SIMILAR PATTERNS OF AMINO ACIDS FOR 1H7X_A_URFA1033_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bjn | PHOSPHOSERINEAMINOTRANSFERASE (Escherichiacoli) |
PF00266(Aminotran_5) | 4 | ASN A 199ILE A 338SER A 296ASN A 151 | LLP A 198 ( 4.3A)NoneNoneNone | 1.25A | 1h7xA-1bjnA:undetectable | 1h7xA-1bjnA:16.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f26 | NITRIC OXIDEREDUCTASE (Fusariumoxysporum) |
PF00067(p450) | 4 | ASN A 176ASN A 241SER A 150ASN A 171 | None | 1.17A | 1h7xA-1f26A:undetectable | 1h7xA-1f26A:17.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f76 | DIHYDROOROTATEDEHYDROGENASE(QUINONE) (Escherichiacoli) |
PF01180(DHO_dh) | 4 | ASN A 111ASN A 172ASN A 246THR A 247 | ORO A1338 ( 2.9A)ORO A1338 ( 3.2A)ORO A1338 (-3.0A)ORO A1338 ( 2.6A) | 0.16A | 1h7xA-1f76A:29.5 | 1h7xA-1f76A:16.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g8k | ARSENITE OXIDASE (Alcaligenesfaecalis) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 4 | ASN A 464ILE A 194ASN A 201THR A 789 | None | 1.06A | 1h7xA-1g8kA:undetectable | 1h7xA-1g8kA:21.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1h7w | DIHYDROPYRIMIDINEDEHYDROGENASE (Sus scrofa) |
PF01180(DHO_dh)PF07992(Pyr_redox_2)PF14691(Fer4_20)PF14697(Fer4_21) | 6 | ASN A 609ILE A 613ASN A 668SER A 670ASN A 736THR A 737 | FMN A1030 (-3.7A)NoneFMN A1030 (-4.0A)NoneFMN A1030 (-3.6A)FMN A1030 ( 4.4A) | 0.20A | 1h7xA-1h7wA:59.2 | 1h7xA-1h7wA:99.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m0v | PROTEIN-TYROSINEPHOSPHATASE YOPH (Yersiniapseudotuberculosis) |
PF09013(YopH_N) | 4 | ILE A 44SER A 51ASN A 34THR A 24 | None | 1.09A | 1h7xA-1m0vA:undetectable | 1h7xA-1m0vA:9.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o5t | TRYPTOPHANYL-TRNASYNTHETASE (Homo sapiens) |
PF00579(tRNA-synt_1b) | 4 | ILE A 254ASN A 250ASN A 291THR A 301 | None | 1.27A | 1h7xA-1o5tA:undetectable | 1h7xA-1o5tA:16.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rz2 | CONSERVEDHYPOTHETICAL PROTEINBA4783 (Bacillusanthracis) |
PF04203(Sortase) | 4 | ASN A 102ILE A 192ASN A 134ASN A 126 | None | 1.23A | 1h7xA-1rz2A:undetectable | 1h7xA-1rz2A:12.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sq1 | CHORISMATE SYNTHASE (Campylobacterjejuni) |
PF01264(Chorismate_synt) | 4 | ILE A 287ASN A 271SER A 273ASN A 282 | None | 0.95A | 1h7xA-1sq1A:undetectable | 1h7xA-1sq1A:16.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uuo | DIHYDROOROTATEDEHYDROGENASE (Rattus rattus) |
PF01180(DHO_dh) | 4 | ASN A 145ASN A 212ASN A 284THR A 285 | ORO A1399 ( 3.0A)FMN A1398 ( 3.0A)ORO A1399 ( 3.2A)ORO A1399 (-2.7A) | 0.66A | 1h7xA-1uuoA:31.0 | 1h7xA-1uuoA:17.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uvf | SERINE PROTEINASEINHIBITOR KAZAL TYPE5 (Homo sapiens) |
PF00050(Kazal_1) | 4 | ILE A 52SER A 2ASN A 43THR A 48 | None | 1.17A | 1h7xA-1uvfA:undetectable | 1h7xA-1uvfA:6.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w7c | LYSYL OXIDASE (Komagataellapastoris) |
PF01179(Cu_amine_oxid)PF02727(Cu_amine_oxidN2)PF09248(DUF1965) | 4 | ILE A 502SER A 526ASN A 391THR A 394 | TPQ A 478 ( 4.8A)NoneNoneNone | 1.03A | 1h7xA-1w7cA:undetectable | 1h7xA-1w7cA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z2o | INOSITOL1,3,4-TRISPHOSPHATE5/6-KINASE (Entamoebahistolytica) |
PF05770(Ins134_P3_kin) | 4 | ASN X 235ILE X 229ASN X 175THR X 193 | None | 0.97A | 1h7xA-1z2oX:undetectable | 1h7xA-1z2oX:14.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zb1 | BRO1 PROTEIN (Saccharomycescerevisiae) |
PF03097(BRO1) | 4 | ILE A 124ASN A 67ASN A 55THR A 13 | None | 1.27A | 1h7xA-1zb1A:undetectable | 1h7xA-1zb1A:16.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a8b | RECEPTOR-TYPETYROSINE-PROTEINPHOSPHATASE R (Homo sapiens) |
PF00102(Y_phosphatase) | 4 | ILE A 452ASN A 450SER A 430ASN A 427 | None | 1.27A | 1h7xA-2a8bA:undetectable | 1h7xA-2a8bA:14.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bv5 | TYROSINE-PROTEINPHOSPHATASE,NON-RECEPTOR TYPE 5 (Homo sapiens) |
PF00102(Y_phosphatase) | 4 | ILE A 335ASN A 333SER A 313ASN A 310 | None | 1.26A | 1h7xA-2bv5A:undetectable | 1h7xA-2bv5A:13.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ccm | CALEXCITIN (Doryteuthispealeii) |
no annotation | 4 | ASN A 183ILE A 14SER A 7ASN A 176 | None | 1.21A | 1h7xA-2ccmA:undetectable | 1h7xA-2ccmA:11.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fgy | CARBOXYSOME SHELLPOLYPEPTIDE (Halothiobacillusneapolitanus) |
PF08936(CsoSCA) | 4 | ASN A 59ILE A 185ASN A 375THR A 54 | None | 1.19A | 1h7xA-2fgyA:undetectable | 1h7xA-2fgyA:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iuj | LIPOXYGENASE L-5 (Glycine max) |
PF00305(Lipoxygenase)PF01477(PLAT) | 4 | ASN A 503ILE A 429ASN A 436THR A 442 | None | 1.27A | 1h7xA-2iujA:undetectable | 1h7xA-2iujA:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k24 | PUTATIVEUNCHARACTERIZEDPROTEIN TA0956 (Thermoplasmaacidophilum) |
PF11513(TA0956) | 4 | ASN A 71SER A 10ASN A 8THR A 18 | None | 1.12A | 1h7xA-2k24A:undetectable | 1h7xA-2k24A:7.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o4e | O-GLCNACASE NAGJ (Clostridiumperfringens) |
PF00963(Cohesin) | 4 | ASN A 71ILE A 95ASN A 138THR A 137 | None | 1.06A | 1h7xA-2o4eA:undetectable | 1h7xA-2o4eA:10.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oqz | SORTASE B (Bacillusanthracis) |
PF04203(Sortase) | 4 | ASN A 102ILE A 192ASN A 134ASN A 126 | CS4 A 233 ( 4.1A)NoneNoneNone | 1.21A | 1h7xA-2oqzA:undetectable | 1h7xA-2oqzA:11.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2plc | PHOSPHATIDYLINOSITOL-SPECIFICPHOSPHOLIPASE C (Listeriamonocytogenes) |
PF00388(PI-PLC-X) | 4 | ILE A 143SER A 176ASN A 178THR A 180 | None | 1.06A | 1h7xA-2plcA:undetectable | 1h7xA-2plcA:13.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2plc | PHOSPHATIDYLINOSITOL-SPECIFICPHOSPHOLIPASE C (Listeriamonocytogenes) |
PF00388(PI-PLC-X) | 4 | ILE A 289ASN A 292SER A 40THR A 265 | None | 1.26A | 1h7xA-2plcA:undetectable | 1h7xA-2plcA:13.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qg7 | ETHANOLAMINE KINASEPV091845 (Plasmodiumvivax) |
PF01633(Choline_kinase) | 4 | ASN A 122ILE A 350ASN A 301SER A 300 | SO4 A 600 (-3.5A)NoneNoneNone | 0.94A | 1h7xA-2qg7A:undetectable | 1h7xA-2qg7A:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wyh | ALPHA-MANNOSIDASE (Streptococcuspyogenes) |
PF01074(Glyco_hydro_38)PF07748(Glyco_hydro_38C)PF09261(Alpha-mann_mid) | 4 | ASN A 739ILE A 694SER A 99THR A 309 | None | 1.09A | 1h7xA-2wyhA:undetectable | 1h7xA-2wyhA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x7q | POSSIBLE THIAMINEBIOSYNTHESIS ENZYME (Candidaalbicans) |
PF09084(NMT1) | 4 | ASN A 52ILE A 46ASN A 72ASN A 74 | CA A1308 (-3.3A)NoneNoneNone | 1.25A | 1h7xA-2x7qA:undetectable | 1h7xA-2x7qA:14.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xdr | BETAINE ALDEHYDEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00171(Aldedh) | 4 | ASN A 465ILE A 158SER A 226THR A 469 | NoneTOE A1492 (-4.4A)NoneNone | 1.24A | 1h7xA-2xdrA:undetectable | 1h7xA-2xdrA:18.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yk0 | ERYTHROCYTE MEMBRANEPROTEIN 1 (Plasmodiumfalciparum) |
PF03011(PFEMP)PF05424(Duffy_binding)PF15447(NTS) | 4 | ASN A 160ILE A 86ASN A 148THR A 151 | None | 1.07A | 1h7xA-2yk0A:undetectable | 1h7xA-2yk0A:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yne | GLYCYLPEPTIDEN-TETRADECANOYLTRANSFERASE (Plasmodiumvivax) |
PF01233(NMT)PF02799(NMT_C) | 4 | ILE A 52ASN A 55ASN A 187THR A 183 | NoneNoneNHW A1000 (-4.3A)NHW A1000 (-3.7A) | 1.24A | 1h7xA-2yneA:undetectable | 1h7xA-2yneA:17.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aeh | HEMOGLOBIN-BINDINGPROTEASE HBPAUTOTRANSPORTER (Escherichiacoli) |
PF03797(Autotransporter) | 4 | ASN A1093ILE A1203SER A1223ASN A1207 | None | 1.22A | 1h7xA-3aehA:undetectable | 1h7xA-3aehA:15.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bfg | CLASS ABETA-LACTAMASE SED1 (Citrobactersedlakii) |
PF13354(Beta-lactamase2) | 4 | ASN A 136ASN A 170ASN A 104THR A 103 | NoneMER A 301 (-2.6A)MER A 301 ( 4.1A)None | 1.25A | 1h7xA-3bfgA:undetectable | 1h7xA-3bfgA:13.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cqf | THIOL-ACTIVATEDCYTOLYSIN (Bacillusanthracis) |
PF01289(Thiol_cytolysin)PF17440(Thiol_cytolys_C) | 4 | ASN A 383ILE A 55ASN A 52SER A 255 | None | 1.25A | 1h7xA-3cqfA:undetectable | 1h7xA-3cqfA:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3csk | PROBABLEDIPEPTIDYL-PEPTIDASE3 (Saccharomycescerevisiae) |
PF03571(Peptidase_M49) | 4 | ILE A 235SER A 299ASN A 211THR A 212 | None | 1.25A | 1h7xA-3cskA:undetectable | 1h7xA-3cskA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g7k | 3-METHYLITACONATEISOMERASE (Eubacteriumbarkeri) |
PF04303(PrpF) | 4 | ASN A 203ILE A 99ASN A 126THR A 129 | None | 1.21A | 1h7xA-3g7kA:undetectable | 1h7xA-3g7kA:17.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g85 | TRANSCRIPTIONALREGULATOR (LACIFAMILY) (Clostridiumacetobutylicum) |
PF13377(Peripla_BP_3) | 4 | ASN A 280ILE A 277ASN A 249ASN A 224 | None | 1.15A | 1h7xA-3g85A:undetectable | 1h7xA-3g85A:14.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i6r | DIHYDROOROTATEDEHYDROGENASEHOMOLOG,MITOCHONDRIAL (Plasmodiumfalciparum) |
PF01180(DHO_dh) | 4 | ASN A 274ASN A 342ASN A 458THR A 459 | ORO A1003 ( 3.1A)ORO A1003 ( 3.5A)ORO A1003 ( 3.0A)ORO A1003 (-2.6A) | 0.41A | 1h7xA-3i6rA:8.3 | 1h7xA-3i6rA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k0b | PREDICTEDN6-ADENINE-SPECIFICDNA METHYLASE (Listeriamonocytogenes) |
PF01170(UPF0020)PF02926(THUMP) | 4 | ILE A 45ASN A 49SER A 156THR A 9 | NoneNoneNoneGOL A 701 (-2.6A) | 1.00A | 1h7xA-3k0bA:3.8 | 1h7xA-3k0bA:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o4f | SPERMIDINE SYNTHASE (Escherichiacoli) |
PF01564(Spermine_synth)PF17284(Spermine_synt_N) | 4 | ILE A 163SER A 205ASN A 192THR A 232 | None | 1.15A | 1h7xA-3o4fA:3.5 | 1h7xA-3o4fA:14.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oix | DIHYDROOROTATEOXIDASEPUTATIVEDIHYDROOROTATEDEHYDROGENASE (Streptococcusmutans) |
PF01180(DHO_dh) | 4 | ASN A 69ASN A 128SER A 130ASN A 194 | FMN A 400 (-3.6A)FMN A 400 (-3.3A)NoneFMN A 400 (-3.4A) | 0.96A | 1h7xA-3oixA:16.3 | 1h7xA-3oixA:16.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qcw | NEUREXIN-1-ALPHA (Bos taurus) |
PF00008(EGF)PF02210(Laminin_G_2) | 4 | ASN A 440ILE A 656SER A 510THR A 429 | None | 1.05A | 1h7xA-3qcwA:undetectable | 1h7xA-3qcwA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r4c | HYDROLASE, HALOACIDDEHALOGENASE-LIKEHYDROLASE (Bacteroidesthetaiotaomicron) |
PF08282(Hydrolase_3) | 4 | ASN A 179ILE A 62ASN A 211THR A 169 | NoneNoneSO4 A 260 (-3.3A)SO4 A 262 (-3.8A) | 1.26A | 1h7xA-3r4cA:2.7 | 1h7xA-3r4cA:15.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rj9 | ALCOHOLDEHYDROGENASE (Scaptodrosophilalebanonensis) |
PF00106(adh_short) | 4 | ILE A 94ASN A 107SER A 154THR A 140 | None | 1.26A | 1h7xA-3rj9A:4.7 | 1h7xA-3rj9A:14.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rko | NADH-QUINONEOXIDOREDUCTASESUBUNIT N (Escherichiacoli) |
no annotation | 4 | ASN N 121ILE N 9SER N 51THR N 77 | None | 1.18A | 1h7xA-3rkoN:undetectable | 1h7xA-3rkoN:18.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3syj | ADHESION ANDPENETRATION PROTEINAUTOTRANSPORTER (Haemophilusinfluenzae) |
PF02395(Peptidase_S6)PF03212(Pertactin) | 4 | ASN A 99ILE A 93SER A 80ASN A 82 | None | 1.22A | 1h7xA-3syjA:undetectable | 1h7xA-3syjA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u0f | BETA-KETOACYLSYNTHASE (Brucellaabortus) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | ASN A 165ILE A 344SER A 346ASN A 294 | NoneNoneNone NA A 410 (-3.4A) | 0.98A | 1h7xA-3u0fA:undetectable | 1h7xA-3u0fA:17.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uxf | FIMBRIAL SUBUNITTYPE 1 (Actinomycesoris) |
no annotation | 4 | ILE A 324ASN A 326SER A 328THR A 148 | None | 1.13A | 1h7xA-3uxfA:undetectable | 1h7xA-3uxfA:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v5r | PROTEIN GAL3 (Saccharomycescerevisiae) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C)PF10509(GalKase_gal_bdg) | 4 | ILE A 438ASN A 441SER A 436THR A 466 | None | 1.16A | 1h7xA-3v5rA:undetectable | 1h7xA-3v5rA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vil | BETA-GLUCOSIDASE (Neotermeskoshunensis) |
PF00232(Glyco_hydro_1) | 4 | ILE A 400ASN A 335ASN A 192THR A 145 | NoneSA0 A 507 ( 4.9A)SA0 A 507 (-3.4A)None | 1.24A | 1h7xA-3vilA:6.4 | 1h7xA-3vilA:18.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vil | BETA-GLUCOSIDASE (Neotermeskoshunensis) |
PF00232(Glyco_hydro_1) | 4 | ILE A 400ASN A 335SER A 251ASN A 192 | NoneSA0 A 507 ( 4.9A)NoneSA0 A 507 (-3.4A) | 1.24A | 1h7xA-3vilA:6.4 | 1h7xA-3vilA:18.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wel | ALPHA-GLUCOSIDASE (Beta vulgaris) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF16863(NtCtMGAM_N) | 4 | ILE A 286ASN A 270ASN A 522THR A 519 | NoneGOL A1010 ( 4.0A)GOL A1010 (-3.0A)None | 1.17A | 1h7xA-3welA:7.3 | 1h7xA-3welA:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zcw | KINESIN-LIKE PROTEINKIF11 (Homo sapiens) |
PF00225(Kinesin) | 4 | ASN A 190ILE A 319ASN A 262ASN A 98 | None | 1.00A | 1h7xA-3zcwA:undetectable | 1h7xA-3zcwA:17.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a5q | CHI1 (Yersiniaentomophaga) |
PF00704(Glyco_hydro_18) | 4 | ASN A 23ILE A 168ASN A 169SER A 96 | None | 0.90A | 1h7xA-4a5qA:10.8 | 1h7xA-4a5qA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4akx | EXOU (Pseudomonasaeruginosa) |
PF01734(Patatin) | 4 | ASN B 360ASN B 371SER B 106ASN B 369 | None | 1.16A | 1h7xA-4akxB:2.3 | 1h7xA-4akxB:23.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4az7 | BETA-N-ACETYLHEXOSAMINIDASE (Streptococcuspneumoniae) |
PF00728(Glyco_hydro_20) | 4 | ASN A 225SER A 437ASN A 356THR A 291 | LOG A1614 ( 4.2A)NoneNoneNone | 1.24A | 1h7xA-4az7A:5.1 | 1h7xA-4az7A:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c4v | OUTER MEMBRANEPROTEIN ASSEMBLYFACTOR BAMA (Escherichiacoli) |
PF01103(Bac_surface_Ag)PF07244(POTRA) | 4 | ASN A 606ASN A 506SER A 508THR A 567 | None | 1.04A | 1h7xA-4c4vA:undetectable | 1h7xA-4c4vA:17.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fys | AMINOPEPTIDASE N (Homo sapiens) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 4 | ASN A 516ILE A 401ASN A 405SER A 456 | None | 1.15A | 1h7xA-4fysA:undetectable | 1h7xA-4fysA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ga4 | PUTATIVE THYMIDINEPHOSPHORYLASE (Thermococcuskodakarensis) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N)PF07831(PYNP_C) | 4 | ILE A 281SER A 165ASN A 172THR A 174 | NonePO4 A 601 (-4.6A)NoneNone | 1.00A | 1h7xA-4ga4A:3.3 | 1h7xA-4ga4A:19.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ga6 | PUTATIVE THYMIDINEPHOSPHORYLASE (Thermococcuskodakarensis) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N)PF07831(PYNP_C) | 4 | ILE A 281SER A 165ASN A 172THR A 174 | NoneSO4 A 602 ( 4.4A)NoneNone | 1.00A | 1h7xA-4ga6A:4.3 | 1h7xA-4ga6A:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hi7 | GI20122 (Drosophilamojavensis) |
PF00043(GST_C)PF13417(GST_N_3) | 4 | ILE A 65ASN A 64ASN A 50THR A 54 | NoneNoneNoneGSH A 301 (-4.2A) | 1.16A | 1h7xA-4hi7A:2.2 | 1h7xA-4hi7A:12.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ieg | RNA-DEPENDENT RNAPOLYMERASE P2 (Pseudomonasphage phi12) |
no annotation | 4 | ASN A 246ASN A 544ASN A 200THR A 192 | None | 1.24A | 1h7xA-4iegA:undetectable | 1h7xA-4iegA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j8z | SPECKLE-TYPE POZPROTEIN (Homo sapiens) |
PF00651(BTB) | 4 | ILE A 305ASN A 301SER A 298THR A 335 | None | 1.26A | 1h7xA-4j8zA:undetectable | 1h7xA-4j8zA:12.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kr9 | PROBABLE TRNASULFURTRANSFERASE (Thermotogamaritima) |
PF02568(ThiI)PF02926(THUMP) | 4 | ILE A 360SER A 302ASN A 299THR A 296 | None | 1.06A | 1h7xA-4kr9A:2.6 | 1h7xA-4kr9A:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nsx | U3 SMALL NUCLEOLARRNA-ASSOCIATEDPROTEIN 21 (Saccharomycescerevisiae) |
PF00400(WD40)PF12894(ANAPC4_WD40) | 4 | ASN A 135ILE A 162ASN A 187THR A 184 | None | 1.03A | 1h7xA-4nsxA:undetectable | 1h7xA-4nsxA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p0d | TRYPSIN-RESISTANTSURFACE T6 PROTEIN (Streptococcuspyogenes) |
PF16569(GramPos_pilinBB) | 4 | ILE A 97ASN A 98ASN A 318THR A 132 | None | 1.17A | 1h7xA-4p0dA:undetectable | 1h7xA-4p0dA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r27 | GLYCOSIDE HYDROLASE (Microbacteriumsp. Gsoil167) |
PF00232(Glyco_hydro_1) | 4 | ASN A 171ILE A 289ASN A 253ASN A 174 | None | 1.14A | 1h7xA-4r27A:7.8 | 1h7xA-4r27A:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ry9 | PERIPLASMIC BINDINGPROTEIN/LACITRANSCRIPTIONALREGULATOR (Verminephrobactereiseniae) |
PF13407(Peripla_BP_4) | 4 | ASN A 171ASN A 280SER A 138ASN A 140 | TLZ A 401 (-3.0A)TLZ A 401 (-3.7A)NoneNone | 1.27A | 1h7xA-4ry9A:4.2 | 1h7xA-4ry9A:16.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4trg | SIDC (Legionellapneumophila) |
no annotation | 4 | ILE A 150ASN A 458SER A 154ASN A 156 | None | 1.11A | 1h7xA-4trgA:undetectable | 1h7xA-4trgA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tvc | DEXTRANSUCRASE (Leuconostocmesenteroides) |
PF02324(Glyco_hydro_70) | 4 | ASN A2543ILE A2372SER A2374THR A2499 | None | 1.17A | 1h7xA-4tvcA:3.2 | 1h7xA-4tvcA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4twb | RIBOSE-PHOSPHATEPYROPHOSPHOKINASE (Sulfolobussolfataricus) |
PF00156(Pribosyltran)PF13793(Pribosyltran_N) | 4 | ILE A 85SER A 284ASN A 269THR A 268 | None | 1.15A | 1h7xA-4twbA:2.5 | 1h7xA-4twbA:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u5a | SPOROZOITE MICRONEMEPROTEIN ESSENTIALFOR CELL TRAVERSAL (Plasmodiumberghei) |
no annotation | 4 | ASN A 119ILE A 124ASN A 125SER A 126 | None | 1.16A | 1h7xA-4u5aA:undetectable | 1h7xA-4u5aA:11.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wzb | NITROGENASEMOLYBDENUM-IRONPROTEIN ALPHA CHAIN (Azotobactervinelandii) |
PF00148(Oxidored_nitro) | 4 | ILE A 47ASN A 384SER A 42THR A 390 | None | 1.20A | 1h7xA-4wzbA:undetectable | 1h7xA-4wzbA:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xk1 | PHOSPHOSERINEAMINOTRANSFERASE (Pseudomonasaeruginosa) |
PF00266(Aminotran_5) | 4 | ASN A 198ILE A 337SER A 295ASN A 151 | LLP A 197 ( 4.2A)NoneNoneNone | 1.20A | 1h7xA-4xk1A:undetectable | 1h7xA-4xk1A:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xq6 | DIHYDROOROTATEDEHYDROGENASE(QUINONE) (Mycobacteriumtuberculosis) |
PF01180(DHO_dh) | 4 | ASN A 115ASN A 176ASN A 241THR A 242 | FMN A 401 ( 3.5A)FMN A 401 (-3.4A)FMN A 401 (-3.6A) CL A 403 (-3.1A) | 0.75A | 1h7xA-4xq6A:32.4 | 1h7xA-4xq6A:16.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zfm | PUTATIVE6-PHOSPHO-BETA-GALACTOBIOSIDASE (Geobacillusstearothermophilus) |
PF00232(Glyco_hydro_1) | 4 | ASN A 299SER A 224ASN A 169THR A 121 | None | 1.12A | 1h7xA-4zfmA:10.7 | 1h7xA-4zfmA:18.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zkt | BONTOXILYSIN A (Clostridiumbotulinum) |
PF01742(Peptidase_M27)PF07951(Toxin_R_bind_C)PF07952(Toxin_trans)PF07953(Toxin_R_bind_N) | 4 | ILE A 847SER A 851ASN A 854THR A 865 | None | 1.13A | 1h7xA-4zktA:undetectable | 1h7xA-4zktA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zud | CHIMERA PROTEIN OFSOLUBLE CYTOCHROMEB562 AND TYPE-1ANGIOTENSIN IIRECEPTOR (Escherichiacoli;Homo sapiens) |
PF00001(7tm_1)PF07361(Cytochrom_B562) | 4 | ASN A 46ILE A 245SER A 115ASN A 111 | None | 1.09A | 1h7xA-4zudA:undetectable | 1h7xA-4zudA:17.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zxk | SIALIDASE A (Streptococcuspneumoniae) |
PF02973(Sialidase) | 4 | ILE A 269ASN A 169SER A 172THR A 278 | None | 1.25A | 1h7xA-4zxkA:undetectable | 1h7xA-4zxkA:11.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b47 | 2-OXOACID--FERREDOXIN OXIDOREDUCTASEALPHA SUBUNIT (Sulfurisphaeratokodaii) |
PF01558(POR)PF01855(POR_N)PF17147(PFOR_II) | 4 | ASN A 37ILE A 602ASN A 572SER A 522 | None | 1.20A | 1h7xA-5b47A:2.1 | 1h7xA-5b47A:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fmv | RECEPTOR-TYPETYROSINE-PROTEINPHOSPHATASE C (Homo sapiens) |
PF00041(fn3)PF12567(CD45) | 4 | ASN A 468ILE A 462ASN A 434THR A 421 | NAG A1578 (-1.9A)NoneNAG A1578 (-4.3A)NAG A1578 (-3.0A) | 1.23A | 1h7xA-5fmvA:undetectable | 1h7xA-5fmvA:14.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fww | KREMEN PROTEIN 1 (Homo sapiens) |
PF00051(Kringle)PF00431(CUB)PF01822(WSC) | 4 | ASN B 119ILE B 111SER B 92ASN B 187 | None | 1.18A | 1h7xA-5fwwB:undetectable | 1h7xA-5fwwB:14.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gpd | STEROL REGULATORYELEMENT-BINDINGPROTEIN 1 (Schizosaccharomycespombe) |
PF09427(DUF2014) | 4 | ILE A 785ASN A 786SER A 788THR A 827 | None | 0.98A | 1h7xA-5gpdA:undetectable | 1h7xA-5gpdA:13.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5imt | INTERMEDILYSIN (Streptococcusintermedius) |
PF01289(Thiol_cytolysin)PF17440(Thiol_cytolys_C) | 4 | ASN A 397ILE A 68ASN A 65SER A 269 | None | 1.16A | 1h7xA-5imtA:undetectable | 1h7xA-5imtA:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5imw | INTERMEDILYSIN (Streptococcusintermedius) |
PF01289(Thiol_cytolysin)PF17440(Thiol_cytolys_C) | 4 | ASN A 397ILE A 68ASN A 65SER A 269 | None | 1.21A | 1h7xA-5imwA:undetectable | 1h7xA-5imwA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5je8 | 3-HYDROXYISOBUTYRATEDEHYDROGENASE (Bacillus cereus) |
PF03446(NAD_binding_2)PF14833(NAD_binding_11) | 4 | ILE A 179ASN A 175SER A 122THR A 96 | EPE A 402 (-4.8A)NoneEPE A 402 (-3.4A)NAD A 401 (-4.0A) | 1.26A | 1h7xA-5je8A:undetectable | 1h7xA-5je8A:17.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jxl | FLAGELLAR HOOKPROTEIN FLGE (Campylobacterjejuni) |
PF00460(Flg_bb_rod)PF06429(Flg_bbr_C)PF07196(Flagellin_IN)PF07559(FlaE) | 4 | ASN A 779ASN A 23ASN A 27THR A 30 | None | 1.05A | 1h7xA-5jxlA:undetectable | 1h7xA-5jxlA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kbp | GLYCOSYL HYDROLASE,FAMILY 38 (Enterococcusfaecalis) |
PF01074(Glyco_hydro_38)PF07748(Glyco_hydro_38C)PF09261(Alpha-mann_mid) | 4 | ASN A 733ILE A 689SER A 99THR A 308 | None | 1.14A | 1h7xA-5kbpA:1.7 | 1h7xA-5kbpA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5klf | CARBOHYDRATE BINDINGMODULE E1 (unculturedbacterium) |
no annotation | 4 | ILE A 42ASN A 63SER A 50THR A 46 | None | 1.16A | 1h7xA-5klfA:undetectable | 1h7xA-5klfA:6.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ksw | DIHYDROOROTATEDEHYDROGENASE (Lactococcuslactis) |
PF01180(DHO_dh) | 4 | ASN A 132SER A 134ASN A 197THR A 198 | FMN A 401 (-3.3A)NoneFMN A 401 (-3.7A)FMN A 401 ( 4.7A) | 0.84A | 1h7xA-5kswA:36.1 | 1h7xA-5kswA:15.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mvd | DIHYDROOROTATEDEHYDROGENASE(QUINONE),MITOCHONDRIAL (Homo sapiens) |
PF01180(DHO_dh) | 4 | ASN A 145ASN A 212ASN A 284THR A 285 | ORO A 402 ( 3.1A)ORO A 402 ( 3.2A)ORO A 402 ( 2.9A)ORO A 402 ( 2.8A) | 0.34A | 1h7xA-5mvdA:30.3 | 1h7xA-5mvdA:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u47 | PENICILLIN BINDINGPROTEIN 2X (Streptococcusthermophilus) |
PF00905(Transpeptidase)PF03717(PBP_dimer)PF03793(PASTA) | 4 | ILE A 684SER A 677ASN A 710THR A 707 | None | 1.13A | 1h7xA-5u47A:undetectable | 1h7xA-5u47A:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uld | TRANSPORTER, NADCFAMILY (Vibrio cholerae) |
PF00939(Na_sulph_symp) | 4 | ASN A 378ILE A 407ASN A 203THR A 200 | CIT A 503 ( 3.3A)NoneNoneCIT A 503 (-3.6A) | 1.22A | 1h7xA-5uldA:undetectable | 1h7xA-5uldA:17.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y2w | RUBISCO OPERONTRANSCRIPTIONALREGULATOR (Synechocystissp. PCC 6803) |
no annotation | 4 | ASN A 225ASN A 164SER A 148THR A 201 | NonePGA A 401 (-3.1A)PGA A 401 (-3.5A)PGA A 401 (-3.6A) | 1.14A | 1h7xA-5y2wA:undetectable | 1h7xA-5y2wA:5.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b8s | DIHYDROOROTATEDEHYDROGENASE(QUINONE) (Helicobacterpylori) |
no annotation | 4 | ASN A 116ASN A 178ASN A 243THR A 244 | FMN A 401 (-3.6A)FMN A 401 (-2.9A)FMN A 401 (-3.6A)FMN A 401 ( 4.8A) | 0.53A | 1h7xA-6b8sA:30.4 | 1h7xA-6b8sA:8.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ci9 | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE (Mycolicibacteriumsmegmatis) |
no annotation | 4 | ILE A 94ASN A 115SER A 160THR A 145 | NoneNoneNoneF3V A 302 (-3.9A) | 1.19A | 1h7xA-6ci9A:5.4 | 1h7xA-6ci9A:6.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cp0 | - (-) |
no annotation | 4 | ILE A 345SER A 438ASN A 43THR A 44 | None | 1.19A | 1h7xA-6cp0A:undetectable | 1h7xA-6cp0A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6czx | PHOSPHOSERINEAMINOTRANSFERASE 1,CHLOROPLASTIC (Arabidopsisthaliana) |
no annotation | 4 | ASN A 266ILE A 406SER A 364ASN A 219 | LLP A 265 ( 4.9A)NoneNoneNone | 1.25A | 1h7xA-6czxA:undetectable | 1h7xA-6czxA:6.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dde | MU-TYPE OPIOIDRECEPTOR (Mus musculus) |
no annotation | 4 | ASN R 191ILE R 186ASN R 183THR R 160 | None | 1.17A | 1h7xA-6ddeR:undetectable | 1h7xA-6ddeR:5.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ejj | WLAC PROTEIN (Campylobacterjejuni) |
no annotation | 4 | ASN A 106ILE A 37SER A 86THR A 111 | None | 1.06A | 1h7xA-6ejjA:2.2 | 1h7xA-6ejjA:6.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ek6 | LYSINE-SPECIFICDEMETHYLASE5B,LYSINE-SPECIFICDEMETHYLASE 5B (Homo sapiens) |
no annotation | 4 | ASN A 509ILE A 500SER A 505ASN A 601 | 90V A 804 ( 4.6A)DMS A 805 (-4.9A)None90V A 804 (-3.8A) | 1.05A | 1h7xA-6ek6A:undetectable | 1h7xA-6ek6A:6.26 |