SIMILAR PATTERNS OF AMINO ACIDS FOR 1IBG_H_OBNH1_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cf5 PROTEIN
(BETA-MOMORCHARIN)

(Momordica
charantia) 		PF00161
(RIP) 		4 LEU A 112
PHE A  83
TYR A 140
VAL A  71
 None
 1.27A 1ibgH-1cf5A:
undetectable		 1ibgH-1cf5A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cii COLICIN IA

(Escherichia
coli) 		PF01024
(Colicin)
PF11504
(Colicin_Ia) 		4 LEU A 567
TRP A 551
PHE A 555
VAL A 559
 None
 1.33A 1ibgH-1ciiA:
0.0		 1ibgH-1ciiA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus) 		PF04616
(Glyco_hydro_43) 		4 LEU B 107
TRP B 138
PHE B  51
VAL B  40
 None
 1.30A 1ibgH-1gydB:
0.0		 1ibgH-1gydB:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lfw PEPV

(Lactobacillus
delbrueckii) 		PF01546
(Peptidase_M20) 		4 LEU A 149
PHE A 147
TYR A 457
VAL A  73
 None
 1.30A 1ibgH-1lfwA:
undetectable		 1ibgH-1lfwA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qni NITROUS-OXIDE
REDUCTASE

(Marinobacter
hydrocarbonoclasticus) 		no annotation 4 LEU A 272
PHE A 281
TYR A 194
VAL A 225
 None
 1.31A 1ibgH-1qniA:
0.0		 1ibgH-1qniA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uli BIPHENYL DIOXYGENASE
SMALL SUBUNIT

(Rhodococcus
jostii) 		PF00866
(Ring_hydroxyl_B) 		4 HIS B 111
LEU B  37
TRP B  45
VAL B 135
 None
 1.29A 1ibgH-1uliB:
undetectable		 1ibgH-1uliB:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w25 STALKED-CELL
DIFFERENTIATION
CONTROLLING PROTEIN

(Caulobacter
vibrioides) 		PF00072
(Response_reg)
PF00990
(GGDEF) 		4 HIS A 177
LEU A 152
TYR A 274
VAL A 265
 None
 1.31A 1ibgH-1w25A:
1.6		 1ibgH-1w25A:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wb0 CHITOTRIOSIDASE 1

(Homo sapiens) 		PF00704
(Glyco_hydro_18) 		4 LEU A 383
PHE A 342
TYR A 267
VAL A 339
 None
None
None
IPA  A1393 (-3.6A)
 1.08A 1ibgH-1wb0A:
undetectable		 1ibgH-1wb0A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wru 43 KDA TAIL PROTEIN

(Escherichia
virus Mu) 		PF05954
(Phage_GPD) 		4 LEU A 110
PHE A 174
TYR A 150
VAL A 125
 None
 1.31A 1ibgH-1wruA:
undetectable		 1ibgH-1wruA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xkd ISOCITRATE
DEHYDROGENASE

(Aeropyrum
pernix) 		PF00180
(Iso_dh) 		4 LEU A  30
PHE A 371
TYR A 132
VAL A 104
 None
 1.30A 1ibgH-1xkdA:
undetectable		 1ibgH-1xkdA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xvx YFUA

(Yersinia
enterocolitica) 		PF13343
(SBP_bac_6) 		4 LEU A 127
TRP A 132
PHE A 108
VAL A 194
 None
 1.12A 1ibgH-1xvxA:
undetectable		 1ibgH-1xvxA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xvy SFUA

(Yersinia
enterocolitica) 		PF13343
(SBP_bac_6) 		4 LEU A 124
TRP A 129
PHE A 105
VAL A 191
 None
 1.18A 1ibgH-1xvyA:
undetectable		 1ibgH-1xvyA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bv7 GLYCOLIPID TRANSFER
PROTEIN

(Bos taurus) 		PF08718
(GLTP) 		4 HIS A 140
LEU A 136
PHE A 148
VAL A 144
 GM3  A1212 (-3.6A)
GM3  A1212 (-4.3A)
GM3  A1212 (-4.6A)
None
 1.02A 1ibgH-2bv7A:
undetectable		 1ibgH-2bv7A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e8y AMYX PROTEIN

(Bacillus
subtilis) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		4 LEU A 131
PHE A 117
TYR A 110
VAL A 153
 None
 1.22A 1ibgH-2e8yA:
3.2		 1ibgH-2e8yA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus scrofa) 		PF05187
(ETF_QO)
PF13450
(NAD_binding_8) 		4 LEU A 223
PHE A 346
TYR A 402
VAL A 178
 None
 1.25A 1ibgH-2gmhA:
undetectable		 1ibgH-2gmhA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hwj HYPOTHETICAL PROTEIN
ATU1540

(Agrobacterium
fabrum) 		PF08857
(ParBc_2) 		4 HIS A 196
LEU A 197
TRP A 161
PHE A 164
 None
 1.20A 1ibgH-2hwjA:
undetectable		 1ibgH-2hwjA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oyo UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN

(Deinococcus
geothermalis) 		PF02627
(CMD) 		4 LEU A  30
TRP A  59
PHE A  45
VAL A  41
 None
 0.90A 1ibgH-2oyoA:
undetectable		 1ibgH-2oyoA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p87 PRE-MRNA-SPLICING
FACTOR PRP8

(Caenorhabditis
elegans) 		PF01398
(JAB)
PF08084
(PROCT) 		4 LEU A2156
TRP A2199
PHE A2120
VAL A2141
 None
 1.12A 1ibgH-2p87A:
undetectable		 1ibgH-2p87A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pn1 CARBAMOYLPHOSPHATE
SYNTHASE LARGE
SUBUNIT

(Exiguobacterium
sibiricum) 		PF02655
(ATP-grasp_3) 		4 LEU A   6
PHE A  21
TYR A 199
VAL A  18
 None
 1.15A 1ibgH-2pn1A:
undetectable		 1ibgH-2pn1A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pyx TRYPTOPHAN
HALOGENASE

(Shewanella
frigidimarina) 		PF04820
(Trp_halogenase) 		4 HIS A 410
LEU A 359
PHE A  93
VAL A 467
 None
 1.18A 1ibgH-2pyxA:
undetectable		 1ibgH-2pyxA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q4a CLAVAMINATE
SYNTHASE-LIKE
PROTEIN AT3G21360

(Arabidopsis
thaliana) 		PF02668
(TauD) 		4 HIS A 121
LEU A 312
TYR A  17
VAL A 246
 None
 1.31A 1ibgH-2q4aA:
undetectable		 1ibgH-2q4aA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qiw PEP PHOSPHONOMUTASE

(Corynebacterium
glutamicum) 		PF13714
(PEP_mutase) 		4 HIS A  15
LEU A  21
PHE A  11
VAL A 147
 None
GOL  A 258 (-4.6A)
None
None
 1.17A 1ibgH-2qiwA:
undetectable		 1ibgH-2qiwA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v5y RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE MU

(Homo sapiens) 		PF00041
(fn3)
PF00047
(ig)
PF00629
(MAM) 		4 LEU A 125
TRP A 110
PHE A  79
VAL A 155
 None
 1.29A 1ibgH-2v5yA:
6.2		 1ibgH-2v5yA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpw HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN

(Thermus
thermophilus) 		PF14589
(NrfD_2) 		4 HIS C  21
TRP C  14
PHE C  22
VAL C  25
 MQ7  C1252 (-4.1A)
MQ7  C1252 ( 4.5A)
None
None
 1.06A 1ibgH-2vpwC:
undetectable		 1ibgH-2vpwC:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vy2 PROTEIN LEAFY

(Arabidopsis
thaliana) 		PF17538
(C_LFY_FLO) 		4 LEU A 382
PHE A 367
TYR A 264
VAL A 366
 None
 1.26A 1ibgH-2vy2A:
undetectable		 1ibgH-2vy2A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w7z PENTAPEPTIDE REPEAT
FAMILY PROTEIN

(Enterococcus
faecalis) 		PF13599
(Pentapeptide_4) 		4 LEU A 182
TRP A 164
PHE A 174
VAL A 194
 None
None
None
LP6  A 193 ( 2.7A)
 1.30A 1ibgH-2w7zA:
undetectable		 1ibgH-2w7zA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wjz IMIDAZOLE GLYCEROL
PHOSPHATE SYNTHASE
SUBUNIT HISH

(Thermotoga
maritima) 		PF00117
(GATase) 		4 LEU B 189
PHE B 175
TYR B  79
VAL B  83
 None
 1.20A 1ibgH-2wjzB:
undetectable		 1ibgH-2wjzB:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x1c ACYL-COENZYME

(Penicillium
chrysogenum) 		PF03417
(AAT) 		4 LEU A 130
PHE A 315
TYR A 166
VAL A 328
 None
 0.96A 1ibgH-2x1cA:
undetectable		 1ibgH-2x1cA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xsg CCMAN5

(Cellulosimicrobium
cellulans) 		PF07971
(Glyco_hydro_92) 		4 HIS A  99
LEU A 117
TYR A  52
VAL A  82
 None
 1.34A 1ibgH-2xsgA:
2.4		 1ibgH-2xsgA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y3s TAML

(Streptomyces
sp. 307-9) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		4 LEU A 277
TRP A 231
PHE A 239
VAL A 243
 None
 1.21A 1ibgH-2y3sA:
undetectable		 1ibgH-2y3sA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2za1 OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE

(Plasmodium
falciparum) 		PF00215
(OMPdecase) 		4 LEU A 222
PHE A 239
TYR A 251
VAL A 190
 None
 1.23A 1ibgH-2za1A:
undetectable		 1ibgH-2za1A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a45 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE

(Acanthamoeba
polyphaga
mimivirus) 		PF01149
(Fapy_DNA_glyco)
PF06831
(H2TH) 		4 LEU A  14
TRP A  88
PHE A  64
VAL A  52
 None
 1.32A 1ibgH-3a45A:
undetectable		 1ibgH-3a45A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b8z PROTEIN ADAMTS-5

(Homo sapiens) 		PF01421
(Reprolysin) 		5 LEU A 328
TRP A 344
PHE A 341
TYR A 359
VAL A 396
 None
 1.49A 1ibgH-3b8zA:
undetectable		 1ibgH-3b8zA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c75 METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN

(Paracoccus
versutus) 		PF06433
(Me-amine-dh_H) 		4 HIS H 260
LEU H 266
TRP H 281
PHE H 259
 None
 1.29A 1ibgH-3c75H:
undetectable		 1ibgH-3c75H:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cia COLD-ACTIVE
AMINOPEPTIDASE

(Colwellia
psychrerythraea) 		PF01433
(Peptidase_M1)
PF09127
(Leuk-A4-hydro_C) 		4 LEU A 149
TRP A 177
TYR A 190
VAL A  61
 None
 1.31A 1ibgH-3ciaA:
undetectable		 1ibgH-3ciaA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e8j COPROPORPHYRINOGEN
III OXIDASE

(Leishmania
naiffi) 		PF01218
(Coprogen_oxidas) 		4 LEU A  13
PHE A  63
TYR A  67
VAL A  92
 None
 1.16A 1ibgH-3e8jA:
undetectable		 1ibgH-3e8jA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eeh PUTATIVE LIGHT AND
REDOX SENSING
HISTIDINE KINASE

(Haloarcula
marismortui) 		PF08447
(PAS_3) 		4 LEU A  31
PHE A  27
TYR A  41
VAL A 117
 None
 1.08A 1ibgH-3eehA:
undetectable		 1ibgH-3eehA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ehk PRUNIN

(Prunus dulcis) 		PF00190
(Cupin_1) 		4 HIS A 170
TRP A 191
PHE A 313
VAL A 314
 None
 1.20A 1ibgH-3ehkA:
undetectable		 1ibgH-3ehkA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eqq BENZENE
1,2-DIOXYGENASE
SUBUNIT BETA

(Pseudomonas
putida) 		PF00866
(Ring_hydroxyl_B) 		4 HIS B 111
LEU B  37
TRP B  45
VAL B 135
 None
 1.32A 1ibgH-3eqqB:
undetectable		 1ibgH-3eqqB:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ijd UNCHARACTERIZED
PROTEIN

(Ruminiclostridium
thermocellum) 		PF02219
(MTHFR) 		4 LEU A 231
TRP A 230
PHE A 227
VAL A 282
 C2F  A 314 (-3.9A)
None
C2F  A 315 (-3.7A)
C2F  A 315 (-4.7A)
 1.30A 1ibgH-3ijdA:
undetectable		 1ibgH-3ijdA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k5j SUPPRESSOR OF FUSED
FAMILY PROTEIN

(Neisseria
gonorrhoeae) 		PF05076
(SUFU) 		4 LEU A 128
PHE A  67
TYR A 169
VAL A  54
 None
None
GOL  A 187 ( 4.9A)
None
 1.21A 1ibgH-3k5jA:
undetectable		 1ibgH-3k5jA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kv0 HET-C2

(Podospora
anserina) 		PF08718
(GLTP) 		4 HIS A 147
LEU A 143
PHE A 155
VAL A 151
 None
MLY  A 144 ( 4.3A)
None
MLY  A 152 ( 3.2A)
 1.00A 1ibgH-3kv0A:
undetectable		 1ibgH-3kv0A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ld8 BIFUNCTIONAL
ARGININE DEMETHYLASE
AND
LYSYL-HYDROXYLASE
JMJD6

(Homo sapiens) 		PF02373
(JmjC) 		4 LEU A 160
PHE A 294
TYR A 313
VAL A 297
 None
None
SO4  A 352 ( 3.8A)
None
 1.23A 1ibgH-3ld8A:
undetectable		 1ibgH-3ld8A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lij CALCIUM/CALMODULIN
DEPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		4 LEU A 113
PHE A 206
TYR A 174
VAL A 204
 None
 1.24A 1ibgH-3lijA:
undetectable		 1ibgH-3lijA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE

(Sus scrofa) 		PF00305
(Lipoxygenase) 		4 LEU A 358
PHE A 415
TYR A 552
VAL A 409
 None
 1.17A 1ibgH-3rdeA:
undetectable		 1ibgH-3rdeA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqi KLLA0E03807P

(Kluyveromyces
lactis) 		PF16787
(NDC10_II) 		4 LEU A 225
PHE A 338
TYR A 205
VAL A 337
 None
 1.32A 1ibgH-3sqiA:
undetectable		 1ibgH-3sqiA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6g BREAST CANCER
ANTI-ESTROGEN
RESISTANCE PROTEIN 1
SH2
DOMAIN-CONTAINING
PROTEIN 3C

(Homo sapiens) 		PF00617
(RasGEF)
PF12026
(DUF3513) 		4 HIS B 790
LEU A 623
PHE B 794
VAL B 793
 None
 1.17A 1ibgH-3t6gB:
undetectable		 1ibgH-3t6gB:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66

(Autographa
californica
multiple
nucleopolyhedrovirus) 		PF04850
(Baculo_E66) 		4 TRP A 176
PHE A 123
TYR A 220
VAL A 126
 None
 1.23A 1ibgH-3vsmA:
undetectable		 1ibgH-3vsmA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wvi TYPE-2 RESTRICTION
ENZYME HINDIII

(Haemophilus
influenzae) 		PF09518
(RE_HindIII) 		4 LEU A 105
TRP A 192
PHE A  75
VAL A  94
 None
 1.24A 1ibgH-3wviA:
undetectable		 1ibgH-3wviA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4avc LYSINE
ACETYLTRANSFERASE

(Mycobacterium
tuberculosis) 		PF00027
(cNMP_binding)
PF13302
(Acetyltransf_3) 		4 LEU A 257
PHE A 224
TYR A 204
VAL A 266
 None
 1.22A 1ibgH-4avcA:
undetectable		 1ibgH-4avcA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4big UNCHARACTERIZED
LIPOPROTEIN
SAOUHSC_00053

(Staphylococcus
aureus) 		PF04507
(DUF576) 		4 LEU A 212
PHE A 232
TYR A  44
VAL A 195
 None
 1.27A 1ibgH-4bigA:
undetectable		 1ibgH-4bigA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bih UNCHARACTERIZED
LIPOPROTEIN
SAOUHSC_00053

(Staphylococcus
aureus) 		PF04507
(DUF576) 		4 LEU A 211
PHE A 231
TYR A  43
VAL A 194
 None
 1.33A 1ibgH-4bihA:
undetectable		 1ibgH-4bihA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dpy MEVALONATE
DIPHOSPHATE
DECARBOXYLASE

(Staphylococcus
epidermidis) 		PF00288
(GHMP_kinases_N) 		4 LEU A 176
TRP A 172
PHE A 150
VAL A  36
 None
 1.29A 1ibgH-4dpyA:
undetectable		 1ibgH-4dpyA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f1r CATABOLITE
REPRESSION CONTROL
PROTEIN

(Pseudomonas
aeruginosa) 		PF03372
(Exo_endo_phos) 		4 LEU A 257
PHE A  99
TYR A  56
VAL A 102
 None
 1.30A 1ibgH-4f1rA:
undetectable		 1ibgH-4f1rA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hl0 GALECTIN

(Toxascaris
leonina) 		PF00337
(Gal-bind_lectin) 		4 LEU A  25
TRP A 141
PHE A 128
VAL A 130
 None
 1.02A 1ibgH-4hl0A:
undetectable		 1ibgH-4hl0A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i7i RYANODINE RECEPTOR 1

(Oryctolagus
cuniculus) 		PF01365
(RYDR_ITPR)
PF02815
(MIR)
PF08709
(Ins145_P3_rec) 		4 LEU A 280
PHE A 316
TYR A 341
VAL A 348
 None
 0.94A 1ibgH-4i7iA:
undetectable		 1ibgH-4i7iA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i96 RYANODINE RECEPTOR 1

(Oryctolagus
cuniculus) 		PF01365
(RYDR_ITPR)
PF02815
(MIR) 		4 LEU A 280
PHE A 316
TYR A 341
VAL A 348
 None
 0.93A 1ibgH-4i96A:
undetectable		 1ibgH-4i96A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jg3 CATABOLITE
REPRESSION CONTROL
PROTEIN

(Pseudomonas
aeruginosa) 		PF03372
(Exo_endo_phos) 		4 LEU A 260
PHE A 102
TYR A  59
VAL A 105
 None
 1.30A 1ibgH-4jg3A:
undetectable		 1ibgH-4jg3A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kf6 GLYCOLIPID TRANSFER
PROTEIN
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF08718
(GLTP) 		4 HIS A 150
LEU A 146
TRP A 117
VAL A 154
 1T9  A 301 (-4.5A)
1T9  A 301 (-4.6A)
1T9  A 301 (-4.0A)
1T9  A 301 ( 4.1A)
 1.13A 1ibgH-4kf6A:
undetectable		 1ibgH-4kf6A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lu6 FLAVIN-DEPENDENT
TRYPTOPHAN
HALOGENASE REBH

(Lechevalieria
aerocolonigenes) 		PF04820
(Trp_halogenase) 		4 HIS A 406
LEU A 356
PHE A  84
VAL A 474
 None
 1.14A 1ibgH-4lu6A:
undetectable		 1ibgH-4lu6A:
16.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4m1g MURINE IGG2A A27D7
HEAVY CHAIN FAB
DOMAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 HIS H  98
LEU H 105
TRP H 108
VAL H  50
 None
 1.20A 1ibgH-4m1gH:
27.6		 1ibgH-4m1gH:
82.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Anaerococcus
prevotii) 		PF03480
(DctP) 		4 LEU A 254
TRP A 250
PHE A 262
VAL A 261
 None
 1.30A 1ibgH-4n91A:
undetectable		 1ibgH-4n91A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nn0 COMPLEMENT C1Q TUMOR
NECROSIS
FACTOR-RELATED
PROTEIN 5

(Homo sapiens) 		PF00386
(C1q) 		4 LEU A 168
PHE A 153
TYR A 136
VAL A 197
 None
 1.23A 1ibgH-4nn0A:
undetectable		 1ibgH-4nn0A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oo0 MAF-LIKE PROTEIN
BCAL2394

(Burkholderia
cenocepacia) 		PF02545
(Maf) 		4 HIS A 125
LEU A 120
PHE A 152
VAL A 150
 None
 1.31A 1ibgH-4oo0A:
undetectable		 1ibgH-4oo0A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p0e MAF-LIKE PROTEIN
YHDE

(Escherichia
coli) 		PF02545
(Maf) 		4 HIS A 101
LEU A  96
PHE A 126
VAL A 124
 None
 1.33A 1ibgH-4p0eA:
undetectable		 1ibgH-4p0eA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pbc D-AMINO ACID
AMINOTRANSFERASE

(Burkholderia
cenocepacia) 		PF01063
(Aminotran_4) 		4 LEU A  71
TRP A  92
TYR A  19
VAL A  53
 None
 1.15A 1ibgH-4pbcA:
undetectable		 1ibgH-4pbcA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pet EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 7

(Colwellia
psychrerythraea) 		PF03480
(DctP) 		4 LEU A 222
TRP A 217
PHE A  49
TYR A 101
 None
PYR  A 402 ( 4.1A)
PYR  A 402 (-4.2A)
None
 1.32A 1ibgH-4petA:
undetectable		 1ibgH-4petA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qc8 VP2

(Ungulate
bocaparvovirus
1) 		PF00740
(Parvo_coat) 		4 LEU A 117
TRP A 114
PHE A 124
VAL A 484
 None
 1.33A 1ibgH-4qc8A:
undetectable		 1ibgH-4qc8A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r04 TOXIN A

(Clostridioides
difficile) 		PF11713
(Peptidase_C80)
PF12918
(TcdB_N)
PF12919
(TcdA_TcdB)
PF12920
(TcdA_TcdB_pore) 		4 LEU A 673
PHE A 652
TYR A 636
VAL A 695
 None
 0.76A 1ibgH-4r04A:
undetectable		 1ibgH-4r04A:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r27 GLYCOSIDE HYDROLASE

(Microbacterium
sp. Gsoil167) 		PF00232
(Glyco_hydro_1) 		4 LEU A 251
TRP A 249
PHE A 277
VAL A 273
 None
 0.94A 1ibgH-4r27A:
undetectable		 1ibgH-4r27A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r33 NOSL

(Streptomyces
actuosus) 		PF06968
(BATS) 		4 HIS A 267
LEU A 271
PHE A 234
VAL A 231
 None
 1.24A 1ibgH-4r33A:
undetectable		 1ibgH-4r33A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r81 NADH DEHYDROGENASE

(Methanothermobacter
marburgensis) 		PF02525
(Flavodoxin_2) 		4 LEU A  97
TRP A 100
PHE A  84
VAL A 129
 None
 0.90A 1ibgH-4r81A:
undetectable		 1ibgH-4r81A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tm5 D-AMINO ACID
AMINOTRANSFERASE

(Burkholderia
thailandensis) 		PF01063
(Aminotran_4) 		4 LEU A  63
TRP A  84
TYR A  11
VAL A  45
 None
 1.04A 1ibgH-4tm5A:
undetectable		 1ibgH-4tm5A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4udn PERIPLASMIC SOLUTE
BINDING PROTEIN

(Candidatus
Liberibacter
asiaticus) 		PF01297
(ZnuA) 		4 LEU A  64
PHE A  11
TYR A 259
VAL A  32
 None
 1.24A 1ibgH-4udnA:
undetectable		 1ibgH-4udnA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uek GALACTITOL-1-PHOSPHA
TE 5-DEHYDROGENASE

(Escherichia
coli) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 LEU A 344
PHE A 323
TYR A 120
VAL A   4
 None
 1.24A 1ibgH-4uekA:
undetectable		 1ibgH-4uekA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uwa RYANODINE RECEPTOR 1

(Oryctolagus
cuniculus) 		PF00622
(SPRY)
PF01365
(RYDR_ITPR)
PF02026
(RyR)
PF02815
(MIR)
PF08709
(Ins145_P3_rec) 		4 LEU A 280
PHE A 316
TYR A 341
VAL A 348
 None
 0.96A 1ibgH-4uwaA:
undetectable		 1ibgH-4uwaA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x9f DOWN SYNDROME CELL
ADHESION MOLECULE
ISOFORM 6.9

(Drosophila
melanogaster) 		PF07679
(I-set) 		4 HIS A 186
LEU A 188
PHE A 134
VAL A 135
 None
 1.09A 1ibgH-4x9fA:
8.9		 1ibgH-4x9fA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xl1 DELTA-LIKE PROTEIN

(Rattus
norvegicus) 		PF01414
(DSL)
PF07657
(MNNL) 		4 LEU B  62
PHE B  30
TYR B 169
VAL B 173
 MLY  B  63 ( 3.6A)
None
None
None
 1.32A 1ibgH-4xl1B:
undetectable		 1ibgH-4xl1B:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yyc PUTATIVE
TRIMETHYLAMINE
METHYLTRANSFERASE

(Sinorhizobium
meliloti) 		PF06253
(MTTB) 		4 LEU A 313
PHE A 387
TYR A 140
VAL A 135
 None
 1.33A 1ibgH-4yycA:
undetectable		 1ibgH-4yycA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zcf RESTRICTION
ENDONUCLEASE
ECOP15I, RESTRICTION
SUBUNIT

(Escherichia
coli) 		PF04851
(ResIII) 		4 HIS C 135
LEU C   7
PHE C 136
TYR C  94
 None
 1.14A 1ibgH-4zcfC:
undetectable		 1ibgH-4zcfC:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zzq CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Dictyostelium
discoideum) 		PF00840
(Glyco_hydro_7) 		4 LEU A 145
PHE A 126
TYR A 424
VAL A 429
 None
 1.04A 1ibgH-4zzqA:
undetectable		 1ibgH-4zzqA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cd2 ENDO-1,4-D-GLUCANASE

(Aliivibrio
fischeri) 		PF01270
(Glyco_hydro_8) 		4 LEU A 271
PHE A 366
TYR A 143
VAL A 362
 None
 1.20A 1ibgH-5cd2A:
undetectable		 1ibgH-5cd2A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cm6 TRAP DICARBOXYLATE
TRANSPORTER-DCTP
SUBUNIT

(Pseudoalteromonas
atlantica) 		PF03480
(DctP) 		4 LEU A 216
TRP A 211
PHE A  43
TYR A  95
 None
None
PYR  A 401 ( 4.2A)
PYR  A 401 (-4.6A)
 1.30A 1ibgH-5cm6A:
undetectable		 1ibgH-5cm6A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e4m HYDROXYNITRILE LYASE

(Davallia
tyermannii) 		no annotation 5 LEU A 168
TRP A  47
PHE A 136
TYR A  99
VAL A 134
 None
 1.45A 1ibgH-5e4mA:
undetectable		 1ibgH-5e4mA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5efv PHI ETA ORF 56-LIKE
PROTEIN

(Staphylococcus
virus 11) 		no annotation 4 LEU A 156
PHE A 167
TYR A 342
VAL A 169
 None
 1.23A 1ibgH-5efvA:
undetectable		 1ibgH-5efvA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE

(Cupriavidus
metallidurans) 		PF13231
(PMT_2) 		4 LEU A 551
TRP A 529
PHE A 525
VAL A 522
 None
 1.02A 1ibgH-5f15A:
undetectable		 1ibgH-5f15A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fn4 NICASTRIN

(Homo sapiens) 		PF05450
(Nicastrin) 		4 HIS A 553
LEU A 551
PHE A 525
VAL A 299
 None
 1.34A 1ibgH-5fn4A:
undetectable		 1ibgH-5fn4A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5g PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT

(Escherichia
coli) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 HIS C 304
LEU C 289
TYR C 717
VAL C 320
 None
 1.33A 1ibgH-5g5gC:
undetectable		 1ibgH-5g5gC:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l3q SIGNAL RECOGNITION
PARTICLE RECEPTOR
SUBUNIT ALPHA

(Homo sapiens) 		PF00448
(SRP54)
PF02881
(SRP54_N) 		4 LEU B 623
TRP B 441
PHE B 613
VAL B 586
 None
 1.28A 1ibgH-5l3qB:
undetectable		 1ibgH-5l3qB:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l56 PLEXIN-A1

(Mus musculus) 		PF01403
(Sema)
PF01437
(PSI)
PF01833
(TIG) 		4 LEU A 580
PHE A 654
TYR A 657
VAL A 652
 None
 1.23A 1ibgH-5l56A:
3.5		 1ibgH-5l56A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lva NAD(P)H-FMN
OXIDOREDUCTASE

(Bacillus
subtilis) 		PF02525
(Flavodoxin_2) 		4 LEU A  75
TRP A  78
PHE A  62
VAL A 103
 None
 0.92A 1ibgH-5lvaA:
undetectable		 1ibgH-5lvaA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m59 PUTATIVE PRE-MRNA
SPLICING FACTOR

(Chaetomium
thermophilum) 		PF08084
(PROCT) 		4 LEU B2136
TRP B2180
PHE B2100
VAL B2121
 None
 1.28A 1ibgH-5m59B:
undetectable		 1ibgH-5m59B:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ode GLL2934 PROTEIN

(Gloeobacter
violaceus) 		no annotation 4 LEU A  42
PHE A 116
TYR A 106
VAL A 102
 None
 1.09A 1ibgH-5odeA:
undetectable		 1ibgH-5odeA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oom 39S RIBOSOMAL
PROTEIN L39,
MITOCHONDRIAL

(Homo sapiens) 		no annotation 4 LEU 7 189
TRP 7 192
PHE 7 158
VAL 7 164
 None
 1.29A 1ibgH-5oom7:
undetectable		 1ibgH-5oom7:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vae ACCESSORY SEC SYSTEM
PROTEIN ASP1

(Streptococcus
gordonii) 		no annotation 4 LEU A 426
PHE A 326
TYR A 360
VAL A 356
 None
 1.25A 1ibgH-5vaeA:
undetectable		 1ibgH-5vaeA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xsy SODIUM CHANNEL
PROTEIN

(Electrophorus
electricus) 		PF00520
(Ion_trans)
PF06512
(Na_trans_assoc) 		4 HIS A 176
LEU A 180
PHE A 179
VAL A 167
 None
 1.26A 1ibgH-5xsyA:
undetectable		 1ibgH-5xsyA:
7.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xx9 BACTERIOFERRITIN

(Streptomyces
coelicolor) 		no annotation 4 LEU A 138
PHE A  87
TYR A  43
VAL A  83
 None
 1.15A 1ibgH-5xx9A:
undetectable		 1ibgH-5xx9A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cip PYRUVATE-FERREDOXIN
OXIDOREDUCTASE

(Moorella
thermoacetica) 		no annotation 4 LEU A 288
PHE A 376
TYR A 261
VAL A 372
 None
 1.23A 1ibgH-6cipA:
undetectable		 1ibgH-6cipA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6erc PEROXINECTIN A

(Dictyostelium
discoideum) 		no annotation 4 HIS A 244
LEU A 240
TYR A 290
VAL A 174
 None
 1.23A 1ibgH-6ercA:
undetectable		 1ibgH-6ercA:
16.10