SIMILAR PATTERNS OF AMINO ACIDS FOR 1ICT_D_T44D129_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Salmonella
enterica) 		PF00496
(SBP_bac_5) 		4 LYS A 137
THR A 147
THR A  73
VAL A  71
 None
 0.78A 1ictD-1b2hA:
undetectable		 1ictD-1b2hA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d6v CHIMERIC GERMLINE
PRECURSOR OF
OXY-COPE CATALYTIC
ANTIBODY AZ-28
(LIGHT CHAIN)

(Homo sapiens;
Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.79A 1ictD-1d6vL:
undetectable		 1ictD-1d6vL:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g84 IMMUNOGLOBULIN E

(Homo sapiens) 		PF07654
(C1-set) 		4 LYS A  10
LEU A  12
THR A   8
LEU A  29
 None
 0.76A 1ictD-1g84A:
undetectable		 1ictD-1g84A:
22.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gke TRANSTHYRETIN

(Rattus
norvegicus) 		PF00576
(Transthyretin) 		5 LEU A  17
THR A 106
LEU A 110
THR A 119
VAL A 121
 None
 0.46A 1ictD-1gkeA:
21.9		 1ictD-1gkeA:
83.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hqs ISOCITRATE
DEHYDROGENASE

(Bacillus
subtilis) 		PF00180
(Iso_dh) 		4 THR A 305
SER A 215
THR A 217
VAL A 219
 None
 0.65A 1ictD-1hqsA:
undetectable		 1ictD-1hqsA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jg5 GTP CYCLOHYDROLASE I
FEEDBACK REGULATORY
PROTEIN

(Rattus
norvegicus) 		PF06399
(GFRP) 		4 THR A  75
SER A  68
THR A  70
VAL A  72
 None
 0.74A 1ictD-1jg5A:
undetectable		 1ictD-1jg5A:
21.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1sn2 TRANSTHYRETIN

(Sparus aurata) 		PF00576
(Transthyretin) 		5 LEU A  17
THR A 106
LEU A 110
THR A 119
VAL A 121
 None
 0.62A 1ictD-1sn2A:
20.4		 1ictD-1sn2A:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tfp TRANSTHYRETIN

(Gallus gallus) 		PF00576
(Transthyretin) 		6 LEU A  17
THR A 106
LEU A 110
SER A 117
THR A 119
VAL A 121
 None
 0.52A 1ictD-1tfpA:
19.5		 1ictD-1tfpA:
73.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1va9 DOWN SYNDROME CELL
ADHESION MOLECULE
LIKE-PROTEIN 1B

(Homo sapiens) 		PF00041
(fn3) 		4 THR A  35
SER A  31
THR A  81
VAL A  79
 None
 0.87A 1ictD-1va9A:
undetectable		 1ictD-1va9A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xhl SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY MEMBER
(5L265), PUTATIVE
TROPINONE
REDUCTASE-II

(Caenorhabditis
elegans) 		PF13561
(adh_short_C2) 		4 LEU A  90
THR A  36
SER A   8
VAL A  63
 None
 0.72A 1ictD-1xhlA:
undetectable		 1ictD-1xhlA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y8p [PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 3

(Homo sapiens) 		PF02518
(HATPase_c)
PF10436
(BCDHK_Adom3) 		4 LEU A 281
THR A 272
LEU A 276
VAL A 220
 None
 0.42A 1ictD-1y8pA:
undetectable		 1ictD-1y8pA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ydu AT5G01610

(Arabidopsis
thaliana) 		PF04398
(DUF538) 		4 LYS A 114
LEU A 112
LEU A 117
THR A 138
 None
 0.71A 1ictD-1yduA:
undetectable		 1ictD-1yduA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f17 THIAMIN
PYROPHOSPHOKINASE 1

(Mus musculus) 		PF04263
(TPK_catalytic)
PF04265
(TPK_B1_binding) 		4 LEU A 172
THR A 231
THR A 197
VAL A 195
 None
 0.80A 1ictD-2f17A:
undetectable		 1ictD-2f17A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fd5 TRANSCRIPTIONAL
REGULATOR

(Pseudomonas
aeruginosa) 		PF00440
(TetR_N) 		4 LEU A  73
LEU A  77
SER A  78
VAL A 179
 None
 0.84A 1ictD-2fd5A:
undetectable		 1ictD-2fd5A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h26 T-CELL SURFACE
GLYCOPROTEIN CD1B

(Homo sapiens) 		PF07654
(C1-set)
PF16497
(MHC_I_3) 		4 LEU A 236
THR A 248
SER A 209
VAL A 205
 GOL  A 303 ( 4.9A)
None
None
None
 0.85A 1ictD-2h26A:
undetectable		 1ictD-2h26A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ice COMPLEMENT C3 BETA
CHAIN

(Homo sapiens) 		PF01835
(A2M_N)
PF07703
(A2M_N_2) 		4 LEU A 266
THR A 246
SER A 305
THR A 307
 None
 0.63A 1ictD-2iceA:
3.8		 1ictD-2iceA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iq1 PROTEIN PHOSPHATASE
2C KAPPA, PPM1K

(Homo sapiens) 		PF00481
(PP2C) 		4 LEU A 201
THR A 191
LEU A 195
VAL A 125
 None
 0.59A 1ictD-2iq1A:
undetectable		 1ictD-2iq1A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ivf ETHYLBENZENE
DEHYDROGENASE
ALPHA-SUBUNIT

(Aromatoleum
aromaticum) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		4 LEU A 606
THR A 857
LEU A 635
THR A 637
 None
MD1  A1987 ( 4.1A)
None
MD1  A1987 (-3.5A)
 0.85A 1ictD-2ivfA:
undetectable		 1ictD-2ivfA:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o8x PROBABLE RNA
POLYMERASE SIGMA-C
FACTOR

(Mycobacterium
tuberculosis) 		PF08281
(Sigma70_r4_2) 		4 LEU A 141
THR A 162
LEU A 147
SER A 148
 None
SO4  A 108 (-3.7A)
None
None
 0.60A 1ictD-2o8xA:
undetectable		 1ictD-2o8xA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pfc HYPOTHETICAL PROTEIN
RV0098/MT0107

(Mycobacterium
tuberculosis) 		PF10862
(FcoT) 		4 LEU A 141
LEU A  54
SER A  47
THR A  49
 None
 0.47A 1ictD-2pfcA:
undetectable		 1ictD-2pfcA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qv3 VACUOLATING
CYTOTOXIN

(Helicobacter
pylori) 		PF02691
(VacA) 		4 THR A 641
LEU A 645
SER A 624
VAL A 620
 None
 0.82A 1ictD-2qv3A:
undetectable		 1ictD-2qv3A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2tbv TOMATO BUSHY STUNT
VIRUS

(Tomato bushy
stunt virus) 		PF00729
(Viral_coat) 		4 LEU A 132
THR A 243
LEU A 239
VAL A 176
 None
 0.83A 1ictD-2tbvA:
undetectable		 1ictD-2tbvA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xtl CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae) 		PF16569
(GramPos_pilinBB)
PF16570
(GramPos_pilinD3) 		4 LYS A 400
THR A 352
THR A 434
VAL A 432
 None
 0.84A 1ictD-2xtlA:
5.9		 1ictD-2xtlA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z23 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Yersinia pestis) 		PF00496
(SBP_bac_5) 		4 LYS A 137
THR A 147
THR A  73
VAL A  71
 None
 0.70A 1ictD-2z23A:
undetectable		 1ictD-2z23A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3blw ISOCITRATE
DEHYDROGENASE [NAD]
SUBUNIT 1

(Saccharomyces
cerevisiae) 		PF00180
(Iso_dh) 		4 THR A 235
SER A 177
THR A 179
VAL A 181
 None
 0.82A 1ictD-3blwA:
undetectable		 1ictD-3blwA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dms ISOCITRATE
DEHYDROGENASE [NADP]

(Burkholderia
pseudomallei) 		PF00180
(Iso_dh) 		4 THR A 303
SER A 226
THR A 228
VAL A 230
 None
 0.68A 1ictD-3dmsA:
undetectable		 1ictD-3dmsA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3exh PYRUVATE
DEHYDROGENASE E1
COMPONENT SUBUNIT
BETA, MITOCHONDRIAL

(Homo sapiens) 		PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 LEU B 288
THR B 261
THR B 208
VAL B 210
 None
 0.67A 1ictD-3exhB:
undetectable		 1ictD-3exhB:
16.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3fc8 TRANSTHYRETIN

(Homo sapiens) 		PF00576
(Transthyretin) 		5 LEU A  17
THR A 106
LEU A 110
THR A 119
VAL A 121
 IFA  A3000 ( 4.7A)
IFA  A3000 (-4.9A)
IFA  A3000 (-4.1A)
IFA  A3000 ( 4.9A)
None
 0.49A 1ictD-3fc8A:
22.7		 1ictD-3fc8A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ge2 LIPOPROTEIN,
PUTATIVE

(Streptococcus
pneumoniae) 		PF12182
(DUF3642) 		4 THR A  96
LEU A 100
THR A  87
VAL A  89
 None
 0.47A 1ictD-3ge2A:
undetectable		 1ictD-3ge2A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hjr EXTRACELLULAR SERINE
PROTEASE

(Aeromonas
sobria) 		PF00082
(Peptidase_S8)
PF01483
(P_proprotein) 		4 LEU A 493
LEU A 549
SER A 462
THR A 464
 None
 0.76A 1ictD-3hjrA:
undetectable		 1ictD-3hjrA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i44 ALDEHYDE
DEHYDROGENASE

(Bartonella
henselae) 		PF00171
(Aldedh) 		4 LEU A 173
LEU A 146
SER A 224
THR A 226
 None
 0.72A 1ictD-3i44A:
undetectable		 1ictD-3i44A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iwk AMINOALDEHYDE
DEHYDROGENASE

(Pisum sativum) 		PF00171
(Aldedh) 		4 LEU A 184
LEU A 157
SER A 235
THR A 237
 None
 0.84A 1ictD-3iwkA:
undetectable		 1ictD-3iwkA:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kd4 PUTATIVE PROTEASE

(Parabacteroides
distasonis) 		PF12969
(DUF3857)
PF12970
(DUF3858) 		4 LYS A 394
THR A 449
THR A 492
VAL A 490
 None
 0.85A 1ictD-3kd4A:
undetectable		 1ictD-3kd4A:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m49 TRANSKETOLASE

(Bacillus
anthracis) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 THR A 108
LEU A  79
SER A  80
VAL A 111
 None
 0.74A 1ictD-3m49A:
undetectable		 1ictD-3m49A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m8u HEME-BINDING PROTEIN
A

(Glaesserella
parasuis) 		PF00496
(SBP_bac_5) 		4 LYS A 160
THR A  86
SER A  77
THR A  79
 None
 0.66A 1ictD-3m8uA:
undetectable		 1ictD-3m8uA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nps S4 FAB LIGHT CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU C 135
THR C 172
SER C 162
THR C 164
 None
 0.71A 1ictD-3npsC:
undetectable		 1ictD-3npsC:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o4r DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4

(Homo sapiens) 		PF13561
(adh_short_C2) 		4 LEU A 223
THR A 274
SER A 232
THR A 236
 None
 0.85A 1ictD-3o4rA:
undetectable		 1ictD-3o4rA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3prx COBRA VENOM FACTOR

(Naja kaouthia) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		4 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.60A 1ictD-3prxB:
2.0		 1ictD-3prxB:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rpi LIGHT CHAIN FROM
HIGHLY POTENT
ANTI-HIV
NEUTRALIZING
ANTIBODY

(Homo sapiens) 		no annotation 4 LEU L 124
THR L 161
SER L 151
THR L 153
 None
 0.79A 1ictD-3rpiL:
undetectable		 1ictD-3rpiL:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ru8 ANTIBODY B12, LIGHT
CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 136
THR L 173
SER L 163
THR L 165
 None
None
GOL  L 217 ( 3.7A)
None
 0.71A 1ictD-3ru8L:
3.9		 1ictD-3ru8L:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s4y THIAMIN
PYROPHOSPHOKINASE 1

(Homo sapiens) 		PF04263
(TPK_catalytic)
PF04265
(TPK_B1_binding) 		4 LEU A 172
THR A 231
THR A 197
VAL A 195
 None
 0.84A 1ictD-3s4yA:
undetectable		 1ictD-3s4yA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tch PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Escherichia
coli) 		PF00496
(SBP_bac_5) 		4 LYS A 163
THR A 173
THR A  99
VAL A  97
 None
 0.82A 1ictD-3tchA:
undetectable		 1ictD-3tchA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3txa CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae) 		PF00092
(VWA) 		4 LYS A 189
THR A 206
THR A 674
VAL A 672
 None
 0.65A 1ictD-3txaA:
undetectable		 1ictD-3txaA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ty7 PUTATIVE ALDEHYDE
DEHYDROGENASE
SAV2122

(Staphylococcus
aureus) 		PF00171
(Aldedh) 		4 LEU A 169
LEU A 142
SER A 220
THR A 222
 None
 0.75A 1ictD-3ty7A:
undetectable		 1ictD-3ty7A:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u4b CH02 LIGHT CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.75A 1ictD-3u4bL:
3.8		 1ictD-3u4bL:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190

(Saccharomyces
cerevisiae) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 LEU A 125
THR A1605
SER A 207
THR A 209
 None
 0.81A 1ictD-4c3hA:
undetectable		 1ictD-4c3hA:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g6j LIGHT CHAIN OF
ANTIBODY BINDING
FRAGMENT OF
CANAKINUMAB

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.72A 1ictD-4g6jL:
undetectable		 1ictD-4g6jL:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gl8 OLIGOPEPTIDE ABC
TRANSPORTER OPPAIV

(Borreliella
burgdorferi) 		PF00496
(SBP_bac_5) 		4 LYS A 156
THR A 166
THR A  93
VAL A  91
 None
 0.76A 1ictD-4gl8A:
undetectable		 1ictD-4gl8A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hjj ANTI-IL12 ANTI-IL18
DFAB LIGHT CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 249
THR L 286
SER L 276
THR L 278
 None
None
GOL  L 401 (-3.3A)
None
 0.74A 1ictD-4hjjL:
undetectable		 1ictD-4hjjL:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ht1 CHIMERIC ANTIBODY
FAB

(Oryctolagus
cuniculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 139
THR L 176
SER L 166
THR L 168
 None
 0.66A 1ictD-4ht1L:
undetectable		 1ictD-4ht1L:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i3r LIGHT CHAIN OF
VRC-PG04 FAB

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.82A 1ictD-4i3rL:
2.6		 1ictD-4i3rL:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE

(Solanum
lycopersicum) 		PF00171
(Aldedh) 		4 LEU A 184
LEU A 157
SER A 235
THR A 237
 None
None
None
NAD  A 601 (-4.2A)
 0.81A 1ictD-4i8qA:
undetectable		 1ictD-4i8qA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iml CROSSED HEAVY CHAIN
(VH-CKAPPA)

(Homo sapiens) 		no annotation 4 LEU H 157
THR H 194
SER H 184
THR H 186
 None
 0.82A 1ictD-4imlH:
undetectable		 1ictD-4imlH:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j6r LIGHT CHAIN OF
ANTIBODY VRC23

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.72A 1ictD-4j6rL:
3.0		 1ictD-4j6rL:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jfz FAB LIGHT CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.78A 1ictD-4jfzL:
4.0		 1ictD-4jfzL:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jm4 PGT 135 LIGHT CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.75A 1ictD-4jm4L:
undetectable		 1ictD-4jm4L:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jpw LIGHT CHAIN OF
ANTIBODY 12A21

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.78A 1ictD-4jpwL:
3.4		 1ictD-4jpwL:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jzn ANTI-HCV E2 FAB
HC84-1 LIGHT CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU B 134
THR B 171
SER B 161
THR B 163
 None
 0.81A 1ictD-4jznB:
undetectable		 1ictD-4jznB:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4krp CETUXIMAB LIGHT
CHAIN

(Homo sapiens;
Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU C 135
THR C 172
SER C 162
THR C 164
 None
 0.67A 1ictD-4krpC:
undetectable		 1ictD-4krpC:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l1y SALIVARY NITROPHORIN

(Cimex
lectularius) 		no annotation 4 LEU A  86
SER A  13
THR A  11
VAL A   9
 None
 0.76A 1ictD-4l1yA:
undetectable		 1ictD-4l1yA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lsq LIGHT CHAIN OF
ANTIBODY VRC-CH31
WITH N70D MUTATION

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.79A 1ictD-4lsqL:
undetectable		 1ictD-4lsqL:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ma3 C2095 LIGHT CHAIN

(Homo sapiens;
Oryctolagus
cuniculus) 		no annotation 4 LEU L 141
THR L 178
SER L 168
THR L 170
 None
 0.72A 1ictD-4ma3L:
undetectable		 1ictD-4ma3L:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mfi SN-GLYCEROL-3-PHOSPH
ATE ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN USPB

(Mycobacterium
tuberculosis) 		PF13416
(SBP_bac_8) 		4 LEU A 117
THR A 331
LEU A 120
VAL A 330
 None
 0.87A 1ictD-4mfiA:
undetectable		 1ictD-4mfiA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mio INOSITOL
2-DEHYDROGENASE/D-CH
IRO-INOSITOL
3-DEHYDROGENASE

(Lactobacillus
casei) 		PF01408
(GFO_IDH_MocA) 		4 LEU A 213
LEU A 227
SER A 154
VAL A 150
 None
None
GOL  A 402 (-2.8A)
None
 0.84A 1ictD-4mioA:
undetectable		 1ictD-4mioA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mna LRR RECEPTOR-LIKE
SERINE/THREONINE-PRO
TEIN KINASE FLS2

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 LEU A 395
SER A 373
THR A 349
VAL A 325
 None
 0.86A 1ictD-4mnaA:
undetectable		 1ictD-4mnaA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE

(Campylobacter
jejuni) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		4 LEU A 101
THR A   8
LEU A  45
VAL A 334
 None
 0.86A 1ictD-4n3oA:
undetectable		 1ictD-4n3oA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nec PUTATIVE
SAM-DEPENDENT
METHYLTRANSFERASE

(Streptomyces
lasaliensis) 		PF13649
(Methyltransf_25) 		4 LEU A 218
THR A 107
LEU A 142
SER A 111
 None
None
None
SAH  A 401 (-3.3A)
 0.78A 1ictD-4necA:
undetectable		 1ictD-4necA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ono BETA-2-MICROGLOBULIN
/T-CELL SURFACE
GLYCOPROTEIN
CD1C/T-CELL SURFACE
GLYCOPROTEIN CD1B
CHIMERIC PROTEIN

(Homo sapiens) 		PF07654
(C1-set)
PF16497
(MHC_I_3) 		4 LEU A 352
THR A 364
SER A 325
VAL A 321
 None
 0.83A 1ictD-4onoA:
undetectable		 1ictD-4onoA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p0e MAF-LIKE PROTEIN
YHDE

(Escherichia
coli) 		PF02545
(Maf) 		4 LEU A  67
THR A 105
LEU A 109
VAL A 120
 None
 0.60A 1ictD-4p0eA:
undetectable		 1ictD-4p0eA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4phb UNCHARACTERIZED
PROTEIN

(Ruminiclostridium
thermocellum) 		PF14262
(Cthe_2159) 		4 LYS A 189
THR A 164
THR A 130
VAL A 128
 None
 0.69A 1ictD-4phbA:
undetectable		 1ictD-4phbA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qti UROKINASE
PLASMINOGEN
ACTIVATOR SURFACE
RECEPTOR

(Homo sapiens) 		PF00021
(UPAR_LY6) 		4 THR U  26
SER U  65
THR U  67
VAL U  69
 None
 0.58A 1ictD-4qtiU:
undetectable		 1ictD-4qtiU:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rjk ACETOLACTATE
SYNTHASE

(Bacillus
subtilis) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 LEU A 325
THR A 304
LEU A 308
VAL A 281
 None
 0.73A 1ictD-4rjkA:
undetectable		 1ictD-4rjkA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rx4 8ANC134 LIGHT CHAIN

(Homo sapiens) 		no annotation 4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.67A 1ictD-4rx4L:
2.8		 1ictD-4rx4L:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wo4 ANTIGEN-PRESENTING
GLYCOPROTEIN CD1D

(Homo sapiens) 		PF07654
(C1-set)
PF16497
(MHC_I_3) 		4 LEU A 236
THR A 248
SER A 209
VAL A 205
 None
 0.81A 1ictD-4wo4A:
undetectable		 1ictD-4wo4A:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xny LIGHT CHAIN OF
ANTIBODY VRC08C

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.68A 1ictD-4xnyL:
undetectable		 1ictD-4xnyL:
25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ydi LIGHT CHAIN OF
ANTIBODY
Z258-VRC27.01

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.68A 1ictD-4ydiL:
undetectable		 1ictD-4ydiL:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ydl LIGHT CHAIN OF
ANTIBODY
C38-VRC18.02

(Homo sapiens) 		no annotation 4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.67A 1ictD-4ydlL:
undetectable		 1ictD-4ydlL:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ye4 LIGHT CHAIN OF HJ16

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 142
THR L 179
SER L 169
THR L 171
 None
 0.72A 1ictD-4ye4L:
undetectable		 1ictD-4ye4L:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ado FAB A.17

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 137
THR L 174
SER L 164
THR L 166
 None
 0.77A 1ictD-5adoL:
undetectable		 1ictD-5adoL:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5al7 SPINDLE ASSEMBLY
ABNORMAL PROTEIN 6
HOMOLOG

(Drosophila
melanogaster) 		PF16531
(SAS-6_N) 		4 LEU A  47
LEU A  62
THR A  74
VAL A  76
 None
 0.55A 1ictD-5al7A:
undetectable		 1ictD-5al7A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c9j T-CELL SURFACE
GLYCOPROTEIN
CD1C,T-CELL SURFACE
GLYCOPROTEIN CD1B

(Homo sapiens) 		PF07654
(C1-set)
PF16497
(MHC_I_3) 		4 LEU A 240
THR A 252
SER A 213
VAL A 209
 None
 0.82A 1ictD-5c9jA:
undetectable		 1ictD-5c9jA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cma ANTIBODY CH8H9 FAB
LIGHT CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU A 135
THR A 172
SER A 162
THR A 164
 None
 0.75A 1ictD-5cmaA:
3.7		 1ictD-5cmaA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cyb LIPOPROTEIN

(Streptococcus
pneumoniae) 		PF12182
(DUF3642) 		4 THR A  95
LEU A  99
THR A  86
VAL A  88
 None
 0.43A 1ictD-5cybA:
undetectable		 1ictD-5cybA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dd5 ANTI-HIV ANTIBODY
DH570.9 FAB HEAVY
CHAIN

(Macaca mulatta) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.68A 1ictD-5dd5L:
3.8		 1ictD-5dd5L:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5drz HIV ANTIBODY F240
LIGHT CHAIN

(Homo sapiens) 		no annotation 4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.82A 1ictD-5drzL:
undetectable		 1ictD-5drzL:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fgc ANTI-HCV E2 FAB
HC33.8 LIGHT CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU B 135
THR B 172
SER B 162
THR B 164
 None
 0.75A 1ictD-5fgcB:
undetectable		 1ictD-5fgcB:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h5v FLAGELLAR
HOOK-ASSOCIATED
PROTEIN 2

(Escherichia
coli) 		PF02465
(FliD_N)
PF07195
(FliD_C) 		4 LYS A  94
THR A 261
SER A  74
THR A  76
 None
 0.71A 1ictD-5h5vA:
undetectable		 1ictD-5h5vA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hz1 PROBABLE LRR
RECEPTOR-LIKE
SERINE/THREONINE-PRO
TEIN KINASE
AT4G26540

(Arabidopsis
thaliana) 		PF13855
(LRR_8) 		4 LEU B 369
SER B 347
THR B 323
VAL B 299
 None
 0.83A 1ictD-5hz1B:
undetectable		 1ictD-5hz1B:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i8k HHH1 FAB LIGHT CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 138
THR L 175
SER L 165
THR L 167
 None
 0.73A 1ictD-5i8kL:
undetectable		 1ictD-5i8kL:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i8o HMM5 ANTIBODY LIGHT
CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 138
THR L 175
SER L 165
THR L 167
 None
 0.77A 1ictD-5i8oL:
undetectable		 1ictD-5i8oL:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jmc SYNAPTIC VESICLE
GLYCOPROTEIN 2C

(Rattus
norvegicus) 		PF13599
(Pentapeptide_4) 		4 LYS B 533
THR B 511
THR B 493
VAL B 491
 None
 0.60A 1ictD-5jmcB:
undetectable		 1ictD-5jmcB:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5koh NITROGENASE FEMO
BETA SUBUNIT PROTEIN
NIFK

(Gluconacetobacter
diazotrophicus) 		PF00148
(Oxidored_nitro)
PF11844
(DUF3364) 		4 LEU B 454
THR B 484
LEU B 437
VAL B 481
 None
 0.83A 1ictD-5kohB:
undetectable		 1ictD-5kohB:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo sapiens) 		no annotation 4 LEU B 147
THR B 124
LEU B 128
THR B 119
 None
 0.67A 1ictD-5ofbB:
undetectable		 1ictD-5ofbB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5te6 LIGHT CHAIN OF N6

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.69A 1ictD-5te6L:
3.3		 1ictD-5te6L:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u0l N-SUCCINYLGLUTAMATE
5-SEMIALDEHYDE
DEHYDROGENASE

(Marinobacter
hydrocarbonoclasticus) 		PF00171
(Aldedh) 		4 THR A 386
LEU A 363
SER A 364
VAL A 368
 EDO  A 505 ( 3.9A)
None
None
None
 0.65A 1ictD-5u0lA:
undetectable		 1ictD-5u0lA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u3k DH511.2 FAB LIGHT
CHAIN

(Homo sapiens) 		no annotation 4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.71A 1ictD-5u3kL:
undetectable		 1ictD-5u3kL:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u3n DH511.12P FAB LIGHT
CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.77A 1ictD-5u3nL:
undetectable		 1ictD-5u3nL:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u3p DH511.4 FAB LIGHT
CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.69A 1ictD-5u3pL:
undetectable		 1ictD-5u3pL:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bja ACETYL-COA
ACETYLTRANSFERASE A

(Ascaris suum) 		no annotation 4 THR A  87
SER A  83
THR A  55
VAL A  57
 None
 0.72A 1ictD-6bjaA:
undetectable		 1ictD-6bjaA:
27.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fb3 TENEURIN-2

(Gallus gallus) 		no annotation 4 THR A1773
SER A1784
THR A1786
VAL A1788
 None
 0.44A 1ictD-6fb3A:
undetectable		 1ictD-6fb3A:
22.69