SIMILAR PATTERNS OF AMINO ACIDS FOR 1HXB_A_ROCA100_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ad1 DIHYDROPTEROATE
SYNTHETASE

(Staphylococcus
aureus) 		PF00809
(Pterin_bind) 		3 ARG A  87
THR A  13
VAL A  49
 None
 0.92A 1hxbA-1ad1A:
0.0		 1hxbA-1ad1A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d1t ALCOHOL
DEHYDROGENASE CLASS
IV SIGMA CHAIN

(Homo sapiens) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		3 ARG A 120
THR A 128
VAL A 122
 None
ACT  A 502 ( 4.3A)
None
 0.96A 1hxbA-1d1tA:
0.0		 1hxbA-1d1tA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e8c UDP-N-ACETYLMURAMOYL
ALANYL-D-GLUTAMATE--
2,6-DIAMINOPIMELATE
LIGASE

(Escherichia
coli) 		PF01225
(Mur_ligase)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M) 		3 ARG A 341
THR A 154
VAL A 143
 None
 0.99A 1hxbA-1e8cA:
0.0		 1hxbA-1e8cA:
11.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1hvc HIV-1 PROTEASE

(Human
immunodeficiency
virus 1) 		PF00077
(RVP) 		3 ARG A   8
THR A  80
VAL A  82
 A79  A 800 (-3.6A)
None
A79  A 800 (-4.5A)
 0.74A 1hxbA-1hvcA:
14.0		 1hxbA-1hvcA:
48.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k3r CONSERVED PROTEIN
MT0001

(Methanothermobacter
thermautotrophicus) 		PF02598
(Methyltrn_RNA_3) 		3 ARG A  71
THR A  25
VAL A  84
 None
 0.96A 1hxbA-1k3rA:
0.0		 1hxbA-1k3rA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m3v FUSION OF THE LIM
INTERACTING DOMAIN
OF LDB1 AND THE
N-TERMINAL LIM
DOMAIN OF LMO4

(Mus musculus) 		PF00412
(LIM) 		3 ARG A  59
THR A  91
VAL A  86
 None
 0.97A 1hxbA-1m3vA:
undetectable		 1hxbA-1m3vA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nug PROTEIN-GLUTAMINE
GLUTAMYLTRANSFERASE
E

(Homo sapiens) 		PF00868
(Transglut_N)
PF00927
(Transglut_C)
PF01841
(Transglut_core) 		3 ARG A 247
THR A 294
VAL A 164
 None
 1.00A 1hxbA-1nugA:
0.0		 1hxbA-1nugA:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qrz PLASMINOGEN

(Homo sapiens) 		PF00089
(Trypsin) 		3 ARG A 776
THR A 678
VAL A 674
 None
 0.94A 1hxbA-1qrzA:
0.4		 1hxbA-1qrzA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1srv PROTEIN (GROEL
(HSP60 CLASS))

(Thermus
thermophilus) 		PF00118
(Cpn60_TCP1) 		3 ARG A 322
THR A 206
VAL A 214
 None
 0.95A 1hxbA-1srvA:
0.0		 1hxbA-1srvA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vyv CALCIUM CHANNEL
BETA-4SUBUNIT

(Rattus
norvegicus) 		PF00625
(Guanylate_kin)
PF12052
(VGCC_beta4Aa_N) 		3 ARG A 160
THR A  98
VAL A 100
 None
 0.88A 1hxbA-1vyvA:
undetectable		 1hxbA-1vyvA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2asu HEPATOCYTE GROWTH
FACTOR-LIKE PROTEIN

(Homo sapiens) 		PF00089
(Trypsin) 		3 ARG B 696
THR B 600
VAL B 596
 None
 0.93A 1hxbA-2asuB:
1.0		 1hxbA-2asuB:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2atc ASPARTATE
CARBAMOYLTRANSFERASE
, CATALYTIC CHAIN

(Escherichia
coli) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		3 ARG A 264
THR A 275
VAL A 272
 None
 0.76A 1hxbA-2atcA:
undetectable		 1hxbA-2atcA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b5u COLICIN E3

(Escherichia
coli) 		PF03515
(Cloacin)
PF09000
(Cytotoxic)
PF11570
(E2R135) 		3 ARG A 273
THR A 165
VAL A 169
 None
 0.87A 1hxbA-2b5uA:
undetectable		 1hxbA-2b5uA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN

(Moritella
profunda) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		3 ARG A 269
THR A 280
VAL A 277
 None
 0.92A 1hxbA-2be7A:
undetectable		 1hxbA-2be7A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bgk RHIZOME
SECOISOLARICIRESINOL
DEHYDROGENASE

(Podophyllum
peltatum) 		PF13561
(adh_short_C2) 		3 ARG A 138
THR A  86
VAL A  83
 None
 0.97A 1hxbA-2bgkA:
undetectable		 1hxbA-2bgkA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bov MONO-ADP-RIBOSYLTRAN
SFERASE C3
RAS-RELATED PROTEIN
RAL-A

(Clostridium
botulinum;
Homo sapiens) 		PF00071
(Ras)
PF03496
(ADPrib_exo_Tox) 		3 ARG A 135
THR B1080
VAL B1077
 None
 0.96A 1hxbA-2bovA:
undetectable		 1hxbA-2bovA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d0i DEHYDROGENASE

(Pyrococcus
horikoshii) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		3 ARG A 236
THR A 259
VAL A 261
 None
 0.99A 1hxbA-2d0iA:
undetectable		 1hxbA-2d0iA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e7z ACETYLENE HYDRATASE
AHY

(Pelobacter
acetylenicus) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		3 ARG A 523
THR A 480
VAL A 468
 None
 0.97A 1hxbA-2e7zA:
undetectable		 1hxbA-2e7zA:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gjm LACTOPEROXIDASE

(Bubalus bubalis) 		PF03098
(An_peroxidase) 		3 ARG A 239
THR A 168
VAL A 167
 HEM  A 605 (-4.7A)
CA  A1503 (-3.8A)
None
 1.02A 1hxbA-2gjmA:
undetectable		 1hxbA-2gjmA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hi8 SULFATASE-MODIFYING
FACTOR 1

(Homo sapiens) 		PF03781
(FGE-sulfatase) 		3 ARG X 189
THR X 143
VAL X 140
 None
 0.99A 1hxbA-2hi8X:
undetectable		 1hxbA-2hi8X:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hj9 AUTOINDUCER
2-BINDING
PERIPLASMIC PROTEIN
LUXP

(Vibrio harveyi) 		PF13407
(Peripla_BP_4) 		3 ARG A 351
THR A 307
VAL A 343
 None
 1.01A 1hxbA-2hj9A:
undetectable		 1hxbA-2hj9A:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ip1 TRYPTOPHANYL-TRNA
SYNTHETASE

(Saccharomyces
cerevisiae) 		PF00579
(tRNA-synt_1b) 		3 ARG A 448
THR A 455
VAL A 451
 None
 0.79A 1hxbA-2ip1A:
undetectable		 1hxbA-2ip1A:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o5p FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa) 		PF00593
(TonB_dep_Rec)
PF07660
(STN)
PF07715
(Plug) 		3 ARG A 643
THR A 706
VAL A 704
 None
 0.87A 1hxbA-2o5pA:
undetectable		 1hxbA-2o5pA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q4q UPF0366 PROTEIN
C11ORF67

(Homo sapiens) 		PF04430
(DUF498) 		3 ARG A  69
THR A  81
VAL A  77
 None
 0.95A 1hxbA-2q4qA:
undetectable		 1hxbA-2q4qA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qfr PURPLE ACID
PHOSPHATASE

(Phaseolus
vulgaris) 		PF00149
(Metallophos)
PF14008
(Metallophos_C)
PF16656
(Pur_ac_phosph_N) 		3 ARG A 222
THR A  48
VAL A  47
 None
 0.93A 1hxbA-2qfrA:
undetectable		 1hxbA-2qfrA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qpq PROTEIN BUG27

(Bordetella
pertussis) 		PF03401
(TctC) 		3 ARG A  27
THR A  15
VAL A  14
 None
 0.91A 1hxbA-2qpqA:
undetectable		 1hxbA-2qpqA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE

(Bacillus
anthracis) 		PF13561
(adh_short_C2) 		3 ARG A 126
THR A  76
VAL A  73
 None
 0.74A 1hxbA-2uvdA:
undetectable		 1hxbA-2uvdA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vda TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli) 		PF01043
(SecA_PP_bind)
PF07516
(SecA_SW)
PF07517
(SecA_DEAD) 		3 ARG A 509
THR A 178
VAL A 131
 None
 0.90A 1hxbA-2vdaA:
undetectable		 1hxbA-2vdaA:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wae PENICILLIN-BINDING
PROTEIN 2B

(Streptococcus
pneumoniae) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		3 ARG A 223
THR A 265
VAL A 237
 None
 1.01A 1hxbA-2waeA:
undetectable		 1hxbA-2waeA:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x9x CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
pneumoniae) 		PF16569
(GramPos_pilinBB)
PF16570
(GramPos_pilinD3) 		3 ARG A 480
THR A 496
VAL A 493
 None
 0.87A 1hxbA-2x9xA:
undetectable		 1hxbA-2x9xA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yfq NAD-SPECIFIC
GLUTAMATE
DEHYDROGENASE

(Peptoniphilus
asaccharolyticus) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		3 ARG A  59
THR A 149
VAL A  73
 None
 0.83A 1hxbA-2yfqA:
undetectable		 1hxbA-2yfqA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zj4 GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING] 1

(Homo sapiens) 		PF01380
(SIS) 		3 ARG A 501
THR A 383
VAL A 386
 None
 0.98A 1hxbA-2zj4A:
undetectable		 1hxbA-2zj4A:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aoe GLUTAMATE
DEHYDROGENASE

(Thermus
thermophilus) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		3 ARG A  67
THR A 157
VAL A  81
 None
 0.91A 1hxbA-3aoeA:
undetectable		 1hxbA-3aoeA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aqp PROBABLE SECDF
PROTEIN-EXPORT
MEMBRANE PROTEIN

(Thermus
thermophilus) 		PF02355
(SecD_SecF)
PF07549
(Sec_GG) 		3 ARG A 695
THR A 513
VAL A 515
 None
 1.00A 1hxbA-3aqpA:
undetectable		 1hxbA-3aqpA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cdd PROPHAGE MUSO2, 43
KDA TAIL PROTEIN

(Shewanella
oneidensis) 		PF05954
(Phage_GPD) 		3 ARG A  94
THR A 152
VAL A 101
 None
 0.89A 1hxbA-3cddA:
undetectable		 1hxbA-3cddA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3csv AMINOGLYCOSIDE
PHOSPHOTRANSFERASE

(Ruegeria sp.
TM1040) 		PF01636
(APH) 		3 ARG A 219
THR A 128
VAL A 183
 None
 1.01A 1hxbA-3csvA:
undetectable		 1hxbA-3csvA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ctz XAA-PRO
AMINOPEPTIDASE 1

(Homo sapiens) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N)
PF16188
(Peptidase_M24_C)
PF16189
(Creatinase_N_2) 		3 ARG A 429
THR A 425
VAL A 427
 None
 0.93A 1hxbA-3ctzA:
undetectable		 1hxbA-3ctzA:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d37 TAIL PROTEIN, 43 KDA

(Neisseria
meningitidis) 		no annotation 3 ARG A  92
THR A 150
VAL A  99
 None
CL  A 383 ( 4.1A)
CL  A 383 ( 4.0A)
 0.70A 1hxbA-3d37A:
undetectable		 1hxbA-3d37A:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dc8 DIHYDROPYRIMIDINASE

(Sinorhizobium
meliloti) 		PF01979
(Amidohydro_1) 		3 ARG A 452
THR A  57
VAL A  88
 None
 1.00A 1hxbA-3dc8A:
undetectable		 1hxbA-3dc8A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dmy PROTEIN FDRA

(Escherichia
coli) 		PF00549
(Ligase_CoA)
PF02629
(CoA_binding) 		3 ARG A 321
THR A 453
VAL A 479
 None
 0.99A 1hxbA-3dmyA:
undetectable		 1hxbA-3dmyA:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ek3 NITROREDUCTASE

(Bacteroides
fragilis) 		PF00881
(Nitroreductase) 		3 ARG A 146
THR A  51
VAL A 154
 None
 0.92A 1hxbA-3ek3A:
undetectable		 1hxbA-3ek3A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3glq ADENOSYLHOMOCYSTEINA
SE

(Burkholderia
pseudomallei) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		3 ARG A 384
THR A 354
VAL A 351
 None
 0.36A 1hxbA-3glqA:
undetectable		 1hxbA-3glqA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY

(Agrobacterium
fabrum) 		PF13377
(Peripla_BP_3) 		3 ARG A 204
THR A 225
VAL A 192
 None
 0.93A 1hxbA-3gv0A:
undetectable		 1hxbA-3gv0A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hag CAPSID PROTEIN

(Orthohepevirus
A) 		PF03014
(SP2) 		3 ARG A 460
THR A 520
VAL A 464
 None
 0.76A 1hxbA-3hagA:
undetectable		 1hxbA-3hagA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k92 NAD-SPECIFIC
GLUTAMATE
DEHYDROGENASE

(Bacillus
subtilis) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		3 ARG A  69
THR A 159
VAL A  83
 None
 0.89A 1hxbA-3k92A:
undetectable		 1hxbA-3k92A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lpn RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE

(Thermoplasma
volcanium) 		PF00156
(Pribosyltran)
PF13793
(Pribosyltran_N) 		3 ARG A 167
THR A 263
VAL A 239
 None
 0.99A 1hxbA-3lpnA:
undetectable		 1hxbA-3lpnA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lxm ASPARTATE
CARBAMOYLTRANSFERASE

(Yersinia pestis) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		3 ARG A 270
THR A 281
VAL A 278
 None
 0.94A 1hxbA-3lxmA:
undetectable		 1hxbA-3lxmA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN

(Escherichia
virus Qbeta) 		no annotation 3 ARG G 431
THR G 462
VAL G 473
 None
 1.01A 1hxbA-3mmpG:
undetectable		 1hxbA-3mmpG:
13.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3mws HIV-1 PROTEASE

(Human
immunodeficiency
virus 1) 		PF00077
(RVP) 		3 ARG A   8
THR A  80
VAL A  82
 None
 0.55A 1hxbA-3mwsA:
19.6		 1hxbA-3mwsA:
77.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o0r NITRIC OXIDE
REDUCTASE SUBUNIT B

(Pseudomonas
aeruginosa) 		PF00115
(COX1) 		3 ARG B 234
THR B 230
VAL B 227
 None
 0.85A 1hxbA-3o0rB:
undetectable		 1hxbA-3o0rB:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)

(Corynebacterium
glutamicum) 		PF01370
(Epimerase)
PF08338
(DUF1731) 		3 ARG A 226
THR A 233
VAL A 230
 None
 1.01A 1hxbA-3oh8A:
undetectable		 1hxbA-3oh8A:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p1v METALLO-ENDOPEPTIDAS
E

(Bacteroides
ovatus) 		PF09471
(Peptidase_M64)
PF16217
(M64_N) 		3 ARG A 134
THR A 348
VAL A 339
 None
 0.97A 1hxbA-3p1vA:
undetectable		 1hxbA-3p1vA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qsz STAR-RELATED LIPID
TRANSFER PROTEIN

(Xanthomonas
citri) 		PF01852
(START) 		3 ARG A  50
THR A 188
VAL A 185
 None
 0.70A 1hxbA-3qszA:
undetectable		 1hxbA-3qszA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s1s RESTRICTION
ENDONUCLEASE BPUSI

(Bacillus
pumilus) 		PF02384
(N6_Mtase)
PF15516
(BpuSI_N) 		3 ARG A 648
THR A 663
VAL A 665
 None
 0.94A 1hxbA-3s1sA:
undetectable		 1hxbA-3s1sA:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v68 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pyrococcus
furiosus) 		PF10869
(DUF2666) 		3 ARG A 227
THR A 106
VAL A 237
 None
 0.94A 1hxbA-3v68A:
undetectable		 1hxbA-3v68A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v8x TRANSFERRIN-BINDING
PROTEIN 1

(Neisseria
meningitidis) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 ARG A 132
THR A 295
VAL A 345
 None
 0.96A 1hxbA-3v8xA:
undetectable		 1hxbA-3v8xA:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vxi DYP

(Bjerkandera
adusta) 		PF04261
(Dyp_perox) 		3 ARG A 263
THR A 312
VAL A 309
 HEM  A 501 (-4.2A)
HEM  A 501 (-3.5A)
HEM  A 501 (-4.4A)
 0.84A 1hxbA-3vxiA:
undetectable		 1hxbA-3vxiA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bil DNA MATURASE B

(Escherichia
virus T7) 		no annotation 3 ARG A 326
THR A 467
VAL A 464
 None
 0.98A 1hxbA-4bilA:
undetectable		 1hxbA-4bilA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c2k 3-KETOACYL-COA
THIOLASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		3 ARG A 130
THR A 153
VAL A 150
 None
EDO  A1397 (-3.5A)
None
 1.01A 1hxbA-4c2kA:
undetectable		 1hxbA-4c2kA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ckb MRNA-CAPPING ENZYME
CATALYTIC SUBUNIT

(Vaccinia virus) 		PF03291
(Pox_MCEL)
PF10640
(Pox_ATPase-GT) 		3 ARG A 548
THR A 759
VAL A 553
 SAH  A1845 (-3.4A)
None
None
 0.95A 1hxbA-4ckbA:
undetectable		 1hxbA-4ckbA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4duu PLASMINOGEN

(Homo sapiens) 		PF00024
(PAN_1)
PF00051
(Kringle)
PF00089
(Trypsin) 		3 ARG A 776
THR A 678
VAL A 674
 None
 0.92A 1hxbA-4duuA:
undetectable		 1hxbA-4duuA:
7.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eq5 DNA LIGASE

(Thermococcus
sibiricus) 		PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C) 		3 ARG A 454
THR A 492
VAL A 457
 None
 0.89A 1hxbA-4eq5A:
undetectable		 1hxbA-4eq5A:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fwt ELONGATION FACTOR
TS, ELONGATION
FACTOR TU, LINKER, Q
BETA REPLICASE

(Escherichia
coli;
Escherichia
virus Qbeta) 		PF00009
(GTP_EFTU)
PF00889
(EF_TS)
PF03143
(GTP_EFTU_D3)
PF03144
(GTP_EFTU_D2)
PF03431
(RNA_replicase_B) 		3 ARG A1125
THR A1156
VAL A1167
 A  G2005 ( 4.7A)
None
None
 1.00A 1hxbA-4fwtA:
undetectable		 1hxbA-4fwtA:
6.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fxd DNA POLYMERASE ALPHA
CATALYTIC SUBUNIT A

(Saccharomyces
cerevisiae) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		3 ARG A 668
THR A 365
VAL A 362
 None
 0.93A 1hxbA-4fxdA:
undetectable		 1hxbA-4fxdA:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4grx AMINOTRANSFERASE

(Paracoccus
denitrificans) 		PF00202
(Aminotran_3) 		3 ARG A  48
THR A  34
VAL A  42
 None
 0.91A 1hxbA-4grxA:
undetectable		 1hxbA-4grxA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kna N-SUCCINYLGLUTAMATE
5-SEMIALDEHYDE
DEHYDROGENASE

(Burkholderia
thailandensis) 		PF00171
(Aldedh) 		3 ARG A  42
THR A   2
VAL A  11
 None
 0.89A 1hxbA-4knaA:
undetectable		 1hxbA-4knaA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kqn D-HYDANTOINASE

(Bacillus sp.
AR9) 		PF01979
(Amidohydro_1) 		3 ARG A 455
THR A  59
VAL A  90
 ARG  A 455 ( 0.6A)
THR  A  59 ( 0.8A)
VAL  A  90 ( 0.6A)
 0.94A 1hxbA-4kqnA:
undetectable		 1hxbA-4kqnA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l4w ESPG3

(Mycolicibacterium
smegmatis) 		PF14011
(ESX-1_EspG) 		3 ARG A  85
THR A 210
VAL A 198
 None
 1.01A 1hxbA-4l4wA:
undetectable		 1hxbA-4l4wA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mfz DBV8 PROTEIN

(Nonomuraea
gerenzanensis) 		no annotation 3 ARG A  42
THR A  62
VAL A  59
 None
 0.87A 1hxbA-4mfzA:
undetectable		 1hxbA-4mfzA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mnd CTP
L-MYO-INOSITOL-1-PHO
SPHATE
CYTIDYLYLTRANSFERASE
/CDP-L-MYO-INOSITOL
MYO-INOSITOLPHOSPHOT
RANSFERASE

(Archaeoglobus
fulgidus) 		PF01066
(CDP-OH_P_transf)
PF12804
(NTP_transf_3) 		3 ARG A 446
THR A 417
VAL A 414
 None
 0.89A 1hxbA-4mndA:
undetectable		 1hxbA-4mndA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oe5 DELTA-1-PYRROLINE-5-
CARBOXYLATE
DEHYDROGENASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00171
(Aldedh) 		3 ARG A 367
THR A 336
VAL A 333
 None
 0.63A 1hxbA-4oe5A:
undetectable		 1hxbA-4oe5A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p0s CROSSOVER JUNCTION
ENDONUCLEASE MUS81

(Homo sapiens) 		PF02732
(ERCC4) 		3 ARG A 401
THR A 391
VAL A 388
 None
 0.75A 1hxbA-4p0sA:
undetectable		 1hxbA-4p0sA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s2t PROTEIN APP-1

(Caenorhabditis
elegans) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N)
PF16188
(Peptidase_M24_C)
PF16189
(Creatinase_N_2) 		3 ARG P 427
THR P 423
VAL P 425
 None
 0.93A 1hxbA-4s2tP:
undetectable		 1hxbA-4s2tP:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x8f RIBOKINASE

(Vibrio cholerae) 		PF00294
(PfkB) 		3 ARG A  71
THR A  92
VAL A  61
 None
 0.89A 1hxbA-4x8fA:
undetectable		 1hxbA-4x8fA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgi GLUTAMATE
DEHYDROGENASE

(Burkholderia
thailandensis) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		3 ARG A  77
THR A 167
VAL A  91
 None
 0.87A 1hxbA-4xgiA:
undetectable		 1hxbA-4xgiA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b16 RIBONUCLEASE
3,DROSHA,RIBONUCLEAS
E
3,DROSHA,RIBONUCLEAS
E 3

(Homo sapiens) 		PF00035
(dsrm)
PF00636
(Ribonuclease_3)
PF14622
(Ribonucleas_3_3) 		3 ARG A 684
THR A 416
VAL A 696
 None
 0.98A 1hxbA-5b16A:
undetectable		 1hxbA-5b16A:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bov PUTATIVE EPOXIDE
HYDROLASE PROTEIN

(Klebsiella
pneumoniae) 		PF00561
(Abhydrolase_1) 		3 ARG A 206
THR A 247
VAL A 244
 None
 0.93A 1hxbA-5bovA:
undetectable		 1hxbA-5bovA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cx8 LIPOPROTEIN RAGB

(Porphyromonas
gingivalis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		3 ARG A 212
THR A 127
VAL A 124
 None
 0.61A 1hxbA-5cx8A:
undetectable		 1hxbA-5cx8A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dlb CHAPERONE ESPG3

(Mycobacterium
marinum) 		PF14011
(ESX-1_EspG) 		3 ARG A  87
THR A 229
VAL A 217
 None
 0.87A 1hxbA-5dlbA:
undetectable		 1hxbA-5dlbA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eyb DNA-BINDING PROTEIN
REB1

(Schizosaccharomyces
pombe) 		PF00249
(Myb_DNA-binding) 		3 ARG A 232
THR A 246
VAL A 243
 None
 0.86A 1hxbA-5eybA:
undetectable		 1hxbA-5eybA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j5t MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE KINASE
3

(Homo sapiens) 		PF00069
(Pkinase) 		3 ARG A 135
THR A  26
VAL A 157
 None
 0.94A 1hxbA-5j5tA:
undetectable		 1hxbA-5j5tA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jqk PEPTIDASE, PUTATIVE

(Plasmodium
falciparum) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N)
PF16188
(Peptidase_M24_C)
PF16189
(Creatinase_N_2) 		3 ARG A 584
THR A 580
VAL A 582
 None
 0.95A 1hxbA-5jqkA:
undetectable		 1hxbA-5jqkA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jta NEUTRAL TREHALASE

(Saccharomyces
cerevisiae) 		no annotation 3 ARG A 725
THR A 662
VAL A 182
 None
 0.89A 1hxbA-5jtaA:
undetectable		 1hxbA-5jtaA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kei 2,3-DIHYDROXYBENZOAT
E-AMP LIGASE

(Mycolicibacterium
smegmatis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		3 ARG A 387
THR A 542
VAL A 544
 None
 0.89A 1hxbA-5keiA:
undetectable		 1hxbA-5keiA:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ndx GLYCOSYL HYDROLASE

(Rhizobium
leguminosarum) 		no annotation 3 ARG A 542
THR A 355
VAL A 352
 None
 0.75A 1hxbA-5ndxA:
undetectable		 1hxbA-5ndxA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oe5 ANTHRANILATE--COA
LIGASE

(Pseudomonas
aeruginosa) 		PF00501
(AMP-binding) 		3 ARG A 379
THR A 341
VAL A 335
 None
 0.96A 1hxbA-5oe5A:
undetectable		 1hxbA-5oe5A:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oen INTERFERON
REGULATORY FACTOR 9
SIGNAL TRANSDUCER
AND ACTIVATOR OF
TRANSCRIPTION

(Mus musculus) 		no annotation 3 ARG A 236
THR B 201
VAL B 171
 None
 0.76A 1hxbA-5oenA:
undetectable		 1hxbA-5oenA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5owj TRIGGER FACTOR

(Escherichia
coli) 		no annotation 3 ARG A 271
THR A 133
VAL A 132
 None
 1.01A 1hxbA-5owjA:
undetectable		 1hxbA-5owjA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u32 TRNA LIGASE

(Candida
albicans) 		no annotation 3 ARG A 494
THR A 410
VAL A 502
 None
 0.87A 1hxbA-5u32A:
undetectable		 1hxbA-5u32A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uuj ALKZ

(Streptomyces
sahachiroi) 		PF06224
(HTH_42) 		3 ARG A 177
THR A 184
VAL A 131
 None
 0.89A 1hxbA-5uujA:
undetectable		 1hxbA-5uujA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uuw INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Bacillus
anthracis) 		PF00478
(IMPDH) 		3 ARG A 440
THR A  34
VAL A  32
 None
 0.95A 1hxbA-5uuwA:
undetectable		 1hxbA-5uuwA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vbu CYTOCHROME P450
21-HYDROXYLASE

(Homo sapiens) 		PF00067
(p450) 		3 ARG A 234
THR A 201
VAL A 198
 3QZ  A 502 (-3.8A)
None
3QZ  A 502 (-4.6A)
 1.01A 1hxbA-5vbuA:
undetectable		 1hxbA-5vbuA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wmm NRPS

(Micromonospora
sp. ML1) 		no annotation 3 ARG A 392
THR A 311
VAL A 366
 None
 0.82A 1hxbA-5wmmA:
undetectable		 1hxbA-5wmmA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xkl ESX-3
SECRETION-ASSOCIATED
PROTEIN ESPG3

(Mycobacterium
tuberculosis) 		no annotation 3 ARG A  87
THR A 226
VAL A 214
 SO4  A 301 (-3.5A)
None
None
 0.89A 1hxbA-5xklA:
undetectable		 1hxbA-5xklA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xtd NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT 6

(Homo sapiens) 		PF05347
(Complex1_LYR) 		3 ARG E  60
THR E  46
VAL E  43
 None
 0.68A 1hxbA-5xtdE:
undetectable		 1hxbA-5xtdE:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y9d ACYL-COENZYME A
OXIDASE 1

(Yarrowia
lipolytica) 		no annotation 3 ARG A 617
THR A 624
VAL A 620
 None
 0.90A 1hxbA-5y9dA:
undetectable		 1hxbA-5y9dA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6a8l -

(-) 		no annotation 3 ARG A  84
THR A  38
VAL A  35
 None
 0.95A 1hxbA-6a8lA:
undetectable		 1hxbA-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c2j RNAP2

(Escherichia
virus N4) 		no annotation 3 ARG B  91
THR B 399
VAL B 100
 None
 0.93A 1hxbA-6c2jB:
undetectable		 1hxbA-6c2jB:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cet GATOR COMPLEX
PROTEIN NPRL3

(Homo sapiens) 		no annotation 3 ARG M 422
THR M 388
VAL M 385
 None
 0.96A 1hxbA-6cetM:
undetectable		 1hxbA-6cetM:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f0k FE-S-CLUSTER-CONTAIN
ING HYDROGENASE

(Rhodothermus
marinus) 		no annotation 3 ARG B 954
THR B 947
VAL B 950
 None
 0.89A 1hxbA-6f0kB:
0.9		 1hxbA-6f0kB:
22.64