SIMILAR PATTERNS OF AMINO ACIDS FOR 1F9G_A_ASCA950

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bhg BETA-GLUCURONIDASE

(Homo sapiens) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		4 ARG A 382
TRP A 587
TYR A 508
ARG A 600
 None
 1.48A 1f9gA-1bhgA:
0.5		 1f9gA-1bhgA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cb8 PROTEIN
(CHONDROITINASE AC)

(Pedobacter
heparinus) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		6 ASN A 125
TRP A 127
TYR A 234
ARG A 288
ARG A 292
ASN A 374
 None
None
GOL  A2010 (-3.9A)
GOL  A2010 ( 3.7A)
GOL  A2010 ( 2.6A)
None
 0.46A 1f9gA-1cb8A:
43.6		 1f9gA-1cb8A:
26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gfn MATRIX PORIN OUTER
MEMBRANE PROTEIN F

(Escherichia
coli) 		PF00267
(Porin_1) 		4 ARG A 167
ARG A  82
ARG A 132
ASN A  64
 None
 1.38A 1f9gA-1gfnA:
4.6		 1f9gA-1gfnA:
21.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1i8q HYALURONATE LYASE

(Streptococcus
agalactiae) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		4 ARG A 321
TYR A 488
ARG A 542
ASN A 660
 GC4  A1001 (-3.2A)
None
NAG  A1002 (-4.6A)
None
 0.90A 1f9gA-1i8qA:
55.1		 1f9gA-1i8qA:
53.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1i8q HYALURONATE LYASE

(Streptococcus
agalactiae) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		4 TYR A 484
ARG A 542
ARG A 546
ASN A 660
 None
NAG  A1002 (-4.6A)
NAG  A1002 (-3.3A)
None
 1.02A 1f9gA-1i8qA:
55.1		 1f9gA-1i8qA:
53.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1i8q HYALURONATE LYASE

(Streptococcus
agalactiae) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		4 TYR A 488
ARG A 542
ARG A 546
ASN A 660
 None
NAG  A1002 (-4.6A)
NAG  A1002 (-3.3A)
None
 0.41A 1f9gA-1i8qA:
55.1		 1f9gA-1i8qA:
53.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1j0n XANTHAN LYASE

(Bacillus sp.
GL1) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		6 ASN A 146
TRP A 148
TYR A 255
ARG A 309
ARG A 313
ASN A 424
 None
CEG  A 780 (-3.6A)
CEG  A 780 (-4.4A)
CEG  A 780 (-3.6A)
CEG  A 780 (-2.9A)
None
 0.74A 1f9gA-1j0nA:
47.8		 1f9gA-1j0nA:
30.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j1w ISOCITRATE
DEHYDROGENASE

(Azotobacter
vinelandii) 		PF03971
(IDH) 		4 ASN A  85
TYR A 420
ARG A 139
ARG A 145
 NAP  A1000 (-4.0A)
None
NAP  A1000 ( 4.6A)
None
 1.30A 1f9gA-1j1wA:
undetectable		 1f9gA-1j1wA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l5x SURVIVAL PROTEIN E

(Pyrobaculum
aerophilum) 		PF01975
(SurE) 		4 ARG A 174
ASN A  93
TYR A 192
ASN A  97
 ACY  A 402 (-4.8A)
None
None
None
 1.29A 1f9gA-1l5xA:
undetectable		 1f9gA-1l5xA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mkx PRETHROMBIN-2

(Bos taurus) 		PF00089
(Trypsin)
PF09396
(Thrombin_light) 		4 ARG K 233
ASN K  98
ARG K  93
ASN K  95
 None
 0.98A 1f9gA-1mkxK:
undetectable		 1f9gA-1mkxK:
17.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1n7r HYALURONIDASE

(Streptococcus
pneumoniae) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		6 ARG A 243
ASN A 290
TYR A 408
ARG A 462
ARG A 466
ASN A 580
 BDP  A1003 ( 2.3A)
BDP  A1001 ( 3.8A)
NAG  A1002 ( 2.6A)
BDP  A1001 ( 3.1A)
NAG  A1002 (-3.4A)
BDP  A1001 ( 2.4A)
 0.74A 1f9gA-1n7rA:
65.1		 1f9gA-1n7rA:
99.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1n7r HYALURONIDASE

(Streptococcus
pneumoniae) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		4 TYR A 404
ARG A 462
ARG A 466
ASN A 580
 None
BDP  A1001 ( 3.1A)
NAG  A1002 (-3.4A)
BDP  A1001 ( 2.4A)
 1.03A 1f9gA-1n7rA:
65.1		 1f9gA-1n7rA:
99.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qsa PROTEIN (SOLUBLE
LYTIC
TRANSGLYCOSYLASE
SLT70)

(Escherichia
coli) 		PF01464
(SLT)
PF14718
(SLT_L) 		4 ARG A 261
ASN A 265
ARG A 558
ASN A 565
 None
 1.50A 1f9gA-1qsaA:
2.7		 1f9gA-1qsaA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rw9 CHONDROITIN AC LYASE

(Paenarthrobacter
aurescens) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		5 ARG A 134
ASN A 124
ARG A 296
ARG A 300
ASN A 410
 None
None
PO4  A 850 ( 4.2A)
None
None
 1.26A 1f9gA-1rw9A:
45.5		 1f9gA-1rw9A:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rw9 CHONDROITIN AC LYASE

(Paenarthrobacter
aurescens) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		4 ARG A 134
TYR A 238
ARG A 296
ARG A 300
 None
None
PO4  A 850 ( 4.2A)
None
 1.15A 1f9gA-1rw9A:
45.5		 1f9gA-1rw9A:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rw9 CHONDROITIN AC LYASE

(Paenarthrobacter
aurescens) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		6 ASN A 124
TRP A 126
TYR A 242
ARG A 296
ARG A 300
ASN A 410
 None
PO4  A 850 (-4.7A)
PO4  A 850 (-4.8A)
PO4  A 850 ( 4.2A)
None
None
 0.55A 1f9gA-1rw9A:
45.5		 1f9gA-1rw9A:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1si1 IRON BINDING PROTEIN
FBPA

(Mannheimia
haemolytica) 		PF13343
(SBP_bac_6) 		4 TYR A 199
ARG A 136
ARG A 103
ASN A 140
 FE  A 321 (-4.0A)
None
None
None
 1.45A 1f9gA-1si1A:
undetectable		 1f9gA-1si1A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dbr GLYOXYLATE REDUCTASE

(Pyrococcus
horikoshii) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 ARG A 160
ASN A  73
ARG A 241
ASN A  80
 SO4  A 501 ( 2.7A)
None
SO4  A 507 ( 3.1A)
None
 1.48A 1f9gA-2dbrA:
undetectable		 1f9gA-2dbrA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j63 AP-ENDONUCLEASE

(Leishmania
major) 		PF03372
(Exo_endo_phos) 		4 ARG A 398
ASN A 337
TYR A 200
ARG A 286
 None
 1.43A 1f9gA-2j63A:
undetectable		 1f9gA-2j63A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q27 OXALYL-COA
DECARBOXYLASE

(Escherichia
coli) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 ASN A  91
TRP A 420
ARG A 158
ASN A  95
 None
 1.46A 1f9gA-2q27A:
undetectable		 1f9gA-2q27A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rjo TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Paraburkholderia
phytofirmans) 		PF13407
(Peripla_BP_4) 		4 ASN A 131
TRP A 130
TYR A  55
ARG A  48
 GAL  A 368 (-3.7A)
GAL  A 368 ( 4.0A)
SO4  A 370 ( 4.2A)
GAL  A 368 ( 3.0A)
 1.25A 1f9gA-2rjoA:
undetectable		 1f9gA-2rjoA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rjo TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Paraburkholderia
phytofirmans) 		PF13407
(Peripla_BP_4) 		4 ASN A 131
TRP A 130
TYR A  55
ASN A 183
 GAL  A 368 (-3.7A)
GAL  A 368 ( 4.0A)
SO4  A 370 ( 4.2A)
GAL  A 368 (-4.3A)
 1.47A 1f9gA-2rjoA:
undetectable		 1f9gA-2rjoA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wda PUTATIVE SECRETED
LYASE

(Streptomyces
violaceoruber) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		5 ARG A 149
ASN A 139
ARG A 307
ARG A 311
ASN A 432
 PEG  A1775 ( 2.9A)
GOL  A1773 (-2.8A)
L42  A1784 (-3.4A)
L42  A1784 (-2.8A)
GOL  A1773 (-3.7A)
 1.34A 1f9gA-2wdaA:
43.4		 1f9gA-2wdaA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wda PUTATIVE SECRETED
LYASE

(Streptomyces
violaceoruber) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		4 ARG A 149
TYR A 249
ARG A 307
ARG A 311
 PEG  A1775 ( 2.9A)
None
L42  A1784 (-3.4A)
L42  A1784 (-2.8A)
 1.17A 1f9gA-2wdaA:
43.4		 1f9gA-2wdaA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wda PUTATIVE SECRETED
LYASE

(Streptomyces
violaceoruber) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		6 ASN A 139
TRP A 141
TYR A 253
ARG A 307
ARG A 311
ASN A 432
 GOL  A1773 (-2.8A)
L42  A1784 (-3.8A)
L42  A1784 ( 3.4A)
L42  A1784 (-3.4A)
L42  A1784 (-2.8A)
GOL  A1773 (-3.7A)
 0.51A 1f9gA-2wdaA:
43.4		 1f9gA-2wdaA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yk6 CMP-N-ACETYLNEURAMIN
ATE-BETA-GALACTOSAMI
DE-ALPHA-2,3-SIALYLT
RANSFERASE

(Neisseria
meningitidis) 		PF07922
(Glyco_transf_52) 		4 ARG A 226
ASN A 220
TYR A 176
ASN A 169
 None
 1.42A 1f9gA-2yk6A:
undetectable		 1f9gA-2yk6A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ckz NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		4 ARG A 152
ASN A 294
ARG A 371
ARG A 118
 ZMR  A 469 (-3.9A)
ZMR  A 469 (-3.9A)
ZMR  A 469 (-2.9A)
ZMR  A 469 (-2.9A)
 1.44A 1f9gA-3ckzA:
undetectable		 1f9gA-3ckzA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE

(Streptococcus
pneumoniae) 		PF12905
(Glyco_hydro_101)
PF17451
(Glyco_hyd_101C) 		4 ARG A1043
TYR A 889
ARG A 955
ASN A 953
 None
 1.38A 1f9gA-3ecqA:
5.9		 1f9gA-3ecqA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k7x LIN0763 PROTEIN

(Listeria
innocua) 		PF03663
(Glyco_hydro_76) 		4 ARG A 273
ASN A  97
TYR A 324
ASN A  78
 None
 1.18A 1f9gA-3k7xA:
6.3		 1f9gA-3k7xA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron) 		PF01494
(FAD_binding_3) 		4 ARG A 302
ASN A 352
TYR A 360
ASN A 337
 None
 1.49A 1f9gA-3p9uA:
undetectable		 1f9gA-3p9uA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ti8 NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		4 ARG A 152
ASN A 294
ARG A 371
ARG A 118
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-3.0A)
 1.45A 1f9gA-3ti8A:
undetectable		 1f9gA-3ti8A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a4z ANTIVIRAL HELICASE
SKI2

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF08148
(DSHCT)
PF13234
(rRNA_proc-arch) 		4 ARG A1095
ASN A 813
ARG A 454
ASN A1122
 None
 1.46A 1f9gA-4a4zA:
2.9		 1f9gA-4a4zA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4agv GALECTIN

(Cinachyrella) 		PF00337
(Gal-bind_lectin) 		4 ASN A  60
TRP A  68
ARG A  47
ARG A  28
 None
 1.39A 1f9gA-4agvA:
undetectable		 1f9gA-4agvA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b7j NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		4 ARG A 152
ASN A 295
ARG A 368
ARG A 118
 G39  A1470 (-3.9A)
G39  A1470 ( 3.7A)
G39  A1470 (-3.0A)
G39  A1470 (-3.1A)
 1.40A 1f9gA-4b7jA:
undetectable		 1f9gA-4b7jA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cpn NEURAMINIDASE

(Influenza B
virus) 		PF00064
(Neur) 		4 ARG A 149
ASN A 293
ARG A 373
ARG A 115
 ZMR  A 700 (-4.0A)
ZMR  A 700 ( 3.9A)
ZMR  A 700 (-3.0A)
ZMR  A 700 (-2.9A)
 1.44A 1f9gA-4cpnA:
undetectable		 1f9gA-4cpnA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iug BETA-GALACTOSIDASE A

(Aspergillus
oryzae) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		4 ARG A  71
ASN A 199
TYR A 260
ASN A 235
 None
GAL  A1130 (-3.5A)
GAL  A1130 (-4.5A)
GAL  A1130 (-4.6A)
 1.50A 1f9gA-4iugA:
undetectable		 1f9gA-4iugA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jhz BETA-GLUCURONIDASE

(Escherichia
coli) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		4 ARG A 327
TYR A 472
ARG A 562
ASN A 566
 None
1KV  A 701 (-3.8A)
1KV  A 701 (-4.0A)
None
 1.12A 1f9gA-4jhzA:
undetectable		 1f9gA-4jhzA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jkl BETA-GLUCURONIDASE

(Streptococcus
agalactiae) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		4 ARG A 326
TYR A 468
ARG A 559
ASN A 563
 None
 1.19A 1f9gA-4jklA:
undetectable		 1f9gA-4jklA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jkm BETA-GLUCURONIDASE

(Clostridium
perfringens) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		4 ARG A 329
TYR A 472
ARG A 563
ASN A 567
 None
 1.20A 1f9gA-4jkmA:
undetectable		 1f9gA-4jkmA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b04 PROBABLE TRANSLATION
INITIATION FACTOR
EIF-2B SUBUNIT
EPSILON

(Schizosaccharomyces
pombe) 		PF00132
(Hexapep)
PF00483
(NTP_transferase) 		4 ASN I 216
ARG I 171
ARG I 194
ASN I 192
 None
 1.34A 1f9gA-5b04I:
undetectable		 1f9gA-5b04I:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3

(Arabidopsis
thaliana) 		PF00311
(PEPcase) 		4 ARG A 690
ASN A 966
ARG A 891
ARG A 887
 None
ASP  A1001 (-3.0A)
ASP  A1001 (-2.9A)
ASP  A1001 ( 3.8A)
 1.21A 1f9gA-5fdnA:
2.7		 1f9gA-5fdnA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kha GLUTAMINE-DEPENDENT
NAD+ SYNTHETASE

(Acinetobacter
baumannii) 		PF00795
(CN_hydrolase)
PF02540
(NAD_synthase) 		4 ASN A 535
TYR A 477
ARG A 529
ARG A 511
 None
 1.02A 1f9gA-5khaA:
undetectable		 1f9gA-5khaA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mew LACCASE 2

(Steccherinum
murashkinskyi) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ARG A 425
ASN A 230
ARG A 200
ASN A 134
 None
 1.34A 1f9gA-5mewA:
undetectable		 1f9gA-5mewA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE

(Chaetomium
thermophilum) 		no annotation 4 ARG A 464
TRP A 370
ARG A  31
ASN A 355
 None
 1.29A 1f9gA-5o82A:
undetectable		 1f9gA-5o82A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Acinetobacter
baumannii) 		PF01676
(Metalloenzyme)
PF06415
(iPGM_N) 		4 ARG A 267
TYR A 352
ARG A 330
ARG A 357
 None
 1.42A 1f9gA-5vpuA:
undetectable		 1f9gA-5vpuA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bo6 -

(-) 		no annotation 4 ARG A 340
TYR A 485
ARG A 574
ASN A 578
 None
E0V  A 701 (-4.4A)
E0V  A 701 (-3.8A)
E0V  A 701 (-3.0A)
 1.24A 1f9gA-6bo6A:
undetectable		 1f9gA-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c13 -

(-) 		no annotation 4 ARG A1278
TYR A1350
ARG A1355
ASN A1343
 None
 1.42A 1f9gA-6c13A:
undetectable		 1f9gA-6c13A:
undetectable