SIMILAR PATTERNS OF AMINO ACIDS FOR 1FDU_D_ESTD352_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1a27 17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE

(Homo sapiens) 		PF00106
(adh_short) 		6 SER A 142
VAL A 143
GLY A 144
LEU A 149
TYR A 155
GLU A 282
 EST  A 350 (-3.0A)
EST  A 350 (-4.5A)
EST  A 350 (-3.4A)
EST  A 350 (-4.4A)
EST  A 350 (-4.2A)
EST  A 350 ( 4.6A)
 0.65A 1fduD-1a27A:
44.8		 1fduD-1a27A:
99.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b41 ACETYLCHOLINESTERASE

(Homo sapiens) 		PF00135
(COesterase) 		4 VAL A 365
GLY A 366
LEU A 398
GLU A 358
 None
 0.94A 1fduD-1b41A:
undetectable		 1fduD-1b41A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b8k PROTEIN
(NEUROTROPHIN-3)

(Homo sapiens) 		PF00243
(NGF) 		4 VAL A  97
GLY A  98
LEU A  89
GLU A  40
 None
 0.97A 1fduD-1b8kA:
undetectable		 1fduD-1b8kA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c3r HDLP (HISTONE
DEACETYLASE-LIKE
PROTEIN)

(Aquifex
aeolicus) 		PF00850
(Hist_deacetyl) 		4 SER A  49
GLY A   8
LEU A  32
TYR A  12
 None
 1.01A 1fduD-1c3rA:
4.5		 1fduD-1c3rA:
24.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1fdw 17-BETA-HYDROXYSTERO
ID DEHYDROGENASE

(Homo sapiens) 		PF00106
(adh_short) 		4 SER A 142
VAL A 143
GLY A 144
GLU A 282
 EST  A 350 (-4.3A)
EST  A 350 (-4.8A)
EST  A 350 ( 4.5A)
None
 0.61A 1fduD-1fdwA:
41.0		 1fduD-1fdwA:
99.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1fdw 17-BETA-HYDROXYSTERO
ID DEHYDROGENASE

(Homo sapiens) 		PF00106
(adh_short) 		5 SER A 142
VAL A 143
GLY A 144
LEU A 149
TYR A 155
 EST  A 350 (-4.3A)
EST  A 350 (-4.8A)
EST  A 350 ( 4.5A)
EST  A 350 (-4.6A)
None
 0.48A 1fduD-1fdwA:
41.0		 1fduD-1fdwA:
99.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h0h FORMATE
DEHYDROGENASE
SUBUNIT ALPHA

(Desulfovibrio
gigas) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		4 SER A 125
VAL A 126
GLY A 127
TYR A 139
 None
 0.97A 1fduD-1h0hA:
2.9		 1fduD-1h0hA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kz7 GUANINE NUCLEOTIDE
EXCHANGE FACTOR DBS

(Mus musculus) 		PF00169
(PH)
PF00621
(RhoGEF) 		4 VAL A 711
GLY A 712
LEU A 795
GLU A 781
 None
 1.02A 1fduD-1kz7A:
undetectable		 1fduD-1kz7A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A

(Haemophilus
influenzae) 		PF06026
(Rib_5-P_isom_A) 		4 VAL A 144
GLY A 145
LEU A 170
GLU A 135
 None
 0.98A 1fduD-1m0sA:
undetectable		 1fduD-1m0sA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1opk PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1

(Mus musculus) 		PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr) 		4 VAL A 323
GLY A 322
LEU A 320
GLU A 311
 None
 1.03A 1fduD-1opkA:
undetectable		 1fduD-1opkA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qs1 ADP-RIBOSYLTRANSFERA
SE

(Bacillus cereus) 		PF03496
(ADPrib_exo_Tox) 		4 VAL A 223
GLY A 222
LEU A 138
GLU A  64
 None
 0.89A 1fduD-1qs1A:
undetectable		 1fduD-1qs1A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t34 ATRIAL NATRIURETIC
PEPTIDE RECEPTOR A

(Rattus
norvegicus) 		PF01094
(ANF_receptor) 		4 VAL A  93
GLY A  94
LEU A 104
TYR A 120
 None
 0.76A 1fduD-1t34A:
6.0		 1fduD-1t34A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ta3 XYLANASE INHIBITOR
PROTEIN I

(Triticum
aestivum) 		PF00704
(Glyco_hydro_18) 		4 VAL A 123
GLY A 122
LEU A 156
GLU A 142
 None
 1.01A 1fduD-1ta3A:
2.3		 1fduD-1ta3A:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ydo HMG-COA LYASE

(Bacillus
subtilis) 		PF00682
(HMGL-like) 		4 SER A 233
GLY A 236
LEU A 288
GLU A 282
 None
 1.01A 1fduD-1ydoA:
2.3		 1fduD-1ydoA:
25.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yts YERSINIA PROTEIN
TYROSINE PHOSPHATASE

(Yersinia
enterocolitica) 		PF00102
(Y_phosphatase) 		4 VAL A 251
GLY A 252
LEU A 427
GLU A 430
 None
 1.02A 1fduD-1ytsA:
undetectable		 1fduD-1ytsA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bmb FOLIC ACID SYNTHESIS
PROTEIN FOL1

(Saccharomyces
cerevisiae) 		PF00809
(Pterin_bind)
PF01288
(HPPK) 		4 VAL A 731
GLY A 732
LEU A 777
TYR A 780
 None
 0.91A 1fduD-2bmbA:
2.4		 1fduD-2bmbA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dlc TYROSYL-TRNA
SYNTHETASE,
CYTOPLASMIC

(Saccharomyces
cerevisiae) 		PF00579
(tRNA-synt_1b) 		4 SER X 126
GLY X 124
LEU X  76
GLU X 178
 None
None
YMP  X 601 (-4.8A)
None
 0.91A 1fduD-2dlcX:
undetectable		 1fduD-2dlcX:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2edo CD48 ANTIGEN

(Homo sapiens) 		PF07686
(V-set) 		4 SER A  72
LEU A  68
TYR A  76
GLU A  49
 None
 1.03A 1fduD-2edoA:
undetectable		 1fduD-2edoA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f8q ALKALINE
THERMOSTABLE
ENDOXYLANASE

(Bacillus sp.
NG-27) 		PF00331
(Glyco_hydro_10) 		4 SER A 164
VAL A 165
LEU A 122
TYR A 174
 None
 0.92A 1fduD-2f8qA:
undetectable		 1fduD-2f8qA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hqm GLUTATHIONE
REDUCTASE

(Saccharomyces
cerevisiae) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 VAL A 215
GLY A 214
TYR A 248
GLU A 288
 None
 1.01A 1fduD-2hqmA:
5.8		 1fduD-2hqmA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hz0 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 VAL A 304
GLY A 303
LEU A 301
GLU A 292
 None
 0.94A 1fduD-2hz0A:
undetectable		 1fduD-2hz0A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2icw T-CELL RECEPTOR BETA
CHAIN V

(Mus musculus) 		PF07686
(V-set) 		4 GLY J  58
LEU J  45
TYR J  48
GLU J  42
 None
 0.96A 1fduD-2icwJ:
undetectable		 1fduD-2icwJ:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j4l URIDYLATE KINASE

(Sulfolobus
solfataricus) 		PF00696
(AA_kinase) 		4 SER A 221
VAL A 201
GLY A 143
GLU A 182
 None
 1.04A 1fduD-2j4lA:
undetectable		 1fduD-2j4lA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mzj NUCLEOLAR PROTEIN 6

(Saccharomyces
cerevisiae) 		PF00076
(RRM_1) 		4 VAL A   8
GLY A   9
LEU A  11
GLU A  19
 None
 0.92A 1fduD-2mzjA:
undetectable		 1fduD-2mzjA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oa2 BH2720 PROTEIN

(Bacillus
halodurans) 		PF07883
(Cupin_2) 		4 VAL A 239
GLY A 222
LEU A 263
GLU A 218
 None
 0.86A 1fduD-2oa2A:
undetectable		 1fduD-2oa2A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pcn S-ADENOSYLMETHIONINE
:2-DEMETHYLMENAQUINO
NE METHYLTRANSFERASE

(Geobacillus
kaustophilus) 		PF03737
(RraA-like) 		4 VAL A  90
GLY A  89
LEU A  87
GLU A  53
 None
 0.94A 1fduD-2pcnA:
undetectable		 1fduD-2pcnA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q2r GLUCOKINASE 1,
PUTATIVE

(Trypanosoma
cruzi) 		PF02685
(Glucokinase) 		4 VAL A 289
GLY A 290
LEU A 179
TYR A 345
 None
 1.04A 1fduD-2q2rA:
undetectable		 1fduD-2q2rA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qj8 MLR6093 PROTEIN

(Mesorhizobium
japonicum) 		PF04952
(AstE_AspA) 		4 VAL A 223
GLY A 222
LEU A 175
GLU A 205
 None
 0.69A 1fduD-2qj8A:
undetectable		 1fduD-2qj8A:
26.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r4b RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 VAL A 786
GLY A 785
LEU A 783
GLU A 768
 None
None
GW7  A   1 (-3.9A)
None
 0.93A 1fduD-2r4bA:
undetectable		 1fduD-2r4bA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xiv HYPOTHETICAL
INVASION PROTEIN

(Mycobacterium
tuberculosis) 		PF00877
(NLPC_P60) 		4 SER A 352
GLY A 350
LEU A 386
TYR A 389
 None
 0.92A 1fduD-2xivA:
undetectable		 1fduD-2xivA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ywd GLUTAMINE
AMIDOTRANSFERASE
SUBUNIT PDXT

(Thermus
thermophilus) 		PF01174
(SNO) 		4 VAL A  45
GLY A  79
LEU A  87
GLU A  63
 None
 1.04A 1fduD-2ywdA:
3.3		 1fduD-2ywdA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z0q RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 3

(Mus musculus) 		PF00621
(RhoGEF) 		4 VAL A  87
GLY A  88
LEU A 177
GLU A 162
 None
 0.98A 1fduD-2z0qA:
undetectable		 1fduD-2z0qA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ab4 ASPARTOKINASE

(Corynebacterium
glutamicum) 		PF00696
(AA_kinase)
PF01842
(ACT)
PF13840
(ACT_7) 		4 VAL A 258
GLY A 257
LEU A 407
GLU A 403
 None
 1.01A 1fduD-3ab4A:
2.2		 1fduD-3ab4A:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cf4 ACETYL-COA
DECARBOXYLASE/SYNTHA
SE ALPHA SUBUNIT

(Methanosarcina
barkeri) 		PF03063
(Prismane) 		4 VAL A 298
GLY A 275
LEU A 283
GLU A 288
 None
None
None
GOL  A 826 (-3.7A)
 0.95A 1fduD-3cf4A:
6.8		 1fduD-3cf4A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3clh 3-DEHYDROQUINATE
SYNTHASE

(Helicobacter
pylori) 		PF01761
(DHQ_synthase) 		4 VAL A 321
GLY A 320
LEU A 269
GLU A 275
 None
 0.84A 1fduD-3clhA:
undetectable		 1fduD-3clhA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d34 SPONDIN-2

(Homo sapiens) 		PF06468
(Spond_N) 		4 VAL A 139
GLY A 138
LEU A 158
TYR A 161
 None
 1.04A 1fduD-3d34A:
undetectable		 1fduD-3d34A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE

(Bacillus
halodurans) 		PF01266
(DAO)
PF16901
(DAO_C) 		4 VAL A 186
GLY A  45
LEU A  19
GLU A  16
 None
 0.88A 1fduD-3da1A:
3.4		 1fduD-3da1A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f8k PROTEIN
ACETYLTRANSFERASE

(Sulfolobus
solfataricus) 		PF00583
(Acetyltransf_1) 		4 VAL A 110
GLY A  75
LEU A  71
GLU A 100
 None
 0.90A 1fduD-3f8kA:
undetectable		 1fduD-3f8kA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g23 LD-CARBOXYPEPTIDASE
A

(Novosphingobium
aromaticivorans) 		PF02016
(Peptidase_S66) 		4 SER A 237
VAL A 238
LEU A 221
GLU A 191
 None
 0.58A 1fduD-3g23A:
5.1		 1fduD-3g23A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3grf ORNITHINE
CARBAMOYLTRANSFERASE

(Giardia
intestinalis) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 SER A 169
GLY A 167
LEU A 259
GLU A 253
 None
 1.02A 1fduD-3grfA:
3.6		 1fduD-3grfA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gt2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Mycobacterium
avium) 		PF00877
(NLPC_P60) 		4 SER A  88
GLY A  86
LEU A 122
TYR A 125
 None
 0.95A 1fduD-3gt2A:
undetectable		 1fduD-3gt2A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hdj PROBABLE ORNITHINE
CYCLODEAMINASE

(Bordetella
pertussis) 		PF02423
(OCD_Mu_crystall) 		4 SER A 283
VAL A 284
GLY A 285
GLU A 236
 GOL  A 316 (-4.9A)
GOL  A 316 (-4.0A)
None
None
 1.04A 1fduD-3hdjA:
4.5		 1fduD-3hdjA:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i2n WD REPEAT-CONTAINING
PROTEIN 92

(Homo sapiens) 		PF00400
(WD40) 		4 SER A 231
VAL A 212
GLY A 211
GLU A 205
 None
 0.95A 1fduD-3i2nA:
undetectable		 1fduD-3i2nA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l77 SHORT-CHAIN ALCOHOL
DEHYDROGENASE

(Thermococcus
sibiricus) 		PF00106
(adh_short) 		4 SER A 152
GLY A 149
LEU A  98
GLU A 101
 None
 0.97A 1fduD-3l77A:
27.0		 1fduD-3l77A:
27.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lx2 DNA POLYMERASE
SLIDING CLAMP 2

(Thermococcus
kodakarensis) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 VAL A 101
GLY A 102
LEU A 103
GLU A  14
 None
 0.83A 1fduD-3lx2A:
undetectable		 1fduD-3lx2A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m8y PHOSPHOPENTOMUTASE

(Bacillus cereus) 		PF01676
(Metalloenzyme) 		4 SER A 157
GLY A 192
LEU A 217
GLU A 182
 None
 0.97A 1fduD-3m8yA:
undetectable		 1fduD-3m8yA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3op0 SIGNAL TRANSDUCTION
PROTEIN CBL-C

(Homo sapiens) 		PF02262
(Cbl_N)
PF02761
(Cbl_N2)
PF02762
(Cbl_N3) 		4 SER A  61
VAL A  58
GLY A 142
GLU A 134
 None
None
None
NA  A   2 ( 4.9A)
 0.89A 1fduD-3op0A:
undetectable		 1fduD-3op0A:
25.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pay PUTATIVE ADHESIN

(Bacteroides
ovatus) 		PF08842
(Mfa2) 		4 VAL A  56
GLY A 101
LEU A 169
GLU A  36
 None
 0.83A 1fduD-3payA:
undetectable		 1fduD-3payA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qc3 D-RIBULOSE-5-PHOSPHA
TE-3-EPIMERASE

(Homo sapiens) 		PF00834
(Ribul_P_3_epim) 		4 SER A 196
VAL A 178
GLY A 179
GLU A 188
 None
 0.94A 1fduD-3qc3A:
undetectable		 1fduD-3qc3A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t61 GLUCONOKINASE

(Sinorhizobium
meliloti) 		PF01202
(SKI) 		4 SER A  90
VAL A  89
LEU A  50
GLU A  79
 None
 1.03A 1fduD-3t61A:
4.2		 1fduD-3t61A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ulk KETOL-ACID
REDUCTOISOMERASE

(Escherichia
coli) 		PF01450
(IlvC)
PF07991
(IlvN) 		4 GLY A  44
LEU A  67
TYR A  65
GLU A  74
 GLY  A  44 (-0.0A)
LEU  A  67 ( 0.6A)
TYR  A  65 ( 1.3A)
GLU  A  74 (-0.6A)
 1.04A 1fduD-3ulkA:
6.5		 1fduD-3ulkA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uve CARVEOL
DEHYDROGENASE
((+)-TRANS-CARVEOL
DEHYDROGENASE)

(Mycobacterium
avium) 		PF13561
(adh_short_C2) 		4 SER A 161
VAL A 162
GLY A 163
TYR A 174
 NAD  A 300 (-3.4A)
None
None
NAD  A 300 (-4.7A)
 0.64A 1fduD-3uveA:
26.2		 1fduD-3uveA:
26.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v4d AMINOACRYLATE
PERACID REDUCTASE
RUTC

(Escherichia
coli) 		PF01042
(Ribonuc_L-PSP) 		4 SER A  31
VAL A  30
GLY A  21
GLU A  64
 None
 0.95A 1fduD-3v4dA:
undetectable		 1fduD-3v4dA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vkw REPLICASE LARGE
SUBUNIT

(Tobacco mosaic
virus) 		PF01443
(Viral_helicase1) 		4 SER A1005
GLY A1002
LEU A1055
GLU A1026
 None
 0.80A 1fduD-3vkwA:
undetectable		 1fduD-3vkwA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wbb DIAMINOPIMELATE
DEHYDROGENASE

(Symbiobacterium
thermophilum) 		PF01408
(GFO_IDH_MocA)
PF16654
(DAPDH_C) 		4 VAL A  33
GLY A  32
LEU A  30
GLU A  20
 None
 0.62A 1fduD-3wbbA:
8.5		 1fduD-3wbbA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wso F-BOX ONLY PROTEIN
44

(Homo sapiens) 		PF04300
(FBA)
PF12937
(F-box-like) 		4 SER A 172
VAL A 230
GLY A 229
LEU A 134
 None
 0.92A 1fduD-3wsoA:
undetectable		 1fduD-3wsoA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x1l CMR6

(Archaeoglobus
fulgidus) 		PF03787
(RAMPs) 		4 SER H 223
VAL H 224
GLY H 225
GLU H 206
 None
 0.47A 1fduD-3x1lH:
undetectable		 1fduD-3x1lH:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE

(Trichoderma
reesei) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 SER A 482
VAL A 483
GLY A 484
GLU A 166
 None
 0.73A 1fduD-3zz1A:
3.9		 1fduD-3zz1A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2p RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 SER A 413
VAL A 414
GLY A 415
GLU A 427
 None
 1.00A 1fduD-4a2pA:
2.4		 1fduD-4a2pA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4anj UNCONVENTIONAL
MYOSIN-VI, GREEN
FLUORESCENT PROTEIN

(Aequorea
victoria;
Sus scrofa) 		PF00063
(Myosin_head)
PF01353
(GFP) 		4 SER A 642
VAL A 643
GLY A 644
GLU A 231
 None
 0.89A 1fduD-4anjA:
undetectable		 1fduD-4anjA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4by9 FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE

(Pyrococcus
furiosus) 		PF01269
(Fibrillarin) 		4 VAL E 224
GLY E 174
LEU E 160
GLU E 199
 None
 0.88A 1fduD-4by9E:
7.1		 1fduD-4by9E:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bz2 FAB 2D73 HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 VAL H  48
GLY H  49
LEU H  70
GLU H  82
 None
 1.02A 1fduD-4bz2H:
undetectable		 1fduD-4bz2H:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c2l ENDO-XYLOGALACTURONA
N HYDROLASE A

(Aspergillus
tubingensis) 		PF00295
(Glyco_hydro_28) 		4 SER A 254
VAL A 255
GLY A 256
LEU A 258
 None
None
SO4  A1407 (-4.8A)
None
 0.94A 1fduD-4c2lA:
undetectable		 1fduD-4c2lA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ep5 CROSSOVER JUNCTION
ENDODEOXYRIBONUCLEAS
E RUVC

(Thermus
thermophilus) 		PF02075
(RuvC) 		4 VAL A  17
GLY A  16
LEU A  15
GLU A  57
 None
 0.84A 1fduD-4ep5A:
2.5		 1fduD-4ep5A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f4w DNA POLYMERASE IV

(Sulfolobus
acidocaldarius;
Sulfolobus
solfataricus) 		PF00817
(IMS)
PF11798
(IMS_HHH) 		4 VAL A 166
GLY A 165
LEU A 164
GLU A 124
 None
 1.01A 1fduD-4f4wA:
undetectable		 1fduD-4f4wA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ftf ALTERNATE SECRETIN
PATHWAY SUBUNIT S
(VC395_1821, VC1703)

(Vibrio cholerae) 		PF16549
(T2SSS_2) 		4 VAL A  85
GLY A  86
LEU A  12
GLU A   7
 None
 1.01A 1fduD-4ftfA:
undetectable		 1fduD-4ftfA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ha6 PYRIDOXINE 4-OXIDASE

(Mesorhizobium
loti) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 GLY A 425
LEU A 430
TYR A 316
GLU A 175
 None
 0.99A 1fduD-4ha6A:
4.2		 1fduD-4ha6A:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hdj OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMB

(Pseudomonas
aeruginosa) 		PF13360
(PQQ_2) 		4 VAL A 111
GLY A 101
LEU A  60
GLU A  75
 None
 0.88A 1fduD-4hdjA:
undetectable		 1fduD-4hdjA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iig BETA-GLUCOSIDASE 1

(Aspergillus
aculeatus) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 SER A 550
VAL A 551
GLY A 552
GLU A 197
 None
 0.89A 1fduD-4iigA:
4.2		 1fduD-4iigA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jxb INVASION-ASSOCIATED
PROTEIN

(Mycobacterium
tuberculosis) 		PF00877
(NLPC_P60) 		4 SER A  52
GLY A  50
LEU A  86
TYR A  89
 None
 0.93A 1fduD-4jxbA:
undetectable		 1fduD-4jxbA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kjd INTESTINAL-TYPE
ALKALINE PHOSPHATASE
1

(Rattus
norvegicus) 		PF00245
(Alk_phosphatase) 		4 VAL A 247
GLY A 267
LEU A 200
GLU A 290
 None
 1.04A 1fduD-4kjdA:
undetectable		 1fduD-4kjdA:
26.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kma GM14141P

(Drosophila
melanogaster) 		PF05076
(SUFU)
PF12470
(SUFU_C) 		4 VAL A 265
GLY A 264
LEU A 262
GLU A 205
 None
 1.00A 1fduD-4kmaA:
undetectable		 1fduD-4kmaA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mea PREDICTED PROTEIN

(Acinetobacter
nosocomialis) 		PF00561
(Abhydrolase_1) 		4 SER A 342
VAL A 339
GLY A 338
GLU A 333
 None
 0.91A 1fduD-4meaA:
4.8		 1fduD-4meaA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nen INTEGRIN BETA-2

(Homo sapiens) 		PF00362
(Integrin_beta)
PF07965
(Integrin_B_tail)
PF17205
(PSI_integrin) 		4 SER B 281
VAL B 282
GLY B 283
GLU B 313
 None
 0.70A 1fduD-4nenB:
4.9		 1fduD-4nenB:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q4g PEPTIDOGLYCAN
ENDOPEPTIDASE RIPA

(Mycobacterium
tuberculosis) 		PF00877
(NLPC_P60) 		4 SER X1090
GLY X1088
LEU X1124
TYR X1127
 None
 0.94A 1fduD-4q4gX:
undetectable		 1fduD-4q4gX:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qmd ENVOPLAKIN

(Homo sapiens) 		PF00681
(Plectin) 		4 SER A1916
VAL A1917
GLY A1918
LEU A1935
 None
 1.01A 1fduD-4qmdA:
undetectable		 1fduD-4qmdA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4twl DIOSCORIN 5

(Dioscorea
japonica) 		PF00194
(Carb_anhydrase) 		4 SER A  35
GLY A 180
TYR A 178
GLU A 118
 None
 0.90A 1fduD-4twlA:
undetectable		 1fduD-4twlA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uzy FLAGELLAR ASSOCIATED
PROTEIN

(Chlamydomonas
reinhardtii) 		PF12895
(ANAPC3)
PF13174
(TPR_6) 		4 SER A 227
VAL A 228
GLY A 229
GLU A 236
 None
 0.98A 1fduD-4uzyA:
undetectable		 1fduD-4uzyA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xey TYROSINE-PROTEIN
KINASE ABL1

(Homo sapiens) 		no annotation 4 VAL B 323
GLY B 322
LEU B 320
GLU B 311
 None
 1.03A 1fduD-4xeyB:
undetectable		 1fduD-4xeyB:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e3c DIPEPTIDYL PEPTIDASE
3

(Homo sapiens) 		PF03571
(Peptidase_M49) 		4 VAL A  99
GLY A 104
LEU A  49
GLU A 712
 None
 0.90A 1fduD-5e3cA:
undetectable		 1fduD-5e3cA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ej2 CARVEOL
DEHYDROGENASE

(Mycobacterium
avium) 		PF13561
(adh_short_C2) 		4 SER A 165
VAL A 166
GLY A 167
TYR A 178
 NAD  A 300 (-3.5A)
None
None
NAD  A 300 (-4.8A)
 0.65A 1fduD-5ej2A:
26.5		 1fduD-5ej2A:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ewq AMIDASE

(Bacillus
anthracis) 		PF01425
(Amidase) 		4 VAL A 508
GLY A 509
LEU A 463
GLU A 458
 None
 1.00A 1fduD-5ewqA:
undetectable		 1fduD-5ewqA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fji BETA-GLUCOSIDASE

(Aspergillus
fumigatus) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 SER A 551
VAL A 552
GLY A 553
GLU A 198
 None
 0.83A 1fduD-5fjiA:
3.2		 1fduD-5fjiA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fjj BETA-GLUCOSIDASE

(Aspergillus
oryzae) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 SER A 551
VAL A 552
GLY A 553
GLU A 198
 None
 0.91A 1fduD-5fjjA:
5.1		 1fduD-5fjjA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5id6 CPF1

(Lachnospiraceae
bacterium
ND2006) 		no annotation 4 SER A 462
VAL A 463
LEU A 308
GLU A 313
 None
 0.96A 1fduD-5id6A:
undetectable		 1fduD-5id6A:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5itw DIHYDROANTICAPSIN
7-DEHYDROGENASE

(Bacillus
subtilis) 		PF13561
(adh_short_C2) 		4 SER A 141
VAL A 142
GLY A 143
TYR A 154
 None
 0.57A 1fduD-5itwA:
27.7		 1fduD-5itwA:
27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j9h ENVELOPMENT
POLYPROTEIN

(Puumala
orthohantavirus) 		PF01561
(Hanta_G2) 		4 SER A 799
VAL A 800
GLY A 801
LEU A 857
 None
 0.78A 1fduD-5j9hA:
undetectable		 1fduD-5j9hA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jow NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43A

(Bacteroides
ovatus) 		PF04616
(Glyco_hydro_43) 		4 VAL A 427
GLY A 428
LEU A 415
GLU A 452
 None
 0.98A 1fduD-5jowA:
undetectable		 1fduD-5jowA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kha GLUTAMINE-DEPENDENT
NAD+ SYNTHETASE

(Acinetobacter
baumannii) 		PF00795
(CN_hydrolase)
PF02540
(NAD_synthase) 		4 SER A  12
VAL A 204
GLY A 205
GLU A 262
 None
 0.99A 1fduD-5khaA:
3.0		 1fduD-5khaA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nju GENOME POLYPROTEIN

(Zika virus) 		no annotation 4 SER A 232
VAL A 233
LEU A 195
GLU A 158
 None
 1.01A 1fduD-5njuA:
5.9		 1fduD-5njuA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5npu ANC27

(synthetic
construct) 		no annotation 4 VAL A   5
GLY A   6
LEU A  32
GLU A 165
 None
 1.03A 1fduD-5npuA:
2.4		 1fduD-5npuA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tjj TRANSCRIPTIONAL
REGULATOR, ICLR
FAMILY

(Alicyclobacillus
acidocaldarius) 		PF01614
(IclR)
PF09339
(HTH_IclR) 		4 SER A  56
VAL A  55
GLY A  67
LEU A  70
 None
 1.01A 1fduD-5tjjA:
undetectable		 1fduD-5tjjA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u4n FRUCTOSE-1

(Neisseria
gonorrhoeae) 		PF01116
(F_bP_aldolase) 		4 VAL A 194
GLY A 195
LEU A 212
GLU A 265
 None
 0.99A 1fduD-5u4nA:
undetectable		 1fduD-5u4nA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u6b TYROSINE-PROTEIN
KINASE RECEPTOR UFO

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 VAL A 603
GLY A 602
LEU A 600
GLU A 585
 None
 1.00A 1fduD-5u6bA:
undetectable		 1fduD-5u6bA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ulm MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE 5

(Homo sapiens) 		PF13281
(DUF4071) 		4 VAL A 478
GLY A 479
TYR A 510
GLU A 499
 None
 1.01A 1fduD-5ulmA:
undetectable		 1fduD-5ulmA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vip MDCD
MDCE

(Pseudomonas
aeruginosa) 		PF01039
(Carboxyl_trans)
PF06833
(MdcE) 		4 SER B 164
GLY B 162
LEU A 146
GLU B 135
 None
 1.03A 1fduD-5vipB:
2.8		 1fduD-5vipB:
25.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wix P-47 PROTEIN

(Clostridium
botulinum) 		no annotation 4 VAL A 362
GLY A 363
LEU A 315
GLU A 281
 None
 0.97A 1fduD-5wixA:
undetectable		 1fduD-5wixA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6anv ANTI-CRISPR PROTEIN
ACRF1 FUSED WITH
C-TERMINAL MBP TAG

(Escherichia
coli;
Pseudomonas
phage JBD30) 		no annotation 4 SER A  38
VAL A  39
GLY A  40
GLU A  66
 None
None
MES  A 502 (-3.4A)
None
 0.86A 1fduD-6anvA:
undetectable		 1fduD-6anvA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b8s DIHYDROOROTATE
DEHYDROGENASE
(QUINONE)

(Helicobacter
pylori) 		no annotation 4 SER A 131
GLY A 128
LEU A  92
GLU A  88
 None
 0.99A 1fduD-6b8sA:
undetectable		 1fduD-6b8sA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cip PYRUVATE-FERREDOXIN
OXIDOREDUCTASE

(Moorella
thermoacetica) 		no annotation 4 VAL A 295
GLY A 296
TYR A 261
GLU A 290
 None
 0.84A 1fduD-6cipA:
2.4		 1fduD-6cipA:
14.37