SIMILAR PATTERNS OF AMINO ACIDS FOR 1H4O_H_BEZH1162
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1h4o | PEROXIREDOXIN 5 (Homo sapiens) |
PF08534(Redoxin) | 9 | PRO A 40THR A 44PRO A 45GLY A 46CYH A 47LEU A 116PHE A 120ARG A 127THR A 147 | BEZ A1162 (-4.5A)BEZ A1162 (-4.0A)BEZ A1162 (-3.7A)BEZ A1162 (-3.1A)BEZ A1162 (-3.3A)NoneNoneBEZ A1162 (-3.7A)BEZ A1162 ( 4.0A) | 0.25A | 1h4oH-1h4oA:34.8 | 1h4oH-1h4oA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1nm3 | PROTEIN HI0572 (Haemophilusinfluenzae) |
PF00462(Glutaredoxin)PF08534(Redoxin) | 7 | PRO A 42THR A 46PRO A 47CYH A 49LEU A 118PHE A 120ARG A 126 | None | 0.84A | 1h4oH-1nm3A:24.3 | 1h4oH-1nm3A:32.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1psq | PROBABLE THIOLPEROXIDASE (Streptococcuspneumoniae) |
PF08534(Redoxin) | 5 | PRO A 51THR A 55CYH A 58LEU A 5ARG A 127 | None | 1.10A | 1h4oH-1psqA:19.4 | 1h4oH-1psqA:25.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qd1 | FORMIMINOTRANSFERASE-CYCLODEAMINASE (Sus scrofa) |
PF02971(FTCD)PF07837(FTCD_N) | 5 | THR A 30PRO A 31GLY A 32CYH A 33LEU A 63 | None | 0.97A | 1h4oH-1qd1A:0.1 | 1h4oH-1qd1A:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rqg | METHIONYL-TRNASYNTHETASE (Pyrococcusabyssi) |
PF08264(Anticodon_1)PF09334(tRNA-synt_1g) | 5 | PRO A 11PRO A 16GLY A 15PHE A 82THR A 49 | None | 1.39A | 1h4oH-1rqgA:0.0 | 1h4oH-1rqgA:14.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tkl | COPROPORPHYRINOGENIII OXIDASE (Saccharomycescerevisiae) |
PF01218(Coprogen_oxidas) | 5 | THR A 283PRO A 284GLY A 285LEU A 78ARG A 46 | None | 1.25A | 1h4oH-1tklA:0.5 | 1h4oH-1tklA:20.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tp9 | PEROXIREDOXIN (Populustrichocarpa) |
PF08534(Redoxin) | 5 | PRO A 44THR A 48PRO A 49CYH A 51ARG A 129 | NoneSO4 A1248 ( 4.6A)SO4 A1248 (-3.6A)NoneNone | 0.16A | 1h4oH-1tp9A:26.8 | 1h4oH-1tp9A:43.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tp9 | PEROXIREDOXIN (Populustrichocarpa) |
PF08534(Redoxin) | 5 | THR A 48PRO A 49CYH A 51LEU A 118ARG A 129 | SO4 A1248 ( 4.6A)SO4 A1248 (-3.6A)NoneNoneNone | 0.58A | 1h4oH-1tp9A:26.8 | 1h4oH-1tp9A:43.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a4v | PEROXIREDOXIN DOT5 (Saccharomycescerevisiae) |
PF00578(AhpC-TSA) | 5 | PRO A 100THR A 104PRO A 105GLY A 106ARG A 175 | None | 0.60A | 1h4oH-2a4vA:20.1 | 1h4oH-2a4vA:26.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qs8 | XAA-PRO DIPEPTIDASE (Alteromonasmacleodii) |
PF01979(Amidohydro_1) | 5 | PRO A 135THR A 102GLY A 106PHE A 72THR A 109 | None | 1.33A | 1h4oH-2qs8A:0.0 | 1h4oH-2qs8A:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vz9 | FATTY ACID SYNTHASE (Sus scrofa) |
PF00107(ADH_zinc_N)PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF08242(Methyltransf_12)PF08659(KR)PF14765(PS-DH)PF16197(KAsynt_C_assoc) | 5 | THR A1122PRO A1123GLY A1512PHE A1517THR A1232 | None | 1.32A | 1h4oH-2vz9A:undetectable | 1h4oH-2vz9A:6.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2wfc | PEROXIREDOXIN 5 (Arenicolamarina) |
PF08534(Redoxin) | 5 | THR A 71PRO A 72GLY A 73LEU A 141ARG A 152 | None | 0.57A | 1h4oH-2wfcA:31.3 | 1h4oH-2wfcA:64.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yzh | PROBABLE THIOLPEROXIDASE (Aquifexaeolicus) |
PF08534(Redoxin) | 6 | PRO A 54THR A 58PRO A 59CYH A 61LEU A 126ARG A 132 | None | 0.91A | 1h4oH-2yzhA:19.0 | 1h4oH-2yzhA:24.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yzh | PROBABLE THIOLPEROXIDASE (Aquifexaeolicus) |
PF08534(Redoxin) | 5 | THR A 58PRO A 59CYH A 61ARG A 132THR A 153 | None | 0.74A | 1h4oH-2yzhA:19.0 | 1h4oH-2yzhA:24.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a24 | ALPHA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
PF10566(Glyco_hydro_97)PF14508(GH97_N)PF14509(GH97_C) | 5 | PRO A 450THR A 447GLY A 465LEU A 212ARG A 492 | None | 1.48A | 1h4oH-3a24A:undetectable | 1h4oH-3a24A:13.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a5w | PROBABLEPEROXIREDOXIN (Aeropyrumpernix) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 5 | PRO A 43THR A 47PRO A 48CYH A 50ARG A 126 | None | 0.51A | 1h4oH-3a5wA:16.4 | 1h4oH-3a5wA:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bt3 | GLYOXALASE-RELATEDENZYME, ARAC TYPE (Lachnoclostridiumphytofermentans) |
no annotation | 5 | THR A 252GLY A 255CYH A 256PHE A 158THR A 148 | None | 1.09A | 1h4oH-3bt3A:undetectable | 1h4oH-3bt3A:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bzm | MENAQUINONE-SPECIFICISOCHORISMATESYNTHASE (Escherichiacoli) |
PF00425(Chorismate_bind) | 5 | PRO A 20THR A 22PRO A 23GLY A 24ARG A 26 | None | 1.28A | 1h4oH-3bzmA:undetectable | 1h4oH-3bzmA:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3drn | PEROXIREDOXIN,BACTERIOFERRITINCOMIGRATORY PROTEINHOMOLOG (Sulfolobussolfataricus) |
PF00578(AhpC-TSA) | 5 | PRO A 38THR A 42PRO A 43GLY A 44ARG A 112 | CIT A 500 (-3.6A)CIT A 500 (-2.9A)CIT A 500 (-3.6A)CIT A 500 (-2.9A)CIT A 500 (-3.7A) | 0.37A | 1h4oH-3drnA:19.5 | 1h4oH-3drnA:25.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hmu | AMINOTRANSFERASE,CLASS III (Ruegeriapomeroyi) |
PF00202(Aminotran_3) | 5 | PRO A 229THR A 270GLY A 266CYH A 265THR A 276 | None | 1.35A | 1h4oH-3hmuA:undetectable | 1h4oH-3hmuA:15.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ivr | PUTATIVELONG-CHAIN-FATTY-ACID COA LIGASE (Rhodopseudomonaspalustris) |
PF00501(AMP-binding) | 5 | THR A 215GLY A 310LEU A 281PHE A 256THR A 302 | NoneNoneGOL A 512 (-4.7A)NoneGOL A 512 (-4.7A) | 1.42A | 1h4oH-3ivrA:undetectable | 1h4oH-3ivrA:18.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ixr | BACTERIOFERRITINCOMIGRATORY PROTEIN (Xylellafastidiosa) |
PF00578(AhpC-TSA) | 5 | PRO A 40THR A 44PRO A 45GLY A 46ARG A 122 | None | 0.45A | 1h4oH-3ixrA:19.0 | 1h4oH-3ixrA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jxa | CONTACTIN 4 (Mus musculus) |
PF07679(I-set)PF13927(Ig_3) | 5 | PRO A 208PRO A 146GLY A 145LEU A 206ARG A 129 | None | 1.45A | 1h4oH-3jxaA:undetectable | 1h4oH-3jxaA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oep | PUTATIVEUNCHARACTERIZEDPROTEIN TTHA0988 (Thermusthermophilus) |
PF02626(CT_A_B)PF02682(CT_C_D) | 5 | PRO A 186PRO A 121GLY A 122LEU A 346PHE A 345 | None | 1.35A | 1h4oH-3oepA:undetectable | 1h4oH-3oepA:17.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p7x | PROBABLE THIOLPEROXIDASE (Staphylococcusaureus) |
PF08534(Redoxin) | 5 | PRO A 53THR A 57CYH A 60LEU A 123ARG A 128 | None | 0.86A | 1h4oH-3p7xA:18.7 | 1h4oH-3p7xA:26.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tb2 | 1-CYS PEROXIREDOXIN (Plasmodiumyoelii) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 5 | PRO A 40THR A 44PRO A 45CYH A 47ARG A 129 | GOL A 223 (-4.3A)GOL A 223 ( 4.3A)GOL A 223 (-3.6A)GOL A 223 (-4.4A)GOL A 223 (-4.1A) | 0.55A | 1h4oH-3tb2A:17.6 | 1h4oH-3tb2A:20.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3uma | HYPOTHETICALPEROXIREDOXINPROTEIN (Sinorhizobiummeliloti) |
PF08534(Redoxin) | 5 | PRO A 42THR A 46PRO A 47CYH A 49ARG A 127 | None | 0.18A | 1h4oH-3umaA:27.5 | 1h4oH-3umaA:37.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zre | THIOL PEROXIDASE (Yersiniapseudotuberculosis) |
PF08534(Redoxin) | 5 | PRO A 54THR A 58CYH A 61LEU A 127ARG A 133 | None | 0.92A | 1h4oH-3zreA:18.2 | 1h4oH-3zreA:23.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4f82 | THIOREDOXINREDUCTASE (Burkholderiacenocepacia) |
PF08534(Redoxin) | 5 | PRO A 48THR A 52PRO A 53CYH A 55ARG A 133 | None | 0.13A | 1h4oH-4f82A:27.8 | 1h4oH-4f82A:42.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4f82 | THIOREDOXINREDUCTASE (Burkholderiacenocepacia) |
PF08534(Redoxin) | 5 | THR A 52PRO A 53CYH A 55LEU A 122ARG A 133 | None | 0.66A | 1h4oH-4f82A:27.8 | 1h4oH-4f82A:42.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lis | UDP-GLUCOSE4-EPIMERASE (Aspergillusnidulans) |
PF16363(GDP_Man_Dehyd) | 5 | THR A 153PRO A 152GLY A 151LEU A 320ARG A 137 | None | 1.33A | 1h4oH-4lisA:undetectable | 1h4oH-4lisA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oj5 | TAILSPIKE PROTEIN (Escherichiavirus CBA120) |
no annotation | 5 | PRO A 480PRO A 538GLY A 506PHE A 493THR A 503 | None | 1.42A | 1h4oH-4oj5A:undetectable | 1h4oH-4oj5A:12.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4piv | FATTY ACID SYNTHASE (Homo sapiens) |
PF08242(Methyltransf_12)PF08659(KR) | 5 | THR A1120PRO A1121GLY A1512PHE A1517THR A1230 | None | 1.33A | 1h4oH-4pivA:undetectable | 1h4oH-4pivA:13.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5enu | ALKYL HYDROPEROXIDEREDUCTASE/ THIOLSPECIFICANTIOXIDANT/ MALALLERGEN (Burkholderiaambifaria) |
PF00578(AhpC-TSA) | 6 | PRO A 37THR A 41PRO A 42GLY A 43CYH A 44ARG A 119 | None | 0.33A | 1h4oH-5enuA:19.0 | 1h4oH-5enuA:25.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5epf | PEROXIREDOXIN (Mycobacteriumtuberculosis) |
PF00578(AhpC-TSA) | 6 | PRO A 45THR A 49PRO A 50GLY A 51CYH A 52ARG A 124 | None | 0.89A | 1h4oH-5epfA:20.9 | 1h4oH-5epfA:28.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ipg | BACTERIOFERRITINCOMIGRATORY PROTEIN (Xanthomonascampestris) |
PF00578(AhpC-TSA) | 6 | PRO A 41THR A 45PRO A 46GLY A 47CYH A 48ARG A 123 | None | 0.66A | 1h4oH-5ipgA:18.2 | 1h4oH-5ipgA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jta | NEUTRAL TREHALASE (Saccharomycescerevisiae) |
no annotation | 5 | PRO A 271THR A 217PRO A 218GLY A 219ARG A 224 | None | 1.48A | 1h4oH-5jtaA:undetectable | 1h4oH-5jtaA:13.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5k1g | 1-CYS PEROXIREDOXIN (Vibriovulnificus) |
PF08534(Redoxin) | 5 | PRO A 41THR A 45PRO A 46PHE A 117ARG A 124 | None | 0.87A | 1h4oH-5k1gA:28.1 | 1h4oH-5k1gA:43.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfw | MONOVALENT CATION/H+ANTIPORTER SUBUNIT E (Pyrococcusfuriosus) |
no annotation | 5 | THR A 119PRO A 120GLY A 121LEU A 112THR A 124 | None | 1.30A | 1h4oH-6cfwA:undetectable | 1h4oH-6cfwA:undetectable |