SIMILAR PATTERNS OF AMINO ACIDS FOR 1H4O_C_BEZC1162

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c7o CYSTALYSIN

(Treponema
denticola) 		PF00155
(Aminotran_1_2) 		5 THR A  68
PRO A  67
GLY A  66
THR A 275
GLY A 277
 None
 1.32A 1h4oC-1c7oA:
undetectable
1h4oD-1c7oA:
undetectable		 1h4oC-1c7oA:
17.88
1h4oD-1c7oA:
17.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1h4o PEROXIREDOXIN 5

(Homo sapiens) 		PF08534
(Redoxin) 		8 PRO A  40
THR A  44
PRO A  45
GLY A  46
CYH A  47
PHE A 120
ARG A 127
THR A 147
 BEZ  A1162 (-4.5A)
BEZ  A1162 (-4.0A)
BEZ  A1162 (-3.7A)
BEZ  A1162 (-3.1A)
BEZ  A1162 (-3.3A)
None
BEZ  A1162 (-3.7A)
BEZ  A1162 ( 4.0A)
 0.26A 1h4oC-1h4oA:
35.6
1h4oD-1h4oA:
35.6		 1h4oC-1h4oA:
100.00
1h4oD-1h4oA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j33 COBT

(Thermus
thermophilus) 		PF02277
(DBI_PRT) 		5 PRO A 253
PRO A 281
GLY A 282
THR A 168
GLY A 190
 None
 1.34A 1h4oC-1j33A:
undetectable
1h4oD-1j33A:
undetectable		 1h4oC-1j33A:
19.17
1h4oD-1j33A:
19.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1nm3 PROTEIN HI0572

(Haemophilus
influenzae) 		PF00462
(Glutaredoxin)
PF08534
(Redoxin) 		6 PRO A  42
THR A  46
PRO A  47
CYH A  49
PHE A 120
ARG A 126
 None
 0.60A 1h4oC-1nm3A:
24.1
1h4oD-1nm3A:
24.0		 1h4oC-1nm3A:
32.12
1h4oD-1nm3A:
32.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rh1 COLICIN B

(Escherichia
coli) 		PF01024
(Colicin)
PF03515
(Cloacin) 		5 PRO A 120
GLY A 258
ARG A 119
THR A  18
GLY A  16
 None
 1.40A 1h4oC-1rh1A:
undetectable
1h4oD-1rh1A:
undetectable		 1h4oC-1rh1A:
15.76
1h4oD-1rh1A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rqg METHIONYL-TRNA
SYNTHETASE

(Pyrococcus
abyssi) 		PF08264
(Anticodon_1)
PF09334
(tRNA-synt_1g) 		5 PRO A  11
PRO A  16
GLY A  15
PHE A  82
THR A  49
 None
 1.40A 1h4oC-1rqgA:
2.6
1h4oD-1rqgA:
3.0		 1h4oC-1rqgA:
14.37
1h4oD-1rqgA:
14.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tp9 PEROXIREDOXIN

(Populus
trichocarpa) 		PF08534
(Redoxin) 		5 PRO A  44
THR A  48
PRO A  49
CYH A  51
ARG A 129
 None
SO4  A1248 ( 4.6A)
SO4  A1248 (-3.6A)
None
None
 0.17A 1h4oC-1tp9A:
26.5
1h4oD-1tp9A:
26.6		 1h4oC-1tp9A:
43.45
1h4oD-1tp9A:
43.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a4v PEROXIREDOXIN DOT5

(Saccharomyces
cerevisiae) 		PF00578
(AhpC-TSA) 		5 PRO A 100
THR A 104
PRO A 105
GLY A 106
ARG A 175
 None
 0.64A 1h4oC-2a4vA:
20.1
1h4oD-2a4vA:
20.1		 1h4oC-2a4vA:
26.47
1h4oD-2a4vA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2abq FRUCTOSE 1-PHOSPHATE
KINASE

(Bacillus
halodurans) 		PF00294
(PfkB) 		5 PRO A  35
GLY A  36
PHE A  80
THR A  87
GLY A  64
 None
 1.41A 1h4oC-2abqA:
undetectable
1h4oD-2abqA:
2.2		 1h4oC-2abqA:
22.22
1h4oD-2abqA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eae ALPHA-FUCOSIDASE

(Bifidobacterium
bifidum) 		PF14498
(Glyco_hyd_65N_2) 		5 PRO A  52
THR A  61
GLY A  59
PHE A 757
GLY A 398
 None
 1.44A 1h4oC-2eaeA:
undetectable
1h4oD-2eaeA:
undetectable		 1h4oC-2eaeA:
11.35
1h4oD-2eaeA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f6d GLUCOAMYLASE GLU1

(Saccharomycopsis
fibuligera) 		PF00723
(Glyco_hydro_15) 		5 PRO A 126
THR A  68
GLY A 146
PHE A 128
GLY A 122
 None
 1.35A 1h4oC-2f6dA:
undetectable
1h4oD-2f6dA:
undetectable		 1h4oC-2f6dA:
16.02
1h4oD-2f6dA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gou OXIDOREDUCTASE,
FMN-BINDING

(Shewanella
oneidensis) 		PF00724
(Oxidored_FMN) 		5 THR A  59
PRO A  72
GLY A  73
PHE A 175
GLY A  82
 None
 1.17A 1h4oC-2gouA:
undetectable
1h4oD-2gouA:
undetectable		 1h4oC-2gouA:
19.40
1h4oD-2gouA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qs8 XAA-PRO DIPEPTIDASE

(Alteromonas
macleodii) 		PF01979
(Amidohydro_1) 		5 PRO A 135
THR A 102
GLY A 106
PHE A  72
THR A 109
 None
 1.33A 1h4oC-2qs8A:
undetectable
1h4oD-2qs8A:
undetectable		 1h4oC-2qs8A:
22.78
1h4oD-2qs8A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vn7 GLUCOAMYLASE

(Trichoderma
reesei) 		PF00686
(CBM_20)
PF00723
(Glyco_hydro_15) 		5 PRO A 107
THR A  52
GLY A 127
PHE A 109
GLY A 103
 None
 1.30A 1h4oC-2vn7A:
undetectable
1h4oD-2vn7A:
undetectable		 1h4oC-2vn7A:
12.79
1h4oD-2vn7A:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vx2 ENOYL-COA HYDRATASE
DOMAIN-CONTAINING
PROTEIN 3

(Homo sapiens) 		PF00378
(ECH_1) 		5 THR A 174
PRO A 175
GLY A 176
CYH A 183
GLY A 106
 None
 1.27A 1h4oC-2vx2A:
undetectable
1h4oD-2vx2A:
undetectable		 1h4oC-2vx2A:
22.66
1h4oD-2vx2A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus) 		PF08534
(Redoxin) 		5 PRO A  54
THR A  58
PRO A  59
CYH A  61
ARG A 132
 None
 0.45A 1h4oC-2yzhA:
19.0
1h4oD-2yzhA:
19.1		 1h4oC-2yzhA:
24.19
1h4oD-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yzh PROBABLE THIOL
PEROXIDASE

(Aquifex
aeolicus) 		PF08534
(Redoxin) 		5 THR A  58
PRO A  59
CYH A  61
ARG A 132
THR A 153
 None
 0.76A 1h4oC-2yzhA:
19.0
1h4oD-2yzhA:
19.1		 1h4oC-2yzhA:
24.19
1h4oD-2yzhA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a5w PROBABLE
PEROXIREDOXIN

(Aeropyrum
pernix) 		PF00578
(AhpC-TSA)
PF10417
(1-cysPrx_C) 		5 PRO A  43
THR A  47
PRO A  48
CYH A  50
ARG A 126
 None
 0.53A 1h4oC-3a5wA:
16.3
1h4oD-3a5wA:
16.3		 1h4oC-3a5wA:
23.65
1h4oD-3a5wA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bt3 GLYOXALASE-RELATED
ENZYME, ARAC TYPE

(Lachnoclostridium
phytofermentans) 		no annotation 5 THR A 252
GLY A 255
CYH A 256
PHE A 158
THR A 148
 None
 1.14A 1h4oC-3bt3A:
undetectable
1h4oD-3bt3A:
undetectable		 1h4oC-3bt3A:
21.51
1h4oD-3bt3A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bzm MENAQUINONE-SPECIFIC
ISOCHORISMATE
SYNTHASE

(Escherichia
coli) 		PF00425
(Chorismate_bind) 		5 PRO A  20
THR A  22
PRO A  23
GLY A  24
ARG A  26
 None
 1.29A 1h4oC-3bzmA:
undetectable
1h4oD-3bzmA:
undetectable		 1h4oC-3bzmA:
16.55
1h4oD-3bzmA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE

(Aspergillus
fumigatus) 		PF01266
(DAO) 		5 THR A 234
PRO A 233
ARG A 403
THR A 340
GLY A 361
 None
 1.19A 1h4oC-3djdA:
undetectable
1h4oD-3djdA:
undetectable		 1h4oC-3djdA:
17.62
1h4oD-3djdA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3drn PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG

(Sulfolobus
solfataricus) 		PF00578
(AhpC-TSA) 		5 PRO A  38
THR A  42
PRO A  43
GLY A  44
ARG A 112
 CIT  A 500 (-3.6A)
CIT  A 500 (-2.9A)
CIT  A 500 (-3.6A)
CIT  A 500 (-2.9A)
CIT  A 500 (-3.7A)
 0.42A 1h4oC-3drnA:
19.4
1h4oD-3drnA:
19.4		 1h4oC-3drnA:
25.15
1h4oD-3drnA:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hmu AMINOTRANSFERASE,
CLASS III

(Ruegeria
pomeroyi) 		PF00202
(Aminotran_3) 		5 PRO A 229
THR A 270
GLY A 266
CYH A 265
THR A 276
 None
 1.39A 1h4oC-3hmuA:
undetectable
1h4oD-3hmuA:
undetectable		 1h4oC-3hmuA:
15.50
1h4oD-3hmuA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ixr BACTERIOFERRITIN
COMIGRATORY PROTEIN

(Xylella
fastidiosa) 		PF00578
(AhpC-TSA) 		5 PRO A  40
THR A  44
PRO A  45
GLY A  46
ARG A 122
 None
 0.50A 1h4oC-3ixrA:
18.9
1h4oD-3ixrA:
18.9		 1h4oC-3ixrA:
20.83
1h4oD-3ixrA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY

(Desulfitobacterium
hafniense) 		PF04016
(DUF364)
PF13938
(DUF4213) 		5 PRO A 201
THR A 203
PRO A 204
CYH A 175
GLY A  37
 EDO  A 307 ( 4.1A)
None
None
None
None
 1.48A 1h4oC-3l5oA:
undetectable
1h4oD-3l5oA:
undetectable		 1h4oC-3l5oA:
20.65
1h4oD-3l5oA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tb2 1-CYS PEROXIREDOXIN

(Plasmodium
yoelii) 		PF00578
(AhpC-TSA)
PF10417
(1-cysPrx_C) 		5 PRO A  40
THR A  44
PRO A  45
CYH A  47
ARG A 129
 GOL  A 223 (-4.3A)
GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-4.4A)
GOL  A 223 (-4.1A)
 0.57A 1h4oC-3tb2A:
17.5
1h4oD-3tb2A:
17.5		 1h4oC-3tb2A:
20.69
1h4oD-3tb2A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tr5 PEPTIDE CHAIN
RELEASE FACTOR 3

(Coxiella
burnetii) 		PF00009
(GTP_EFTU)
PF16658
(RF3_C) 		5 PRO A 274
THR A   7
PRO A 357
GLY A 358
GLY A 277
 None
 1.26A 1h4oC-3tr5A:
undetectable
1h4oD-3tr5A:
undetectable		 1h4oC-3tr5A:
16.25
1h4oD-3tr5A:
16.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN

(Sinorhizobium
meliloti) 		PF08534
(Redoxin) 		5 PRO A  42
THR A  46
PRO A  47
CYH A  49
ARG A 127
 None
 0.17A 1h4oC-3umaA:
27.4
1h4oD-3umaA:
27.5		 1h4oC-3umaA:
37.10
1h4oD-3umaA:
37.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ab4 XENOBIOTIC REDUCTASE
B

(Pseudomonas
putida) 		PF00724
(Oxidored_FMN) 		5 THR A  57
PRO A  70
GLY A  71
PHE A 167
GLY A  80
 None
 1.25A 1h4oC-4ab4A:
undetectable
1h4oD-4ab4A:
undetectable		 1h4oC-4ab4A:
19.20
1h4oD-4ab4A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b3i FATTY ACID
BETA-OXIDATION
COMPLEX ALPHA-CHAIN
FADB

(Mycobacterium
tuberculosis) 		PF00378
(ECH_1)
PF00725
(3HCDH)
PF02737
(3HCDH_N) 		5 PRO A 444
THR A 440
PHE A 509
THR A 446
GLY A 478
 None
 1.33A 1h4oC-4b3iA:
undetectable
1h4oD-4b3iA:
undetectable		 1h4oC-4b3iA:
13.99
1h4oD-4b3iA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c3y 3-KETOSTEROID
DEHYDROGENASE

(Rhodococcus
erythropolis) 		PF00890
(FAD_binding_2) 		5 THR A  45
PRO A 254
GLY A 253
THR A 449
GLY A 231
 FAD  A 551 (-3.9A)
None
None
None
None
 1.26A 1h4oC-4c3yA:
undetectable
1h4oD-4c3yA:
2.2		 1h4oC-4c3yA:
16.34
1h4oD-4c3yA:
16.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4f82 THIOREDOXIN
REDUCTASE

(Burkholderia
cenocepacia) 		PF08534
(Redoxin) 		5 PRO A  48
THR A  52
PRO A  53
CYH A  55
ARG A 133
 None
 0.15A 1h4oC-4f82A:
27.4
1h4oD-4f82A:
27.4		 1h4oC-4f82A:
42.05
1h4oD-4f82A:
42.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jip GTN REDUCTASE

(Agrobacterium
tumefaciens) 		PF00724
(Oxidored_FMN) 		5 THR A  56
PRO A  69
GLY A  70
PHE A 172
GLY A  79
 None
 1.27A 1h4oC-4jipA:
undetectable
1h4oD-4jipA:
undetectable		 1h4oC-4jipA:
19.79
1h4oD-4jipA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oj5 TAILSPIKE PROTEIN

(Escherichia
virus CBA120) 		no annotation 5 PRO A 480
PRO A 538
GLY A 506
PHE A 493
THR A 503
 None
 1.40A 1h4oC-4oj5A:
undetectable
1h4oD-4oj5A:
undetectable		 1h4oC-4oj5A:
12.02
1h4oD-4oj5A:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4piv FATTY ACID SYNTHASE

(Homo sapiens) 		PF08242
(Methyltransf_12)
PF08659
(KR) 		5 THR A1120
PRO A1121
GLY A1512
PHE A1517
THR A1230
 None
 1.34A 1h4oC-4pivA:
undetectable
1h4oD-4pivA:
undetectable		 1h4oC-4pivA:
13.43
1h4oD-4pivA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE

(Aspergillus
fumigatus) 		PF01266
(DAO) 		5 THR A 239
PRO A 238
ARG A 410
THR A 347
GLY A 368
 None
 1.18A 1h4oC-4wctA:
undetectable
1h4oD-4wctA:
undetectable		 1h4oC-4wctA:
15.73
1h4oD-4wctA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y0x SERINE/THREONINE-PRO
TEIN KINASE PKNG

(Mycobacterium
tuberculosis) 		PF00069
(Pkinase)
PF16919
(PknG_rubred) 		5 THR A 309
PRO A 310
GLY A 311
THR A 344
GLY A 347
 None
 1.25A 1h4oC-4y0xA:
undetectable
1h4oD-4y0xA:
undetectable		 1h4oC-4y0xA:
17.60
1h4oD-4y0xA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dxx ARTEMISINIC ALDEHYDE
DELTA(11(13))
REDUCTASE

(Artemisia annua) 		PF00724
(Oxidored_FMN) 		5 THR A  60
PRO A  73
GLY A  74
PHE A 174
GLY A  83
 None
 1.27A 1h4oC-5dxxA:
undetectable
1h4oD-5dxxA:
undetectable		 1h4oC-5dxxA:
18.85
1h4oD-5dxxA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN

(Burkholderia
ambifaria) 		PF00578
(AhpC-TSA) 		6 PRO A  37
THR A  41
PRO A  42
GLY A  43
CYH A  44
ARG A 119
 None
 0.37A 1h4oC-5enuA:
18.9
1h4oD-5enuA:
18.9		 1h4oC-5enuA:
25.41
1h4oD-5enuA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5epf PEROXIREDOXIN

(Mycobacterium
tuberculosis) 		PF00578
(AhpC-TSA) 		6 PRO A  45
THR A  49
PRO A  50
GLY A  51
CYH A  52
ARG A 124
 None
 0.92A 1h4oC-5epfA:
21.0
1h4oD-5epfA:
21.0		 1h4oC-5epfA:
28.65
1h4oD-5epfA:
28.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fie CELL SURFACE PROTEIN
SPAA

(Lactobacillus
rhamnosus) 		no annotation 5 PRO A 170
GLY A  49
PHE A  78
THR A  46
GLY A 113
 None
 1.32A 1h4oC-5fieA:
undetectable
1h4oD-5fieA:
undetectable		 1h4oC-5fieA:
22.22
1h4oD-5fieA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ipg BACTERIOFERRITIN
COMIGRATORY PROTEIN

(Xanthomonas
campestris) 		PF00578
(AhpC-TSA) 		6 PRO A  41
THR A  45
PRO A  46
GLY A  47
CYH A  48
ARG A 123
 None
 0.69A 1h4oC-5ipgA:
18.1
1h4oD-5ipgA:
18.0		 1h4oC-5ipgA:
20.24
1h4oD-5ipgA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jta NEUTRAL TREHALASE

(Saccharomyces
cerevisiae) 		no annotation 5 PRO A 271
THR A 217
PRO A 218
GLY A 219
ARG A 224
 None
 1.50A 1h4oC-5jtaA:
undetectable
1h4oD-5jtaA:
undetectable		 1h4oC-5jtaA:
13.65
1h4oD-5jtaA:
13.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5k1g 1-CYS PEROXIREDOXIN

(Vibrio
vulnificus) 		PF08534
(Redoxin) 		5 PRO A  41
THR A  45
PRO A  46
PHE A 117
ARG A 124
 None
 0.84A 1h4oC-5k1gA:
28.0
1h4oD-5k1gA:
27.9		 1h4oC-5k1gA:
43.03
1h4oD-5k1gA:
43.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k1u NAD(P)H:FLAVIN
OXIDOREDUCTASE SYE4

(Shewanella
oneidensis) 		PF00724
(Oxidored_FMN) 		5 THR A  67
PRO A  80
GLY A  81
PHE A 176
GLY A  90
 None
 1.25A 1h4oC-5k1uA:
undetectable
1h4oD-5k1uA:
undetectable		 1h4oC-5k1uA:
18.11
1h4oD-5k1uA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fhv GLUCOAMYLASE

(Penicillium
oxalicum) 		no annotation 5 PRO A 141
THR A  80
GLY A 161
PHE A 143
GLY A 137
 None
 1.30A 1h4oC-6fhvA:
undetectable
1h4oD-6fhvA:
undetectable		 1h4oC-6fhvA:
undetectable
1h4oD-6fhvA:
undetectable