SIMILAR PATTERNS OF AMINO ACIDS FOR 1GTI_D_CCSD47_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fzt PHOSPHOGLYCERATE
MUTASE


(Schizosaccharomyces
pombe)
PF00300
(His_Phos_1)
4 THR A  27
LEU A  99
GLY A 101
LYS A 104
None
0.74A 1gtiD-1fztA:
0.0
1gtiD-1fztA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1igo FAMILY 11 XYLANASE

(Bacillus
subtilis)
PF00457
(Glyco_hydro_11)
4 THR A 178
LEU A 180
GLY A  51
LEU A 205
None
1.07A 1gtiD-1igoA:
undetectable
1gtiD-1igoA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iuf CENTROMERE ABP1
PROTEIN


(Schizosaccharomyces
pombe)
PF03221
(HTH_Tnp_Tc5)
4 LEU A  33
GLY A  29
LEU A  24
TYR A  20
None
0.82A 1gtiD-1iufA:
undetectable
1gtiD-1iufA:
20.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lbk GLUTATHIONE
S-TRANSFERASE CLASS
PI CHIMAERA (CODA)


(Homo sapiens)
PF02798
(GST_N)
PF14497
(GST_C_3)
6 TRP A  38
LEU A  48
GLY A  50
LEU A  52
LYS A  54
TYR A  63
GSH  A 504 (-3.9A)
None
None
GSH  A 504 (-4.7A)
None
None
0.38A 1gtiD-1lbkA:
33.3
1gtiD-1lbkA:
82.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q2e EXOCELLOBIOHYDROLASE
I


(Trichoderma
reesei)
PF00840
(Glyco_hydro_7)
5 THR A   5
LEU A  73
GLY A  75
LYS A 166
TYR A 167
None
PCA  A   1 ( 4.9A)
None
None
None
1.39A 1gtiD-1q2eA:
0.0
1gtiD-1q2eA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q2l PROTEASE III

(Escherichia
coli)
PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF16187
(Peptidase_M16_M)
4 LEU A 323
GLY A 316
LEU A 314
TYR A 375
None
1.06A 1gtiD-1q2lA:
undetectable
1gtiD-1q2lA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u3i GLUTATHIONE
S-TRANSFERASE 28 KDA


(Schistosoma
mansoni)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 TRP A  41
THR A  47
GLY A  51
LEU A  53
GSH  A 301 (-4.0A)
None
None
GSH  A 301 (-4.4A)
0.56A 1gtiD-1u3iA:
22.8
1gtiD-1u3iA:
28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u6g TIP120 PROTEIN

(Homo sapiens)
PF08623
(TIP120)
4 LEU C 851
GLY C 853
LEU C 855
LYS C 858
None
0.91A 1gtiD-1u6gC:
2.9
1gtiD-1u6gC:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yw4 SUCCINYLGLUTAMATE
DESUCCINYLASE


(Chromobacterium
violaceum)
PF04952
(AstE_AspA)
4 THR A  71
LEU A  78
GLY A  76
LEU A  23
None
1.03A 1gtiD-1yw4A:
undetectable
1gtiD-1yw4A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aml SIS DOMAIN PROTEIN

(Listeria
monocytogenes)
PF01380
(SIS)
4 TRP A  41
LEU A 160
GLY A 162
LEU A  30
None
0.91A 1gtiD-2amlA:
1.0
1gtiD-2amlA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2arz HYPOTHETICAL PROTEIN
PA4388


(Pseudomonas
aeruginosa)
PF10615
(DUF2470)
PF13883
(Pyrid_oxidase_2)
4 LEU A 211
GLY A 199
LEU A  14
LYS A  15
None
1.06A 1gtiD-2arzA:
undetectable
1gtiD-2arzA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c2g THREONINE SYNTHASE

(Arabidopsis
thaliana)
PF00291
(PALP)
4 TRP A 108
LEU A 268
GLY A 270
LEU A 115
None
0.96A 1gtiD-2c2gA:
undetectable
1gtiD-2c2gA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cai GLUTATHIONE
S-TRANSFERASE 28 KDA


(Schistosoma
haematobium)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 TRP A  41
THR A  47
GLY A  51
LEU A  53
None
0.67A 1gtiD-2caiA:
20.8
1gtiD-2caiA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cwa SINGLE-STRAND
BINDING PROTEIN


(Thermus
thermophilus)
PF00436
(SSB)
4 TRP A  52
THR A  33
GLY A  12
LEU A  10
None
1.00A 1gtiD-2cwaA:
undetectable
1gtiD-2cwaA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ddh ACYL-COA OXIDASE

(Rattus
norvegicus)
PF01756
(ACOX)
PF02770
(Acyl-CoA_dh_M)
PF14749
(Acyl-CoA_ox_N)
4 THR A 110
LEU A 108
GLY A 105
LEU A 102
None
None
None
FAD  A 699 (-4.4A)
1.03A 1gtiD-2ddhA:
undetectable
1gtiD-2ddhA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dj0 THIOREDOXIN-RELATED
TRANSMEMBRANE
PROTEIN 2


(Homo sapiens)
PF00085
(Thioredoxin)
4 LEU A 128
GLY A 133
LYS A  54
TYR A  55
None
1.03A 1gtiD-2dj0A:
undetectable
1gtiD-2dj0A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f9r SPHINGOMYELINASE D 1

(Loxosceles
laeta)
no annotation 4 LEU A 242
GLY A 245
LYS A 269
TYR A 270
None
0.95A 1gtiD-2f9rA:
undetectable
1gtiD-2f9rA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fiy PROTEIN FDHE HOMOLOG

(Pseudomonas
aeruginosa)
PF04216
(FdhE)
4 LEU A 290
GLY A 294
LEU A 296
TYR A 262
None
1.04A 1gtiD-2fiyA:
undetectable
1gtiD-2fiyA:
22.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gsr CLASS PI GST
GLUTATHIONE
S-TRANSFERASE


(Sus scrofa)
PF02798
(GST_N)
PF14497
(GST_C_3)
5 TRP A  38
LEU A  46
LEU A  50
LYS A  52
TYR A  61
GTS  A 208 (-3.9A)
None
GTS  A 208 (-4.8A)
None
None
0.39A 1gtiD-2gsrA:
34.8
1gtiD-2gsrA:
84.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ipc PREPROTEIN
TRANSLOCASE SECA
SUBUNIT


(Thermus
thermophilus)
PF01043
(SecA_PP_bind)
PF07516
(SecA_SW)
PF07517
(SecA_DEAD)
4 THR A 110
LEU A 115
GLY A  88
LEU A  85
None
1.05A 1gtiD-2ipcA:
undetectable
1gtiD-2ipcA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nz9 BOTULINUM NEUROTOXIN
TYPE A


(Clostridium
botulinum)
PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N)
4 THR A 109
LEU A 107
GLY A 104
TYR A 349
None
1.00A 1gtiD-2nz9A:
undetectable
1gtiD-2nz9A:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wsc PHOTOSYSTEM I
REACTION CENTER
SUBUNIT VI,
CHLOROPLASTIC


(Spinacia
oleracea)
PF03244
(PSI_PsaH)
4 THR H  66
LEU H  64
GLY H  61
LEU H  59
None
CLA  H1079 ( 3.9A)
None
None
1.05A 1gtiD-2wscH:
undetectable
1gtiD-2wscH:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wu8 GLUCOSE-6-PHOSPHATE
ISOMERASE


(Mycobacterium
tuberculosis)
PF00342
(PGI)
4 THR A 203
LEU A 205
GLY A 143
LEU A 233
None
0.90A 1gtiD-2wu8A:
undetectable
1gtiD-2wu8A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ww9 SEC SIXTY-ONE
PROTEIN HOMOLOG


(Saccharomyces
cerevisiae)
PF00344
(SecY)
PF10559
(Plug_translocon)
4 THR A 164
GLY A 159
LEU A 157
TYR A 128
None
1.04A 1gtiD-2ww9A:
undetectable
1gtiD-2ww9A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xi7 RNA POLYMERASE L

(California
encephalitis
orthobunyavirus)
PF15518
(L_protein_N)
4 THR A  77
LEU A 112
LYS A 108
TYR A 109
None
1.06A 1gtiD-2xi7A:
undetectable
1gtiD-2xi7A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yok EXOGLUCANASE 1

(Trichoderma
harzianum)
PF00840
(Glyco_hydro_7)
5 THR A  22
LEU A  89
GLY A  91
LYS A 179
TYR A 180
None
PCA  A  18 ( 4.5A)
None
None
None
1.44A 1gtiD-2yokA:
undetectable
1gtiD-2yokA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yqu 2-OXOGLUTARATE
DEHYDROGENASE E3
COMPONENT


(Thermus
thermophilus)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
4 THR A 227
LEU A 196
GLY A 174
LEU A 180
None
1.01A 1gtiD-2yquA:
undetectable
1gtiD-2yquA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a74 LYSYL-TRNA
SYNTHETASE


(Geobacillus
stearothermophilus)
PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
4 LEU A 188
GLY A 192
LEU A 194
TYR A 246
None
0.90A 1gtiD-3a74A:
undetectable
1gtiD-3a74A:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cux MALATE SYNTHASE

(Bacillus
anthracis)
PF01274
(Malate_synthase)
4 TRP A 363
GLY A 272
LEU A 245
LYS A 212
None
None
MG  A   1 ( 4.9A)
MG  A   1 ( 4.2A)
0.85A 1gtiD-3cuxA:
undetectable
1gtiD-3cuxA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d46 PUTATIVE GALACTONATE
DEHYDRATASE


(Salmonella
enterica)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 LEU A 384
LEU A 154
LYS A 158
TYR A 157
None
1.06A 1gtiD-3d46A:
undetectable
1gtiD-3d46A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gnn NICOTINATE-NUCLEOTID
E PYROPHOSPHORYLASE


(Burkholderia
pseudomallei)
PF01729
(QRPTase_C)
PF02749
(QRPTase_N)
4 LEU A 152
GLY A 154
LEU A 157
LYS A 160
None
0.94A 1gtiD-3gnnA:
undetectable
1gtiD-3gnnA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i04 CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT BETA


(Moorella
thermoacetica)
PF03063
(Prismane)
4 THR A 318
LEU A 323
GLY A 314
LEU A 312
None
1.02A 1gtiD-3i04A:
undetectable
1gtiD-3i04A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m4a PUTATIVE TYPE I
TOPOISOMERASE


(Deinococcus
radiodurans)
PF01028
(Topoisom_I)
4 THR A 322
LEU A 318
GLY A 320
LEU A 102
None
1.01A 1gtiD-3m4aA:
undetectable
1gtiD-3m4aA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n2t PUTATIVE
OXIDOREDUCTASE


(Gluconobacter
oxydans)
PF00248
(Aldo_ket_red)
4 TRP A  23
LEU A 183
GLY A 209
LEU A 281
None
0.70A 1gtiD-3n2tA:
undetectable
1gtiD-3n2tA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nrn UNCHARACTERIZED
PROTEIN PF1083


(Pyrococcus
furiosus)
PF01593
(Amino_oxidase)
4 THR A 208
LEU A  29
GLY A   7
LEU A  13
None
None
AMP  A 422 (-3.2A)
None
1.04A 1gtiD-3nrnA:
undetectable
1gtiD-3nrnA:
21.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3o76 GLUTATHIONE
S-TRANSFERASE P 1


(Mus musculus)
PF02798
(GST_N)
PF14497
(GST_C_3)
7 TRP A  38
THR A  46
LEU A  48
GLY A  50
LEU A  52
LYS A  54
TYR A  63
GTB  A 210 (-4.0A)
None
None
None
GTB  A 210 (-4.9A)
None
None
0.42A 1gtiD-3o76A:
34.9
1gtiD-3o76A:
99.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3omv RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE


(Homo sapiens)
PF07714
(Pkinase_Tyr)
4 TRP A 423
THR A 353
LEU A 351
GLY A 366
SM5  A   1 (-4.3A)
None
None
None
0.99A 1gtiD-3omvA:
undetectable
1gtiD-3omvA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p54 ENVELOPE
GLYCOPROTEIN


(Japanese
encephalitis
virus)
PF00869
(Flavi_glycoprot)
PF02832
(Flavi_glycop_C)
4 LEU A 285
GLY A 283
LEU A 280
TYR A 137
None
0.94A 1gtiD-3p54A:
undetectable
1gtiD-3p54A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qtg PYRUVATE KINASE

(Pyrobaculum
aerophilum)
PF00224
(PK)
PF02887
(PK_C)
4 THR A 276
LEU A 278
GLY A 281
LEU A 354
None
1.00A 1gtiD-3qtgA:
undetectable
1gtiD-3qtgA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rr6 PUTATIVE
UNCHARACTERIZED
PROTEIN


(Mycobacteroides
abscessus)
PF01557
(FAA_hydrolase)
PF10370
(DUF2437)
4 LEU A 178
GLY A 139
LEU A   3
LYS A   1
None
0.96A 1gtiD-3rr6A:
undetectable
1gtiD-3rr6A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3stj PROTEASE DEGQ

(Escherichia
coli)
PF13180
(PDZ_2)
PF13365
(Trypsin_2)
4 THR A 203
LEU A 191
GLY A 189
LEU A  78
None
0.96A 1gtiD-3stjA:
undetectable
1gtiD-3stjA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3td7 FAD-LINKED
SULFHYDRYL OXIDASE
R596


(Acanthamoeba
polyphaga
mimivirus)
PF04777
(Evr1_Alr)
4 THR A 207
LEU A 209
GLY A 211
LEU A 265
None
1.07A 1gtiD-3td7A:
undetectable
1gtiD-3td7A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vml 3-ISOPROPYLMALATE
DEHYDROGENASE


(Shewanella
benthica;
Shewanella
oneidensis)
PF00180
(Iso_dh)
4 LEU A 246
GLY A 248
LEU A 138
TYR A 143
CL  A 403 (-4.6A)
None
None
IPM  A 401 (-4.5A)
1.03A 1gtiD-3vmlA:
undetectable
1gtiD-3vmlA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vr1 PEPTIDE CHAIN
RELEASE FACTOR 3


(Desulfovibrio
vulgaris)
PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF16658
(RF3_C)
4 THR A 134
LEU A 245
GLY A 247
TYR A 244
None
0.98A 1gtiD-3vr1A:
undetectable
1gtiD-3vr1A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wsy SORTILIN-RELATED
RECEPTOR


(Homo sapiens)
PF15901
(Sortilin_C)
PF15902
(Sortilin-Vps10)
4 LEU A 745
GLY A 747
LYS A 730
TYR A 682
None
0.98A 1gtiD-3wsyA:
undetectable
1gtiD-3wsyA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zok 3-DEHYDROQUINATE
SYNTHASE


(Actinidia
chinensis)
PF01761
(DHQ_synthase)
4 THR A 144
LEU A 192
GLY A 195
LEU A 277
NAD  A1381 (-3.5A)
None
None
None
0.98A 1gtiD-3zokA:
undetectable
1gtiD-3zokA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4av6 K(+)-STIMULATED
PYROPHOSPHATE-ENERGI
ZED SODIUM PUMP


(Thermotoga
maritima)
PF03030
(H_PPase)
4 TRP A 659
THR A 652
GLY A 413
LEU A 410
None
0.96A 1gtiD-4av6A:
1.2
1gtiD-4av6A:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c6o CAD PROTEIN

(Homo sapiens)
PF01979
(Amidohydro_1)
4 TRP A1581
THR A1547
GLY A1550
LEU A1535
None
0.89A 1gtiD-4c6oA:
undetectable
1gtiD-4c6oA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4chl PERSULFIDE
DIOXYGENASE ETHE1,
MITOCHONDRIAL


(Homo sapiens)
PF00753
(Lactamase_B)
4 THR A  57
LEU A  90
GLY A  87
LEU A  50
None
1.04A 1gtiD-4chlA:
undetectable
1gtiD-4chlA:
26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cns DIHYDROPYRIMIDINASE-
LIKE 3


(Homo sapiens)
PF01979
(Amidohydro_1)
4 THR A 384
LEU A 328
GLY A 330
LEU A 283
None
0.97A 1gtiD-4cnsA:
undetectable
1gtiD-4cnsA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cnt DIHYDROPYRIMIDINASE-
LIKE 3


(Homo sapiens)
PF01979
(Amidohydro_1)
4 THR A 384
LEU A 328
GLY A 330
LEU A 283
None
0.94A 1gtiD-4cntA:
undetectable
1gtiD-4cntA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cuo BANYAN PEROXIDASE

(Ficus
benghalensis)
PF00141
(peroxidase)
4 THR A 245
GLY A 241
LEU A 220
TYR A 232
HEM  A1307 (-3.5A)
None
None
None
0.82A 1gtiD-4cuoA:
undetectable
1gtiD-4cuoA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cza NA+/H+ ANTIPORTER,
PUTATIVE


(Pyrococcus
abyssi)
PF00999
(Na_H_Exchanger)
4 GLY A 266
LEU A 270
LYS A 269
TYR A 268
None
1.07A 1gtiD-4czaA:
undetectable
1gtiD-4czaA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dje CORRINOID/IRON-SULFU
R PROTEIN SMALL
SUBUNIT


(Moorella
thermoacetica)
PF03599
(CdhD)
4 LEU D 300
GLY D 254
LYS D 101
TYR D  99
None
0.97A 1gtiD-4djeD:
undetectable
1gtiD-4djeD:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dpg LYSINE--TRNA LIGASE

(Homo sapiens)
PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
4 LEU A 258
GLY A 262
LEU A 264
TYR A 316
None
0.95A 1gtiD-4dpgA:
undetectable
1gtiD-4dpgA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f92 U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE


(Homo sapiens)
PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63)
4 TRP B1652
THR B1352
LEU B1490
LEU B1458
None
0.99A 1gtiD-4f92B:
undetectable
1gtiD-4f92B:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fsp PROBABLE PORIN

(Pseudomonas
aeruginosa)
PF03573
(OprD)
4 THR A 135
LEU A 146
GLY A 185
LEU A 114
None
None
C8E  A 406 ( 4.0A)
None
0.94A 1gtiD-4fspA:
undetectable
1gtiD-4fspA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gqy CBS
DOMAIN-CONTAINING
PROTEIN CBSX2,
CHLOROPLASTIC


(Arabidopsis
thaliana)
PF00571
(CBS)
4 THR A 178
LEU A 176
GLY A 174
LYS A 163
AMP  A 301 (-3.4A)
None
None
None
1.06A 1gtiD-4gqyA:
undetectable
1gtiD-4gqyA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j2u ENOYL-COA HYDRATASE

(Rhodobacter
sphaeroides)
PF16113
(ECH_2)
4 THR A 110
LEU A  23
GLY A  63
LEU A  26
None
0.88A 1gtiD-4j2uA:
undetectable
1gtiD-4j2uA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kk2 MONOTERPENE SYNTHASE
FDS-5, CHLOROPLASTIC
- FARNESYL
DIPHOSPHATE SYNTHASE
1 CHIMERA


(Artemisia
spiciformis)
PF00348
(polyprenyl_synt)
4 LEU A 209
GLY A 212
LYS A 144
TYR A 146
None
1.01A 1gtiD-4kk2A:
undetectable
1gtiD-4kk2A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4psp ALPHA-FUCOSIDASE
GH29


(Fusarium
graminearum)
PF01120
(Alpha_L_fucos)
PF16757
(Fucosidase_C)
4 GLY A 370
LEU A 451
LYS A 488
TYR A 417
None
0.94A 1gtiD-4pspA:
undetectable
1gtiD-4pspA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qts CRISPR TYPE
III-ASSOCIATED RAMP
PROTEIN CSM4


(Methanocaldococcus
jannaschii)
PF03787
(RAMPs)
4 LEU A  50
GLY A  46
LYS A 220
TYR A  41
None
1.06A 1gtiD-4qtsA:
undetectable
1gtiD-4qtsA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qvg SIBL

(Streptosporangium
sibiricum)
PF00891
(Methyltransf_2)
PF16864
(Dimerisation2)
4 THR A  63
LEU A  67
GLY A  78
LEU A  33
None
0.90A 1gtiD-4qvgA:
undetectable
1gtiD-4qvgA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rew 5'-AMP-ACTIVATED
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA-1


(Homo sapiens)
PF00069
(Pkinase)
PF16579
(AdenylateSensor)
4 THR A 174
GLY A 189
LEU A 191
TYR A 192
None
1.04A 1gtiD-4rewA:
undetectable
1gtiD-4rewA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tx2 NON-RIBOSOMAL
PEPTIDE SYNTHETASE


(Actinoplanes
teichomyceticus)
PF00668
(Condensation)
4 THR B 285
LEU B 363
GLY B 283
LEU B 395
None
0.96A 1gtiD-4tx2B:
undetectable
1gtiD-4tx2B:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4up7 LYSINE--TRNA LIGASE

(Entamoeba
histolytica)
PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
4 LEU A 186
GLY A 190
LEU A 192
TYR A 244
None
0.99A 1gtiD-4up7A:
undetectable
1gtiD-4up7A:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE


(Bacillus
licheniformis)
PF09924
(DUF2156)
4 THR A 842
LEU A 844
GLY A 846
LEU A 698
None
None
None
LYN  A1851 ( 4.3A)
1.04A 1gtiD-4v36A:
undetectable
1gtiD-4v36A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v3i VCA0115

(Vibrio cholerae)
PF09850
(DotU)
4 THR A  44
LEU A  46
GLY A  48
LEU A 162
None
1.00A 1gtiD-4v3iA:
undetectable
1gtiD-4v3iA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wbo RHODOPSIN KINASE

(Bos taurus)
PF00069
(Pkinase)
PF00615
(RGS)
4 TRP A 174
THR A 522
GLY A 526
LEU A 528
None
1.02A 1gtiD-4wboA:
undetectable
1gtiD-4wboA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE


(Pseudomonas
aeruginosa)
PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
PF02938
(GAD)
4 LEU M 155
GLY M 159
LEU M 161
TYR M 213
None
1.06A 1gtiD-4wj3M:
undetectable
1gtiD-4wj3M:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xk8 PUTATIVE
UNCHARACTERIZED
PROTEIN


(Pisum sativum)
PF02605
(PsaL)
4 THR L 136
LEU L  46
GLY L  49
LEU L 126
None
1.03A 1gtiD-4xk8L:
undetectable
1gtiD-4xk8L:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y4n PUTATIVE RIBOSE
1,5-BISPHOSPHATE
ISOMERASE


(Methanotorris
igneus)
PF01946
(Thi4)
4 THR A 129
LEU A  58
GLY A  36
LEU A  42
None
None
48H  A 302 (-3.2A)
None
0.98A 1gtiD-4y4nA:
undetectable
1gtiD-4y4nA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bza BETA-N-ACETYLHEXOSAM
INIDASE


(Thermotoga
neapolitana)
PF00933
(Glyco_hydro_3)
4 THR A 204
LEU A 241
GLY A 240
LEU A 232
None
0.91A 1gtiD-5bzaA:
undetectable
1gtiD-5bzaA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d1r RV1816
TRANSCRIPTIONAL
REGULATOR


(Mycobacterium
tuberculosis)
PF00440
(TetR_N)
4 TRP A  91
THR A 224
LEU A 226
LEU A 231
None
1.01A 1gtiD-5d1rA:
undetectable
1gtiD-5d1rA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dcq FIBRONECTIN-BINDING
PROTEIN


(Streptococcus
equi)
PF08341
(TED)
4 LEU D  66
LEU D   2
LYS D  23
TYR D   4
None
1.04A 1gtiD-5dcqD:
undetectable
1gtiD-5dcqD:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e9h ISOCITRATE LYASE

(Fusarium
graminearum)
PF00463
(ICL)
4 THR A 186
LEU A 191
GLY A 183
TYR A 129
None
1.05A 1gtiD-5e9hA:
undetectable
1gtiD-5e9hA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ejy MYOSIN-I HEAVY CHAIN

(Dictyostelium
discoideum)
PF00784
(MyTH4)
4 LEU A 468
GLY A 472
LEU A 535
TYR A 531
None
1.06A 1gtiD-5ejyA:
undetectable
1gtiD-5ejyA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eks 3-DEHYDROQUINATE
SYNTHASE


(Acinetobacter
baumannii)
PF01761
(DHQ_synthase)
4 THR A 129
LEU A 177
GLY A 180
LEU A 262
NAD  A 400 (-2.7A)
None
None
None
0.99A 1gtiD-5eksA:
undetectable
1gtiD-5eksA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eo7 PREDICTED PROTEIN

(Aspergillus
oryzae)
PF07938
(Fungal_lectin)
4 TRP A 271
THR A 293
LEU A 278
LEU A  24
None
SFU  A 405 ( 4.1A)
None
SFU  A 405 ( 4.1A)
1.07A 1gtiD-5eo7A:
undetectable
1gtiD-5eo7A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f7u CYCLOALTERNAN-FORMIN
G ENZYME


(Listeria
monocytogenes)
PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF16338
(DUF4968)
PF16990
(CBM_35)
4 THR A 128
GLY A 126
LYS A  33
TYR A 134
None
1.04A 1gtiD-5f7uA:
undetectable
1gtiD-5f7uA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fzp DISPASE
AUTOLYSIS-INDUCING
PROTEIN


(Streptomyces
mobaraensis)
no annotation 4 TRP A 201
THR A 171
GLY A 143
LEU A 145
None
1.01A 1gtiD-5fzpA:
undetectable
1gtiD-5fzpA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gv1 ENDO-1,4-BETA-XYLANA
SE


(termite gut
metagenome)
PF00457
(Glyco_hydro_11)
4 LEU A  23
GLY A  25
LYS A  73
TYR A  62
None
1.05A 1gtiD-5gv1A:
undetectable
1gtiD-5gv1A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hgq LYSINE--TRNA LIGASE

(Loa loa)
PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
4 LEU A 190
GLY A 194
LEU A 196
TYR A 248
None
1.02A 1gtiD-5hgqA:
undetectable
1gtiD-5hgqA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i67 PHOSPHOENOLPYRUVATE
CARBOXYKINASE [GTP]


(Mycobacterium
tuberculosis)
PF00821
(PEPCK_C)
PF17297
(PEPCK_N)
4 GLY A 408
LEU A 293
LYS A 254
TYR A 264
PEG  A 702 ( 4.8A)
None
None
None
0.94A 1gtiD-5i67A:
undetectable
1gtiD-5i67A:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iso 5'-AMP-ACTIVATED
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA-2


(Homo sapiens)
PF00069
(Pkinase)
PF16579
(AdenylateSensor)
4 THR A 172
GLY A 187
LEU A 189
TYR A 190
None
0.98A 1gtiD-5isoA:
undetectable
1gtiD-5isoA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j1i PLECTIN

(Homo sapiens)
no annotation 4 TRP A1249
THR A1354
LEU A1356
LEU A1250
None
1.05A 1gtiD-5j1iA:
undetectable
1gtiD-5j1iA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jd8 PERIPLASMIC SERINE
PEPTIDASE DEGS


(Yersinia pestis)
PF13180
(PDZ_2)
PF13365
(Trypsin_2)
4 THR A 216
LEU A 204
GLY A 202
LEU A  92
None
1.04A 1gtiD-5jd8A:
undetectable
1gtiD-5jd8A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lki TCDA1

(Photorhabdus
luminescens)
PF03538
(VRP1)
4 LEU A2375
GLY A2369
LEU A2344
TYR A2341
None
0.90A 1gtiD-5lkiA:
undetectable
1gtiD-5lkiA:
6.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B


(Acinetobacter
calcoaceticus)
no annotation 4 THR A 194
LEU A 225
GLY A 197
LEU A 200
None
1.05A 1gtiD-5minA:
undetectable
1gtiD-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u84 ACID CERAMIDASE

(Balaenoptera
acutorostrata)
no annotation 4 TRP A  62
LEU A 211
GLY A 209
LEU A 189
None
1.07A 1gtiD-5u84A:
undetectable
1gtiD-5u84A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN


(Thermothelomyces
thermophila)
PF03443
(Glyco_hydro_61)
4 THR A  74
LEU A 131
GLY A 134
LYS A   2
HIC  A   1 (-3.7A)
None
None
HIC  A   1 ( 3.6A)
0.89A 1gtiD-5ufvA:
undetectable
1gtiD-5ufvA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 5


(Homo sapiens)
PF13191
(AAA_16)
PF14630
(ORC5_C)
4 THR E  39
GLY E  37
LEU E 157
LYS E 126
ATP  E 301 (-3.9A)
None
None
ATP  E 301 ( 3.7A)
0.87A 1gtiD-5uj7E:
undetectable
1gtiD-5uj7E:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ujm ORIGIN RECOGNITION
COMPLEX SUBUNIT 5


(Homo sapiens)
PF13191
(AAA_16)
PF14630
(ORC5_C)
4 THR E  39
GLY E  37
LEU E 157
LYS E 126
ATP  E 501 (-3.9A)
None
None
ATP  E 501 ( 3.7A)
0.87A 1gtiD-5ujmE:
undetectable
1gtiD-5ujmE:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vbb RNA PSEUDOURIDYLATE
SYNTHASE
DOMAIN-CONTAINING
PROTEIN 1


(Homo sapiens)
PF00849
(PseudoU_synth_2)
4 GLY A  72
LEU A 213
LYS A  97
TYR A  99
None
None
GOL  A 306 (-3.1A)
GOL  A 306 (-3.8A)
0.88A 1gtiD-5vbbA:
undetectable
1gtiD-5vbbA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w21 KLOTHO

(Homo sapiens)
no annotation 4 THR A 810
LEU A 852
GLY A 851
TYR A 894
None
1.06A 1gtiD-5w21A:
undetectable
1gtiD-5w21A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xg2 CHROMOSOME PARTITION
PROTEIN SMC


(Pyrococcus
yayanosii)
PF05483
(SCP-1)
4 THR A 393
LEU A 398
LEU A 771
LYS A 767
None
0.90A 1gtiD-5xg2A:
undetectable
1gtiD-5xg2A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xqo PCRGLX PROTEIN

(Penicillium
chrysogenum)
no annotation 4 TRP A  89
LEU A 504
GLY A  47
LEU A 661
None
0.78A 1gtiD-5xqoA:
1.4
1gtiD-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6chd LYSINE--TRNA LIGASE

(Homo sapiens)
no annotation 4 LEU A 258
GLY A 262
LEU A 264
TYR A 316
None
0.92A 1gtiD-6chdA:
undetectable
1gtiD-6chdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d9z SULFATE TRANSPORTER
CYSZ


(Pseudomonas
denitrificans
(nomen
rejiciendum))
no annotation 4 LEU F  10
GLY F 230
LEU F  16
LYS F  15
None
0.89A 1gtiD-6d9zF:
undetectable
1gtiD-6d9zF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fml INO80

(Chaetomium
thermophilum)
no annotation 4 TRP G 982
LEU G1133
GLY G 993
LEU G 983
None
0.97A 1gtiD-6fmlG:
undetectable
1gtiD-6fmlG:
undetectable