SIMILAR PATTERNS OF AMINO ACIDS FOR 1GEB_A_CAMA418

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b0a PROTEIN (FOLD
BIFUNCTIONAL
PROTEIN)


(Escherichia
coli)
PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C)
5 THR A  74
LEU A  70
VAL A  39
ILE A  83
VAL A 110
None
1.42A 1gebA-1b0aA:
0.0
1gebA-1b0aA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d2e ELONGATION FACTOR TU
(EF-TU)


(Bos taurus)
PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3)
PF03144
(GTP_EFTU_D2)
5 THR A 117
VAL A 236
ILE A 216
VAL A 177
ILE A 148
None
1.08A 1gebA-1d2eA:
0.0
1gebA-1d2eA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d2e ELONGATION FACTOR TU
(EF-TU)


(Bos taurus)
PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3)
PF03144
(GTP_EFTU_D2)
5 TYR A 115
VAL A 236
ILE A 216
VAL A 177
ILE A 148
None
1.17A 1gebA-1d2eA:
0.0
1gebA-1d2eA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d7q TRANSLATION
INITIATION FACTOR 1A


(Homo sapiens)
PF01176
(eIF-1a)
5 VAL A  82
ILE A  90
VAL A  92
ASP A 103
ILE A 105
None
1.35A 1gebA-1d7qA:
undetectable
1gebA-1d7qA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f3g GLUCOSE-SPECIFIC
PHOSPHOCARRIER
PROTEIN IIAGLC


(Escherichia
coli)
PF00358
(PTS_EIIA_1)
5 PHE A  77
VAL A 138
ILE A  22
VAL A  63
ILE A  79
None
1.39A 1gebA-1f3gA:
undetectable
1gebA-1f3gA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1flz URACIL-DNA
GLYCOSYLASE


(Escherichia
coli)
PF03167
(UDG)
5 THR A 124
LEU A  61
ILE A 152
ASP A 146
ILE A 174
None
1.39A 1gebA-1flzA:
0.0
1gebA-1flzA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h4p GLUCAN
1,3-BETA-GLUCOSIDASE
I/II


(Saccharomyces
cerevisiae)
PF00150
(Cellulase)
5 PHE A 139
TYR A 210
ILE A 160
VAL A 172
ILE A 134
None
1.36A 1gebA-1h4pA:
0.0
1gebA-1h4pA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hvy THYMIDYLATE SYNTHASE

(Homo sapiens)
PF00303
(Thymidylat_synt)
5 PHE A 296
ILE A 240
VAL A 285
ASP A 295
ILE A 281
None
1.19A 1gebA-1hvyA:
0.0
1gebA-1hvyA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ib8 CONSERVED PROTEIN
SP14.3


(Streptococcus
pneumoniae)
PF02576
(DUF150)
PF17384
(DUF150_C)
5 PHE A  76
TYR A  80
ILE A  31
VAL A  14
ILE A  10
None
1.36A 1gebA-1ib8A:
0.0
1gebA-1ib8A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mhs PLASMA MEMBRANE
ATPASE


(Neurospora
crassa)
PF00122
(E1-E2_ATPase)
PF00690
(Cation_ATPase_N)
PF00702
(Hydrolase)
5 PHE A 685
LEU A 761
VAL A 692
ILE A 293
VAL A 289
None
1.35A 1gebA-1mhsA:
0.0
1gebA-1mhsA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nba N-CARBAMOYLSARCOSINE
AMIDOHYDROLASE


(Arthrobacter
sp.)
PF00857
(Isochorismatase)
5 LEU A 234
VAL A  87
ILE A 168
ASP A 165
ILE A 164
None
1.36A 1gebA-1nbaA:
undetectable
1gebA-1nbaA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pio BETA-LACTAMASE

(Staphylococcus
aureus)
PF13354
(Beta-lactamase2)
5 TYR A  68
LEU A 169
ILE A 139
VAL A 148
ILE A  75
None
1.35A 1gebA-1pioA:
undetectable
1gebA-1pioA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1poi GLUTACONATE COENZYME
A-TRANSFERASE


(Acidaminococcus
fermentans)
PF01144
(CoA_trans)
5 LEU A  40
VAL A  36
ILE A  11
VAL A  15
ILE A  21
None
1.33A 1gebA-1poiA:
undetectable
1gebA-1poiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qwg (2R)-PHOSPHO-3-SULFO
LACTATE SYNTHASE


(Methanocaldococcus
jannaschii)
PF02679
(ComA)
5 PHE A 219
LEU A 178
ILE A 154
VAL A 197
ILE A 199
None
0.95A 1gebA-1qwgA:
undetectable
1gebA-1qwgA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tc5 PROBABLE EUKARYOTIC
D-AMINO ACID TRNA
DEACYLASE,
LMAJ005534AAA


(Leishmania
major)
PF02580
(Tyr_Deacylase)
5 LEU A  66
VAL A  62
ILE A 194
VAL A  13
ILE A  42
None
1.43A 1gebA-1tc5A:
undetectable
1gebA-1tc5A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tyd TYROSYL-TRNA
SYNTHETASE


(Geobacillus
stearothermophilus)
PF00579
(tRNA-synt_1b)
5 PHE E 231
THR E 258
LEU E 298
VAL E 302
ILE E  46
None
1.28A 1gebA-1tydE:
undetectable
1gebA-1tydE:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vbm TYROSYL-TRNA
SYNTHETASE


(Escherichia
coli)
PF00579
(tRNA-synt_1b)
5 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
None
1.34A 1gebA-1vbmA:
undetectable
1gebA-1vbmA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ycd HYPOTHETICAL 27.3
KDA PROTEIN IN
AAP1-SMF2 INTERGENIC
REGION


(Saccharomyces
cerevisiae)
PF03959
(FSH1)
5 PHE A  10
TYR A  41
VAL A 220
ILE A 227
VAL A 231
None
1.21A 1gebA-1ycdA:
undetectable
1gebA-1ycdA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zcl PROTEIN TYROSINE
PHOSPHATASE 4A1


(Rattus
norvegicus)
PF00782
(DSPc)
5 PHE A  92
LEU A 119
ILE A  21
VAL A 102
ILE A 100
None
1.36A 1gebA-1zclA:
undetectable
1gebA-1zclA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zcl PROTEIN TYROSINE
PHOSPHATASE 4A1


(Rattus
norvegicus)
PF00782
(DSPc)
5 PHE A  92
VAL A  12
ILE A  21
VAL A 102
ILE A 100
None
1.34A 1gebA-1zclA:
undetectable
1gebA-1zclA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a6o ISHP608 TRANSPOSASE

(Helicobacter
pylori)
PF01797
(Y1_Tnp)
5 THR A  83
LEU A  51
VAL A  53
ILE A  55
ILE A  21
None
1.07A 1gebA-2a6oA:
undetectable
1gebA-2a6oA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2avt DNA POLYMERASE III
BETA SUBUNIT


(Streptococcus
pyogenes)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
5 PHE A 175
LEU A 135
ILE A 231
VAL A 201
ILE A 167
None
1.40A 1gebA-2avtA:
undetectable
1gebA-2avtA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2awa DNA POLYMERASE III,
BETA CHAIN


(Streptococcus
pneumoniae)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
5 PHE A  11
LEU A  77
VAL A  34
VAL A  38
ILE A  43
None
1.11A 1gebA-2awaA:
undetectable
1gebA-2awaA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d7s RNA-DEPENDENT RNA
POLYMERASE


(Foot-and-mouth
disease virus)
PF00680
(RdRP_1)
5 TYR A 331
LEU A 319
ILE A 364
VAL A 239
ILE A 340
None
1.40A 1gebA-2d7sA:
undetectable
1gebA-2d7sA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE


(Thermus
thermophilus)
PF00464
(SHMT)
5 PHE A 314
VAL A 377
ILE A 337
VAL A 339
ILE A 359
None
1.29A 1gebA-2dkjA:
undetectable
1gebA-2dkjA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hiv THERMOSTABLE DNA
LIGASE


(Sulfolobus
solfataricus)
PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C)
5 LEU A  30
VAL A  42
ILE A  44
VAL A 121
ILE A  37
None
1.14A 1gebA-2hivA:
undetectable
1gebA-2hivA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2la6 RNA-BINDING PROTEIN
FUS


(Homo sapiens)
PF00076
(RRM_1)
5 PHE A  70
VAL A  30
ILE A  93
VAL A  95
ILE A  16
None
1.29A 1gebA-2la6A:
undetectable
1gebA-2la6A:
13.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE


(Pseudomonas
putida)
PF00067
(p450)
5 PHE A  87
TYR A  96
LEU A 244
VAL A 396
ILE A 395
CAM  A 502 (-4.6A)
CAM  A 502 (-4.5A)
HEM  A 501 (-4.5A)
None
None
1.07A 1gebA-2m56A:
67.6
1gebA-2m56A:
99.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE


(Pseudomonas
putida)
PF00067
(p450)
8 PHE A  87
TYR A  96
THR A 101
LEU A 244
VAL A 247
VAL A 295
ASP A 297
ILE A 395
CAM  A 502 (-4.6A)
CAM  A 502 (-4.5A)
HEM  A 501 (-2.9A)
HEM  A 501 (-4.5A)
None
HEM  A 501 (-4.6A)
HEM  A 501 (-2.8A)
None
0.31A 1gebA-2m56A:
67.6
1gebA-2m56A:
99.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o4j VITAMIN D3 RECEPTOR

(Rattus
norvegicus)
PF00104
(Hormone_recep)
5 THR A 358
LEU A 328
VAL A 327
ILE A 244
ILE A 134
None
1.34A 1gebA-2o4jA:
undetectable
1gebA-2o4jA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2odl ADHESIN

(Haemophilus
influenzae)
PF05860
(Haemagg_act)
5 LEU A 343
VAL A 381
ILE A 403
VAL A 392
ILE A 391
None
1.32A 1gebA-2odlA:
undetectable
1gebA-2odlA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qh9 UPF0215 PROTEIN
AF_1433


(Archaeoglobus
fulgidus)
PF01949
(DUF99)
5 LEU A  67
VAL A  91
ILE A  89
VAL A  53
ILE A  50
None
1.42A 1gebA-2qh9A:
undetectable
1gebA-2qh9A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ts1 TYROSYL-TRNA
SYNTHETASE


(Geobacillus
stearothermophilus)
PF00579
(tRNA-synt_1b)
5 PHE A 231
THR A 258
LEU A 298
VAL A 302
ILE A  46
None
1.29A 1gebA-2ts1A:
undetectable
1gebA-2ts1A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yyz SUGAR ABC
TRANSPORTER,
ATP-BINDING PROTEIN


(Thermotoga
maritima)
PF00005
(ABC_tran)
PF08402
(TOBE_2)
5 PHE A 207
LEU A   9
VAL A   6
ILE A   4
VAL A 188
None
1.22A 1gebA-2yyzA:
undetectable
1gebA-2yyzA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yz0 SERINE/THREONINE-PRO
TEIN KINASE GCN2


(Saccharomyces
cerevisiae)
PF05773
(RWD)
5 PHE A  68
THR A 121
LEU A  52
ILE A  25
ILE A 114
None
1.07A 1gebA-2yz0A:
undetectable
1gebA-2yz0A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zle PROTEASE DO

(Escherichia
coli)
PF00595
(PDZ)
PF13365
(Trypsin_2)
5 THR A 127
LEU A 169
ILE A 160
ASP A 157
ILE A 193
None
1.10A 1gebA-2zleA:
undetectable
1gebA-2zleA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dm0 MALTOSE-BINDING
PERIPLASMIC PROTEIN
FUSED WITH RACK1


(Escherichia
coli;
Arabidopsis
thaliana)
PF00400
(WD40)
PF01547
(SBP_bac_1)
5 THR A1189
LEU A1186
ILE A1129
VAL A1153
ASP A1173
None
0.96A 1gebA-3dm0A:
undetectable
1gebA-3dm0A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dx5 UNCHARACTERIZED
PROTEIN ASBF


(Bacillus
anthracis)
PF01261
(AP_endonuc_2)
5 TYR A 121
LEU A 158
VAL A 162
VAL A 139
ILE A 128
None
1.39A 1gebA-3dx5A:
undetectable
1gebA-3dx5A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e81 ACYLNEURAMINATE
CYTIDYLYLTRANSFERASE


(Bacteroides
thetaiotaomicron)
PF08282
(Hydrolase_3)
5 LEU A 111
VAL A 114
ILE A 116
VAL A 151
ILE A   7
None
1.27A 1gebA-3e81A:
undetectable
1gebA-3e81A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ee1 EFFECTOR PROTEIN
VIRA


(Shigella
flexneri)
PF06872
(EspG)
5 PHE A 278
THR A 198
LEU A 209
ASP A 189
ILE A 186
None
1.39A 1gebA-3ee1A:
undetectable
1gebA-3ee1A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3enk UDP-GLUCOSE
4-EPIMERASE


(Burkholderia
pseudomallei)
PF16363
(GDP_Man_Dehyd)
5 LEU A 111
VAL A  63
ILE A  72
VAL A  32
ILE A  33
None
NAD  A 341 (-3.6A)
None
None
None
1.18A 1gebA-3enkA:
undetectable
1gebA-3enkA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fww BIFUNCTIONAL PROTEIN
GLMU


(Yersinia pestis)
PF00132
(Hexapep)
PF12804
(NTP_transf_3)
5 THR A  65
LEU A  27
VAL A  26
ASP A  68
ILE A  40
None
1.39A 1gebA-3fwwA:
undetectable
1gebA-3fwwA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)


(Bacteroides
thetaiotaomicron)
PF08842
(Mfa2)
5 PHE A 292
LEU A 248
ILE A 195
VAL A 173
ILE A 290
None
1.35A 1gebA-3gf8A:
undetectable
1gebA-3gf8A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwj ARYLPHORIN

(Antheraea
pernyi)
PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C)
5 PHE A 559
ILE A 552
VAL A 511
ASP A 539
ILE A 513
None
1.42A 1gebA-3gwjA:
undetectable
1gebA-3gwjA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hb0 EYES ABSENT HOMOLOG
2 (DROSOPHILA)


(Homo sapiens)
PF00702
(Hydrolase)
5 THR A 447
LEU A 275
VAL A 458
ILE A 312
ILE A 452
BEF  A 801 (-3.7A)
BEF  A 801 (-4.2A)
None
None
None
1.37A 1gebA-3hb0A:
undetectable
1gebA-3hb0A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhs PHENOLOXIDASE
SUBUNIT 1


(Manduca sexta)
PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C)
5 VAL B 486
ILE B 542
VAL B 501
ASP B 529
ILE B 503
None
1.42A 1gebA-3hhsB:
undetectable
1gebA-3hhsB:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhs PHENOLOXIDASE
SUBUNIT 2


(Manduca sexta)
PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C)
5 VAL A 493
ILE A 548
VAL A 507
ASP A 535
ILE A 509
None
1.36A 1gebA-3hhsA:
undetectable
1gebA-3hhsA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ifq PLAKOGLOBIN

(Homo sapiens)
PF00514
(Arm)
5 THR A 501
LEU A 488
ILE A 439
VAL A 476
ILE A 482
None
1.10A 1gebA-3ifqA:
undetectable
1gebA-3ifqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihy PHOSPHATIDYLINOSITOL
3-KINASE CATALYTIC
SUBUNIT TYPE 3


(Homo sapiens)
PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka)
5 LEU A 641
VAL A 672
ILE A 634
ASP A 761
ILE A 760
None
1.42A 1gebA-3ihyA:
undetectable
1gebA-3ihyA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jtw DIHYDROFOLATE
REDUCTASE


(Pediococcus
pentosaceus)
PF01872
(RibD_C)
5 THR A  49
VAL A 115
ILE A 120
VAL A  79
ILE A  78
None
None
SO4  A 179 ( 4.9A)
None
None
1.19A 1gebA-3jtwA:
undetectable
1gebA-3jtwA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ob8 BETA-GALACTOSIDASE

(Kluyveromyces
lactis)
PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
5 THR A 666
LEU A 685
VAL A 691
VAL A 700
ILE A 680
None
1.28A 1gebA-3ob8A:
undetectable
1gebA-3ob8A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pzl AGMATINE
UREOHYDROLASE


(Thermoplasma
volcanium)
PF00491
(Arginase)
5 PHE A 268
VAL A 254
VAL A 271
ASP A 269
ILE A 270
None
1.43A 1gebA-3pzlA:
undetectable
1gebA-3pzlA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s5s MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY PROTEIN


(Sorangium
cellulosum)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
5 LEU A 199
VAL A 167
ILE A 179
VAL A 218
ILE A 192
None
1.39A 1gebA-3s5sA:
undetectable
1gebA-3s5sA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wgp VITAMIN D3 RECEPTOR

(Homo sapiens)
PF00104
(Hormone_recep)
5 THR A 362
LEU A 332
VAL A 331
ILE A 248
ILE A 134
None
1.31A 1gebA-3wgpA:
undetectable
1gebA-3wgpA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2p RETINOIC ACID
INDUCIBLE PROTEIN I


(Anas
platyrhynchos)
PF00270
(DEAD)
PF00271
(Helicase_C)
5 PHE A 369
LEU A 299
ILE A 327
VAL A 337
ILE A 341
None
1.02A 1gebA-4a2pA:
undetectable
1gebA-4a2pA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2p RETINOIC ACID
INDUCIBLE PROTEIN I


(Anas
platyrhynchos)
PF00270
(DEAD)
PF00271
(Helicase_C)
5 PHE A 369
LEU A 389
ILE A 353
VAL A 337
ILE A 341
None
1.33A 1gebA-4a2pA:
undetectable
1gebA-4a2pA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I


(Anas
platyrhynchos)
PF00270
(DEAD)
PF00271
(Helicase_C)
PF16739
(CARD_2)
5 PHE A 369
LEU A 389
ILE A 353
VAL A 337
ILE A 341
None
1.22A 1gebA-4a2qA:
undetectable
1gebA-4a2qA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2w RETINOIC ACID
INDUCIBLE PROTEIN I


(Anas
platyrhynchos)
PF00270
(DEAD)
PF00271
(Helicase_C)
PF16739
(CARD_2)
5 PHE A 369
LEU A 389
ILE A 353
VAL A 337
ILE A 341
None
1.28A 1gebA-4a2wA:
undetectable
1gebA-4a2wA:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bps FKBO

(Streptomyces
hygroscopicus)
no annotation 5 PHE A 123
TYR A 119
THR A 137
VAL A 225
ILE A 171
None
1.17A 1gebA-4bpsA:
undetectable
1gebA-4bpsA:
21.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4c9m CYTOCHROME P450

(Novosphingobium
aromaticivorans)
PF00067
(p450)
6 TYR A  98
THR A 103
LEU A 252
VAL A 303
ASP A 305
ILE A 403
None
GOL  A1419 (-3.8A)
HEM  A1418 (-4.0A)
GOL  A1419 (-3.9A)
HEM  A1418 (-2.7A)
None
0.61A 1gebA-4c9mA:
58.5
1gebA-4c9mA:
44.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d6v G PROTEIN BETA
SUBUNIT GIB2


(Cryptococcus
neoformans)
PF00400
(WD40)
5 THR A 187
LEU A 184
ILE A 129
VAL A 151
ASP A 171
None
0.92A 1gebA-4d6vA:
undetectable
1gebA-4d6vA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fuu LEUCINE
AMINOPEPTIDASE


(Bacteroides
thetaiotaomicron)
PF04389
(Peptidase_M28)
5 PHE A 218
LEU A 121
ILE A 288
VAL A 249
ILE A 245
None
1.34A 1gebA-4fuuA:
undetectable
1gebA-4fuuA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gk9 AGGLUTININ (BOA)

(Burkholderia
oklahomensis)
no annotation 5 PHE A 269
VAL A 241
ILE A 179
VAL A 177
ILE A 246
None
1.27A 1gebA-4gk9A:
undetectable
1gebA-4gk9A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j0q ELONGATION FACTOR
TU-A


(Pseudomonas
putida)
PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3)
PF03144
(GTP_EFTU_D2)
5 TYR A  70
VAL A 192
ILE A 171
VAL A 132
ILE A 103
None
1.13A 1gebA-4j0qA:
undetectable
1gebA-4j0qA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j3b M1 FAMILY
AMINOPEPTIDASE


(Plasmodium
falciparum)
PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C)
5 LEU A 307
VAL A 387
ILE A 469
VAL A 454
ILE A 313
None
1.34A 1gebA-4j3bA:
undetectable
1gebA-4j3bA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jn7 ENOLASE

(Agrobacterium
tumefaciens)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
5 VAL A 289
ILE A 278
VAL A 269
ASP A 265
ILE A 266
None
1.36A 1gebA-4jn7A:
undetectable
1gebA-4jn7A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kvs ALDEHYDE
DECARBONYLASE


(Prochlorococcus
marinus)
PF11266
(Ald_deCOase)
5 TYR A  30
LEU A  87
VAL A  89
VAL A  41
ILE A  37
None
None
None
6NA  A 301 ( 4.2A)
None
1.17A 1gebA-4kvsA:
undetectable
1gebA-4kvsA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l37 ARYLPHORIN

(Bombyx mori)
PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C)
5 PHE B 558
ILE B 551
VAL B 510
ASP B 538
ILE B 512
None
1.34A 1gebA-4l37B:
undetectable
1gebA-4l37B:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lun NONSENSE-MEDIATED
MRNA DECAY PROTEIN 2


(Saccharomyces
cerevisiae)
PF02854
(MIF4G)
5 PHE U  40
LEU U  57
ILE U  97
VAL U  76
ILE U  72
None
1.40A 1gebA-4lunU:
undetectable
1gebA-4lunU:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q1z PUTATIVE LIPOPROTEIN

(Bacteroides
thetaiotaomicron)
PF16215
(DUF4876)
5 PHE A 224
TYR A 256
THR A 258
ILE A 267
ILE A 197
None
1.35A 1gebA-4q1zA:
undetectable
1gebA-4q1zA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r3u 2-HYDROXYISOBUTYRYL-
COA MUTASE LARGE
SUBUNIT


(Aquincola
tertiaricarbonis)
PF01642
(MM_CoA_mutase)
5 PHE A 287
TYR A 309
VAL A 268
ILE A 226
ILE A 241
None
1.27A 1gebA-4r3uA:
undetectable
1gebA-4r3uA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rk6 GLUCOSE-RESISTANCE
AMYLASE REGULATOR


(Weissella
paramesenteroides)
PF13377
(Peripla_BP_3)
5 THR A  86
LEU A  93
VAL A  65
ILE A  78
ILE A 143
None
1.37A 1gebA-4rk6A:
undetectable
1gebA-4rk6A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4txd CSC2

(Thermofilum
pendens)
no annotation 5 THR A  85
LEU A 249
VAL A 264
ILE A 266
VAL A  39
None
1.00A 1gebA-4txdA:
undetectable
1gebA-4txdA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w8l ENDO-1,4-BETA-XYLANA
SE C


(Paenibacillus
barcinonensis)
PF00331
(Glyco_hydro_10)
5 VAL A 546
ILE A 509
VAL A 476
ASP A 529
ILE A 477
None
1.38A 1gebA-4w8lA:
undetectable
1gebA-4w8lA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x2d FIC FAMILY PROTEIN
PUTATIVE
FILAMENTATION
INDUCED BY CAMP
PROTEIN


(Clostridioides
difficile)
PF02661
(Fic)
5 PHE A 165
TYR A 110
LEU A 134
VAL A 176
ILE A 172
None
1.43A 1gebA-4x2dA:
undetectable
1gebA-4x2dA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xyb FORMATE
DEHYDROGENASE


(Granulicella
mallensis)
PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
5 LEU A 208
VAL A 207
ILE A 159
VAL A 251
ILE A 252
None
1.42A 1gebA-4xybA:
undetectable
1gebA-4xybA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y9v PARTICLE-ASSOCIATED
LYASE


(Acinetobacter
virus AP22)
no annotation 5 PHE A 194
LEU A 179
ILE A 164
VAL A 188
ILE A 192
None
1.34A 1gebA-4y9vA:
undetectable
1gebA-4y9vA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z5s ALDEHYDE
DECARBONYLASE


(Synechocystis
sp. PCC 6803)
PF11266
(Ald_deCOase)
5 TYR A  17
LEU A  74
VAL A  76
VAL A  28
ILE A  24
None
1.26A 1gebA-4z5sA:
undetectable
1gebA-4z5sA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z96 UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7


(Homo sapiens)
PF12436
(USP7_ICP0_bdg)
PF14533
(USP7_C2)
5 PHE A 903
LEU A1009
VAL A 992
ILE A 949
ILE A1005
None
1.42A 1gebA-4z96A:
undetectable
1gebA-4z96A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a31 ANAPHASE-PROMOTING
COMPLEX SUBUNIT 1


(Homo sapiens)
PF12859
(ANAPC1)
5 THR A 433
VAL A 490
ILE A 587
VAL A 595
ILE A 609
None
1.33A 1gebA-5a31A:
undetectable
1gebA-5a31A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a31 ANAPHASE-PROMOTING
COMPLEX SUBUNIT 1


(Homo sapiens)
PF12859
(ANAPC1)
5 TYR A 642
THR A 487
LEU A 499
VAL A 509
ILE A 607
None
1.32A 1gebA-5a31A:
undetectable
1gebA-5a31A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5by6 THYMIDYLATE SYNTHASE

(Trichinella
spiralis)
PF00303
(Thymidylat_synt)
5 PHE A 290
ILE A 234
VAL A 279
ASP A 289
ILE A 275
None
1.29A 1gebA-5by6A:
undetectable
1gebA-5by6A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d1r RV1816
TRANSCRIPTIONAL
REGULATOR


(Mycobacterium
tuberculosis)
PF00440
(TetR_N)
5 LEU A  66
VAL A  22
ILE A  42
VAL A  53
ILE A  17
None
1.40A 1gebA-5d1rA:
undetectable
1gebA-5d1rA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hvn 3-DEHYDROQUINATE
SYNTHASE


(Francisella
tularensis)
PF01761
(DHQ_synthase)
5 THR A  86
LEU A  38
VAL A  39
ILE A 107
ILE A  67
None
1.18A 1gebA-5hvnA:
undetectable
1gebA-5hvnA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i1w CRMK

(Actinoalloteichus
sp. WH1-2216-6)
PF01565
(FAD_binding_4)
PF08031
(BBE)
5 PHE A  34
TYR A  16
VAL A  28
VAL A  75
ILE A  78
None
1.40A 1gebA-5i1wA:
undetectable
1gebA-5i1wA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ipy FLAVIN-CONTAINING
MONOOXYGENASE


(Roseovarius
nubinhibens)
PF00743
(FMO-like)
5 PHE A 189
TYR A  67
ILE A 224
VAL A 202
ILE A 269
None
1.14A 1gebA-5ipyA:
undetectable
1gebA-5ipyA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k52 ALDEHYDE
DECARBONYLASE


(Limnothrix sp.
KNUA012)
PF11266
(Ald_deCOase)
5 TYR A  17
LEU A  74
VAL A  76
VAL A  28
ILE A  24
None
None
None
OCD  A 500 ( 4.6A)
OCD  A 500 (-4.6A)
1.20A 1gebA-5k52A:
undetectable
1gebA-5k52A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k53 ALDEHYDE
DEFORMYLATING
OXYGENASE


(Oscillatoria
sp.)
PF11266
(Ald_deCOase)
5 TYR A  17
LEU A  74
VAL A  76
VAL A  28
ILE A  24
None
None
None
STE  A 502 ( 4.8A)
STE  A 502 (-4.4A)
1.11A 1gebA-5k53A:
undetectable
1gebA-5k53A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lcw ANAPHASE-PROMOTING
COMPLEX SUBUNIT 1


(Homo sapiens)
PF12859
(ANAPC1)
5 THR A 433
VAL A 490
ILE A 587
VAL A 595
ILE A 609
None
1.27A 1gebA-5lcwA:
undetectable
1gebA-5lcwA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lcw ANAPHASE-PROMOTING
COMPLEX SUBUNIT 1


(Homo sapiens)
PF12859
(ANAPC1)
5 TYR A 642
THR A 487
LEU A 499
VAL A 509
ILE A 607
None
1.28A 1gebA-5lcwA:
undetectable
1gebA-5lcwA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mal LIPASE

(Streptomyces
rimosus)
PF13472
(Lipase_GDSL_2)
5 THR A 174
LEU A 120
VAL A 123
ILE A 127
VAL A 136
None
1.37A 1gebA-5malA:
undetectable
1gebA-5malA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u3c CTP SYNTHASE

(Escherichia
coli)
PF00117
(GATase)
PF06418
(CTP_synth_N)
5 LEU A 341
VAL A 333
VAL A 384
ASP A 388
ILE A 362
None
1.37A 1gebA-5u3cA:
undetectable
1gebA-5u3cA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u8e ARGININE KINASE

(Polybetes
pythagoricus)
PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN)
5 TYR A  75
THR A 269
LEU A 275
VAL A  65
ILE A  67
None
1.38A 1gebA-5u8eA:
undetectable
1gebA-5u8eA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uqi PHOSPHOSUGAR
ISOMERASE


(Escherichia
coli)
no annotation 5 PHE A  48
THR A  70
LEU A 172
VAL A 168
ILE A  95
None
1.42A 1gebA-5uqiA:
undetectable
1gebA-5uqiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ur0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE


(Naegleria
gruberi)
no annotation 5 PHE A   9
LEU A  58
VAL A  67
VAL A  74
ILE A  31
None
1.28A 1gebA-5ur0A:
undetectable
1gebA-5ur0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y37 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE


(Streptococcus
agalactiae)
no annotation 5 THR A 125
LEU A 328
ILE A  25
VAL A   9
ILE A  96
NAD  A 401 (-4.2A)
None
None
None
None
1.29A 1gebA-5y37A:
undetectable
1gebA-5y37A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z0c NEROL DEHYDROGENASE

(Persicaria
minor)
no annotation 5 PHE A 358
LEU A  70
ILE A  75
ASP A 141
ILE A 354
None
1.36A 1gebA-5z0cA:
undetectable
1gebA-5z0cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c0b TOXIN B

(Clostridioides
difficile)
no annotation 5 TYR A1724
LEU A1780
VAL A1731
ILE A1704
ILE A1674
None
1.30A 1gebA-6c0bA:
undetectable
1gebA-6c0bA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cqo SINGLE-STRANDED
DNA-BINDING PROTEIN
RIM1, MITOCHONDRIAL


(Saccharomyces
cerevisiae)
no annotation 5 LEU A  44
VAL A  65
ILE A 113
VAL A  84
ILE A  48
None
1.36A 1gebA-6cqoA:
undetectable
1gebA-6cqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eu6 AMMONIUM TRANSPORTER

(Candidatus
Kuenenia
stuttgartiensis)
no annotation 5 PHE A  34
TYR A  30
THR A 213
LEU A 274
VAL A 325
None
1.36A 1gebA-6eu6A:
undetectable
1gebA-6eu6A:
undetectable