SIMILAR PATTERNS OF AMINO ACIDS FOR 1FBM_B_RTLB951_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b5l INTERFERON TAU

(Komagataella
pastoris) 		PF00143
(Interferon) 		4 THR A  79
LEU A  82
LEU A  89
GLN A  92
 None
 0.88A 1fbmA-1b5lA:
0.0		 1fbmA-1b5lA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bog ANTIBODY (CB 4-1)

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 THR B  87
LEU B  86
LEU B  20
GLN B   6
 None
 1.22A 1fbmA-1bogB:
undetectable		 1fbmA-1bogB:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cby DELTA-ENDOTOXIN CYTB

(Bacillus
thuringiensis) 		PF01338
(Bac_thur_toxin) 		4 THR A  95
LEU A 220
LEU A  60
GLN A  56
 None
 0.89A 1fbmA-1cbyA:
0.0		 1fbmA-1cbyA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gyt CYTOSOL
AMINOPEPTIDASE

(Escherichia
coli) 		PF00883
(Peptidase_M17)
PF02789
(Peptidase_M17_N) 		4 THR A 393
LEU A 395
LEU A 422
GLN A 427
 None
 1.23A 1fbmA-1gytA:
0.0		 1fbmA-1gytA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i3g ANTIBODY FV FRAGMENT

(Mus musculus) 		PF07686
(V-set) 		4 THR H  97
LEU H  96
LEU H  21
GLN H   6
 None
 1.22A 1fbmA-1i3gH:
undetectable		 1fbmA-1i3gH:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i8k EPIDERMAL GROWTH
FACTOR RECEPTOR
ANTIBODY MR1SCFV
LIGHT CHAIN
EPIDERMAL GROWTH
FACTOR RECEPTOR
ANTIBODY MR1SCFV
HEAVY CHAIN

(Mus musculus;
Mus musculus) 		PF07686
(V-set)
PF07686
(V-set) 		4 THR A  25
LEU A   4
LEU B 345
GLN B 339
 None
 1.25A 1fbmA-1i8kA:
undetectable		 1fbmA-1i8kA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iy2 ATP-DEPENDENT
METALLOPROTEASE FTSH

(Thermus
thermophilus) 		PF00004
(AAA) 		4 THR A 278
LEU A 279
LEU A 312
GLN A 320
 None
 1.23A 1fbmA-1iy2A:
0.0		 1fbmA-1iy2A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jnn MONOCLONAL
ANTI-ESTRADIOL
17E12E5
IMMUNOGLOBULIN
GAMMA-1 CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 THR H  87
LEU H  86
LEU H  20
GLN H   6
 None
 1.27A 1fbmA-1jnnH:
undetectable		 1fbmA-1jnnH:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1js4 ENDO/EXOCELLULASE E4

(Thermobifida
fusca) 		PF00759
(Glyco_hydro_9)
PF00942
(CBM_3) 		4 THR A 227
LEU A 223
LEU A 216
GLN A 213
 None
 1.15A 1fbmA-1js4A:
undetectable		 1fbmA-1js4A:
6.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lpe APOLIPOPROTEIN E3

(Homo sapiens) 		PF01442
(Apolipoprotein) 		4 THR A  67
LEU A  71
LEU A  78
GLN A  81
 None
 0.66A 1fbmA-1lpeA:
undetectable		 1fbmA-1lpeA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lq2 BETA-D-GLUCAN
GLUCOHYDROLASE
ISOENZYME EXO1

(Hordeum vulgare) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C) 		4 THR A 347
LEU A 350
LEU A 358
GLN A 141
 None
 1.22A 1fbmA-1lq2A:
undetectable		 1fbmA-1lq2A:
7.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nqb SINGLE-CHAIN
ANTIBODY FRAGMENT

(Mus musculus) 		PF07686
(V-set) 		4 THR A  87
LEU A  86
LEU A  20
GLN A   6
 None
 1.23A 1fbmA-1nqbA:
undetectable		 1fbmA-1nqbA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nrk YGFZ PROTEIN

(Escherichia
coli) 		PF01571
(GCV_T) 		4 THR A 278
LEU A 280
LEU A 190
GLN A 187
 None
 1.23A 1fbmA-1nrkA:
undetectable		 1fbmA-1nrkA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6a GENOME POLYPROTEIN

(Dengue virus) 		PF01728
(FtsJ) 		4 THR A 176
LEU A 143
LEU A 103
GLN A 127
 None
 0.96A 1fbmA-1r6aA:
undetectable		 1fbmA-1r6aA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wrb DJVLGB

(Dugesia
japonica) 		PF00270
(DEAD) 		4 THR A 235
LEU A 239
LEU A 246
GLN A 249
 SO4  A1001 (-3.8A)
None
None
None
 1.15A 1fbmA-1wrbA:
undetectable		 1fbmA-1wrbA:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wru 43 KDA TAIL PROTEIN

(Escherichia
virus Mu) 		PF05954
(Phage_GPD) 		4 THR A 299
LEU A 312
LEU A 271
GLN A 267
 None
 1.18A 1fbmA-1wruA:
undetectable		 1fbmA-1wruA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zkh SPLICING FACTOR 3
SUBUNIT 1

(Homo sapiens) 		PF00240
(ubiquitin) 		4 THR A  31
LEU A  67
LEU A  54
GLN A  52
 None
 1.12A 1fbmA-1zkhA:
undetectable		 1fbmA-1zkhA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c2y METHYLENETETRAHYDROF
OLATE
DEHYDROGENASE-METHEN
YLTETRAHYDROFOLATE
CYCLOHYDROLASE

(Mycobacterium
tuberculosis) 		PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C) 		4 THR A  75
LEU A  78
LEU A  39
GLN A  47
 None
 1.13A 1fbmA-2c2yA:
undetectable		 1fbmA-2c2yA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f6h MYOSIN-2

(Saccharomyces
cerevisiae) 		PF01843
(DIL) 		4 THR X 300
LEU X 299
LEU X 256
GLN X 184
 None
 0.96A 1fbmA-2f6hX:
undetectable		 1fbmA-2f6hX:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fmt METHIONYL-TRNA FMET
FORMYLTRANSFERASE

(Escherichia
coli) 		PF00551
(Formyl_trans_N)
PF02911
(Formyl_trans_C) 		4 THR A 163
LEU A 167
LEU A 174
GLN A 177
 None
 1.21A 1fbmA-2fmtA:
undetectable		 1fbmA-2fmtA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iel HYPOTHETICAL PROTEIN
TT0030

(Thermus
thermophilus) 		no annotation 4 THR A  11
LEU A  17
LEU A  24
GLN A  27
 None
 1.22A 1fbmA-2ielA:
undetectable		 1fbmA-2ielA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jii SERINE/THREONINE-PRO
TEIN KINASE VRK3
MOLECULE: VACCINIA
RELATED KINASE 3

(Homo sapiens) 		PF00069
(Pkinase) 		4 THR A 173
LEU A 180
LEU A 257
GLN A 215
 None
 1.26A 1fbmA-2jiiA:
undetectable		 1fbmA-2jiiA:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kc3 APOLIPOPROTEIN E

(Homo sapiens) 		PF01442
(Apolipoprotein) 		4 THR A  67
LEU A  71
LEU A  78
GLN A  81
 None
 1.18A 1fbmA-2kc3A:
undetectable		 1fbmA-2kc3A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l7b APOLIPOPROTEIN E

(Homo sapiens) 		PF01442
(Apolipoprotein) 		4 THR A  67
LEU A  71
LEU A  78
GLN A  81
 None
 1.24A 1fbmA-2l7bA:
undetectable		 1fbmA-2l7bA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m0m MINOR AMPULLATE
FIBROIN 1

(Nephila
antipodiana) 		PF11260
(Spidroin_MaSp) 		4 THR A  52
LEU A  55
LEU A  62
GLN A  65
 None
 1.04A 1fbmA-2m0mA:
undetectable		 1fbmA-2m0mA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o3b NUCLEASE

(Nostoc sp. PCC
7120) 		PF01223
(Endonuclease_NS) 		4 THR A 158
LEU A 162
LEU A 169
GLN A 172
 None
 0.89A 1fbmA-2o3bA:
undetectable		 1fbmA-2o3bA:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2op4 MURINE ANTIBODY FAB
RS2-1G9 IGG1 HEAVY
CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 THR H  83
LEU H  82
LEU H  20
GLN H   6
 None
 1.17A 1fbmA-2op4H:
undetectable		 1fbmA-2op4H:
7.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r5j MAJOR CAPSID PROTEIN
L1

(Alphapapillomavirus
9) 		PF00500
(Late_protein_L1) 		4 THR A 154
LEU A 156
LEU A 246
GLN A 315
 None
 1.06A 1fbmA-2r5jA:
undetectable		 1fbmA-2r5jA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rci TYPE-2BA CYTOLYTIC
DELTA-ENDOTOXIN

(Bacillus
thuringiensis) 		PF01338
(Bac_thur_toxin) 		4 THR A  95
LEU A 220
LEU A  60
GLN A  56
 THR  A  95 ( 0.8A)
LEU  A 220 ( 0.6A)
LEU  A  60 ( 0.5A)
GLN  A  56 ( 0.6A)
 0.74A 1fbmA-2rciA:
undetectable		 1fbmA-2rciA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w3z PUTATIVE DEACETYLASE

(Streptococcus
mutans) 		PF01522
(Polysacc_deac_1) 		4 THR A 220
LEU A 222
LEU A 229
GLN A 232
 None
 1.13A 1fbmA-2w3zA:
undetectable		 1fbmA-2w3zA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wan PULLULANASE

(Bacillus
acidopullulyticus) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		4 THR A 352
LEU A 343
LEU A 367
GLN A 358
 None
 1.13A 1fbmA-2wanA:
undetectable		 1fbmA-2wanA:
4.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wyh ALPHA-MANNOSIDASE

(Streptococcus
pyogenes) 		PF01074
(Glyco_hydro_38)
PF07748
(Glyco_hydro_38C)
PF09261
(Alpha-mann_mid) 		4 THR A 611
LEU A 648
LEU A 780
GLN A 306
 None
 1.23A 1fbmA-2wyhA:
undetectable		 1fbmA-2wyhA:
5.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yhe SEC-ALKYL SULFATASE

(Pseudomonas sp.
DSM 6611) 		PF00753
(Lactamase_B)
PF14863
(Alkyl_sulf_dimr)
PF14864
(Alkyl_sulf_C) 		4 THR A 151
LEU A 150
LEU A 162
GLN A 165
 None
 1.14A 1fbmA-2yheA:
undetectable		 1fbmA-2yheA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a3j PBP5

(Haemophilus
influenzae) 		PF00768
(Peptidase_S11)
PF07943
(PBP5_C) 		4 THR A 287
LEU A 288
LEU A 309
GLN A 297
 None
 1.16A 1fbmA-3a3jA:
undetectable		 1fbmA-3a3jA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aqc COMPONENT B OF
HEXAPRENYL
DIPHOSPHATE SYNTHASE

(Micrococcus
luteus) 		PF00348
(polyprenyl_synt) 		4 THR B 237
LEU B 240
LEU B 247
GLN B 250
 None
 0.74A 1fbmA-3aqcB:
undetectable		 1fbmA-3aqcB:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3crc PROTEIN MAZG

(Escherichia
coli) 		PF03819
(MazG) 		4 THR A 201
LEU A 197
LEU A 190
GLN A 187
 None
 0.88A 1fbmA-3crcA:
undetectable		 1fbmA-3crcA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e2v 3'-5'-EXONUCLEASE

(Saccharomyces
cerevisiae) 		PF01026
(TatD_DNase) 		4 THR A 408
LEU A 322
LEU A 286
GLN A 287
 None
 1.21A 1fbmA-3e2vA:
undetectable		 1fbmA-3e2vA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e6e ALANINE RACEMASE

(Enterococcus
faecalis) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 THR A 120
LEU A 119
LEU A 112
GLN A 109
 None
 1.14A 1fbmA-3e6eA:
undetectable		 1fbmA-3e6eA:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eh2 PROTEIN TRANSPORT
PROTEIN SEC24C

(Homo sapiens) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		4 THR A 628
LEU A 627
LEU A 712
GLN A 715
 None
 1.10A 1fbmA-3eh2A:
undetectable		 1fbmA-3eh2A:
5.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fxi TOLL-LIKE RECEPTOR 4

(Homo sapiens) 		PF13516
(LRR_6)
PF13855
(LRR_8) 		4 THR A 577
LEU A 576
LEU A 564
GLN A 562
 NAG  A 761 (-3.8A)
None
None
None
 1.20A 1fbmA-3fxiA:
undetectable		 1fbmA-3fxiA:
5.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g87 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE

(Burkholderia
pseudomallei) 		PF00698
(Acyl_transf_1) 		4 THR A 109
LEU A 113
LEU A 120
GLN A 123
 None
 0.85A 1fbmA-3g87A:
undetectable		 1fbmA-3g87A:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdc MULTICOPPER OXIDASE

(Arthrobacter
sp. FB24) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 THR A  25
LEU A  28
LEU A 220
GLN A 259
 None
 1.13A 1fbmA-3gdcA:
undetectable		 1fbmA-3gdcA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hxt 5-FORMYLTETRAHYDROFO
LATE CYCLO-LIGASE

(Homo sapiens) 		PF01812
(5-FTHF_cyc-lig) 		4 THR A 170
LEU A 171
LEU A  36
GLN A  32
 None
 1.19A 1fbmA-3hxtA:
undetectable		 1fbmA-3hxtA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i3w PHOSPHOGLUCOSAMINE
MUTASE

(Francisella
tularensis) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 THR A  24
LEU A  27
LEU A  34
GLN A  37
 None
 1.25A 1fbmA-3i3wA:
undetectable		 1fbmA-3i3wA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j8w H263.A2 HEAVY CHAIN

(Mus musculus) 		no annotation 4 THR H  83
LEU H  82
LEU H  20
GLN H   6
 None
 1.24A 1fbmA-3j8wH:
undetectable		 1fbmA-3j8wH:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l40 BRCT-CONTAINING
PROTEIN 1

(Schizosaccharomyces
pombe) 		PF16770
(RTT107_BRCT_5) 		4 THR A 708
LEU A 712
LEU A 771
GLN A 767
 None
 1.13A 1fbmA-3l40A:
undetectable		 1fbmA-3l40A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ln6 GLUTATHIONE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
GSHAB

(Streptococcus
agalactiae) 		PF01071
(GARS_A)
PF04262
(Glu_cys_ligase) 		4 THR A 384
LEU A 191
LEU A 371
GLN A 368
 None
 1.23A 1fbmA-3ln6A:
undetectable		 1fbmA-3ln6A:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lso PUTATIVE MEMBRANE
ANCHORED PROTEIN

(Corynebacterium
diphtheriae) 		PF16640
(Big_3_5) 		4 THR B 168
LEU B 167
LEU B 124
GLN B 128
 None
 1.15A 1fbmA-3lsoB:
undetectable		 1fbmA-3lsoB:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m49 TRANSKETOLASE

(Bacillus
anthracis) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 THR A 430
LEU A 428
LEU A 330
GLN A 331
 None
 1.24A 1fbmA-3m49A:
undetectable		 1fbmA-3m49A:
5.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3npe 9-CIS-EPOXYCAROTENOI
D DIOXYGENASE 1,
CHLOROPLASTIC

(Zea mays) 		PF03055
(RPE65) 		4 THR A 490
LEU A 512
LEU A 468
GLN A 472
 None
 1.26A 1fbmA-3npeA:
undetectable		 1fbmA-3npeA:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1

(Anopheles
gambiae) 		PF13855
(LRR_8) 		4 THR B 666
LEU B 669
LEU B 676
GLN B 679
 None
 1.25A 1fbmA-3ojaB:
3.5		 1fbmA-3ojaB:
5.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oja LEUCINE-RICH IMMUNE
MOLECULE 1

(Anopheles
gambiae) 		PF00560
(LRR_1) 		4 THR A 493
LEU A 497
LEU A 504
GLN A 507
 None
 0.62A 1fbmA-3ojaA:
4.2		 1fbmA-3ojaA:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qbd 3-DEHYDROQUINATE
SYNTHASE

(Mycobacterium
tuberculosis) 		PF01761
(DHQ_synthase) 		4 THR A 171
LEU A 172
LEU A 210
GLN A 207
 NAD  A 400 (-4.9A)
None
None
None
 1.22A 1fbmA-3qbdA:
undetectable		 1fbmA-3qbdA:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r8b G5-8

(Rattus
norvegicus) 		PF07686
(V-set) 		4 THR B  98
LEU B  99
LEU B  43
GLN B  37
 None
 1.21A 1fbmA-3r8bB:
undetectable		 1fbmA-3r8bB:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s88 ENVELOPE
GLYCOPROTEIN

(Sudan
ebolavirus) 		no annotation 4 THR J 565
LEU J 561
LEU J 554
GLN J 551
 None
 1.07A 1fbmA-3s88J:
undetectable		 1fbmA-3s88J:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uzv ANTI-DENGUE MAB 4E11

(Mus musculus) 		PF07686
(V-set) 		4 THR B  88
LEU B  87
LEU B  21
GLN B   7
 None
 1.16A 1fbmA-3uzvB:
undetectable		 1fbmA-3uzvB:
11.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3v2p CARTILAGE
OLIGOMERIZATION
MATRIX PROTEIN
(COILED-COIL DOMAIN)

(Mus musculus) 		PF11598
(COMP) 		4 THR A  40
LEU A  44
LEU A  51
GLN A  54
 STE  A   1 (-4.0A)
STE  A   1 ( 4.5A)
STE  A   1 (-4.4A)
STE  A   1 (-3.4A)
 0.45A 1fbmA-3v2pA:
5.6		 1fbmA-3v2pA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vhj BFPC

(Escherichia
coli) 		no annotation 4 THR A  40
LEU A  39
LEU A 161
GLN A  71
 None
 1.11A 1fbmA-3vhjA:
undetectable		 1fbmA-3vhjA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vx4 PUTATIVE ABC
TRANSPORTER,
ATP-BINDING PROTEIN
COMA

(Streptococcus
mutans) 		PF00005
(ABC_tran) 		4 THR A 543
LEU A 544
LEU A 549
GLN A 742
 ATP  A 801 (-3.8A)
None
None
None
 1.16A 1fbmA-3vx4A:
undetectable		 1fbmA-3vx4A:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wsv L-LACTATE
DEHYDROGENASE

(Enterococcus
mundtii) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 THR A 129
LEU A 128
LEU A  94
GLN A  85
 None
 1.14A 1fbmA-3wsvA:
undetectable		 1fbmA-3wsvA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF16739
(CARD_2) 		4 THR A 176
LEU A 173
LEU A 184
GLN A 518
 None
 1.21A 1fbmA-4a2qA:
undetectable		 1fbmA-4a2qA:
4.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ars HISTIDINE ACID
PHOSPHATASE

(Hafnia alvei) 		PF00328
(His_Phos_2) 		4 THR A  35
LEU A 172
LEU A 165
GLN A 162
 None
 1.23A 1fbmA-4arsA:
undetectable		 1fbmA-4arsA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190

(Saccharomyces
cerevisiae) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 THR A1623
LEU A1627
LEU A 335
GLN A 332
 None
 1.14A 1fbmA-4c3hA:
2.5		 1fbmA-4c3hA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eog PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pyrococcus
furiosus) 		PF09455
(Cas_DxTHG) 		4 THR A 176
LEU A 180
LEU A 159
GLN A 156
 None
 1.15A 1fbmA-4eogA:
undetectable		 1fbmA-4eogA:
6.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4etn LOW MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YWLE

(Bacillus
subtilis) 		PF01451
(LMWPc) 		4 THR A 130
LEU A 134
LEU A 141
GLN A 144
 None
 0.93A 1fbmA-4etnA:
undetectable		 1fbmA-4etnA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ffz DENV1-E111 FAB
FRAGMENT (HEAVY
CHAIN)

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 THR H  83
LEU H  82
LEU H  20
GLN H   6
 None
 1.23A 1fbmA-4ffzH:
undetectable		 1fbmA-4ffzH:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fhn NUCLEOPORIN NUP120

(Schizosaccharomyces
pombe) 		PF11715
(Nup160) 		4 THR B 938
LEU B 942
LEU B 978
GLN B 981
 None
 0.89A 1fbmA-4fhnB:
undetectable		 1fbmA-4fhnB:
3.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gkf CRISPR SYSTEM CMR
SUBUNIT CMR5

(Pyrococcus
furiosus) 		PF09701
(Cas_Cmr5) 		4 THR A  74
LEU A  69
LEU A 128
GLN A 131
 None
 1.00A 1fbmA-4gkfA:
undetectable		 1fbmA-4gkfA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k1p NHEA

(Bacillus cereus) 		PF05791
(Bacillus_HBL) 		4 THR A  20
LEU A  21
LEU A  28
GLN A  31
 None
 1.14A 1fbmA-4k1pA:
undetectable		 1fbmA-4k1pA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lxr PROTEIN TOLL

(Drosophila
melanogaster) 		PF00560
(LRR_1)
PF01462
(LRRNT)
PF13306
(LRR_5)
PF13855
(LRR_8) 		4 THR A 437
LEU A 416
LEU A 368
GLN A 365
 None
 1.00A 1fbmA-4lxrA:
undetectable		 1fbmA-4lxrA:
5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mif PYRANOSE 2-OXIDASE

(Phanerochaete
chrysosporium) 		PF05199
(GMC_oxred_C) 		4 THR A 600
LEU A 599
LEU A 242
GLN A 440
 None
 1.26A 1fbmA-4mifA:
undetectable		 1fbmA-4mifA:
5.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ng3 5-CARBOXYVANILLATE
DECARBOXYLASE

(Sphingomonas
paucimobilis) 		PF04909
(Amidohydro_2) 		4 THR A  87
LEU A  91
LEU A  98
GLN A 101
 None
 0.59A 1fbmA-4ng3A:
undetectable		 1fbmA-4ng3A:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nnd TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 18

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 THR A 236
LEU A 239
LEU A 208
GLN A 290
 None
 1.25A 1fbmA-4nndA:
undetectable		 1fbmA-4nndA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nzm INOSITOL
HEXAKISPHOSPHATE AND
DIPHOSPHOINOSITOL-PE
NTAKISPHOSPHATE
KINASE 2

(Homo sapiens) 		no annotation 4 THR A 242
LEU A 311
LEU A 148
GLN A 142
 None
ANP  A 401 (-4.7A)
None
None
 1.14A 1fbmA-4nzmA:
undetectable		 1fbmA-4nzmA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rfs SUBSTRATE BINDING
PRITEIN S

(Lactobacillus
brevis) 		PF12822
(ECF_trnsprt) 		4 THR S 130
LEU S 134
LEU S 141
GLN S 144
 None
 1.05A 1fbmA-4rfsS:
undetectable		 1fbmA-4rfsS:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rh7 GREEN FLUORESCENT
PROTEIN/CYTOPLASMIC
DYNEIN 2 HEAVY CHAIN
1

(Homo sapiens;
synthetic
construct) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		4 THR A3395
LEU A3399
LEU A3406
GLN A3409
 None
 1.22A 1fbmA-4rh7A:
undetectable		 1fbmA-4rh7A:
1.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rkc AROMATIC AMINO ACID
AMINOTRANSFERASE

(Psychrobacter
sp. B6) 		PF00155
(Aminotran_1_2) 		4 THR A 342
LEU A 341
LEU A 353
GLN A 357
 None
 1.10A 1fbmA-4rkcA:
undetectable		 1fbmA-4rkcA:
7.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wz9 AGAP004809-PA

(Anopheles
gambiae) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		4 THR A 291
LEU A 294
LEU A 319
GLN A 371
 None
 1.27A 1fbmA-4wz9A:
undetectable		 1fbmA-4wz9A:
3.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wzi CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B

(Homo sapiens) 		PF00233
(PDEase_I) 		4 THR A 222
LEU A 226
LEU A 233
GLN A 237
 None
 1.20A 1fbmA-4wziA:
undetectable		 1fbmA-4wziA:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y1k OUTER MEMBRANE
PROTEIN OPRM

(Pseudomonas
aeruginosa) 		PF02321
(OEP) 		4 THR A 156
LEU A 157
LEU A  52
GLN A  48
 None
 1.17A 1fbmA-4y1kA:
undetectable		 1fbmA-4y1kA:
6.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c3l NUCLEOPORIN NUP58

(Xenopus laevis) 		PF15967
(Nucleoporin_FG2) 		4 THR B 349
LEU B 353
LEU B 360
GLN B 363
 None
 0.85A 1fbmA-5c3lB:
undetectable		 1fbmA-5c3lB:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c65 SOLUTE CARRIER
FAMILY 2,
FACILITATED GLUCOSE
TRANSPORTER MEMBER 3

(Homo sapiens) 		PF00083
(Sugar_tr) 		4 THR A 156
LEU A 160
LEU A 167
GLN A 170
 None
 1.03A 1fbmA-5c65A:
undetectable		 1fbmA-5c65A:
7.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d28 GRANULOCYTE-MACROPHA
GE
COLONY-STIMULATING
FACTOR

(Ovis aries) 		PF01109
(GM_CSF) 		4 THR B  71
LEU B  66
LEU B  59
GLN B  56
 None
 1.26A 1fbmA-5d28B:
undetectable		 1fbmA-5d28B:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dn7 PROTEIN FAM179B

(Mus musculus) 		no annotation 4 THR A 413
LEU A 417
LEU A 424
GLN A 427
 None
 1.07A 1fbmA-5dn7A:
undetectable		 1fbmA-5dn7A:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dol INITIATION-CONTROL
PROTEIN YABA

(Bacillus
subtilis) 		PF06156
(YabB) 		4 THR A   9
LEU A  13
LEU A  20
GLN A  23
 None
 0.74A 1fbmA-5dolA:
undetectable		 1fbmA-5dolA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e84 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo sapiens) 		PF00012
(HSP70) 		4 THR A 557
LEU A 561
LEU A 568
GLN A 571
 None
 1.16A 1fbmA-5e84A:
undetectable		 1fbmA-5e84A:
5.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fq6 PUTATIVE LIPOPROTEIN

(Bacteroides
thetaiotaomicron) 		PF12771
(SusD-like_2) 		4 THR A 209
LEU A 210
LEU A 325
GLN A 322
 None
 1.06A 1fbmA-5fq6A:
undetectable		 1fbmA-5fq6A:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5htl MSHA BIOGENESIS
PROTEIN MSHE

(Vibrio cholerae) 		PF05157
(T2SSE_N) 		4 THR A  42
LEU A  39
LEU A  13
GLN A  60
 None
C2E  A 201 (-4.3A)
None
None
 1.26A 1fbmA-5htlA:
undetectable		 1fbmA-5htlA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5huo NICOTINATE-NUCLEOTID
E DIPHOSPHORYLASE
(CARBOXYLATING)

(Streptococcus
pyogenes) 		PF01729
(QRPTase_C)
PF02749
(QRPTase_N) 		4 THR A  85
LEU A  84
LEU A  57
GLN A  61
 None
 1.21A 1fbmA-5huoA:
undetectable		 1fbmA-5huoA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5huu ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
[UDP-FORMING]

(Candida
albicans) 		PF00982
(Glyco_transf_20) 		4 THR A 434
LEU A 433
LEU A 310
GLN A 312
 None
 1.13A 1fbmA-5huuA:
undetectable		 1fbmA-5huuA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i7m DNA PRIMASE LARGE
SUBUNIT

(Homo sapiens) 		PF04104
(DNA_primase_lrg) 		4 THR A 363
LEU A 311
LEU A 291
GLN A 290
 None
 1.17A 1fbmA-5i7mA:
undetectable		 1fbmA-5i7mA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nqs PROTEIN TOPLESS

(Arabidopsis
thaliana) 		no annotation 4 THR A 165
LEU A 166
LEU A 174
GLN A 177
 None
 1.07A 1fbmA-5nqsA:
undetectable		 1fbmA-5nqsA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t33 RHPA GP120 CORE

(Human
immunodeficiency
virus) 		PF00516
(GP120) 		4 THR G 455
LEU G 454
LEU G 342
GLN G 339
 None
 1.09A 1fbmA-5t33G:
undetectable		 1fbmA-5t33G:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5voc ENVELOPE
GLYCOPROTEIN H

(Human
betaherpesvirus
5) 		PF02489
(Herpes_glycop_H)
PF17488
(Herpes_glycoH_C) 		4 THR A 453
LEU A 450
LEU A 469
GLN A 375
 None
 1.18A 1fbmA-5vocA:
undetectable		 1fbmA-5vocA:
5.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x6o SERINE/THREONINE-PRO
TEIN KINASE MEC1

(Saccharomyces
cerevisiae) 		no annotation 4 THR C 635
LEU C 647
LEU C 691
GLN C 694
 None
 1.18A 1fbmA-5x6oC:
undetectable		 1fbmA-5x6oC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xun ACETYLTRANSFERASE

(Klebsiella
pneumoniae) 		PF13673
(Acetyltransf_10) 		4 THR A  64
LEU A  94
LEU A 161
GLN A 152
 None
 1.12A 1fbmA-5xunA:
undetectable		 1fbmA-5xunA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ywz SUN
DOMAIN-CONTAINING
PROTEIN 1

(Mus musculus) 		no annotation 4 THR A 828
LEU A 829
LEU A 777
GLN A 677
 None
 1.25A 1fbmA-5ywzA:
undetectable		 1fbmA-5ywzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6en4 SPLICING FACTOR 3B
SUBUNIT 3

(Homo sapiens) 		no annotation 4 THR A 677
LEU A 665
LEU A 592
GLN A 553
 None
 0.94A 1fbmA-6en4A:
undetectable		 1fbmA-6en4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1

(Homo sapiens) 		no annotation 4 THR A 321
LEU A 322
LEU A 269
GLN A 207
 None
 1.03A 1fbmA-6f9nA:
undetectable		 1fbmA-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2

(Mus musculus) 		no annotation 4 THR N 201
LEU N 194
LEU N 148
GLN N  88
 None
 1.07A 1fbmA-6g72N:
undetectable		 1fbmA-6g72N:
undetectable