SIMILAR PATTERNS OF AMINO ACIDS FOR 1GTB_A_PZQA901_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g5b SERINE/THREONINE
PROTEIN PHOSPHATASE

(Escherichia
virus Lambda) 		PF00149
(Metallophos) 		3 GLN A  78
TYR A   3
ARG A   2
 None
 0.83A 1gtbA-1g5bA:
undetectable		 1gtbA-1g5bA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k1x 4-ALPHA-GLUCANOTRANS
FERASE

(Thermococcus
litoralis) 		PF03065
(Glyco_hydro_57)
PF09094
(DUF1925)
PF09095
(DUF1926) 		3 GLN A 489
TYR A 502
ARG A 503
 None
 0.87A 1gtbA-1k1xA:
0.0		 1gtbA-1k1xA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l1l RIBONUCLEOSIDE
TRIPHOSPHATE
REDUCTASE

(Lactobacillus
leichmannii) 		PF02867
(Ribonuc_red_lgC) 		3 GLN A 109
TYR A 446
ARG A 445
 None
 0.81A 1gtbA-1l1lA:
0.0		 1gtbA-1l1lA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l5a AMIDE SYNTHASE

(Vibrio cholerae) 		PF00668
(Condensation) 		3 GLN A 318
TYR A 311
ARG A 310
 None
 0.91A 1gtbA-1l5aA:
0.1		 1gtbA-1l5aA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1om9 ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1

(Homo sapiens) 		PF02883
(Alpha_adaptinC2) 		3 GLN A 520
TYR A 610
ARG A 609
 None
 0.79A 1gtbA-1om9A:
undetectable		 1gtbA-1om9A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1phz PROTEIN
(PHENYLALANINE
HYDROXYLASE)

(Rattus
norvegicus) 		PF00351
(Biopterin_H)
PF01842
(ACT) 		3 GLN A 126
TYR A 414
ARG A 413
 None
 0.91A 1gtbA-1phzA:
undetectable		 1gtbA-1phzA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s9c PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2

(Homo sapiens) 		PF01575
(MaoC_dehydratas)
PF13452
(MaoC_dehydrat_N) 		3 GLN A  92
TYR A 188
ARG A 189
 None
 0.95A 1gtbA-1s9cA:
undetectable		 1gtbA-1s9cA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica) 		PF13531
(SBP_bac_11) 		3 GLN A 152
TYR A 137
ARG A 134
 None
 0.95A 1gtbA-1sbpA:
undetectable		 1gtbA-1sbpA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t0a 2C-METHYL-D-ERYTHRIT
OL
2,4-CYCLODIPHOSPHATE
SYNTHASE

(Shewanella
oneidensis) 		PF02542
(YgbB) 		3 GLN A 159
TYR A  83
ARG A  80
 None
 0.87A 1gtbA-1t0aA:
0.0		 1gtbA-1t0aA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tme THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP2)

(Cardiovirus B) 		PF00073
(Rhv) 		3 GLN 2 183
TYR 2 167
ARG 2 168
 None
 0.95A 1gtbA-1tme2:
undetectable		 1gtbA-1tme2:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wue MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY PROTEIN

(Enterococcus
faecalis) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 GLN A1149
TYR A1169
ARG A1166
 None
 0.73A 1gtbA-1wueA:
undetectable		 1gtbA-1wueA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xvx YFUA

(Yersinia
enterocolitica) 		PF13343
(SBP_bac_6) 		3 GLN A  13
TYR A 199
ARG A 200
 None
FE  A 313 (-4.3A)
None
 0.93A 1gtbA-1xvxA:
undetectable		 1gtbA-1xvxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b39 C3

(Bos taurus) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		3 GLN A 482
TYR A 488
ARG A 503
 None
 0.95A 1gtbA-2b39A:
3.0		 1gtbA-2b39A:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c81 GLUTAMINE-2-DEOXY-SC
YLLO-INOSOSE
AMINOTRANSFERASE

(Bacillus
circulans) 		PF01041
(DegT_DnrJ_EryC1) 		3 GLN A 190
TYR A 337
ARG A 328
 None
 0.86A 1gtbA-2c81A:
undetectable		 1gtbA-2c81A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cjq RNA-DIRECTED RNA
POLYMERASE

(Pestivirus A) 		PF00998
(RdRP_3) 		3 GLN A 308
TYR A 369
ARG A 370
 None
 0.94A 1gtbA-2cjqA:
undetectable		 1gtbA-2cjqA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e0t DUAL SPECIFICITY
PHOSPHATASE 26

(Homo sapiens) 		PF00782
(DSPc) 		3 GLN A  74
TYR A 106
ARG A 112
 None
 0.93A 1gtbA-2e0tA:
undetectable		 1gtbA-2e0tA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ea1 RIBONUCLEASE I

(Escherichia
coli) 		PF00445
(Ribonuclease_T2) 		3 GLN A   4
TYR A  14
ARG A  13
 None
 0.63A 1gtbA-2ea1A:
undetectable		 1gtbA-2ea1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2epk N-ACETYL-BETA-D-GLUC
OSAMINIDASE

(Streptococcus
gordonii) 		PF00728
(Glyco_hydro_20) 		3 GLN X 383
TYR X 142
ARG X 141
 None
 0.69A 1gtbA-2epkX:
undetectable		 1gtbA-2epkX:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hd7 TWINFILIN-1

(Mus musculus) 		PF00241
(Cofilin_ADF) 		3 GLN A 202
TYR A 272
ARG A 269
 None
 0.95A 1gtbA-2hd7A:
undetectable		 1gtbA-2hd7A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i6x HYDROLASE, HALOACID
DEHALOGENASE-LIKE
FAMILY

(Porphyromonas
gingivalis) 		PF13419
(HAD_2) 		3 GLN A 207
TYR A 102
ARG A 103
 None
 0.84A 1gtbA-2i6xA:
undetectable		 1gtbA-2i6xA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iw1 LIPOPOLYSACCHARIDE
CORE BIOSYNTHESIS
PROTEIN RFAG

(Escherichia
coli) 		PF00534
(Glycos_transf_1)
PF13439
(Glyco_transf_4) 		3 GLN A 324
TYR A 279
ARG A 208
 None
None
U2F  A 900 (-3.0A)
 0.82A 1gtbA-2iw1A:
undetectable		 1gtbA-2iw1A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j7a CYTOCHROME C NITRITE
REDUCTASE NRFA

(Desulfovibrio
vulgaris) 		PF02335
(Cytochrom_C552) 		3 GLN A 380
TYR A 115
ARG A 116
 None
HEM  A1001 (-4.7A)
None
 0.92A 1gtbA-2j7aA:
undetectable		 1gtbA-2j7aA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jnu REGULATOR OF
G-PROTEIN SIGNALING
14

(Homo sapiens) 		PF00615
(RGS) 		3 GLN A   6
TYR A 127
ARG A 128
 None
 0.84A 1gtbA-2jnuA:
undetectable		 1gtbA-2jnuA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jsp TRANSCRIPTIONAL
REGULATORY PROTEIN
ROS

(Agrobacterium
tumefaciens) 		PF05443
(ROS_MUCR) 		3 GLN A   7
TYR A  49
ARG A  50
 None
 0.89A 1gtbA-2jspA:
undetectable		 1gtbA-2jspA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k2q SURFACTIN SYNTHETASE
THIOESTERASE SUBUNIT

(Bacillus
subtilis) 		PF00975
(Thioesterase) 		3 GLN B 115
TYR B 164
ARG B 165
 None
 0.92A 1gtbA-2k2qB:
undetectable		 1gtbA-2k2qB:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l8a ENDOGLUCANASE

(Bacillus
subtilis) 		PF00942
(CBM_3) 		3 GLN A 466
TYR A 358
ARG A 359
 None
 0.96A 1gtbA-2l8aA:
undetectable		 1gtbA-2l8aA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m3c CRYSTALLIN, GAMMA M7

(Danio rerio) 		PF00030
(Crystall) 		3 GLN A  55
TYR A 152
ARG A 153
 None
 0.95A 1gtbA-2m3cA:
undetectable		 1gtbA-2m3cA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o5p FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa) 		PF00593
(TonB_dep_Rec)
PF07660
(STN)
PF07715
(Plug) 		3 GLN A 136
TYR A  72
ARG A  73
 None
 0.92A 1gtbA-2o5pA:
undetectable		 1gtbA-2o5pA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xa7 ADAPTOR-RELATED
PROTEIN COMPLEX 2,
ALPHA 2 SUBUNIT
AP-2 COMPLEX SUBUNIT
BETA

(Rattus
norvegicus;
Homo sapiens) 		PF01602
(Adaptin_N)
PF01602
(Adaptin_N) 		3 GLN B 481
TYR A 463
ARG A 464
 None
 0.62A 1gtbA-2xa7B:
2.6		 1gtbA-2xa7B:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xyd ANGIOTENSIN-CONVERTI
NG ENZYME

(Homo sapiens) 		PF01401
(Peptidase_M2) 		3 GLN A   9
TYR A  76
ARG A  96
 None
None
PEG  A1624 (-4.1A)
 0.87A 1gtbA-2xydA:
undetectable		 1gtbA-2xydA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ycb CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR

(Methanothermobacter
thermautotrophicus) 		PF07521
(RMMBL)
PF10996
(Beta-Casp)
PF16661
(Lactamase_B_6)
PF17214
(KH_7) 		3 GLN A 546
TYR A 380
ARG A 582
 None
 0.95A 1gtbA-2ycbA:
undetectable		 1gtbA-2ycbA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yd0 ENDOPLASMIC
RETICULUM
AMINOPEPTIDASE 1

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		3 GLN A 358
TYR A 327
ARG A 328
 None
 0.90A 1gtbA-2yd0A:
undetectable		 1gtbA-2yd0A:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aq2 6B PROTEIN

(Agrobacterium
vitis) 		PF02027
(RolB_RolC) 		3 GLN A 138
TYR A 192
ARG A  79
 None
 0.74A 1gtbA-3aq2A:
undetectable		 1gtbA-3aq2A:
17.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3cru GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME

(Schistosoma
japonicum) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		3 GLN A  67
TYR A 104
ARG A 108
 GSH  A 215 (-3.2A)
None
None
 0.76A 1gtbA-3cruA:
36.2		 1gtbA-3cruA:
99.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fkj PUTATIVE
PHOSPHOSUGAR
ISOMERASES

(Salmonella
enterica) 		PF01380
(SIS) 		3 GLN A 183
TYR A 126
ARG A 125
 None
 0.75A 1gtbA-3fkjA:
2.2		 1gtbA-3fkjA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gyd CYCLIC
NUCLEOTIDE-BINDING
DOMAIN

(Methylobacillus
flagellatus) 		PF00027
(cNMP_binding) 		3 GLN A 128
TYR A  38
ARG A  37
 None
 0.85A 1gtbA-3gydA:
undetectable		 1gtbA-3gydA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i5g MYOSIN HEAVY CHAIN
ISOFORM A

(Doryteuthis
pealeii) 		PF00063
(Myosin_head)
PF00612
(IQ)
PF02736
(Myosin_N) 		3 GLN A 692
TYR A 126
ARG A 127
 None
 0.95A 1gtbA-3i5gA:
undetectable		 1gtbA-3i5gA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ic7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Bacteroides
thetaiotaomicron) 		PF00392
(GntR) 		3 GLN A  87
TYR A  55
ARG A  51
 None
 0.85A 1gtbA-3ic7A:
undetectable		 1gtbA-3ic7A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kvn ESTERASE ESTA

(Pseudomonas
aeruginosa) 		no annotation 3 GLN X 176
TYR X  99
ARG X 166
 None
 0.94A 1gtbA-3kvnX:
undetectable		 1gtbA-3kvnX:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l5h INTERLEUKIN-6
RECEPTOR SUBUNIT
BETA

(Homo sapiens) 		PF00041
(fn3)
PF06328
(Lep_receptor_Ig)
PF09240
(IL6Ra-bind) 		3 GLN A 356
TYR A 374
ARG A 373
 None
None
SO4  A 592 (-3.0A)
 0.89A 1gtbA-3l5hA:
undetectable		 1gtbA-3l5hA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lmm UNCHARACTERIZED
PROTEIN

(Corynebacterium
diphtheriae) 		PF04326
(AlbA_2)
PF13749
(HATPase_c_4) 		3 GLN A 455
TYR A 430
ARG A 378
 None
 0.89A 1gtbA-3lmmA:
undetectable		 1gtbA-3lmmA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3moz MYO-INOSITOL
HEXAPHOSPHATE
PHOSPHOHYDROLASE

(Selenomonas
ruminantium) 		PF14566
(PTPlike_phytase) 		3 GLN A 161
TYR A 216
ARG A 215
 None
 0.96A 1gtbA-3mozA:
undetectable		 1gtbA-3mozA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3od1 ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT

(Bacillus
halodurans) 		PF13393
(tRNA-synt_His) 		3 GLN A  63
TYR A 190
ARG A 186
 None
 0.69A 1gtbA-3od1A:
undetectable		 1gtbA-3od1A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oxp PHOSPHOTRANSFERASE
ENZYME II, A
COMPONENT

(Yersinia pestis) 		PF00359
(PTS_EIIA_2) 		3 GLN A  29
TYR A  46
ARG A  47
 None
 0.79A 1gtbA-3oxpA:
undetectable		 1gtbA-3oxpA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN

(Escherichia
coli;
Escherichia
coli) 		PF01409
(tRNA-synt_2d)
PF02912
(Phe_tRNA-synt_N)
PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		3 GLN B 588
TYR A 194
ARG A 195
 None
None
AMP  A 992 (-4.0A)
 0.95A 1gtbA-3pcoB:
undetectable		 1gtbA-3pcoB:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sks PUTATIVE
OLIGOENDOPEPTIDASE F

(Bacillus
anthracis) 		no annotation 3 GLN A  85
TYR A 224
ARG A 225
 None
 0.94A 1gtbA-3sksA:
undetectable		 1gtbA-3sksA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tt2 GCN5-RELATED
N-ACETYLTRANSFERASE

(Sphaerobacter
thermophilus) 		PF00583
(Acetyltransf_1) 		3 GLN A 103
TYR A 144
ARG A 145
 None
 0.84A 1gtbA-3tt2A:
undetectable		 1gtbA-3tt2A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u4c BACILYSIN
BIOSYNTHESIS
OXIDOREDUCTASE YWFH

(Bacillus
subtilis) 		PF13561
(adh_short_C2) 		3 GLN A 208
TYR A 192
ARG A 191
 None
None
NDP  A 262 (-3.9A)
 0.96A 1gtbA-3u4cA:
undetectable		 1gtbA-3u4cA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uc3 SERINE/THREONINE-PRO
TEIN KINASE SRK2I

(Arabidopsis
thaliana) 		PF00069
(Pkinase) 		3 GLN A 304
TYR A  22
ARG A  37
 None
 0.96A 1gtbA-3uc3A:
undetectable		 1gtbA-3uc3A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3udb SERINE/THREONINE-PRO
TEIN KINASE SRK2E

(Arabidopsis
thaliana) 		PF00069
(Pkinase) 		3 GLN A 303
TYR A  21
ARG A  36
 None
 0.94A 1gtbA-3udbA:
undetectable		 1gtbA-3udbA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vu2 1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME,
CHLOROPLASTIC/AMYLOP
LASTIC

(Oryza sativa) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C)
PF02922
(CBM_48) 		3 GLN A 507
TYR A 522
ARG A 182
 None
 0.82A 1gtbA-3vu2A:
undetectable		 1gtbA-3vu2A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w5n PUTATIVE
RHAMNOSIDASE

(Streptomyces
avermitilis) 		PF05592
(Bac_rhamnosid)
PF08531
(Bac_rhamnosid_N)
PF17389
(Bac_rhamnosid6H)
PF17390
(Bac_rhamnosid_C) 		3 GLN A 973
TYR A 871
ARG A 872
 None
 0.86A 1gtbA-3w5nA:
3.6		 1gtbA-3w5nA:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wec CYTOCHROME P450

(Rhodococcus
erythropolis) 		PF00067
(p450) 		3 GLN A 372
TYR A 354
ARG A 356
 None
HEM  A 501 (-4.4A)
None
 0.88A 1gtbA-3wecA:
undetectable		 1gtbA-3wecA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE

(Streptomyces
coelicolor) 		PF03664
(Glyco_hydro_62) 		3 GLN A 373
TYR A 182
ARG A 183
 None
 0.63A 1gtbA-3wmyA:
undetectable		 1gtbA-3wmyA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4byf UNCONVENTIONAL
MYOSIN-IC

(Homo sapiens) 		PF00063
(Myosin_head)
PF00612
(IQ) 		3 GLN A 610
TYR A  55
ARG A  56
 None
AOV  A1001 ( 4.5A)
None
 0.76A 1gtbA-4byfA:
undetectable		 1gtbA-4byfA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fm9 DNA TOPOISOMERASE
2-ALPHA

(Homo sapiens) 		PF00521
(DNA_topoisoIV)
PF01751
(Toprim)
PF16898
(TOPRIM_C) 		3 GLN A 933
TYR A 957
ARG A 958
 None
 0.88A 1gtbA-4fm9A:
undetectable		 1gtbA-4fm9A:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fys AMINOPEPTIDASE N

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		3 GLN A 393
TYR A 362
ARG A 363
 None
 0.81A 1gtbA-4fysA:
undetectable		 1gtbA-4fysA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i83 3-HYDROXYACYL-[ACYL-
CARRIER-PROTEIN]
DEHYDRATASE FABZ

(Neisseria
meningitidis) 		PF07977
(FabA) 		3 GLN A  49
TYR A  20
ARG A  19
 None
 0.85A 1gtbA-4i83A:
undetectable		 1gtbA-4i83A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jkg PRE-MRNA-PROCESSING-
SPLICING FACTOR 8

(Homo sapiens) 		PF12134
(PRP8_domainIV) 		3 GLN B1835
TYR B1786
ARG B1787
 None
 0.82A 1gtbA-4jkgB:
undetectable		 1gtbA-4jkgB:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4keq 4-PYRIDOXOLACTONASE

(Mesorhizobium
japonicum) 		PF00753
(Lactamase_B) 		3 GLN A 212
TYR A 260
ARG A 261
 None
 0.77A 1gtbA-4keqA:
undetectable		 1gtbA-4keqA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kxb GLUTAMYL
AMINOPEPTIDASE

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		3 GLN A 398
TYR A 367
ARG A 368
 None
 0.89A 1gtbA-4kxbA:
undetectable		 1gtbA-4kxbA:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n4r LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE

(Salmonella
enterica;
Salmonella
enterica) 		PF04453
(OstA_C)
PF04390
(LptE) 		3 GLN A 655
TYR B 123
ARG B 124
 None
 0.80A 1gtbA-4n4rA:
undetectable		 1gtbA-4n4rA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n9f CORE-BINDING FACTOR
SUBUNIT BETA
VIRION INFECTIVITY
FACTOR

(Homo sapiens;
Human
immunodeficiency
virus 1) 		no annotation
no annotation 		3 GLN a   8
TYR b  94
ARG b  93
 None
 0.93A 1gtbA-4n9fa:
undetectable		 1gtbA-4n9fa:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q4l ATP SYNTHASE SUBUNIT
BETA 1

(Burkholderia
thailandensis) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		3 GLN A 296
TYR A 262
ARG A 263
 None
 0.86A 1gtbA-4q4lA:
undetectable		 1gtbA-4q4lA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wk7 A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 4

(Homo sapiens) 		PF01421
(Reprolysin) 		3 GLN A 354
TYR A 241
ARG A 240
 None
 0.81A 1gtbA-4wk7A:
undetectable		 1gtbA-4wk7A:
19.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wr4 GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME

(Schistosoma
japonicum) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		3 GLN A  66
TYR A 103
ARG A 107
 GSH  A 301 (-3.2A)
None
None
 0.40A 1gtbA-4wr4A:
34.1		 1gtbA-4wr4A:
87.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wva UNCHARACTERIZED
PROTEIN

(Thermus
thermophilus) 		PF01204
(Trehalase) 		3 GLN A 242
TYR A 143
ARG A 140
 None
 0.94A 1gtbA-4wvaA:
3.0		 1gtbA-4wvaA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wvm STONUSTOXIN SUBUNIT
ALPHA

(Synanceia
horrida) 		PF00622
(SPRY)
PF13765
(PRY) 		3 GLN A 296
TYR A  98
ARG A 284
 None
 0.87A 1gtbA-4wvmA:
undetectable		 1gtbA-4wvmA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wz9 AGAP004809-PA

(Anopheles
gambiae) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		3 GLN A 371
TYR A 340
ARG A 341
 None
 0.82A 1gtbA-4wz9A:
undetectable		 1gtbA-4wz9A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zbl PHOTOSESITIZER
MKILLERORANGE

(Hydrozoa) 		PF01353
(GFP) 		3 GLN A 159
TYR A  74
ARG A  73
 4M9  A  65 ( 3.0A)
None
None
 0.92A 1gtbA-4zblA:
undetectable		 1gtbA-4zblA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zel DOPAMINE
BETA-HYDROXYLASE

(Homo sapiens) 		PF01082
(Cu2_monooxygen)
PF03351
(DOMON)
PF03712
(Cu2_monoox_C) 		3 GLN A 410
TYR A 249
ARG A 350
 None
 0.87A 1gtbA-4zelA:
undetectable		 1gtbA-4zelA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zhj MG-CHELATASE SUBUNIT
CHLH

(Synechocystis
sp. PCC 6803) 		PF02514
(CobN-Mg_chel)
PF11965
(DUF3479) 		3 GLN A1160
TYR A1125
ARG A1128
 None
 0.90A 1gtbA-4zhjA:
3.3		 1gtbA-4zhjA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE

(Caulobacter
vibrioides) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		3 GLN A 136
TYR A 250
ARG A 251
 None
 0.74A 1gtbA-5a05A:
undetectable		 1gtbA-5a05A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bqc NORRIN
FRIZZLED-4

(Homo sapiens;
Homo sapiens) 		PF00007
(Cys_knot)
PF01392
(Fz) 		3 GLN B  93
TYR A 122
ARG A 121
 None
 0.94A 1gtbA-5bqcB:
undetectable		 1gtbA-5bqcB:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT

(Candidatus
Kuenenia
stuttgartiensis) 		no annotation 3 GLN A 468
TYR A 591
ARG A 297
 None
CL  A 901 ( 2.9A)
None
 0.84A 1gtbA-5c2vA:
undetectable		 1gtbA-5c2vA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cm8 RAS-RELATED PROTEIN
RAL-A

(Drosophila
melanogaster) 		PF00071
(Ras) 		3 GLN B  69
TYR B  48
ARG B  49
 None
 0.92A 1gtbA-5cm8B:
undetectable		 1gtbA-5cm8B:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e7q ACYL-COA SYNTHETASE

(Streptomyces
platensis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		3 GLN A 220
TYR A 325
ARG A 335
 None
 0.89A 1gtbA-5e7qA:
undetectable		 1gtbA-5e7qA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fji BETA-GLUCOSIDASE

(Aspergillus
fumigatus) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		3 GLN A  53
TYR A 343
ARG A 349
 None
EDO  A1871 ( 4.3A)
None
 0.94A 1gtbA-5fjiA:
undetectable		 1gtbA-5fjiA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fuu HIV-1 ENVELOPE
GLYCOPROTEIN GP160

(Human
immunodeficiency
virus 1) 		PF00516
(GP120) 		3 GLN A 428
TYR A 384
ARG A 419
 None
 0.70A 1gtbA-5fuuA:
undetectable		 1gtbA-5fuuA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gy3 GLUCANASE

(Klebsiella
pneumoniae) 		PF01270
(Glyco_hydro_8) 		3 GLN A  55
TYR A  30
ARG A  29
 None
 0.88A 1gtbA-5gy3A:
3.1		 1gtbA-5gy3A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ho9 EXTRACELLULAR
ARABINANASE

(Geobacillus
stearothermophilus) 		PF04616
(Glyco_hydro_43)
PF16369
(GH43_C) 		3 GLN A 477
TYR A 442
ARG A 443
 None
None
SO4  A 711 (-3.1A)
 0.70A 1gtbA-5ho9A:
undetectable		 1gtbA-5ho9A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hp6 EXTRACELLULAR
ARABINANASE

(Geobacillus
stearothermophilus) 		PF04616
(Glyco_hydro_43)
PF13385
(Laminin_G_3)
PF16369
(GH43_C) 		3 GLN A 477
TYR A 442
ARG A 443
 None
 0.70A 1gtbA-5hp6A:
undetectable		 1gtbA-5hp6A:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikp GLYCOGEN
PHOSPHORYLASE, BRAIN
FORM

(Homo sapiens) 		PF00343
(Phosphorylase) 		3 GLN A 539
TYR A 791
ARG A 792
 None
 0.91A 1gtbA-5ikpA:
undetectable		 1gtbA-5ikpA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iv9 LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE

(Klebsiella
pneumoniae;
Klebsiella
pneumoniae) 		PF03968
(OstA)
PF04453
(OstA_C)
PF04390
(LptE) 		3 GLN A 626
TYR B 123
ARG B 124
 None
 0.90A 1gtbA-5iv9A:
undetectable		 1gtbA-5iv9A:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j6s ENDOPLASMIC
RETICULUM
AMINOPEPTIDASE 2

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		3 GLN A 375
TYR A 344
ARG A 345
 None
 0.81A 1gtbA-5j6sA:
undetectable		 1gtbA-5j6sA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jqe SUGAR ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN,CASPASE-8
CHIMERA

(Escherichia
coli) 		PF01335
(DED)
PF13416
(SBP_bac_8) 		3 GLN A 347
TYR A 111
ARG A 110
 None
 0.94A 1gtbA-5jqeA:
undetectable		 1gtbA-5jqeA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n4a INTRAFLAGELLAR
TRANSPORT PROTEIN 80

(Chlamydomonas
reinhardtii) 		no annotation 3 GLN A 559
TYR A 260
ARG A   2
 GOL  A 814 (-3.6A)
None
None
 0.94A 1gtbA-5n4aA:
undetectable		 1gtbA-5n4aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nnn CTATC

(Chaetomium
thermophilum) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		3 GLN A2037
TYR A1999
ARG A2053
 None
 0.82A 1gtbA-5nnnA:
undetectable		 1gtbA-5nnnA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nws SAACMM

(Streptomyces
antibioticus) 		no annotation 3 GLN A 368
TYR A  66
ARG A  44
 None
 0.80A 1gtbA-5nwsA:
undetectable		 1gtbA-5nwsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opj RHAMNOGALACTURONAN
LYASE

(Bacteroides
thetaiotaomicron) 		no annotation 3 GLN A 461
TYR A 379
ARG A 376
 None
 0.78A 1gtbA-5opjA:
1.8		 1gtbA-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t1d GLYCOPROTEIN 42

(Human
gammaherpesvirus
4) 		no annotation 3 GLN C  92
TYR C 167
ARG C 168
 None
 0.96A 1gtbA-5t1dC:
undetectable		 1gtbA-5t1dC:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v4n ALPHA3(135-145)-HLA-
DRB1*01:01

(Homo sapiens) 		PF00969
(MHC_II_beta)
PF07654
(C1-set) 		3 GLN C 319
TYR C 296
ARG C 288
 None
 0.95A 1gtbA-5v4nC:
undetectable		 1gtbA-5v4nC:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7a ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT

(Oryctolagus
cuniculus) 		no annotation 3 GLN B 572
TYR B 319
ARG B 321
 None
 0.93A 1gtbA-5w7aB:
undetectable		 1gtbA-5w7aB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7c ACYLOXYACYL
HYDROLASE

(Homo sapiens) 		no annotation 3 GLN C 572
TYR C 320
ARG C 322
 None
 0.93A 1gtbA-5w7cC:
undetectable		 1gtbA-5w7cC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wax -

(-) 		no annotation 3 GLN A 295
TYR A  13
ARG A  28
 None
 0.95A 1gtbA-5waxA:
undetectable		 1gtbA-5waxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wgx FLAVIN-DEPENDENT
HALOGENASE

(Malbranchea
aurantiaca) 		PF04820
(Trp_halogenase) 		3 GLN A 488
TYR A 474
ARG A 475
 None
 0.67A 1gtbA-5wgxA:
undetectable		 1gtbA-5wgxA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y5a KLLA0F20702P

(Kluyveromyces
lactis) 		no annotation 3 GLN A  99
TYR A 213
ARG A 212
 None
 0.85A 1gtbA-5y5aA:
2.1		 1gtbA-5y5aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c1d UNCONVENTIONAL
MYOSIN-IB

(Rattus
norvegicus) 		no annotation 3 GLN P 615
TYR P  58
ARG P  59
 None
 0.87A 1gtbA-6c1dP:
undetectable		 1gtbA-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfw MONOVALENT CATION/H+
ANTIPORTER SUBUNIT F
MBH SUBUNIT

(Pyrococcus
furiosus;
Pyrococcus
furiosus) 		no annotation
no annotation 		3 GLN D  19
TYR B  52
ARG B  54
 None
 0.64A 1gtbA-6cfwD:
undetectable		 1gtbA-6cfwD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dw1


(;
) 		no annotation
no annotation 		3 GLN E  64
TYR D 220
ARG D 176
 None
 0.80A 1gtbA-6dw1E:
undetectable		 1gtbA-6dw1E:
undetectable