SIMILAR PATTERNS OF AMINO ACIDS FOR 1FBM_B_RTLB951_3

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a5c FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE

(Plasmodium
falciparum) 		PF00274
(Glycolytic) 		4 THR A 212
LEU A 216
VAL A 219
LEU A 223
 None
 0.64A 1fbmE-1a5cA:
undetectable		 1fbmE-1a5cA:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bct BACTERIORHODOPSIN

(Halobacterium
salinarum) 		PF01036
(Bac_rhodopsin) 		4 THR A 170
LEU A 174
VAL A 177
LEU A 181
 None
 0.85A 1fbmE-1bctA:
1.7		 1fbmE-1bctA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1brr PROTEIN
(BACTERIORHODOPSIN)

(Halobacterium
salinarum) 		PF01036
(Bac_rhodopsin) 		4 THR A 170
LEU A 174
VAL A 177
LEU A 181
 None
 0.75A 1fbmE-1brrA:
0.0		 1fbmE-1brrA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cby DELTA-ENDOTOXIN CYTB

(Bacillus
thuringiensis) 		PF01338
(Bac_thur_toxin) 		4 THR A  95
LEU A 220
LEU A  60
GLN A  56
 None
 0.90A 1fbmE-1cbyA:
undetectable		 1fbmE-1cbyA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ehk BA3-TYPE
CYTOCHROME-C OXIDASE

(Thermus
thermophilus) 		PF00115
(COX1) 		4 LEU A  75
VAL A  79
LEU A  83
GLN A  86
 None
 0.69A 1fbmE-1ehkA:
0.0		 1fbmE-1ehkA:
5.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE

(Drosophila
melanogaster) 		PF00274
(Glycolytic) 		4 THR A 205
LEU A 209
VAL A 212
LEU A 216
 None
 0.48A 1fbmE-1fbaA:
undetectable		 1fbmE-1fbaA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fdj FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE

(Oryctolagus
cuniculus) 		PF00274
(Glycolytic) 		4 THR A1205
LEU A1209
VAL A1212
LEU A1216
 None
 0.49A 1fbmE-1fdjA:
undetectable		 1fbmE-1fdjA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1he9 EXOENZYME S

(Pseudomonas
aeruginosa) 		PF03545
(YopE) 		5 THR A 207
LEU A 210
VAL A 213
LEU A 171
GLN A 167
 None
 1.46A 1fbmE-1he9A:
undetectable		 1fbmE-1he9A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jbk CLPB PROTEIN

(Escherichia
coli) 		PF00004
(AAA) 		4 LEU A 259
VAL A 262
LEU A 266
GLN A 269
 None
 0.59A 1fbmE-1jbkA:
undetectable		 1fbmE-1jbkA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lox 15-LIPOXYGENASE

(Oryctolagus
cuniculus) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		4 LEU A  39
VAL A  22
LEU A  65
GLN A 107
 None
 0.78A 1fbmE-1loxA:
undetectable		 1fbmE-1loxA:
6.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lpe APOLIPOPROTEIN E3

(Homo sapiens) 		PF01442
(Apolipoprotein) 		4 THR A  67
LEU A  71
LEU A  78
GLN A  81
 None
 0.69A 1fbmE-1lpeA:
undetectable		 1fbmE-1lpeA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ne7 GLUCOSAMINE-6-PHOSPH
ATE ISOMERASE

(Homo sapiens) 		PF01182
(Glucosamine_iso) 		4 THR A  68
LEU A  39
VAL A 135
LEU A 202
 None
 0.77A 1fbmE-1ne7A:
undetectable		 1fbmE-1ne7A:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nks ADENYLATE KINASE

(Sulfolobus
acidocaldarius) 		PF13207
(AAA_17) 		4 LEU A  18
VAL A  21
LEU A  25
GLN A  28
 None
 0.87A 1fbmE-1nksA:
undetectable		 1fbmE-1nksA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1org PHEROMONE BINDING
PROTEIN

(Rhyparobia
maderae) 		PF01395
(PBP_GOBP) 		4 THR A  63
LEU A  67
VAL A  70
LEU A  74
 None
 0.91A 1fbmE-1orgA:
undetectable		 1fbmE-1orgA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6a GENOME POLYPROTEIN

(Dengue virus) 		PF01728
(FtsJ) 		4 THR A 161
LEU A 165
VAL A 168
LEU A 172
 None
 0.68A 1fbmE-1r6aA:
undetectable		 1fbmE-1r6aA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6a GENOME POLYPROTEIN

(Dengue virus) 		PF01728
(FtsJ) 		5 THR A 176
LEU A 143
VAL A  78
LEU A 103
GLN A 127
 None
 0.92A 1fbmE-1r6aA:
undetectable		 1fbmE-1r6aA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1raj GENOME POLYPROTEIN

(Enterovirus C) 		PF00680
(RdRP_1) 		4 LEU A 253
VAL A 252
LEU A  85
GLN A  84
 None
 0.90A 1fbmE-1rajA:
undetectable		 1fbmE-1rajA:
7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sr2 PUTATIVE SENSOR-LIKE
HISTIDINE KINASE
YOJN

(Escherichia
coli) 		PF01627
(Hpt) 		4 THR A 840
LEU A 844
VAL A 847
LEU A 851
 None
 0.67A 1fbmE-1sr2A:
undetectable		 1fbmE-1sr2A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1suu DNA GYRASE SUBUNIT A

(Borreliella
burgdorferi) 		PF03989
(DNA_gyraseA_C) 		4 LEU A 551
VAL A 510
LEU A 518
GLN A 586
 None
 0.87A 1fbmE-1suuA:
undetectable		 1fbmE-1suuA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1td6 HYPOTHETICAL PROTEIN
MG237 HOMOLOG

(Mycoplasma
pneumoniae) 		PF11428
(DUF3196) 		4 LEU A  88
VAL A  91
LEU A  95
GLN A  98
 None
 0.70A 1fbmE-1td6A:
undetectable		 1fbmE-1td6A:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tp7 GENOME POLYPROTEIN

(Rhinovirus A) 		PF00680
(RdRP_1) 		4 LEU A 254
VAL A 253
LEU A  85
GLN A  84
 None
 0.90A 1fbmE-1tp7A:
undetectable		 1fbmE-1tp7A:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u6g TIP120 PROTEIN

(Homo sapiens) 		PF08623
(TIP120) 		4 THR C 611
LEU C 612
VAL C 647
LEU C 648
 None
 0.84A 1fbmE-1u6gC:
undetectable		 1fbmE-1u6gC:
3.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ufa TT1467 PROTEIN

(Thermus
thermophilus) 		PF03065
(Glyco_hydro_57)
PF09210
(DUF1957) 		4 THR A  35
LEU A  39
VAL A  42
LEU A  46
 None
 0.46A 1fbmE-1ufaA:
undetectable		 1fbmE-1ufaA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vc2 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Thermus
thermophilus) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 THR A 150
LEU A 154
VAL A 157
LEU A 161
 None
 0.59A 1fbmE-1vc2A:
undetectable		 1fbmE-1vc2A:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vhz ADP COMPOUNDS
HYDROLASE NUDE

(Escherichia
coli) 		PF00293
(NUDIX) 		4 LEU A 173
VAL A 176
LEU A 180
GLN A 183
 None
 0.86A 1fbmE-1vhzA:
undetectable		 1fbmE-1vhzA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w55 ISPD/ISPF
BIFUNCTIONAL ENZYME

(Campylobacter
jejuni) 		PF01128
(IspD)
PF02542
(YgbB) 		4 THR A  38
LEU A  41
VAL A 102
LEU A 106
 None
 0.79A 1fbmE-1w55A:
undetectable		 1fbmE-1w55A:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wch PROTEIN TYROSINE
PHOSPHATASE,
NON-RECEPTOR TYPE 13

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 THR A2193
LEU A2197
VAL A2200
LEU A2204
 None
 0.76A 1fbmE-1wchA:
undetectable		 1fbmE-1wchA:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wek HYPOTHETICAL PROTEIN
TT1465

(Thermus
thermophilus) 		PF03641
(Lysine_decarbox) 		4 THR A 144
LEU A 148
VAL A 151
LEU A 155
 PO4  A 501 (-3.9A)
None
None
None
 0.69A 1fbmE-1wekA:
undetectable		 1fbmE-1wekA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfb ALDOLASE C

(Homo sapiens) 		PF00274
(Glycolytic) 		4 THR A 206
LEU A 210
VAL A 213
LEU A 217
 None
 0.49A 1fbmE-1xfbA:
undetectable		 1fbmE-1xfbA:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y9u PUTATIVE IRON
BINDING PROTEIN

(Bordetella
pertussis) 		PF13343
(SBP_bac_6) 		4 THR A 160
LEU A 164
VAL A 167
LEU A 171
 None
 0.72A 1fbmE-1y9uA:
undetectable		 1fbmE-1y9uA:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Pseudomonas
aeruginosa) 		PF01467
(CTP_transf_like) 		4 THR A  85
LEU A  89
VAL A  92
LEU A  96
 None
 0.48A 1fbmE-1yulA:
undetectable		 1fbmE-1yulA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zq3 HOMEOTIC BICOID
PROTEIN

(Drosophila
melanogaster) 		PF00046
(Homeobox) 		5 THR P  28
LEU P  27
VAL P  46
LEU P  17
GLN P  13
 None
 1.46A 1fbmE-1zq3P:
undetectable		 1fbmE-1zq3P:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zy9 ALPHA-GALACTOSIDASE

(Thermotoga
maritima) 		PF02065
(Melibiase) 		4 THR A  51
LEU A 132
VAL A 127
LEU A 100
 None
 0.91A 1fbmE-1zy9A:
undetectable		 1fbmE-1zy9A:
5.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a9s COMPETENCE/DAMAGE-IN
DUCIBLE PROTEIN CINA

(Agrobacterium
fabrum) 		PF02464
(CinA) 		4 THR A 146
LEU A 150
VAL A 153
LEU A 157
 None
 0.67A 1fbmE-2a9sA:
undetectable		 1fbmE-2a9sA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bl2 V-TYPE SODIUM ATP
SYNTHASE SUBUNIT K

(Enterococcus
hirae) 		PF00137
(ATP-synt_C) 		4 THR A 140
LEU A 144
VAL A 147
LEU A 151
 None
 0.71A 1fbmE-2bl2A:
undetectable		 1fbmE-2bl2A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cu1 MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE 2

(Homo sapiens) 		PF00564
(PB1) 		4 LEU A  71
VAL A  68
LEU A  64
GLN A  61
 None
 0.89A 1fbmE-2cu1A:
undetectable		 1fbmE-2cu1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d2i GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Synechococcus
sp.) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 THR A 156
LEU A 160
VAL A 163
LEU A 167
 SO4  A1339 ( 4.3A)
None
None
None
 0.61A 1fbmE-2d2iA:
undetectable		 1fbmE-2d2iA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dr1 386AA LONG
HYPOTHETICAL SERINE
AMINOTRANSFERASE

(Pyrococcus
horikoshii) 		PF00266
(Aminotran_5) 		4 LEU A 372
VAL A 375
LEU A 379
GLN A 382
 None
 0.57A 1fbmE-2dr1A:
undetectable		 1fbmE-2dr1A:
7.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e2a PROTEIN (ENZYME IIA)

(Lactococcus
lactis) 		PF02255
(PTS_IIA) 		4 THR A  85
LEU A  89
VAL A  92
LEU A  96
 None
 0.84A 1fbmE-2e2aA:
undetectable		 1fbmE-2e2aA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gm5 TRANSPOSON
GAMMA-DELTA
RESOLVASE

(Escherichia
coli) 		PF00239
(Resolvase) 		4 LEU A  23
VAL A  20
LEU A  16
GLN A  13
 None
 0.88A 1fbmE-2gm5A:
undetectable		 1fbmE-2gm5A:
25.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2huj LIN2004 PROTEIN

(Listeria
innocua) 		PF08807
(DUF1798) 		4 THR A 103
LEU A 107
VAL A 110
LEU A 114
 None
 0.77A 1fbmE-2hujA:
undetectable		 1fbmE-2hujA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ihm DNA POLYMERASE MU

(Mus musculus) 		PF10391
(DNA_pol_lambd_f)
PF14716
(HHH_8)
PF14791
(DNA_pol_B_thumb)
PF14792
(DNA_pol_B_palm) 		4 LEU A 347
VAL A 350
LEU A 354
GLN A 357
 None
 0.64A 1fbmE-2ihmA:
undetectable		 1fbmE-2ihmA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jjq UNCHARACTERIZED RNA
METHYLTRANSFERASE
PYRAB10780

(Pyrococcus
abyssi) 		PF05958
(tRNA_U5-meth_tr) 		4 LEU A 268
VAL A 265
LEU A 261
GLN A 252
 None
None
None
SAH  A1406 (-4.1A)
 0.82A 1fbmE-2jjqA:
undetectable		 1fbmE-2jjqA:
6.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m0m MINOR AMPULLATE
FIBROIN 1

(Nephila
antipodiana) 		PF11260
(Spidroin_MaSp) 		5 THR A  52
LEU A  55
VAL A  58
LEU A  62
GLN A  65
 None
 1.22A 1fbmE-2m0mA:
undetectable		 1fbmE-2m0mA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nps SYNTAXIN-6

(Homo sapiens) 		no annotation 4 THR D 211
LEU D 215
VAL D 218
LEU D 222
 None
 0.71A 1fbmE-2npsD:
3.8		 1fbmE-2npsD:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2npt MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE 2

(Homo sapiens) 		PF00564
(PB1) 		4 LEU B 106
VAL B 103
LEU B  99
GLN B  96
 None
 0.88A 1fbmE-2nptB:
undetectable		 1fbmE-2nptB:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o3b NUCLEASE

(Nostoc sp. PCC
7120) 		PF01223
(Endonuclease_NS) 		4 THR A 158
LEU A 162
LEU A 169
GLN A 172
 None
 0.85A 1fbmE-2o3bA:
undetectable		 1fbmE-2o3bA:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o42 M11L PROTEIN

(Myxoma virus) 		PF11099
(M11L) 		4 THR A  83
LEU A  87
VAL A  90
LEU A  94
 None
 0.80A 1fbmE-2o42A:
undetectable		 1fbmE-2o42A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR

(Arabidopsis
thaliana) 		PF00448
(SRP54)
PF02881
(SRP54_N) 		4 THR A  36
LEU A  40
VAL A  42
LEU A  46
 None
 0.68A 1fbmE-2og2A:
undetectable		 1fbmE-2og2A:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okj GLUTAMATE
DECARBOXYLASE 1

(Homo sapiens) 		PF00282
(Pyridoxal_deC) 		4 THR A 113
LEU A 117
VAL A 120
LEU A 124
 None
 0.62A 1fbmE-2okjA:
undetectable		 1fbmE-2okjA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okk GLUTAMATE
DECARBOXYLASE 2

(Homo sapiens) 		PF00282
(Pyridoxal_deC) 		4 THR A 107
LEU A 111
VAL A 114
LEU A 118
 None
 0.72A 1fbmE-2okkA:
undetectable		 1fbmE-2okkA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oy0 METHYLTRANSFERASE

(West Nile virus) 		PF01728
(FtsJ) 		4 THR A 161
LEU A 165
VAL A 168
LEU A 172
 None
 0.64A 1fbmE-2oy0A:
undetectable		 1fbmE-2oy0A:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pl3 PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX10

(Homo sapiens) 		PF00270
(DEAD) 		4 THR A 120
LEU A 124
VAL A 127
LEU A 131
 ADP  A 300 (-3.6A)
None
None
None
 0.75A 1fbmE-2pl3A:
undetectable		 1fbmE-2pl3A:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2px5 GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)]

(Murray Valley
encephalitis
virus) 		PF01728
(FtsJ) 		4 THR A 161
LEU A 165
VAL A 168
LEU A 172
 None
 0.73A 1fbmE-2px5A:
undetectable		 1fbmE-2px5A:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qop HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ACRR

(Escherichia
coli) 		PF00440
(TetR_N)
PF08361
(TetR_C_2) 		4 THR A  12
VAL A  19
LEU A  23
GLN A  26
 None
 0.86A 1fbmE-2qopA:
undetectable		 1fbmE-2qopA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rci TYPE-2BA CYTOLYTIC
DELTA-ENDOTOXIN

(Bacillus
thuringiensis) 		PF01338
(Bac_thur_toxin) 		4 THR A  95
LEU A 220
LEU A  60
GLN A  56
 THR  A  95 ( 0.8A)
LEU  A 220 ( 0.6A)
LEU  A  60 ( 0.5A)
GLN  A  56 ( 0.6A)
 0.74A 1fbmE-2rciA:
undetectable		 1fbmE-2rciA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2spc SPECTRIN

(Drosophila
melanogaster) 		PF00435
(Spectrin) 		4 LEU A  61
VAL A  64
LEU A  68
GLN A  71
 None
 0.80A 1fbmE-2spcA:
2.7		 1fbmE-2spcA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vqr PUTATIVE SULFATASE

(Rhizobium
leguminosarum) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		4 LEU A 301
VAL A 304
LEU A 308
GLN A 313
 None
 0.89A 1fbmE-2vqrA:
undetectable		 1fbmE-2vqrA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vqx METALLOPROTEINASE

(Serratia
proteamaculans) 		PF01447
(Peptidase_M4)
PF02868
(Peptidase_M4_C)
PF16485
(PLN_propep) 		4 LEU A 188
VAL A 191
LEU A 195
GLN A 198
 None
 0.88A 1fbmE-2vqxA:
undetectable		 1fbmE-2vqxA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w83 C-JUN-AMINO-TERMINAL
KINASE-INTERACTING
PROTEIN 4

(Homo sapiens) 		PF16471
(JIP_LZII) 		4 THR C 409
LEU C 413
VAL C 416
LEU C 420
 None
 0.53A 1fbmE-2w83C:
3.8		 1fbmE-2w83C:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wtz UDP-N-ACETYLMURAMOYL
-L-ALANYL-D-GLUTAMAT
E--2,6-DIAMINOPIMELA
TE LIGASE

(Mycobacterium
tuberculosis) 		PF01225
(Mur_ligase)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M) 		4 LEU A 414
VAL A 497
LEU A 390
GLN A 380
 None
 0.80A 1fbmE-2wtzA:
undetectable		 1fbmE-2wtzA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wvw RBCX PROTEIN

(Anabaena sp. CA
= ATCC 33047) 		PF02341
(RcbX) 		4 THR I  19
LEU I  23
VAL I  26
LEU I  30
 None
 0.85A 1fbmE-2wvwI:
undetectable		 1fbmE-2wvwI:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x9p PIMD PROTEIN

(Streptomyces
natalensis) 		PF00067
(p450) 		4 LEU A 198
VAL A 195
LEU A 191
GLN A 188
 None
 0.81A 1fbmE-2x9pA:
undetectable		 1fbmE-2x9pA:
9.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos taurus) 		PF02238
(COX7a) 		4 THR J  27
LEU J  31
VAL J  34
LEU J  38
 None
 0.50A 1fbmE-2y69J:
2.6		 1fbmE-2y69J:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zd2 ATP12 ATPASE

(Paracoccus
denitrificans) 		PF07542
(ATP12) 		4 THR A1046
LEU A1044
VAL A1027
LEU A1034
 None
 0.87A 1fbmE-2zd2A:
undetectable		 1fbmE-2zd2A:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a0h PHOTOSYSTEM II
REACTION CENTER
PROTEIN I

(Thermosynechococcus
vulcanus) 		PF02532
(PsbI) 		4 THR I  13
LEU I  17
VAL I  20
LEU I  24
 None
 0.71A 1fbmE-3a0hI:
2.3		 1fbmE-3a0hI:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aqc COMPONENT B OF
HEXAPRENYL
DIPHOSPHATE SYNTHASE

(Micrococcus
luteus) 		PF00348
(polyprenyl_synt) 		4 THR B 237
LEU B 240
LEU B 247
GLN B 250
 None
 0.74A 1fbmE-3aqcB:
undetectable		 1fbmE-3aqcB:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY

(Thermus
thermophilus) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		4 LEU A  86
VAL A  89
LEU A  93
GLN A  96
 None
 0.68A 1fbmE-3b02A:
undetectable		 1fbmE-3b02A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)

(Synechococcus
elongatus) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 THR A 156
LEU A 160
VAL A 163
LEU A 167
 SO4  A1339 (-3.7A)
None
None
None
 0.59A 1fbmE-3b20A:
undetectable		 1fbmE-3b20A:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bdz P450CIN

(Citrobacter
braakii) 		PF00067
(p450) 		4 THR A 243
LEU A 247
VAL A 250
LEU A 254
 HEM  A 450 (-4.3A)
None
None
None
 0.62A 1fbmE-3bdzA:
undetectable		 1fbmE-3bdzA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A

(Oryctolagus
cuniculus) 		PF00274
(Glycolytic) 		4 THR A 205
LEU A 209
VAL A 212
LEU A 216
 None
 0.55A 1fbmE-3bv4A:
undetectable		 1fbmE-3bv4A:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c8t FUMARATE LYASE

(Chelativorans
sp. BNC1) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		4 THR A 247
LEU A 251
VAL A 254
LEU A 258
 None
 0.72A 1fbmE-3c8tA:
undetectable		 1fbmE-3c8tA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2

(Rattus
norvegicus) 		PF01150
(GDA1_CD39) 		4 THR A 136
LEU A 140
VAL A 143
LEU A 147
 None
 0.56A 1fbmE-3cj1A:
undetectable		 1fbmE-3cj1A:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cl3 ORF K13

(Human
gammaherpesvirus
8) 		PF01335
(DED) 		4 THR A   3
LEU A   7
VAL A  10
LEU A  14
 None
 0.82A 1fbmE-3cl3A:
undetectable		 1fbmE-3cl3A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3csk PROBABLE
DIPEPTIDYL-PEPTIDASE
3

(Saccharomyces
cerevisiae) 		PF03571
(Peptidase_M49) 		4 THR A  84
LEU A  88
VAL A  91
LEU A  95
 None
 0.55A 1fbmE-3cskA:
undetectable		 1fbmE-3cskA:
5.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3doc GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Brucella
abortus) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 THR A 154
LEU A 158
VAL A 161
LEU A 165
 None
 0.54A 1fbmE-3docA:
undetectable		 1fbmE-3docA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwm 9.5 KDA CULTURE
FILTRATE ANTIGEN
CFP10A

(Mycobacterium
tuberculosis) 		PF02597
(ThiS) 		4 THR A  76
LEU A  28
VAL A  31
LEU A  35
 None
 0.54A 1fbmE-3dwmA:
undetectable		 1fbmE-3dwmA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e97 TRANSCRIPTIONAL
REGULATOR, CRP/FNR
FAMILY

(Deinococcus
geothermalis) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		4 THR A 147
LEU A 151
VAL A 154
GLN A 161
 None
 0.92A 1fbmE-3e97A:
undetectable		 1fbmE-3e97A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e97 TRANSCRIPTIONAL
REGULATOR, CRP/FNR
FAMILY

(Deinococcus
geothermalis) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		4 THR A 147
VAL A 154
LEU A 158
GLN A 161
 None
 0.87A 1fbmE-3e97A:
undetectable		 1fbmE-3e97A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ek5 URIDYLATE KINASE

(Xanthomonas
campestris) 		PF00696
(AA_kinase) 		4 LEU A  79
VAL A  82
LEU A  86
GLN A  89
 None
 0.72A 1fbmE-3ek5A:
undetectable		 1fbmE-3ek5A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3evc RNA-DIRECTED RNA
POLYMERASE NS5

(Yellow fever
virus) 		PF01728
(FtsJ) 		4 THR A 161
LEU A 165
VAL A 168
LEU A 172
 None
 0.67A 1fbmE-3evcA:
undetectable		 1fbmE-3evcA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f6p TRANSCRIPTIONAL
REGULATORY PROTEIN
YYCF

(Bacillus
subtilis) 		PF00072
(Response_reg) 		4 THR A 106
LEU A 110
VAL A 113
LEU A 117
 None
 0.68A 1fbmE-3f6pA:
undetectable		 1fbmE-3f6pA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE

(Burkholderia
pseudomallei) 		PF00698
(Acyl_transf_1) 		4 THR A 109
LEU A 113
LEU A 120
GLN A 123
 None
 0.84A 1fbmE-3g87A:
undetectable		 1fbmE-3g87A:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h74 PYRIDOXAL KINASE

(Lactobacillus
plantarum) 		PF08543
(Phos_pyr_kin) 		4 THR A 211
LEU A 215
VAL A 218
LEU A 222
 GOL  A 283 ( 4.7A)
None
None
None
 0.74A 1fbmE-3h74A:
undetectable		 1fbmE-3h74A:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hvw DIGUANYLATE-CYCLASE
(DGC)

(Pseudomonas
aeruginosa) 		PF00990
(GGDEF) 		4 THR A 238
LEU A 250
VAL A 196
LEU A 292
 None
 0.81A 1fbmE-3hvwA:
undetectable		 1fbmE-3hvwA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ibr BACTERIOPHYTOCHROME

(Pseudomonas
aeruginosa) 		PF00360
(PHY)
PF01590
(GAF)
PF08446
(PAS_2) 		4 THR A 140
LEU A 144
VAL A 147
LEU A 151
 None
 0.68A 1fbmE-3ibrA:
undetectable		 1fbmE-3ibrA:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iee PUTATIVE EXPORTED
PROTEIN

(Bacteroides
fragilis) 		no annotation 4 LEU A 145
VAL A 148
LEU A 152
GLN A 155
 None
 0.59A 1fbmE-3ieeA:
undetectable		 1fbmE-3ieeA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ifq PLAKOGLOBIN

(Homo sapiens) 		PF00514
(Arm) 		4 LEU A 389
VAL A 392
LEU A 396
GLN A 399
 None
 0.80A 1fbmE-3ifqA:
undetectable		 1fbmE-3ifqA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k30 HISTAMINE
DEHYDROGENASE

(Pimelobacter
simplex) 		PF00724
(Oxidored_FMN)
PF07992
(Pyr_redox_2) 		4 LEU A 536
VAL A 539
LEU A 543
GLN A 546
 None
 0.88A 1fbmE-3k30A:
undetectable		 1fbmE-3k30A:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ksd GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1

(Staphylococcus
aureus) 		no annotation 4 THR Q 152
LEU Q 156
VAL Q 159
LEU Q 163
 None
 0.57A 1fbmE-3ksdQ:
undetectable		 1fbmE-3ksdQ:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kx6 FRUCTOSE-BISPHOSPHAT
E ALDOLASE

(Babesia bovis) 		PF00274
(Glycolytic) 		4 THR A 204
LEU A 208
VAL A 211
LEU A 215
 None
 0.51A 1fbmE-3kx6A:
undetectable		 1fbmE-3kx6A:
6.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Bartonella
henselae) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 THR A 154
LEU A 158
VAL A 161
LEU A 165
 None
 0.63A 1fbmE-3l0dA:
undetectable		 1fbmE-3l0dA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lhq ACRAB OPERON
REPRESSOR (TETR/ACRR
FAMILY)

(Salmonella
enterica) 		PF00440
(TetR_N)
PF08361
(TetR_C_2) 		4 THR A  12
VAL A  19
LEU A  23
GLN A  26
 None
 0.69A 1fbmE-3lhqA:
undetectable		 1fbmE-3lhqA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lkz NON-STRUCTURAL
PROTEIN 5

(West Nile virus) 		PF01728
(FtsJ) 		4 THR A 161
LEU A 165
VAL A 168
LEU A 172
 None
 0.60A 1fbmE-3lkzA:
undetectable		 1fbmE-3lkzA:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE

(Bartonella
henselae) 		PF00274
(Glycolytic) 		4 THR A 199
LEU A 203
VAL A 206
LEU A 210
 None
 0.59A 1fbmE-3mmtA:
undetectable		 1fbmE-3mmtA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE

(Klebsiella
pneumoniae) 		PF00266
(Aminotran_5) 		4 THR A 379
LEU A 383
VAL A 386
LEU A 390
 None
 0.58A 1fbmE-3nnkA:
undetectable		 1fbmE-3nnkA:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nvl 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Trypanosoma
brucei) 		PF01676
(Metalloenzyme)
PF06415
(iPGM_N) 		4 THR A 435
LEU A 439
VAL A 442
LEU A 446
 None
 0.57A 1fbmE-3nvlA:
undetectable		 1fbmE-3nvlA:
6.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o8o 6-PHOSPHOFRUCTOKINAS
E SUBUNIT BETA

(Saccharomyces
cerevisiae) 		PF00365
(PFK) 		4 THR B 497
LEU B 501
VAL B 504
LEU B 508
 None
 0.87A 1fbmE-3o8oB:
undetectable		 1fbmE-3o8oB:
5.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oja LEUCINE-RICH IMMUNE
MOLECULE 1

(Anopheles
gambiae) 		PF00560
(LRR_1) 		4 THR A 493
LEU A 497
LEU A 504
GLN A 507
 None
 0.57A 1fbmE-3ojaA:
4.0		 1fbmE-3ojaA:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3op7 AMINOTRANSFERASE
CLASS I AND II

(Streptococcus
suis) 		PF00155
(Aminotran_1_2) 		4 LEU A  56
VAL A 256
LEU A 260
GLN A 263
 None
 0.78A 1fbmE-3op7A:
undetectable		 1fbmE-3op7A:
9.19