SIMILAR PATTERNS OF AMINO ACIDS FOR 1EIZ_A_SAMA301_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1amy | 1,4-ALPHA-D-GLUCANGLUCANOHYDROLASE (Hordeum vulgare) |
PF00128(Alpha-amylase)PF07821(Alpha-amyl_C2) | 3 | ASP A 396ASP A 302ASP A 360 | None | 0.66A | 1eizA-1amyA:undetectable | 1eizA-1amyA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c30 | CARBAMOYL PHOSPHATESYNTHETASE: LARGESUBUNIT (Escherichiacoli) |
PF02142(MGS)PF02786(CPSase_L_D2)PF02787(CPSase_L_D3) | 3 | ASP A 128ASP A 121ASP A 133 | NoneNone K A4019 ( 4.6A) | 0.74A | 1eizA-1c30A:4.9 | 1eizA-1c30A:10.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ckm | MRNA CAPPING ENZYME (ParameciumbursariaChlorella virus1) |
PF01331(mRNA_cap_enzyme)PF03919(mRNA_cap_C) | 3 | ASP A 45ASP A 49ASP A 38 | None | 0.60A | 1eizA-1ckmA:undetectable | 1eizA-1ckmA:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d0n | HORSE PLASMAGELSOLIN (Equus caballus) |
PF00626(Gelsolin) | 3 | ASP A 670ASP A 687ASP A 665 | None | 0.71A | 1eizA-1d0nA:undetectable | 1eizA-1d0nA:14.68 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1eiz | FTSJ (Escherichiacoli) |
PF01728(FtsJ) | 3 | ASP A 83ASP A 99ASP A 124 | SAM A 301 (-2.8A)SAM A 301 (-3.5A)SAM A 301 (-3.6A) | 0.01A | 1eizA-1eizA:38.6 | 1eizA-1eizA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ezw | COENZYMEF420-DEPENDENTN5,N10-METHYLENETETRAHYDROMETHANOPTERINREDUCTASE (Methanopyruskandleri) |
PF00296(Bac_luciferase) | 3 | ASP A 303ASP A 239ASP A 309 | None | 0.69A | 1eizA-1ezwA:undetectable | 1eizA-1ezwA:19.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ioo | SF11-RNASE (Nicotiana alata) |
PF00445(Ribonuclease_T2) | 3 | ASP A 113ASP A 116ASP A 62 | NAG A 198 ( 3.5A)NAG A 197 (-3.7A)XYP A 200 ( 4.6A) | 0.72A | 1eizA-1iooA:undetectable | 1eizA-1iooA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jxi | PHOSPHOMETHYLPYRIMIDINE KINASE (Salmonellaenterica) |
PF08543(Phos_pyr_kin) | 3 | ASP A 58ASP A 65ASP A 85 | None | 0.74A | 1eizA-1jxiA:3.5 | 1eizA-1jxiA:25.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k9x | M32 CARBOXYPEPTIDASE (Pyrococcusfuriosus) |
PF02074(Peptidase_M32) | 3 | ASP A 171ASP A 161ASP A 484 | None | 0.77A | 1eizA-1k9xA:undetectable | 1eizA-1k9xA:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lss | TRK SYSTEM POTASSIUMUPTAKE PROTEIN TRKAHOMOLOG (Methanocaldococcusjannaschii) |
PF02254(TrkA_N) | 3 | ASP A 30ASP A 34ASP A 51 | NAD A1001 (-2.9A)NoneNAD A1001 (-3.3A) | 0.64A | 1eizA-1lssA:8.2 | 1eizA-1lssA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mi8 | DNAB INTEIN (Synechocystissp. PCC 6803) |
PF14890(Intein_splicing) | 3 | ASP A 21ASP A 24ASP A 5 | None | 0.74A | 1eizA-1mi8A:undetectable | 1eizA-1mi8A:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ne2 | HYPOTHETICAL PROTEINTA1320 (Thermoplasmaacidophilum) |
PF06325(PrmA) | 3 | ASP A 78ASP A 82ASP A 100 | None | 0.67A | 1eizA-1ne2A:13.1 | 1eizA-1ne2A:23.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nw5 | MODIFICATIONMETHYLASE RSRI (Rhodobactersphaeroides) |
PF01555(N6_N4_Mtase) | 3 | ASP A 271ASP A 46ASP A 65 | SAM A 401 (-2.9A)SAM A 401 (-3.6A)SAM A 401 (-3.3A) | 0.54A | 1eizA-1nw5A:2.8 | 1eizA-1nw5A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pp0 | VOLVATOXIN A2 (Volvariellavolvacea) |
PF01338(Bac_thur_toxin) | 3 | ASP A 64ASP A 61ASP A 88 | None | 0.75A | 1eizA-1pp0A:undetectable | 1eizA-1pp0A:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qb4 | PHOSPHOENOLPYRUVATECARBOXYLASE (Escherichiacoli) |
PF00311(PEPcase) | 3 | ASP A 510ASP A 543ASP A 482 | None MN A 885 (-3.0A)None | 0.79A | 1eizA-1qb4A:undetectable | 1eizA-1qb4A:11.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sqg | SUN PROTEIN (Escherichiacoli) |
PF01029(NusB)PF01189(Methyltr_RsmB-F) | 3 | ASP A 277ASP A 303ASP A 322 | None | 0.60A | 1eizA-1sqgA:11.4 | 1eizA-1sqgA:19.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1taq | TAQ DNA POLYMERASE (Thermusaquaticus) |
PF00476(DNA_pol_A)PF01367(5_3_exonuc)PF02739(5_3_exonuc_N)PF09281(Taq-exonuc) | 3 | ASP A 120ASP A 251ASP A 144 | None | 0.66A | 1eizA-1taqA:undetectable | 1eizA-1taqA:12.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ve3 | HYPOTHETICAL PROTEINPH0226 (Pyrococcushorikoshii) |
PF13649(Methyltransf_25) | 3 | ASP A 67ASP A 71ASP A 93 | SAM A 302 (-2.8A)NoneSAM A 302 (-3.4A) | 0.67A | 1eizA-1ve3A:11.8 | 1eizA-1ve3A:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vl5 | UNKNOWN CONSERVEDPROTEIN BH2331 (Bacillushalodurans) |
PF08241(Methyltransf_11) | 3 | ASP A 71ASP A 75ASP A 98 | None | 0.76A | 1eizA-1vl5A:12.8 | 1eizA-1vl5A:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xkh | FERRIPYOVERDINERECEPTOR (Pseudomonasaeruginosa) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 3 | ASP A 509ASP A 323ASP A 501 | None | 0.66A | 1eizA-1xkhA:undetectable | 1eizA-1xkhA:15.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yo6 | PUTATIVE CARBONYLREDUCTASE SNIFFER (Caenorhabditiselegans) |
PF00106(adh_short) | 3 | ASP A 192ASP A 138ASP A 189 | None | 0.59A | 1eizA-1yo6A:9.7 | 1eizA-1yo6A:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yr2 | PROLYLOLIGOPEPTIDASE (Novosphingobiumcapsulatum) |
PF00326(Peptidase_S9)PF02897(Peptidase_S9_N) | 3 | ASP A 172ASP A 220ASP A 278 | None | 0.68A | 1eizA-1yr2A:2.6 | 1eizA-1yr2A:13.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b9e | NOL1/NOP2/SUN DOMAINFAMILY, MEMBER 5ISOFORM 2 (Homo sapiens) |
PF01189(Methyltr_RsmB-F) | 3 | ASP A 258ASP A 285ASP A 305 | SAM A1201 (-2.6A)SAM A1201 (-3.6A)SAM A1201 (-3.7A) | 0.59A | 1eizA-2b9eA:11.9 | 1eizA-2b9eA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dul | N(2),N(2)-DIMETHYLGUANOSINE TRNAMETHYLTRANSFERASE (Pyrococcushorikoshii) |
PF02005(TRM) | 3 | ASP A 78ASP A 82ASP A 120 | None | 0.68A | 1eizA-2dulA:9.6 | 1eizA-2dulA:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iny | HEXON PROTEIN (Fowlaviadenovirus A) |
PF01065(Adeno_hexon)PF03678(Adeno_hexon_C) | 3 | ASP A 499ASP A 898ASP A 770 | None | 0.75A | 1eizA-2inyA:undetectable | 1eizA-2inyA:10.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kma | TALIN 1 (Mus musculus) |
PF09379(FERM_N)PF16511(FERM_f0) | 3 | ASP A 77ASP A 69ASP A 53 | None | 0.73A | 1eizA-2kmaA:undetectable | 1eizA-2kmaA:20.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2nyu | PUTATIVE RIBOSOMALRNAMETHYLTRANSFERASE 2 (Homo sapiens) |
PF01728(FtsJ) | 3 | ASP A 62ASP A 79ASP A 104 | SAM A 201 (-2.8A)SAM A 201 (-3.3A)SAM A 201 (-3.7A) | 0.38A | 1eizA-2nyuA:26.6 | 1eizA-2nyuA:36.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oka | HYPOTHETICAL PROTEIN (Pseudomonasaeruginosa) |
PF10262(Rdx) | 3 | ASP A 83ASP A 35ASP A 87 | None | 0.72A | 1eizA-2okaA:undetectable | 1eizA-2okaA:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pg8 | DPGC (Streptomycestoyocaensis) |
PF00378(ECH_1) | 3 | ASP A 195ASP A 202ASP A 249 | None | 0.64A | 1eizA-2pg8A:undetectable | 1eizA-2pg8A:17.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qvs | CAMP-DEPENDENTPROTEIN KINASE TYPEII-ALPHA REGULATORYSUBUNIT (Mus musculus) |
PF00027(cNMP_binding) | 3 | ASP B 181ASP B 197ASP B 159 | ASP B 181 ( 0.5A)ASP B 197 ( 0.6A)ASP B 159 ( 0.5A) | 0.71A | 1eizA-2qvsB:undetectable | 1eizA-2qvsB:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vrn | PROTEASE I (Deinococcusradiodurans) |
PF01965(DJ-1_PfpI) | 3 | ASP A 77ASP A 184ASP A 75 | None | 0.75A | 1eizA-2vrnA:3.1 | 1eizA-2vrnA:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xmr | PROTEIN NDRG2 (Homo sapiens) |
PF03096(Ndr) | 3 | ASP A 158ASP A 228ASP A 255 | None | 0.63A | 1eizA-2xmrA:undetectable | 1eizA-2xmrA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xyq | PUTATIVE 2'-O-METHYLTRANSFERASE (Severe acuterespiratorysyndrome-relatedcoronavirus) |
PF06460(NSP13) | 3 | ASP A 99ASP A 114ASP A 130 | SAH A1293 (-2.7A)SAH A1293 (-3.7A)SAH A1293 (-3.7A) | 0.32A | 1eizA-2xyqA:14.8 | 1eizA-2xyqA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yv2 | SUCCINYL-COASYNTHETASE ALPHACHAIN (Aeropyrumpernix) |
PF00549(Ligase_CoA)PF02629(CoA_binding) | 3 | ASP A 86ASP A 93ASP A 110 | None | 0.66A | 1eizA-2yv2A:7.2 | 1eizA-2yv2A:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yxl | 450AA LONGHYPOTHETICAL FMUPROTEIN (Pyrococcushorikoshii) |
PF01189(Methyltr_RsmB-F)PF17125(Methyltr_RsmF_N) | 3 | ASP A 291ASP A 318ASP A 337 | SFG A5748 (-2.9A)SFG A5748 (-3.7A)SFG A5748 (-3.6A) | 0.58A | 1eizA-2yxlA:12.0 | 1eizA-2yxlA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a0f | XYLOGLUCANASE (Geotrichum sp.M128) |
no annotation | 3 | ASP A 76ASP A 139ASP A 81 | None | 0.71A | 1eizA-3a0fA:undetectable | 1eizA-3a0fA:12.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3anx | SPERMIDINE SYNTHASE (Thermusthermophilus) |
PF01564(Spermine_synth)PF17284(Spermine_synt_N) | 3 | ASP A 108ASP A 140ASP A 158 | MTA A 315 (-3.3A)MTA A 315 (-3.9A)MTA A 315 (-4.9A) | 0.77A | 1eizA-3anxA:11.2 | 1eizA-3anxA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b6v | KINESIN-LIKE PROTEINKIF3C (Homo sapiens) |
PF00225(Kinesin) | 3 | ASP A 65ASP A 36ASP A 72 | UNX A1003 (-4.8A)NoneNone | 0.60A | 1eizA-3b6vA:undetectable | 1eizA-3b6vA:17.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bz5 | INTERNALIN-J (Listeriamonocytogenes) |
PF12799(LRR_4) | 3 | ASP A 404ASP A 385ASP A 447 | None | 0.73A | 1eizA-3bz5A:undetectable | 1eizA-3bz5A:17.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c3y | O-METHYLTRANSFERASE (Mesembryanthemumcrystallinum) |
PF01596(Methyltransf_3) | 3 | ASP A 102ASP A 130ASP A 154 | SAH A 464 (-2.8A)SAH A 464 (-4.1A) CA A 238 ( 2.2A) | 0.61A | 1eizA-3c3yA:14.4 | 1eizA-3c3yA:24.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c9f | 5'-NUCLEOTIDASE (Candidaalbicans) |
PF00149(Metallophos) | 3 | ASP A 108ASP A 72ASP A 136 | None | 0.80A | 1eizA-3c9fA:undetectable | 1eizA-3c9fA:17.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dli | METHYLTRANSFERASE (Archaeoglobusfulgidus) |
PF13489(Methyltransf_23) | 3 | ASP A 311ASP A 315ASP A 330 | None | 0.73A | 1eizA-3dliA:12.6 | 1eizA-3dliA:22.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3dou | RIBOSOMAL RNA LARGESUBUNITMETHYLTRANSFERASE J (Thermoplasmavolcanium) |
PF01728(FtsJ) | 3 | ASP A 67ASP A 83ASP A 111 | SAM A 1 (-2.7A)SAM A 1 (-3.6A)SAM A 1 (-3.7A) | 0.15A | 1eizA-3douA:26.9 | 1eizA-3douA:33.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fok | UNCHARACTERIZEDPROTEIN CGL0159 (Corynebacteriumglutamicum) |
no annotation | 3 | ASP A 298ASP A 41ASP A 289 | None | 0.65A | 1eizA-3fokA:undetectable | 1eizA-3fokA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ghg | FIBRINOGEN GAMMACHAIN (Homo sapiens) |
PF00147(Fibrinogen_C)PF08702(Fib_alpha) | 3 | ASP C 294ASP C 298ASP C 291 | ASP C 294 ( 0.5A)ASP C 298 ( 0.6A)ASP C 291 ( 0.6A) | 0.79A | 1eizA-3ghgC:undetectable | 1eizA-3ghgC:15.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hm7 | ALLANTOINASE (Bacillushalodurans) |
PF01979(Amidohydro_1) | 3 | ASP A 437ASP A 405ASP A 394 | None | 0.62A | 1eizA-3hm7A:2.1 | 1eizA-3hm7A:18.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j4r | CAMP-DEPENDENTPROTEIN KINASE TYPEII-ALPHA REGULATORYSUBUNIT (Mus musculus) |
PF00027(cNMP_binding)PF02197(RIIa) | 3 | ASP B 183ASP B 199ASP B 161 | None | 0.72A | 1eizA-3j4rB:undetectable | 1eizA-3j4rB:17.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j9d | OUTER CAPSID PROTEINVP2 (Bluetonguevirus) |
PF00898(Orbi_VP2) | 3 | ASP A 415ASP A 543ASP A 571 | None | 0.75A | 1eizA-3j9dA:undetectable | 1eizA-3j9dA:11.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k70 | EXODEOXYRIBONUCLEASEV BETA CHAIN (Escherichiacoli) |
PF00580(UvrD-helicase)PF12705(PDDEXK_1)PF13361(UvrD_C) | 3 | ASP B 388ASP B 426ASP B 414 | None | 0.78A | 1eizA-3k70B:2.8 | 1eizA-3k70B:9.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l39 | PUTATIVE PHOU-LIKEPHOSPHATE REGULATORYPROTEIN (Bacteroidesthetaiotaomicron) |
PF01865(PhoU_div) | 3 | ASP A 93ASP A 61ASP A 86 | None | 0.74A | 1eizA-3l39A:undetectable | 1eizA-3l39A:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lpd | ACIDIC EXTRACELLULARSUBTILISIN-LIKEPROTEASE APRV2 (Dichelobacternodosus) |
PF00082(Peptidase_S8) | 3 | ASP A 79ASP A 69ASP A 41 | None CA A 342 ( 2.5A)None | 0.79A | 1eizA-3lpdA:undetectable | 1eizA-3lpdA:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lvv | GLUTAMATE--CYSTEINELIGASE (Saccharomycescerevisiae) |
PF03074(GCS) | 3 | ASP A 166ASP A 59ASP A 172 | PGE A 698 (-4.3A)NoneNone | 0.69A | 1eizA-3lvvA:undetectable | 1eizA-3lvvA:13.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ow2 | 50S RIBOSOMALPROTEIN L15P (Haloarculamarismortui) |
PF00828(Ribosomal_L27A) | 3 | ASP K 123ASP K 104ASP K 144 | None | 0.78A | 1eizA-3ow2K:undetectable | 1eizA-3ow2K:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p4g | ANTIFREEZE PROTEIN (Marinomonasprimoryensis) |
no annotation | 3 | ASP A 177ASP A 196ASP A 139 | NoneNone MG A 324 ( 2.9A) | 0.59A | 1eizA-3p4gA:undetectable | 1eizA-3p4gA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qan | 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE1 (Bacillushalodurans) |
PF00171(Aldedh) | 3 | ASP A 331ASP A 334ASP A 429 | None | 0.66A | 1eizA-3qanA:undetectable | 1eizA-3qanA:15.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r24 | 2'-O-METHYLTRANSFERASE (Severe acuterespiratorysyndrome-relatedcoronavirus) |
PF06460(NSP13) | 3 | ASP A 99ASP A 114ASP A 130 | SAM A 302 (-2.6A)SAM A 302 (-3.4A)SAM A 302 (-3.6A) | 0.37A | 1eizA-3r24A:14.9 | 1eizA-3r24A:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ssm | METHYLTRANSFERASE (Micromonosporagriseorubida) |
no annotation | 3 | ASP A 234ASP A 252ASP A 275 | SAH A 601 (-2.8A)SAH A 601 (-3.6A) MG A 501 ( 2.8A) | 0.71A | 1eizA-3ssmA:13.0 | 1eizA-3ssmA:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tdu | DCN1-LIKE PROTEIN 1 (Homo sapiens) |
PF03556(Cullin_binding) | 3 | ASP A 91ASP A 96ASP A 84 | None | 0.67A | 1eizA-3tduA:undetectable | 1eizA-3tduA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tos | CALS11 (Micromonosporaechinospora) |
PF05711(TylF) | 3 | ASP A 107ASP A 166ASP A 189 | SAH A 258 (-2.7A)SAH A 258 (-3.4A)SAH A 258 ( 3.6A) | 0.43A | 1eizA-3tosA:10.4 | 1eizA-3tosA:24.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ulp | SINGLE-STRANDBINDING PROTEIN (Plasmodiumfalciparum) |
PF00436(SSB) | 3 | ASP A 138ASP A 189ASP A 143 | None | 0.67A | 1eizA-3ulpA:undetectable | 1eizA-3ulpA:18.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aco | CENTROMEREDNA-BINDING PROTEINCOMPLEX CBF3 SUBUNITA (Saccharomycescerevisiae) |
PF16787(NDC10_II) | 3 | ASP A 312ASP A 320ASP A 456 | None | 0.76A | 1eizA-4acoA:undetectable | 1eizA-4acoA:10.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dyk | AMIDOHYDROLASE (Pseudomonasaeruginosa) |
PF01979(Amidohydro_1) | 3 | ASP A 401ASP A 318ASP A 378 | None | 0.78A | 1eizA-4dykA:undetectable | 1eizA-4dykA:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ewt | PEPTIDASE,M20/M25/M40 FAMILY (Staphylococcusaureus) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 3 | ASP A 296ASP A 258ASP A 334 | None | 0.78A | 1eizA-4ewtA:undetectable | 1eizA-4ewtA:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fzv | PUTATIVEMETHYLTRANSFERASENSUN4 (Homo sapiens) |
PF01189(Methyltr_RsmB-F) | 3 | ASP A 204ASP A 237ASP A 255 | SAM A 401 (-2.9A)SAM A 401 (-3.5A)SAM A 401 (-3.7A) | 0.57A | 1eizA-4fzvA:9.1 | 1eizA-4fzvA:18.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gao | DCN1-LIKE PROTEIN 2 (Homo sapiens) |
PF03556(Cullin_binding) | 3 | ASP A 91ASP A 96ASP A 84 | None | 0.62A | 1eizA-4gaoA:undetectable | 1eizA-4gaoA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gpg | PROTEASE 1 (Achromobacterlyticus) |
PF00089(Trypsin) | 3 | ASP A 259ASP A 20ASP A 135 | None | 0.73A | 1eizA-4gpgA:undetectable | 1eizA-4gpgA:17.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hz4 | GLUTATHIONE-S-TRANSFERASE (Actinobacilluspleuropneumoniae) |
PF00043(GST_C)PF02798(GST_N) | 3 | ASP A 60ASP A 77ASP A 62 | None | 0.76A | 1eizA-4hz4A:undetectable | 1eizA-4hz4A:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ife | GENE 2 PROTEIN (Shigella virusSf6) |
PF04466(Terminase_3)PF17288(Terminase_3C) | 3 | ASP A 244ASP A 251ASP A 298 | None | 0.73A | 1eizA-4ifeA:4.3 | 1eizA-4ifeA:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mq0 | PARKIA BIGLOBOSALECTIN (PBL) (Parkiabiglobosa) |
PF01419(Jacalin) | 3 | ASP A 431ASP A 311ASP A 385 | MMA A 502 (-3.1A)NoneNone | 0.69A | 1eizA-4mq0A:undetectable | 1eizA-4mq0A:17.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nsy | LYSYL ENDOPEPTIDASE (Lysobacterenzymogenes) |
PF13365(Trypsin_2) | 3 | ASP A 259ASP A 20ASP A 135 | None | 0.79A | 1eizA-4nsyA:undetectable | 1eizA-4nsyA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rl1 | TYPE I POLYKETIDESYNTHASE AVES 1 (Streptomycesavermitilis) |
PF00698(Acyl_transf_1) | 3 | ASP A 89ASP A 86ASP A 69 | None | 0.78A | 1eizA-4rl1A:undetectable | 1eizA-4rl1A:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v1r | ALPHA-1,6-MANNANASE (Bacteroidesthetaiotaomicron) |
PF03663(Glyco_hydro_76) | 3 | ASP A 328ASP A 330ASP A 321 | None | 0.75A | 1eizA-4v1rA:undetectable | 1eizA-4v1rA:17.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xmv | AMINOPEPTIDASE N (Escherichiacoli) |
PF01433(Peptidase_M1)PF11940(DUF3458)PF17432(DUF3458_C) | 3 | ASP A 427ASP A 432ASP A 420 | None | 0.61A | 1eizA-4xmvA:undetectable | 1eizA-4xmvA:12.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zke | SUPERKILLER PROTEIN7 (Saccharomycescerevisiae) |
PF00009(GTP_EFTU) | 3 | ASP A 669ASP A 695ASP A 666 | ASP A 669 ( 0.5A)ASP A 695 ( 0.6A)ASP A 666 ( 0.6A) | 0.64A | 1eizA-4zkeA:3.3 | 1eizA-4zkeA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zte | CADHERIN-1 (Homo sapiens) |
PF00028(Cadherin) | 3 | ASP A 100ASP A 67ASP A 138 | CA A 402 (-3.0A) CA A 403 (-3.0A)None | 0.69A | 1eizA-4zteA:undetectable | 1eizA-4zteA:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a4j | FORMATE--TETRAHYDROFOLATE LIGASE (Tepidanaerobacteracetatoxydans) |
PF01268(FTHFS) | 3 | ASP A 43ASP A 252ASP A 30 | EDO A1562 (-2.9A)NoneNone | 0.71A | 1eizA-5a4jA:2.3 | 1eizA-5a4jA:17.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a5g | FORMATE--TETRAHYDROFOLATE LIGASE (Tepidanaerobacteracetatoxydans) |
PF01268(FTHFS) | 3 | ASP A 43ASP A 251ASP A 30 | None | 0.69A | 1eizA-5a5gA:undetectable | 1eizA-5a5gA:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5by3 | BTGH115A (Bacteroidesthetaiotaomicron) |
PF15979(Glyco_hydro_115) | 3 | ASP A 585ASP A 590ASP A 582 | None | 0.63A | 1eizA-5by3A:2.3 | 1eizA-5by3A:13.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c2v | HYDRAZINE SYNTHASEBETA SUBUNIT (CandidatusKueneniastuttgartiensis) |
PF02239(Cytochrom_D1) | 3 | ASP B 337ASP B 281ASP B 333 | None | 0.78A | 1eizA-5c2vB:undetectable | 1eizA-5c2vB:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5co1 | PROTOCADHERIN-19ISOFORM 1 (Danio rerio) |
PF00028(Cadherin) | 3 | ASP A 236ASP A 216ASP A 269 | CA A1004 (-3.1A)NoneNone | 0.76A | 1eizA-5co1A:undetectable | 1eizA-5co1A:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dll | AMINOPEPTIDASE N (Francisellatularensis) |
PF01433(Peptidase_M1)PF11940(DUF3458)PF17432(DUF3458_C) | 3 | ASP A 436ASP A 441ASP A 429 | None CL A 915 ( 4.7A)None | 0.72A | 1eizA-5dllA:undetectable | 1eizA-5dllA:10.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ek5 | IRMA (Escherichiacoli) |
no annotation | 3 | ASP A 78ASP A 17ASP A 33 | None | 0.52A | 1eizA-5ek5A:undetectable | 1eizA-5ek5A:17.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f7c | ALPHA-GLUCOSIDASE (Bacteroidesthetaiotaomicron) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2) | 3 | ASP A 55ASP A 177ASP A 16 | None | 0.79A | 1eizA-5f7cA:undetectable | 1eizA-5f7cA:12.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f7o | METHYLTHIOADENOSINEPHOSPHORYLASE (Schistosomamansoni) |
PF01048(PNP_UDP_1) | 3 | ASP A 95ASP A 202ASP A 164 | None | 0.66A | 1eizA-5f7oA:undetectable | 1eizA-5f7oA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jlc | LANOSTEROL 14-ALPHADEMETHYLASE ([Candida]glabrata) |
PF00067(p450) | 3 | ASP A 391ASP A 55ASP A 404 | None | 0.56A | 1eizA-5jlcA:undetectable | 1eizA-5jlcA:16.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jp9 | CMP5-HYDROXYMETHYLASE (Streptomycesrimofaciens) |
PF00303(Thymidylat_synt) | 3 | ASP A 305ASP A 302ASP A 274 | None | 0.73A | 1eizA-5jp9A:undetectable | 1eizA-5jp9A:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kgn | 2,3-BISPHOSPHOGLYCERATE-INDEPENDENTPHOSPHOGLYCERATEMUTASE (Caenorhabditiselegans) |
PF01676(Metalloenzyme)PF06415(iPGM_N) | 3 | ASP A 286ASP A 282ASP A 217 | GOL A 602 ( 4.8A)NoneNone | 0.76A | 1eizA-5kgnA:2.4 | 1eizA-5kgnA:18.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lkd | GLUTATHIONES-TRANSFERASEOMEGA-LIKE 2 (Saccharomycescerevisiae) |
PF13409(GST_N_2)PF13410(GST_C_2) | 3 | ASP A 129ASP A 122ASP A 340 | None | 0.65A | 1eizA-5lkdA:undetectable | 1eizA-5lkdA:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5log | PUTATIVEO-METHYLTRANSFERASE (Myxococcusxanthus) |
PF01596(Methyltransf_3) | 3 | ASP A 91ASP A 119ASP A 142 | SAH A1001 (-2.8A)SAH A1001 (-3.8A) MG A1002 (-2.5A) | 0.62A | 1eizA-5logA:14.0 | 1eizA-5logA:24.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m58 | C-METHYLTRANSFERASECOUO (Streptomycesrishiriensis) |
PF13649(Methyltransf_25) | 3 | ASP A 70ASP A 74ASP A 96 | SAH A 301 (-2.8A)NoneSAH A 301 (-3.5A) | 0.72A | 1eizA-5m58A:12.2 | 1eizA-5m58A:24.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mgz | 8-DEMETHYLNOVOBIOCICACIDC(8)-METHYLTRANSFERASE (Streptomycesniveus) |
PF13649(Methyltransf_25) | 3 | ASP A 70ASP A 74ASP A 96 | SAH A 301 (-2.8A)NoneSAH A 301 (-3.5A) | 0.70A | 1eizA-5mgzA:10.7 | 1eizA-5mgzA:24.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v88 | LYSOZYME,DCN1-LIKEPROTEIN 1 (Homo sapiens;Escherichiavirus T4) |
PF00959(Phage_lysozyme)PF03556(Cullin_binding) | 3 | ASP A1091ASP A1096ASP A1084 | None | 0.62A | 1eizA-5v88A:undetectable | 1eizA-5v88A:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wwt | PUTATIVEMETHYLTRANSFERASENSUN6 (Homo sapiens) |
PF01189(Methyltr_RsmB-F) | 3 | ASP A 266ASP A 293ASP A 323 | NoneNone C C 72 ( 2.8A) | 0.57A | 1eizA-5wwtA:10.5 | 1eizA-5wwtA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x3e | KINESIN-LIKE PROTEIN (Caenorhabditiselegans) |
PF00225(Kinesin) | 3 | ASP A 223ASP A 249ASP A 227 | NoneNoneSO4 A 519 (-4.4A) | 0.75A | 1eizA-5x3eA:undetectable | 1eizA-5x3eA:17.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x8h | SHORT-CHAINDEHYDROGENASEREDUCTASE (Chryseobacteriumsp. CA49) |
no annotation | 3 | ASP A 37ASP A 41ASP A 63 | None | 0.68A | 1eizA-5x8hA:9.9 | 1eizA-5x8hA:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xne | - (-) |
no annotation | 3 | ASP B 33ASP B 239ASP B 232 | None | 0.70A | 1eizA-5xneB:undetectable | 1eizA-5xneB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xsj | PERIPLASMIC BINDINGPROTEIN/LACITRANSCRIPTIONALREGULATOR (Clostridiumbeijerinckii) |
PF13407(Peripla_BP_4) | 3 | ASP X 105ASP X 118ASP X 108 | None | 0.78A | 1eizA-5xsjX:5.1 | 1eizA-5xsjX:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ygu | DIAMINOPIMELATEEPIMERASE (Escherichiacoli) |
no annotation | 3 | ASP A 57ASP A 53ASP A 94 | None | 0.65A | 1eizA-5yguA:undetectable | 1eizA-5yguA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zqz | TRIFUNCTIONAL ENZYMESUBUNIT ALPHA,MITOCHONDRIAL (Homo sapiens) |
no annotation | 3 | ASP A 567ASP A 572ASP A 653 | None | 0.63A | 1eizA-5zqzA:5.8 | 1eizA-5zqzA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gsa | - (-) |
no annotation | 3 | ASP E 312ASP E 320ASP E 456 | None | 0.76A | 1eizA-6gsaE:undetectable | 1eizA-6gsaE:undetectable |