SIMILAR PATTERNS OF AMINO ACIDS FOR 1ERR_A_RALA600_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)

(Geobacillus
stearothermophilus) 		PF00342
(PGI) 		4 LEU A 376
LEU A 365
LEU A  19
LEU A  22
 None
 0.73A 1errA-1b0zA:
0.2		 1errA-1b0zA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dj3 ADENYLOSUCCINATE
SYNTHETASE

(Triticum
aestivum) 		PF00709
(Adenylsucc_synt) 		4 LEU A 279
LEU A 236
LEU A 269
LEU A 439
 None
 0.88A 1errA-1dj3A:
0.0		 1errA-1dj3A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e1k ADRENODOXIN
REDUCTASE

(Bos taurus) 		PF07992
(Pyr_redox_2) 		4 LEU A 164
LEU A 216
HIS A  55
LEU A 139
 None
None
FAD  A 801 ( 4.9A)
None
 0.67A 1errA-1e1kA:
undetectable		 1errA-1e1kA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f5a POLY(A) POLYMERASE

(Bos taurus) 		PF01909
(NTP_transf_2)
PF04926
(PAP_RNA-bind)
PF04928
(PAP_central) 		4 LEU A 105
HIS A 212
LEU A 190
LEU A 193
 None
 0.89A 1errA-1f5aA:
0.0		 1errA-1f5aA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ipk BETA-CONGLYCININ,
BETA CHAIN

(Glycine max) 		PF00190
(Cupin_1)
PF07883
(Cupin_2) 		4 LEU A 125
LEU A 244
LEU A 111
LEU A  62
 None
 0.93A 1errA-1ipkA:
undetectable		 1errA-1ipkA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j0n XANTHAN LYASE

(Bacillus sp.
GL1) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		4 LEU A 644
LEU A 401
LEU A 681
LEU A 679
 None
 0.91A 1errA-1j0nA:
0.4		 1errA-1j0nA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jsx GLUCOSE-INHIBITED
DIVISION PROTEIN B

(Escherichia
coli) 		PF02527
(GidB) 		4 LEU A  78
LEU A  83
LEU A  24
LEU A 199
 None
 0.84A 1errA-1jsxA:
0.8		 1errA-1jsxA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p4i ANTIBODY VARIABLE
HEAVY CHAIN
ANTIBODY VARIABLE
LIGHT CHAIN

(Mus musculus) 		PF07686
(V-set) 		4 LEU H 145
HIS L  50
LEU H  55
LEU H  74
 None
 0.90A 1errA-1p4iH:
undetectable		 1errA-1p4iH:
20.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pcg ESTROGEN RECEPTOR

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 LEU A 346
LEU A 387
LEU A 428
HIS A 524
 EST  A   1 (-4.4A)
EST  A   1 (-4.0A)
None
EST  A   1 (-3.8A)
 0.50A 1errA-1pcgA:
32.5		 1errA-1pcgA:
98.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (SMALL CHAIN)

(Synechococcus
elongatus) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N)
no annotation 		4 LEU A 390
LEU A 170
HIS A 383
LEU M  18
 None
 0.91A 1errA-1rblA:
undetectable		 1errA-1rblA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1taq TAQ DNA POLYMERASE

(Thermus
aquaticus) 		PF00476
(DNA_pol_A)
PF01367
(5_3_exonuc)
PF02739
(5_3_exonuc_N)
PF09281
(Taq-exonuc) 		4 LEU A  98
LEU A 273
LEU A  52
LEU A  55
 None
 0.91A 1errA-1taqA:
undetectable		 1errA-1taqA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wa5 IMPORTIN ALPHA
RE-EXPORTER

(Saccharomyces
cerevisiae) 		PF03378
(CAS_CSE1)
PF03810
(IBN_N)
PF08506
(Cse1) 		4 LEU C 788
LEU C 798
LEU C 767
LEU C 770
 None
 0.83A 1errA-1wa5C:
undetectable		 1errA-1wa5C:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cv6 SEED STORAGE PROTEIN

(Vigna radiata) 		PF00190
(Cupin_1) 		4 LEU A 130
LEU A 255
LEU A 116
LEU A  67
 None
 0.94A 1errA-2cv6A:
undetectable		 1errA-2cv6A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dbs HYPOTHETICAL PROTEIN
TTHC002

(Thermus
thermophilus) 		no annotation 4 LEU A  11
LEU A  39
LEU A  28
LEU A  25
 None
 0.92A 1errA-2dbsA:
undetectable		 1errA-2dbsA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f9r SPHINGOMYELINASE D 1

(Loxosceles
laeta) 		no annotation 4 LEU A  92
LEU A  97
LEU A  67
LEU A  70
 None
 0.91A 1errA-2f9rA:
undetectable		 1errA-2f9rA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2guu ODCASE

(Plasmodium
vivax) 		PF00215
(OMPdecase) 		4 LEU A 188
LEU A 140
LEU A 293
LEU A 320
 None
 0.90A 1errA-2guuA:
undetectable		 1errA-2guuA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ja2 GLUTAMYL-TRNA
SYNTHETASE

(Mycobacterium
tuberculosis) 		PF00749
(tRNA-synt_1c) 		4 LEU A 464
LEU A 368
LEU A 417
LEU A 414
 None
 0.92A 1errA-2ja2A:
undetectable		 1errA-2ja2A:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ocf ESTROGEN RECEPTOR

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 LEU A 346
LEU A 387
LEU A 428
HIS A 524
 EST  A 596 (-4.4A)
EST  A 596 ( 4.2A)
None
EST  A 596 (-4.2A)
 0.50A 1errA-2ocfA:
31.6		 1errA-2ocfA:
99.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p35 TRANS-ACONITATE
2-METHYLTRANSFERASE

(Agrobacterium
fabrum) 		PF13489
(Methyltransf_23) 		4 LEU A  37
LEU A 112
LEU A 119
LEU A 249
 None
 0.92A 1errA-2p35A:
undetectable		 1errA-2p35A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q6z UROPORPHYRINOGEN
DECARBOXYLASE

(Homo sapiens) 		PF01208
(URO-D) 		4 LEU A 131
LEU A 161
LEU A 248
LEU A 253
 None
 0.92A 1errA-2q6zA:
undetectable		 1errA-2q6zA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qj9 BONE MORPHOGENETIC
PROTEIN RECEPTOR
TYPE IA

(Homo sapiens) 		no annotation 4 LEU D 111
LEU D  73
HIS D  43
LEU D  36
 None
 0.85A 1errA-2qj9D:
undetectable		 1errA-2qj9D:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wfh SLIT HOMOLOG 2
PROTEIN C-PRODUCT

(Homo sapiens) 		PF01462
(LRRNT)
PF01463
(LRRCT)
PF13855
(LRR_8) 		4 LEU A 768
LEU A 784
LEU A 813
LEU A 779
 None
 0.79A 1errA-2wfhA:
undetectable		 1errA-2wfhA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xa2 TREHALOSE-SYNTHASE
TRET

(Pyrococcus
horikoshii) 		PF00534
(Glycos_transf_1) 		4 LEU A 169
HIS A  92
LEU A  59
LEU A  62
 None
UPG  A1415 (-4.6A)
None
None
 0.94A 1errA-2xa2A:
undetectable		 1errA-2xa2A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xt6 2-OXOGLUTARATE
DECARBOXYLASE

(Mycolicibacterium
smegmatis) 		PF00198
(2-oxoacid_dh)
PF00676
(E1_dh)
PF02779
(Transket_pyr)
PF16870
(OxoGdeHyase_C) 		4 LEU A1094
LEU A1051
LEU A1184
LEU A1195
 None
 0.91A 1errA-2xt6A:
undetectable		 1errA-2xt6A:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xwg SORTASE

(Actinomyces
oris) 		PF04203
(Sortase) 		4 LEU A 167
LEU A 201
LEU A 216
LEU A 230
 None
 0.94A 1errA-2xwgA:
undetectable		 1errA-2xwgA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y3a PHOSPHATIDYLINOSITOL
-4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT BETA ISOFORM

(Mus musculus) 		PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka)
PF00792
(PI3K_C2)
PF00794
(PI3K_rbd)
PF02192
(PI3K_p85B) 		4 LEU A 634
LEU A 997
LEU A1009
LEU A 820
 None
 0.90A 1errA-2y3aA:
1.9		 1errA-2y3aA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ych COMPETENCE PROTEIN
PILM

(Thermus
thermophilus) 		PF11104
(PilM_2) 		4 LEU A 214
LEU A 194
LEU A 185
LEU A 219
 None
 0.80A 1errA-2ychA:
undetectable		 1errA-2ychA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yys PROLINE
IMINOPEPTIDASE-RELAT
ED PROTEIN

(Thermus
thermophilus) 		PF12697
(Abhydrolase_6) 		4 LEU A 284
LEU A 276
LEU A 113
LEU A 110
 None
GOL  A 501 ( 3.6A)
None
None
 0.93A 1errA-2yysA:
undetectable		 1errA-2yysA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3byw PUTATIVE
ARABINOFURANOSYLTRAN
SFERASE

(Corynebacterium
diphtheriae) 		PF04602
(Arabinose_trans) 		4 LEU A 100
LEU A  88
LEU A  83
LEU A  57
 None
 0.84A 1errA-3bywA:
undetectable		 1errA-3bywA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cqg NUCLEAR PORE COMPLEX
PROTEIN NUP107

(Homo sapiens) 		PF04121
(Nup84_Nup100) 		4 LEU A 875
LEU A 865
LEU A 821
LEU A 822
 None
 0.83A 1errA-3cqgA:
undetectable		 1errA-3cqgA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3k ENHANCER OF
MRNA-DECAPPING
PROTEIN 3

(Homo sapiens) 		PF03853
(YjeF_N) 		4 LEU A 411
LEU A 339
LEU A 399
LEU A 305
 None
 0.88A 1errA-3d3kA:
undetectable		 1errA-3d3kA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3db1 STS-2 PROTEIN

(Mus musculus) 		PF00300
(His_Phos_1) 		4 LEU A 547
LEU A 583
LEU A 495
LEU A 492
 None
 0.86A 1errA-3db1A:
undetectable		 1errA-3db1A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dxq CHOLINE/ETHANOLAMINE
KINASE FAMILY
PROTEIN

(Mesorhizobium
loti) 		PF01633
(Choline_kinase) 		4 LEU A 284
LEU A 294
LEU A 255
LEU A 258
 None
 0.87A 1errA-3dxqA:
undetectable		 1errA-3dxqA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e7o MITOGEN-ACTIVATED
PROTEIN KINASE 9

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 165
LEU A 168
LEU A 152
LEU A  89
 None
35F  A   1 (-4.5A)
None
None
 0.74A 1errA-3e7oA:
undetectable		 1errA-3e7oA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fgq NEUROSERPIN

(Homo sapiens) 		PF00079
(Serpin) 		4 LEU A  55
LEU A  62
LEU A 112
LEU A  81
 None
 0.91A 1errA-3fgqA:
undetectable		 1errA-3fgqA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hc1 UNCHARACTERIZED HDOD
DOMAIN PROTEIN

(Geobacter
sulfurreducens) 		PF08668
(HDOD) 		4 LEU A 105
LEU A 149
LEU A 205
LEU A  66
 GOL  A 312 (-4.3A)
None
None
None
 0.81A 1errA-3hc1A:
1.9		 1errA-3hc1A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hd8 XYLANASE INHIBITOR

(Triticum
aestivum) 		PF14541
(TAXi_C)
PF14543
(TAXi_N) 		4 LEU A 374
LEU A 360
LEU A 306
LEU A 304
 None
 0.92A 1errA-3hd8A:
undetectable		 1errA-3hd8A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3naf CALCIUM-ACTIVATED
POTASSIUM CHANNEL
SUBUNIT
ALPHA-1,CALCIUM-ACTI
VATED POTASSIUM
CHANNEL SUBUNIT
ALPHA-1,CALCIUM-ACTI
VATED POTASSIUM
CHANNEL SUBUNIT
ALPHA-1

(Homo sapiens) 		PF03493
(BK_channel_a) 		4 LEU A 425
LEU A 461
LEU A 387
LEU A 390
 None
 0.89A 1errA-3nafA:
undetectable		 1errA-3nafA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3naw SECRETED EFFECTOR
PROTEIN

(Escherichia
coli) 		PF00805
(Pentapeptide)
PF13979
(SopA_C)
PF13981
(SopA) 		4 LEU A 454
LEU A 425
HIS A 413
LEU A 365
 None
 0.78A 1errA-3nawA:
undetectable		 1errA-3nawA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oja ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1

(Anopheles
gambiae) 		PF13855
(LRR_8) 		5 LEU B 466
LEU B 518
HIS B 460
LEU B 420
LEU B 422
 None
 1.49A 1errA-3ojaB:
undetectable		 1errA-3ojaB:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oqc UFM1-SPECIFIC
PROTEASE 2

(Mus musculus) 		PF07910
(Peptidase_C78) 		4 LEU A 205
LEU A 215
LEU A  33
LEU A  36
 None
 0.87A 1errA-3oqcA:
undetectable		 1errA-3oqcA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE

(Pseudomonas
aeruginosa) 		PF01048
(PNP_UDP_1) 		4 LEU A  62
LEU A  32
LEU A 213
LEU A 211
 None
 0.88A 1errA-3ozbA:
undetectable		 1errA-3ozbA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p8l GERANYLTRANSTRANSFER
ASE

(Enterococcus
faecalis) 		PF00348
(polyprenyl_synt) 		4 LEU A 180
LEU A  79
LEU A 290
LEU A 287
 None
 0.77A 1errA-3p8lA:
undetectable		 1errA-3p8lA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p94 GDSL-LIKE LIPASE

(Parabacteroides
distasonis) 		PF13472
(Lipase_GDSL_2) 		4 LEU A 104
LEU A 126
LEU A 195
LEU A 199
 None
 0.69A 1errA-3p94A:
undetectable		 1errA-3p94A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qcw NEUREXIN-1-ALPHA

(Bos taurus) 		PF00008
(EGF)
PF02210
(Laminin_G_2) 		4 LEU A 811
LEU A 762
LEU A 830
LEU A1069
 None
 0.84A 1errA-3qcwA:
undetectable		 1errA-3qcwA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qit POLYKETIDE SYNTHASE

(Moorea
producens) 		PF00561
(Abhydrolase_1) 		4 LEU A  79
HIS A  61
LEU A  96
LEU A 120
 None
 0.70A 1errA-3qitA:
undetectable		 1errA-3qitA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qzy BACULOVIRUS
SULFHYDRYL OXIDASE
AC92

(Autographa
californica
multiple
nucleopolyhedrovirus) 		PF05214
(Baculo_p33) 		4 LEU A  22
LEU A 116
LEU A  94
LEU A  92
 None
 0.91A 1errA-3qzyA:
undetectable		 1errA-3qzyA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t1p ALPHA-1-ANTITRYPSIN

(Homo sapiens) 		PF00079
(Serpin) 		4 LEU A 353
LEU A 172
LEU A  80
LEU A  77
 None
 0.86A 1errA-3t1pA:
undetectable		 1errA-3t1pA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vm5 ALPHA-AMYLASE

(Oryzias latipes) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C) 		4 LEU A 170
HIS A 101
LEU A  69
LEU A  79
 None
 0.94A 1errA-3vm5A:
undetectable		 1errA-3vm5A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wpe TOLL-LIKE RECEPTOR 9

(Bos taurus) 		PF13516
(LRR_6)
PF13855
(LRR_8) 		4 LEU A 663
HIS A 645
LEU A 628
LEU A 598
 None
 0.78A 1errA-3wpeA:
undetectable		 1errA-3wpeA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wxo CATALASE-PEROXIDASE

(Synechococcus
elongatus) 		PF00141
(peroxidase) 		4 LEU A 527
LEU A 546
LEU A 615
LEU A 612
 None
 0.88A 1errA-3wxoA:
undetectable		 1errA-3wxoA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE

(Flaveria
pringlei) 		PF00311
(PEPcase) 		4 LEU A 149
LEU A 693
LEU A 651
LEU A 262
 None
 0.84A 1errA-3zgbA:
2.6		 1errA-3zgbA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bq4 B-AGARASE

(Saccharophagus
degradans) 		PF02449
(Glyco_hydro_42) 		4 LEU A 426
LEU A 398
LEU A 276
LEU A 279
 None
 0.74A 1errA-4bq4A:
undetectable		 1errA-4bq4A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4htz CGMP-DEPENDENT
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF00233
(PDEase_I) 		4 LEU A 809
LEU A 802
HIS A 696
LEU A 677
 None
None
ZN  A1001 (-3.4A)
None
 0.88A 1errA-4htzA:
undetectable		 1errA-4htzA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iv5 ASPARTATE
CARBAMOYLTRANSFERASE
, PUTATIVE

(Trypanosoma
cruzi) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 LEU A 132
LEU A 124
LEU A  29
LEU A  32
 None
 0.94A 1errA-4iv5A:
undetectable		 1errA-4iv5A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kng LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 5

(Homo sapiens) 		PF00560
(LRR_1)
PF01462
(LRRNT)
PF13855
(LRR_8) 		4 LEU A 405
LEU A 434
LEU A 400
LEU A 376
 None
 0.92A 1errA-4kngA:
undetectable		 1errA-4kngA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kp2 HOMOACONITASE LARGE
SUBUNIT

(Methanocaldococcus
jannaschii) 		PF00330
(Aconitase) 		4 LEU A 380
LEU A 373
HIS A 278
LEU A 173
 None
 0.86A 1errA-4kp2A:
undetectable		 1errA-4kp2A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kqn D-HYDANTOINASE

(Bacillus sp.
AR9) 		PF01979
(Amidohydro_1) 		4 LEU A 270
LEU A 404
LEU A 304
LEU A 309
 LEU  A 270 ( 0.6A)
LEU  A 404 ( 0.6A)
LEU  A 304 ( 0.6A)
LEU  A 309 ( 0.6A)
 0.57A 1errA-4kqnA:
undetectable		 1errA-4kqnA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kry ACETYL ESTERASE

(Escherichia
coli) 		PF07859
(Abhydrolase_3) 		4 LEU A 170
LEU A 229
LEU A 247
LEU A 275
 None
 0.87A 1errA-4kryA:
undetectable		 1errA-4kryA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mtl PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21C

(Homo sapiens) 		PF10294
(Methyltransf_16) 		4 LEU A 117
LEU A 149
LEU A 256
LEU A 246
 None
 0.94A 1errA-4mtlA:
undetectable		 1errA-4mtlA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ppm AMINOTRANSFERASE

(Serratia sp.
FS14) 		PF00202
(Aminotran_3) 		4 LEU A 613
LEU A 663
LEU A 568
LEU A 565
 None
 0.83A 1errA-4ppmA:
undetectable		 1errA-4ppmA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r0m MCYG PROTEIN

(Microcystis
aeruginosa) 		no annotation 4 LEU B 179
LEU B  75
LEU B  62
LEU B  59
 None
 0.90A 1errA-4r0mB:
undetectable		 1errA-4r0mB:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r10 PROTEIN HUMPBACK-2

(Caenorhabditis
elegans) 		PF00514
(Arm) 		4 LEU A 233
LEU A 210
LEU A 246
LEU A 165
 None
 0.83A 1errA-4r10A:
undetectable		 1errA-4r10A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4trq NUCLEAR MRNA EXPORT
PROTEIN SAC3

(Saccharomyces
cerevisiae) 		PF03399
(SAC3_GANP) 		4 LEU A 544
LEU A 532
LEU A 342
LEU A 345
 None
 0.86A 1errA-4trqA:
undetectable		 1errA-4trqA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ufs LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 5

(Homo sapiens) 		PF00560
(LRR_1)
PF01462
(LRRNT)
PF13855
(LRR_8) 		4 LEU A 217
LEU A 246
LEU A 212
LEU A 188
 None
 0.93A 1errA-4ufsA:
undetectable		 1errA-4ufsA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4um8 INTEGRIN BETA-6

(Homo sapiens) 		PF00362
(Integrin_beta)
PF17205
(PSI_integrin) 		4 LEU B 423
LEU B 360
LEU B 429
LEU B  92
 None
 0.90A 1errA-4um8B:
undetectable		 1errA-4um8B:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v2e FIBRONECTIN LEUCINE
RICH TRANSMEMBRANE
PROTEIN 3

(Mus musculus) 		PF01462
(LRRNT)
PF13855
(LRR_8) 		4 LEU A 254
LEU A 283
LEU A 249
LEU A 227
 None
 0.93A 1errA-4v2eA:
undetectable		 1errA-4v2eA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yg8 CHITIN BIOSYNTHESIS
PROTEIN CHS6

(Saccharomyces
cerevisiae) 		PF09295
(ChAPs) 		4 LEU B 734
LEU B 697
LEU B 678
LEU B 264
 None
 0.77A 1errA-4yg8B:
undetectable		 1errA-4yg8B:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5awm STRESS-ACTIVATED
PROTEIN KINASE JNK

(Drosophila
melanogaster) 		PF00069
(Pkinase) 		4 LEU A 163
LEU A 166
LEU A 150
LEU A  87
 None
ANP  A 401 ( 4.5A)
None
None
 0.87A 1errA-5awmA:
undetectable		 1errA-5awmA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dsy POLY [ADP-RIBOSE]
POLYMERASE 2

(Homo sapiens) 		PF00644
(PARP) 		4 LEU A 412
HIS A 415
LEU A 391
LEU A 359
 None
UHB  A1001 (-3.7A)
None
None
 0.88A 1errA-5dsyA:
undetectable		 1errA-5dsyA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5elt KH
DOMAIN-CONTAINING,
RNA-BINDING, SIGNAL
TRANSDUCTION-ASSOCIA
TED PROTEIN 3

(Homo sapiens) 		no annotation 4 LEU B  56
LEU B 148
LEU B  87
LEU B  84
 None
None
None
A  E   2 ( 4.8A)
 0.85A 1errA-5eltB:
undetectable		 1errA-5eltB:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5elx ATP-DEPENDENT RNA
HELICASE DBP5

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 LEU A 390
LEU A 364
LEU A 321
LEU A 324
 None
 0.74A 1errA-5elxA:
undetectable		 1errA-5elxA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f1z NON-RECEPTOR
TYROSINE-PROTEIN
KINASE TYK2

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 LEU A1024
LEU A1165
LEU A1128
LEU A1124
 None
 0.94A 1errA-5f1zA:
undetectable		 1errA-5f1zA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fwj HISTONE DEMETHYLASE
JARID1C

(Homo sapiens) 		PF02373
(JmjC)
PF02375
(JmjN)
PF02928
(zf-C5HC2) 		4 LEU A 716
LEU A 747
LEU A 760
LEU A 763
 None
 0.93A 1errA-5fwjA:
undetectable		 1errA-5fwjA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5p NUCLEAR MRNA EXPORT
PROTEIN SAC3

(Saccharomyces
cerevisiae) 		PF03399
(SAC3_GANP) 		4 LEU A 544
LEU A 532
LEU A 342
LEU A 345
 None
 0.94A 1errA-5g5pA:
undetectable		 1errA-5g5pA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo sapiens) 		PF03071
(GNT-I)
PF15711
(ILEI) 		4 LEU A 622
LEU A 555
HIS A 573
LEU A 439
 None
 0.89A 1errA-5gggA:
undetectable		 1errA-5gggA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gje LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 6

(Homo sapiens) 		PF00058
(Ldl_recept_b)
PF14670
(FXa_inhibition) 		4 LEU A  81
LEU A 105
LEU A 170
LEU A 177
 None
 0.73A 1errA-5gjeA:
undetectable		 1errA-5gjeA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gsl 778AA LONG
HYPOTHETICAL
BETA-GALACTOSIDASE

(Pyrococcus
horikoshii) 		PF02449
(Glyco_hydro_42) 		4 LEU A 481
LEU A 645
LEU A 369
LEU A 365
 None
 0.89A 1errA-5gslA:
undetectable		 1errA-5gslA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gsm EXO-BETA-D-GLUCOSAMI
NIDASE

(Thermococcus
kodakarensis) 		PF02449
(Glyco_hydro_42) 		4 LEU A 443
LEU A 504
LEU A 478
LEU A 549
 PPI  A 808 (-4.0A)
None
None
None
 0.69A 1errA-5gsmA:
undetectable		 1errA-5gsmA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gwo PROBABLE PROTEIN
PHOSPHATASE 2C 50

(Oryza sativa) 		PF00481
(PP2C) 		4 LEU A 109
LEU A 207
LEU A  97
LEU A 100
 None
 0.78A 1errA-5gwoA:
undetectable		 1errA-5gwoA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hl3 LMO2470 PROTEIN

(Listeria
monocytogenes) 		PF00560
(LRR_1)
PF12354
(Internalin_N)
PF13855
(LRR_8) 		4 LEU A 226
LEU A 253
LEU A 221
LEU A 199
 None
 0.93A 1errA-5hl3A:
undetectable		 1errA-5hl3A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hlb PENICILLIN-BINDING
PROTEIN 1B

(Escherichia
coli) 		PF00905
(Transpeptidase)
PF00912
(Transgly)
PF14814
(UB2H) 		4 LEU A 229
LEU A 316
LEU A 394
LEU A 390
 None
 0.80A 1errA-5hlbA:
undetectable		 1errA-5hlbA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hz1 PROBABLE LRR
RECEPTOR-LIKE
SERINE/THREONINE-PRO
TEIN KINASE
AT4G26540

(Arabidopsis
thaliana) 		PF13855
(LRR_8) 		4 LEU B  98
LEU B 143
LEU B 105
LEU B  84
 None
 0.90A 1errA-5hz1B:
undetectable		 1errA-5hz1B:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iu9 PROTOCADHERIN-19
ISOFORM 1

(Danio rerio) 		PF00028
(Cadherin)
PF08266
(Cadherin_2) 		4 LEU A 373
LEU A 398
LEU A 325
LEU A 388
 None
 0.91A 1errA-5iu9A:
undetectable		 1errA-5iu9A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k3h ACYL-COENZYME A
OXIDASE

(Caenorhabditis
elegans) 		PF01756
(ACOX)
PF02770
(Acyl-CoA_dh_M)
PF14749
(Acyl-CoA_ox_N) 		4 LEU A 310
LEU A 625
LEU A 566
LEU A 569
 None
 0.93A 1errA-5k3hA:
2.1		 1errA-5k3hA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kzs PUTATIVE CELL
SURFACE PROTEIN,
SIMILAR TO
INTERNALIN PROTEINS

(Listeria
monocytogenes) 		PF12354
(Internalin_N)
PF13855
(LRR_8) 		4 LEU A 204
LEU A 231
LEU A 199
LEU A 175
 None
 0.94A 1errA-5kzsA:
undetectable		 1errA-5kzsA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l3t NUCLEAR MRNA EXPORT
PROTEIN SAC3

(Saccharomyces
cerevisiae) 		PF03399
(SAC3_GANP) 		4 LEU A 544
LEU A 532
LEU A 342
LEU A 345
 None
 0.94A 1errA-5l3tA:
undetectable		 1errA-5l3tA:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lly DIGUANYLATE CYCLASE
(GGDEF)
DOMAIN-CONTAINING
PROTEIN

(Idiomarina sp.
A28L) 		no annotation 4 LEU D  35
LEU D 226
LEU D  65
HIS D 230
 None
 0.90A 1errA-5llyD:
undetectable		 1errA-5llyD:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m6u PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka)
PF00792
(PI3K_C2)
PF00794
(PI3K_rbd)
PF02192
(PI3K_p85B) 		4 LEU A 613
LEU A 977
LEU A 989
LEU A 800
 None
 0.90A 1errA-5m6uA:
undetectable		 1errA-5m6uA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mpd 26S PROTEASOME
REGULATORY SUBUNIT
RPN12
26S PROTEASOME
REGULATORY SUBUNIT
RPN3

(Saccharomyces
cerevisiae) 		PF01399
(PCI)
PF08375
(Rpn3_C)
PF10075
(CSN8_PSD8_EIF3K) 		4 LEU S 372
HIS T 132
LEU T 110
LEU T 113
 None
 0.88A 1errA-5mpdS:
undetectable		 1errA-5mpdS:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mx0 FIBROMODULIN

(Homo sapiens) 		PF01462
(LRRNT)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 LEU A 207
LEU A 235
LEU A 202
LEU A 178
 None
 0.88A 1errA-5mx0A:
undetectable		 1errA-5mx0A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nfu SERINE/THREONINE-PRO
TEIN KINASE PLK1

(Homo sapiens) 		no annotation 4 LEU A 591
LEU A 381
LEU A 511
LEU A 435
 None
 0.86A 1errA-5nfuA:
undetectable		 1errA-5nfuA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ohs -

(-) 		no annotation 4 LEU A 474
HIS A 576
LEU A 622
LEU A 660
 None
 0.93A 1errA-5ohsA:
undetectable		 1errA-5ohsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oqr CONDENSIN COMPLEX
SUBUNIT 2
CONDENSIN COMPLEX
SUBUNIT 3

(Schizosaccharomyces
pombe) 		no annotation 4 LEU A 504
LEU A 551
LEU A 522
LEU C 531
 None
 0.85A 1errA-5oqrA:
undetectable		 1errA-5oqrA:
15.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5toa ESTROGEN RECEPTOR
BETA

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 LEU A 298
LEU A 339
LEU A 380
HIS A 475
 EST  A 601 (-4.1A)
EST  A 601 (-3.9A)
None
EST  A 601 (-4.4A)
 0.45A 1errA-5toaA:
29.8		 1errA-5toaA:
57.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ubp LEUCINE PERMEASE
TRANSCRIPTIONAL
REGULATOR

(Saccharomyces
cerevisiae) 		PF03399
(SAC3_GANP) 		4 LEU A 544
LEU A 532
LEU A 342
LEU A 345
 None
 0.91A 1errA-5ubpA:
undetectable		 1errA-5ubpA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ue0 CT622 PROTEIN

(Chlamydia
trachomatis) 		no annotation 4 LEU A 558
LEU A 639
LEU A 548
LEU A 515
 None
 0.91A 1errA-5ue0A:
undetectable		 1errA-5ue0A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vbu CYTOCHROME P450
21-HYDROXYLASE

(Homo sapiens) 		PF00067
(p450) 		4 LEU A 216
LEU A 224
HIS A 204
LEU A  38
 None
 0.77A 1errA-5vbuA:
undetectable		 1errA-5vbuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wdi UBIQUITIN-ASSOCIATED
AND SH3
DOMAIN-CONTAINING
PROTEIN A

(Homo sapiens) 		PF00300
(His_Phos_1) 		4 LEU A 584
LEU A 620
LEU A 532
LEU A 529
 None
 0.78A 1errA-5wdiA:
undetectable		 1errA-5wdiA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c8q NH(3)-DEPENDENT
NAD(+) SYNTHETASE

(Enterococcus
faecalis) 		no annotation 4 LEU A 185
LEU A 200
LEU A  35
LEU A  41
 None
 0.84A 1errA-6c8qA:
undetectable		 1errA-6c8qA:
15.14