SIMILAR PATTERNS OF AMINO ACIDS FOR 1ISM_A_NCAA303

	Hit	Macromolecule/ Organism	Pfam	Res.	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1ism	BONE MARROW STROMAL CELL ANTIGEN 1 (Homo sapiens)	PF02267 (Rib_hydrolayse)	9	TRP A  77 HIS A  81 LEU A  97 SER A  98 ASP A 107 TRP A 140 SER A 144 PHE A 173 GLU A 178	NCA  A 303 (-4.4A) NCA  A 303 (-4.1A) NCA  A 303 (-4.3A) NCA  A 303 (-3.9A) NCA  A 303 (-4.4A) NCA  A 303 (-4.0A) NCA  A 303 ( 3.7A) NCA  A 303 (-3.7A) NCA  A 303 ( 4.4A)	0.00A	1ismA-1ismA: 43.0	1ismA-1ismA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2eg9	ADP-RIBOSYL CYCLASE 1 (Mus musculus)	PF02267 (Rib_hydrolayse)	6	TRP A 129 LEU A 149 ASP A 159 TRP A 193 SER A 197 GLU A 230	None	0.92A	1ismA-2eg9A: 9.1	1ismA-2eg9A: 32.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2rch	CYTOCHROME P450 74A (Arabidopsis thaliana)	PF00067 (p450)	5	HIS A 342 LEU A 513 SER A 512 ASP A 496 PHE A 489	None	1.20A	1ismA-2rchA: 0.0	1ismA-2rchA: 20.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3gc6	ECTO-NAD+ GLYCOHYDROLASE (CD38 MOLECULE) (Bos taurus)	PF02267 (Rib_hydrolayse)	5	TRP A 118 LEU A 137 ASP A 147 TRP A 181 SER A 185	None	0.45A	1ismA-3gc6A: 27.4	1ismA-3gc6A: 33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3i9k	ADP-RIBOSYL CYCLASE (Aplysia californica)	PF02267 (Rib_hydrolayse)	5	TRP A  77 LEU A  97 TRP A 140 SER A 144 PHE A 174	None	0.40A	1ismA-3i9kA: 28.4	1ismA-3i9kA: 32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3p5s	CD38 MOLECULE (Bos taurus)	PF02267 (Rib_hydrolayse)	6	TRP A 118 LEU A 137 ASP A 147 TRP A 181 SER A 185 GLU A 218	AVU  A 280 (-3.8A) AVU  A 280 (-3.7A) AVU  A 280 (-3.9A) AVU  A 280 (-3.6A) AVU  A 280 (-2.9A) AVU  A 280 (-2.4A)	0.44A	1ismA-3p5sA: 27.3	1ismA-3p5sA: 33.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3rom	ADP-RIBOSYL CYCLASE 1 (Homo sapiens)	PF02267 (Rib_hydrolayse)	6	TRP A 125 LEU A 145 ASP A 155 TRP A 189 SER A 193 GLU A 226	48Z  A 301 (-3.6A) 48Z  A 301 ( 4.8A) None None 48Z  A 301 (-2.8A) 48Z  A 301 (-2.0A)	0.62A	1ismA-3romA: 28.3	1ismA-3romA: 34.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3up1	INTERLEUKIN-7 RECEPTOR SUBUNIT ALPHA (Homo sapiens)	PF00041 (fn3)	5	HIS A 160 ASP A 146 TRP A 200 SER A 203 GLU A 182	None	1.27A	1ismA-3up1A: undetectable	1ismA-3up1A: 20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4lp4	ADVANCED GLYCOSYLATION END PRODUCT-SPECIFIC RECEPTOR (Homo sapiens)	PF00047 (ig) PF08205 (C2-set_2)	5	HIS A 158 LEU A 155 SER A 209 SER A 190 GLU A 175	None	1.38A	1ismA-4lp4A: 0.0	1ismA-4lp4A: 23.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5bni	UNCHARACTERIZED PROTEIN (Sus scrofa)	PF02267 (Rib_hydrolayse)	5	LEU A 150 ASP A 160 TRP A 193 SER A 197 GLU A 230	None	0.54A	1ismA-5bniA: 26.5	1ismA-5bniA: 31.76