SIMILAR PATTERNS OF AMINO ACIDS FOR 1FBM_B_RTLB951_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a5c FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE

(Plasmodium
falciparum) 		PF00274
(Glycolytic) 		4 THR A 212
LEU A 216
VAL A 219
LEU A 223
 None
 0.73A 1fbmD-1a5cA:
0.0		 1fbmD-1a5cA:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a5c FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE

(Plasmodium
falciparum) 		PF00274
(Glycolytic) 		4 THR A 262
LEU A 263
VAL A 267
LEU A 271
 None
 0.98A 1fbmD-1a5cA:
0.0		 1fbmD-1a5cA:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1at3 HERPES SIMPLEX VIRUS
TYPE II PROTEASE

(Human
alphaherpesvirus
2) 		PF00716
(Peptidase_S21) 		4 THR A 210
LEU A 213
VAL A  59
LEU A 151
 None
 0.91A 1fbmD-1at3A:
0.0		 1fbmD-1at3A:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1awc PROTEIN (GA BINDING
PROTEIN BETA 1)

(Mus musculus) 		PF12796
(Ank_2)
PF13637
(Ank_4) 		4 THR B  54
LEU B  57
VAL B  22
LEU B  25
 None
 0.86A 1fbmD-1awcB:
0.0		 1fbmD-1awcB:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aye PROCARBOXYPEPTIDASE
A2

(Homo sapiens) 		PF00246
(Peptidase_M14)
PF02244
(Propep_M14) 		4 THR A  54
LEU A  32
VAL A  33
LEU A  25
 None
 0.97A 1fbmD-1ayeA:
0.0		 1fbmD-1ayeA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b9b PROTEIN
(TRIOSEPHOSPHATE
ISOMERASE)

(Thermotoga
maritima) 		PF00121
(TIM) 		4 THR A  46
LEU A  48
VAL A  51
LEU A  55
 None
 0.86A 1fbmD-1b9bA:
undetectable		 1fbmD-1b9bA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bct BACTERIORHODOPSIN

(Halobacterium
salinarum) 		PF01036
(Bac_rhodopsin) 		4 THR A 170
LEU A 174
VAL A 177
LEU A 181
 None
 0.68A 1fbmD-1bctA:
1.8		 1fbmD-1bctA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1brr PROTEIN
(BACTERIORHODOPSIN)

(Halobacterium
salinarum) 		PF01036
(Bac_rhodopsin) 		4 THR A 170
LEU A 174
VAL A 177
LEU A 181
 None
 0.70A 1fbmD-1brrA:
0.0		 1fbmD-1brrA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE

(Drosophila
melanogaster) 		PF00274
(Glycolytic) 		4 THR A 205
LEU A 209
VAL A 212
LEU A 216
 None
 0.62A 1fbmD-1fbaA:
0.0		 1fbmD-1fbaA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fdj FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE

(Oryctolagus
cuniculus) 		PF00274
(Glycolytic) 		4 THR A1205
LEU A1209
VAL A1212
LEU A1216
 None
 0.55A 1fbmD-1fdjA:
0.0		 1fbmD-1fdjA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h3d ATP-PHOSPHORIBOSYLTR
ANSFERASE

(Escherichia
coli) 		PF01634
(HisG)
PF08029
(HisG_C) 		4 THR A 235
LEU A 238
VAL A 241
LEU A 245
 None
 0.97A 1fbmD-1h3dA:
undetectable		 1fbmD-1h3dA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jqk CARBON MONOXIDE
DEHYDROGENASE

(Rhodospirillum
rubrum) 		PF03063
(Prismane) 		4 THR A 152
LEU A 148
VAL A 145
LEU A 141
 None
 0.97A 1fbmD-1jqkA:
undetectable		 1fbmD-1jqkA:
6.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mpx ALPHA-AMINO ACID
ESTER HYDROLASE

(Xanthomonas
citri) 		PF02129
(Peptidase_S15)
PF08530
(PepX_C) 		4 THR A 577
LEU A 494
VAL A 584
LEU A 427
 None
 0.97A 1fbmD-1mpxA:
undetectable		 1fbmD-1mpxA:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n11 ANKYRIN

(Homo sapiens) 		PF00023
(Ank)
PF12796
(Ank_2)
PF13637
(Ank_4)
PF13857
(Ank_5) 		4 THR A 783
LEU A 786
VAL A 750
LEU A 753
 None
 0.85A 1fbmD-1n11A:
undetectable		 1fbmD-1n11A:
6.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q90 CYTOCHROME B6F
COMPLEX SUBUNIT PETG

(Chlamydomonas
reinhardtii) 		PF02529
(PetG) 		4 THR G  17
LEU G  13
VAL G  10
LEU G   6
 BCR  B 904 ( 4.4A)
BCR  B 904 ( 4.3A)
None
None
 0.98A 1fbmD-1q90G:
undetectable		 1fbmD-1q90G:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6a GENOME POLYPROTEIN

(Dengue virus) 		PF01728
(FtsJ) 		4 THR A 161
LEU A 165
VAL A 168
LEU A 172
 None
 0.69A 1fbmD-1r6aA:
undetectable		 1fbmD-1r6aA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sj5 CONSERVED
HYPOTHETICAL PROTEIN
TM0160

(Thermotoga
maritima) 		PF02577
(DNase-RNase) 		4 THR A  57
LEU A  61
VAL A  64
LEU A  68
 None
 0.80A 1fbmD-1sj5A:
undetectable		 1fbmD-1sj5A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sma MALTOGENIC AMYLASE

(Thermus sp.
IM6501) 		PF00128
(Alpha-amylase)
PF02903
(Alpha-amylase_N)
PF16657
(Malt_amylase_C) 		4 THR A  56
LEU A  39
VAL A  75
LEU A  23
 None
 0.94A 1fbmD-1smaA:
undetectable		 1fbmD-1smaA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1szn ALPHA-GALACTOSIDASE

(Trichoderma
reesei) 		PF16499
(Melibiase_2) 		4 THR A 267
LEU A 266
VAL A 261
LEU A 259
 None
 0.92A 1fbmD-1sznA:
undetectable		 1fbmD-1sznA:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u6g TIP120 PROTEIN

(Homo sapiens) 		PF08623
(TIP120) 		4 THR C 611
LEU C 612
VAL C 647
LEU C 648
 None
 0.92A 1fbmD-1u6gC:
undetectable		 1fbmD-1u6gC:
3.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ufa TT1467 PROTEIN

(Thermus
thermophilus) 		PF03065
(Glyco_hydro_57)
PF09210
(DUF1957) 		4 THR A  35
LEU A  39
VAL A  42
LEU A  46
 None
 0.54A 1fbmD-1ufaA:
undetectable		 1fbmD-1ufaA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vc2 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Thermus
thermophilus) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 THR A 150
LEU A 154
VAL A 157
LEU A 161
 None
 0.79A 1fbmD-1vc2A:
undetectable		 1fbmD-1vc2A:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w55 ISPD/ISPF
BIFUNCTIONAL ENZYME

(Campylobacter
jejuni) 		PF01128
(IspD)
PF02542
(YgbB) 		4 THR A  38
LEU A  41
VAL A 102
LEU A 106
 None
 0.90A 1fbmD-1w55A:
undetectable		 1fbmD-1w55A:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wch PROTEIN TYROSINE
PHOSPHATASE,
NON-RECEPTOR TYPE 13

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 THR A2193
LEU A2197
VAL A2200
LEU A2204
 None
 0.75A 1fbmD-1wchA:
undetectable		 1fbmD-1wchA:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wek HYPOTHETICAL PROTEIN
TT1465

(Thermus
thermophilus) 		PF03641
(Lysine_decarbox) 		4 THR A 144
LEU A 148
VAL A 151
LEU A 155
 PO4  A 501 (-3.9A)
None
None
None
 0.54A 1fbmD-1wekA:
undetectable		 1fbmD-1wekA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfb ALDOLASE C

(Homo sapiens) 		PF00274
(Glycolytic) 		4 THR A 206
LEU A 210
VAL A 213
LEU A 217
 None
 0.63A 1fbmD-1xfbA:
undetectable		 1fbmD-1xfbA:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y9u PUTATIVE IRON
BINDING PROTEIN

(Bordetella
pertussis) 		PF13343
(SBP_bac_6) 		4 THR A 160
LEU A 164
VAL A 167
LEU A 171
 None
 0.68A 1fbmD-1y9uA:
undetectable		 1fbmD-1y9uA:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Pseudomonas
aeruginosa) 		PF01467
(CTP_transf_like) 		4 THR A  85
LEU A  89
VAL A  92
LEU A  96
 None
 0.52A 1fbmD-1yulA:
undetectable		 1fbmD-1yulA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a9s COMPETENCE/DAMAGE-IN
DUCIBLE PROTEIN CINA

(Agrobacterium
fabrum) 		PF02464
(CinA) 		4 THR A 146
LEU A 150
VAL A 153
LEU A 157
 None
 0.67A 1fbmD-2a9sA:
undetectable		 1fbmD-2a9sA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bl2 V-TYPE SODIUM ATP
SYNTHASE SUBUNIT K

(Enterococcus
hirae) 		PF00137
(ATP-synt_C) 		4 THR A 140
LEU A 144
VAL A 147
LEU A 151
 None
 0.58A 1fbmD-2bl2A:
undetectable		 1fbmD-2bl2A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d2i GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Synechococcus
sp.) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 THR A 156
LEU A 160
VAL A 163
LEU A 167
 SO4  A1339 ( 4.3A)
None
None
None
 0.78A 1fbmD-2d2iA:
undetectable		 1fbmD-2d2iA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g0j HYPOTHETICAL PROTEIN
SMU.848

(Streptococcus
mutans) 		PF04327
(Peptidase_Prp) 		4 THR A  19
LEU A  18
VAL A  36
LEU A  39
 None
 0.96A 1fbmD-2g0jA:
undetectable		 1fbmD-2g0jA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hg4 6-DEOXYERYTHRONOLIDE
B SYNTHASE

(Saccharopolyspora
erythraea) 		PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF08990
(Docking)
PF16197
(KAsynt_C_assoc) 		4 THR A  19
LEU A  23
VAL A  26
LEU A  30
 None
 0.79A 1fbmD-2hg4A:
undetectable		 1fbmD-2hg4A:
3.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kl4 BH2032 PROTEIN

(Bacillus
halodurans) 		PF08818
(DUF1801) 		4 THR A  23
LEU A  27
VAL A  30
LEU A  37
 None
 0.95A 1fbmD-2kl4A:
undetectable		 1fbmD-2kl4A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m0m MINOR AMPULLATE
FIBROIN 1

(Nephila
antipodiana) 		PF11260
(Spidroin_MaSp) 		4 THR A  52
LEU A  55
VAL A  58
LEU A  62
 None
 0.88A 1fbmD-2m0mA:
undetectable		 1fbmD-2m0mA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nps SYNTAXIN-6

(Homo sapiens) 		no annotation 4 THR D 211
LEU D 215
VAL D 218
LEU D 222
 None
 0.65A 1fbmD-2npsD:
undetectable		 1fbmD-2npsD:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR

(Arabidopsis
thaliana) 		PF00448
(SRP54)
PF02881
(SRP54_N) 		4 THR A  36
LEU A  40
VAL A  42
LEU A  46
 None
 0.66A 1fbmD-2og2A:
undetectable		 1fbmD-2og2A:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okj GLUTAMATE
DECARBOXYLASE 1

(Homo sapiens) 		PF00282
(Pyridoxal_deC) 		4 THR A 113
LEU A 117
VAL A 120
LEU A 124
 None
 0.78A 1fbmD-2okjA:
undetectable		 1fbmD-2okjA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okk GLUTAMATE
DECARBOXYLASE 2

(Homo sapiens) 		PF00282
(Pyridoxal_deC) 		4 THR A 107
LEU A 111
VAL A 114
LEU A 118
 None
 0.86A 1fbmD-2okkA:
undetectable		 1fbmD-2okkA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oy0 METHYLTRANSFERASE

(West Nile virus) 		PF01728
(FtsJ) 		4 THR A 161
LEU A 165
VAL A 168
LEU A 172
 None
 0.65A 1fbmD-2oy0A:
undetectable		 1fbmD-2oy0A:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pl3 PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX10

(Homo sapiens) 		PF00270
(DEAD) 		4 THR A 120
LEU A 124
VAL A 127
LEU A 131
 ADP  A 300 (-3.6A)
None
None
None
 0.81A 1fbmD-2pl3A:
undetectable		 1fbmD-2pl3A:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qfv ISOCITRATE
DEHYDROGENASE [NADP]

(Saccharomyces
cerevisiae) 		PF00180
(Iso_dh) 		4 THR A 394
LEU A 398
VAL A 401
LEU A 405
 None
 0.88A 1fbmD-2qfvA:
undetectable		 1fbmD-2qfvA:
7.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w5h SERINE/THREONINE-PRO
TEIN KINASE NEK2

(Homo sapiens) 		PF00069
(Pkinase) 		4 THR A 121
LEU A 120
VAL A 155
LEU A 149
 None
 0.94A 1fbmD-2w5hA:
undetectable		 1fbmD-2w5hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w83 C-JUN-AMINO-TERMINAL
KINASE-INTERACTING
PROTEIN 4

(Homo sapiens) 		PF16471
(JIP_LZII) 		4 THR C 409
LEU C 413
VAL C 416
LEU C 420
 None
 0.53A 1fbmD-2w83C:
undetectable		 1fbmD-2w83C:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wvw RBCX PROTEIN

(Anabaena sp. CA
= ATCC 33047) 		PF02341
(RcbX) 		4 THR I  19
LEU I  23
VAL I  26
LEU I  30
 None
 0.65A 1fbmD-2wvwI:
undetectable		 1fbmD-2wvwI:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos taurus) 		PF02238
(COX7a) 		4 THR J  27
LEU J  31
VAL J  34
LEU J  38
 None
 0.37A 1fbmD-2y69J:
undetectable		 1fbmD-2y69J:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yr5 PRO-ENZYME OF
L-PHENYLALANINE
OXIDASE

(Pseudomonas sp.
P-501) 		no annotation 4 THR A 202
LEU A 206
VAL A 209
LEU A 213
 None
 0.70A 1fbmD-2yr5A:
undetectable		 1fbmD-2yr5A:
5.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a0h PHOTOSYSTEM II
REACTION CENTER
PROTEIN I

(Thermosynechococcus
vulcanus) 		PF02532
(PsbI) 		4 THR I  13
LEU I  17
VAL I  20
LEU I  24
 None
 0.76A 1fbmD-3a0hI:
undetectable		 1fbmD-3a0hI:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)

(Synechococcus
elongatus) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 THR A 156
LEU A 160
VAL A 163
LEU A 167
 SO4  A1339 (-3.7A)
None
None
None
 0.75A 1fbmD-3b20A:
undetectable		 1fbmD-3b20A:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bdz P450CIN

(Citrobacter
braakii) 		PF00067
(p450) 		4 THR A 243
LEU A 247
VAL A 250
LEU A 254
 HEM  A 450 (-4.3A)
None
None
None
 0.63A 1fbmD-3bdzA:
undetectable		 1fbmD-3bdzA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bu8 TELOMERIC
REPEAT-BINDING
FACTOR 2

(Homo sapiens) 		PF08558
(TRF) 		4 THR A  96
LEU A 100
VAL A 103
LEU A 107
 None
 0.78A 1fbmD-3bu8A:
undetectable		 1fbmD-3bu8A:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A

(Oryctolagus
cuniculus) 		PF00274
(Glycolytic) 		4 THR A 205
LEU A 209
VAL A 212
LEU A 216
 None
 0.68A 1fbmD-3bv4A:
undetectable		 1fbmD-3bv4A:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c8t FUMARATE LYASE

(Chelativorans
sp. BNC1) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		4 THR A 247
LEU A 251
VAL A 254
LEU A 258
 None
 0.64A 1fbmD-3c8tA:
undetectable		 1fbmD-3c8tA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2

(Rattus
norvegicus) 		PF01150
(GDA1_CD39) 		4 THR A 136
LEU A 140
VAL A 143
LEU A 147
 None
 0.46A 1fbmD-3cj1A:
undetectable		 1fbmD-3cj1A:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cl3 ORF K13

(Human
gammaherpesvirus
8) 		PF01335
(DED) 		4 THR A   3
LEU A   7
VAL A  10
LEU A  14
 None
 0.73A 1fbmD-3cl3A:
undetectable		 1fbmD-3cl3A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3csk PROBABLE
DIPEPTIDYL-PEPTIDASE
3

(Saccharomyces
cerevisiae) 		PF03571
(Peptidase_M49) 		4 THR A  84
LEU A  88
VAL A  91
LEU A  95
 None
 0.67A 1fbmD-3cskA:
undetectable		 1fbmD-3cskA:
5.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3doc GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Brucella
abortus) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 THR A 154
LEU A 158
VAL A 161
LEU A 165
 None
 0.65A 1fbmD-3docA:
undetectable		 1fbmD-3docA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ewb 2-ISOPROPYLMALATE
SYNTHASE

(Listeria
monocytogenes) 		PF00682
(HMGL-like) 		4 THR X 227
LEU X 240
VAL X 243
LEU X 247
 None
 0.91A 1fbmD-3ewbX:
undetectable		 1fbmD-3ewbX:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f6p TRANSCRIPTIONAL
REGULATORY PROTEIN
YYCF

(Bacillus
subtilis) 		PF00072
(Response_reg) 		4 THR A 106
LEU A 110
VAL A 113
LEU A 117
 None
 0.61A 1fbmD-3f6pA:
undetectable		 1fbmD-3f6pA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gr3 NITROREDUCTASE

(Bartonella
henselae) 		PF00881
(Nitroreductase) 		4 THR A  56
LEU A  60
VAL A  63
LEU A  67
 None
 0.88A 1fbmD-3gr3A:
undetectable		 1fbmD-3gr3A:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h74 PYRIDOXAL KINASE

(Lactobacillus
plantarum) 		PF08543
(Phos_pyr_kin) 		4 THR A 211
LEU A 215
VAL A 218
LEU A 222
 GOL  A 283 ( 4.7A)
None
None
None
 0.49A 1fbmD-3h74A:
undetectable		 1fbmD-3h74A:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ibr BACTERIOPHYTOCHROME

(Pseudomonas
aeruginosa) 		PF00360
(PHY)
PF01590
(GAF)
PF08446
(PAS_2) 		4 THR A 140
LEU A 144
VAL A 147
LEU A 151
 None
 0.70A 1fbmD-3ibrA:
undetectable		 1fbmD-3ibrA:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ksd GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1

(Staphylococcus
aureus) 		no annotation 4 THR Q 152
LEU Q 156
VAL Q 159
LEU Q 163
 None
 0.87A 1fbmD-3ksdQ:
undetectable		 1fbmD-3ksdQ:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kx6 FRUCTOSE-BISPHOSPHAT
E ALDOLASE

(Babesia bovis) 		PF00274
(Glycolytic) 		4 THR A 204
LEU A 208
VAL A 211
LEU A 215
 None
 0.63A 1fbmD-3kx6A:
undetectable		 1fbmD-3kx6A:
6.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Bartonella
henselae) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 THR A 154
LEU A 158
VAL A 161
LEU A 165
 None
 0.83A 1fbmD-3l0dA:
undetectable		 1fbmD-3l0dA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lrk ALPHA-GALACTOSIDASE
1

(Saccharomyces
cerevisiae) 		PF16499
(Melibiase_2) 		4 THR A 272
LEU A 271
VAL A 266
LEU A 264
 None
 0.95A 1fbmD-3lrkA:
undetectable		 1fbmD-3lrkA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mmt FRUCTOSE-BISPHOSPHAT
E ALDOLASE

(Bartonella
henselae) 		PF00274
(Glycolytic) 		4 THR A 199
LEU A 203
VAL A 206
LEU A 210
 None
 0.64A 1fbmD-3mmtA:
undetectable		 1fbmD-3mmtA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE

(Klebsiella
pneumoniae) 		PF00266
(Aminotran_5) 		4 THR A 379
LEU A 383
VAL A 386
LEU A 390
 None
 0.41A 1fbmD-3nnkA:
undetectable		 1fbmD-3nnkA:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nvl 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Trypanosoma
brucei) 		PF01676
(Metalloenzyme)
PF06415
(iPGM_N) 		4 THR A 435
LEU A 439
VAL A 442
LEU A 446
 None
 0.64A 1fbmD-3nvlA:
undetectable		 1fbmD-3nvlA:
6.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o8o 6-PHOSPHOFRUCTOKINAS
E SUBUNIT BETA

(Saccharomyces
cerevisiae) 		PF00365
(PFK) 		4 THR B 497
LEU B 501
VAL B 504
LEU B 508
 None
 0.71A 1fbmD-3o8oB:
undetectable		 1fbmD-3o8oB:
5.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3odw RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 1

(Homo sapiens) 		PF00621
(RhoGEF) 		4 THR A 655
LEU A 654
VAL A 668
LEU A 670
 None
 0.97A 1fbmD-3odwA:
undetectable		 1fbmD-3odwA:
6.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens) 		PF00563
(EAL)
PF00990
(GGDEF) 		4 THR A 289
LEU A 293
VAL A 296
LEU A 300
 None
 0.72A 1fbmD-3pjxA:
undetectable		 1fbmD-3pjxA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qy9 DIHYDRODIPICOLINATE
REDUCTASE

(Staphylococcus
aureus) 		PF01113
(DapB_N)
PF05173
(DapB_C) 		4 THR A 146
LEU A 150
VAL A 153
LEU A 157
 SO4  A 242 (-3.9A)
None
None
None
 0.82A 1fbmD-3qy9A:
undetectable		 1fbmD-3qy9A:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sho TRANSCRIPTIONAL
REGULATOR, RPIR
FAMILY

(Sphaerobacter
thermophilus) 		PF01380
(SIS) 		4 THR A 235
LEU A 247
VAL A 250
LEU A 254
 None
 0.71A 1fbmD-3shoA:
undetectable		 1fbmD-3shoA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3slk POLYKETIDE SYNTHASE
EXTENDER MODULE 2

(Saccharopolyspora
spinosa) 		PF08240
(ADH_N)
PF08659
(KR)
PF13602
(ADH_zinc_N_2) 		4 THR A  75
LEU A  79
VAL A  82
LEU A  86
 None
 0.54A 1fbmD-3slkA:
undetectable		 1fbmD-3slkA:
4.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3un1 PROBABLE
OXIDOREDUCTASE

(Sinorhizobium
meliloti) 		PF13561
(adh_short_C2) 		4 THR A 149
LEU A 153
VAL A 156
LEU A 160
 None
 0.59A 1fbmD-3un1A:
undetectable		 1fbmD-3un1A:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3un9 NLR FAMILY MEMBER X1

(Homo sapiens) 		PF13516
(LRR_6) 		4 THR A 744
LEU A 745
VAL A 748
LEU A 727
 None
 0.87A 1fbmD-3un9A:
undetectable		 1fbmD-3un9A:
7.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3v2p CARTILAGE
OLIGOMERIZATION
MATRIX PROTEIN
(COILED-COIL DOMAIN)

(Mus musculus) 		PF11598
(COMP) 		4 THR A  40
LEU A  44
VAL A  47
LEU A  51
 STE  A   1 (-4.0A)
STE  A   1 ( 4.5A)
None
STE  A   1 (-4.4A)
 0.49A 1fbmD-3v2pA:
undetectable		 1fbmD-3v2pA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w3s TYPE-2 SERINE--TRNA
LIGASE

(Methanopyrus
kandleri) 		PF00587
(tRNA-synt_2b) 		4 THR A 138
LEU A 137
VAL A 155
LEU A 158
 None
 0.93A 1fbmD-3w3sA:
undetectable		 1fbmD-3w3sA:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wc3 ENDO-1,
4-BETA-GLUCANASE

(Eisenia fetida) 		PF00759
(Glyco_hydro_9) 		4 THR A 288
LEU A 291
VAL A 294
LEU A 298
 GOL  A 506 (-4.7A)
GOL  A 506 ( 4.4A)
None
None
 0.90A 1fbmD-3wc3A:
undetectable		 1fbmD-3wc3A:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zgx CHROMOSOME PARTITION
PROTEIN SMC

(Bacillus
subtilis) 		PF02463
(SMC_N) 		4 THR A 184
LEU A 188
VAL A 191
LEU A 195
 None
 0.69A 1fbmD-3zgxA:
undetectable		 1fbmD-3zgxA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ak9 CPFTSY

(Physcomitrella
patens) 		PF00448
(SRP54)
PF02881
(SRP54_N) 		4 THR A  91
LEU A  95
VAL A  97
LEU A 101
 None
 0.85A 1fbmD-4ak9A:
undetectable		 1fbmD-4ak9A:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d2j FRUCTOSE-BISPHOSPHAT
E ALDOLASE

(Toxoplasma
gondii) 		PF00274
(Glycolytic) 		4 THR A 277
LEU A 281
VAL A 284
LEU A 288
 None
 0.68A 1fbmD-4d2jA:
undetectable		 1fbmD-4d2jA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Bacillus
anthracis) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 THR A 152
LEU A 156
VAL A 159
LEU A 163
 None
 0.51A 1fbmD-4dibA:
undetectable		 1fbmD-4dibA:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gpd APO-D-GLYCERALDEHYDE
-3-PHOSPHATE
DEHYDROGENASE

(Homarus
americanus) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 THR 1 149
LEU 1 153
VAL 1 156
LEU 1 160
 None
 0.81A 1fbmD-4gpd1:
undetectable		 1fbmD-4gpd1:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gxb SORTING NEXIN-17

(Homo sapiens) 		no annotation 4 THR A 139
LEU A 143
VAL A 146
LEU A 150
 None
 0.34A 1fbmD-4gxbA:
undetectable		 1fbmD-4gxbA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h19 MANDELATE RACEMASE

(Agrobacterium
fabrum) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 THR A 103
LEU A 107
VAL A 110
LEU A 114
 CL  A 403 (-3.1A)
None
None
None
 0.51A 1fbmD-4h19A:
undetectable		 1fbmD-4h19A:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hpm BCL-6
COREPRESSOR-LIKE
PROTEIN 1

(Homo sapiens) 		PF16553
(PUFD) 		4 THR A1667
LEU A1666
VAL A1660
LEU A1611
 None
 0.90A 1fbmD-4hpmA:
undetectable		 1fbmD-4hpmA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igi COLLAGEN ALPHA3(VI)

(Mus musculus) 		PF00092
(VWA) 		4 THR A1105
LEU A1109
VAL A1112
LEU A1117
 None
 0.68A 1fbmD-4igiA:
undetectable		 1fbmD-4igiA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jeu SYNTAXIN-BINDING
PROTEIN 1

(Rattus
norvegicus) 		PF00995
(Sec1) 		4 THR A 361
LEU A 365
VAL A 368
LEU A 372
 None
 0.82A 1fbmD-4jeuA:
undetectable		 1fbmD-4jeuA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l9a PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1393C

(Streptococcus
mutans) 		no annotation 4 THR A 258
LEU A 262
VAL A 265
LEU A 269
 None
 0.56A 1fbmD-4l9aA:
undetectable		 1fbmD-4l9aA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m7c TELOMERIC
REPEAT-BINDING
FACTOR 2

(Homo sapiens) 		PF08558
(TRF) 		4 THR A  96
LEU A 100
VAL A 103
LEU A 107
 None
 0.62A 1fbmD-4m7cA:
undetectable		 1fbmD-4m7cA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oec GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE

(Thermococcus
kodakarensis) 		PF03009
(GDPD) 		4 THR A 190
LEU A 194
VAL A 197
LEU A 202
 None
 0.83A 1fbmD-4oecA:
undetectable		 1fbmD-4oecA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ot9 NUCLEAR FACTOR
NF-KAPPA-B P100
SUBUNIT

(Homo sapiens) 		PF12796
(Ank_2) 		4 THR A 684
LEU A 687
VAL A 650
LEU A 653
 None
 0.87A 1fbmD-4ot9A:
undetectable		 1fbmD-4ot9A:
7.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oy4 CHIMERA PROTEIN OF
CALMODULIN, GPF-LIKE
PROTEIN EOSFP, AND
MYOSIN LIGHT CHAIN
KINASE

(Gallus gallus;
Rattus
norvegicus;
Lobophyllia
hemprichii) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		4 THR A  28
LEU A  31
VAL A  34
LEU A  38
 None
 0.50A 1fbmD-4oy4A:
undetectable		 1fbmD-4oy4A:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p6v NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F

(Vibrio cholerae) 		PF00111
(Fer2)
PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		4 THR F  12
LEU F  16
VAL F  19
LEU F  23
 None
 0.71A 1fbmD-4p6vF:
undetectable		 1fbmD-4p6vF:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pq0 FACT COMPLEX SUBUNIT
POB3

(Saccharomyces
cerevisiae) 		PF08512
(Rtt106) 		4 THR A 353
LEU A 357
VAL A 360
LEU A 364
 None
 0.49A 1fbmD-4pq0A:
undetectable		 1fbmD-4pq0A:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pxj C-JUN-AMINO-TERMINAL
KINASE-INTERACTING
PROTEIN 3

(Homo sapiens) 		PF16471
(JIP_LZII) 		4 THR A 433
LEU A 437
VAL A 440
LEU A 444
 None
 0.78A 1fbmD-4pxjA:
undetectable		 1fbmD-4pxjA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q65 DIPEPTIDE PERMEASE D

(Escherichia
coli) 		PF00854
(PTR2) 		4 THR A 463
LEU A 467
VAL A 470
LEU A 474
 None
 0.57A 1fbmD-4q65A:
undetectable		 1fbmD-4q65A:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rfs SUBSTRATE BINDING
PRITEIN S

(Lactobacillus
brevis) 		PF12822
(ECF_trnsprt) 		4 THR S 132
LEU S 136
VAL S 139
LEU S 164
 None
 0.87A 1fbmD-4rfsS:
undetectable		 1fbmD-4rfsS:
16.34