SIMILAR PATTERNS OF AMINO ACIDS FOR 1ICT_D_T44D129_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a1s | ORNITHINECARBAMOYLTRANSFERASE (Pyrococcusfuriosus) |
PF00185(OTCace)PF02729(OTCace_N) | 4 | LEU A 139ALA A 303LEU A 24THR A 26 | None | 1.05A | 1ictB-1a1sA:undetectable | 1ictB-1a1sA:15.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bbj | IGG4-KAPPA B72.3 FAB(HEAVY CHAIN)IGG4-KAPPA B72.3 FAB(LIGHT CHAIN) (Homo sapiens;Mus musculus) |
no annotation | 4 | LEU L 135ALA H 138SER H 133THR H 136 | None | 0.98A | 1ictB-1bbjL:3.9 | 1ictB-1bbjL:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e6b | GLUTATHIONES-TRANSFERASE (Arabidopsisthaliana) |
PF13409(GST_N_2)PF14497(GST_C_3) | 4 | LEU A 147ALA A 159LEU A 150THR A 160 | NoneNoneNoneBME A 389 ( 4.9A) | 1.04A | 1ictB-1e6bA:undetectable | 1ictB-1e6bA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eb3 | 5-AMINOLAEVULINICACID DEHYDRATASE (Saccharomycescerevisiae) |
PF00490(ALAD) | 4 | LYS A 81LEU A 78ALA A 80LEU A 75 | None | 1.07A | 1ictB-1eb3A:undetectable | 1ictB-1eb3A:14.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f80 | HOLO-(ACYL CARRIERPROTEIN) SYNTHASE (Bacillussubtilis) |
PF01648(ACPS) | 4 | LEU A 7ALA A 111SER A 102THR A 104 | NoneNoneNone NA A1255 (-3.8A) | 0.72A | 1ictB-1f80A:undetectable | 1ictB-1f80A:24.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g0d | PROTEIN-GLUTAMINEGAMMA-GLUTAMYLTRANSFERASE (Pagrus major) |
PF00868(Transglut_N)PF00927(Transglut_C)PF01841(Transglut_core) | 4 | LEU A 506ALA A 563LEU A 565THR A 576 | None | 0.70A | 1ictB-1g0dA:0.1 | 1ictB-1g0dA:14.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1gke | TRANSTHYRETIN (Rattusnorvegicus) |
PF00576(Transthyretin) | 6 | LYS A 15LEU A 17ALA A 108LEU A 110SER A 117THR A 119 | None | 0.64A | 1ictB-1gkeA:21.8 | 1ictB-1gkeA:83.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gut | MOLYBDATE BINDINGPROTEIN II (Clostridiumpasteurianum) |
PF03459(TOBE) | 4 | LYS A 18LEU A 16ALA A 23SER A 37 | None | 0.86A | 1ictB-1gutA:undetectable | 1ictB-1gutA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hju | BETA-1,4-GALACTANASE (Thermothelomycesthermophila) |
PF07745(Glyco_hydro_53) | 5 | LEU A 120ALA A 116LEU A 169SER A 167THR A 113 | None | 1.23A | 1ictB-1hjuA:undetectable | 1ictB-1hjuA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i36 | CONSERVEDHYPOTHETICAL PROTEINMTH1747 (Methanothermobacterthermautotrophicus) |
PF03807(F420_oxidored)PF09130(DUF1932) | 4 | LEU A 183ALA A 179LEU A 185THR A 176 | None | 1.07A | 1ictB-1i36A:undetectable | 1ictB-1i36A:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1izm | HYPOTHETICAL PROTEINHI0817 (Haemophilusinfluenzae) |
PF03695(UPF0149) | 4 | LEU A 42ALA A 54LEU A 45SER A 49 | None | 1.01A | 1ictB-1izmA:undetectable | 1ictB-1izmA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j0a | 1-AMINOCYCLOPROPANE-1-CARBOXYLATEDEAMINASE (Pyrococcushorikoshii) |
PF00291(PALP) | 4 | LEU A 94ALA A 90LEU A 96THR A 87 | None | 0.93A | 1ictB-1j0aA:undetectable | 1ictB-1j0aA:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jmy | BILE-SALT-ACTIVATEDLIPASE (Homo sapiens) |
PF00135(COesterase) | 4 | LYS A 361LEU A 357ALA A 360THR A 352 | None | 1.07A | 1ictB-1jmyA:undetectable | 1ictB-1jmyA:12.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k25 | LOW-AFFINITYPENICILLIN-BINDINGPROTEIN 2X (Streptococcuspneumoniae) |
PF00905(Transpeptidase)PF03717(PBP_dimer)PF03793(PASTA) | 4 | LEU A 585ALA A 291LEU A 293THR A 305 | None | 0.84A | 1ictB-1k25A:undetectable | 1ictB-1k25A:10.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1miu | BREAST CANCER TYPE 2SUSCEPTIBILITYPROTEIN (Mus musculus) |
PF09103(BRCA-2_OB1)PF09104(BRCA-2_OB3)PF09121(Tower)PF09169(BRCA-2_helical) | 4 | LEU A2906ALA A2948LEU A2946SER A2933 | None | 1.04A | 1ictB-1miuA:undetectable | 1ictB-1miuA:10.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sb3 | 4-HYDROXYBENZOYL-COAREDUCTASE BETASUBUNIT (Thaueraaromatica) |
PF00941(FAD_binding_5)PF03450(CO_deh_flav_C) | 4 | LEU B 252ALA B 240LEU B 242SER B 219 | None | 0.81A | 1ictB-1sb3B:undetectable | 1ictB-1sb3B:16.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1sn2 | TRANSTHYRETIN (Sparus aurata) |
PF00576(Transthyretin) | 4 | LEU A 17ALA A 108LEU A 110THR A 119 | None | 0.45A | 1ictB-1sn2A:20.4 | 1ictB-1sn2A:54.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1sn2 | TRANSTHYRETIN (Sparus aurata) |
PF00576(Transthyretin) | 4 | LYS A 15LEU A 17LEU A 110THR A 119 | None | 0.76A | 1ictB-1sn2A:20.4 | 1ictB-1sn2A:54.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sqg | SUN PROTEIN (Escherichiacoli) |
PF01029(NusB)PF01189(Methyltr_RsmB-F) | 5 | LEU A 352ALA A 323LEU A 349SER A 326THR A 374 | None | 1.45A | 1ictB-1sqgA:undetectable | 1ictB-1sqgA:14.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t4n | RIBONUCLEASE III (Saccharomycescerevisiae) |
PF00035(dsrm) | 4 | LYS A 443ALA A 446LEU A 377SER A 376 | None | 0.99A | 1ictB-1t4nA:undetectable | 1ictB-1t4nA:22.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tfp | TRANSTHYRETIN (Gallus gallus) |
PF00576(Transthyretin) | 5 | LYS A 15LEU A 17ALA A 108LEU A 110SER A 117 | None | 0.78A | 1ictB-1tfpA:19.2 | 1ictB-1tfpA:73.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tfp | TRANSTHYRETIN (Gallus gallus) |
PF00576(Transthyretin) | 5 | LYS A 15LEU A 17ALA A 108LEU A 110THR A 119 | None | 0.77A | 1ictB-1tfpA:19.2 | 1ictB-1tfpA:73.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tvz | 3-HYDROXY-3-METHYLGLUTARYL-COA SYNTHASE (Staphylococcusaureus) |
PF01154(HMG_CoA_synt_N)PF08540(HMG_CoA_synt_C) | 4 | LYS A 2ALA A 170SER A 315THR A 317 | None | 0.81A | 1ictB-1tvzA:undetectable | 1ictB-1tvzA:15.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uun | MSPA (Mycolicibacteriumsmegmatis) |
PF09203(MspA) | 4 | LEU A 62ALA A 164LEU A 166THR A 176 | None | 0.63A | 1ictB-1uunA:undetectable | 1ictB-1uunA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wnb | PUTATIVE BETAINEALDEHYDEDEHYDROGENASE (Escherichiacoli) |
PF00171(Aldedh) | 4 | LEU A 171ALA A 146SER A 221THR A 223 | NoneNoneNoneNAI A1001 (-4.5A) | 0.99A | 1ictB-1wnbA:undetectable | 1ictB-1wnbA:14.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xg2 | PECTINESTERASE 1 (Solanumlycopersicum) |
PF01095(Pectinesterase) | 4 | LYS A 107ALA A 103LEU A 71THR A 102 | None | 1.07A | 1ictB-1xg2A:undetectable | 1ictB-1xg2A:17.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yht | DSPB (Aggregatibacteractinomycetemcomitans) |
PF00728(Glyco_hydro_20) | 4 | LEU A 277ALA A 325LEU A 327THR A 19 | None | 0.86A | 1ictB-1yhtA:undetectable | 1ictB-1yhtA:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yr2 | PROLYLOLIGOPEPTIDASE (Novosphingobiumcapsulatum) |
PF00326(Peptidase_S9)PF02897(Peptidase_S9_N) | 4 | LEU A 684ALA A 649LEU A 651SER A 596 | None | 0.81A | 1ictB-1yr2A:undetectable | 1ictB-1yr2A:11.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b9l | PROPHENOLOXIDASEACTIVATING FACTOR (Holotrichiadiomphalia) |
PF00089(Trypsin) | 4 | ALA A 191LEU A 196SER A 188THR A 270 | None | 0.93A | 1ictB-2b9lA:undetectable | 1ictB-2b9lA:15.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bk9 | CG9734-PA (Drosophilamelanogaster) |
PF00042(Globin) | 4 | LEU A 114ALA A 128LEU A 117SER A 121 | None | 1.03A | 1ictB-2bk9A:undetectable | 1ictB-2bk9A:23.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bod | ENDOGLUCANASE E-2 (Thermobifidafusca) |
PF01341(Glyco_hydro_6) | 4 | LYS X 202ALA X 201SER X 160THR X 186 | None | 1.07A | 1ictB-2bodX:undetectable | 1ictB-2bodX:16.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c2i | RV0130 (Mycobacteriumtuberculosis) |
PF01575(MaoC_dehydratas) | 4 | LEU A 70LEU A 73SER A 21THR A 109 | None | 1.04A | 1ictB-2c2iA:undetectable | 1ictB-2c2iA:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cs3 | PROTEIN C14ORF4 (Homo sapiens) |
PF00097(zf-C3HC4) | 4 | LYS A 51LEU A 87ALA A 55THR A 56 | None | 1.07A | 1ictB-2cs3A:undetectable | 1ictB-2cs3A:25.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ism | PUTATIVEOXIDOREDUCTASE (Thermusthermophilus) |
PF07995(GSDH) | 4 | LEU A 45ALA A 65LEU A 55SER A 62 | None | 1.05A | 1ictB-2ismA:undetectable | 1ictB-2ismA:16.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kc3 | APOLIPOPROTEIN E (Homo sapiens) |
PF01442(Apolipoprotein) | 4 | LEU A 78ALA A 164SER A 22THR A 18 | None | 1.06A | 1ictB-2kc3A:undetectable | 1ictB-2kc3A:16.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o3j | UDP-GLUCOSE6-DEHYDROGENASE (Caenorhabditiselegans) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 4 | LEU A 291ALA A 304LEU A 294SER A 297 | None | 1.07A | 1ictB-2o3jA:undetectable | 1ictB-2o3jA:14.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pjd | RIBOSOMAL RNA SMALLSUBUNITMETHYLTRANSFERASE C (Escherichiacoli) |
PF05175(MTS)PF08468(MTS_N) | 4 | LEU A 11ALA A 7LEU A 12THR A 5 | None | 1.08A | 1ictB-2pjdA:undetectable | 1ictB-2pjdA:16.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pv7 | T-PROTEIN [INCLUDES:CHORISMATE MUTASE(EC 5.4.99.5) (CM)AND PREPHENATEDEHYDROGENASE (EC1.3.1.12) (PDH)] (Haemophilusinfluenzae) |
PF02153(PDH) | 4 | LEU A 199ALA A 175LEU A 177SER A 151 | NoneNoneNoneNAD A 400 (-3.8A) | 1.05A | 1ictB-2pv7A:undetectable | 1ictB-2pv7A:19.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pvz | PRPF METHYLACONITATEISOMERASE (Shewanellaoneidensis) |
PF04303(PrpF) | 4 | LYS A 59ALA A 67SER A 69THR A 71 | CA A1002 (-3.3A)None CA A1003 (-3.3A)None | 1.04A | 1ictB-2pvzA:undetectable | 1ictB-2pvzA:16.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v9u | MSPA (Mycolicibacteriumsmegmatis) |
PF09203(MspA) | 4 | LEU A 62ALA A 164LEU A 166THR A 176 | LEU A 62 ( 0.5A)ALA A 164 ( 0.0A)LEU A 166 ( 0.5A)THR A 176 ( 0.8A) | 0.55A | 1ictB-2v9uA:3.2 | 1ictB-2v9uA:23.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vjt | ALLOPHYCOCYANINALPHA SUBUNITALLOPHYCOCYANIN BETASUBUNIT (Gloeobacterviolaceus) |
PF00502(Phycobilisome) | 4 | LEU B 97ALA A 7LEU A 4SER A 2 | None | 1.02A | 1ictB-2vjtB:undetectable | 1ictB-2vjtB:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w6d | DYNAMIN FAMILYPROTEIN (Nostocpunctiforme) |
PF00350(Dynamin_N) | 4 | LEU A 49ALA A 38LEU A 51THR A 34 | None | 0.80A | 1ictB-2w6dA:undetectable | 1ictB-2w6dA:12.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y0e | UDP-GLUCOSEDEHYDROGENASE (Burkholderiacepacia) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 4 | LEU A 278ALA A 219SER A 296THR A 223 | None | 1.06A | 1ictB-2y0eA:undetectable | 1ictB-2y0eA:13.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yu1 | JMJCDOMAIN-CONTAININGHISTONEDEMETHYLATIONPROTEIN 1A (Homo sapiens) |
PF02373(JmjC) | 4 | LEU A 496LEU A 499SER A 502THR A 454 | None | 1.07A | 1ictB-2yu1A:undetectable | 1ictB-2yu1A:13.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z2m | PENICILLIN-BINDINGPROTEIN 2X (Streptococcuspneumoniae) |
PF00905(Transpeptidase) | 4 | LEU B 585ALA B 291LEU B 293THR B 305 | None | 0.88A | 1ictB-2z2mB:undetectable | 1ictB-2z2mB:17.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zch | MONOCLONAL ANTIBODY8G8F5 FAB (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 4 | LYS H 205ALA H 198SER H 149THR H 151 | None | 0.76A | 1ictB-2zchH:undetectable | 1ictB-2zchH:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b8k | DIHYDROLIPOYLLYSINE-RESIDUEACETYLTRANSFERASE (Homo sapiens) |
PF00198(2-oxoacid_dh) | 4 | LEU A 482ALA A 503SER A 527THR A 529 | None | 0.58A | 1ictB-3b8kA:undetectable | 1ictB-3b8kA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bdw | NKG2-A/NKG2-B TYPEII INTEGRAL MEMBRANEPROTEIN (Homo sapiens) |
PF00059(Lectin_C) | 4 | LEU B 216ALA B 209LEU B 211SER B 173 | None | 0.95A | 1ictB-3bdwB:undetectable | 1ictB-3bdwB:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d1r | FRUCTOSE-1,6-BISPHOSPHATASE CLASS IIGLPX (Escherichiacoli) |
PF03320(FBPase_glpX) | 4 | ALA A 102LEU A 104SER A 281THR A 283 | None | 0.78A | 1ictB-3d1rA:undetectable | 1ictB-3d1rA:16.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3daf | 5,10-METHENYLTETRAHYDROMETHANOPTERINHYDROGENASE (Methanocaldococcusjannaschii) |
PF03201(HMD) | 4 | LEU A 337ALA A 318LEU A 315THR A 317 | None | 1.08A | 1ictB-3dafA:undetectable | 1ictB-3dafA:15.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3duz | MAJOR ENVELOPEGLYCOPROTEIN (Autographacalifornicamultiplenucleopolyhedrovirus) |
PF03273(Baculo_gp64) | 4 | LYS A 49LEU A 47ALA A 227LEU A 229 | None | 0.81A | 1ictB-3duzA:undetectable | 1ictB-3duzA:14.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f8u | TAPASIN (Homo sapiens) |
PF07654(C1-set) | 4 | ALA B 163LEU B 142SER B 161THR B 231 | NoneNoneNAG B1233 ( 4.6A)None | 0.96A | 1ictB-3f8uB:2.1 | 1ictB-3f8uB:15.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3fc8 | TRANSTHYRETIN (Homo sapiens) |
PF00576(Transthyretin) | 6 | LYS A 15LEU A 17ALA A 108LEU A 110SER A 117THR A 119 | IFA A3000 (-3.0A)IFA A3000 ( 4.7A)IFA A3000 (-3.1A)IFA A3000 (-4.1A)IFA A3000 (-3.9A)IFA A3000 ( 4.9A) | 0.66A | 1ictB-3fc8A:22.7 | 1ictB-3fc8A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fcm | HYDROLASE, NUDIXFAMILY (Clostridiumperfringens) |
PF00293(NUDIX) | 4 | LEU A 130LEU A 44SER A 76THR A 36 | None | 1.02A | 1ictB-3fcmA:undetectable | 1ictB-3fcmA:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i44 | ALDEHYDEDEHYDROGENASE (Bartonellahenselae) |
PF00171(Aldedh) | 4 | LEU A 173LEU A 146SER A 224THR A 226 | None | 0.89A | 1ictB-3i44A:undetectable | 1ictB-3i44A:13.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iwk | AMINOALDEHYDEDEHYDROGENASE (Pisum sativum) |
PF00171(Aldedh) | 4 | LEU A 184LEU A 157SER A 235THR A 237 | None | 0.88A | 1ictB-3iwkA:undetectable | 1ictB-3iwkA:13.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3iwu | 5-HYDROXYISOURATEHYDROLASE (Danio rerio) |
PF00576(Transthyretin) | 4 | LEU A 14LEU A 107SER A 114THR A 116 | None | 0.92A | 1ictB-3iwuA:19.5 | 1ictB-3iwuA:32.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j31 | A223 PENTON BASE (Sulfolobusturretedicosahedralvirus 1) |
no annotation | 4 | ALA Q 215LEU Q 217SER Q 165THR Q 167 | None | 0.81A | 1ictB-3j31Q:undetectable | 1ictB-3j31Q:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mcf | DIPHOSPHOINOSITOLPOLYPHOSPHATEPHOSPHOHYDROLASE3-ALPHA (Homo sapiens) |
PF00293(NUDIX) | 4 | LEU A 23ALA A 21LEU A 80THR A 93 | None | 1.00A | 1ictB-3mcfA:undetectable | 1ictB-3mcfA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mmt | FRUCTOSE-BISPHOSPHATE ALDOLASE (Bartonellahenselae) |
PF00274(Glycolytic) | 4 | LYS A 223ALA A 261LEU A 12THR A 290 | 2FP A 350 (-2.2A)NoneNoneNone | 1.00A | 1ictB-3mmtA:undetectable | 1ictB-3mmtA:15.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n4x | MONOPOLIN COMPLEXSUBUNIT CSM1 (Saccharomycescerevisiae) |
PF12539(Csm1) | 4 | LYS A 119ALA A 135SER A 162THR A 160 | None | 0.74A | 1ictB-3n4xA:undetectable | 1ictB-3n4xA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nuu | PKB-LIKE (Homo sapiens) |
PF00069(Pkinase) | 4 | LYS A 111LEU A 113LEU A 155THR A 148 | SO4 A 5 (-2.8A)NoneNoneSO4 A 369 (-3.7A) | 0.92A | 1ictB-3nuuA:undetectable | 1ictB-3nuuA:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3prx | COBRA VENOM FACTOR (Naja kaouthia) |
PF00207(A2M)PF01759(NTR)PF01821(ANATO)PF01835(A2M_N)PF07677(A2M_recep)PF07678(A2M_comp)PF07703(A2M_N_2)PF10569(Thiol-ester_cl) | 4 | LEU B 280LEU B 264SER B 317THR B 319 | None | 0.78A | 1ictB-3prxB:3.6 | 1ictB-3prxB:6.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qfo | PUTATIVEUNCHARACTERIZEDPROTEIN (Streptococcuspneumoniae) |
PF12850(Metallophos_2) | 4 | LEU A 37ALA A 61LEU A 36THR A 60 | None | 1.08A | 1ictB-3qfoA:undetectable | 1ictB-3qfoA:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r4i | CITRATE LYASE (Paraburkholderiaxenovorans) |
PF03328(HpcH_HpaI) | 4 | LEU A 148ALA A 155LEU A 149THR A 152 | None | 0.97A | 1ictB-3r4iA:undetectable | 1ictB-3r4iA:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ru8 | EPITOPE SCAFFOLD2BODX43 (Humanimmunodeficiencyvirus;Thermobifidafusca;syntheticconstruct) |
PF01341(Glyco_hydro_6) | 4 | LYS X 190ALA X 189SER X 148THR X 174 | None | 1.07A | 1ictB-3ru8X:undetectable | 1ictB-3ru8X:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ruy | ORNITHINEAMINOTRANSFERASE (Bacillusanthracis) |
PF00202(Aminotran_3) | 4 | LEU A 303ALA A 256LEU A 300SER A 296 | NoneLLP A 255 ( 3.6A)NoneNone | 1.07A | 1ictB-3ruyA:undetectable | 1ictB-3ruyA:17.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s3t | NUCLEOTIDE-BINDINGPROTEIN, UNIVERSALSTRESS PROTEIN USPAFAMILY (Lactobacillusplantarum) |
PF00582(Usp) | 4 | LEU A 36ALA A 83LEU A 86THR A 81 | None | 0.99A | 1ictB-3s3tA:undetectable | 1ictB-3s3tA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s51 | FANCONI ANEMIA GROUPI PROTEIN HOMOLOG (Mus musculus) |
PF14674(FANCI_S1-cap)PF14675(FANCI_S1)PF14676(FANCI_S2)PF14677(FANCI_S3)PF14678(FANCI_S4)PF14679(FANCI_HD1)PF14680(FANCI_HD2) | 4 | LYS A 197LEU A 193ALA A 196SER A 225 | None | 0.88A | 1ictB-3s51A:undetectable | 1ictB-3s51A:7.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sag | EXOSOME COMPONENT 10 (Homo sapiens) |
PF00570(HRDC)PF01612(DNA_pol_A_exo1) | 4 | LEU A 396ALA A 392LEU A 398THR A 389 | LEU A 396 ( 0.6A)ALA A 392 ( 0.0A)LEU A 398 ( 0.6A)THR A 389 ( 0.8A) | 0.97A | 1ictB-3sagA:undetectable | 1ictB-3sagA:14.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3swl | CHLORIDEINTRACELLULARCHANNEL PROTEIN 1 (Homo sapiens) |
PF13409(GST_N_2)PF13410(GST_C_2) | 4 | LEU A 180ALA A 176LEU A 181THR A 174 | None | 1.01A | 1ictB-3swlA:undetectable | 1ictB-3swlA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t6s | CERJ (Streptomycestendae) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 4 | LEU A 240ALA A 243LEU A 239THR A 187 | None | 1.05A | 1ictB-3t6sA:undetectable | 1ictB-3t6sA:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ttf | TRANSCRIPTIONALREGULATORY PROTEIN (Escherichiacoli) |
PF01300(Sua5_yciO_yrdC)PF07503(zf-HYPF) | 4 | LEU A 484ALA A 498SER A 695THR A 500 | None | 0.96A | 1ictB-3ttfA:undetectable | 1ictB-3ttfA:10.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ty7 | PUTATIVE ALDEHYDEDEHYDROGENASESAV2122 (Staphylococcusaureus) |
PF00171(Aldedh) | 4 | LEU A 169LEU A 142SER A 220THR A 222 | None | 0.92A | 1ictB-3ty7A:undetectable | 1ictB-3ty7A:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uog | ALCOHOLDEHYDROGENASE (Sinorhizobiummeliloti) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | LEU A 152ALA A 93SER A 66THR A 112 | None | 0.93A | 1ictB-3uogA:undetectable | 1ictB-3uogA:17.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ut3 | PLASMINOGENACTIVATOR INHIBITOR1 (Homo sapiens) |
PF00079(Serpin) | 4 | LYS A 323ALA A 168SER A 92THR A 94 | None | 0.92A | 1ictB-3ut3A:undetectable | 1ictB-3ut3A:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wa1 | BINB PROTEIN (Lysinibacillussphaericus) |
PF05431(Toxin_10) | 4 | LEU A 164ALA A 190LEU A 188SER A 159 | None | 1.03A | 1ictB-3wa1A:undetectable | 1ictB-3wa1A:15.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zef | PRE-MRNA-SPLICINGFACTOR 8 (Saccharomycescerevisiae) |
PF08084(PROCT)PF10596(U6-snRNA_bdg)PF10597(U5_2-snRNA_bdg)PF10598(RRM_4)PF12134(PRP8_domainIV) | 4 | LEU B1171ALA B1047LEU B1049SER B1249 | None | 0.94A | 1ictB-3zefB:undetectable | 1ictB-3zefB:7.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a7k | ALDOS-2-ULOSEDEHYDRATASE (Phanerochaetechrysosporium) |
no annotation | 4 | ALA A 893LEU A 891SER A 867THR A 852 | None | 0.92A | 1ictB-4a7kA:undetectable | 1ictB-4a7kA:10.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b4s | BCL-2-LIKE PROTEIN10 (Homo sapiens) |
PF00452(Bcl-2) | 4 | LEU A 130LEU A 16SER A 19THR A 95 | None | 1.06A | 1ictB-4b4sA:undetectable | 1ictB-4b4sA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bi9 | 3-KETOACYL-COATHIOLASE, PUTATIVE (Trypanosomabrucei) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 4 | LYS A 46LEU A 48SER A 87THR A 151 | None | 1.08A | 1ictB-4bi9A:undetectable | 1ictB-4bi9A:15.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ctd | OUTER MEMBRANEPROTEIN G (Escherichiacoli) |
PF09381(Porin_OmpG) | 4 | LEU A 167ALA A 195LEU A 197THR A 210 | NoneNoneNone CL A1274 (-4.2A) | 0.71A | 1ictB-4ctdA:undetectable | 1ictB-4ctdA:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d9i | DIAMINOPROPIONATEAMMONIA-LYASE (Escherichiacoli) |
PF00291(PALP) | 4 | LYS A 61LEU A 63LEU A 372THR A 225 | None | 0.98A | 1ictB-4d9iA:undetectable | 1ictB-4d9iA:16.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dyj | BROAD SPECIFICITYAMINO ACID RACEMASE (Pseudomonasputida) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | LEU A 257ALA A 243LEU A 241THR A 204 | None | 1.04A | 1ictB-4dyjA:undetectable | 1ictB-4dyjA:16.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f0d | POLY [ADP-RIBOSE]POLYMERASE 16 (Homo sapiens) |
PF00644(PARP) | 4 | LEU A 204ALA A 20LEU A 18SER A 99 | None | 1.08A | 1ictB-4f0dA:undetectable | 1ictB-4f0dA:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hea | NADH-QUINONEOXIDOREDUCTASESUBUNIT 13 (Thermusthermophilus) |
PF00361(Proton_antipo_M) | 4 | LEU M 260ALA M 297LEU M 263SER M 267 | None | 0.90A | 1ictB-4heaM:undetectable | 1ictB-4heaM:13.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i8q | PUTATIVE BETAINEALDEHYDEDEHYROGENASE (Solanumlycopersicum) |
PF00171(Aldedh) | 4 | LEU A 184LEU A 157SER A 235THR A 237 | NoneNoneNoneNAD A 601 (-4.2A) | 0.90A | 1ictB-4i8qA:undetectable | 1ictB-4i8qA:12.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jdz | SER-ASP RICHFIBRINOGEN/BONESIALOPROTEIN-BINDINGPROTEIN SDRD (Staphylococcusaureus) |
PF10425(SdrG_C_C)PF17210(SdrD_B) | 4 | LEU A 433ALA A 530LEU A 532THR A 542 | None | 0.75A | 1ictB-4jdzA:8.0 | 1ictB-4jdzA:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l1y | SALIVARY NITROPHORIN (Cimexlectularius) |
no annotation | 4 | LEU A 86ALA A 41SER A 13THR A 11 | None | 0.92A | 1ictB-4l1yA:undetectable | 1ictB-4l1yA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lc9 | GLUCOKINASEREGULATORY PROTEIN (Rattusnorvegicus) |
no annotation | 4 | LEU A 273ALA A 277LEU A 292THR A 280 | None | 1.08A | 1ictB-4lc9A:undetectable | 1ictB-4lc9A:12.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mdv | ANNEXIN (Schistosomamansoni) |
PF00191(Annexin) | 4 | LEU A 355LEU A 358SER A 320THR A 318 | None | 1.07A | 1ictB-4mdvA:undetectable | 1ictB-4mdvA:15.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mr0 | PLASMIN ANDFIBRONECTIN-BINDINGPROTEIN A (Streptococcuspneumoniae) |
PF12708(Pectate_lyase_3)PF13229(Beta_helix) | 4 | LYS A 426LEU A 424ALA A 470THR A 503 | None CA A 702 ( 4.5A)NoneNone | 0.73A | 1ictB-4mr0A:undetectable | 1ictB-4mr0A:12.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q9z | HUMAN PROTEIN KINASEC THETA (Homo sapiens) |
PF00069(Pkinase)PF00433(Pkinase_C) | 4 | LYS A 409LEU A 411LEU A 454THR A 447 | NoneNoneNoneSEP A 695 ( 4.8A) | 0.90A | 1ictB-4q9zA:undetectable | 1ictB-4q9zA:14.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qx8 | LYSINE-SPECIFICDEMETHYLASE 2A (Mus musculus) |
no annotation | 4 | LEU B 496LEU B 499SER B 502THR B 454 | None | 0.99A | 1ictB-4qx8B:undetectable | 1ictB-4qx8B:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qyb | UNCHARACTERIZEDPROTEIN (Burkholderiacenocepacia) |
PF10765(DUF2591) | 4 | LEU A 98ALA A 102SER A 94THR A 105 | None | 1.06A | 1ictB-4qybA:undetectable | 1ictB-4qybA:23.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r6g | LEUCINE RICH REPEATSDLRR_K (syntheticconstruct) |
PF12799(LRR_4)PF13516(LRR_6)PF13855(LRR_8) | 4 | LEU A 341ALA A 329LEU A 367SER A 365 | None | 1.04A | 1ictB-4r6gA:undetectable | 1ictB-4r6gA:13.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rqq | HUMAN ANTI-HIV-1ANTIBODY PGDM1400HEAVY CHAINHUMAN ANTI-HIV-1ANTIBODY PGDM1400LIGHT CHAIN (Homo sapiens) |
no annotation | 4 | LEU L 135ALA H 142SER H 137THR H 140 | None | 1.08A | 1ictB-4rqqL:undetectable | 1ictB-4rqqL:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tr6 | DNA POLYMERASE IIISUBUNIT BETA (Bacillussubtilis) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 4 | LEU A 373LEU A 361SER A 352THR A 354 | None | 0.82A | 1ictB-4tr6A:undetectable | 1ictB-4tr6A:15.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ut1 | FLAGELLARHOOK-ASSOCIATEDPROTEIN (Burkholderiapseudomallei) |
PF06429(Flg_bbr_C) | 4 | LEU A 278ALA A 212SER A 85THR A 81 | None | 0.94A | 1ictB-4ut1A:undetectable | 1ictB-4ut1A:10.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w65 | GLYCOSYL HYDROLASEFAMILY PROTEIN (Mycolicibacteriumfortuitum) |
PF00722(Glyco_hydro_16) | 4 | LEU A 109ALA A 101LEU A 103SER A 63 | LEU A 109 ( 0.6A)ALA A 101 ( 0.0A)LEU A 103 ( 0.6A)SER A 63 ( 0.0A) | 1.04A | 1ictB-4w65A:undetectable | 1ictB-4w65A:20.22 |