SIMILAR PATTERNS OF AMINO ACIDS FOR 1H4O_G_BEZG1162_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1h4o | PEROXIREDOXIN 5 (Homo sapiens) |
PF08534(Redoxin) | 8 | PRO A 40THR A 44PRO A 45GLY A 46CYH A 47LEU A 116PHE A 120ARG A 127 | BEZ A1162 (-4.5A)BEZ A1162 (-4.0A)BEZ A1162 (-3.7A)BEZ A1162 (-3.1A)BEZ A1162 (-3.3A)NoneNoneBEZ A1162 (-3.7A) | 0.07A | 1h4oG-1h4oA:35.6 | 1h4oG-1h4oA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hr7 | MITOCHONDRIALPROCESSING PEPTIDASEALPHA SUBUNITMITOCHONDRIALPROCESSING PEPTIDASEBETA SUBUNIT (Saccharomycescerevisiae;Saccharomycescerevisiae) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C)PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 4 | PRO B 43THR A 35PRO A 36GLY A 37 | None | 0.76A | 1h4oG-1hr7B:undetectable | 1h4oG-1hr7B:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k8r | PROTEIN KINASE BYR2 (Schizosaccharomycespombe) |
PF14847(Ras_bdg_2) | 4 | THR B 94GLY B 89LEU B 143PHE B 75 | None | 0.72A | 1h4oG-1k8rB:undetectable | 1h4oG-1k8rB:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1miu | BREAST CANCER TYPE 2SUSCEPTIBILITYPROTEIN (Mus musculus) |
PF09103(BRCA-2_OB1)PF09104(BRCA-2_OB3)PF09121(Tower)PF09169(BRCA-2_helical) | 4 | THR A2528PRO A2529GLY A2530LEU A2575 | None | 0.60A | 1h4oG-1miuA:undetectable | 1h4oG-1miuA:13.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mje | BREAST CANCER 2 (Mus musculus) |
PF09103(BRCA-2_OB1)PF09104(BRCA-2_OB3)PF09121(Tower)PF09169(BRCA-2_helical) | 4 | THR A2528PRO A2529GLY A2530LEU A2575 | None | 0.72A | 1h4oG-1mjeA:undetectable | 1h4oG-1mjeA:13.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1nm3 | PROTEIN HI0572 (Haemophilusinfluenzae) |
PF00462(Glutaredoxin)PF08534(Redoxin) | 7 | PRO A 42THR A 46PRO A 47CYH A 49LEU A 118PHE A 120ARG A 126 | None | 0.79A | 1h4oG-1nm3A:24.1 | 1h4oG-1nm3A:32.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pc3 | PHOSPHATE-BINDINGPROTEIN 1 (Mycobacteriumtuberculosis) |
PF12849(PBP_like_2) | 4 | THR A 218PRO A 219GLY A 220CYH A 221 | None | 0.68A | 1h4oG-1pc3A:undetectable | 1h4oG-1pc3A:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1psq | PROBABLE THIOLPEROXIDASE (Streptococcuspneumoniae) |
PF08534(Redoxin) | 5 | PRO A 51THR A 55CYH A 58LEU A 5ARG A 127 | None | 1.05A | 1h4oG-1psqA:19.3 | 1h4oG-1psqA:25.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qd1 | FORMIMINOTRANSFERASE-CYCLODEAMINASE (Sus scrofa) |
PF02971(FTCD)PF07837(FTCD_N) | 4 | THR A 30PRO A 31GLY A 32CYH A 33 | None | 0.37A | 1h4oG-1qd1A:undetectable | 1h4oG-1qd1A:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qmv | PEROXIREDOXIN-2 (Homo sapiens) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 4 | PRO A 44THR A 48CYH A 51ARG A 127 | None | 0.53A | 1h4oG-1qmvA:18.4 | 1h4oG-1qmvA:27.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r9j | TRANSKETOLASE (Leishmaniamexicana) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 4 | THR A 106PRO A 107GLY A 108LEU A 87 | None | 0.56A | 1h4oG-1r9jA:undetectable | 1h4oG-1r9jA:13.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tp9 | PEROXIREDOXIN (Populustrichocarpa) |
PF08534(Redoxin) | 5 | PRO A 44THR A 48PRO A 49CYH A 51ARG A 129 | NoneSO4 A1248 ( 4.6A)SO4 A1248 (-3.6A)NoneNone | 0.17A | 1h4oG-1tp9A:26.7 | 1h4oG-1tp9A:43.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tp9 | PEROXIREDOXIN (Populustrichocarpa) |
PF08534(Redoxin) | 5 | THR A 48PRO A 49CYH A 51LEU A 118ARG A 129 | SO4 A1248 ( 4.6A)SO4 A1248 (-3.6A)NoneNoneNone | 0.60A | 1h4oG-1tp9A:26.7 | 1h4oG-1tp9A:43.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vs1 | 3-DEOXY-7-PHOSPHOHEPTULONATE SYNTHASE (Aeropyrumpernix) |
PF00793(DAHP_synth_1) | 4 | THR A 259PRO A 260GLY A 261ARG A 265 | None | 0.82A | 1h4oG-1vs1A:undetectable | 1h4oG-1vs1A:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xr5 | GENOME POLYPROTEIN (Rhinovirus B) |
PF00680(RdRP_1) | 4 | THR A 19PRO A 20LEU A 58PHE A 274 | None | 0.81A | 1h4oG-1xr5A:undetectable | 1h4oG-1xr5A:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xr6 | GENOME POLYPROTEIN (Rhinovirus A) |
PF00680(RdRP_1) | 4 | THR A 19PRO A 20LEU A 58PHE A 274 | None | 0.75A | 1h4oG-1xr6A:undetectable | 1h4oG-1xr6A:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y25 | PROBABLE THIOLPEROXIDASE (Mycobacteriumtuberculosis) |
PF08534(Redoxin) | 4 | PRO A 53THR A 57PRO A 58ARG A 130 | NoneACT A1200 (-3.6A)ACT A1200 (-3.6A)ACT A1200 (-3.1A) | 0.49A | 1h4oG-1y25A:19.0 | 1h4oG-1y25A:29.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z45 | GAL10 BIFUNCTIONALPROTEIN (Saccharomycescerevisiae) |
PF01263(Aldose_epim)PF16363(GDP_Man_Dehyd) | 5 | THR A 160PRO A 159GLY A 158LEU A 318ARG A 144 | NoneNoneNoneUPG A 704 (-3.9A)None | 1.27A | 1h4oG-1z45A:undetectable | 1h4oG-1z45A:13.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z60 | TFIIH BASALTRANSCRIPTION FACTORCOMPLEX P44 SUBUNIT (Homo sapiens) |
PF07975(C1_4) | 4 | PRO A 383GLY A 384CYH A 385PHE A 331 | None ZN A 2 ( 4.6A) ZN A 2 (-2.3A)None | 0.66A | 1h4oG-1z60A:undetectable | 1h4oG-1z60A:17.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zye | THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE (Bos taurus) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 4 | PRO A 40THR A 44CYH A 47ARG A 123 | None | 0.66A | 1h4oG-1zyeA:19.0 | 1h4oG-1zyeA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a4v | PEROXIREDOXIN DOT5 (Saccharomycescerevisiae) |
PF00578(AhpC-TSA) | 5 | PRO A 100THR A 104PRO A 105GLY A 106ARG A 175 | None | 0.62A | 1h4oG-2a4vA:20.0 | 1h4oG-2a4vA:26.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cx4 | BACTERIOFERRITINCOMIGRATORY PROTEIN (Aeropyrumpernix) |
PF00578(AhpC-TSA) | 4 | PRO A 42PRO A 47CYH A 49ARG A 122 | None | 0.36A | 1h4oG-2cx4A:21.0 | 1h4oG-2cx4A:28.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e6k | TRANSKETOLASE (Thermusthermophilus) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 4 | THR A 110PRO A 111GLY A 112LEU A 91 | None | 0.46A | 1h4oG-2e6kA:undetectable | 1h4oG-2e6kA:12.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f9h | PTS SYSTEM, IIACOMPONENT (Enterococcusfaecalis) |
PF03829(PTSIIA_gutA) | 4 | PRO A 111THR A 63GLY A 61LEU A 105 | None | 0.74A | 1h4oG-2f9hA:undetectable | 1h4oG-2f9hA:24.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h8x | XENOBIOTIC REDUCTASEA (Pseudomonasputida) |
PF00724(Oxidored_FMN) | 4 | THR A 67PRO A 68GLY A 69CYH A 70 | NoneSO4 A1506 ( 4.7A)NoneNone | 0.82A | 1h4oG-2h8xA:undetectable | 1h4oG-2h8xA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iun | AVIAN ADENOVIRUSCELO LONG FIBRE (Fowlaviadenovirus A) |
PF16812(AdHead_fibreRBD) | 4 | THR A 781PRO A 782LEU A 755PHE A 757 | None | 0.75A | 1h4oG-2iunA:undetectable | 1h4oG-2iunA:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jx1 | MYELIN TRANSCRIPTIONFACTOR 1 (Mus musculus) |
PF01530(zf-C2HC) | 4 | THR A 14PRO A 15GLY A 16CYH A 17 | None | 0.74A | 1h4oG-2jx1A:undetectable | 1h4oG-2jx1A:13.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kbe | ATP-DEPENDENT RNAHELICASE DBP5 (Saccharomycescerevisiae) |
PF00270(DEAD) | 4 | PRO A 198THR A 215PRO A 216GLY A 217 | None | 0.72A | 1h4oG-2kbeA:undetectable | 1h4oG-2kbeA:23.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lex | PROBABLE WRKYTRANSCRIPTION FACTOR4 (Arabidopsisthaliana) |
PF03106(WRKY) | 4 | THR A 436PRO A 437GLY A 438CYH A 439 | ZN A 500 (-3.5A)NoneNone ZN A 500 (-2.5A) | 0.66A | 1h4oG-2lexA:undetectable | 1h4oG-2lexA:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mf8 | MYELIN TRANSCRIPTIONFACTOR 1 (Mus musculus) |
PF01530(zf-C2HC) | 4 | THR A 804PRO A 805GLY A 806CYH A 807 | ZN A 901 (-4.0A)NoneNone ZN A 901 (-1.9A) | 0.82A | 1h4oG-2mf8A:undetectable | 1h4oG-2mf8A:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mf8 | MYELIN TRANSCRIPTIONFACTOR 1 (Mus musculus) |
PF01530(zf-C2HC) | 4 | THR A 848PRO A 849GLY A 850CYH A 851 | ZN A 902 (-3.2A)NoneNone ZN A 902 (-2.3A) | 0.83A | 1h4oG-2mf8A:undetectable | 1h4oG-2mf8A:19.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2pwj | MITOCHONDRIALPEROXIREDOXIN (Pisum sativum) |
PF08534(Redoxin) | 4 | PRO A 52THR A 56CYH A 59ARG A 137 | None | 0.51A | 1h4oG-2pwjA:26.3 | 1h4oG-2pwjA:35.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qz4 | PARAPLEGIN (Homo sapiens) |
PF00004(AAA) | 4 | PRO A 480PRO A 351GLY A 352CYH A 353 | NoneADP A 700 (-4.8A)ADP A 700 (-3.6A)None | 0.85A | 1h4oG-2qz4A:undetectable | 1h4oG-2qz4A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v41 | PEROXIREDOXIN 6. (Arenicolamarina) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 4 | PRO A 38THR A 42PRO A 43ARG A 128 | BEZ A1222 ( 4.6A)BEZ A1222 (-3.6A)BEZ A1222 (-3.2A)BEZ A1222 (-3.3A) | 0.48A | 1h4oG-2v41A:18.4 | 1h4oG-2v41A:25.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v6g | PROGESTERONE5-BETA-REDUCTASE (Digitalislanata) |
PF01370(Epimerase) | 4 | THR A 51PRO A 52GLY A 53LEU A 42 | None | 0.51A | 1h4oG-2v6gA:2.1 | 1h4oG-2v6gA:19.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vxo | GMP SYNTHASE[GLUTAMINE-HYDROLYZING] (Homo sapiens) |
PF00117(GATase)PF00958(GMP_synt_C)PF02540(NAD_synthase) | 4 | PRO A 650PRO A 687GLY A 688ARG A 638 | None | 0.74A | 1h4oG-2vxoA:undetectable | 1h4oG-2vxoA:17.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2wfc | PEROXIREDOXIN 5 (Arenicolamarina) |
PF08534(Redoxin) | 4 | PRO A 67THR A 71GLY A 73ARG A 152 | None | 0.60A | 1h4oG-2wfcA:31.6 | 1h4oG-2wfcA:64.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2wfc | PEROXIREDOXIN 5 (Arenicolamarina) |
PF08534(Redoxin) | 5 | THR A 71PRO A 72GLY A 73LEU A 141ARG A 152 | None | 0.56A | 1h4oG-2wfcA:31.6 | 1h4oG-2wfcA:64.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yzh | PROBABLE THIOLPEROXIDASE (Aquifexaeolicus) |
PF08534(Redoxin) | 6 | PRO A 54THR A 58PRO A 59CYH A 61LEU A 126ARG A 132 | None | 0.92A | 1h4oG-2yzhA:19.0 | 1h4oG-2yzhA:24.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a24 | ALPHA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
PF10566(Glyco_hydro_97)PF14508(GH97_N)PF14509(GH97_C) | 5 | PRO A 450THR A 447GLY A 465LEU A 212ARG A 492 | None | 1.47A | 1h4oG-3a24A:undetectable | 1h4oG-3a24A:13.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a5w | PROBABLEPEROXIREDOXIN (Aeropyrumpernix) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 5 | PRO A 43THR A 47PRO A 48CYH A 50ARG A 126 | None | 0.49A | 1h4oG-3a5wA:16.3 | 1h4oG-3a5wA:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b1r | RIBOKINASE, PUTATIVE (Burkholderiathailandensis) |
PF00294(PfkB) | 4 | PRO A 143GLY A 142LEU A 179PHE A 174 | AMP A 501 (-4.6A)NoneNoneNone | 0.84A | 1h4oG-3b1rA:undetectable | 1h4oG-3b1rA:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bwx | ALPHA/BETA HYDROLASE (Novosphingobiumaromaticivorans) |
PF12697(Abhydrolase_6) | 4 | PRO A 228PRO A 252GLY A 253ARG A 283 | None | 0.85A | 1h4oG-3bwxA:undetectable | 1h4oG-3bwxA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cf0 | TRANSITIONALENDOPLASMICRETICULUM ATPASE (Mus musculus) |
PF00004(AAA)PF09336(Vps4_C) | 4 | PRO A 648PRO A 520GLY A 521CYH A 522 | NoneADP A 900 ( 4.9A)ADP A 900 (-3.4A)None | 0.82A | 1h4oG-3cf0A:undetectable | 1h4oG-3cf0A:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d3a | BETA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
PF01301(Glyco_hydro_35) | 4 | PRO A 55GLY A 578CYH A 579PHE A 305 | None | 0.85A | 1h4oG-3d3aA:undetectable | 1h4oG-3d3aA:15.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ddl | XANTHORHODOPSIN (Salinibacterruber) |
PF01036(Bac_rhodopsin) | 4 | PRO A 218THR A 221PRO A 222GLY A 223 | None | 0.83A | 1h4oG-3ddlA:undetectable | 1h4oG-3ddlA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3drn | PEROXIREDOXIN,BACTERIOFERRITINCOMIGRATORY PROTEINHOMOLOG (Sulfolobussolfataricus) |
PF00578(AhpC-TSA) | 5 | PRO A 38THR A 42PRO A 43GLY A 44ARG A 112 | CIT A 500 (-3.6A)CIT A 500 (-2.9A)CIT A 500 (-3.6A)CIT A 500 (-2.9A)CIT A 500 (-3.7A) | 0.39A | 1h4oG-3drnA:19.4 | 1h4oG-3drnA:25.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gi8 | UNCHARACTERIZEDPROTEIN MJ0609 (Methanocaldococcusjannaschii) |
PF13520(AA_permease_2) | 4 | THR C 408GLY C 411LEU C 333PHE C 334 | None | 0.76A | 1h4oG-3gi8C:undetectable | 1h4oG-3gi8C:16.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gyr | PHENOXAZINONESYNTHASE (Streptomycesantibioticus) |
PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 4 | THR A 450GLY A 452PHE A 546ARG A 496 | None | 0.82A | 1h4oG-3gyrA:undetectable | 1h4oG-3gyrA:16.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h2y | GTPASE FAMILYPROTEIN (Bacillusanthracis) |
PF01926(MMR_HSR1) | 4 | THR A 218PRO A 219GLY A 220LEU A 63 | None | 0.82A | 1h4oG-3h2yA:undetectable | 1h4oG-3h2yA:18.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h4i | GLYCOSYLTRANSFERASEGTFA,GLYCOSYLTRANSFERASE (Actinoplanesteichomyceticus;Amycolatopsisorientalis) |
PF03033(Glyco_transf_28)PF04101(Glyco_tran_28_C) | 4 | THR A 351PRO A 352GLY A 353ARG A 357 | None | 0.75A | 1h4oG-3h4iA:2.7 | 1h4oG-3h4iA:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ixr | BACTERIOFERRITINCOMIGRATORY PROTEIN (Xylellafastidiosa) |
PF00578(AhpC-TSA) | 5 | PRO A 40THR A 44PRO A 45GLY A 46ARG A 122 | None | 0.43A | 1h4oG-3ixrA:18.9 | 1h4oG-3ixrA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jxa | CONTACTIN 4 (Mus musculus) |
PF07679(I-set)PF13927(Ig_3) | 5 | PRO A 208PRO A 146GLY A 145LEU A 206ARG A 129 | None | 1.48A | 1h4oG-3jxaA:undetectable | 1h4oG-3jxaA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kw7 | LACCASE B (Trametes sp.AH28-2) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 4 | PRO A 4GLY A 3LEU A 68PHE A 97 | None | 0.86A | 1h4oG-3kw7A:undetectable | 1h4oG-3kw7A:17.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mn3 | CARBONCATABOLITE-DEREPRESSING PROTEIN KINASE (Saccharomycescerevisiae) |
PF00069(Pkinase) | 4 | GLY A 213CYH A 212LEU A 260PHE A 261 | None | 0.77A | 1h4oG-3mn3A:undetectable | 1h4oG-3mn3A:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nrn | UNCHARACTERIZEDPROTEIN PF1083 (Pyrococcusfuriosus) |
PF01593(Amino_oxidase) | 4 | PRO A 181PRO A 83GLY A 85LEU A 183 | None | 0.84A | 1h4oG-3nrnA:undetectable | 1h4oG-3nrnA:18.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oep | PUTATIVEUNCHARACTERIZEDPROTEIN TTHA0988 (Thermusthermophilus) |
PF02626(CT_A_B)PF02682(CT_C_D) | 5 | PRO A 186PRO A 121GLY A 122LEU A 346PHE A 345 | None | 1.30A | 1h4oG-3oepA:undetectable | 1h4oG-3oepA:17.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p7x | PROBABLE THIOLPEROXIDASE (Staphylococcusaureus) |
PF08534(Redoxin) | 5 | PRO A 53THR A 57CYH A 60LEU A 123ARG A 128 | None | 0.92A | 1h4oG-3p7xA:18.7 | 1h4oG-3p7xA:26.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qpm | PEROXIREDOXIN (Larimichthyscrocea) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 4 | PRO A 106THR A 110CYH A 113ARG A 189 | None | 0.57A | 1h4oG-3qpmA:16.6 | 1h4oG-3qpmA:24.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3su8 | PLEXIN-B1 (Homo sapiens) |
PF08337(Plexin_cytopl) | 4 | PRO X1584PRO X1578GLY X1579LEU X1640 | None | 0.83A | 1h4oG-3su8X:undetectable | 1h4oG-3su8X:13.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tb2 | 1-CYS PEROXIREDOXIN (Plasmodiumyoelii) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 5 | PRO A 40THR A 44PRO A 45CYH A 47ARG A 129 | GOL A 223 (-4.3A)GOL A 223 ( 4.3A)GOL A 223 (-3.6A)GOL A 223 (-4.4A)GOL A 223 (-4.1A) | 0.56A | 1h4oG-3tb2A:17.6 | 1h4oG-3tb2A:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tkr | PEROXIREDOXIN-4 (Homo sapiens) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 4 | PRO A 80THR A 84CYH A 87ARG A 163 | None | 0.57A | 1h4oG-3tkrA:18.6 | 1h4oG-3tkrA:26.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uk1 | TRANSKETOLASE (Burkholderiathailandensis) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 4 | THR A 126PRO A 127GLY A 128LEU A 107 | None | 0.49A | 1h4oG-3uk1A:undetectable | 1h4oG-3uk1A:15.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3uma | HYPOTHETICALPEROXIREDOXINPROTEIN (Sinorhizobiummeliloti) |
PF08534(Redoxin) | 5 | PRO A 42THR A 46PRO A 47CYH A 49ARG A 127 | None | 0.16A | 1h4oG-3umaA:27.6 | 1h4oG-3umaA:37.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3up4 | OTEMO (Pseudomonasputida) |
PF00743(FMO-like) | 4 | THR A 222PRO A 223LEU A 305PHE A 333 | None | 0.84A | 1h4oG-3up4A:undetectable | 1h4oG-3up4A:16.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vxi | DYP (Bjerkanderaadusta) |
PF04261(Dyp_perox) | 4 | PRO A 187GLY A 188LEU A 281ARG A 315 | NoneASC A 502 (-4.6A)NoneHEM A 501 ( 3.9A) | 0.84A | 1h4oG-3vxiA:undetectable | 1h4oG-3vxiA:18.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zl8 | UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE (Thermotogamaritima) |
PF01225(Mur_ligase)PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 4 | THR A 113PRO A 114GLY A 115LEU A 152 | None | 0.78A | 1h4oG-3zl8A:undetectable | 1h4oG-3zl8A:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zre | THIOL PEROXIDASE (Yersiniapseudotuberculosis) |
PF08534(Redoxin) | 4 | PRO A 54THR A 58CYH A 61ARG A 133 | None | 0.44A | 1h4oG-3zreA:18.1 | 1h4oG-3zreA:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4af2 | THIOL PEROXIDASE (Escherichiacoli) |
PF08534(Redoxin) | 4 | PRO A 54THR A 58LEU A 127ARG A 133 | None | 0.83A | 1h4oG-4af2A:18.7 | 1h4oG-4af2A:24.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c1q | HISTONE-LYSINEN-METHYLTRANSFERASEPRDM9 (Mus musculus) |
PF00856(SET) | 4 | PRO A 244GLY A 245LEU A 271PHE A 273 | None | 0.80A | 1h4oG-4c1qA:undetectable | 1h4oG-4c1qA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c7g | BETA-N-ACETYLHEXOSAMINIDASE (Streptomycescoelicolor) |
PF00728(Glyco_hydro_20)PF02838(Glyco_hydro_20b) | 4 | THR A 291PRO A 292GLY A 293LEU A 175 | None | 0.73A | 1h4oG-4c7gA:undetectable | 1h4oG-4c7gA:16.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c7v | TRANSKETOLASE (Lactobacillussalivarius) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | PRO A 101THR A 109GLY A 107CYH A 108LEU A 74 | None | 1.39A | 1h4oG-4c7vA:undetectable | 1h4oG-4c7vA:14.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4chl | PERSULFIDEDIOXYGENASE ETHE1,MITOCHONDRIAL (Homo sapiens) |
PF00753(Lactamase_B) | 4 | THR A 136PRO A 137GLY A 138CYH A 139 | None | 0.78A | 1h4oG-4chlA:undetectable | 1h4oG-4chlA:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d82 | AAA ATPASE, CENTRALDOMAIN PROTEIN (Metallosphaerasedula) |
PF00004(AAA)PF09336(Vps4_C) | 4 | PRO A 270PRO A 140GLY A 141CYH A 142 | NoneNoneADP A1367 (-3.2A)None | 0.80A | 1h4oG-4d82A:undetectable | 1h4oG-4d82A:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eo3 | BACTERIOFERRITINCOMIGRATORYPROTEIN/NADHDEHYDROGENASE (Thermotogamaritima) |
PF00578(AhpC-TSA)PF00881(Nitroreductase) | 4 | PRO A 33THR A 37GLY A 39ARG A 103 | NoneSO4 A 402 (-3.4A)SO4 A 402 (-3.3A)SO4 A 402 (-3.5A) | 0.40A | 1h4oG-4eo3A:17.8 | 1h4oG-4eo3A:20.24 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4f82 | THIOREDOXINREDUCTASE (Burkholderiacenocepacia) |
PF08534(Redoxin) | 5 | PRO A 48THR A 52PRO A 53CYH A 55ARG A 133 | None | 0.18A | 1h4oG-4f82A:27.4 | 1h4oG-4f82A:42.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4f82 | THIOREDOXINREDUCTASE (Burkholderiacenocepacia) |
PF08534(Redoxin) | 5 | THR A 52PRO A 53CYH A 55LEU A 122ARG A 133 | None | 0.68A | 1h4oG-4f82A:27.4 | 1h4oG-4f82A:42.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gxw | ADENOSINE DEAMINASE (Burkholderiaambifaria) |
PF00962(A_deaminase) | 4 | PRO A 9THR A 4PRO A 5GLY A 6 | None | 0.80A | 1h4oG-4gxwA:undetectable | 1h4oG-4gxwA:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k1f | TRYPAREDOXINPEROXIDASE (Leishmaniamajor) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 4 | PRO A 45THR A 49CYH A 52ARG A 128 | NonePGE A 201 ( 4.1A)NoneNone | 0.51A | 1h4oG-4k1fA:17.3 | 1h4oG-4k1fA:24.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lgm | VPS4 AAA ATPASE (Sulfolobussolfataricus) |
PF00004(AAA)PF09336(Vps4_C) | 4 | PRO A 273PRO A 143GLY A 144CYH A 145 | NoneNone CL A 401 ( 4.4A)None | 0.72A | 1h4oG-4lgmA:undetectable | 1h4oG-4lgmA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4llr | TRYPAREDOXINPEROXIDASE (Trypanosomacruzi) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 4 | PRO A 45THR A 49CYH A 52ARG A 128 | None | 0.49A | 1h4oG-4llrA:17.3 | 1h4oG-4llrA:27.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tkt | AT-LESS POLYKETIDESYNTHASE (Streptomycesplatensis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | PRO A3312GLY A3337CYH A3339LEU A3329PHE A3268 | None | 1.46A | 1h4oG-4tktA:undetectable | 1h4oG-4tktA:14.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tmk | PROTEIN (THYMIDYLATEKINASE) (Escherichiacoli) |
PF02223(Thymidylate_kin) | 4 | PRO A 133GLY A 98LEU A 128PHE A 131 | None | 0.81A | 1h4oG-4tmkA:undetectable | 1h4oG-4tmkA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u9i | PERIPLASMIC [NIFE]HYDROGENASE LARGESUBUNIT (Desulfovibriovulgaris) |
PF00374(NiFeSe_Hases) | 4 | THR L 293GLY L 291LEU L 392PHE L 296 | NoneNoneMPD L 604 ( 4.4A)None | 0.76A | 1h4oG-4u9iL:undetectable | 1h4oG-4u9iL:17.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c04 | PUTATIVEPEROXIREDOXIN MT2298 (Mycobacteriumtuberculosis) |
PF00578(AhpC-TSA) | 4 | PRO A 38THR A 42CYH A 45ARG A 116 | None | 0.50A | 1h4oG-5c04A:19.4 | 1h4oG-5c04A:23.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c1b | TRANSITIONALENDOPLASMICRETICULUM ATPASE (Homo sapiens) |
PF00004(AAA)PF02359(CDC48_N)PF02933(CDC48_2)PF09336(Vps4_C) | 4 | PRO A 238LEU A 222PHE A 230ARG A 365 | None | 0.84A | 1h4oG-5c1bA:undetectable | 1h4oG-5c1bA:12.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5co8 | NUCLEASE-LIKEPROTEIN (Chaetomiumthermophilum) |
PF00752(XPG_N)PF00867(XPG_I) | 4 | PRO A 206GLY A 207CYH A 208LEU A 244 | None | 0.70A | 1h4oG-5co8A:undetectable | 1h4oG-5co8A:17.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5coa | IRIDOID SYNTHASE (Catharanthusroseus) |
no annotation | 4 | THR A 54PRO A 55GLY A 56LEU A 45 | None | 0.55A | 1h4oG-5coaA:2.2 | 1h4oG-5coaA:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5elx | ATP-DEPENDENT RNAHELICASE DBP5 (Saccharomycescerevisiae) |
PF00270(DEAD)PF00271(Helicase_C) | 4 | PRO A 198THR A 215PRO A 216GLY A 217 | U B 5 ( 4.3A) U B 5 ( 3.5A) U B 4 ( 3.8A) U B 5 ( 3.3A) | 0.57A | 1h4oG-5elxA:undetectable | 1h4oG-5elxA:17.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5enu | ALKYL HYDROPEROXIDEREDUCTASE/ THIOLSPECIFICANTIOXIDANT/ MALALLERGEN (Burkholderiaambifaria) |
PF00578(AhpC-TSA) | 6 | PRO A 37THR A 41PRO A 42GLY A 43CYH A 44ARG A 119 | None | 0.34A | 1h4oG-5enuA:18.9 | 1h4oG-5enuA:25.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5epf | PEROXIREDOXIN (Mycobacteriumtuberculosis) |
PF00578(AhpC-TSA) | 6 | PRO A 45THR A 49PRO A 50GLY A 51CYH A 52ARG A 124 | None | 0.90A | 1h4oG-5epfA:20.8 | 1h4oG-5epfA:28.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eqt | PROTEASOME-ACTIVATING NUCLEOTIDASE (Pyrococcushorikoshii) |
PF00004(AAA) | 4 | PRO A 277PRO A 149GLY A 150CYH A 151 | NoneACT A 402 ( 3.6A)ADP A 401 (-3.1A)None | 0.80A | 1h4oG-5eqtA:undetectable | 1h4oG-5eqtA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ipg | BACTERIOFERRITINCOMIGRATORY PROTEIN (Xanthomonascampestris) |
PF00578(AhpC-TSA) | 6 | PRO A 41THR A 45PRO A 46GLY A 47CYH A 48ARG A 123 | None | 0.68A | 1h4oG-5ipgA:18.0 | 1h4oG-5ipgA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jcg | THIOREDOXIN-DEPENDENT PEROXIDEREDUCTASE,MITOCHONDRIAL (Homo sapiens) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 4 | PRO A 40THR A 44CYH A 47ARG A 123 | None | 0.53A | 1h4oG-5jcgA:17.5 | 1h4oG-5jcgA:27.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jg7 | FUR REGULATEDSALMONELLA IRONTRANSPORTER (Salmonellaenterica) |
PF01297(ZnuA) | 4 | THR A 69PRO A 70GLY A 71ARG A 75 | None | 0.86A | 1h4oG-5jg7A:undetectable | 1h4oG-5jg7A:21.98 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5k1g | 1-CYS PEROXIREDOXIN (Vibriovulnificus) |
PF08534(Redoxin) | 5 | PRO A 41THR A 45PRO A 46PHE A 117ARG A 124 | None | 0.94A | 1h4oG-5k1gA:27.9 | 1h4oG-5k1gA:43.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kwa | PROTEASOME-ASSOCIATED ATPASE (Mycobacteriumtuberculosis) |
PF00004(AAA)PF16450(Prot_ATP_ID_OB) | 4 | PRO A 440PRO A 295GLY A 296CYH A 297 | NoneADP A 701 (-4.9A)ADP A 701 (-3.3A)None | 0.83A | 1h4oG-5kwaA:undetectable | 1h4oG-5kwaA:17.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o5d | GLUCANASE (Trichodermaatroviride) |
no annotation | 4 | PRO A 382THR A 389PRO A 390GLY A 391 | NoneNoneGOL A 609 ( 4.8A)GOL A 609 (-4.0A) | 0.83A | 1h4oG-5o5dA:undetectable | 1h4oG-5o5dA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x3d | PHOSPHOENOLPYRUVATEPHOSPHOMUTASE (Streptomyceswedmorensis) |
PF01467(CTP_transf_like) | 4 | PRO A 17THR A 124PRO A 125GLY A 126 | None7XL A 201 (-4.4A)NoneNone | 0.66A | 1h4oG-5x3dA:undetectable | 1h4oG-5x3dA:24.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xbq | PEROXIREDOXIN (Pyrococcushorikoshii) |
no annotation | 4 | PRO A 39THR A 43PRO A 44ARG A 121 | OCS A 46 ( 3.3A)OCS A 46 ( 3.6A)NoneOCS A 46 ( 2.3A) | 0.42A | 1h4oG-5xbqA:18.1 | 1h4oG-5xbqA:undetectable |