SIMILAR PATTERNS OF AMINO ACIDS FOR 1ERR_B_RALB600_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b4a | ARGININE REPRESSOR (Geobacillusstearothermophilus) |
PF01316(Arg_repressor)PF02863(Arg_repressor_C) | 5 | LEU A 94LEU A 93ILE A 122LEU A 80LEU A 149 | None | 1.21A | 1errB-1b4aA:undetectable | 1errB-1b4aA:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ebv | PROSTAGLANDIN H2SYNTHASE (Ovis aries) |
PF00008(EGF)PF03098(An_peroxidase) | 5 | LEU A 177LEU A 182ILE A 188LEU A 491LEU A 494 | None | 1.15A | 1errB-1ebvA:undetectable | 1errB-1ebvA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gt9 | KUMAMOLYSIN (Bacillussubtilis) |
PF00082(Peptidase_S8) | 5 | LEU 1 355LEU 1 356ILE 1 349LEU 1 287LEU 1 188 | None | 1.19A | 1errB-1gt91:undetectable | 1errB-1gt91:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) |
PF00104(Hormone_recep) | 6 | TRP A 318LEU A 322ILE A 385LEU A 476LEU A 487LEU A 490 | NoneLPP A 1 ( 4.8A)NoneLPP A 1 (-4.2A)NoneNone | 0.89A | 1errB-1hg4A:24.1 | 1errB-1hg4A:27.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j1w | ISOCITRATEDEHYDROGENASE (Azotobactervinelandii) |
PF03971(IDH) | 5 | TRP A 667LEU A 23ILE A 81LEU A 614LEU A 671 | None | 1.20A | 1errB-1j1wA:undetectable | 1errB-1j1wA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nne | DNA MISMATCH REPAIRPROTEIN MUTS (Thermusaquaticus) |
PF00488(MutS_V)PF01624(MutS_I)PF05188(MutS_II)PF05190(MutS_IV)PF05192(MutS_III) | 5 | GLU A 333LEU A 332LEU A 287LEU A 359LEU A 356 | None | 1.16A | 1errB-1nneA:undetectable | 1errB-1nneA:16.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1olt | OXYGEN-INDEPENDENTCOPROPORPHYRINOGENIII OXIDASE (Escherichiacoli) |
PF04055(Radical_SAM)PF06969(HemN_C) | 5 | TRP A 110LEU A 118ILE A 151LEU A 159LEU A 108 | None | 1.15A | 1errB-1oltA:undetectable | 1errB-1oltA:20.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1pcg | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 8 | ALA A 350GLU A 353TRP A 383LEU A 387LEU A 391ARG A 394ILE A 424LEU A 525 | EST A 1 ( 3.7A)EST A 1 (-2.8A)NoneEST A 1 (-4.0A)EST A 1 ( 3.9A)EST A 1 (-3.7A)EST A 1 ( 4.5A)EST A 1 (-3.6A) | 0.59A | 1errB-1pcgA:32.2 | 1errB-1pcgA:98.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1pcg | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 7 | THR A 347ALA A 350GLU A 353TRP A 383LEU A 387LEU A 391ARG A 394 | NoneEST A 1 ( 3.7A)EST A 1 (-2.8A)NoneEST A 1 (-4.0A)EST A 1 ( 3.9A)EST A 1 (-3.7A) | 0.29A | 1errB-1pcgA:32.2 | 1errB-1pcgA:98.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1pcg | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | THR A 347GLU A 353LEU A 354TRP A 383ARG A 394 | NoneEST A 1 (-2.8A)NoneNoneEST A 1 (-3.7A) | 0.57A | 1errB-1pcgA:32.2 | 1errB-1pcgA:98.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pgv | TROPOMODULIN TMD-1 (Caenorhabditiselegans) |
no annotation | 5 | ALA A 347GLU A 350LEU A 318ILE A 286LEU A 374 | None | 1.19A | 1errB-1pgvA:undetectable | 1errB-1pgvA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s16 | TOPOISOMERASE IVSUBUNIT B (Escherichiacoli) |
PF00204(DNA_gyraseB)PF02518(HATPase_c) | 5 | THR A1264ALA A1317LEU A1253LEU A1230LEU A1287 | None | 1.21A | 1errB-1s16A:undetectable | 1errB-1s16A:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t6p | PHENYLALANINEAMMONIA-LYASE (Rhodotorulatoruloides) |
PF00221(Lyase_aromatic) | 5 | LEU A 665LEU A 532ILE A 691LEU A 292LEU A 711 | None | 1.14A | 1errB-1t6pA:undetectable | 1errB-1t6pA:16.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tlq | HYPOTHETICAL PROTEINYPJQ (Bacillussubtilis) |
PF04608(PgpA) | 5 | ALA A 149LEU A 150LEU A 104ILE A 98LEU A 19 | None | 1.05A | 1errB-1tlqA:undetectable | 1errB-1tlqA:23.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tqh | CARBOXYLESTERASEPRECURSOR (Geobacillusstearothermophilus) |
PF12146(Hydrolase_4) | 5 | THR A 163ALA A 166GLU A 169LEU A 170LEU A 95 | NoneNoneNoneNone4PA A 701 (-4.2A) | 1.06A | 1errB-1tqhA:undetectable | 1errB-1tqhA:19.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1uhl | RETINOIC ACIDRECEPTOR RXR-BETA (Homo sapiens) |
PF00104(Hormone_recep) | 5 | ALA A 343TRP A 376LEU A 380ARG A 387ILE A 499 | MEI A1001 (-3.3A)NoneMEI A1001 (-3.8A)MEI A1001 (-3.6A)None | 0.98A | 1errB-1uhlA:22.5 | 1errB-1uhlA:31.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bco | SUCCINYLGLUTAMATEDESUCCINYLASE (Vibrioparahaemolyticus) |
PF04952(AstE_AspA) | 5 | ALA A 68GLU A 71LEU A 72LEU A 231LEU A 241 | None | 0.96A | 1errB-2bcoA:undetectable | 1errB-2bcoA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e4u | METABOTROPICGLUTAMATE RECEPTOR 3 (Rattusnorvegicus) |
PF01094(ANF_receptor)PF07562(NCD3G) | 5 | ALA A 403GLU A 433LEU A 404LEU A 41LEU A 91 | None | 1.21A | 1errB-2e4uA:undetectable | 1errB-2e4uA:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eu9 | DUAL SPECIFICITYPROTEIN KINASE CLK3 (Homo sapiens) |
PF00069(Pkinase) | 5 | GLU A 366LEU A 373LEU A 445LEU A 431LEU A 390 | None | 1.21A | 1errB-2eu9A:undetectable | 1errB-2eu9A:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fq1 | ISOCHORISMATASE (Escherichiacoli) |
PF00550(PP-binding)PF00857(Isochorismatase) | 5 | ALA A 177LEU A 178ILE A 72LEU A 206LEU A 190 | None | 1.14A | 1errB-2fq1A:undetectable | 1errB-2fq1A:19.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2gpv | ESTROGEN-RELATEDRECEPTOR GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 5 | ALA A 272GLU A 275TRP A 305LEU A 309ARG A 316 | OHT A 500 (-3.5A)OHT A 500 (-2.6A)NoneOHT A 500 ( 4.0A)OHT A 500 (-3.8A) | 0.52A | 1errB-2gpvA:26.0 | 1errB-2gpvA:36.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2it1 | 362AA LONGHYPOTHETICALMALTOSE/MALTODEXTRINTRANSPORTATP-BINDING PROTEIN (Pyrococcushorikoshii) |
PF00005(ABC_tran) | 5 | THR A 191LEU A 157LEU A 46ILE A 212LEU A 176 | None | 1.18A | 1errB-2it1A:undetectable | 1errB-2it1A:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j04 | HYPOTHETICAL PROTEINYPL007C (Saccharomycescerevisiae) |
PF12660(zf-TFIIIC) | 5 | ALA A 462LEU A 458LEU A 475LEU A 427LEU A 430 | None | 0.87A | 1errB-2j04A:undetectable | 1errB-2j04A:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k3q | TUSP1 (Nephilaantipodiana) |
PF16763(Spidroin_N) | 5 | ALA A 11LEU A 10LEU A 33LEU A 87LEU A 91 | None | 1.08A | 1errB-2k3qA:undetectable | 1errB-2k3qA:16.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o1w | ENDOPLASMIN (Canis lupus) |
PF00183(HSP90)PF02518(HATPase_c) | 5 | THR A 248LEU A 104LEU A 101LEU A 163LEU A 159 | None | 1.23A | 1errB-2o1wA:undetectable | 1errB-2o1wA:19.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ocf | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | ALA A 350GLU A 353TRP A 383LEU A 387LEU A 525 | EST A 596 ( 3.9A)EST A 596 (-2.7A)NoneEST A 596 ( 4.2A)EST A 596 (-3.6A) | 0.76A | 1errB-2ocfA:31.1 | 1errB-2ocfA:99.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ocf | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 8 | THR A 347ALA A 350GLU A 353TRP A 383LEU A 387LEU A 391ARG A 394ILE A 424 | NoneEST A 596 ( 3.9A)EST A 596 (-2.7A)NoneEST A 596 ( 4.2A)EST A 596 ( 4.6A)EST A 596 (-4.0A)EST A 596 ( 4.7A) | 0.66A | 1errB-2ocfA:31.1 | 1errB-2ocfA:99.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ocf | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 6 | THR A 347GLU A 353LEU A 354TRP A 383LEU A 391ARG A 394 | NoneEST A 596 (-2.7A)NoneNoneEST A 596 ( 4.6A)EST A 596 (-4.0A) | 0.70A | 1errB-2ocfA:31.1 | 1errB-2ocfA:99.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ql2 | NEUROGENICDIFFERENTIATIONFACTOR 1TRANSCRIPTION FACTORE2-ALPHA (Mus musculus) |
PF00010(HLH) | 5 | ALA A 561GLU A 564LEU A 565LEU B 124LEU A 585 | None | 1.00A | 1errB-2ql2A:undetectable | 1errB-2ql2A:14.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qs9 | RETINOBLASTOMA-BINDING PROTEIN 9 (Homo sapiens) |
PF06821(Ser_hydrolase) | 5 | ALA A 92LEU A 181LEU A 182ILE A 175LEU A 153 | None | 1.18A | 1errB-2qs9A:undetectable | 1errB-2qs9A:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r5f | TRANSCRIPTIONALREGULATOR, PUTATIVE (Pseudomonassyringae groupgenomosp. 3) |
PF04198(Sugar-bind) | 5 | ALA A 100LEU A 104LEU A 281ILE A 213LEU A 164 | None | 0.97A | 1errB-2r5fA:undetectable | 1errB-2r5fA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vec | PIRIN-LIKE PROTEINYHAK (Escherichiacoli) |
PF02678(Pirin) | 5 | LEU A 91LEU A 92ILE A 143LEU A 112LEU A 48 | None | 1.19A | 1errB-2vecA:undetectable | 1errB-2vecA:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w0m | SSO2452 (Sulfolobussolfataricus) |
PF06745(ATPase) | 5 | ALA A 134LEU A 135LEU A 91ILE A 66LEU A 150 | None | 0.99A | 1errB-2w0mA:undetectable | 1errB-2w0mA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w8s | PHOSPHONATEMONOESTER HYDROLASE (Paraburkholderiacaryophylli) |
PF00884(Sulfatase)PF16347(DUF4976) | 5 | THR A 193ALA A 196LEU A 200LEU A 210LEU A 102 | None | 0.81A | 1errB-2w8sA:undetectable | 1errB-2w8sA:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wbp | L-ARGININEBETA-HYDROXYLASE (Streptomycesvinaceus) |
PF02668(TauD) | 5 | ALA A 125LEU A 127LEU A 57ARG A 353LEU A 71 | None | 1.24A | 1errB-2wbpA:undetectable | 1errB-2wbpA:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x0q | ALCALIGINBIOSYNTHESIS PROTEIN (Bordetellabronchiseptica) |
PF04183(IucA_IucC)PF06276(FhuF) | 5 | LEU A 424TRP A 423LEU A 409ILE A 154LEU A 455 | None | 1.15A | 1errB-2x0qA:undetectable | 1errB-2x0qA:17.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xes | PROTEIN PAT1 HOMOLOG1 (Homo sapiens) |
PF09770(PAT1) | 5 | THR A 616ALA A 617LEU A 659LEU A 644LEU A 647 | None | 1.12A | 1errB-2xesA:undetectable | 1errB-2xesA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ypb | T-CELL ACUTELYMPHOCYTIC LEUKEMIAPROTEIN 1TRANSCRIPTION FACTORE2-ALPHA (Homo sapiens) |
PF00010(HLH) | 5 | ALA A 206GLU A 209LEU A 210LEU B 569LEU A 229 | None | 1.04A | 1errB-2ypbA:undetectable | 1errB-2ypbA:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ypb | T-CELL ACUTELYMPHOCYTIC LEUKEMIAPROTEIN 1TRANSCRIPTION FACTORE2-ALPHA (Homo sapiens) |
PF00010(HLH) | 5 | ALA B 565GLU B 568LEU B 569LEU A 210LEU B 589 | None | 0.97A | 1errB-2ypbB:undetectable | 1errB-2ypbB:16.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ys6 | PHOSPHORIBOSYLGLYCINAMIDE SYNTHETASE (Geobacilluskaustophilus) |
PF01071(GARS_A)PF02843(GARS_C)PF02844(GARS_N) | 5 | ALA A 256GLU A 260LEU A 257LEU A 109LEU A 268 | None | 0.89A | 1errB-2ys6A:undetectable | 1errB-2ys6A:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zbm | PROTEIN-TYROSINE-PHOSPHATASE (Shewanella sp.) |
PF00149(Metallophos) | 5 | LEU A 90ILE A 187LEU A 145LEU A 76LEU A 315 | None | 1.00A | 1errB-2zbmA:undetectable | 1errB-2zbmA:23.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zuk | ALPHA-AMINO-EPSILON-CAPROLACTAM RACEMASE (Achromobacterobae) |
PF00202(Aminotran_3) | 5 | ALA A 89GLU A 90LEU A 88LEU A 275LEU A 269 | None | 1.20A | 1errB-2zukA:undetectable | 1errB-2zukA:19.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bm3 | PSPGI RESTRICTIONENDONUCLEASE (Pyrococcus sp.GI-H) |
PF09019(EcoRII-C) | 5 | LEU A 111ILE A 66LEU A 31LEU A 37LEU A 40 | None | 1.23A | 1errB-3bm3A:undetectable | 1errB-3bm3A:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3deg | GTP-BINDING PROTEINLEPA (Escherichiacoli) |
PF00009(GTP_EFTU)PF00679(EFG_C)PF03144(GTP_EFTU_D2)PF06421(LepA_C) | 5 | GLU C 356LEU C 355ILE C 52LEU C 317LEU C 314 | None | 1.06A | 1errB-3degC:undetectable | 1errB-3degC:18.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dzu | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
PF00104(Hormone_recep)PF00105(zf-C4) | 5 | ALA A 272LEU A 276TRP A 305LEU A 309ILE A 428 | 9CR A7223 (-4.2A)NoneNone9CR A7223 ( 4.4A)None | 0.87A | 1errB-3dzuA:22.1 | 1errB-3dzuA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eag | UDP-N-ACETYLMURAMATE:L-ALANYL-GAMMA-D-GLUTAMYL-MESO-DIAMINOPIMELATE LIGASE (Neisseriameningitidis) |
PF01225(Mur_ligase)PF08245(Mur_ligase_M) | 5 | THR A 154ALA A 133GLU A 128LEU A 132ILE A 20 | None | 1.21A | 1errB-3eagA:undetectable | 1errB-3eagA:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gc2 | O-SUCCINYLBENZOATESYNTHASE (Salmonellaenterica) |
PF13378(MR_MLE_C) | 5 | ALA A 90LEU A 91LEU A 34LEU A 63LEU A 77 | None | 1.22A | 1errB-3gc2A:undetectable | 1errB-3gc2A:23.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h3b | RECEPTORTYROSINE-PROTEINKINASE ERBB-2 (Homo sapiens) |
PF01030(Recep_L_domain) | 5 | LEU A 40ILE A 150LEU A 120LEU A 52LEU A 49 | None | 1.20A | 1errB-3h3bA:undetectable | 1errB-3h3bA:24.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h6e | CARBOHYDRATE KINASE,FGGY (Novosphingobiumaromaticivorans) |
PF00370(FGGY_N) | 5 | ALA A 155LEU A 158ILE A 79LEU A 55LEU A 59 | None | 1.17A | 1errB-3h6eA:undetectable | 1errB-3h6eA:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i3a | ACYL-[ACYL-CARRIER-PROTEIN]--UDP-N-ACETYLGLUCOSAMINEO-ACYLTRANSFERASE (Leptospirainterrogans) |
PF00132(Hexapep)PF13720(Acetyltransf_11) | 5 | ALA A 134LEU A 136LEU A 169LEU A 142LEU A 124 | None | 0.98A | 1errB-3i3aA:undetectable | 1errB-3i3aA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i3a | ACYL-[ACYL-CARRIER-PROTEIN]--UDP-N-ACETYLGLUCOSAMINEO-ACYLTRANSFERASE (Leptospirainterrogans) |
PF00132(Hexapep)PF13720(Acetyltransf_11) | 5 | THR A 131ALA A 134LEU A 136LEU A 142LEU A 124 | None | 1.06A | 1errB-3i3aA:undetectable | 1errB-3i3aA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jc7 | DNA REPLICATIONCOMPLEX GINS PROTEINPSF2 (Saccharomycescerevisiae) |
PF05916(Sld5) | 5 | GLU B 97LEU B 93LEU B 98ILE B 151LEU B 126 | None | 1.12A | 1errB-3jc7B:undetectable | 1errB-3jc7B:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jw4 | TRANSCRIPTIONALREGULATOR, MARR/EMRRFAMILY (Clostridiumacetobutylicum) |
PF01047(MarR) | 5 | ALA A 106GLU A 109LEU A 107LEU A 34LEU A 36 | None | 1.23A | 1errB-3jw4A:undetectable | 1errB-3jw4A:23.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k96 | GLYCEROL-3-PHOSPHATEDEHYDROGENASE[NAD(P)+] (Coxiellaburnetii) |
PF01210(NAD_Gly3P_dh_N)PF07479(NAD_Gly3P_dh_C) | 5 | LEU A 293ILE A 92LEU A 119LEU A 187LEU A 226 | None | 1.12A | 1errB-3k96A:undetectable | 1errB-3k96A:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nfq | TRANSCRIPTION FACTORIWS1 (Saccharomycescerevisiae) |
PF08711(Med26) | 5 | ALA A 105LEU A 106LEU A 63LEU A 56LEU A 85 | None | 1.19A | 1errB-3nfqA:undetectable | 1errB-3nfqA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rk6 | POLYADENYLATE-BINDINGPROTEIN-INTERACTINGPROTEIN 1 (Homo sapiens) |
PF02854(MIF4G) | 5 | ALA A 117GLU A 120LEU A 121LEU A 79LEU A 150 | None | 0.95A | 1errB-3rk6A:undetectable | 1errB-3rk6A:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vgo | E3 UBIQUITIN-PROTEINLIGASE CBL-B (Homo sapiens) |
PF02262(Cbl_N)PF02761(Cbl_N2)PF02762(Cbl_N3) | 5 | ALA A 121LEU A 143LEU A 78LEU A 67LEU A 65 | None | 1.08A | 1errB-3vgoA:undetectable | 1errB-3vgoA:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vgo | E3 UBIQUITIN-PROTEINLIGASE CBL-B (Homo sapiens) |
PF02262(Cbl_N)PF02761(Cbl_N2)PF02762(Cbl_N3) | 5 | ALA A 121LEU A 146LEU A 78LEU A 67LEU A 65 | None | 0.86A | 1errB-3vgoA:undetectable | 1errB-3vgoA:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w1g | DNA LIGASE 4 (Homo sapiens) |
PF01068(DNA_ligase_A_M)PF04675(DNA_ligase_A_N)PF04679(DNA_ligase_A_C) | 5 | LEU A 152LEU A 221ILE A 203LEU A 194LEU A 186 | None | 0.87A | 1errB-3w1gA:undetectable | 1errB-3w1gA:17.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zco | REGULATORY PROTEINSIR3 (Saccharomycescerevisiae) |
no annotation | 5 | ALA A 902GLU A 905LEU A 860ILE A 855LEU A 923 | None | 1.00A | 1errB-3zcoA:undetectable | 1errB-3zcoA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zs6 | PERIPLASMICOLIGOPEPTIDE-BINDINGPROTEIN (Burkholderiapseudomallei) |
PF00496(SBP_bac_5) | 5 | ALA A 328LEU A 329LEU A 385LEU A 320LEU A 313 | None | 1.12A | 1errB-3zs6A:undetectable | 1errB-3zs6A:17.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a9a | RIBOSOME-INTERACTINGGTPASE 1 (Saccharomycescerevisiae) |
PF01926(MMR_HSR1)PF02824(TGS)PF16897(MMR_HSR1_Xtn) | 5 | ALA A 112TRP A 288LEU A 293LEU A 313LEU A 284 | None | 1.02A | 1errB-4a9aA:undetectable | 1errB-4a9aA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fmc | RORF2 (Escherichiacoli) |
PF06872(EspG) | 5 | LEU A 58LEU A 131LEU A 130LEU A 82LEU A 79 | None | 1.19A | 1errB-4fmcA:undetectable | 1errB-4fmcA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fwv | TTC1975 PEPTIDASE (Meiothermustaiwanensis) |
PF13654(AAA_32) | 5 | GLU A 98LEU A 79LEU A 255LEU A 228LEU A 217 | None | 1.11A | 1errB-4fwvA:undetectable | 1errB-4fwvA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gl8 | OLIGOPEPTIDE ABCTRANSPORTER OPPAIV (Borreliellaburgdorferi) |
PF00496(SBP_bac_5) | 5 | ALA A 309LEU A 310LEU A 359LEU A 301LEU A 294 | None | 1.23A | 1errB-4gl8A:undetectable | 1errB-4gl8A:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4grx | AMINOTRANSFERASE (Paracoccusdenitrificans) |
PF00202(Aminotran_3) | 5 | ALA A 383GLU A 382LEU A 381ARG A 186LEU A 441 | None | 1.01A | 1errB-4grxA:undetectable | 1errB-4grxA:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4htp | DNA LIGASE 4 (Homo sapiens) |
PF04675(DNA_ligase_A_N) | 5 | LEU A 152LEU A 221ILE A 203LEU A 194LEU A 186 | None | 1.03A | 1errB-4htpA:undetectable | 1errB-4htpA:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j5x | RETINOIC ACIDRECEPTOR RXR-ALPHA,NUCLEAR RECEPTORCOACTIVATOR 1 (Homo sapiens) |
no annotation | 5 | ALA D 272LEU D 276TRP D 305ARG D 316ILE D 428 | None | 1.01A | 1errB-4j5xD:22.7 | 1errB-4j5xD:29.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j5x | RETINOIC ACIDRECEPTOR RXR-ALPHA,NUCLEAR RECEPTORCOACTIVATOR 1 (Homo sapiens) |
no annotation | 5 | ALA D 272TRP D 305LEU D 309ARG D 316ILE D 428 | None | 0.91A | 1errB-4j5xD:22.7 | 1errB-4j5xD:29.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mv3 | BIOTIN CARBOXYLASE (Haemophilusinfluenzae) |
PF00289(Biotin_carb_N)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 5 | ALA A 386LEU A 388LEU A 15LEU A 357LEU A 406 | None | 1.13A | 1errB-4mv3A:undetectable | 1errB-4mv3A:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mwz | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE,PUTATIVE (Plasmodiumvivax) |
PF13649(Methyltransf_25) | 5 | THR A 41ALA A 40LEU A 210LEU A 213ILE A 27 | None | 1.04A | 1errB-4mwzA:undetectable | 1errB-4mwzA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mwz | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE,PUTATIVE (Plasmodiumvivax) |
PF13649(Methyltransf_25) | 5 | THR A 41ALA A 40TRP A 255LEU A 210LEU A 213 | None | 1.22A | 1errB-4mwzA:undetectable | 1errB-4mwzA:19.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4n1y | ESTROGEN RECEPTOR (Crassostreagigas) |
PF00104(Hormone_recep) | 6 | ALA A 287GLU A 290LEU A 291TRP A 320LEU A 324ARG A 331 | None | 0.50A | 1errB-4n1yA:26.9 | 1errB-4n1yA:38.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n77 | UNCHARACTERIZEDPROTEIN (Thermusthermophilus) |
PF09704(Cas_Cas5d) | 5 | ALA A 178LEU A 5LEU A 170LEU A 196LEU A 229 | None | 1.17A | 1errB-4n77A:undetectable | 1errB-4n77A:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nuf | MALTOSE ABCTRANSPORTERPERIPLASMIC PROTEIN,NUCLEAR RECEPTORSUBFAMILY 0 GROUP BMEMBER 2 CHIMERICCONSTRUCT (Escherichiacoli;Mus musculus) |
PF00104(Hormone_recep)PF13416(SBP_bac_8) | 6 | LEU A1091LEU A1098LEU A1101LEU A1076LEU A1257LEU A1259 | None | 1.42A | 1errB-4nufA:12.4 | 1errB-4nufA:17.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4phq | HEMOLYSIN E,CHROMOSOMAL (Escherichiacoli) |
PF06109(HlyE) | 5 | THR A 19ALA A 23LEU A 24TRP A 86LEU A 127 | None | 1.19A | 1errB-4phqA:undetectable | 1errB-4phqA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rgy | ESTERASE (unculturedbacterium FLS12) |
PF00756(Esterase) | 6 | ALA A 131LEU A 134LEU A 48LEU A 124ILE A 64LEU A 45 | None | 1.41A | 1errB-4rgyA:undetectable | 1errB-4rgyA:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4udb | MINERALOCORTICOIDRECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | ALA A 773TRP A 806LEU A 810LEU A 814ARG A 817 | CV7 A1987 (-3.5A)NoneCV7 A1987 (-4.0A)CV7 A1987 ( 4.0A)CV7 A1987 (-3.7A) | 0.47A | 1errB-4udbA:23.9 | 1errB-4udbA:26.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wzi | CAMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE 4B (Homo sapiens) |
PF00233(PDEase_I) | 5 | TRP A 348LEU A 421LEU A 422ILE A 371LEU A 645 | None | 1.15A | 1errB-4wziA:undetectable | 1errB-4wziA:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y0x | SERINE/THREONINE-PROTEIN KINASE PKNG (Mycobacteriumtuberculosis) |
PF00069(Pkinase)PF16919(PknG_rubred) | 5 | THR A 330LEU A 335ILE A 210LEU A 264LEU A 369 | None | 1.16A | 1errB-4y0xA:undetectable | 1errB-4y0xA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y0x | SERINE/THREONINE-PROTEIN KINASE PKNG (Mycobacteriumtuberculosis) |
PF00069(Pkinase)PF16919(PknG_rubred) | 5 | THR A 330LEU A 335ILE A 210LEU A 264LEU A 392 | None | 1.06A | 1errB-4y0xA:undetectable | 1errB-4y0xA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5amq | RNA POLYMERASE L (Californiaencephalitisorthobunyavirus) |
PF04196(Bunya_RdRp)PF15518(L_protein_N) | 6 | THR A1281ALA A1282LEU A1256LEU A1257LEU A1341LEU A1729 | None | 1.36A | 1errB-5amqA:undetectable | 1errB-5amqA:7.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b57 | HEMIN IMPORTATP-BINDING PROTEINHMUV (Burkholderiacenocepacia) |
PF00005(ABC_tran) | 5 | ALA C 223LEU C 195ILE C 249LEU C 33LEU C 179 | None | 1.19A | 1errB-5b57C:undetectable | 1errB-5b57C:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ep1 | PUTATIVE REPRESSORPROTEIN LUXO (Photobacteriumangustum) |
PF00158(Sigma54_activat) | 5 | GLU A 208LEU A 211LEU A 250LEU A 299LEU A 238 | None | 1.16A | 1errB-5ep1A:undetectable | 1errB-5ep1A:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iq0 | ESTERASE (unculturedbacterium) |
PF07859(Abhydrolase_3) | 5 | THR A 211ALA A 214GLU A 217ARG A 95LEU A 195 | None | 0.83A | 1errB-5iq0A:undetectable | 1errB-5iq0A:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kqw | 4-AMINOBUTYRATETRANSAMINASE (Pseudomonas) |
PF00202(Aminotran_3) | 5 | THR A 92ALA A 94GLU A 97LEU A 98LEU A 297 | None | 0.98A | 1errB-5kqwA:undetectable | 1errB-5kqwA:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5muw | PACKAGING ENZYME P4 (Pseudomonasvirus phi6) |
PF11602(NTPase_P4) | 5 | THR A 43ALA A 47GLU A 50LEU A 177LEU A 180 | None | 1.21A | 1errB-5muwA:undetectable | 1errB-5muwA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n28 | METHYL-COENZYME MREDUCTASE SUBUNITALPHAMETHYL-COENZYME MREDUCTASE, GAMMASUBUNIT (Methanotorrisformicicus) |
PF02240(MCR_gamma)PF02249(MCR_alpha)PF02745(MCR_alpha_N) | 5 | THR A 380LEU C 235LEU C 234ILE C 241LEU A 431 | None | 1.14A | 1errB-5n28A:undetectable | 1errB-5n28A:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nv8 | EF-P ARGININE 32RHAMNOSYL-TRANSFERASE (Pseudomonasputida) |
PF10093(DUF2331) | 5 | TRP A 338LEU A 324LEU A 321LEU A 205LEU A 202 | None | 1.05A | 1errB-5nv8A:undetectable | 1errB-5nv8A:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nzg | UDP-GLUCOSEPYROPHOSPHORYLASE (Leishmaniamajor) |
no annotation | 5 | THR A 307LEU A 259ILE A 194LEU A 310LEU A 58 | None | 1.19A | 1errB-5nzgA:undetectable | 1errB-5nzgA:17.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5op0 | DNA POLYMERASE LIGD,POLYMERASE DOMAIN (Mycolicibacteriumsmegmatis) |
no annotation | 5 | GLU B 206LEU B 203LEU B 163LEU B 185LEU B 137 | None | 0.97A | 1errB-5op0B:undetectable | 1errB-5op0B:17.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5toa | ESTROGEN RECEPTORBETA (Homo sapiens) |
PF00104(Hormone_recep) | 7 | ALA A 302GLU A 305TRP A 335LEU A 339LEU A 343ARG A 346ILE A 376 | EST A 601 ( 3.9A)EST A 601 (-2.4A)NoneEST A 601 (-3.9A)EST A 601 ( 4.4A)EST A 601 (-4.1A)EST A 601 ( 4.4A) | 0.50A | 1errB-5toaA:29.6 | 1errB-5toaA:57.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5toa | ESTROGEN RECEPTORBETA (Homo sapiens) |
PF00104(Hormone_recep) | 5 | ALA A 302GLU A 305TRP A 335LEU A 339LEU A 476 | EST A 601 ( 3.9A)EST A 601 (-2.4A)NoneEST A 601 (-3.9A)EST A 601 (-3.5A) | 0.66A | 1errB-5toaA:29.6 | 1errB-5toaA:57.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5toa | ESTROGEN RECEPTORBETA (Homo sapiens) |
PF00104(Hormone_recep) | 6 | GLU A 305TRP A 335LEU A 339LEU A 343ARG A 346LEU A 495 | EST A 601 (-2.4A)NoneEST A 601 (-3.9A)EST A 601 ( 4.4A)EST A 601 (-4.1A)None | 1.14A | 1errB-5toaA:29.6 | 1errB-5toaA:57.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5toa | ESTROGEN RECEPTORBETA (Homo sapiens) |
PF00104(Hormone_recep) | 7 | THR A 299ALA A 302GLU A 305TRP A 335LEU A 339LEU A 343ARG A 346 | NoneEST A 601 ( 3.9A)EST A 601 (-2.4A)NoneEST A 601 (-3.9A)EST A 601 ( 4.4A)EST A 601 (-4.1A) | 0.41A | 1errB-5toaA:29.6 | 1errB-5toaA:57.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5toa | ESTROGEN RECEPTORBETA (Homo sapiens) |
PF00104(Hormone_recep) | 6 | THR A 299GLU A 305LEU A 306TRP A 335LEU A 343ARG A 346 | NoneEST A 601 (-2.4A)NoneNoneEST A 601 ( 4.4A)EST A 601 (-4.1A) | 0.66A | 1errB-5toaA:29.6 | 1errB-5toaA:57.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v3e | TRANSCRIPTIONALREGULATOR (Porphyromonasgingivalis) |
no annotation | 5 | ALA A 65GLU A 66LEU A 110LEU A 52LEU A 90 | GOL A 201 (-3.7A)NoneNoneNoneNone | 0.86A | 1errB-5v3eA:undetectable | 1errB-5v3eA:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wbf | METHYL-ACCEPTINGCHEMOTAXISTRANSDUCER (TLPC) (Helicobacterpylori) |
no annotation | 5 | ALA A 117LEU A 102LEU A 94LEU A 95LEU A 70 | None | 1.02A | 1errB-5wbfA:undetectable | 1errB-5wbfA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zvt | C-TERMINUS OF OUTERCAPSID PROTEIN VP5 (Aquareovirus C) |
no annotation | 5 | THR B 442LEU B 351LEU B 349ILE B 307LEU B 358 | None | 1.09A | 1errB-5zvtB:undetectable | 1errB-5zvtB:14.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bk5 | UBIQUITIN LIGASE CBL (Salpingoecarosetta) |
no annotation | 5 | THR A 113ALA A 112LEU A 134ILE A 44LEU A 60 | None | 1.14A | 1errB-6bk5A:undetectable | 1errB-6bk5A:17.09 |