SIMILAR PATTERNS OF AMINO ACIDS FOR 1EJ0_A_SAMA301_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1amy 1,4-ALPHA-D-GLUCAN
GLUCANOHYDROLASE

(Hordeum vulgare) 		PF00128
(Alpha-amylase)
PF07821
(Alpha-amyl_C2) 		3 ASP A 396
ASP A 302
ASP A 360
 None
 0.68A 1ej0A-1amyA:
undetectable		 1ej0A-1amyA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c30 CARBAMOYL PHOSPHATE
SYNTHETASE: LARGE
SUBUNIT

(Escherichia
coli) 		PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3) 		3 ASP A 128
ASP A 121
ASP A 133
 None
None
K  A4019 ( 4.6A)
 0.77A 1ej0A-1c30A:
4.7		 1ej0A-1c30A:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ckm MRNA CAPPING ENZYME

(Paramecium
bursaria
Chlorella virus
1) 		PF01331
(mRNA_cap_enzyme)
PF03919
(mRNA_cap_C) 		3 ASP A  45
ASP A  49
ASP A  38
 None
 0.64A 1ej0A-1ckmA:
undetectable		 1ej0A-1ckmA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d0n HORSE PLASMA
GELSOLIN

(Equus caballus) 		PF00626
(Gelsolin) 		3 ASP A 670
ASP A 687
ASP A 665
 None
 0.76A 1ej0A-1d0nA:
undetectable		 1ej0A-1d0nA:
14.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1eiz FTSJ

(Escherichia
coli) 		PF01728
(FtsJ) 		3 ASP A  83
ASP A  99
ASP A 124
 SAM  A 301 (-2.8A)
SAM  A 301 (-3.5A)
SAM  A 301 (-3.6A)
 0.08A 1ej0A-1eizA:
36.9		 1ej0A-1eizA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ezw COENZYME
F420-DEPENDENT
N5,N10-METHYLENETETR
AHYDROMETHANOPTERIN
REDUCTASE

(Methanopyrus
kandleri) 		PF00296
(Bac_luciferase) 		3 ASP A 303
ASP A 239
ASP A 309
 None
 0.65A 1ej0A-1ezwA:
undetectable		 1ej0A-1ezwA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ioo SF11-RNASE

(Nicotiana alata) 		PF00445
(Ribonuclease_T2) 		3 ASP A 113
ASP A 116
ASP A  62
 NAG  A 198 ( 3.5A)
NAG  A 197 (-3.7A)
XYP  A 200 ( 4.6A)
 0.69A 1ej0A-1iooA:
undetectable		 1ej0A-1iooA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jxi PHOSPHOMETHYLPYRIMID
INE KINASE

(Salmonella
enterica) 		PF08543
(Phos_pyr_kin) 		3 ASP A  58
ASP A  65
ASP A  85
 None
 0.76A 1ej0A-1jxiA:
3.4		 1ej0A-1jxiA:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k9x M32 CARBOXYPEPTIDASE

(Pyrococcus
furiosus) 		PF02074
(Peptidase_M32) 		3 ASP A 171
ASP A 161
ASP A 484
 None
 0.72A 1ej0A-1k9xA:
undetectable		 1ej0A-1k9xA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lss TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKA
HOMOLOG

(Methanocaldococcus
jannaschii) 		PF02254
(TrkA_N) 		3 ASP A  30
ASP A  34
ASP A  51
 NAD  A1001 (-2.9A)
None
NAD  A1001 (-3.3A)
 0.66A 1ej0A-1lssA:
8.5		 1ej0A-1lssA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mi8 DNAB INTEIN

(Synechocystis
sp. PCC 6803) 		PF14890
(Intein_splicing) 		3 ASP A  21
ASP A  24
ASP A   5
 None
 0.71A 1ej0A-1mi8A:
undetectable		 1ej0A-1mi8A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ne2 HYPOTHETICAL PROTEIN
TA1320

(Thermoplasma
acidophilum) 		PF06325
(PrmA) 		3 ASP A  78
ASP A  82
ASP A 100
 None
 0.69A 1ej0A-1ne2A:
13.1		 1ej0A-1ne2A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nw5 MODIFICATION
METHYLASE RSRI

(Rhodobacter
sphaeroides) 		PF01555
(N6_N4_Mtase) 		3 ASP A 271
ASP A  46
ASP A  65
 SAM  A 401 (-2.9A)
SAM  A 401 (-3.6A)
SAM  A 401 (-3.3A)
 0.59A 1ej0A-1nw5A:
3.1		 1ej0A-1nw5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p5s RAS
GTPASE-ACTIVATING-LI
KE PROTEIN RNG2

(Schizosaccharomyces
pombe) 		PF00307
(CH) 		3 ASP A  45
ASP A 169
ASP A 160
 None
 0.77A 1ej0A-1p5sA:
undetectable		 1ej0A-1p5sA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pp0 VOLVATOXIN A2

(Volvariella
volvacea) 		PF01338
(Bac_thur_toxin) 		3 ASP A  64
ASP A  61
ASP A  88
 None
 0.77A 1ej0A-1pp0A:
undetectable		 1ej0A-1pp0A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qb4 PHOSPHOENOLPYRUVATE
CARBOXYLASE

(Escherichia
coli) 		PF00311
(PEPcase) 		3 ASP A 510
ASP A 543
ASP A 482
 None
MN  A 885 (-3.0A)
None
 0.79A 1ej0A-1qb4A:
undetectable		 1ej0A-1qb4A:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s6j CALCIUM-DEPENDENT
PROTEIN KINASE SK5

(Glycine max) 		PF13499
(EF-hand_7) 		3 ASP A  33
ASP A  47
ASP A  77
 CA  A  88 (-3.0A)
None
CA  A  89 (-4.3A)
 0.79A 1ej0A-1s6jA:
undetectable		 1ej0A-1s6jA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1taq TAQ DNA POLYMERASE

(Thermus
aquaticus) 		PF00476
(DNA_pol_A)
PF01367
(5_3_exonuc)
PF02739
(5_3_exonuc_N)
PF09281
(Taq-exonuc) 		3 ASP A 120
ASP A 251
ASP A 144
 None
 0.67A 1ej0A-1taqA:
undetectable		 1ej0A-1taqA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ve3 HYPOTHETICAL PROTEIN
PH0226

(Pyrococcus
horikoshii) 		PF13649
(Methyltransf_25) 		3 ASP A  67
ASP A  71
ASP A  93
 SAM  A 302 (-2.8A)
None
SAM  A 302 (-3.4A)
 0.68A 1ej0A-1ve3A:
11.6		 1ej0A-1ve3A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vl5 UNKNOWN CONSERVED
PROTEIN BH2331

(Bacillus
halodurans) 		PF08241
(Methyltransf_11) 		3 ASP A  71
ASP A  75
ASP A  98
 None
 0.78A 1ej0A-1vl5A:
13.0		 1ej0A-1vl5A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wk1 HYPOTHETICAL PROTEIN
YK1067A12

(Caenorhabditis
elegans) 		PF00059
(Lectin_C) 		3 ASP A 117
ASP A  95
ASP A 104
 None
 0.68A 1ej0A-1wk1A:
undetectable		 1ej0A-1wk1A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 ASP A 509
ASP A 323
ASP A 501
 None
 0.65A 1ej0A-1xkhA:
undetectable		 1ej0A-1xkhA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yo6 PUTATIVE CARBONYL
REDUCTASE SNIFFER

(Caenorhabditis
elegans) 		PF00106
(adh_short) 		3 ASP A 192
ASP A 138
ASP A 189
 None
 0.60A 1ej0A-1yo6A:
9.6		 1ej0A-1yo6A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yr2 PROLYL
OLIGOPEPTIDASE

(Novosphingobium
capsulatum) 		PF00326
(Peptidase_S9)
PF02897
(Peptidase_S9_N) 		3 ASP A 172
ASP A 220
ASP A 278
 None
 0.65A 1ej0A-1yr2A:
2.5		 1ej0A-1yr2A:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2acv TRITERPENE
UDP-GLUCOSYL
TRANSFERASE UGT71G1

(Medicago
truncatula) 		PF00201
(UDPGT) 		3 ASP A 166
ASP A 168
ASP A 190
 None
 0.79A 1ej0A-2acvA:
3.8		 1ej0A-2acvA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b9e NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2

(Homo sapiens) 		PF01189
(Methyltr_RsmB-F) 		3 ASP A 258
ASP A 285
ASP A 305
 SAM  A1201 (-2.6A)
SAM  A1201 (-3.6A)
SAM  A1201 (-3.7A)
 0.65A 1ej0A-2b9eA:
13.2		 1ej0A-2b9eA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dul N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE

(Pyrococcus
horikoshii) 		PF02005
(TRM) 		3 ASP A  78
ASP A  82
ASP A 120
 None
 0.69A 1ej0A-2dulA:
9.7		 1ej0A-2dulA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kma TALIN 1

(Mus musculus) 		PF09379
(FERM_N)
PF16511
(FERM_f0) 		3 ASP A  77
ASP A  69
ASP A  53
 None
 0.66A 1ej0A-2kmaA:
undetectable		 1ej0A-2kmaA:
20.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2nyu PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2

(Homo sapiens) 		PF01728
(FtsJ) 		3 ASP A  62
ASP A  79
ASP A 104
 SAM  A 201 (-2.8A)
SAM  A 201 (-3.3A)
SAM  A 201 (-3.7A)
 0.42A 1ej0A-2nyuA:
26.3		 1ej0A-2nyuA:
36.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oka HYPOTHETICAL PROTEIN

(Pseudomonas
aeruginosa) 		PF10262
(Rdx) 		3 ASP A  83
ASP A  35
ASP A  87
 None
 0.75A 1ej0A-2okaA:
undetectable		 1ej0A-2okaA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pg8 DPGC

(Streptomyces
toyocaensis) 		PF00378
(ECH_1) 		3 ASP A 195
ASP A 202
ASP A 249
 None
 0.62A 1ej0A-2pg8A:
undetectable		 1ej0A-2pg8A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qvs CAMP-DEPENDENT
PROTEIN KINASE TYPE
II-ALPHA REGULATORY
SUBUNIT

(Mus musculus) 		PF00027
(cNMP_binding) 		3 ASP B 181
ASP B 197
ASP B 159
 ASP  B 181 ( 0.5A)
ASP  B 197 ( 0.6A)
ASP  B 159 ( 0.5A)
 0.70A 1ej0A-2qvsB:
undetectable		 1ej0A-2qvsB:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vrn PROTEASE I

(Deinococcus
radiodurans) 		PF01965
(DJ-1_PfpI) 		3 ASP A  77
ASP A 184
ASP A  75
 None
 0.77A 1ej0A-2vrnA:
2.7		 1ej0A-2vrnA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xmr PROTEIN NDRG2

(Homo sapiens) 		PF03096
(Ndr) 		3 ASP A 158
ASP A 228
ASP A 255
 None
 0.61A 1ej0A-2xmrA:
2.5		 1ej0A-2xmrA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE

(Severe acute
respiratory
syndrome-related
coronavirus) 		PF06460
(NSP13) 		3 ASP A  99
ASP A 114
ASP A 130
 SAH  A1293 (-2.7A)
SAH  A1293 (-3.7A)
SAH  A1293 (-3.7A)
 0.36A 1ej0A-2xyqA:
14.8		 1ej0A-2xyqA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yv2 SUCCINYL-COA
SYNTHETASE ALPHA
CHAIN

(Aeropyrum
pernix) 		PF00549
(Ligase_CoA)
PF02629
(CoA_binding) 		3 ASP A  86
ASP A  93
ASP A 110
 None
 0.68A 1ej0A-2yv2A:
7.1		 1ej0A-2yv2A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yxl 450AA LONG
HYPOTHETICAL FMU
PROTEIN

(Pyrococcus
horikoshii) 		PF01189
(Methyltr_RsmB-F)
PF17125
(Methyltr_RsmF_N) 		3 ASP A 291
ASP A 318
ASP A 337
 SFG  A5748 (-2.9A)
SFG  A5748 (-3.7A)
SFG  A5748 (-3.6A)
 0.63A 1ej0A-2yxlA:
12.1		 1ej0A-2yxlA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a0f XYLOGLUCANASE

(Geotrichum sp.
M128) 		no annotation 3 ASP A  76
ASP A 139
ASP A  81
 None
 0.72A 1ej0A-3a0fA:
undetectable		 1ej0A-3a0fA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b6v KINESIN-LIKE PROTEIN
KIF3C

(Homo sapiens) 		PF00225
(Kinesin) 		3 ASP A  65
ASP A  36
ASP A  72
 UNX  A1003 (-4.8A)
None
None
 0.62A 1ej0A-3b6vA:
undetectable		 1ej0A-3b6vA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bz5 INTERNALIN-J

(Listeria
monocytogenes) 		PF12799
(LRR_4) 		3 ASP A 404
ASP A 385
ASP A 447
 None
 0.69A 1ej0A-3bz5A:
undetectable		 1ej0A-3bz5A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c3y O-METHYLTRANSFERASE

(Mesembryanthemum
crystallinum) 		PF01596
(Methyltransf_3) 		3 ASP A 102
ASP A 130
ASP A 154
 SAH  A 464 (-2.8A)
SAH  A 464 (-4.1A)
CA  A 238 ( 2.2A)
 0.65A 1ej0A-3c3yA:
14.4		 1ej0A-3c3yA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c9f 5'-NUCLEOTIDASE

(Candida
albicans) 		PF00149
(Metallophos) 		3 ASP A 108
ASP A  72
ASP A 136
 None
 0.78A 1ej0A-3c9fA:
undetectable		 1ej0A-3c9fA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dli METHYLTRANSFERASE

(Archaeoglobus
fulgidus) 		PF13489
(Methyltransf_23) 		3 ASP A 311
ASP A 315
ASP A 330
 None
 0.74A 1ej0A-3dliA:
12.4		 1ej0A-3dliA:
22.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3dou RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J

(Thermoplasma
volcanium) 		PF01728
(FtsJ) 		3 ASP A  67
ASP A  83
ASP A 111
 SAM  A   1 (-2.7A)
SAM  A   1 (-3.6A)
SAM  A   1 (-3.7A)
 0.20A 1ej0A-3douA:
26.8		 1ej0A-3douA:
33.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ghg FIBRINOGEN GAMMA
CHAIN

(Homo sapiens) 		PF00147
(Fibrinogen_C)
PF08702
(Fib_alpha) 		3 ASP C 294
ASP C 298
ASP C 291
 ASP  C 294 ( 0.5A)
ASP  C 298 ( 0.6A)
ASP  C 291 ( 0.6A)
 0.74A 1ej0A-3ghgC:
undetectable		 1ej0A-3ghgC:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hm7 ALLANTOINASE

(Bacillus
halodurans) 		PF01979
(Amidohydro_1) 		3 ASP A 437
ASP A 405
ASP A 394
 None
 0.60A 1ej0A-3hm7A:
undetectable		 1ej0A-3hm7A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j4r CAMP-DEPENDENT
PROTEIN KINASE TYPE
II-ALPHA REGULATORY
SUBUNIT

(Mus musculus) 		PF00027
(cNMP_binding)
PF02197
(RIIa) 		3 ASP B 183
ASP B 199
ASP B 161
 None
 0.71A 1ej0A-3j4rB:
undetectable		 1ej0A-3j4rB:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j9d OUTER CAPSID PROTEIN
VP2

(Bluetongue
virus) 		PF00898
(Orbi_VP2) 		3 ASP A 415
ASP A 543
ASP A 571
 None
 0.78A 1ej0A-3j9dA:
undetectable		 1ej0A-3j9dA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l39 PUTATIVE PHOU-LIKE
PHOSPHATE REGULATORY
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF01865
(PhoU_div) 		3 ASP A  93
ASP A  61
ASP A  86
 None
 0.73A 1ej0A-3l39A:
undetectable		 1ej0A-3l39A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lpd ACIDIC EXTRACELLULAR
SUBTILISIN-LIKE
PROTEASE APRV2

(Dichelobacter
nodosus) 		PF00082
(Peptidase_S8) 		3 ASP A  79
ASP A  69
ASP A  41
 None
CA  A 342 ( 2.5A)
None
 0.79A 1ej0A-3lpdA:
undetectable		 1ej0A-3lpdA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lvv GLUTAMATE--CYSTEINE
LIGASE

(Saccharomyces
cerevisiae) 		PF03074
(GCS) 		3 ASP A 166
ASP A  59
ASP A 172
 PGE  A 698 (-4.3A)
None
None
 0.75A 1ej0A-3lvvA:
undetectable		 1ej0A-3lvvA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p4g ANTIFREEZE PROTEIN

(Marinomonas
primoryensis) 		no annotation 3 ASP A 177
ASP A 196
ASP A 139
 None
None
MG  A 324 ( 2.9A)
 0.57A 1ej0A-3p4gA:
undetectable		 1ej0A-3p4gA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1

(Bacillus
halodurans) 		PF00171
(Aldedh) 		3 ASP A 331
ASP A 334
ASP A 429
 None
 0.67A 1ej0A-3qanA:
3.7		 1ej0A-3qanA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r24 2'-O-METHYL
TRANSFERASE

(Severe acute
respiratory
syndrome-related
coronavirus) 		PF06460
(NSP13) 		3 ASP A  99
ASP A 114
ASP A 130
 SAM  A 302 (-2.6A)
SAM  A 302 (-3.4A)
SAM  A 302 (-3.6A)
 0.41A 1ej0A-3r24A:
14.8		 1ej0A-3r24A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3slg PBGP3 PROTEIN

(Burkholderia
pseudomallei) 		PF01370
(Epimerase) 		3 ASP A  35
ASP A  39
ASP A  56
 None
 0.77A 1ej0A-3slgA:
6.4		 1ej0A-3slgA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ssm METHYLTRANSFERASE

(Micromonospora
griseorubida) 		no annotation 3 ASP A 234
ASP A 252
ASP A 275
 SAH  A 601 (-2.8A)
SAH  A 601 (-3.6A)
MG  A 501 ( 2.8A)
 0.76A 1ej0A-3ssmA:
13.1		 1ej0A-3ssmA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tdu DCN1-LIKE PROTEIN 1

(Homo sapiens) 		PF03556
(Cullin_binding) 		3 ASP A  91
ASP A  96
ASP A  84
 None
 0.65A 1ej0A-3tduA:
undetectable		 1ej0A-3tduA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tos CALS11

(Micromonospora
echinospora) 		PF05711
(TylF) 		3 ASP A 107
ASP A 166
ASP A 189
 SAH  A 258 (-2.7A)
SAH  A 258 (-3.4A)
SAH  A 258 ( 3.6A)
 0.46A 1ej0A-3tosA:
10.7		 1ej0A-3tosA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aco CENTROMERE
DNA-BINDING PROTEIN
COMPLEX CBF3 SUBUNIT
A

(Saccharomyces
cerevisiae) 		PF16787
(NDC10_II) 		3 ASP A 312
ASP A 320
ASP A 456
 None
 0.74A 1ej0A-4acoA:
undetectable		 1ej0A-4acoA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dyk AMIDOHYDROLASE

(Pseudomonas
aeruginosa) 		PF01979
(Amidohydro_1) 		3 ASP A 401
ASP A 318
ASP A 378
 None
 0.78A 1ej0A-4dykA:
undetectable		 1ej0A-4dykA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ewt PEPTIDASE,
M20/M25/M40 FAMILY

(Staphylococcus
aureus) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		3 ASP A 296
ASP A 258
ASP A 334
 None
 0.78A 1ej0A-4ewtA:
undetectable		 1ej0A-4ewtA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fzv PUTATIVE
METHYLTRANSFERASE
NSUN4

(Homo sapiens) 		PF01189
(Methyltr_RsmB-F) 		3 ASP A 204
ASP A 237
ASP A 255
 SAM  A 401 (-2.9A)
SAM  A 401 (-3.5A)
SAM  A 401 (-3.7A)
 0.61A 1ej0A-4fzvA:
9.0		 1ej0A-4fzvA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gao DCN1-LIKE PROTEIN 2

(Homo sapiens) 		PF03556
(Cullin_binding) 		3 ASP A  91
ASP A  96
ASP A  84
 None
 0.59A 1ej0A-4gaoA:
undetectable		 1ej0A-4gaoA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gpg PROTEASE 1

(Achromobacter
lyticus) 		PF00089
(Trypsin) 		3 ASP A 259
ASP A  20
ASP A 135
 None
 0.77A 1ej0A-4gpgA:
undetectable		 1ej0A-4gpgA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hz4 GLUTATHIONE-S-TRANSF
ERASE

(Actinobacillus
pleuropneumoniae) 		PF00043
(GST_C)
PF02798
(GST_N) 		3 ASP A  60
ASP A  77
ASP A  62
 None
 0.75A 1ej0A-4hz4A:
undetectable		 1ej0A-4hz4A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ife GENE 2 PROTEIN

(Shigella virus
Sf6) 		PF04466
(Terminase_3)
PF17288
(Terminase_3C) 		3 ASP A 244
ASP A 251
ASP A 298
 None
 0.73A 1ej0A-4ifeA:
3.7		 1ej0A-4ifeA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)

(Parkia
biglobosa) 		PF01419
(Jacalin) 		3 ASP A 431
ASP A 311
ASP A 385
 MMA  A 502 (-3.1A)
None
None
 0.68A 1ej0A-4mq0A:
undetectable		 1ej0A-4mq0A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rl1 TYPE I POLYKETIDE
SYNTHASE AVES 1

(Streptomyces
avermitilis) 		PF00698
(Acyl_transf_1) 		3 ASP A  89
ASP A  86
ASP A  69
 None
 0.77A 1ej0A-4rl1A:
undetectable		 1ej0A-4rl1A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wiw GLYCOSIDE HYDROLASE
FAMILY 18

(Desulfitobacterium
hafniense) 		PF00704
(Glyco_hydro_18) 		3 ASP A 464
ASP A 478
ASP A 467
 None
 0.69A 1ej0A-4wiwA:
undetectable		 1ej0A-4wiwA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xmv AMINOPEPTIDASE N

(Escherichia
coli) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		3 ASP A 427
ASP A 432
ASP A 420
 None
 0.62A 1ej0A-4xmvA:
undetectable		 1ej0A-4xmvA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yv2 SPERMIDINE SYNTHASE,
PUTATIVE

(Trypanosoma
cruzi) 		PF01564
(Spermine_synth)
PF17284
(Spermine_synt_N) 		3 ASP A 118
ASP A 149
ASP A 168
 S4M  A 301 (-3.0A)
S4M  A 301 (-3.9A)
S4M  A 301 (-3.1A)
 0.79A 1ej0A-4yv2A:
11.4		 1ej0A-4yv2A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zke SUPERKILLER PROTEIN
7

(Saccharomyces
cerevisiae) 		PF00009
(GTP_EFTU) 		3 ASP A 669
ASP A 695
ASP A 666
 ASP  A 669 ( 0.5A)
ASP  A 695 ( 0.6A)
ASP  A 666 ( 0.6A)
 0.67A 1ej0A-4zkeA:
undetectable		 1ej0A-4zkeA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zte CADHERIN-1

(Homo sapiens) 		PF00028
(Cadherin) 		3 ASP A 100
ASP A  67
ASP A 138
 CA  A 402 (-3.0A)
CA  A 403 (-3.0A)
None
 0.66A 1ej0A-4zteA:
undetectable		 1ej0A-4zteA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a4j FORMATE--TETRAHYDROF
OLATE LIGASE

(Tepidanaerobacter
acetatoxydans) 		PF01268
(FTHFS) 		3 ASP A  43
ASP A 252
ASP A  30
 EDO  A1562 (-2.9A)
None
None
 0.70A 1ej0A-5a4jA:
2.2		 1ej0A-5a4jA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a5g FORMATE--TETRAHYDROF
OLATE LIGASE

(Tepidanaerobacter
acetatoxydans) 		PF01268
(FTHFS) 		3 ASP A  43
ASP A 251
ASP A  30
 None
 0.69A 1ej0A-5a5gA:
undetectable		 1ej0A-5a5gA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5by3 BTGH115A

(Bacteroides
thetaiotaomicron) 		PF15979
(Glyco_hydro_115) 		3 ASP A 585
ASP A 590
ASP A 582
 None
 0.62A 1ej0A-5by3A:
undetectable		 1ej0A-5by3A:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c2v HYDRAZINE SYNTHASE
BETA SUBUNIT

(Candidatus
Kuenenia
stuttgartiensis) 		PF02239
(Cytochrom_D1) 		3 ASP B 337
ASP B 281
ASP B 333
 None
 0.74A 1ej0A-5c2vB:
undetectable		 1ej0A-5c2vB:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5co1 PROTOCADHERIN-19
ISOFORM 1

(Danio rerio) 		PF00028
(Cadherin) 		3 ASP A 236
ASP A 216
ASP A 269
 CA  A1004 (-3.1A)
None
None
 0.71A 1ej0A-5co1A:
undetectable		 1ej0A-5co1A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dll AMINOPEPTIDASE N

(Francisella
tularensis) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		3 ASP A 436
ASP A 441
ASP A 429
 None
CL  A 915 ( 4.7A)
None
 0.73A 1ej0A-5dllA:
undetectable		 1ej0A-5dllA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ek5 IRMA

(Escherichia
coli) 		no annotation 3 ASP A  78
ASP A  17
ASP A  33
 None
 0.51A 1ej0A-5ek5A:
undetectable		 1ej0A-5ek5A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f7c ALPHA-GLUCOSIDASE

(Bacteroides
thetaiotaomicron) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		3 ASP A  55
ASP A 177
ASP A  16
 None
 0.78A 1ej0A-5f7cA:
undetectable		 1ej0A-5f7cA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE

(Schistosoma
mansoni) 		PF01048
(PNP_UDP_1) 		3 ASP A  95
ASP A 202
ASP A 164
 None
 0.65A 1ej0A-5f7oA:
undetectable		 1ej0A-5f7oA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jlc LANOSTEROL 14-ALPHA
DEMETHYLASE

([Candida]
glabrata) 		PF00067
(p450) 		3 ASP A 391
ASP A  55
ASP A 404
 None
 0.56A 1ej0A-5jlcA:
undetectable		 1ej0A-5jlcA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jp9 CMP
5-HYDROXYMETHYLASE

(Streptomyces
rimofaciens) 		PF00303
(Thymidylat_synt) 		3 ASP A 305
ASP A 302
ASP A 274
 None
 0.74A 1ej0A-5jp9A:
undetectable		 1ej0A-5jp9A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kgn 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Caenorhabditis
elegans) 		PF01676
(Metalloenzyme)
PF06415
(iPGM_N) 		3 ASP A 286
ASP A 282
ASP A 217
 GOL  A 602 ( 4.8A)
None
None
 0.74A 1ej0A-5kgnA:
2.4		 1ej0A-5kgnA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lkd GLUTATHIONE
S-TRANSFERASE
OMEGA-LIKE 2

(Saccharomyces
cerevisiae) 		PF13409
(GST_N_2)
PF13410
(GST_C_2) 		3 ASP A 129
ASP A 122
ASP A 340
 None
 0.59A 1ej0A-5lkdA:
undetectable		 1ej0A-5lkdA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5log PUTATIVE
O-METHYLTRANSFERASE

(Myxococcus
xanthus) 		PF01596
(Methyltransf_3) 		3 ASP A  91
ASP A 119
ASP A 142
 SAH  A1001 (-2.8A)
SAH  A1001 (-3.8A)
MG  A1002 (-2.5A)
 0.67A 1ej0A-5logA:
14.1		 1ej0A-5logA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m58 C-METHYLTRANSFERASE
COUO

(Streptomyces
rishiriensis) 		PF13649
(Methyltransf_25) 		3 ASP A  70
ASP A  74
ASP A  96
 SAH  A 301 (-2.8A)
None
SAH  A 301 (-3.5A)
 0.73A 1ej0A-5m58A:
12.1		 1ej0A-5m58A:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m6u PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka)
PF00792
(PI3K_C2)
PF00794
(PI3K_rbd)
PF02192
(PI3K_p85B) 		3 ASP A 383
ASP A 378
ASP A 560
 None
 0.78A 1ej0A-5m6uA:
undetectable		 1ej0A-5m6uA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mgz 8-DEMETHYLNOVOBIOCIC
ACID
C(8)-METHYLTRANSFERA
SE

(Streptomyces
niveus) 		PF13649
(Methyltransf_25) 		3 ASP A  70
ASP A  74
ASP A  96
 SAH  A 301 (-2.8A)
None
SAH  A 301 (-3.5A)
 0.71A 1ej0A-5mgzA:
10.4		 1ej0A-5mgzA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v88 LYSOZYME,DCN1-LIKE
PROTEIN 1

(Homo sapiens;
Escherichia
virus T4) 		PF00959
(Phage_lysozyme)
PF03556
(Cullin_binding) 		3 ASP A1091
ASP A1096
ASP A1084
 None
 0.60A 1ej0A-5v88A:
undetectable		 1ej0A-5v88A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5whs CATALASE-PEROXIDASE

(Neurospora
crassa) 		no annotation 3 ASP A 664
ASP A 657
ASP A 683
 None
 0.78A 1ej0A-5whsA:
undetectable		 1ej0A-5whsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wwt PUTATIVE
METHYLTRANSFERASE
NSUN6

(Homo sapiens) 		PF01189
(Methyltr_RsmB-F) 		3 ASP A 266
ASP A 293
ASP A 323
 None
None
C  C  72 ( 2.8A)
 0.63A 1ej0A-5wwtA:
10.6		 1ej0A-5wwtA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x3e KINESIN-LIKE PROTEIN

(Caenorhabditis
elegans) 		PF00225
(Kinesin) 		3 ASP A 223
ASP A 249
ASP A 227
 None
None
SO4  A 519 (-4.4A)
 0.76A 1ej0A-5x3eA:
undetectable		 1ej0A-5x3eA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x8h SHORT-CHAIN
DEHYDROGENASE
REDUCTASE

(Chryseobacterium
sp. CA49) 		no annotation 3 ASP A  37
ASP A  41
ASP A  63
 None
 0.72A 1ej0A-5x8hA:
9.9		 1ej0A-5x8hA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xne -

(-) 		no annotation 3 ASP B  33
ASP B 239
ASP B 232
 None
 0.71A 1ej0A-5xneB:
undetectable		 1ej0A-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ygu DIAMINOPIMELATE
EPIMERASE

(Escherichia
coli) 		no annotation 3 ASP A  57
ASP A  53
ASP A  94
 None
 0.65A 1ej0A-5yguA:
undetectable		 1ej0A-5yguA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zqz TRIFUNCTIONAL ENZYME
SUBUNIT ALPHA,
MITOCHONDRIAL

(Homo sapiens) 		no annotation 3 ASP A 567
ASP A 572
ASP A 653
 None
 0.62A 1ej0A-5zqzA:
5.7		 1ej0A-5zqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fah CAFFEYL-COA
REDUCTASE-ETF
COMPLEX SUBUNIT CARE

(Acetobacterium
woodii) 		no annotation 3 ASP A 277
ASP A 355
ASP A 275
 None
 0.68A 1ej0A-6fahA:
2.1		 1ej0A-6fahA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gsa -

(-) 		no annotation 3 ASP E 312
ASP E 320
ASP E 456
 None
 0.74A 1ej0A-6gsaE:
undetectable		 1ej0A-6gsaE:
undetectable