 4 | LEU A 202SER A 199ASP A 200PHE A 213 | None | 1.15A | 1ismB-3eq5A:undetectable | 1ismB-3eq5A:15.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3gc6 | ECTO-NAD+GLYCOHYDROLASE (CD38MOLECULE) (Bos taurus) |
PF02267(Rib_hydrolayse) | 4 | TRP A 118LEU A 137ASP A 147TRP A 181 | None | 0.42A | 1ismB-3gc6A:27.4 | 1ismB-3gc6A:33.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hjc | HEAT SHOCK PROTEIN83-1 (Leishmaniamajor) |
PF00183(HSP90) | 4 | LEU A 210SER A 206ASP A 205PHE A 215 | None | 1.25A | 1ismB-3hjcA:undetectable | 1ismB-3hjcA:18.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ho8 | PYRUVATE CARBOXYLASE (Staphylococcusaureus) |
PF00289(Biotin_carb_N)PF00682(HMGL-like)PF02436(PYC_OADA)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | HIS A 773LEU A 577SER A 576ASP A 572 | MN A2002 (-3.4A)NoneNone MN A2002 (-2.7A) | 1.26A | 1ismB-3ho8A:undetectable | 1ismB-3ho8A:11.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3i9k | ADP-RIBOSYL CYCLASE (Aplysiacalifornica) |
PF02267(Rib_hydrolayse) | 4 | TRP A 77LEU A 97TRP A 140PHE A 174 | None | 0.31A | 1ismB-3i9kA:28.5 | 1ismB-3i9kA:32.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ife | PEPTIDASE T (Bacillusanthracis) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 4 | HIS A 79LEU A 77ASP A 199PHE A 172 | ZN A 411 (-3.3A)None ZN A 411 (-1.9A)None | 1.28A | 1ismB-3ifeA:undetectable | 1ismB-3ifeA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3men | ACETYLPOLYAMINEAMINOHYDROLASE (Burkholderiapseudomallei) |
PF00850(Hist_deacetyl) | 4 | HIS A 156LEU A 278SER A 277ASP A 190 | SO4 A 401 (-3.6A)NoneNone K A 402 (-3.0A) | 1.04A | 1ismB-3menA:undetectable | 1ismB-3menA:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3os4 | NICOTINATEPHOSPHORIBOSYLTRANSFERASE (Yersinia pestis) |
PF04095(NAPRTase) | 4 | HIS A 221LEU A 370SER A 371ASP A 259 | None | 0.87A | 1ismB-3os4A:undetectable | 1ismB-3os4A:23.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p1u | SUSD HOMOLOG (Parabacteroidesdistasonis) |
PF12741(SusD-like) | 4 | TRP A 541LEU A 164SER A 163ASP A 166 | None | 1.26A | 1ismB-3p1uA:undetectable | 1ismB-3p1uA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p5p | TAXADIENE SYNTHASE (Taxusbrevifolia) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 4 | LEU A 640SER A 638ASP A 636PHE A 628 | None | 1.05A | 1ismB-3p5pA:undetectable | 1ismB-3p5pA:16.49 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3p5s | CD38 MOLECULE (Bos taurus) |
PF02267(Rib_hydrolayse) | 4 | TRP A 118LEU A 137ASP A 147TRP A 181 | AVU A 280 (-3.8A)AVU A 280 (-3.7A)AVU A 280 (-3.9A)AVU A 280 (-3.6A) | 0.35A | 1ismB-3p5sA:27.4 | 1ismB-3p5sA:33.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q9c | ACETYLPOLYAMINEAMIDOHYDROLASE (Mycoplanaramosa) |
PF00850(Hist_deacetyl) | 4 | HIS A 158LEU A 281SER A 280ASP A 193 | Q9C A 401 (-4.2A)NoneNone K A 342 (-3.2A) | 1.04A | 1ismB-3q9cA:undetectable | 1ismB-3q9cA:19.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3rom | ADP-RIBOSYL CYCLASE1 (Homo sapiens) |
PF02267(Rib_hydrolayse) | 4 | TRP A 125LEU A 145ASP A 155TRP A 189 | 48Z A 301 (-3.6A)48Z A 301 ( 4.8A)NoneNone | 0.34A | 1ismB-3romA:28.4 | 1ismB-3romA:34.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s38 | CYTOCHROME C OXIDASESUBUNIT 2 (Thermusthermophilus) |
PF00116(COX2)PF09125(COX2-transmemb) | 4 | HIS B 114LEU B 84SER B 109ASP B 111 | CUA B 802 (-3.0A)NoneNoneNone | 1.25A | 1ismB-3s38B:undetectable | 1ismB-3s38B:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s6b | METHIONINEAMINOPEPTIDASE (Plasmodiumfalciparum) |
PF00557(Peptidase_M24) | 4 | LEU A 68SER A 69ASP A 137PHE A 162 | None | 1.12A | 1ismB-3s6bA:undetectable | 1ismB-3s6bA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3slz | GAG-PRO-POLPOLYPROTEIN (Murine leukemiavirus) |
PF00077(RVP) | 4 | HIS A 80LEU A 83SER A 38ASP A 96 | FMT A 127 (-3.4A)NoneNoneNone | 1.10A | 1ismB-3slzA:undetectable | 1ismB-3slzA:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vm7 | ALPHA-AMYLASE (Malbrancheacinnamomea) |
PF00128(Alpha-amylase)PF09260(DUF1966) | 4 | TRP A 367SER A 46ASP A 44PHE A 40 | None | 1.20A | 1ismB-3vm7A:undetectable | 1ismB-3vm7A:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vzb | SPHINGOSINE KINASE 1 (Homo sapiens) |
PF00781(DAGK_cat) | 4 | HIS A 156LEU A 153SER A 154ASP A 235 | None | 1.29A | 1ismB-3vzbA:undetectable | 1ismB-3vzbA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wjo | OCTAPRENYLDIPHOSPHATE SYNTHASE (Escherichiacoli) |
PF00348(polyprenyl_synt) | 4 | HIS A 66LEU A 54ASP A 13TRP A 307 | None | 1.26A | 1ismB-3wjoA:undetectable | 1ismB-3wjoA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ag4 | EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1 (Homo sapiens) |
PF00754(F5_F8_type_C) | 4 | TRP A 356LEU A 357TRP A 258PHE A 263 | None | 1.21A | 1ismB-4ag4A:undetectable | 1ismB-4ag4A:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c0t | LIKELY PROTEINKINASE (Candidaalbicans) |
PF00069(Pkinase) | 4 | LEU A 304SER A 303ASP A 319PHE A 306 | None | 0.90A | 1ismB-4c0tA:undetectable | 1ismB-4c0tA:14.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4es1 | BH0342 PROTEIN (Bacillushalodurans) |
PF09827(CRISPR_Cas2) | 4 | LEU A 66SER A 65ASP A 8PHE A 39 | None | 1.25A | 1ismB-4es1A:undetectable | 1ismB-4es1A:16.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fbq | DNA REPAIR ANDTELOMERE MAINTENANCEPROTEIN NBS1,DNAREPAIR PROTEIN RAD32CHIMERIC PROTEIN (Schizosaccharomycespombe) |
PF00149(Metallophos)PF04152(Mre11_DNA_bind) | 4 | HIS A1222LEU A1062SER A1024ASP A1025 | MN A1501 (-3.6A)NoneNone MN A1502 (-3.2A) | 0.84A | 1ismB-4fbqA:undetectable | 1ismB-4fbqA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fcx | DNA REPAIR PROTEINRAD32 (Schizosaccharomycespombe) |
no annotation | 4 | HIS B 222LEU B 62SER B 24ASP B 25 | MN B 502 (-3.6A)NoneNone MN B 501 (-3.3A) | 0.72A | 1ismB-4fcxB:undetectable | 1ismB-4fcxB:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g2c | DYP2 (Amycolatopsissp. ATCC 39116) |
no annotation | 4 | HIS A 323LEU A 281ASP A 414PHE A 188 | HEM A 501 (-3.3A)NoneNoneHEM A 501 ( 4.8A) | 1.07A | 1ismB-4g2cA:undetectable | 1ismB-4g2cA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g6b | CITRATE SYNTHASE (Escherichiacoli) |
PF00285(Citrate_synt) | 4 | HIS A 226LEU A 369SER A 365ASP A 362 | None | 1.26A | 1ismB-4g6bA:undetectable | 1ismB-4g6bA:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4isy | CYSTEINE DESULFURASE (Mycobacteriumtuberculosis) |
PF00266(Aminotran_5) | 4 | HIS A 177LEU A 74SER A 71ASP A 72 | NoneNoneNoneLLP A 205 ( 4.6A) | 1.12A | 1ismB-4isyA:undetectable | 1ismB-4isyA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jx6 | PYRUVATE CARBOXYLASE (Rhizobium etli) |
PF00682(HMGL-like)PF02436(PYC_OADA) | 4 | HIS A 749LEU A 554SER A 553ASP A 549 | ZN A1102 (-3.4A)NoneNone ZN A1102 (-2.8A) | 1.21A | 1ismB-4jx6A:1.1 | 1ismB-4jx6A:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mna | LRR RECEPTOR-LIKESERINE/THREONINE-PROTEIN KINASE FLS2 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13516(LRR_6)PF13855(LRR_8) | 4 | LEU A 582SER A 581ASP A 557PHE A 563 | None | 0.81A | 1ismB-4mnaA:undetectable | 1ismB-4mnaA:17.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n78 | CYTOPLASMICFMR1-INTERACTINGPROTEIN 1 (Homo sapiens) |
PF05994(FragX_IP)PF07159(DUF1394) | 4 | TRP A 332SER A 322ASP A 275PHE A 299 | None | 1.17A | 1ismB-4n78A:undetectable | 1ismB-4n78A:12.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nky | STEROID17-ALPHA-HYDROXYLASE/17,20 LYASE (Homo sapiens) |
PF00067(p450) | 4 | LEU A 476SER A 475ASP A 487TRP A 313 | None | 1.11A | 1ismB-4nkyA:undetectable | 1ismB-4nkyA:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ook | METHIONINEAMINOPEPTIDASE 2 (Mycobacteriumtuberculosis) |
PF00557(Peptidase_M24) | 4 | LEU A 12SER A 13ASP A 75PHE A 100 | None | 1.01A | 1ismB-4ookA:undetectable | 1ismB-4ookA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qsl | PYRUVATE CARBOXYLASE (Listeriamonocytogenes) |
no annotation | 4 | HIS H 741LEU H 546SER H 545ASP H 541 | None | 1.21A | 1ismB-4qslH:undetectable | 1ismB-4qslH:12.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r3z | ARGININE--TRNALIGASE, CYTOPLASMIC (Homo sapiens) |
PF00750(tRNA-synt_1d)PF03485(Arg_tRNA_synt_N)PF05746(DALR_1) | 4 | HIS B 237SER B 387ASP B 388PHE B 337 | None | 1.04A | 1ismB-4r3zB:undetectable | 1ismB-4r3zB:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y0i | 4-AMINOBUTYRATEAMINOTRANSFERASE,MITOCHONDRIAL (Sus scrofa) |
PF00202(Aminotran_3) | 4 | HIS A 190LEU A 183SER A 184PHE A 295 | None | 1.07A | 1ismB-4y0iA:undetectable | 1ismB-4y0iA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yla | AROMATICPRENYLTRANSFERASE (Marinactinosporathermotolerans) |
PF11991(Trp_DMAT) | 4 | HIS A 258LEU A 299ASP A 249PHE A 285 | None | 1.13A | 1ismB-4ylaA:undetectable | 1ismB-4ylaA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z7g | SERINE/THREONINE-PROTEINKINASE/ENDORIBONUCLEASE IRE1 (Homo sapiens) |
PF00069(Pkinase)PF06479(Ribonuc_2-5A) | 4 | SER A 896ASP A 899TRP A 874PHE A 937 | None | 1.27A | 1ismB-4z7gA:undetectable | 1ismB-4z7gA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aee | ALPHA-GLUCOSIDASEYIHQ (Escherichiacoli) |
PF01055(Glyco_hydro_31) | 4 | HIS A 196LEU A 224ASP A 198PHE A 205 | None | 1.25A | 1ismB-5aeeA:undetectable | 1ismB-5aeeA:17.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5daj | NALD (Pseudomonasaeruginosa) |
PF00440(TetR_N)PF08361(TetR_C_2) | 4 | LEU A 76SER A 87ASP A 90PHE A 144 | None | 1.28A | 1ismB-5dajA:undetectable | 1ismB-5dajA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f75 | THIOCYANATEDEHYDROGENASE (Thioalkalivibrioparadoxus) |
no annotation | 4 | HIS A 482SER A 498ASP A 480PHE A 104 | None | 1.28A | 1ismB-5f75A:undetectable | 1ismB-5f75A:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h1o | CRISPR-ASSOCIATEDENDORIBONUCLEASECAS2 (Xanthomonasalbilineans) |
no annotation | 4 | LEU A 66SER A 65ASP A 8PHE A 39 | NoneNoneACT A 201 (-3.7A)None | 1.26A | 1ismB-5h1oA:undetectable | 1ismB-5h1oA:15.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h6s | AMIDASE (Microbacteriumsp. HM58-2) |
PF01425(Amidase) | 4 | LEU A 389SER A 149ASP A 147PHE A 391 | None | 1.10A | 1ismB-5h6sA:undetectable | 1ismB-5h6sA:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ihe | DNA POLYMERASE IISMALL SUBUNIT (Pyrococcusabyssi) |
PF00149(Metallophos) | 4 | HIS A 497SER A 359ASP A 360PHE A 463 | ZN A 703 ( 3.5A)None FE A 702 ( 3.0A)None | 1.27A | 1ismB-5iheA:undetectable | 1ismB-5iheA:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ipw | OLIGOPEPTIDE ABCTRANSPORTER,PERIPLASMICOLIGOPEPTIDE-BINDINGPROTEIN, PUTATIVE (Thermotogamaritima) |
PF00496(SBP_bac_5) | 4 | HIS A 219LEU A 262ASP A 149PHE A 224 | None | 1.22A | 1ismB-5ipwA:undetectable | 1ismB-5ipwA:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jfq | GERANYLGERANYLPYROPHOSPHATESYNTHETASE (Geoglobusacetivorans) |
PF00348(polyprenyl_synt) | 4 | LEU A 233SER A 230ASP A 217PHE A 254 | None | 1.15A | 1ismB-5jfqA:undetectable | 1ismB-5jfqA:23.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jzx | UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINEREDUCTASE (Mycobacteriumtuberculosis) |
PF01565(FAD_binding_4)PF02873(MurB_C) | 4 | LEU A 124SER A 125ASP A 107PHE A 197 | None | 0.98A | 1ismB-5jzxA:undetectable | 1ismB-5jzxA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ks8 | PYRUVATE CARBOXYLASESUBUNIT BETA (Methylobacillusflagellatus) |
PF00364(Biotin_lipoyl)PF00682(HMGL-like)PF02436(PYC_OADA) | 4 | HIS C 205LEU C 18SER C 17ASP C 13 | MN C2002 (-3.6A)NoneNone MN C2002 (-2.4A) | 1.20A | 1ismB-5ks8C:undetectable | 1ismB-5ks8C:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqi | PROTEIN TIMELESSHOMOLOG,PROTEINTIMELESS HOMOLOG (Homo sapiens) |
PF04821(TIMELESS) | 4 | TRP A 191HIS A 194LEU A 190ASP A 199 | SO4 A1602 ( 4.1A)NoneNoneNone | 1.22A | 1ismB-5mqiA:undetectable | 1ismB-5mqiA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nkz | PEROXIN 22 (Ogataea angusta) |
no annotation | 4 | LEU D 91SER D 88ASP D 86PHE D 94 | None | 1.11A | 1ismB-5nkzD:undetectable | 1ismB-5nkzD:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) |
no annotation | 4 | LEU A 60SER A 57ASP A 80PHE A 163 | NoneNoneSAH A 301 (-4.0A)None | 1.19A | 1ismB-5ufmA:undetectable | 1ismB-5ufmA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v6p | ERAD-ASSOCIATED E3UBIQUITIN-PROTEINLIGASE HRD1 (Saccharomycescerevisiae) |
no annotation | 4 | LEU A 185SER A 182ASP A 179PHE A 111 | None | 1.27A | 1ismB-5v6pA:undetectable | 1ismB-5v6pA:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vyw | PYRUVATE CARBOXYLASE (Lactococcuslactis) |
PF00289(Biotin_carb_N)PF00682(HMGL-like)PF02436(PYC_OADA)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | HIS A 734LEU A 539SER A 538ASP A 534 | MN A1201 (-4.0A)NoneNone MN A1201 (-2.8A) | 1.23A | 1ismB-5vywA:undetectable | 1ismB-5vywA:12.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wqs | BETA-AMYLASE (Ipomoea batatas) |
no annotation | 4 | HIS A 275LEU A 136ASP A 141PHE A 93 | None | 1.09A | 1ismB-5wqsA:undetectable | 1ismB-5wqsA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xmd | EPOXIDE HYDROLASE A (Vigna radiata) |
no annotation | 4 | HIS A 298LEU A 124SER A 125ASP A 263 | None | 1.23A | 1ismB-5xmdA:undetectable | 1ismB-5xmdA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xvu | CASEIN KINASE 2,ALPHA SUBUNIT (Plasmodiumfalciparum) |
PF00069(Pkinase) | 4 | HIS A 313LEU A 217SER A 216ASP A 214 | None | 1.24A | 1ismB-5xvuA:undetectable | 1ismB-5xvuA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f0x | MAD2L1-BINDINGPROTEIN (Homo sapiens) |
no annotation | 4 | LEU P 172SER P 170ASP P 168PHE P 60 | None | 1.18A | 1ismB-6f0xP:undetectable | 1ismB-6f0xP:undetectable |