SIMILAR PATTERNS OF AMINO ACIDS FOR 1E9L_A_GCSA800

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cnv CONCANAVALIN B

(Canavalia
ensiformis) 		PF00704
(Glyco_hydro_18) 		5 PHE A  35
GLY A  85
GLN A 131
TYR A 189
TRP A 265
 None
 1.01A 1e9lA-1cnvA:
19.3		 1e9lA-1cnvA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cnv CONCANAVALIN B

(Canavalia
ensiformis) 		PF00704
(Glyco_hydro_18) 		6 TYR A  10
PHE A  35
GLY A  85
ASP A 129
TYR A 189
TRP A 265
 None
 0.82A 1e9lA-1cnvA:
19.3		 1e9lA-1cnvA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d2k CHITINASE 1

(Coccidioides
immitis) 		PF00704
(Glyco_hydro_18) 		6 TYR A  43
PHE A  71
GLY A 130
ASP A 169
ASP A 240
TRP A 378
 None
 0.92A 1e9lA-1d2kA:
43.7		 1e9lA-1d2kA:
28.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d2k CHITINASE 1

(Coccidioides
immitis) 		PF00704
(Glyco_hydro_18) 		7 TYR A  43
PHE A  71
GLY A 130
ASP A 169
MET A 237
TYR A 239
ASP A 240
 None
 0.75A 1e9lA-1d2kA:
43.7		 1e9lA-1d2kA:
28.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6z CHITINASE B

(Serratia
marcescens) 		PF00704
(Glyco_hydro_18) 		6 TYR A  10
PHE A  51
GLY A  96
ASP A 142
ASP A 215
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-3.5A)
 1.01A 1e9lA-1e6zA:
42.3		 1e9lA-1e6zA:
25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6z CHITINASE B

(Serratia
marcescens) 		PF00704
(Glyco_hydro_18) 		7 TYR A  10
PHE A  51
GLY A  96
ASP A 142
MET A 212
TYR A 214
ASP A 215
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
 0.67A 1e9lA-1e6zA:
42.3		 1e9lA-1e6zA:
25.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1hjv CHITINASE-3 LIKE
PROTEIN 1

(Homo sapiens) 		PF00704
(Glyco_hydro_18) 		7 TYR A  27
PHE A  58
GLY A  98
MET A 204
TYR A 206
ASP A 207
TRP A 352
 NAG  A  -1 (-3.8A)
NAG  A  -2 (-4.7A)
NAG  A  -2 ( 4.2A)
NAG  A   1 (-3.7A)
NAG  A  -1 (-4.6A)
NAG  A  -1 (-3.7A)
NAG  A  -1 (-3.5A)
 0.84A 1e9lA-1hjvA:
54.3		 1e9lA-1hjvA:
46.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1hkk CHITOTRIOSIDASE-1

(Homo sapiens) 		PF00704
(Glyco_hydro_18) 		7 TYR A  27
PHE A  58
GLY A  98
ASP A 138
MET A 210
ASP A 213
TRP A 358
 AMI  A1388 (-3.6A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 3.7A)
AMI  A1388 (-3.1A)
AMI  A1388 (-3.3A)
AMI  A1388 ( 2.9A)
AMI  A1388 (-3.5A)
 1.06A 1e9lA-1hkkA:
58.2		 1e9lA-1hkkA:
48.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1hkk CHITOTRIOSIDASE-1

(Homo sapiens) 		PF00704
(Glyco_hydro_18) 		7 TYR A  27
PHE A  58
GLY A  98
ASP A 138
MET A 210
TYR A 212
ASP A 213
 AMI  A1388 (-3.6A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 3.7A)
AMI  A1388 (-3.1A)
AMI  A1388 (-3.3A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 2.9A)
 0.90A 1e9lA-1hkkA:
58.2		 1e9lA-1hkkA:
48.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1itx GLYCOSYL HYDROLASE

(Bacillus
circulans) 		PF00704
(Glyco_hydro_18) 		6 TYR A  49
PHE A  77
GLY A 163
ASP A 202
ASP A 280
TRP A 433
 GOL  A1007 (-4.1A)
GOL  A1007 (-4.8A)
GOL  A1007 ( 3.9A)
GOL  A1007 (-3.6A)
None
GOL  A1007 (-4.8A)
 0.95A 1e9lA-1itxA:
47.6		 1e9lA-1itxA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1itx GLYCOSYL HYDROLASE

(Bacillus
circulans) 		PF00704
(Glyco_hydro_18) 		7 TYR A  49
PHE A  77
GLY A 163
ASP A 202
MET A 277
TYR A 279
ASP A 280
 GOL  A1007 (-4.1A)
GOL  A1007 (-4.8A)
GOL  A1007 ( 3.9A)
GOL  A1007 (-3.6A)
GOL  A1007 ( 3.3A)
GOL  A1007 ( 4.8A)
None
 0.65A 1e9lA-1itxA:
47.6		 1e9lA-1itxA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfw CHITINASE B

(Arthrobacter
sp. TAD20) 		PF00704
(Glyco_hydro_18) 		7 TYR A  23
PHE A  55
GLY A 135
ASP A 190
TYR A 271
ASP A 272
TRP A 412
 None
None
None
None
GOL  A 530 (-4.8A)
GOL  A 530 (-3.7A)
None
 0.83A 1e9lA-1kfwA:
43.8		 1e9lA-1kfwA:
25.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1vf8 SECRETORY PROTEIN

(Mus musculus) 		PF00704
(Glyco_hydro_18) 		9 TYR A   6
PHE A  37
GLY A  77
ASP A 117
GLN A 119
MET A 189
TYR A 191
ASP A 192
TRP A 339
 None
 0.57A 1e9lA-1vf8A:
64.1		 1e9lA-1vf8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1wb0 CHITOTRIOSIDASE 1

(Homo sapiens) 		PF00704
(Glyco_hydro_18) 		7 TYR A  27
PHE A  58
GLY A  98
ASP A 138
MET A 210
ASP A 213
TRP A 360
 None
 0.96A 1e9lA-1wb0A:
58.0		 1e9lA-1wb0A:
41.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1wb0 CHITOTRIOSIDASE 1

(Homo sapiens) 		PF00704
(Glyco_hydro_18) 		7 TYR A  27
PHE A  58
GLY A  98
ASP A 138
MET A 210
TYR A 212
ASP A 213
 None
 0.80A 1e9lA-1wb0A:
58.0		 1e9lA-1wb0A:
41.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wno CHITINASE

(Aspergillus
fumigatus) 		PF00704
(Glyco_hydro_18) 		8 TYR A  10
PHE A  38
GLY A  98
ASP A 137
MET A 205
TYR A 207
ASP A 208
TRP A 346
 None
 0.82A 1e9lA-1wnoA:
42.9		 1e9lA-1wnoA:
26.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wk2 CHITINASE A

(Serratia
marcescens) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		6 TYR A 163
PHE A 191
GLY A 274
ASP A 313
ASP A 391
TRP A 539
 NGT  A1565 (-3.6A)
SN5  A1564 (-4.6A)
NGT  A1565 ( 3.9A)
NGT  A1565 (-3.4A)
NGT  A1565 (-2.9A)
NGT  A1565 ( 3.5A)
 0.95A 1e9lA-2wk2A:
42.4		 1e9lA-2wk2A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wk2 CHITINASE A

(Serratia
marcescens) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		7 TYR A 163
PHE A 191
GLY A 274
ASP A 313
MET A 388
TYR A 390
ASP A 391
 NGT  A1565 (-3.6A)
SN5  A1564 (-4.6A)
NGT  A1565 ( 3.9A)
NGT  A1565 (-3.4A)
NGT  A1565 (-3.7A)
NGT  A1565 (-4.7A)
NGT  A1565 (-2.9A)
 0.78A 1e9lA-2wk2A:
42.4		 1e9lA-2wk2A:
21.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ybu ACIDIC MAMMALIAN
CHITINASE

(Homo sapiens) 		PF00704
(Glyco_hydro_18) 		6 TYR A  27
PHE A  58
GLY A  98
ASP A 138
ASP A 213
TRP A 360
 None
CX9  A1398 (-4.5A)
CX9  A1398 (-3.5A)
CX9  A1398 (-3.0A)
CX9  A1398 ( 4.4A)
CX9  A1398 ( 3.3A)
 0.89A 1e9lA-2ybuA:
61.2		 1e9lA-2ybuA:
67.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ybu ACIDIC MAMMALIAN
CHITINASE

(Homo sapiens) 		PF00704
(Glyco_hydro_18) 		7 TYR A  27
PHE A  58
GLY A  98
ASP A 138
MET A 210
TYR A 212
ASP A 213
 None
CX9  A1398 (-4.5A)
CX9  A1398 (-3.5A)
CX9  A1398 (-3.0A)
CX9  A1398 (-3.3A)
CX9  A1398 (-4.3A)
CX9  A1398 ( 4.4A)
 0.69A 1e9lA-2ybuA:
61.2		 1e9lA-2ybuA:
67.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3alf CHITINASE, CLASS V

(Nicotiana
tabacum) 		PF00704
(Glyco_hydro_18) 		8 TYR A   7
PHE A  31
GLY A  73
ASP A 113
MET A 181
TYR A 183
ASP A 184
TRP A 326
 EDO  A 357 ( 4.5A)
EDO  A 357 (-4.8A)
EDO  A 357 ( 4.2A)
EDO  A 357 (-4.2A)
EDO  A 357 ( 3.3A)
EDO  A 359 ( 4.7A)
EDO  A 359 (-4.5A)
EDO  A 357 (-4.4A)
 0.88A 1e9lA-3alfA:
45.9		 1e9lA-3alfA:
28.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3aqu AT4G19810

(Arabidopsis
thaliana) 		PF00704
(Glyco_hydro_18) 		6 TYR A   8
PHE A  32
GLY A  74
ASP A 114
ASP A 185
TRP A 324
 None
 0.96A 1e9lA-3aquA:
44.8		 1e9lA-3aquA:
30.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3aqu AT4G19810

(Arabidopsis
thaliana) 		PF00704
(Glyco_hydro_18) 		7 TYR A   8
PHE A  32
GLY A  74
ASP A 114
MET A 182
TYR A 184
ASP A 185
 None
 0.77A 1e9lA-3aquA:
44.8		 1e9lA-3aquA:
30.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9e CHITINASE A

(Vibrio harveyi) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		6 TYR A 164
PHE A 192
GLY A 274
ASP A 313
ASP A 392
TRP A 570
 None
 0.98A 1e9lA-3b9eA:
18.8		 1e9lA-3b9eA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9e CHITINASE A

(Vibrio harveyi) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		7 TYR A 164
PHE A 192
GLY A 274
ASP A 313
MET A 389
TYR A 391
ASP A 392
 None
 0.81A 1e9lA-3b9eA:
18.8		 1e9lA-3b9eA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ebv CHINITASE A

(Streptomyces
coelicolor) 		PF00704
(Glyco_hydro_18) 		5 TYR A  10
PHE A  37
GLY A  84
ASP A 119
TRP A 271
 None
 0.76A 1e9lA-3ebvA:
21.4		 1e9lA-3ebvA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ebv CHINITASE A

(Streptomyces
coelicolor) 		PF00704
(Glyco_hydro_18) 		5 TYR A  10
PHE A  37
GLY A  84
ASP A 119
TYR A 181
 None
 0.71A 1e9lA-3ebvA:
21.4		 1e9lA-3ebvA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fnd CHITINASE

(Bacteroides
thetaiotaomicron) 		PF00704
(Glyco_hydro_18) 		6 TYR A  52
PHE A  79
ASP A 155
MET A 211
ASP A 214
TRP A 322
 None
 1.02A 1e9lA-3fndA:
31.5		 1e9lA-3fndA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fnd CHITINASE

(Bacteroides
thetaiotaomicron) 		PF00704
(Glyco_hydro_18) 		6 TYR A  52
PHE A  79
ASP A 155
MET A 211
TYR A 213
ASP A 214
 None
 0.88A 1e9lA-3fndA:
31.5		 1e9lA-3fndA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g6l CHITINASE

(Clonostachys
rosea) 		PF00704
(Glyco_hydro_18) 		6 TYR A  46
PHE A  74
GLY A 133
ASP A 172
ASP A 243
TRP A 381
 None
 1.00A 1e9lA-3g6lA:
43.5		 1e9lA-3g6lA:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g6l CHITINASE

(Clonostachys
rosea) 		PF00704
(Glyco_hydro_18) 		7 TYR A  46
PHE A  74
GLY A 133
ASP A 172
MET A 240
TYR A 242
ASP A 243
 None
 0.75A 1e9lA-3g6lA:
43.5		 1e9lA-3g6lA:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qok PUTATIVE CHITINASE
II

(Klebsiella
pneumoniae) 		PF00704
(Glyco_hydro_18) 		6 TYR A  28
PHE A  58
GLY A 113
ASP A 151
ASP A 223
TRP A 395
 None
 1.03A 1e9lA-3qokA:
39.5		 1e9lA-3qokA:
28.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qok PUTATIVE CHITINASE
II

(Klebsiella
pneumoniae) 		PF00704
(Glyco_hydro_18) 		7 TYR A  28
PHE A  58
GLY A 113
ASP A 151
MET A 220
TYR A 222
ASP A 223
 None
 0.69A 1e9lA-3qokA:
39.5		 1e9lA-3qokA:
28.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w4r CHITINASE

(Ostrinia
furnacalis) 		PF00704
(Glyco_hydro_18) 		7 TYR A  30
PHE A  61
GLY A 106
ASP A 146
MET A 215
ASP A 218
TRP A 372
 None
 1.03A 1e9lA-3w4rA:
53.8		 1e9lA-3w4rA:
28.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w4r CHITINASE

(Ostrinia
furnacalis) 		PF00704
(Glyco_hydro_18) 		7 TYR A  30
PHE A  61
GLY A 106
ASP A 146
MET A 215
TYR A 217
ASP A 218
 None
 0.84A 1e9lA-3w4rA:
53.8		 1e9lA-3w4rA:
28.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3wl1 CHITINASE

(Ostrinia
furnacalis) 		PF00704
(Glyco_hydro_18) 		8 TYR A  30
PHE A  61
GLY A 106
ASP A 146
MET A 215
TYR A 217
ASP A 218
TRP A 372
 NAG  A 501 (-3.8A)
NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 501 (-3.0A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 ( 3.2A)
NAG  A 501 (-3.7A)
 0.98A 1e9lA-3wl1A:
53.8		 1e9lA-3wl1A:
37.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a5q CHI1

(Yersinia
entomophaga) 		PF00704
(Glyco_hydro_18) 		7 PHE A 117
GLY A 214
ASP A 254
MET A 323
TYR A 325
ASP A 326
TRP A 486
 None
 1.12A 1e9lA-4a5qA:
33.5		 1e9lA-4a5qA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a5q CHI1

(Yersinia
entomophaga) 		PF00704
(Glyco_hydro_18) 		7 TYR A  73
PHE A 117
GLY A 214
ASP A 254
TYR A 325
ASP A 326
TRP A 486
 None
 0.98A 1e9lA-4a5qA:
33.5		 1e9lA-4a5qA:
23.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ay1 CHITINASE-3-LIKE
PROTEIN 2

(Homo sapiens) 		PF00704
(Glyco_hydro_18) 		5 TYR A  32
PHE A  63
GLY A 103
ASP A 213
TRP A 360
 NAG  A 401 (-3.9A)
None
NAG  A 401 (-3.5A)
NAG  A 401 (-2.8A)
NAG  A 401 (-3.7A)
 0.87A 1e9lA-4ay1A:
54.1		 1e9lA-4ay1A:
43.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dws CHI2

(Yersinia
entomophaga) 		PF00704
(Glyco_hydro_18) 		7 PHE A 200
GLY A 307
ASP A 347
MET A 422
TYR A 424
ASP A 425
TRP A 582
 None
None
None
None
None
None
GOL  A 701 (-4.2A)
 0.73A 1e9lA-4dwsA:
33.8		 1e9lA-4dwsA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dws CHI2

(Yersinia
entomophaga) 		PF00704
(Glyco_hydro_18) 		7 TYR A 156
PHE A 200
GLY A 307
ASP A 347
TYR A 424
ASP A 425
TRP A 582
 None
None
None
None
None
None
GOL  A 701 (-4.2A)
 0.64A 1e9lA-4dwsA:
33.8		 1e9lA-4dwsA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mb5 CHITINASE 60

(Moritella
marina) 		PF00704
(Glyco_hydro_18)
PF16403
(DUF5011) 		5 PHE A  70
GLY A 117
ASP A 151
GLN A 153
TRP A 311
 NAG  A 608 (-4.4A)
NAG  A 608 ( 3.9A)
NAG  A 608 (-3.4A)
NAG  A 609 (-3.0A)
NAG  A 608 (-3.5A)
 0.84A 1e9lA-4mb5A:
19.8		 1e9lA-4mb5A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mb5 CHITINASE 60

(Moritella
marina) 		PF00704
(Glyco_hydro_18)
PF16403
(DUF5011) 		5 PHE A  70
GLY A 117
ASP A 151
GLN A 153
TYR A 220
 NAG  A 608 (-4.4A)
NAG  A 608 ( 3.9A)
NAG  A 608 (-3.4A)
NAG  A 609 (-3.0A)
NAG  A 609 (-4.4A)
 0.78A 1e9lA-4mb5A:
19.8		 1e9lA-4mb5A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mb5 CHITINASE 60

(Moritella
marina) 		PF00704
(Glyco_hydro_18)
PF16403
(DUF5011) 		5 TYR A  36
PHE A  70
GLY A 117
ASP A 151
TRP A 311
 NAG  A 608 ( 3.8A)
NAG  A 608 (-4.4A)
NAG  A 608 ( 3.9A)
NAG  A 608 (-3.4A)
NAG  A 608 (-3.5A)
 0.82A 1e9lA-4mb5A:
19.8		 1e9lA-4mb5A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mb5 CHITINASE 60

(Moritella
marina) 		PF00704
(Glyco_hydro_18)
PF16403
(DUF5011) 		5 TYR A  36
PHE A  70
GLY A 117
ASP A 151
TYR A 220
 NAG  A 608 ( 3.8A)
NAG  A 608 (-4.4A)
NAG  A 608 ( 3.9A)
NAG  A 608 (-3.4A)
NAG  A 609 (-4.4A)
 0.73A 1e9lA-4mb5A:
19.8		 1e9lA-4mb5A:
22.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4mnm CHITINASE A

(Cycas revoluta) 		PF00704
(Glyco_hydro_18) 		7 PHE A  34
GLY A  76
ASP A 117
GLN A 119
MET A 189
ASP A 192
TRP A 327
 None
 0.95A 1e9lA-4mnmA:
45.0		 1e9lA-4mnmA:
31.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4mnm CHITINASE A

(Cycas revoluta) 		PF00704
(Glyco_hydro_18) 		7 PHE A  34
GLY A  76
ASP A 117
GLN A 119
MET A 189
TYR A 191
ASP A 192
 None
 0.81A 1e9lA-4mnmA:
45.0		 1e9lA-4mnmA:
31.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n42 XYLANASE AND
ALPHA-AMYLASE
INHIBITOR PROTEIN
ISOFORM III

(Scadoxus
multiflorus) 		PF00704
(Glyco_hydro_18) 		5 TYR A   8
PHE A  34
GLY A  76
TYR A 181
TRP A 253
 None
 0.91A 1e9lA-4n42A:
19.0		 1e9lA-4n42A:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q22 GLYCOSIDE HYDROLASE
FAMILY 18

(Serratia
proteamaculans) 		PF00704
(Glyco_hydro_18) 		6 TYR A  28
PHE A  58
GLY A 113
ASP A 151
ASP A 223
TRP A 395
 ACT  A 502 (-3.4A)
None
ACT  A 502 ( 4.6A)
ACT  A 502 (-3.0A)
GOL  A 504 (-2.7A)
GOL  A 504 (-3.7A)
 1.10A 1e9lA-4q22A:
39.3		 1e9lA-4q22A:
29.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q22 GLYCOSIDE HYDROLASE
FAMILY 18

(Serratia
proteamaculans) 		PF00704
(Glyco_hydro_18) 		7 TYR A  28
PHE A  58
GLY A 113
ASP A 151
MET A 220
TYR A 222
ASP A 223
 ACT  A 502 (-3.4A)
None
ACT  A 502 ( 4.6A)
ACT  A 502 (-3.0A)
ACT  A 502 ( 3.1A)
GOL  A 504 ( 4.6A)
GOL  A 504 (-2.7A)
 0.91A 1e9lA-4q22A:
39.3		 1e9lA-4q22A:
29.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r12 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Dictyostelium
purpureum) 		PF05450
(Nicastrin) 		5 GLY A 431
ASP A 127
GLN A 254
ASP A 240
TRP A 291
 None
 1.26A 1e9lA-4r12A:
undetectable		 1e9lA-4r12A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rl3 CHITINASE A

(Pteris
ryukyuensis) 		PF00704
(Glyco_hydro_18) 		5 TYR A 130
PHE A 157
GLY A 204
ASP A 245
TYR A 308
 ACT  A 403 (-3.9A)
None
None
ACT  A 403 (-2.7A)
ACT  A 403 (-4.5A)
 0.68A 1e9lA-4rl3A:
6.7		 1e9lA-4rl3A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s3j CORTICAL-LYTIC
ENZYME

(Bacillus cereus) 		PF00704
(Glyco_hydro_18)
PF01476
(LysM) 		5 PHE A 138
ASP A 217
MET A 281
TYR A 283
ASP A 284
 None
 1.01A 1e9lA-4s3jA:
31.2		 1e9lA-4s3jA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s3j CORTICAL-LYTIC
ENZYME

(Bacillus cereus) 		PF00704
(Glyco_hydro_18)
PF01476
(LysM) 		5 TYR A 109
ASP A 217
MET A 281
TYR A 283
ASP A 284
 None
 0.81A 1e9lA-4s3jA:
31.2		 1e9lA-4s3jA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4toq CLASS III CHITINASE

(Punica granatum) 		PF00704
(Glyco_hydro_18) 		5 TYR A   6
PHE A  32
GLY A  80
ASP A 125
TYR A 183
 None
 0.73A 1e9lA-4toqA:
19.0		 1e9lA-4toqA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4txg CHITINASE

(Chromobacterium
violaceum) 		PF00704
(Glyco_hydro_18)
PF06483
(ChiC) 		6 TYR A 159
PHE A 190
GLY A 254
ASP A 312
ASP A 398
TRP A 603
 None
None
None
None
CS  A 812 (-4.0A)
CS  A 812 ( 4.2A)
 0.96A 1e9lA-4txgA:
34.4		 1e9lA-4txgA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4txg CHITINASE

(Chromobacterium
violaceum) 		PF00704
(Glyco_hydro_18)
PF06483
(ChiC) 		7 TYR A 159
PHE A 190
GLY A 254
ASP A 312
MET A 395
TYR A 397
ASP A 398
 None
None
None
None
CS  A 803 (-3.5A)
CS  A 812 (-4.4A)
CS  A 812 (-4.0A)
 0.68A 1e9lA-4txgA:
34.4		 1e9lA-4txgA:
20.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4uri CHITINASE-RELATED
AGGLUTININ

(Robinia
pseudoacacia) 		PF00704
(Glyco_hydro_18) 		5 TYR A   6
GLY A  73
MET A 183
TYR A 185
TRP A 317
 MPD  A 401 (-3.5A)
MPD  A 401 (-3.9A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
MPD  A 401 (-3.8A)
 1.24A 1e9lA-4uriA:
44.0		 1e9lA-4uriA:
31.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4uri CHITINASE-RELATED
AGGLUTININ

(Robinia
pseudoacacia) 		PF00704
(Glyco_hydro_18) 		7 TYR A   6
PHE A  30
GLY A  72
ASP A 114
MET A 183
TYR A 185
TRP A 317
 MPD  A 401 (-3.5A)
None
MPD  A 401 ( 4.6A)
MPD  A 401 (-4.3A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
MPD  A 401 (-3.8A)
 0.92A 1e9lA-4uriA:
44.0		 1e9lA-4uriA:
31.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4uri CHITINASE-RELATED
AGGLUTININ

(Robinia
pseudoacacia) 		PF00704
(Glyco_hydro_18) 		7 TYR A   6
PHE A  30
GLY A  72
MET A 183
TYR A 185
ASP A 186
TRP A 317
 MPD  A 401 (-3.5A)
None
MPD  A 401 ( 4.6A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
None
MPD  A 401 (-3.8A)
 0.85A 1e9lA-4uriA:
44.0		 1e9lA-4uriA:
31.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w5u CHITINASE

(Streptomyces
thermoviolaceus) 		no annotation 8 TYR B  46
PHE B  78
GLY B 141
ASP B 181
MET B 248
TYR B 250
ASP B 251
TRP B 388
 None
None
None
None
None
None
MLI  B 501 ( 4.7A)
None
 0.65A 1e9lA-4w5uB:
42.1		 1e9lA-4w5uB:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wiw GLYCOSIDE HYDROLASE
FAMILY 18

(Desulfitobacterium
hafniense) 		PF00704
(Glyco_hydro_18) 		5 TYR A 348
ASP A 458
MET A 530
TYR A 532
ASP A 533
 None
CA  A 704 ( 4.4A)
CA  A 704 ( 4.4A)
None
None
 0.95A 1e9lA-4wiwA:
30.9		 1e9lA-4wiwA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5df0 AC-CHIA

(Autographa
californica
multiple
nucleopolyhedrovirus) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		6 TYR A 153
PHE A 181
GLY A 264
ASP A 303
ASP A 382
TRP A 528
 58Y  A 605 (-3.6A)
58Y  A 605 (-4.5A)
58Y  A 605 ( 4.2A)
None
58Y  A 605 ( 3.0A)
58Y  A 605 (-3.7A)
 1.07A 1e9lA-5df0A:
42.1		 1e9lA-5df0A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5df0 AC-CHIA

(Autographa
californica
multiple
nucleopolyhedrovirus) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		7 TYR A 153
PHE A 181
GLY A 264
ASP A 303
MET A 379
TYR A 381
ASP A 382
 58Y  A 605 (-3.6A)
58Y  A 605 (-4.5A)
58Y  A 605 ( 4.2A)
None
58Y  A 605 (-3.3A)
58Y  A 605 (-4.9A)
58Y  A 605 ( 3.0A)
 0.82A 1e9lA-5df0A:
42.1		 1e9lA-5df0A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gpr CHITINASE

(Ostrinia
furnacalis) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		8 TYR A 156
PHE A 184
GLY A 267
ASP A 306
MET A 381
TYR A 383
ASP A 384
TRP A 532
 TYR  A 156 ( 1.3A)
PHE  A 184 ( 1.3A)
GLY  A 267 ( 0.0A)
ASP  A 306 ( 0.5A)
MET  A 381 ( 0.0A)
TYR  A 383 ( 1.3A)
ASP  A 384 ( 0.5A)
TRP  A 532 ( 0.5A)
 0.84A 1e9lA-5gprA:
42.6		 1e9lA-5gprA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzt CHITINASE

(Paenibacillus
sp. FPU-7) 		PF00704
(Glyco_hydro_18) 		6 TYR B 564
PHE B 590
GLY B 651
ASP B 689
ASP B 767
TRP B 905
 None
 1.02A 1e9lA-5gztB:
43.1		 1e9lA-5gztB:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzt CHITINASE

(Paenibacillus
sp. FPU-7) 		PF00704
(Glyco_hydro_18) 		7 TYR B 564
PHE B 590
GLY B 651
ASP B 689
MET B 764
TYR B 766
ASP B 767
 None
 0.73A 1e9lA-5gztB:
43.1		 1e9lA-5gztB:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzt CHITINASE

(Paenibacillus
sp. FPU-7) 		PF00704
(Glyco_hydro_18) 		6 TYR B1051
PHE B1077
GLY B1137
ASP B1175
ASP B1253
TRP B1396
 None
 1.03A 1e9lA-5gztB:
43.1		 1e9lA-5gztB:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzt CHITINASE

(Paenibacillus
sp. FPU-7) 		PF00704
(Glyco_hydro_18) 		7 TYR B1051
PHE B1077
GLY B1137
ASP B1175
MET B1250
TYR B1252
ASP B1253
 None
 0.87A 1e9lA-5gztB:
43.1		 1e9lA-5gztB:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzu CHITINASE

(Paenibacillus
sp. FPU-7) 		PF00704
(Glyco_hydro_18) 		6 TYR A 564
PHE A 590
GLY A 651
ASP A 689
ASP A 767
TRP A 905
 None
 1.00A 1e9lA-5gzuA:
43.3		 1e9lA-5gzuA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzu CHITINASE

(Paenibacillus
sp. FPU-7) 		PF00704
(Glyco_hydro_18) 		7 TYR A 564
PHE A 590
GLY A 651
ASP A 689
MET A 764
TYR A 766
ASP A 767
 None
 0.71A 1e9lA-5gzuA:
43.3		 1e9lA-5gzuA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzu CHITINASE

(Paenibacillus
sp. FPU-7) 		PF00704
(Glyco_hydro_18) 		6 TYR A1051
PHE A1077
GLY A1137
ASP A1175
ASP A1253
TRP A1396
 None
 1.03A 1e9lA-5gzuA:
43.3		 1e9lA-5gzuA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzu CHITINASE

(Paenibacillus
sp. FPU-7) 		PF00704
(Glyco_hydro_18) 		7 TYR A1051
PHE A1077
GLY A1137
ASP A1175
MET A1250
TYR A1252
ASP A1253
 None
 0.89A 1e9lA-5gzuA:
43.3		 1e9lA-5gzuA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jh8 PROBABLE CHITINASE

(Chromobacterium
violaceum) 		PF00704
(Glyco_hydro_18) 		5 TYR A   5
ASP A 109
MET A 174
TYR A 176
ASP A 177
 HIS  A 505 ( 4.1A)
HIS  A 505 (-2.3A)
HIS  A 505 (-3.8A)
6KY  A 504 (-4.0A)
6KY  A 504 (-2.6A)
 0.78A 1e9lA-5jh8A:
32.5		 1e9lA-5jh8A:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wvb CHITINASE

(Ostrinia
furnacalis) 		no annotation 8 TYR A  98
PHE A 129
GLY A 175
ASP A 215
MET A 283
TYR A 285
ASP A 286
TRP A 433
 NAG  A 504 (-3.7A)
NAG  A 505 (-4.5A)
NAG  A 504 (-3.7A)
NAG  A 504 (-3.8A)
NAG  A 503 (-4.0A)
NAG  A 504 (-4.5A)
NAG  A 504 (-3.5A)
NAG  A 504 (-3.6A)
 0.79A 1e9lA-5wvbA:
57.3		 1e9lA-5wvbA:
13.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5wvg CHITINASE

(Ostrinia
furnacalis) 		no annotation 7 TYR A 534
PHE A 565
GLY A 605
ASP A 645
MET A 713
ASP A 716
TRP A 864
 NAG  A1003 ( 4.2A)
NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1003 (-3.9A)
NAG  A1003 (-3.6A)
NAG  A1003 (-3.1A)
NAG  A1003 (-3.4A)
 0.96A 1e9lA-5wvgA:
55.8		 1e9lA-5wvgA:
47.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5wvg CHITINASE

(Ostrinia
furnacalis) 		no annotation 7 TYR A 534
PHE A 565
GLY A 605
ASP A 645
MET A 713
TYR A 715
ASP A 716
 NAG  A1003 ( 4.2A)
NAG  A1003 ( 4.8A)
NAG  A1003 (-3.5A)
NAG  A1003 (-3.9A)
NAG  A1003 (-3.6A)
NAG  A1003 (-4.5A)
NAG  A1003 (-3.1A)
 0.82A 1e9lA-5wvgA:
55.8		 1e9lA-5wvgA:
47.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xep CHITINASE-3-LIKE
PROTEIN 1

(Mus musculus) 		no annotation 6 TYR A  27
PHE A  58
GLY A  99
MET A 205
TYR A 207
TRP A 353
 None
 0.84A 1e9lA-5xepA:
54.1		 1e9lA-5xepA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xwq FUNGAL CHITINASE
FROM RHIZOMUCOR
MIEHEI (NATIVE
PROTEIN)

(Rhizomucor
miehei) 		no annotation 7 TYR A  82
PHE A 104
GLY A 141
ASP A 180
MET A 254
ASP A 257
TRP A 425
 None
 0.93A 1e9lA-5xwqA:
38.1		 1e9lA-5xwqA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xwq FUNGAL CHITINASE
FROM RHIZOMUCOR
MIEHEI (NATIVE
PROTEIN)

(Rhizomucor
miehei) 		no annotation 7 TYR A  82
PHE A 104
GLY A 141
ASP A 180
MET A 254
TYR A 256
ASP A 257
 None
 0.77A 1e9lA-5xwqA:
38.1		 1e9lA-5xwqA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y29 INSECT GROUP II
CHITINASE

(Ostrinia
furnacalis) 		no annotation 6 TYR A1617
PHE A1648
GLY A1690
ASP A1731
ASP A1804
TRP A1961
 None
 0.94A 1e9lA-5y29A:
52.1		 1e9lA-5y29A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y29 INSECT GROUP II
CHITINASE

(Ostrinia
furnacalis) 		no annotation 7 TYR A1617
PHE A1648
GLY A1690
ASP A1731
MET A1801
TYR A1803
ASP A1804
 None
 0.83A 1e9lA-5y29A:
52.1		 1e9lA-5y29A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y2a INSECT GROUP II
CHITINASE

(Ostrinia
furnacalis) 		no annotation 8 TYR A2063
PHE A2094
GLY A2137
ASP A2178
MET A2248
TYR A2250
ASP A2251
TRP A2398
 None
 0.75A 1e9lA-5y2aA:
52.7		 1e9lA-5y2aA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zl9 CHITINASE AB

(Serratia
marcescens) 		no annotation 6 TYR A 163
PHE A 191
GLY A 274
ASP A 313
ASP A 393
TRP A 541
 GOL  A 706 (-4.1A)
GOL  A 706 (-4.9A)
GOL  A 706 ( 4.1A)
GOL  A 706 (-3.5A)
GOL  A 703 (-3.0A)
GOL  A 706 ( 3.8A)
 0.98A 1e9lA-5zl9A:
42.2		 1e9lA-5zl9A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zl9 CHITINASE AB

(Serratia
marcescens) 		no annotation 7 TYR A 163
PHE A 191
GLY A 274
ASP A 313
MET A 390
TYR A 392
ASP A 393
 GOL  A 706 (-4.1A)
GOL  A 706 (-4.9A)
GOL  A 706 ( 4.1A)
GOL  A 706 (-3.5A)
GOL  A 706 (-3.3A)
GOL  A 706 (-4.8A)
GOL  A 703 (-3.0A)
 0.68A 1e9lA-5zl9A:
42.2		 1e9lA-5zl9A:
11.99