SIMILAR PATTERNS OF AMINO ACIDS FOR 1EUP_A_ASDA452_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE

(Pseudomonas sp.) 		PF00106
(adh_short) 		4 PHE A 139
LEU A 127
LEU A 169
LEU A 130
 None
 0.90A 1eupA-1bdbA:
0.0		 1eupA-1bdbA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cz2 NONSPECIFIC LIPID
TRANSFER PROTEIN

(Triticum
aestivum) 		PF00234
(Tryp_alpha_amyl) 		4 SER A  82
ILE A  81
LEU A  51
LEU A  77
 None
E2P  A  91 (-4.2A)
E2P  A  91 (-3.1A)
E2P  A  91 ( 3.3A)
 0.85A 1eupA-1cz2A:
undetectable		 1eupA-1cz2A:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f6y 5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE

(Moorella
thermoacetica) 		PF00809
(Pterin_bind) 		5 SER A  97
ILE A 120
LEU A 119
LEU A 122
LEU A 157
 None
 1.03A 1eupA-1f6yA:
0.0		 1eupA-1f6yA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h56 TYPE II RESTRICTION
ENZYME PVUII

(Proteus
vulgaris) 		PF09225
(Endonuc-PvuII) 		4 PHE A  32
ILE A  16
LEU A  12
LEU A   9
 None
 0.88A 1eupA-1h56A:
0.0		 1eupA-1h56A:
15.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1jio CYTOCHROME P450
107A1

(Saccharopolyspora
erythraea) 		PF00067
(p450) 		7 TYR A  75
PHE A  86
ILE A 174
LEU A 175
LEU A 240
GLU A 244
LEU A 391
 DEB  A 420 ( 4.8A)
None
DEB  A 420 (-4.8A)
None
DEB  A 420 ( 4.5A)
None
DEB  A 420 ( 4.8A)
 0.59A 1eupA-1jioA:
69.4		 1eupA-1jioA:
98.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1jio CYTOCHROME P450
107A1

(Saccharopolyspora
erythraea) 		PF00067
(p450) 		6 TYR A  75
PHE A  86
SER A 171
ILE A 174
LEU A 240
GLU A 244
 DEB  A 420 ( 4.8A)
None
DEB  A 420 ( 4.8A)
DEB  A 420 (-4.8A)
DEB  A 420 ( 4.5A)
None
 0.75A 1eupA-1jioA:
69.4		 1eupA-1jioA:
98.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1

(Homo sapiens) 		PF01704
(UDPGP) 		4 SER A 471
ILE A 470
LEU A 477
GLU A 475
 None
 0.81A 1eupA-1jv1A:
0.0		 1eupA-1jv1A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nrj SIGNAL RECOGNITION
PARTICLE RECEPTOR
ALPHA SUBUNIT
HOMOLOG

(Saccharomyces
cerevisiae) 		PF09201
(SRX) 		4 SER A 119
ILE A 122
LEU A 123
LEU A  85
 None
 0.66A 1eupA-1nrjA:
0.0		 1eupA-1nrjA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pk1 POLYHOMEOTIC-PROXIMA
L CHROMATIN PROTEIN

(Drosophila
melanogaster) 		PF00536
(SAM_1) 		5 PHE A  25
SER A  77
ILE A  78
GLU A  76
LEU A  50
 None
 1.35A 1eupA-1pk1A:
undetectable		 1eupA-1pk1A:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t0a 2C-METHYL-D-ERYTHRIT
OL
2,4-CYCLODIPHOSPHATE
SYNTHASE

(Shewanella
oneidensis) 		PF02542
(YgbB) 		5 SER A  47
ILE A  50
LEU A  51
LEU A  79
LEU A  85
 None
 1.32A 1eupA-1t0aA:
0.0		 1eupA-1t0aA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uus STAT PROTEIN

(Dictyostelium
discoideum) 		PF00017
(SH2)
PF09267
(Dict-STAT-coil) 		4 PHE A 562
ILE A 543
LEU A 540
LEU A 516
 None
 0.89A 1eupA-1uusA:
0.2		 1eupA-1uusA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vqy HYPOTHETICAL PROTEIN
AGR_PAT_315

(Agrobacterium
fabrum) 		PF07978
(NIPSNAP) 		4 ILE A  10
LEU A  86
GLU A  17
LEU A  83
 None
 0.85A 1eupA-1vqyA:
0.0		 1eupA-1vqyA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vzy 33 KDA CHAPERONIN

(Bacillus
subtilis) 		PF01430
(HSP33) 		4 TYR A  10
SER A 156
ILE A 177
LEU A 195
 None
 0.89A 1eupA-1vzyA:
undetectable		 1eupA-1vzyA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wjw PHOSPHOACETYLGLUCOSA
MINE MUTASE

(Mus musculus) 		PF00408
(PGM_PMM_IV) 		4 ILE A  47
LEU A  92
LEU A  85
GLU A  88
 None
 0.88A 1eupA-1wjwA:
undetectable		 1eupA-1wjwA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yax VIRULENCE SENSOR
PROTEIN PHOQ, SENSOR
DOMAIN

(Salmonella
enterica) 		PF08918
(PhoQ_Sensor) 		4 SER A 108
ILE A 109
LEU A 105
LEU A  95
 None
 0.81A 1eupA-1yaxA:
undetectable		 1eupA-1yaxA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yhu HEMOGLOBIN B2 CHAIN

(Riftia
pachyptila) 		PF00042
(Globin) 		4 PHE D 136
LEU D  94
LEU D  74
LEU D  91
 None
None
HEM  D 160 (-3.7A)
None
 0.85A 1eupA-1yhuD:
undetectable		 1eupA-1yhuD:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bll PROTEIN YFBG

(Escherichia
coli) 		PF01370
(Epimerase) 		4 PHE A 362
SER A 350
ILE A 353
LEU A 357
 None
 0.82A 1eupA-2bllA:
undetectable		 1eupA-2bllA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cb4 MOSQUITOCIDAL TOXIN

(Lysinibacillus
sphaericus) 		no annotation 4 PHE A 185
SER A  61
ILE A  64
LEU A  73
 None
 0.84A 1eupA-2cb4A:
undetectable		 1eupA-2cb4A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ixm SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
REGULATORY SUBUNIT
B'

(Homo sapiens) 		PF03095
(PTPA) 		4 PHE A 159
LEU A 119
LEU A  81
LEU A 112
 None
 0.89A 1eupA-2ixmA:
undetectable		 1eupA-2ixmA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jgn ATP-DEPENDENT RNA
HELICASE DDX3X

(Homo sapiens) 		PF00271
(Helicase_C) 		4 PHE A 515
LEU A 431
GLU A 463
LEU A 434
 None
 0.88A 1eupA-2jgnA:
undetectable		 1eupA-2jgnA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jp2 SPROUTY-RELATED,
EVH1
DOMAIN-CONTAINING
PROTEIN 2

(Homo sapiens) 		PF00568
(WH1) 		4 ILE A  61
LEU A  60
LEU A  73
GLU A  74
 None
 0.84A 1eupA-2jp2A:
undetectable		 1eupA-2jp2A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n47 SLR1183 PROTEIN

(Synechocystis
sp. PCC 6803) 		PF13649
(Methyltransf_25) 		4 PHE A  88
LEU A  36
GLU A  38
LEU A  64
 None
 0.90A 1eupA-2n47A:
undetectable		 1eupA-2n47A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qep RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE N2

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 PHE A 997
ILE A 958
LEU A 962
GLU A1005
 None
 0.82A 1eupA-2qepA:
undetectable		 1eupA-2qepA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vsa MOSQUITOCIDAL TOXIN

(Lysinibacillus
sphaericus) 		PF05588
(Botulinum_HA-17)
PF14200
(RicinB_lectin_2) 		4 PHE A 185
SER A  61
ILE A  64
LEU A  73
 None
 0.86A 1eupA-2vsaA:
undetectable		 1eupA-2vsaA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w1j PUTATIVE SORTASE

(Streptococcus
pneumoniae) 		PF04203
(Sortase) 		4 SER A  56
LEU A 112
GLU A 113
LEU A  51
 None
 0.82A 1eupA-2w1jA:
undetectable		 1eupA-2w1jA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wbl RAC-LIKE GTP-BINDING
PROTEIN ARAC2

(Arabidopsis
thaliana) 		PF00071
(Ras) 		4 ILE C  96
LEU C 101
LEU C 115
LEU C 104
 None
 0.72A 1eupA-2wblC:
undetectable		 1eupA-2wblC:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wiz ARCHAEAL HJC

(Archaeoglobus
fulgidus) 		PF01870
(Hjc) 		4 PHE A  94
ILE A  50
LEU A  12
GLU A   9
 None
 0.88A 1eupA-2wizA:
undetectable		 1eupA-2wizA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a0h PHOTOSYSTEM II CORE
LIGHT HARVESTING
PROTEIN
PHOTOSYSTEM II D2
PROTEIN

(Thermosynechococcus
vulcanus) 		PF00124
(Photo_RC)
PF00421
(PSII) 		5 PHE B 250
SER D 155
ILE D 159
LEU B 460
LEU D 291
 CLA  B1010 ( 3.7A)
CLA  D1004 ( 4.7A)
DGD  B1058 (-4.5A)
DGD  B1058 (-3.6A)
DGD  B1058 ( 4.6A)
 1.24A 1eupA-3a0hB:
undetectable		 1eupA-3a0hB:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bh1 UPF0371 PROTEIN
DIP2346

(Corynebacterium
diphtheriae) 		PF08903
(DUF1846) 		4 PHE A 475
SER A 384
LEU A 388
LEU A 391
 None
None
GOL  A 507 ( 4.5A)
None
 0.85A 1eupA-3bh1A:
undetectable		 1eupA-3bh1A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bq9 PREDICTED ROSSMANN
FOLD
NUCLEOTIDE-BINDING
DOMAIN-CONTAINING
PROTEIN

(Idiomarina
baltica) 		PF03641
(Lysine_decarbox)
PF11892
(DUF3412)
PF14793
(DUF4478) 		4 ILE A 299
LEU A 295
LEU A 262
LEU A 282
 None
 0.79A 1eupA-3bq9A:
undetectable		 1eupA-3bq9A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3l ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE

(Homo sapiens) 		PF00305
(Lipoxygenase) 		4 TYR A 483
PHE A 482
ILE A 478
LEU A 529
 None
 0.84A 1eupA-3d3lA:
undetectable		 1eupA-3d3lA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dmo CYTIDINE DEAMINASE

(Burkholderia
pseudomallei) 		PF00383
(dCMP_cyt_deam_1) 		4 ILE A  75
LEU A 103
GLU A 104
LEU A 107
 None
 0.83A 1eupA-3dmoA:
undetectable		 1eupA-3dmoA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h05 UNCHARACTERIZED
PROTEIN VPA0413

(Vibrio
parahaemolyticus) 		PF01467
(CTP_transf_like) 		4 ILE A  92
LEU A  88
LEU A  32
GLU A  34
 None
 0.63A 1eupA-3h05A:
undetectable		 1eupA-3h05A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h5c PROTEIN Z-DEPENDENT
PROTEASE INHIBITOR

(Homo sapiens) 		PF00079
(Serpin) 		4 SER A  85
LEU A 123
LEU A 107
LEU A 120
 None
 0.86A 1eupA-3h5cA:
undetectable		 1eupA-3h5cA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hd6 AMMONIUM TRANSPORTER
RH TYPE C

(Homo sapiens) 		PF00909
(Ammonium_transp) 		4 PHE A 130
SER A 240
ILE A 239
LEU A 170
 None
 0.70A 1eupA-3hd6A:
0.0		 1eupA-3hd6A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3igo CALMODULIN-DOMAIN
PROTEIN KINASE 1

(Cryptosporidium
parvum) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		4 TYR A 188
ILE A 194
LEU A 127
GLU A 123
 None
 0.90A 1eupA-3igoA:
undetectable		 1eupA-3igoA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3khe CALMODULIN-LIKE
DOMAIN PROTEIN
KINASE ISOFORM 3

(Toxoplasma
gondii) 		PF13499
(EF-hand_7) 		4 PHE A 129
ILE A 140
LEU A 145
LEU A 148
 None
 0.91A 1eupA-3kheA:
undetectable		 1eupA-3kheA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ksy SON OF SEVENLESS
HOMOLOG 1

(Homo sapiens) 		PF00125
(Histone)
PF00169
(PH)
PF00617
(RasGEF)
PF00618
(RasGEF_N)
PF00621
(RhoGEF) 		4 SER A1013
ILE A1016
LEU A 886
LEU A1024
 None
 0.63A 1eupA-3ksyA:
undetectable		 1eupA-3ksyA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ldd CALCIUM-GATED
POTASSIUM CHANNEL
MTHK

(Methanothermobacter
thermautotrophicus) 		PF07885
(Ion_trans_2) 		4 PHE A  54
ILE A  31
LEU A  50
LEU A  79
 None
 0.80A 1eupA-3lddA:
undetectable		 1eupA-3lddA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mm5 SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA

(Archaeoglobus
fulgidus) 		PF00037
(Fer4)
PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 PHE B 332
ILE B 306
LEU B 307
LEU B 320
 None
 0.77A 1eupA-3mm5B:
undetectable		 1eupA-3mm5B:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3olz GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3

(Rattus
norvegicus) 		PF01094
(ANF_receptor) 		4 SER A 129
ILE A 132
LEU A 133
LEU A 157
 None
 0.67A 1eupA-3olzA:
undetectable		 1eupA-3olzA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opb SWI5-DEPENDENT HO
EXPRESSION PROTEIN 4

(Saccharomyces
cerevisiae) 		PF11701
(UNC45-central) 		4 PHE A 104
SER A  90
ILE A  93
LEU A 128
 None
 0.62A 1eupA-3opbA:
undetectable		 1eupA-3opbA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pxi NEGATIVE REGULATOR
OF GENETIC
COMPETENCE CLPC/MECB

(Bacillus
subtilis) 		PF00004
(AAA)
PF02151
(UVR)
PF02861
(Clp_N)
PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		4 PHE A 701
SER A 540
ILE A 705
LEU A 634
 None
 0.82A 1eupA-3pxiA:
undetectable		 1eupA-3pxiA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG

(Mus musculus) 		PF14674
(FANCI_S1-cap)
PF14675
(FANCI_S1)
PF14676
(FANCI_S2)
PF14677
(FANCI_S3)
PF14678
(FANCI_S4)
PF14679
(FANCI_HD1)
PF14680
(FANCI_HD2) 		4 PHE A 385
SER A 361
ILE A 364
LEU A 365
 None
 0.76A 1eupA-3s51A:
1.0		 1eupA-3s51A:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqw ATP-DEPENDENT RNA
HELICASE MSS116,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 PHE A 592
SER A 535
ILE A 534
LEU A 580
 None
U  B   3 ( 4.5A)
None
None
 0.90A 1eupA-3sqwA:
undetectable		 1eupA-3sqwA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vv1 PROTEIN LEC-6

(Caenorhabditis
elegans) 		PF00337
(Gal-bind_lectin) 		4 PHE A  61
ILE A 109
LEU A  98
GLU A  99
 None
 0.89A 1eupA-3vv1A:
undetectable		 1eupA-3vv1A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wvi TYPE-2 RESTRICTION
ENZYME HINDIII

(Haemophilus
influenzae) 		PF09518
(RE_HindIII) 		4 TYR A 218
LEU A 166
LEU A 160
LEU A 165
 None
 0.88A 1eupA-3wviA:
undetectable		 1eupA-3wviA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zqj UVRABC SYSTEM
PROTEIN A

(Mycobacterium
tuberculosis) 		PF00005
(ABC_tran) 		4 SER A 441
ILE A 442
LEU A 109
LEU A 420
 None
 0.88A 1eupA-3zqjA:
undetectable		 1eupA-3zqjA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a3w ARCHAEMETZINCIN

(Archaeoglobus
fulgidus) 		PF07998
(Peptidase_M54) 		4 SER A  52
ILE A  55
LEU A  56
GLU A  84
 None
 0.89A 1eupA-4a3wA:
undetectable		 1eupA-4a3wA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4av6 K(+)-STIMULATED
PYROPHOSPHATE-ENERGI
ZED SODIUM PUMP

(Thermotoga
maritima) 		PF03030
(H_PPase) 		4 SER A 254
ILE A 257
LEU A 258
LEU A 513
 None
 0.73A 1eupA-4av6A:
0.0		 1eupA-4av6A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE

(Aspergillus
fumigatus) 		PF01704
(UDPGP) 		4 SER A 485
ILE A 484
LEU A 491
GLU A 489
 None
 0.82A 1eupA-4bmaA:
undetectable		 1eupA-4bmaA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bsx TIR
DOMAIN-CONTAINING
ADAPTER MOLECULE 1

(Homo sapiens) 		no annotation 4 LEU A  26
LEU A 102
GLU A 106
LEU A  15
 None
 0.76A 1eupA-4bsxA:
undetectable		 1eupA-4bsxA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d0p COP9 SIGNALOSOME
COMPLEX SUBUNIT 4

(Homo sapiens) 		PF01399
(PCI) 		4 ILE A 272
LEU A 327
LEU A 315
LEU A 324
 None
 0.85A 1eupA-4d0pA:
undetectable		 1eupA-4d0pA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4db4 ATP-DEPENDENT RNA
HELICASE MSS116,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF00271
(Helicase_C) 		4 PHE A 592
SER A 535
ILE A 534
LEU A 580
 None
 0.90A 1eupA-4db4A:
undetectable		 1eupA-4db4A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eba MRNA
3'-END-PROCESSING
PROTEIN RNA14
RNA15

(Kluyveromyces
lactis) 		PF05843
(Suf)
PF14327
(CSTF2_hinge) 		5 PHE G 161
ILE G 175
LEU G 178
LEU A 654
LEU G 146
 None
 1.42A 1eupA-4ebaG:
undetectable		 1eupA-4ebaG:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eg2 CYTIDINE DEAMINASE

(Vibrio cholerae) 		PF00383
(dCMP_cyt_deam_1)
PF08211
(dCMP_cyt_deam_2) 		4 PHE A 135
ILE A 108
LEU A 176
LEU A 145
 None
 0.67A 1eupA-4eg2A:
undetectable		 1eupA-4eg2A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4egt MAJOR CAPSID PROTEIN
VP60

(Rabbit
hemorrhagic
disease virus) 		PF00915
(Calici_coat) 		4 PHE A 519
ILE A 545
LEU A 544
LEU A 547
 None
 0.60A 1eupA-4egtA:
undetectable		 1eupA-4egtA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fog THYMIDYLATE SYNTHASE

(Mycobacterium
tuberculosis) 		PF00303
(Thymidylat_synt) 		4 PHE A 150
LEU A 116
LEU A 184
LEU A 119
 None
 0.77A 1eupA-4fogA:
undetectable		 1eupA-4fogA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g7a CARBONATE
DEHYDRATASE

(Sulfurihydrogenibium
sp. YO3AOP1) 		PF00194
(Carb_anhydrase) 		4 PHE A  88
ILE A 137
LEU A 159
LEU A 201
 None
 0.77A 1eupA-4g7aA:
undetectable		 1eupA-4g7aA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4htw GAG PROTEIN

(Simian
immunodeficiency
virus) 		PF00607
(Gag_p24) 		4 PHE A  39
ILE A  51
LEU A  55
LEU A  14
 None
 0.90A 1eupA-4htwA:
undetectable		 1eupA-4htwA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i16 CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 11

(Mus musculus) 		PF00619
(CARD) 		4 PHE A  91
SER A  34
ILE A  37
LEU A  77
 None
 0.64A 1eupA-4i16A:
undetectable		 1eupA-4i16A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jup CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 11

(Homo sapiens) 		PF00619
(CARD) 		4 PHE A  91
SER A  34
ILE A  37
LEU A  77
 None
 0.76A 1eupA-4jupA:
undetectable		 1eupA-4jupA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k6l PUTATIVE
PERTUSSIS-LIKE TOXIN
SUBUNIT

(Salmonella
enterica) 		PF02917
(Pertussis_S1) 		4 TYR G  95
SER G 139
ILE G 140
LEU G 141
 None
 0.87A 1eupA-4k6lG:
undetectable		 1eupA-4k6lG:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kbm DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA

(Mycobacterium
tuberculosis) 		PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1) 		4 PHE A 151
ILE A 383
LEU A  58
LEU A  84
 None
 0.75A 1eupA-4kbmA:
undetectable		 1eupA-4kbmA:
25.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mhc NUCLEOPORIN NUP157

(Saccharomyces
cerevisiae) 		PF08801
(Nucleoporin_N) 		4 PHE A 729
ILE A 812
LEU A 809
LEU A 852
 None
 0.89A 1eupA-4mhcA:
undetectable		 1eupA-4mhcA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mlc EXTRACELLULAR
LIGAND-BINDING
RECEPTOR

(Desulfitobacterium
hafniense) 		PF13458
(Peripla_BP_6) 		4 PHE A 211
ILE A 220
LEU A 183
GLU A 184
 None
 0.87A 1eupA-4mlcA:
undetectable		 1eupA-4mlcA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nh0 CELL
DIVISIONFTSK/SPOIIIE

(Thermomonospora
curvata) 		PF01580
(FtsK_SpoIIIE) 		4 PHE A 686
ILE A 645
LEU A 647
LEU A 659
 None
 0.85A 1eupA-4nh0A:
undetectable		 1eupA-4nh0A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ppm AMINOTRANSFERASE

(Serratia sp.
FS14) 		PF00202
(Aminotran_3) 		4 PHE A 837
ILE A 823
LEU A 718
LEU A 736
 None
 0.74A 1eupA-4ppmA:
0.0		 1eupA-4ppmA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qb1 XYN30D

(Paenibacillus
barcinonensis) 		PF03422
(CBM_6) 		4 PHE A  70
ILE A 123
LEU A 121
GLU A  54
 None
 0.90A 1eupA-4qb1A:
undetectable		 1eupA-4qb1A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u6u COG5

(Kluyveromyces
lactis) 		PF10392
(COG5) 		4 PHE B 333
SER B 351
ILE B 354
LEU B 385
 None
 0.86A 1eupA-4u6uB:
0.0		 1eupA-4u6uB:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u8u GLOBIN A CHAIN

(Glossoscolex
paulistus) 		PF00042
(Globin) 		4 PHE A 137
LEU A  95
LEU A  75
LEU A  92
 HEM  A 201 (-4.8A)
HEM  A 201 (-4.9A)
HEM  A 201 ( 4.7A)
None
 0.88A 1eupA-4u8uA:
undetectable		 1eupA-4u8uA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uqg DNA POLYMERASE

(Geobacillus
stearothermophilus) 		PF00476
(DNA_pol_A) 		4 ILE A 833
LEU A 825
GLU A 835
LEU A 824
 None
 0.76A 1eupA-4uqgA:
undetectable		 1eupA-4uqgA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uqz HSIB1
HSIE1

(Pseudomonas
aeruginosa) 		PF05591
(T6SS_VipA)
PF07024
(ImpE) 		4 TYR B  28
SER A  53
GLU A  49
LEU A  47
 None
 0.89A 1eupA-4uqzB:
undetectable		 1eupA-4uqzB:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w4t MXAA

(Stigmatella
aurantiaca) 		PF07993
(NAD_binding_4) 		4 ILE A1135
LEU A1321
GLU A1324
LEU A1330
 None
 0.91A 1eupA-4w4tA:
undetectable		 1eupA-4w4tA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y6o NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-2

(Homo sapiens) 		PF02146
(SIR2) 		4 TYR A 139
SER A  88
ILE A  93
LEU A 172
 None
 0.87A 1eupA-4y6oA:
undetectable		 1eupA-4y6oA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnn CAPSID PROTEIN VP1
CAPSID PROTEIN VP3

(Enterovirus D) 		PF00073
(Rhv) 		4 PHE A  62
ILE C 102
LEU C  98
LEU A 109
 None
 0.63A 1eupA-5bnnA:
undetectable		 1eupA-5bnnA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bza BETA-N-ACETYLHEXOSAM
INIDASE

(Thermotoga
neapolitana) 		PF00933
(Glyco_hydro_3) 		4 PHE A  45
SER A  62
ILE A  34
LEU A  72
 None
 0.84A 1eupA-5bzaA:
undetectable		 1eupA-5bzaA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gjy MHC CLASS I ANTIGEN

(Anas
platyrhynchos) 		PF00129
(MHC_I)
PF07654
(C1-set) 		4 SER A 213
ILE A 212
GLU A 261
LEU A 265
 None
 0.86A 1eupA-5gjyA:
undetectable		 1eupA-5gjyA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gz4 SNAKE VENOM
PHOSPHODIESTERASE
(PDE)

(Naja atra) 		PF01033
(Somatomedin_B)
PF01223
(Endonuclease_NS)
PF01663
(Phosphodiest) 		4 TYR A 597
SER A 620
LEU A 584
LEU A 825
 None
 0.90A 1eupA-5gz4A:
undetectable		 1eupA-5gz4A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h7w VENOM
5'-NUCLEOTIDASE

(Naja atra) 		no annotation 4 PHE A 436
ILE A 388
LEU A 498
LEU A 432
 None
 0.83A 1eupA-5h7wA:
undetectable		 1eupA-5h7wA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5im6 DESIGNED
SELF-ASSEMBLING
ICOSAHEDRAL CAGE
I32-28 TRIMERIC
SUBUNIT

(Burkholderia
thailandensis) 		PF01923
(Cob_adeno_trans) 		5 PHE A 160
ILE A 110
LEU A 176
LEU A 106
GLU A 107
 None
 1.34A 1eupA-5im6A:
undetectable		 1eupA-5im6A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jjt SERINE/THREONINE-PRO
TEIN PHOSPHATASE 5

(Arabidopsis
thaliana) 		PF00149
(Metallophos)
PF00515
(TPR_1)
PF08321
(PPP5)
PF13431
(TPR_17) 		4 PHE A 321
SER A 265
ILE A 269
GLU A 304
 None
 0.82A 1eupA-5jjtA:
undetectable		 1eupA-5jjtA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kuf GLUTAMATE RECEPTOR
IONOTROPIC, KAINATE
2

(Rattus
norvegicus) 		PF00060
(Lig_chan)
PF01094
(ANF_receptor)
PF10613
(Lig_chan-Glu_bd) 		4 SER A 126
ILE A 129
LEU A 130
LEU A 154
 None
 0.88A 1eupA-5kufA:
undetectable		 1eupA-5kufA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kwa PROTEASOME-ASSOCIATE
D ATPASE

(Mycobacterium
tuberculosis) 		PF00004
(AAA)
PF16450
(Prot_ATP_ID_OB) 		4 TYR A 487
SER A 550
ILE A 551
LEU A 547
 None
 0.83A 1eupA-5kwaA:
undetectable		 1eupA-5kwaA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqx NON-STRUCTURAL
PROTEIN3

(Venezuelan
equine
encephalitis
virus) 		no annotation 4 SER A  91
ILE A  92
GLU A  90
LEU A 132
 None
 0.66A 1eupA-5mqxA:
undetectable		 1eupA-5mqxA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nd7 KINESIN-LIKE PROTEIN
KIF20A

(Mus musculus) 		PF00225
(Kinesin) 		4 SER C 182
ILE C 186
LEU C 183
LEU C 403
 None
 0.85A 1eupA-5nd7C:
undetectable		 1eupA-5nd7C:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5on7 EPSIN-2

(Saccharomyces
cerevisiae) 		no annotation 4 SER A  76
LEU A  77
LEU A  59
LEU A 129
 None
 0.77A 1eupA-5on7A:
undetectable		 1eupA-5on7A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oon UNDECAPRENYL-DIPHOSP
HATASE

(Escherichia
coli) 		no annotation 4 PHE A 195
ILE A  95
LEU A  90
LEU A  68
 None
 0.90A 1eupA-5oonA:
undetectable		 1eupA-5oonA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tw1 DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA

(Mycolicibacterium
smegmatis) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF10385
(RNA_pol_Rpb2_45) 		4 PHE C 148
ILE C 380
LEU C  55
LEU C  81
 None
 0.80A 1eupA-5tw1C:
undetectable		 1eupA-5tw1C:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u7w APYRASE

(Trifolium
repens) 		PF01150
(GDA1_CD39) 		4 SER A  99
ILE A 102
LEU A 103
LEU A  85
 None
 0.84A 1eupA-5u7wA:
undetectable		 1eupA-5u7wA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans) 		PF00171
(Aldedh) 		4 SER A 115
ILE A 118
LEU A 119
LEU A 221
 None
 0.88A 1eupA-5ujuA:
0.0		 1eupA-5ujuA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ux4 CATHEPSIN D

(Rattus
norvegicus) 		no annotation 4 PHE A 301
ILE A 269
LEU A 208
GLU A 209
 None
 0.87A 1eupA-5ux4A:
undetectable		 1eupA-5ux4A:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xtg 2,3-DIHYDROXY-2,3-DI
HYDROPHENYLPROPIONAT
E DEHYDROGENASE

(Pseudomonas sp.
MC1) 		PF13561
(adh_short_C2) 		4 ILE B 121
LEU B 125
LEU B 167
LEU B 128
 None
 0.87A 1eupA-5xtgB:
undetectable		 1eupA-5xtgB:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yhp COLD ACTIVE PROLINE
IMINOPEPTIDASE

(Glaciozyma
antarctica) 		no annotation 4 TYR A  61
SER A   3
LEU A   4
GLU A 305
 None
 0.88A 1eupA-5yhpA:
undetectable		 1eupA-5yhpA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ckg D-GLYCERATE 3-KINASE

(Cryptococcus
neoformans) 		no annotation 4 TYR A 275
SER A 214
ILE A 215
LEU A  91
 None
 0.90A 1eupA-6ckgA:
undetectable		 1eupA-6ckgA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6q EXOSOME RNA HELICASE
MTR4

(Homo sapiens) 		no annotation 4 SER M 882
ILE M 880
LEU M1003
GLU M1002
 C  O  22 ( 3.5A)
None
None
C  O  22 ( 3.0A)
 0.81A 1eupA-6d6qM:
undetectable		 1eupA-6d6qM:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN

(Streptococcus
pyogenes;
Vibrio cholerae) 		no annotation 4 PHE A 811
ILE A 919
LEU A 920
LEU A 917
 None
 0.77A 1eupA-6en3A:
undetectable		 1eupA-6en3A:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIQ
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIR

(Salmonella
enterica) 		no annotation 4 ILE F 226
LEU F 222
LEU A 198
LEU G  25
 None
 0.86A 1eupA-6f2dF:
undetectable		 1eupA-6f2dF:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f34 AMINO ACID
TRANSPORTER

(Geobacillus
kaustophilus) 		no annotation 4 PHE A 408
ILE A 258
LEU A 261
LEU A  77
 None
 0.77A 1eupA-6f34A:
0.0		 1eupA-6f34A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4

(Mus musculus) 		no annotation 4 SER M 157
ILE M 158
LEU M 154
GLU M 123
 None
 0.89A 1eupA-6g2jM:
undetectable		 1eupA-6g2jM:
11.86