SIMILAR PATTERNS OF AMINO ACIDS FOR 1H4O_B_BEZB1162_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bkh | MUCONATE LACTONIZINGENZYME (Pseudomonasputida) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | THR A 355PRO A 356GLY A 357THR A 361 | None | 0.67A | 1h4oB-1bkhA:undetectable | 1h4oB-1bkhA:19.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1buc | BUTYRYL-COADEHYDROGENASE (Megasphaeraelsdenii) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | THR A 194PRO A 195GLY A 196THR A 153 | None | 0.83A | 1h4oB-1bucA:undetectable | 1h4oB-1bucA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f8v | MATURE CAPSIDPROTEIN BETA (Pariacoto virus) |
PF01829(Peptidase_A6) | 4 | PRO A 112GLY A 113PHE A 261THR A 285 | None | 0.79A | 1h4oB-1f8vA:undetectable | 1h4oB-1f8vA:23.21 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1h4o | PEROXIREDOXIN 5 (Homo sapiens) |
PF08534(Redoxin) | 8 | PRO A 40THR A 44PRO A 45GLY A 46CYH A 47PHE A 120ARG A 127THR A 147 | BEZ A1162 (-4.5A)BEZ A1162 (-4.0A)BEZ A1162 (-3.7A)BEZ A1162 (-3.1A)BEZ A1162 (-3.3A)NoneBEZ A1162 (-3.7A)BEZ A1162 ( 4.0A) | 0.25A | 1h4oB-1h4oA:35.0 | 1h4oB-1h4oA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hcu | ALPHA-1,2-MANNOSIDASE (Trichodermareesei) |
PF01532(Glyco_hydro_47) | 4 | PRO A 352GLY A 351PHE A 375THR A 344 | None | 0.87A | 1h4oB-1hcuA:undetectable | 1h4oB-1hcuA:16.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hr7 | MITOCHONDRIALPROCESSING PEPTIDASEALPHA SUBUNITMITOCHONDRIALPROCESSING PEPTIDASEBETA SUBUNIT (Saccharomycescerevisiae;Saccharomycescerevisiae) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C)PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 4 | PRO B 43THR A 35PRO A 36GLY A 37 | None | 0.70A | 1h4oB-1hr7B:undetectable | 1h4oB-1hr7B:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k86 | CASPASE-7 (Homo sapiens) |
PF00656(Peptidase_C14) | 4 | CYH A 186PHE A 78ARG A 233THR A 90 | None | 0.66A | 1h4oB-1k86A:undetectable | 1h4oB-1k86A:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nbw | GLYCEROL DEHYDRATASEREACTIVASE ALPHASUBUNIT (Klebsiellapneumoniae) |
PF08841(DDR) | 4 | THR A 404PRO A 405GLY A 406CYH A 407 | None | 0.86A | 1h4oB-1nbwA:undetectable | 1h4oB-1nbwA:15.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1nm3 | PROTEIN HI0572 (Haemophilusinfluenzae) |
PF00462(Glutaredoxin)PF08534(Redoxin) | 6 | PRO A 42THR A 46PRO A 47CYH A 49PHE A 120ARG A 126 | None | 0.58A | 1h4oB-1nm3A:24.3 | 1h4oB-1nm3A:32.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pc3 | PHOSPHATE-BINDINGPROTEIN 1 (Mycobacteriumtuberculosis) |
PF12849(PBP_like_2) | 4 | THR A 218PRO A 219GLY A 220CYH A 221 | None | 0.72A | 1h4oB-1pc3A:undetectable | 1h4oB-1pc3A:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1psq | PROBABLE THIOLPEROXIDASE (Streptococcuspneumoniae) |
PF08534(Redoxin) | 4 | PRO A 51THR A 55CYH A 58ARG A 127 | None | 0.49A | 1h4oB-1psqA:19.5 | 1h4oB-1psqA:25.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qd1 | FORMIMINOTRANSFERASE-CYCLODEAMINASE (Sus scrofa) |
PF02971(FTCD)PF07837(FTCD_N) | 4 | THR A 30PRO A 31GLY A 32CYH A 33 | None | 0.30A | 1h4oB-1qd1A:undetectable | 1h4oB-1qd1A:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qmv | PEROXIREDOXIN-2 (Homo sapiens) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 4 | PRO A 44THR A 48CYH A 51ARG A 127 | None | 0.51A | 1h4oB-1qmvA:18.6 | 1h4oB-1qmvA:27.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tkl | COPROPORPHYRINOGENIII OXIDASE (Saccharomycescerevisiae) |
PF01218(Coprogen_oxidas) | 4 | THR A 283PRO A 284GLY A 285ARG A 46 | None | 0.82A | 1h4oB-1tklA:undetectable | 1h4oB-1tklA:20.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tp9 | PEROXIREDOXIN (Populustrichocarpa) |
PF08534(Redoxin) | 5 | PRO A 44THR A 48PRO A 49CYH A 51ARG A 129 | NoneSO4 A1248 ( 4.6A)SO4 A1248 (-3.6A)NoneNone | 0.17A | 1h4oB-1tp9A:26.7 | 1h4oB-1tp9A:43.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v7v | CHITOBIOSEPHOSPHORYLASE (Vibrioproteolyticus) |
PF06165(Glyco_transf_36)PF17167(Glyco_hydro_36) | 4 | GLY A 729PHE A 448ARG A 753THR A 442 | None | 0.81A | 1h4oB-1v7vA:undetectable | 1h4oB-1v7vA:12.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y25 | PROBABLE THIOLPEROXIDASE (Mycobacteriumtuberculosis) |
PF08534(Redoxin) | 4 | PRO A 53THR A 57PRO A 58ARG A 130 | NoneACT A1200 (-3.6A)ACT A1200 (-3.6A)ACT A1200 (-3.1A) | 0.54A | 1h4oB-1y25A:19.2 | 1h4oB-1y25A:29.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ykw | RUBISCO-LIKE PROTEIN (Chlorobaculumtepidum) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 4 | THR A 124PRO A 125GLY A 126THR A 36 | None | 0.71A | 1h4oB-1ykwA:undetectable | 1h4oB-1ykwA:19.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z60 | TFIIH BASALTRANSCRIPTION FACTORCOMPLEX P44 SUBUNIT (Homo sapiens) |
PF07975(C1_4) | 4 | PRO A 383GLY A 384CYH A 385PHE A 331 | None ZN A 2 ( 4.6A) ZN A 2 (-2.3A)None | 0.73A | 1h4oB-1z60A:undetectable | 1h4oB-1z60A:17.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zye | THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE (Bos taurus) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 4 | PRO A 40THR A 44CYH A 47ARG A 123 | None | 0.65A | 1h4oB-1zyeA:19.2 | 1h4oB-1zyeA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a4v | PEROXIREDOXIN DOT5 (Saccharomycescerevisiae) |
PF00578(AhpC-TSA) | 5 | PRO A 100THR A 104PRO A 105GLY A 106ARG A 175 | None | 0.64A | 1h4oB-2a4vA:20.3 | 1h4oB-2a4vA:26.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cx4 | BACTERIOFERRITINCOMIGRATORY PROTEIN (Aeropyrumpernix) |
PF00578(AhpC-TSA) | 4 | PRO A 42PRO A 47CYH A 49ARG A 122 | None | 0.38A | 1h4oB-2cx4A:21.1 | 1h4oB-2cx4A:28.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jjp | CYTOCHROME P450113A1 (Saccharopolysporaerythraea) |
PF00067(p450) | 4 | THR A 83PRO A 84GLY A 85THR A 236 | None | 0.67A | 1h4oB-2jjpA:undetectable | 1h4oB-2jjpA:15.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jx1 | MYELIN TRANSCRIPTIONFACTOR 1 (Mus musculus) |
PF01530(zf-C2HC) | 4 | THR A 14PRO A 15GLY A 16CYH A 17 | None | 0.78A | 1h4oB-2jx1A:undetectable | 1h4oB-2jx1A:13.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kbe | ATP-DEPENDENT RNAHELICASE DBP5 (Saccharomycescerevisiae) |
PF00270(DEAD) | 4 | PRO A 198THR A 215PRO A 216GLY A 217 | None | 0.72A | 1h4oB-2kbeA:undetectable | 1h4oB-2kbeA:23.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lex | PROBABLE WRKYTRANSCRIPTION FACTOR4 (Arabidopsisthaliana) |
PF03106(WRKY) | 4 | THR A 436PRO A 437GLY A 438CYH A 439 | ZN A 500 (-3.5A)NoneNone ZN A 500 (-2.5A) | 0.64A | 1h4oB-2lexA:undetectable | 1h4oB-2lexA:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mf8 | MYELIN TRANSCRIPTIONFACTOR 1 (Mus musculus) |
PF01530(zf-C2HC) | 4 | THR A 804PRO A 805GLY A 806CYH A 807 | ZN A 901 (-4.0A)NoneNone ZN A 901 (-1.9A) | 0.86A | 1h4oB-2mf8A:undetectable | 1h4oB-2mf8A:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mf8 | MYELIN TRANSCRIPTIONFACTOR 1 (Mus musculus) |
PF01530(zf-C2HC) | 4 | THR A 848PRO A 849GLY A 850CYH A 851 | ZN A 902 (-3.2A)NoneNone ZN A 902 (-2.3A) | 0.88A | 1h4oB-2mf8A:undetectable | 1h4oB-2mf8A:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mh1 | KALATA-B1 (Oldenlandiaaffinis) |
PF03784(Cyclotide) | 4 | THR A 15PRO A 16GLY A 17THR A 33 | None | 0.85A | 1h4oB-2mh1A:undetectable | 1h4oB-2mh1A:11.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2pwj | MITOCHONDRIALPEROXIREDOXIN (Pisum sativum) |
PF08534(Redoxin) | 4 | PRO A 52THR A 56CYH A 59ARG A 137 | None | 0.47A | 1h4oB-2pwjA:26.3 | 1h4oB-2pwjA:35.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qs8 | XAA-PRO DIPEPTIDASE (Alteromonasmacleodii) |
PF01979(Amidohydro_1) | 5 | PRO A 135THR A 102GLY A 106PHE A 72THR A 109 | None | 1.30A | 1h4oB-2qs8A:undetectable | 1h4oB-2qs8A:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rdx | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME,PUTATIVE (Roseovariusnubinhibens) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | THR A 347PRO A 348GLY A 349THR A 353 | GOL A 380 (-3.5A)GOL A 380 (-4.3A)GOL A 380 ( 3.9A)GOL A 380 (-4.1A) | 0.56A | 1h4oB-2rdxA:2.1 | 1h4oB-2rdxA:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v41 | PEROXIREDOXIN 6. (Arenicolamarina) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 4 | PRO A 38THR A 42PRO A 43ARG A 128 | BEZ A1222 ( 4.6A)BEZ A1222 (-3.6A)BEZ A1222 (-3.2A)BEZ A1222 (-3.3A) | 0.50A | 1h4oB-2v41A:18.5 | 1h4oB-2v41A:25.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vil | VILLIN 14T (Gallus gallus) |
PF00626(Gelsolin) | 4 | THR A 15PRO A 16GLY A 17THR A 33 | None | 0.61A | 1h4oB-2vilA:undetectable | 1h4oB-2vilA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vxo | GMP SYNTHASE[GLUTAMINE-HYDROLYZING] (Homo sapiens) |
PF00117(GATase)PF00958(GMP_synt_C)PF02540(NAD_synthase) | 4 | PRO A 650PRO A 687GLY A 688ARG A 638 | None | 0.75A | 1h4oB-2vxoA:undetectable | 1h4oB-2vxoA:17.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2wfc | PEROXIREDOXIN 5 (Arenicolamarina) |
PF08534(Redoxin) | 5 | PRO A 67THR A 71PRO A 72GLY A 73ARG A 152 | None | 0.60A | 1h4oB-2wfcA:31.5 | 1h4oB-2wfcA:64.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ykf | PROBABLE SENSORHISTIDINE KINASEPDTAS (Mycobacteriumtuberculosis) |
PF12282(H_kinase_N) | 4 | PRO A 115THR A 86GLY A 90ARG A 117 | None | 0.82A | 1h4oB-2ykfA:undetectable | 1h4oB-2ykfA:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yzh | PROBABLE THIOLPEROXIDASE (Aquifexaeolicus) |
PF08534(Redoxin) | 5 | PRO A 54THR A 58PRO A 59CYH A 61ARG A 132 | None | 0.46A | 1h4oB-2yzhA:19.1 | 1h4oB-2yzhA:24.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yzh | PROBABLE THIOLPEROXIDASE (Aquifexaeolicus) |
PF08534(Redoxin) | 5 | THR A 58PRO A 59CYH A 61ARG A 132THR A 153 | None | 0.77A | 1h4oB-2yzhA:19.1 | 1h4oB-2yzhA:24.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a5w | PROBABLEPEROXIREDOXIN (Aeropyrumpernix) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 5 | PRO A 43THR A 47PRO A 48CYH A 50ARG A 126 | None | 0.51A | 1h4oB-3a5wA:16.4 | 1h4oB-3a5wA:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bt3 | GLYOXALASE-RELATEDENZYME, ARAC TYPE (Lachnoclostridiumphytofermentans) |
no annotation | 5 | THR A 252GLY A 255CYH A 256PHE A 158THR A 148 | None | 1.11A | 1h4oB-3bt3A:undetectable | 1h4oB-3bt3A:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bzm | MENAQUINONE-SPECIFICISOCHORISMATESYNTHASE (Escherichiacoli) |
PF00425(Chorismate_bind) | 5 | PRO A 20THR A 22PRO A 23GLY A 24ARG A 26 | None | 1.26A | 1h4oB-3bzmA:undetectable | 1h4oB-3bzmA:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cf0 | TRANSITIONALENDOPLASMICRETICULUM ATPASE (Mus musculus) |
PF00004(AAA)PF09336(Vps4_C) | 4 | PRO A 648PRO A 520GLY A 521CYH A 522 | NoneADP A 900 ( 4.9A)ADP A 900 (-3.4A)None | 0.85A | 1h4oB-3cf0A:undetectable | 1h4oB-3cf0A:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d3a | BETA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
PF01301(Glyco_hydro_35) | 4 | PRO A 55GLY A 578CYH A 579PHE A 305 | None | 0.88A | 1h4oB-3d3aA:undetectable | 1h4oB-3d3aA:15.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3drn | PEROXIREDOXIN,BACTERIOFERRITINCOMIGRATORY PROTEINHOMOLOG (Sulfolobussolfataricus) |
PF00578(AhpC-TSA) | 5 | PRO A 38THR A 42PRO A 43GLY A 44ARG A 112 | CIT A 500 (-3.6A)CIT A 500 (-2.9A)CIT A 500 (-3.6A)CIT A 500 (-2.9A)CIT A 500 (-3.7A) | 0.42A | 1h4oB-3drnA:19.7 | 1h4oB-3drnA:25.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e9y | ACETOLACTATESYNTHASE,CHLOROPLASTIC (Arabidopsisthaliana) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | PRO A 611THR A 631PRO A 632GLY A 633 | None | 0.78A | 1h4oB-3e9yA:undetectable | 1h4oB-3e9yA:16.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ebv | CHINITASE A (Streptomycescoelicolor) |
PF00704(Glyco_hydro_18) | 4 | THR A 43PRO A 44GLY A 45THR A 98 | None | 0.53A | 1h4oB-3ebvA:undetectable | 1h4oB-3ebvA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gyr | PHENOXAZINONESYNTHASE (Streptomycesantibioticus) |
PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 4 | THR A 450GLY A 452PHE A 546ARG A 496 | None | 0.81A | 1h4oB-3gyrA:undetectable | 1h4oB-3gyrA:16.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h4i | GLYCOSYLTRANSFERASEGTFA,GLYCOSYLTRANSFERASE (Actinoplanesteichomyceticus;Amycolatopsisorientalis) |
PF03033(Glyco_transf_28)PF04101(Glyco_tran_28_C) | 4 | THR A 351PRO A 352GLY A 353ARG A 357 | None | 0.83A | 1h4oB-3h4iA:2.8 | 1h4oB-3h4iA:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hmu | AMINOTRANSFERASE,CLASS III (Ruegeriapomeroyi) |
PF00202(Aminotran_3) | 5 | PRO A 229THR A 270GLY A 266CYH A 265THR A 276 | None | 1.38A | 1h4oB-3hmuA:undetectable | 1h4oB-3hmuA:15.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ixr | BACTERIOFERRITINCOMIGRATORY PROTEIN (Xylellafastidiosa) |
PF00578(AhpC-TSA) | 5 | PRO A 40THR A 44PRO A 45GLY A 46ARG A 122 | None | 0.51A | 1h4oB-3ixrA:19.0 | 1h4oB-3ixrA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mfq | HIGH-AFFINITY ZINCUPTAKE SYSTEMPROTEIN ZNUA (Streptococcussuis) |
PF01297(ZnuA) | 4 | PRO A 67THR A 248GLY A 64THR A 40 | None | 0.82A | 1h4oB-3mfqA:undetectable | 1h4oB-3mfqA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p7x | PROBABLE THIOLPEROXIDASE (Staphylococcusaureus) |
PF08534(Redoxin) | 4 | PRO A 53THR A 57CYH A 60ARG A 128 | None | 0.52A | 1h4oB-3p7xA:18.8 | 1h4oB-3p7xA:26.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p7x | PROBABLE THIOLPEROXIDASE (Staphylococcusaureus) |
PF08534(Redoxin) | 4 | THR A 57CYH A 60ARG A 128THR A 149 | None | 0.70A | 1h4oB-3p7xA:18.8 | 1h4oB-3p7xA:26.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qpm | PEROXIREDOXIN (Larimichthyscrocea) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 4 | PRO A 106THR A 110CYH A 113ARG A 189 | None | 0.57A | 1h4oB-3qpmA:16.8 | 1h4oB-3qpmA:24.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tb2 | 1-CYS PEROXIREDOXIN (Plasmodiumyoelii) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 5 | PRO A 40THR A 44PRO A 45CYH A 47ARG A 129 | GOL A 223 (-4.3A)GOL A 223 ( 4.3A)GOL A 223 (-3.6A)GOL A 223 (-4.4A)GOL A 223 (-4.1A) | 0.54A | 1h4oB-3tb2A:17.7 | 1h4oB-3tb2A:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tkr | PEROXIREDOXIN-4 (Homo sapiens) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 4 | PRO A 80THR A 84CYH A 87ARG A 163 | None | 0.57A | 1h4oB-3tkrA:18.8 | 1h4oB-3tkrA:26.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ukf | UDP-GALACTOPYRANOSEMUTASE (Aspergillusfumigatus) |
PF13450(NAD_binding_8) | 4 | THR A 42PRO A 43GLY A 44THR A 49 | None | 0.87A | 1h4oB-3ukfA:undetectable | 1h4oB-3ukfA:15.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3uma | HYPOTHETICALPEROXIREDOXINPROTEIN (Sinorhizobiummeliloti) |
PF08534(Redoxin) | 5 | PRO A 42THR A 46PRO A 47CYH A 49ARG A 127 | None | 0.19A | 1h4oB-3umaA:27.6 | 1h4oB-3umaA:37.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zre | THIOL PEROXIDASE (Yersiniapseudotuberculosis) |
PF08534(Redoxin) | 4 | PRO A 54THR A 58CYH A 61ARG A 133 | None | 0.53A | 1h4oB-3zreA:18.3 | 1h4oB-3zreA:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zre | THIOL PEROXIDASE (Yersiniapseudotuberculosis) |
PF08534(Redoxin) | 4 | THR A 58CYH A 61ARG A 133THR A 154 | None | 0.87A | 1h4oB-3zreA:18.3 | 1h4oB-3zreA:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4chl | PERSULFIDEDIOXYGENASE ETHE1,MITOCHONDRIAL (Homo sapiens) |
PF00753(Lactamase_B) | 4 | THR A 136PRO A 137GLY A 138CYH A 139 | None | 0.85A | 1h4oB-4chlA:undetectable | 1h4oB-4chlA:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d7l | PEPTIDE METHIONINESULFOXIDE REDUCTASEMSRA (Corynebacteriumdiphtheriae) |
PF01625(PMSR) | 4 | THR A 63PRO A 64GLY A 65THR A 107 | None | 0.48A | 1h4oB-4d7lA:undetectable | 1h4oB-4d7lA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d82 | AAA ATPASE, CENTRALDOMAIN PROTEIN (Metallosphaerasedula) |
PF00004(AAA)PF09336(Vps4_C) | 4 | PRO A 270PRO A 140GLY A 141CYH A 142 | NoneNoneADP A1367 (-3.2A)None | 0.84A | 1h4oB-4d82A:undetectable | 1h4oB-4d82A:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eo3 | BACTERIOFERRITINCOMIGRATORYPROTEIN/NADHDEHYDROGENASE (Thermotogamaritima) |
PF00578(AhpC-TSA)PF00881(Nitroreductase) | 4 | PRO A 33THR A 37GLY A 39ARG A 103 | NoneSO4 A 402 (-3.4A)SO4 A 402 (-3.3A)SO4 A 402 (-3.5A) | 0.48A | 1h4oB-4eo3A:18.0 | 1h4oB-4eo3A:20.24 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4f82 | THIOREDOXINREDUCTASE (Burkholderiacenocepacia) |
PF08534(Redoxin) | 5 | PRO A 48THR A 52PRO A 53CYH A 55ARG A 133 | None | 0.16A | 1h4oB-4f82A:27.7 | 1h4oB-4f82A:42.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4frz | KINESIN-LIKECALMODULIN-BINDINGPROTEIN (Arabidopsisthaliana) |
PF00225(Kinesin) | 4 | THR A 990PRO A 991GLY A 988THR A 977 | NoneNoneNone MG A1301 ( 3.1A) | 0.87A | 1h4oB-4frzA:undetectable | 1h4oB-4frzA:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gxw | ADENOSINE DEAMINASE (Burkholderiaambifaria) |
PF00962(A_deaminase) | 4 | PRO A 9THR A 4PRO A 5GLY A 6 | None | 0.78A | 1h4oB-4gxwA:undetectable | 1h4oB-4gxwA:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k1f | TRYPAREDOXINPEROXIDASE (Leishmaniamajor) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 4 | PRO A 45THR A 49CYH A 52ARG A 128 | NonePGE A 201 ( 4.1A)NoneNone | 0.51A | 1h4oB-4k1fA:17.5 | 1h4oB-4k1fA:24.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lgm | VPS4 AAA ATPASE (Sulfolobussolfataricus) |
PF00004(AAA)PF09336(Vps4_C) | 4 | PRO A 273PRO A 143GLY A 144CYH A 145 | NoneNone CL A 401 ( 4.4A)None | 0.75A | 1h4oB-4lgmA:undetectable | 1h4oB-4lgmA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4llr | TRYPAREDOXINPEROXIDASE (Trypanosomacruzi) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 4 | PRO A 45THR A 49CYH A 52ARG A 128 | None | 0.48A | 1h4oB-4llrA:17.5 | 1h4oB-4llrA:27.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oj5 | TAILSPIKE PROTEIN (Escherichiavirus CBA120) |
no annotation | 5 | PRO A 480PRO A 538GLY A 506PHE A 493THR A 503 | None | 1.39A | 1h4oB-4oj5A:undetectable | 1h4oB-4oj5A:12.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p6v | NA(+)-TRANSLOCATINGNADH-QUINONEREDUCTASE SUBUNIT CNA(+)-TRANSLOCATINGNADH-QUINONEREDUCTASE SUBUNIT D (Vibriocholerae;Vibrio cholerae) |
PF04205(FMN_bind)PF02508(Rnf-Nqr) | 4 | THR C 173PRO C 174GLY C 175THR D 35 | FMN C 301 (-3.2A)NoneNoneNone | 0.77A | 1h4oB-4p6vC:undetectable | 1h4oB-4p6vC:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4piv | FATTY ACID SYNTHASE (Homo sapiens) |
PF08242(Methyltransf_12)PF08659(KR) | 5 | THR A1120PRO A1121GLY A1512PHE A1517THR A1230 | None | 1.33A | 1h4oB-4pivA:undetectable | 1h4oB-4pivA:13.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qbj | GLYCYLPEPTIDEN-TETRADECANOYLTRANSFERASE (Aspergillusfumigatus) |
PF01233(NMT)PF02799(NMT_C) | 4 | THR A 302PRO A 303GLY A 304THR A 368 | None | 0.71A | 1h4oB-4qbjA:undetectable | 1h4oB-4qbjA:18.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rul | DNA TOPOISOMERASE 1 (Escherichiacoli) |
PF01131(Topoisom_bac)PF01396(zf-C4_Topoisom)PF01751(Toprim)PF08272(Topo_Zn_Ribbon) | 4 | THR A 667GLY A 684CYH A 683THR A 688 | NoneNone ZN A1002 (-2.3A)None | 0.88A | 1h4oB-4rulA:undetectable | 1h4oB-4rulA:12.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c04 | PUTATIVEPEROXIREDOXIN MT2298 (Mycobacteriumtuberculosis) |
PF00578(AhpC-TSA) | 4 | PRO A 38THR A 42CYH A 45ARG A 116 | None | 0.51A | 1h4oB-5c04A:19.5 | 1h4oB-5c04A:23.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cg0 | BETA-GLUCOSIDASE (Spodopterafrugiperda) |
PF00232(Glyco_hydro_1) | 4 | THR A 184GLY A 243CYH A 242THR A 322 | None | 0.81A | 1h4oB-5cg0A:undetectable | 1h4oB-5cg0A:15.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5elx | ATP-DEPENDENT RNAHELICASE DBP5 (Saccharomycescerevisiae) |
PF00270(DEAD)PF00271(Helicase_C) | 4 | PRO A 198THR A 215PRO A 216GLY A 217 | U B 5 ( 4.3A) U B 5 ( 3.5A) U B 4 ( 3.8A) U B 5 ( 3.3A) | 0.61A | 1h4oB-5elxA:undetectable | 1h4oB-5elxA:17.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5enu | ALKYL HYDROPEROXIDEREDUCTASE/ THIOLSPECIFICANTIOXIDANT/ MALALLERGEN (Burkholderiaambifaria) |
PF00578(AhpC-TSA) | 6 | PRO A 37THR A 41PRO A 42GLY A 43CYH A 44ARG A 119 | None | 0.37A | 1h4oB-5enuA:19.1 | 1h4oB-5enuA:25.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5epf | PEROXIREDOXIN (Mycobacteriumtuberculosis) |
PF00578(AhpC-TSA) | 6 | PRO A 45THR A 49PRO A 50GLY A 51CYH A 52ARG A 124 | None | 0.92A | 1h4oB-5epfA:21.1 | 1h4oB-5epfA:28.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eqt | PROTEASOME-ACTIVATING NUCLEOTIDASE (Pyrococcushorikoshii) |
PF00004(AAA) | 4 | PRO A 277PRO A 149GLY A 150CYH A 151 | NoneACT A 402 ( 3.6A)ADP A 401 (-3.1A)None | 0.82A | 1h4oB-5eqtA:undetectable | 1h4oB-5eqtA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f0g | GLUTATHIONES-TRANSFERASE D2 (Drosophilamelanogaster) |
PF00043(GST_C)PF02798(GST_N) | 4 | THR A 190PRO A 191GLY A 192THR A 14 | None | 0.66A | 1h4oB-5f0gA:undetectable | 1h4oB-5f0gA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ghf | AMINOTRANSFERASECLASS-III (Ochrobactrumanthropi) |
PF00202(Aminotran_3) | 4 | PRO A 226THR A 267GLY A 263CYH A 262 | None | 0.88A | 1h4oB-5ghfA:undetectable | 1h4oB-5ghfA:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h7d | PUTRESCINEAMINOTRANSFERASE,IMMUNOGLOBULING-BINDING PROTEIN A (Escherichiacoli;Staphylococcusaureus) |
PF00202(Aminotran_3)PF02216(B) | 4 | THR A 137PRO A 138GLY A 139THR A 315 | None | 0.76A | 1h4oB-5h7dA:undetectable | 1h4oB-5h7dA:17.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ipg | BACTERIOFERRITINCOMIGRATORY PROTEIN (Xanthomonascampestris) |
PF00578(AhpC-TSA) | 6 | PRO A 41THR A 45PRO A 46GLY A 47CYH A 48ARG A 123 | None | 0.68A | 1h4oB-5ipgA:18.3 | 1h4oB-5ipgA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jcg | THIOREDOXIN-DEPENDENT PEROXIDEREDUCTASE,MITOCHONDRIAL (Homo sapiens) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 4 | PRO A 40THR A 44CYH A 47ARG A 123 | None | 0.54A | 1h4oB-5jcgA:17.7 | 1h4oB-5jcgA:27.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jri | PYRIDINENUCLEOTIDE-DISULFIDEOXIDOREDUCTASE (Synechocystissp. PCC 6803) |
no annotation | 4 | THR A 71PRO A 72GLY A 73THR A 78 | None | 0.87A | 1h4oB-5jriA:2.3 | 1h4oB-5jriA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jta | NEUTRAL TREHALASE (Saccharomycescerevisiae) |
no annotation | 5 | PRO A 271THR A 217PRO A 218GLY A 219ARG A 224 | None | 1.48A | 1h4oB-5jtaA:undetectable | 1h4oB-5jtaA:13.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5k1g | 1-CYS PEROXIREDOXIN (Vibriovulnificus) |
PF08534(Redoxin) | 5 | PRO A 41THR A 45PRO A 46PHE A 117ARG A 124 | None | 0.84A | 1h4oB-5k1gA:28.2 | 1h4oB-5k1gA:43.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kwa | PROTEASOME-ASSOCIATED ATPASE (Mycobacteriumtuberculosis) |
PF00004(AAA)PF16450(Prot_ATP_ID_OB) | 4 | PRO A 440PRO A 295GLY A 296CYH A 297 | NoneADP A 701 (-4.9A)ADP A 701 (-3.3A)None | 0.87A | 1h4oB-5kwaA:undetectable | 1h4oB-5kwaA:17.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o5d | GLUCANASE (Trichodermaatroviride) |
no annotation | 4 | PRO A 382THR A 389PRO A 390GLY A 391 | NoneNoneGOL A 609 ( 4.8A)GOL A 609 (-4.0A) | 0.84A | 1h4oB-5o5dA:undetectable | 1h4oB-5o5dA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tc1 | MATURATION PROTEIN (Escherichiavirus MS2) |
PF03863(Phage_mat-A) | 4 | THR M 40PRO M 41GLY M 42PHE M 4 | NoneNoneNone U R3553 ( 3.8A) | 0.81A | 1h4oB-5tc1M:undetectable | 1h4oB-5tc1M:18.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vk2 | PRE-GLYCOPROTEINPOLYPROTEIN GPCOMPLEX (Lassamammarenavirus) |
PF00798(Arena_glycoprot) | 4 | THR a 274PRO a 275GLY a 276THR a 296 | None | 0.79A | 1h4oB-5vk2a:undetectable | 1h4oB-5vk2a:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x3d | PHOSPHOENOLPYRUVATEPHOSPHOMUTASE (Streptomyceswedmorensis) |
PF01467(CTP_transf_like) | 4 | PRO A 17THR A 124PRO A 125GLY A 126 | None7XL A 201 (-4.4A)NoneNone | 0.66A | 1h4oB-5x3dA:undetectable | 1h4oB-5x3dA:24.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xbq | PEROXIREDOXIN (Pyrococcushorikoshii) |
no annotation | 4 | PRO A 39THR A 43PRO A 44ARG A 121 | OCS A 46 ( 3.3A)OCS A 46 ( 3.6A)NoneOCS A 46 ( 2.3A) | 0.48A | 1h4oB-5xbqA:18.2 | 1h4oB-5xbqA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6aun | PLA2G6, IPLA2BETA (Cricetulusgriseus) |
no annotation | 4 | THR A 345PRO A 346GLY A 347THR A 313 | None | 0.76A | 1h4oB-6aunA:undetectable | 1h4oB-6aunA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bdz | DISINTEGRIN ANDMETALLOPROTEINASEDOMAIN-CONTAININGPROTEIN 10 (Homo sapiens) |
no annotation | 4 | THR A 400PRO A 401GLY A 402THR A 422 | None | 0.87A | 1h4oB-6bdzA:undetectable | 1h4oB-6bdzA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eon | BETA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
no annotation | 4 | PRO A 55GLY A 578CYH A 579PHE A 305 | None | 0.84A | 1h4oB-6eonA:undetectable | 1h4oB-6eonA:13.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gww | PEROXIREDOXIN (Sulfolobusislandicus) |
no annotation | 4 | PRO A 42THR A 46PRO A 47ARG A 125 | CSO A 49 ( 4.0A)CSO A 49 ( 3.3A)NoneCSO A 49 ( 3.1A) | 0.52A | 1h4oB-6gwwA:18.3 | 1h4oB-6gwwA:undetectable |