SIMILAR PATTERNS OF AMINO ACIDS FOR 1GEB_A_CAMA418_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b0a | PROTEIN (FOLDBIFUNCTIONALPROTEIN) (Escherichiacoli) |
PF00763(THF_DHG_CYH)PF02882(THF_DHG_CYH_C) | 5 | THR A 74LEU A 70VAL A 39ILE A 83VAL A 110 | None | 1.42A | 1gebA-1b0aA:0.0 | 1gebA-1b0aA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d2e | ELONGATION FACTOR TU(EF-TU) (Bos taurus) |
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2) | 5 | THR A 117VAL A 236ILE A 216VAL A 177ILE A 148 | None | 1.08A | 1gebA-1d2eA:0.0 | 1gebA-1d2eA:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d2e | ELONGATION FACTOR TU(EF-TU) (Bos taurus) |
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2) | 5 | TYR A 115VAL A 236ILE A 216VAL A 177ILE A 148 | None | 1.17A | 1gebA-1d2eA:0.0 | 1gebA-1d2eA:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d7q | TRANSLATIONINITIATION FACTOR 1A (Homo sapiens) |
PF01176(eIF-1a) | 5 | VAL A 82ILE A 90VAL A 92ASP A 103ILE A 105 | None | 1.35A | 1gebA-1d7qA:undetectable | 1gebA-1d7qA:16.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f3g | GLUCOSE-SPECIFICPHOSPHOCARRIERPROTEIN IIAGLC (Escherichiacoli) |
PF00358(PTS_EIIA_1) | 5 | PHE A 77VAL A 138ILE A 22VAL A 63ILE A 79 | None | 1.39A | 1gebA-1f3gA:undetectable | 1gebA-1f3gA:17.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1flz | URACIL-DNAGLYCOSYLASE (Escherichiacoli) |
PF03167(UDG) | 5 | THR A 124LEU A 61ILE A 152ASP A 146ILE A 174 | None | 1.39A | 1gebA-1flzA:0.0 | 1gebA-1flzA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h4p | GLUCAN1,3-BETA-GLUCOSIDASEI/II (Saccharomycescerevisiae) |
PF00150(Cellulase) | 5 | PHE A 139TYR A 210ILE A 160VAL A 172ILE A 134 | None | 1.36A | 1gebA-1h4pA:0.0 | 1gebA-1h4pA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hvy | THYMIDYLATE SYNTHASE (Homo sapiens) |
PF00303(Thymidylat_synt) | 5 | PHE A 296ILE A 240VAL A 285ASP A 295ILE A 281 | None | 1.19A | 1gebA-1hvyA:0.0 | 1gebA-1hvyA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ib8 | CONSERVED PROTEINSP14.3 (Streptococcuspneumoniae) |
PF02576(DUF150)PF17384(DUF150_C) | 5 | PHE A 76TYR A 80ILE A 31VAL A 14ILE A 10 | None | 1.36A | 1gebA-1ib8A:0.0 | 1gebA-1ib8A:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mhs | PLASMA MEMBRANEATPASE (Neurosporacrassa) |
PF00122(E1-E2_ATPase)PF00690(Cation_ATPase_N)PF00702(Hydrolase) | 5 | PHE A 685LEU A 761VAL A 692ILE A 293VAL A 289 | None | 1.35A | 1gebA-1mhsA:0.0 | 1gebA-1mhsA:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nba | N-CARBAMOYLSARCOSINEAMIDOHYDROLASE (Arthrobactersp.) |
PF00857(Isochorismatase) | 5 | LEU A 234VAL A 87ILE A 168ASP A 165ILE A 164 | None | 1.36A | 1gebA-1nbaA:undetectable | 1gebA-1nbaA:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pio | BETA-LACTAMASE (Staphylococcusaureus) |
PF13354(Beta-lactamase2) | 5 | TYR A 68LEU A 169ILE A 139VAL A 148ILE A 75 | None | 1.35A | 1gebA-1pioA:undetectable | 1gebA-1pioA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1poi | GLUTACONATE COENZYMEA-TRANSFERASE (Acidaminococcusfermentans) |
PF01144(CoA_trans) | 5 | LEU A 40VAL A 36ILE A 11VAL A 15ILE A 21 | None | 1.33A | 1gebA-1poiA:undetectable | 1gebA-1poiA:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qwg | (2R)-PHOSPHO-3-SULFOLACTATE SYNTHASE (Methanocaldococcusjannaschii) |
PF02679(ComA) | 5 | PHE A 219LEU A 178ILE A 154VAL A 197ILE A 199 | None | 0.95A | 1gebA-1qwgA:undetectable | 1gebA-1qwgA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tc5 | PROBABLE EUKARYOTICD-AMINO ACID TRNADEACYLASE,LMAJ005534AAA (Leishmaniamajor) |
PF02580(Tyr_Deacylase) | 5 | LEU A 66VAL A 62ILE A 194VAL A 13ILE A 42 | None | 1.43A | 1gebA-1tc5A:undetectable | 1gebA-1tc5A:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tyd | TYROSYL-TRNASYNTHETASE (Geobacillusstearothermophilus) |
PF00579(tRNA-synt_1b) | 5 | PHE E 231THR E 258LEU E 298VAL E 302ILE E 46 | None | 1.28A | 1gebA-1tydE:undetectable | 1gebA-1tydE:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vbm | TYROSYL-TRNASYNTHETASE (Escherichiacoli) |
PF00579(tRNA-synt_1b) | 5 | PHE A 236THR A 263LEU A 303VAL A 307VAL A 244 | None | 1.34A | 1gebA-1vbmA:undetectable | 1gebA-1vbmA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ycd | HYPOTHETICAL 27.3KDA PROTEIN INAAP1-SMF2 INTERGENICREGION (Saccharomycescerevisiae) |
PF03959(FSH1) | 5 | PHE A 10TYR A 41VAL A 220ILE A 227VAL A 231 | None | 1.21A | 1gebA-1ycdA:undetectable | 1gebA-1ycdA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zcl | PROTEIN TYROSINEPHOSPHATASE 4A1 (Rattusnorvegicus) |
PF00782(DSPc) | 5 | PHE A 92LEU A 119ILE A 21VAL A 102ILE A 100 | None | 1.36A | 1gebA-1zclA:undetectable | 1gebA-1zclA:18.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zcl | PROTEIN TYROSINEPHOSPHATASE 4A1 (Rattusnorvegicus) |
PF00782(DSPc) | 5 | PHE A 92VAL A 12ILE A 21VAL A 102ILE A 100 | None | 1.34A | 1gebA-1zclA:undetectable | 1gebA-1zclA:18.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a6o | ISHP608 TRANSPOSASE (Helicobacterpylori) |
PF01797(Y1_Tnp) | 5 | THR A 83LEU A 51VAL A 53ILE A 55ILE A 21 | None | 1.07A | 1gebA-2a6oA:undetectable | 1gebA-2a6oA:16.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2avt | DNA POLYMERASE IIIBETA SUBUNIT (Streptococcuspyogenes) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 5 | PHE A 175LEU A 135ILE A 231VAL A 201ILE A 167 | None | 1.40A | 1gebA-2avtA:undetectable | 1gebA-2avtA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2awa | DNA POLYMERASE III,BETA CHAIN (Streptococcuspneumoniae) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 5 | PHE A 11LEU A 77VAL A 34VAL A 38ILE A 43 | None | 1.11A | 1gebA-2awaA:undetectable | 1gebA-2awaA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d7s | RNA-DEPENDENT RNAPOLYMERASE (Foot-and-mouthdisease virus) |
PF00680(RdRP_1) | 5 | TYR A 331LEU A 319ILE A 364VAL A 239ILE A 340 | None | 1.40A | 1gebA-2d7sA:undetectable | 1gebA-2d7sA:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dkj | SERINEHYDROXYMETHYLTRANSFERASE (Thermusthermophilus) |
PF00464(SHMT) | 5 | PHE A 314VAL A 377ILE A 337VAL A 339ILE A 359 | None | 1.29A | 1gebA-2dkjA:undetectable | 1gebA-2dkjA:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hiv | THERMOSTABLE DNALIGASE (Sulfolobussolfataricus) |
PF01068(DNA_ligase_A_M)PF04675(DNA_ligase_A_N)PF04679(DNA_ligase_A_C) | 5 | LEU A 30VAL A 42ILE A 44VAL A 121ILE A 37 | None | 1.14A | 1gebA-2hivA:undetectable | 1gebA-2hivA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2la6 | RNA-BINDING PROTEINFUS (Homo sapiens) |
PF00076(RRM_1) | 5 | PHE A 70VAL A 30ILE A 93VAL A 95ILE A 16 | None | 1.29A | 1gebA-2la6A:undetectable | 1gebA-2la6A:13.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2m56 | CAMPHOR5-MONOOXYGENASE (Pseudomonasputida) |
PF00067(p450) | 5 | PHE A 87TYR A 96LEU A 244VAL A 396ILE A 395 | CAM A 502 (-4.6A)CAM A 502 (-4.5A)HEM A 501 (-4.5A)NoneNone | 1.07A | 1gebA-2m56A:67.6 | 1gebA-2m56A:99.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2m56 | CAMPHOR5-MONOOXYGENASE (Pseudomonasputida) |
PF00067(p450) | 8 | PHE A 87TYR A 96THR A 101LEU A 244VAL A 247VAL A 295ASP A 297ILE A 395 | CAM A 502 (-4.6A)CAM A 502 (-4.5A)HEM A 501 (-2.9A)HEM A 501 (-4.5A)NoneHEM A 501 (-4.6A)HEM A 501 (-2.8A)None | 0.31A | 1gebA-2m56A:67.6 | 1gebA-2m56A:99.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o4j | VITAMIN D3 RECEPTOR (Rattusnorvegicus) |
PF00104(Hormone_recep) | 5 | THR A 358LEU A 328VAL A 327ILE A 244ILE A 134 | None | 1.34A | 1gebA-2o4jA:undetectable | 1gebA-2o4jA:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2odl | ADHESIN (Haemophilusinfluenzae) |
PF05860(Haemagg_act) | 5 | LEU A 343VAL A 381ILE A 403VAL A 392ILE A 391 | None | 1.32A | 1gebA-2odlA:undetectable | 1gebA-2odlA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qh9 | UPF0215 PROTEINAF_1433 (Archaeoglobusfulgidus) |
PF01949(DUF99) | 5 | LEU A 67VAL A 91ILE A 89VAL A 53ILE A 50 | None | 1.42A | 1gebA-2qh9A:undetectable | 1gebA-2qh9A:16.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ts1 | TYROSYL-TRNASYNTHETASE (Geobacillusstearothermophilus) |
PF00579(tRNA-synt_1b) | 5 | PHE A 231THR A 258LEU A 298VAL A 302ILE A 46 | None | 1.29A | 1gebA-2ts1A:undetectable | 1gebA-2ts1A:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yyz | SUGAR ABCTRANSPORTER,ATP-BINDING PROTEIN (Thermotogamaritima) |
PF00005(ABC_tran)PF08402(TOBE_2) | 5 | PHE A 207LEU A 9VAL A 6ILE A 4VAL A 188 | None | 1.22A | 1gebA-2yyzA:undetectable | 1gebA-2yyzA:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yz0 | SERINE/THREONINE-PROTEIN KINASE GCN2 (Saccharomycescerevisiae) |
PF05773(RWD) | 5 | PHE A 68THR A 121LEU A 52ILE A 25ILE A 114 | None | 1.07A | 1gebA-2yz0A:undetectable | 1gebA-2yz0A:15.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zle | PROTEASE DO (Escherichiacoli) |
PF00595(PDZ)PF13365(Trypsin_2) | 5 | THR A 127LEU A 169ILE A 160ASP A 157ILE A 193 | None | 1.10A | 1gebA-2zleA:undetectable | 1gebA-2zleA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dm0 | MALTOSE-BINDINGPERIPLASMIC PROTEINFUSED WITH RACK1 (Escherichiacoli;Arabidopsisthaliana) |
PF00400(WD40)PF01547(SBP_bac_1) | 5 | THR A1189LEU A1186ILE A1129VAL A1153ASP A1173 | None | 0.96A | 1gebA-3dm0A:undetectable | 1gebA-3dm0A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dx5 | UNCHARACTERIZEDPROTEIN ASBF (Bacillusanthracis) |
PF01261(AP_endonuc_2) | 5 | TYR A 121LEU A 158VAL A 162VAL A 139ILE A 128 | None | 1.39A | 1gebA-3dx5A:undetectable | 1gebA-3dx5A:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e81 | ACYLNEURAMINATECYTIDYLYLTRANSFERASE (Bacteroidesthetaiotaomicron) |
PF08282(Hydrolase_3) | 5 | LEU A 111VAL A 114ILE A 116VAL A 151ILE A 7 | None | 1.27A | 1gebA-3e81A:undetectable | 1gebA-3e81A:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ee1 | EFFECTOR PROTEINVIRA (Shigellaflexneri) |
PF06872(EspG) | 5 | PHE A 278THR A 198LEU A 209ASP A 189ILE A 186 | None | 1.39A | 1gebA-3ee1A:undetectable | 1gebA-3ee1A:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3enk | UDP-GLUCOSE4-EPIMERASE (Burkholderiapseudomallei) |
PF16363(GDP_Man_Dehyd) | 5 | LEU A 111VAL A 63ILE A 72VAL A 32ILE A 33 | NoneNAD A 341 (-3.6A)NoneNoneNone | 1.18A | 1gebA-3enkA:undetectable | 1gebA-3enkA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fww | BIFUNCTIONAL PROTEINGLMU (Yersinia pestis) |
PF00132(Hexapep)PF12804(NTP_transf_3) | 5 | THR A 65LEU A 27VAL A 26ASP A 68ILE A 40 | None | 1.39A | 1gebA-3fwwA:undetectable | 1gebA-3fwwA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gf8 | PUTATIVEPOLYSACCHARIDEBINDING PROTEINS(DUF1812) (Bacteroidesthetaiotaomicron) |
PF08842(Mfa2) | 5 | PHE A 292LEU A 248ILE A 195VAL A 173ILE A 290 | None | 1.35A | 1gebA-3gf8A:undetectable | 1gebA-3gf8A:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gwj | ARYLPHORIN (Antheraeapernyi) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 5 | PHE A 559ILE A 552VAL A 511ASP A 539ILE A 513 | None | 1.42A | 1gebA-3gwjA:undetectable | 1gebA-3gwjA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hb0 | EYES ABSENT HOMOLOG2 (DROSOPHILA) (Homo sapiens) |
PF00702(Hydrolase) | 5 | THR A 447LEU A 275VAL A 458ILE A 312ILE A 452 | BEF A 801 (-3.7A)BEF A 801 (-4.2A)NoneNoneNone | 1.37A | 1gebA-3hb0A:undetectable | 1gebA-3hb0A:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hhs | PHENOLOXIDASESUBUNIT 1 (Manduca sexta) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 5 | VAL B 486ILE B 542VAL B 501ASP B 529ILE B 503 | None | 1.42A | 1gebA-3hhsB:undetectable | 1gebA-3hhsB:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hhs | PHENOLOXIDASESUBUNIT 2 (Manduca sexta) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 5 | VAL A 493ILE A 548VAL A 507ASP A 535ILE A 509 | None | 1.36A | 1gebA-3hhsA:undetectable | 1gebA-3hhsA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ifq | PLAKOGLOBIN (Homo sapiens) |
PF00514(Arm) | 5 | THR A 501LEU A 488ILE A 439VAL A 476ILE A 482 | None | 1.10A | 1gebA-3ifqA:undetectable | 1gebA-3ifqA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ihy | PHOSPHATIDYLINOSITOL3-KINASE CATALYTICSUBUNIT TYPE 3 (Homo sapiens) |
PF00454(PI3_PI4_kinase)PF00613(PI3Ka) | 5 | LEU A 641VAL A 672ILE A 634ASP A 761ILE A 760 | None | 1.42A | 1gebA-3ihyA:undetectable | 1gebA-3ihyA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jtw | DIHYDROFOLATEREDUCTASE (Pediococcuspentosaceus) |
PF01872(RibD_C) | 5 | THR A 49VAL A 115ILE A 120VAL A 79ILE A 78 | NoneNoneSO4 A 179 ( 4.9A)NoneNone | 1.19A | 1gebA-3jtwA:undetectable | 1gebA-3jtwA:17.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ob8 | BETA-GALACTOSIDASE (Kluyveromyceslactis) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF02929(Bgal_small_N) | 5 | THR A 666LEU A 685VAL A 691VAL A 700ILE A 680 | None | 1.28A | 1gebA-3ob8A:undetectable | 1gebA-3ob8A:16.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pzl | AGMATINEUREOHYDROLASE (Thermoplasmavolcanium) |
PF00491(Arginase) | 5 | PHE A 268VAL A 254VAL A 271ASP A 269ILE A 270 | None | 1.43A | 1gebA-3pzlA:undetectable | 1gebA-3pzlA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s5s | MANDELATERACEMASE/MUCONATELACTONIZING ENZYMEFAMILY PROTEIN (Sorangiumcellulosum) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | LEU A 199VAL A 167ILE A 179VAL A 218ILE A 192 | None | 1.39A | 1gebA-3s5sA:undetectable | 1gebA-3s5sA:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wgp | VITAMIN D3 RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | THR A 362LEU A 332VAL A 331ILE A 248ILE A 134 | None | 1.31A | 1gebA-3wgpA:undetectable | 1gebA-3wgpA:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2p | RETINOIC ACIDINDUCIBLE PROTEIN I (Anasplatyrhynchos) |
PF00270(DEAD)PF00271(Helicase_C) | 5 | PHE A 369LEU A 299ILE A 327VAL A 337ILE A 341 | None | 1.02A | 1gebA-4a2pA:undetectable | 1gebA-4a2pA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2p | RETINOIC ACIDINDUCIBLE PROTEIN I (Anasplatyrhynchos) |
PF00270(DEAD)PF00271(Helicase_C) | 5 | PHE A 369LEU A 389ILE A 353VAL A 337ILE A 341 | None | 1.33A | 1gebA-4a2pA:undetectable | 1gebA-4a2pA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2q | RETINOIC ACIDINDUCIBLE PROTEIN I (Anasplatyrhynchos) |
PF00270(DEAD)PF00271(Helicase_C)PF16739(CARD_2) | 5 | PHE A 369LEU A 389ILE A 353VAL A 337ILE A 341 | None | 1.22A | 1gebA-4a2qA:undetectable | 1gebA-4a2qA:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2w | RETINOIC ACIDINDUCIBLE PROTEIN I (Anasplatyrhynchos) |
PF00270(DEAD)PF00271(Helicase_C)PF16739(CARD_2) | 5 | PHE A 369LEU A 389ILE A 353VAL A 337ILE A 341 | None | 1.28A | 1gebA-4a2wA:undetectable | 1gebA-4a2wA:18.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bps | FKBO (Streptomyceshygroscopicus) |
no annotation | 5 | PHE A 123TYR A 119THR A 137VAL A 225ILE A 171 | None | 1.17A | 1gebA-4bpsA:undetectable | 1gebA-4bpsA:21.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c9m | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 6 | TYR A 98THR A 103LEU A 252VAL A 303ASP A 305ILE A 403 | NoneGOL A1419 (-3.8A)HEM A1418 (-4.0A)GOL A1419 (-3.9A)HEM A1418 (-2.7A)None | 0.61A | 1gebA-4c9mA:58.5 | 1gebA-4c9mA:44.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d6v | G PROTEIN BETASUBUNIT GIB2 (Cryptococcusneoformans) |
PF00400(WD40) | 5 | THR A 187LEU A 184ILE A 129VAL A 151ASP A 171 | None | 0.92A | 1gebA-4d6vA:undetectable | 1gebA-4d6vA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fuu | LEUCINEAMINOPEPTIDASE (Bacteroidesthetaiotaomicron) |
PF04389(Peptidase_M28) | 5 | PHE A 218LEU A 121ILE A 288VAL A 249ILE A 245 | None | 1.34A | 1gebA-4fuuA:undetectable | 1gebA-4fuuA:23.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gk9 | AGGLUTININ (BOA) (Burkholderiaoklahomensis) |
no annotation | 5 | PHE A 269VAL A 241ILE A 179VAL A 177ILE A 246 | None | 1.27A | 1gebA-4gk9A:undetectable | 1gebA-4gk9A:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j0q | ELONGATION FACTORTU-A (Pseudomonasputida) |
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2) | 5 | TYR A 70VAL A 192ILE A 171VAL A 132ILE A 103 | None | 1.13A | 1gebA-4j0qA:undetectable | 1gebA-4j0qA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j3b | M1 FAMILYAMINOPEPTIDASE (Plasmodiumfalciparum) |
PF01433(Peptidase_M1)PF11940(DUF3458)PF17432(DUF3458_C) | 5 | LEU A 307VAL A 387ILE A 469VAL A 454ILE A 313 | None | 1.34A | 1gebA-4j3bA:undetectable | 1gebA-4j3bA:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jn7 | ENOLASE (Agrobacteriumtumefaciens) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | VAL A 289ILE A 278VAL A 269ASP A 265ILE A 266 | None | 1.36A | 1gebA-4jn7A:undetectable | 1gebA-4jn7A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kvs | ALDEHYDEDECARBONYLASE (Prochlorococcusmarinus) |
PF11266(Ald_deCOase) | 5 | TYR A 30LEU A 87VAL A 89VAL A 41ILE A 37 | NoneNoneNone6NA A 301 ( 4.2A)None | 1.17A | 1gebA-4kvsA:undetectable | 1gebA-4kvsA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l37 | ARYLPHORIN (Bombyx mori) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 5 | PHE B 558ILE B 551VAL B 510ASP B 538ILE B 512 | None | 1.34A | 1gebA-4l37B:undetectable | 1gebA-4l37B:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lun | NONSENSE-MEDIATEDMRNA DECAY PROTEIN 2 (Saccharomycescerevisiae) |
PF02854(MIF4G) | 5 | PHE U 40LEU U 57ILE U 97VAL U 76ILE U 72 | None | 1.40A | 1gebA-4lunU:undetectable | 1gebA-4lunU:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q1z | PUTATIVE LIPOPROTEIN (Bacteroidesthetaiotaomicron) |
PF16215(DUF4876) | 5 | PHE A 224TYR A 256THR A 258ILE A 267ILE A 197 | None | 1.35A | 1gebA-4q1zA:undetectable | 1gebA-4q1zA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r3u | 2-HYDROXYISOBUTYRYL-COA MUTASE LARGESUBUNIT (Aquincolatertiaricarbonis) |
PF01642(MM_CoA_mutase) | 5 | PHE A 287TYR A 309VAL A 268ILE A 226ILE A 241 | None | 1.27A | 1gebA-4r3uA:undetectable | 1gebA-4r3uA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rk6 | GLUCOSE-RESISTANCEAMYLASE REGULATOR (Weissellaparamesenteroides) |
PF13377(Peripla_BP_3) | 5 | THR A 86LEU A 93VAL A 65ILE A 78ILE A 143 | None | 1.37A | 1gebA-4rk6A:undetectable | 1gebA-4rk6A:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4txd | CSC2 (Thermofilumpendens) |
no annotation | 5 | THR A 85LEU A 249VAL A 264ILE A 266VAL A 39 | None | 1.00A | 1gebA-4txdA:undetectable | 1gebA-4txdA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w8l | ENDO-1,4-BETA-XYLANASE C (Paenibacillusbarcinonensis) |
PF00331(Glyco_hydro_10) | 5 | VAL A 546ILE A 509VAL A 476ASP A 529ILE A 477 | None | 1.38A | 1gebA-4w8lA:undetectable | 1gebA-4w8lA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x2d | FIC FAMILY PROTEINPUTATIVEFILAMENTATIONINDUCED BY CAMPPROTEIN (Clostridioidesdifficile) |
PF02661(Fic) | 5 | PHE A 165TYR A 110LEU A 134VAL A 176ILE A 172 | None | 1.43A | 1gebA-4x2dA:undetectable | 1gebA-4x2dA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xyb | FORMATEDEHYDROGENASE (Granulicellamallensis) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | LEU A 208VAL A 207ILE A 159VAL A 251ILE A 252 | None | 1.42A | 1gebA-4xybA:undetectable | 1gebA-4xybA:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y9v | PARTICLE-ASSOCIATEDLYASE (Acinetobactervirus AP22) |
no annotation | 5 | PHE A 194LEU A 179ILE A 164VAL A 188ILE A 192 | None | 1.34A | 1gebA-4y9vA:undetectable | 1gebA-4y9vA:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z5s | ALDEHYDEDECARBONYLASE (Synechocystissp. PCC 6803) |
PF11266(Ald_deCOase) | 5 | TYR A 17LEU A 74VAL A 76VAL A 28ILE A 24 | None | 1.26A | 1gebA-4z5sA:undetectable | 1gebA-4z5sA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z96 | UBIQUITINCARBOXYL-TERMINALHYDROLASE 7 (Homo sapiens) |
PF12436(USP7_ICP0_bdg)PF14533(USP7_C2) | 5 | PHE A 903LEU A1009VAL A 992ILE A 949ILE A1005 | None | 1.42A | 1gebA-4z96A:undetectable | 1gebA-4z96A:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a31 | ANAPHASE-PROMOTINGCOMPLEX SUBUNIT 1 (Homo sapiens) |
PF12859(ANAPC1) | 5 | THR A 433VAL A 490ILE A 587VAL A 595ILE A 609 | None | 1.33A | 1gebA-5a31A:undetectable | 1gebA-5a31A:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a31 | ANAPHASE-PROMOTINGCOMPLEX SUBUNIT 1 (Homo sapiens) |
PF12859(ANAPC1) | 5 | TYR A 642THR A 487LEU A 499VAL A 509ILE A 607 | None | 1.32A | 1gebA-5a31A:undetectable | 1gebA-5a31A:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5by6 | THYMIDYLATE SYNTHASE (Trichinellaspiralis) |
PF00303(Thymidylat_synt) | 5 | PHE A 290ILE A 234VAL A 279ASP A 289ILE A 275 | None | 1.29A | 1gebA-5by6A:undetectable | 1gebA-5by6A:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d1r | RV1816TRANSCRIPTIONALREGULATOR (Mycobacteriumtuberculosis) |
PF00440(TetR_N) | 5 | LEU A 66VAL A 22ILE A 42VAL A 53ILE A 17 | None | 1.40A | 1gebA-5d1rA:undetectable | 1gebA-5d1rA:19.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hvn | 3-DEHYDROQUINATESYNTHASE (Francisellatularensis) |
PF01761(DHQ_synthase) | 5 | THR A 86LEU A 38VAL A 39ILE A 107ILE A 67 | None | 1.18A | 1gebA-5hvnA:undetectable | 1gebA-5hvnA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i1w | CRMK (Actinoalloteichussp. WH1-2216-6) |
PF01565(FAD_binding_4)PF08031(BBE) | 5 | PHE A 34TYR A 16VAL A 28VAL A 75ILE A 78 | None | 1.40A | 1gebA-5i1wA:undetectable | 1gebA-5i1wA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ipy | FLAVIN-CONTAININGMONOOXYGENASE (Roseovariusnubinhibens) |
PF00743(FMO-like) | 5 | PHE A 189TYR A 67ILE A 224VAL A 202ILE A 269 | None | 1.14A | 1gebA-5ipyA:undetectable | 1gebA-5ipyA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k52 | ALDEHYDEDECARBONYLASE (Limnothrix sp.KNUA012) |
PF11266(Ald_deCOase) | 5 | TYR A 17LEU A 74VAL A 76VAL A 28ILE A 24 | NoneNoneNoneOCD A 500 ( 4.6A)OCD A 500 (-4.6A) | 1.20A | 1gebA-5k52A:undetectable | 1gebA-5k52A:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k53 | ALDEHYDEDEFORMYLATINGOXYGENASE (Oscillatoriasp.) |
PF11266(Ald_deCOase) | 5 | TYR A 17LEU A 74VAL A 76VAL A 28ILE A 24 | NoneNoneNoneSTE A 502 ( 4.8A)STE A 502 (-4.4A) | 1.11A | 1gebA-5k53A:undetectable | 1gebA-5k53A:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lcw | ANAPHASE-PROMOTINGCOMPLEX SUBUNIT 1 (Homo sapiens) |
PF12859(ANAPC1) | 5 | THR A 433VAL A 490ILE A 587VAL A 595ILE A 609 | None | 1.27A | 1gebA-5lcwA:undetectable | 1gebA-5lcwA:11.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lcw | ANAPHASE-PROMOTINGCOMPLEX SUBUNIT 1 (Homo sapiens) |
PF12859(ANAPC1) | 5 | TYR A 642THR A 487LEU A 499VAL A 509ILE A 607 | None | 1.28A | 1gebA-5lcwA:undetectable | 1gebA-5lcwA:11.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mal | LIPASE (Streptomycesrimosus) |
PF13472(Lipase_GDSL_2) | 5 | THR A 174LEU A 120VAL A 123ILE A 127VAL A 136 | None | 1.37A | 1gebA-5malA:undetectable | 1gebA-5malA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u3c | CTP SYNTHASE (Escherichiacoli) |
PF00117(GATase)PF06418(CTP_synth_N) | 5 | LEU A 341VAL A 333VAL A 384ASP A 388ILE A 362 | None | 1.37A | 1gebA-5u3cA:undetectable | 1gebA-5u3cA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u8e | ARGININE KINASE (Polybetespythagoricus) |
PF00217(ATP-gua_Ptrans)PF02807(ATP-gua_PtransN) | 5 | TYR A 75THR A 269LEU A 275VAL A 65ILE A 67 | None | 1.38A | 1gebA-5u8eA:undetectable | 1gebA-5u8eA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uqi | PHOSPHOSUGARISOMERASE (Escherichiacoli) |
no annotation | 5 | PHE A 48THR A 70LEU A 172VAL A 168ILE A 95 | None | 1.42A | 1gebA-5uqiA:undetectable | 1gebA-5uqiA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ur0 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Naegleriagruberi) |
no annotation | 5 | PHE A 9LEU A 58VAL A 67VAL A 74ILE A 31 | None | 1.28A | 1gebA-5ur0A:undetectable | 1gebA-5ur0A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y37 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Streptococcusagalactiae) |
no annotation | 5 | THR A 125LEU A 328ILE A 25VAL A 9ILE A 96 | NAD A 401 (-4.2A)NoneNoneNoneNone | 1.29A | 1gebA-5y37A:undetectable | 1gebA-5y37A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z0c | NEROL DEHYDROGENASE (Persicariaminor) |
no annotation | 5 | PHE A 358LEU A 70ILE A 75ASP A 141ILE A 354 | None | 1.36A | 1gebA-5z0cA:undetectable | 1gebA-5z0cA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c0b | TOXIN B (Clostridioidesdifficile) |
no annotation | 5 | TYR A1724LEU A1780VAL A1731ILE A1704ILE A1674 | None | 1.30A | 1gebA-6c0bA:undetectable | 1gebA-6c0bA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cqo | SINGLE-STRANDEDDNA-BINDING PROTEINRIM1, MITOCHONDRIAL (Saccharomycescerevisiae) |
no annotation | 5 | LEU A 44VAL A 65ILE A 113VAL A 84ILE A 48 | None | 1.36A | 1gebA-6cqoA:undetectable | 1gebA-6cqoA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eu6 | AMMONIUM TRANSPORTER (CandidatusKueneniastuttgartiensis) |
no annotation | 5 | PHE A 34TYR A 30THR A 213LEU A 274VAL A 325 | None | 1.36A | 1gebA-6eu6A:undetectable | 1gebA-6eu6A:undetectable |