SIMILAR PATTERNS OF AMINO ACIDS FOR 1GTI_D_CCSD47_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fzt | PHOSPHOGLYCERATEMUTASE (Schizosaccharomycespombe) |
PF00300(His_Phos_1) | 4 | THR A 27LEU A 99GLY A 101LYS A 104 | None | 0.74A | 1gtiD-1fztA:0.0 | 1gtiD-1fztA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1igo | FAMILY 11 XYLANASE (Bacillussubtilis) |
PF00457(Glyco_hydro_11) | 4 | THR A 178LEU A 180GLY A 51LEU A 205 | None | 1.07A | 1gtiD-1igoA:undetectable | 1gtiD-1igoA:17.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iuf | CENTROMERE ABP1PROTEIN (Schizosaccharomycespombe) |
PF03221(HTH_Tnp_Tc5) | 4 | LEU A 33GLY A 29LEU A 24TYR A 20 | None | 0.82A | 1gtiD-1iufA:undetectable | 1gtiD-1iufA:20.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lbk | GLUTATHIONES-TRANSFERASE CLASSPI CHIMAERA (CODA) (Homo sapiens) |
PF02798(GST_N)PF14497(GST_C_3) | 6 | TRP A 38LEU A 48GLY A 50LEU A 52LYS A 54TYR A 63 | GSH A 504 (-3.9A)NoneNoneGSH A 504 (-4.7A)NoneNone | 0.38A | 1gtiD-1lbkA:33.3 | 1gtiD-1lbkA:82.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q2e | EXOCELLOBIOHYDROLASEI (Trichodermareesei) |
PF00840(Glyco_hydro_7) | 5 | THR A 5LEU A 73GLY A 75LYS A 166TYR A 167 | NonePCA A 1 ( 4.9A)NoneNoneNone | 1.39A | 1gtiD-1q2eA:0.0 | 1gtiD-1q2eA:18.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q2l | PROTEASE III (Escherichiacoli) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C)PF16187(Peptidase_M16_M) | 4 | LEU A 323GLY A 316LEU A 314TYR A 375 | None | 1.06A | 1gtiD-1q2lA:undetectable | 1gtiD-1q2lA:13.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u3i | GLUTATHIONES-TRANSFERASE 28 KDA (Schistosomamansoni) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TRP A 41THR A 47GLY A 51LEU A 53 | GSH A 301 (-4.0A)NoneNoneGSH A 301 (-4.4A) | 0.56A | 1gtiD-1u3iA:22.8 | 1gtiD-1u3iA:28.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u6g | TIP120 PROTEIN (Homo sapiens) |
PF08623(TIP120) | 4 | LEU C 851GLY C 853LEU C 855LYS C 858 | None | 0.91A | 1gtiD-1u6gC:2.9 | 1gtiD-1u6gC:10.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yw4 | SUCCINYLGLUTAMATEDESUCCINYLASE (Chromobacteriumviolaceum) |
PF04952(AstE_AspA) | 4 | THR A 71LEU A 78GLY A 76LEU A 23 | None | 1.03A | 1gtiD-1yw4A:undetectable | 1gtiD-1yw4A:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aml | SIS DOMAIN PROTEIN (Listeriamonocytogenes) |
PF01380(SIS) | 4 | TRP A 41LEU A 160GLY A 162LEU A 30 | None | 0.91A | 1gtiD-2amlA:1.0 | 1gtiD-2amlA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2arz | HYPOTHETICAL PROTEINPA4388 (Pseudomonasaeruginosa) |
PF10615(DUF2470)PF13883(Pyrid_oxidase_2) | 4 | LEU A 211GLY A 199LEU A 14LYS A 15 | None | 1.06A | 1gtiD-2arzA:undetectable | 1gtiD-2arzA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c2g | THREONINE SYNTHASE (Arabidopsisthaliana) |
PF00291(PALP) | 4 | TRP A 108LEU A 268GLY A 270LEU A 115 | None | 0.96A | 1gtiD-2c2gA:undetectable | 1gtiD-2c2gA:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cai | GLUTATHIONES-TRANSFERASE 28 KDA (Schistosomahaematobium) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | TRP A 41THR A 47GLY A 51LEU A 53 | None | 0.67A | 1gtiD-2caiA:20.8 | 1gtiD-2caiA:26.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cwa | SINGLE-STRANDBINDING PROTEIN (Thermusthermophilus) |
PF00436(SSB) | 4 | TRP A 52THR A 33GLY A 12LEU A 10 | None | 1.00A | 1gtiD-2cwaA:undetectable | 1gtiD-2cwaA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ddh | ACYL-COA OXIDASE (Rattusnorvegicus) |
PF01756(ACOX)PF02770(Acyl-CoA_dh_M)PF14749(Acyl-CoA_ox_N) | 4 | THR A 110LEU A 108GLY A 105LEU A 102 | NoneNoneNoneFAD A 699 (-4.4A) | 1.03A | 1gtiD-2ddhA:undetectable | 1gtiD-2ddhA:16.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dj0 | THIOREDOXIN-RELATEDTRANSMEMBRANEPROTEIN 2 (Homo sapiens) |
PF00085(Thioredoxin) | 4 | LEU A 128GLY A 133LYS A 54TYR A 55 | None | 1.03A | 1gtiD-2dj0A:undetectable | 1gtiD-2dj0A:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f9r | SPHINGOMYELINASE D 1 (Loxosceleslaeta) |
no annotation | 4 | LEU A 242GLY A 245LYS A 269TYR A 270 | None | 0.95A | 1gtiD-2f9rA:undetectable | 1gtiD-2f9rA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fiy | PROTEIN FDHE HOMOLOG (Pseudomonasaeruginosa) |
PF04216(FdhE) | 4 | LEU A 290GLY A 294LEU A 296TYR A 262 | None | 1.04A | 1gtiD-2fiyA:undetectable | 1gtiD-2fiyA:22.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2gsr | CLASS PI GSTGLUTATHIONES-TRANSFERASE (Sus scrofa) |
PF02798(GST_N)PF14497(GST_C_3) | 5 | TRP A 38LEU A 46LEU A 50LYS A 52TYR A 61 | GTS A 208 (-3.9A)NoneGTS A 208 (-4.8A)NoneNone | 0.39A | 1gtiD-2gsrA:34.8 | 1gtiD-2gsrA:84.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ipc | PREPROTEINTRANSLOCASE SECASUBUNIT (Thermusthermophilus) |
PF01043(SecA_PP_bind)PF07516(SecA_SW)PF07517(SecA_DEAD) | 4 | THR A 110LEU A 115GLY A 88LEU A 85 | None | 1.05A | 1gtiD-2ipcA:undetectable | 1gtiD-2ipcA:12.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nz9 | BOTULINUM NEUROTOXINTYPE A (Clostridiumbotulinum) |
PF01742(Peptidase_M27)PF07951(Toxin_R_bind_C)PF07952(Toxin_trans)PF07953(Toxin_R_bind_N) | 4 | THR A 109LEU A 107GLY A 104TYR A 349 | None | 1.00A | 1gtiD-2nz9A:undetectable | 1gtiD-2nz9A:9.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wsc | PHOTOSYSTEM IREACTION CENTERSUBUNIT VI,CHLOROPLASTIC (Spinaciaoleracea) |
PF03244(PSI_PsaH) | 4 | THR H 66LEU H 64GLY H 61LEU H 59 | NoneCLA H1079 ( 3.9A)NoneNone | 1.05A | 1gtiD-2wscH:undetectable | 1gtiD-2wscH:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wu8 | GLUCOSE-6-PHOSPHATEISOMERASE (Mycobacteriumtuberculosis) |
PF00342(PGI) | 4 | THR A 203LEU A 205GLY A 143LEU A 233 | None | 0.90A | 1gtiD-2wu8A:undetectable | 1gtiD-2wu8A:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ww9 | SEC SIXTY-ONEPROTEIN HOMOLOG (Saccharomycescerevisiae) |
PF00344(SecY)PF10559(Plug_translocon) | 4 | THR A 164GLY A 159LEU A 157TYR A 128 | None | 1.04A | 1gtiD-2ww9A:undetectable | 1gtiD-2ww9A:17.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xi7 | RNA POLYMERASE L (Californiaencephalitisorthobunyavirus) |
PF15518(L_protein_N) | 4 | THR A 77LEU A 112LYS A 108TYR A 109 | None | 1.06A | 1gtiD-2xi7A:undetectable | 1gtiD-2xi7A:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yok | EXOGLUCANASE 1 (Trichodermaharzianum) |
PF00840(Glyco_hydro_7) | 5 | THR A 22LEU A 89GLY A 91LYS A 179TYR A 180 | NonePCA A 18 ( 4.5A)NoneNoneNone | 1.44A | 1gtiD-2yokA:undetectable | 1gtiD-2yokA:18.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yqu | 2-OXOGLUTARATEDEHYDROGENASE E3COMPONENT (Thermusthermophilus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | THR A 227LEU A 196GLY A 174LEU A 180 | None | 1.01A | 1gtiD-2yquA:undetectable | 1gtiD-2yquA:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a74 | LYSYL-TRNASYNTHETASE (Geobacillusstearothermophilus) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon) | 4 | LEU A 188GLY A 192LEU A 194TYR A 246 | None | 0.90A | 1gtiD-3a74A:undetectable | 1gtiD-3a74A:16.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cux | MALATE SYNTHASE (Bacillusanthracis) |
PF01274(Malate_synthase) | 4 | TRP A 363GLY A 272LEU A 245LYS A 212 | NoneNone MG A 1 ( 4.9A) MG A 1 ( 4.2A) | 0.85A | 1gtiD-3cuxA:undetectable | 1gtiD-3cuxA:17.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d46 | PUTATIVE GALACTONATEDEHYDRATASE (Salmonellaenterica) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 384LEU A 154LYS A 158TYR A 157 | None | 1.06A | 1gtiD-3d46A:undetectable | 1gtiD-3d46A:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gnn | NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE (Burkholderiapseudomallei) |
PF01729(QRPTase_C)PF02749(QRPTase_N) | 4 | LEU A 152GLY A 154LEU A 157LYS A 160 | None | 0.94A | 1gtiD-3gnnA:undetectable | 1gtiD-3gnnA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i04 | CARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT BETA (Moorellathermoacetica) |
PF03063(Prismane) | 4 | THR A 318LEU A 323GLY A 314LEU A 312 | None | 1.02A | 1gtiD-3i04A:undetectable | 1gtiD-3i04A:13.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m4a | PUTATIVE TYPE ITOPOISOMERASE (Deinococcusradiodurans) |
PF01028(Topoisom_I) | 4 | THR A 322LEU A 318GLY A 320LEU A 102 | None | 1.01A | 1gtiD-3m4aA:undetectable | 1gtiD-3m4aA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n2t | PUTATIVEOXIDOREDUCTASE (Gluconobacteroxydans) |
PF00248(Aldo_ket_red) | 4 | TRP A 23LEU A 183GLY A 209LEU A 281 | None | 0.70A | 1gtiD-3n2tA:undetectable | 1gtiD-3n2tA:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nrn | UNCHARACTERIZEDPROTEIN PF1083 (Pyrococcusfuriosus) |
PF01593(Amino_oxidase) | 4 | THR A 208LEU A 29GLY A 7LEU A 13 | NoneNoneAMP A 422 (-3.2A)None | 1.04A | 1gtiD-3nrnA:undetectable | 1gtiD-3nrnA:21.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3o76 | GLUTATHIONES-TRANSFERASE P 1 (Mus musculus) |
PF02798(GST_N)PF14497(GST_C_3) | 7 | TRP A 38THR A 46LEU A 48GLY A 50LEU A 52LYS A 54TYR A 63 | GTB A 210 (-4.0A)NoneNoneNoneGTB A 210 (-4.9A)NoneNone | 0.42A | 1gtiD-3o76A:34.9 | 1gtiD-3o76A:99.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3omv | RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE (Homo sapiens) |
PF07714(Pkinase_Tyr) | 4 | TRP A 423THR A 353LEU A 351GLY A 366 | SM5 A 1 (-4.3A)NoneNoneNone | 0.99A | 1gtiD-3omvA:undetectable | 1gtiD-3omvA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p54 | ENVELOPEGLYCOPROTEIN (Japaneseencephalitisvirus) |
PF00869(Flavi_glycoprot)PF02832(Flavi_glycop_C) | 4 | LEU A 285GLY A 283LEU A 280TYR A 137 | None | 0.94A | 1gtiD-3p54A:undetectable | 1gtiD-3p54A:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qtg | PYRUVATE KINASE (Pyrobaculumaerophilum) |
PF00224(PK)PF02887(PK_C) | 4 | THR A 276LEU A 278GLY A 281LEU A 354 | None | 1.00A | 1gtiD-3qtgA:undetectable | 1gtiD-3qtgA:18.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rr6 | PUTATIVEUNCHARACTERIZEDPROTEIN (Mycobacteroidesabscessus) |
PF01557(FAA_hydrolase)PF10370(DUF2437) | 4 | LEU A 178GLY A 139LEU A 3LYS A 1 | None | 0.96A | 1gtiD-3rr6A:undetectable | 1gtiD-3rr6A:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3stj | PROTEASE DEGQ (Escherichiacoli) |
PF13180(PDZ_2)PF13365(Trypsin_2) | 4 | THR A 203LEU A 191GLY A 189LEU A 78 | None | 0.96A | 1gtiD-3stjA:undetectable | 1gtiD-3stjA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3td7 | FAD-LINKEDSULFHYDRYL OXIDASER596 (Acanthamoebapolyphagamimivirus) |
PF04777(Evr1_Alr) | 4 | THR A 207LEU A 209GLY A 211LEU A 265 | None | 1.07A | 1gtiD-3td7A:undetectable | 1gtiD-3td7A:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vml | 3-ISOPROPYLMALATEDEHYDROGENASE (Shewanellabenthica;Shewanellaoneidensis) |
PF00180(Iso_dh) | 4 | LEU A 246GLY A 248LEU A 138TYR A 143 | CL A 403 (-4.6A)NoneNoneIPM A 401 (-4.5A) | 1.03A | 1gtiD-3vmlA:undetectable | 1gtiD-3vmlA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vr1 | PEPTIDE CHAINRELEASE FACTOR 3 (Desulfovibriovulgaris) |
PF00009(GTP_EFTU)PF03144(GTP_EFTU_D2)PF16658(RF3_C) | 4 | THR A 134LEU A 245GLY A 247TYR A 244 | None | 0.98A | 1gtiD-3vr1A:undetectable | 1gtiD-3vr1A:16.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wsy | SORTILIN-RELATEDRECEPTOR (Homo sapiens) |
PF15901(Sortilin_C)PF15902(Sortilin-Vps10) | 4 | LEU A 745GLY A 747LYS A 730TYR A 682 | None | 0.98A | 1gtiD-3wsyA:undetectable | 1gtiD-3wsyA:16.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zok | 3-DEHYDROQUINATESYNTHASE (Actinidiachinensis) |
PF01761(DHQ_synthase) | 4 | THR A 144LEU A 192GLY A 195LEU A 277 | NAD A1381 (-3.5A)NoneNoneNone | 0.98A | 1gtiD-3zokA:undetectable | 1gtiD-3zokA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4av6 | K(+)-STIMULATEDPYROPHOSPHATE-ENERGIZED SODIUM PUMP (Thermotogamaritima) |
PF03030(H_PPase) | 4 | TRP A 659THR A 652GLY A 413LEU A 410 | None | 0.96A | 1gtiD-4av6A:1.2 | 1gtiD-4av6A:14.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c6o | CAD PROTEIN (Homo sapiens) |
PF01979(Amidohydro_1) | 4 | TRP A1581THR A1547GLY A1550LEU A1535 | None | 0.89A | 1gtiD-4c6oA:undetectable | 1gtiD-4c6oA:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4chl | PERSULFIDEDIOXYGENASE ETHE1,MITOCHONDRIAL (Homo sapiens) |
PF00753(Lactamase_B) | 4 | THR A 57LEU A 90GLY A 87LEU A 50 | None | 1.04A | 1gtiD-4chlA:undetectable | 1gtiD-4chlA:26.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cns | DIHYDROPYRIMIDINASE-LIKE 3 (Homo sapiens) |
PF01979(Amidohydro_1) | 4 | THR A 384LEU A 328GLY A 330LEU A 283 | None | 0.97A | 1gtiD-4cnsA:undetectable | 1gtiD-4cnsA:16.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cnt | DIHYDROPYRIMIDINASE-LIKE 3 (Homo sapiens) |
PF01979(Amidohydro_1) | 4 | THR A 384LEU A 328GLY A 330LEU A 283 | None | 0.94A | 1gtiD-4cntA:undetectable | 1gtiD-4cntA:18.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cuo | BANYAN PEROXIDASE (Ficusbenghalensis) |
PF00141(peroxidase) | 4 | THR A 245GLY A 241LEU A 220TYR A 232 | HEM A1307 (-3.5A)NoneNoneNone | 0.82A | 1gtiD-4cuoA:undetectable | 1gtiD-4cuoA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cza | NA+/H+ ANTIPORTER,PUTATIVE (Pyrococcusabyssi) |
PF00999(Na_H_Exchanger) | 4 | GLY A 266LEU A 270LYS A 269TYR A 268 | None | 1.07A | 1gtiD-4czaA:undetectable | 1gtiD-4czaA:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dje | CORRINOID/IRON-SULFUR PROTEIN SMALLSUBUNIT (Moorellathermoacetica) |
PF03599(CdhD) | 4 | LEU D 300GLY D 254LYS D 101TYR D 99 | None | 0.97A | 1gtiD-4djeD:undetectable | 1gtiD-4djeD:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dpg | LYSINE--TRNA LIGASE (Homo sapiens) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon) | 4 | LEU A 258GLY A 262LEU A 264TYR A 316 | None | 0.95A | 1gtiD-4dpgA:undetectable | 1gtiD-4dpgA:18.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f92 | U5 SMALL NUCLEARRIBONUCLEOPROTEIN200 KDA HELICASE (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C)PF02889(Sec63) | 4 | TRP B1652THR B1352LEU B1490LEU B1458 | None | 0.99A | 1gtiD-4f92B:undetectable | 1gtiD-4f92B:8.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fsp | PROBABLE PORIN (Pseudomonasaeruginosa) |
PF03573(OprD) | 4 | THR A 135LEU A 146GLY A 185LEU A 114 | NoneNoneC8E A 406 ( 4.0A)None | 0.94A | 1gtiD-4fspA:undetectable | 1gtiD-4fspA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gqy | CBSDOMAIN-CONTAININGPROTEIN CBSX2,CHLOROPLASTIC (Arabidopsisthaliana) |
PF00571(CBS) | 4 | THR A 178LEU A 176GLY A 174LYS A 163 | AMP A 301 (-3.4A)NoneNoneNone | 1.06A | 1gtiD-4gqyA:undetectable | 1gtiD-4gqyA:23.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j2u | ENOYL-COA HYDRATASE (Rhodobactersphaeroides) |
PF16113(ECH_2) | 4 | THR A 110LEU A 23GLY A 63LEU A 26 | None | 0.88A | 1gtiD-4j2uA:undetectable | 1gtiD-4j2uA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kk2 | MONOTERPENE SYNTHASEFDS-5, CHLOROPLASTIC- FARNESYLDIPHOSPHATE SYNTHASE1 CHIMERA (Artemisiaspiciformis) |
PF00348(polyprenyl_synt) | 4 | LEU A 209GLY A 212LYS A 144TYR A 146 | None | 1.01A | 1gtiD-4kk2A:undetectable | 1gtiD-4kk2A:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4psp | ALPHA-FUCOSIDASEGH29 (Fusariumgraminearum) |
PF01120(Alpha_L_fucos)PF16757(Fucosidase_C) | 4 | GLY A 370LEU A 451LYS A 488TYR A 417 | None | 0.94A | 1gtiD-4pspA:undetectable | 1gtiD-4pspA:14.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qts | CRISPR TYPEIII-ASSOCIATED RAMPPROTEIN CSM4 (Methanocaldococcusjannaschii) |
PF03787(RAMPs) | 4 | LEU A 50GLY A 46LYS A 220TYR A 41 | None | 1.06A | 1gtiD-4qtsA:undetectable | 1gtiD-4qtsA:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qvg | SIBL (Streptosporangiumsibiricum) |
PF00891(Methyltransf_2)PF16864(Dimerisation2) | 4 | THR A 63LEU A 67GLY A 78LEU A 33 | None | 0.90A | 1gtiD-4qvgA:undetectable | 1gtiD-4qvgA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rew | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-1 (Homo sapiens) |
PF00069(Pkinase)PF16579(AdenylateSensor) | 4 | THR A 174GLY A 189LEU A 191TYR A 192 | None | 1.04A | 1gtiD-4rewA:undetectable | 1gtiD-4rewA:17.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tx2 | NON-RIBOSOMALPEPTIDE SYNTHETASE (Actinoplanesteichomyceticus) |
PF00668(Condensation) | 4 | THR B 285LEU B 363GLY B 283LEU B 395 | None | 0.96A | 1gtiD-4tx2B:undetectable | 1gtiD-4tx2B:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4up7 | LYSINE--TRNA LIGASE (Entamoebahistolytica) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon) | 4 | LEU A 186GLY A 190LEU A 192TYR A 244 | None | 0.99A | 1gtiD-4up7A:undetectable | 1gtiD-4up7A:15.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v36 | LYSYL-TRNA-DEPENDENTL-YSYL-PHOSPHATIDYLGYCEROL SYNTHASE (Bacilluslicheniformis) |
PF09924(DUF2156) | 4 | THR A 842LEU A 844GLY A 846LEU A 698 | NoneNoneNoneLYN A1851 ( 4.3A) | 1.04A | 1gtiD-4v36A:undetectable | 1gtiD-4v36A:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v3i | VCA0115 (Vibrio cholerae) |
PF09850(DotU) | 4 | THR A 44LEU A 46GLY A 48LEU A 162 | None | 1.00A | 1gtiD-4v3iA:undetectable | 1gtiD-4v3iA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wbo | RHODOPSIN KINASE (Bos taurus) |
PF00069(Pkinase)PF00615(RGS) | 4 | TRP A 174THR A 522GLY A 526LEU A 528 | None | 1.02A | 1gtiD-4wboA:undetectable | 1gtiD-4wboA:17.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wj3 | ASPARTATE--TRNA(ASP/ASN) LIGASE (Pseudomonasaeruginosa) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon)PF02938(GAD) | 4 | LEU M 155GLY M 159LEU M 161TYR M 213 | None | 1.06A | 1gtiD-4wj3M:undetectable | 1gtiD-4wj3M:17.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xk8 | PUTATIVEUNCHARACTERIZEDPROTEIN (Pisum sativum) |
PF02605(PsaL) | 4 | THR L 136LEU L 46GLY L 49LEU L 126 | None | 1.03A | 1gtiD-4xk8L:undetectable | 1gtiD-4xk8L:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y4n | PUTATIVE RIBOSE1,5-BISPHOSPHATEISOMERASE (Methanotorrisigneus) |
PF01946(Thi4) | 4 | THR A 129LEU A 58GLY A 36LEU A 42 | NoneNone48H A 302 (-3.2A)None | 0.98A | 1gtiD-4y4nA:undetectable | 1gtiD-4y4nA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bza | BETA-N-ACETYLHEXOSAMINIDASE (Thermotoganeapolitana) |
PF00933(Glyco_hydro_3) | 4 | THR A 204LEU A 241GLY A 240LEU A 232 | None | 0.91A | 1gtiD-5bzaA:undetectable | 1gtiD-5bzaA:15.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d1r | RV1816TRANSCRIPTIONALREGULATOR (Mycobacteriumtuberculosis) |
PF00440(TetR_N) | 4 | TRP A 91THR A 224LEU A 226LEU A 231 | None | 1.01A | 1gtiD-5d1rA:undetectable | 1gtiD-5d1rA:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dcq | FIBRONECTIN-BINDINGPROTEIN (Streptococcusequi) |
PF08341(TED) | 4 | LEU D 66LEU D 2LYS D 23TYR D 4 | None | 1.04A | 1gtiD-5dcqD:undetectable | 1gtiD-5dcqD:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e9h | ISOCITRATE LYASE (Fusariumgraminearum) |
PF00463(ICL) | 4 | THR A 186LEU A 191GLY A 183TYR A 129 | None | 1.05A | 1gtiD-5e9hA:undetectable | 1gtiD-5e9hA:16.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ejy | MYOSIN-I HEAVY CHAIN (Dictyosteliumdiscoideum) |
PF00784(MyTH4) | 4 | LEU A 468GLY A 472LEU A 535TYR A 531 | None | 1.06A | 1gtiD-5ejyA:undetectable | 1gtiD-5ejyA:17.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eks | 3-DEHYDROQUINATESYNTHASE (Acinetobacterbaumannii) |
PF01761(DHQ_synthase) | 4 | THR A 129LEU A 177GLY A 180LEU A 262 | NAD A 400 (-2.7A)NoneNoneNone | 0.99A | 1gtiD-5eksA:undetectable | 1gtiD-5eksA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eo7 | PREDICTED PROTEIN (Aspergillusoryzae) |
PF07938(Fungal_lectin) | 4 | TRP A 271THR A 293LEU A 278LEU A 24 | NoneSFU A 405 ( 4.1A)NoneSFU A 405 ( 4.1A) | 1.07A | 1gtiD-5eo7A:undetectable | 1gtiD-5eo7A:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f7u | CYCLOALTERNAN-FORMING ENZYME (Listeriamonocytogenes) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF16338(DUF4968)PF16990(CBM_35) | 4 | THR A 128GLY A 126LYS A 33TYR A 134 | None | 1.04A | 1gtiD-5f7uA:undetectable | 1gtiD-5f7uA:11.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fzp | DISPASEAUTOLYSIS-INDUCINGPROTEIN (Streptomycesmobaraensis) |
no annotation | 4 | TRP A 201THR A 171GLY A 143LEU A 145 | None | 1.01A | 1gtiD-5fzpA:undetectable | 1gtiD-5fzpA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gv1 | ENDO-1,4-BETA-XYLANASE (termite gutmetagenome) |
PF00457(Glyco_hydro_11) | 4 | LEU A 23GLY A 25LYS A 73TYR A 62 | None | 1.05A | 1gtiD-5gv1A:undetectable | 1gtiD-5gv1A:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hgq | LYSINE--TRNA LIGASE (Loa loa) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon) | 4 | LEU A 190GLY A 194LEU A 196TYR A 248 | None | 1.02A | 1gtiD-5hgqA:undetectable | 1gtiD-5hgqA:17.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i67 | PHOSPHOENOLPYRUVATECARBOXYKINASE [GTP] (Mycobacteriumtuberculosis) |
PF00821(PEPCK_C)PF17297(PEPCK_N) | 4 | GLY A 408LEU A 293LYS A 254TYR A 264 | PEG A 702 ( 4.8A)NoneNoneNone | 0.94A | 1gtiD-5i67A:undetectable | 1gtiD-5i67A:15.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iso | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homo sapiens) |
PF00069(Pkinase)PF16579(AdenylateSensor) | 4 | THR A 172GLY A 187LEU A 189TYR A 190 | None | 0.98A | 1gtiD-5isoA:undetectable | 1gtiD-5isoA:14.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j1i | PLECTIN (Homo sapiens) |
no annotation | 4 | TRP A1249THR A1354LEU A1356LEU A1250 | None | 1.05A | 1gtiD-5j1iA:undetectable | 1gtiD-5j1iA:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jd8 | PERIPLASMIC SERINEPEPTIDASE DEGS (Yersinia pestis) |
PF13180(PDZ_2)PF13365(Trypsin_2) | 4 | THR A 216LEU A 204GLY A 202LEU A 92 | None | 1.04A | 1gtiD-5jd8A:undetectable | 1gtiD-5jd8A:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lki | TCDA1 (Photorhabdusluminescens) |
PF03538(VRP1) | 4 | LEU A2375GLY A2369LEU A2344TYR A2341 | None | 0.90A | 1gtiD-5lkiA:undetectable | 1gtiD-5lkiA:6.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5min | QUINOPROTEIN GLUCOSEDEHYDROGENASE B (Acinetobactercalcoaceticus) |
no annotation | 4 | THR A 194LEU A 225GLY A 197LEU A 200 | None | 1.05A | 1gtiD-5minA:undetectable | 1gtiD-5minA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u84 | ACID CERAMIDASE (Balaenopteraacutorostrata) |
no annotation | 4 | TRP A 62LEU A 211GLY A 209LEU A 189 | None | 1.07A | 1gtiD-5u84A:undetectable | 1gtiD-5u84A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ufv | GLYCOSIDE HYDROLASEFAMILY 61 PROTEIN (Thermothelomycesthermophila) |
PF03443(Glyco_hydro_61) | 4 | THR A 74LEU A 131GLY A 134LYS A 2 | HIC A 1 (-3.7A)NoneNoneHIC A 1 ( 3.6A) | 0.89A | 1gtiD-5ufvA:undetectable | 1gtiD-5ufvA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uj7 | ORIGIN RECOGNITIONCOMPLEX SUBUNIT 5 (Homo sapiens) |
PF13191(AAA_16)PF14630(ORC5_C) | 4 | THR E 39GLY E 37LEU E 157LYS E 126 | ATP E 301 (-3.9A)NoneNoneATP E 301 ( 3.7A) | 0.87A | 1gtiD-5uj7E:undetectable | 1gtiD-5uj7E:23.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ujm | ORIGIN RECOGNITIONCOMPLEX SUBUNIT 5 (Homo sapiens) |
PF13191(AAA_16)PF14630(ORC5_C) | 4 | THR E 39GLY E 37LEU E 157LYS E 126 | ATP E 501 (-3.9A)NoneNoneATP E 501 ( 3.7A) | 0.87A | 1gtiD-5ujmE:undetectable | 1gtiD-5ujmE:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vbb | RNA PSEUDOURIDYLATESYNTHASEDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF00849(PseudoU_synth_2) | 4 | GLY A 72LEU A 213LYS A 97TYR A 99 | NoneNoneGOL A 306 (-3.1A)GOL A 306 (-3.8A) | 0.88A | 1gtiD-5vbbA:undetectable | 1gtiD-5vbbA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w21 | KLOTHO (Homo sapiens) |
no annotation | 4 | THR A 810LEU A 852GLY A 851TYR A 894 | None | 1.06A | 1gtiD-5w21A:undetectable | 1gtiD-5w21A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xg2 | CHROMOSOME PARTITIONPROTEIN SMC (Pyrococcusyayanosii) |
PF05483(SCP-1) | 4 | THR A 393LEU A 398LEU A 771LYS A 767 | None | 0.90A | 1gtiD-5xg2A:undetectable | 1gtiD-5xg2A:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xqo | PCRGLX PROTEIN (Penicilliumchrysogenum) |
no annotation | 4 | TRP A 89LEU A 504GLY A 47LEU A 661 | None | 0.78A | 1gtiD-5xqoA:1.4 | 1gtiD-5xqoA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6chd | LYSINE--TRNA LIGASE (Homo sapiens) |
no annotation | 4 | LEU A 258GLY A 262LEU A 264TYR A 316 | None | 0.92A | 1gtiD-6chdA:undetectable | 1gtiD-6chdA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d9z | SULFATE TRANSPORTERCYSZ (Pseudomonasdenitrificans(nomenrejiciendum)) |
no annotation | 4 | LEU F 10GLY F 230LEU F 16LYS F 15 | None | 0.89A | 1gtiD-6d9zF:undetectable | 1gtiD-6d9zF:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fml | INO80 (Chaetomiumthermophilum) |
no annotation | 4 | TRP G 982LEU G1133GLY G 993LEU G 983 | None | 0.97A | 1gtiD-6fmlG:undetectable | 1gtiD-6fmlG:undetectable |