SIMILAR PATTERNS OF AMINO ACIDS FOR 1E7C_A_HLTA4008_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aql | BILE-SALT ACTIVATEDLIPASE (Bos taurus) |
PF00135(COesterase) | 4 | LEU A 258LEU A 234ALA A 237LYS A 238 | None | 0.68A | 1e7cA-1aqlA:0.0 | 1e7cA-1aqlA:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1atj | PEROXIDASE C1A (Armoraciarusticana) |
PF00141(peroxidase) | 4 | ALA A 51LEU A 100LEU A 101LYS A 84 | None | 0.80A | 1e7cA-1atjA:0.7 | 1e7cA-1atjA:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bkh | MUCONATE LACTONIZINGENZYME (Pseudomonasputida) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ALA A 193LYS A 186LEU A 189LEU A 158ALA A 154 | None | 1.38A | 1e7cA-1bkhA:0.0 | 1e7cA-1bkhA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c8x | ENDO-BETA-N-ACETYLGLUCOSAMINIDASE H (Streptomycesplicatus) |
PF00704(Glyco_hydro_18) | 4 | ALA A 46LEU A 59LEU A 88ALA A 118 | ALA A 46 ( 0.0A)LEU A 59 ( 0.6A)LEU A 88 ( 0.5A)ALA A 118 ( 0.0A) | 0.79A | 1e7cA-1c8xA:0.0 | 1e7cA-1c8xA:16.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cwu | ENOYL ACP REDUCTASE (Brassica napus) |
PF13561(adh_short_C2) | 4 | ALA A 24LEU A 137LEU A 169ALA A 90 | NoneNAD A 501 (-3.9A)NoneNAD A 501 (-3.9A) | 0.80A | 1e7cA-1cwuA:undetectable | 1e7cA-1cwuA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1db3 | GDP-MANNOSE4,6-DEHYDRATASE (Escherichiacoli) |
PF16363(GDP_Man_Dehyd) | 4 | LEU A 211LEU A 350ALA A 353LYS A 354 | None | 0.75A | 1e7cA-1db3A:undetectable | 1e7cA-1db3A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e6w | SHORT CHAIN3-HYDROXYACYL-COADEHYDROGENASE (Rattusnorvegicus) |
PF00106(adh_short) | 4 | LEU A 39LEU A 24ALA A 27LYS A 28 | None | 0.70A | 1e7cA-1e6wA:0.0 | 1e7cA-1e6wA:18.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g4u | PROTEIN TYROSINEPHOSPHATASE SPTP (Salmonellaenterica) |
PF00102(Y_phosphatase)PF03545(YopE) | 5 | LEU S 183LEU S 186ALA S 277LYS S 278LYS S 281 | None | 1.39A | 1e7cA-1g4uS:2.7 | 1e7cA-1g4uS:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g8p | MAGNESIUM-CHELATASE38 KDA SUBUNIT (Rhodobactercapsulatus) |
PF01078(Mg_chelatase) | 4 | ALA A 272LEU A 315LEU A 295ALA A 298 | None | 0.73A | 1e7cA-1g8pA:0.0 | 1e7cA-1g8pA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gk2 | HISTIDINEAMMONIA-LYASE (Pseudomonasputida) |
PF00221(Lyase_aromatic) | 4 | ALA A 204LEU A 341LEU A 303ALA A 299 | None | 0.80A | 1e7cA-1gk2A:2.1 | 1e7cA-1gk2A:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gwc | GLUTATHIONES-TRANSFERASE TSI-1 (Aegilopstauschii) |
PF00043(GST_C)PF02798(GST_N) | 5 | ALA A 177LEU A 215LEU A 216LEU A 178ALA A 219 | None | 1.26A | 1e7cA-1gwcA:3.6 | 1e7cA-1gwcA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gwc | GLUTATHIONES-TRANSFERASE TSI-1 (Aegilopstauschii) |
PF00043(GST_C)PF02798(GST_N) | 4 | ALA A 177LEU A 216ALA A 219LYS A 220 | None | 0.75A | 1e7cA-1gwcA:3.6 | 1e7cA-1gwcA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hrd | GLUTAMATEDEHYDROGENASE ([Clostridium]symbiosum) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 5 | ALA A 245LEU A 259LEU A 235LEU A 249ALA A 256 | None | 1.44A | 1e7cA-1hrdA:undetectable | 1e7cA-1hrdA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i2o | TRANSALDOLASE B (Escherichiacoli) |
PF00923(TAL_FSA) | 4 | ALA A 112LEU A 133LEU A 146ALA A 142 | None | 0.80A | 1e7cA-1i2oA:undetectable | 1e7cA-1i2oA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ia7 | CELLULASE CEL9M ([Clostridium]cellulolyticum) |
PF00759(Glyco_hydro_9) | 4 | ALA A 223LEU A 181ALA A 184LYS A 185 | None | 0.66A | 1e7cA-1ia7A:0.9 | 1e7cA-1ia7A:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1igw | ISOCITRATE LYASE (Escherichiacoli) |
PF00463(ICL) | 4 | ALA A 131LEU A 78ALA A 81LYS A 82 | None | 0.77A | 1e7cA-1igwA:undetectable | 1e7cA-1igwA:20.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iho | PANTOATE--BETA-ALANINE LIGASE (Escherichiacoli) |
PF02569(Pantoate_ligase) | 5 | ALA A 272LEU A 204LEU A 269LEU A 193ALA A 201 | None | 1.39A | 1e7cA-1ihoA:undetectable | 1e7cA-1ihoA:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iw8 | ACID PHOSPHATASE (Shimwelliablattae) |
PF01569(PAP2) | 5 | LEU A 95LEU A 98LEU A 218ALA A 221LYS A 222 | None | 1.18A | 1e7cA-1iw8A:undetectable | 1e7cA-1iw8A:18.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jmy | BILE-SALT-ACTIVATEDLIPASE (Homo sapiens) |
PF00135(COesterase) | 5 | ALA A 251LEU A 258LEU A 234ALA A 237LYS A 238 | None | 1.18A | 1e7cA-1jmyA:undetectable | 1e7cA-1jmyA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k1c | CATABOLITEREPRESSION HPR-LIKEPROTEIN (Bacillussubtilis) |
PF00381(PTS-HPr) | 4 | ALA A 73LEU A 63ALA A 44LYS A 45 | None | 0.78A | 1e7cA-1k1cA:undetectable | 1e7cA-1k1cA:10.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kfi | PHOSPHOGLUCOMUTASE 1 (Parameciumtetraurelia) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I)PF02879(PGM_PMM_II)PF02880(PGM_PMM_III) | 4 | LEU A 368LYS A 367LEU A 381ALA A 348 | None | 0.73A | 1e7cA-1kfiA:undetectable | 1e7cA-1kfiA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1khd | ANTHRANILATEPHOSPHORIBOSYLTRANSFERASE (Pectobacteriumcarotovorum) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N) | 4 | LEU A 249LEU A 213ALA A 216LYS A 220 | None | 0.56A | 1e7cA-1khdA:undetectable | 1e7cA-1khdA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ks8 | ENDO-B-1,4-GLUCANASE (Nasutitermestakasagoensis) |
PF00759(Glyco_hydro_9) | 4 | ALA A 225LEU A 177LEU A 178ALA A 181 | None | 0.81A | 1e7cA-1ks8A:undetectable | 1e7cA-1ks8A:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o3u | CONSERVEDHYPOTHETICAL PROTEINTM0613 (Thermotogamaritima) |
PF05168(HEPN) | 4 | ALA A 109LEU A 8ALA A 11LYS A 12 | None | 0.63A | 1e7cA-1o3uA:undetectable | 1e7cA-1o3uA:13.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ofe | FERREDOXIN-DEPENDENTGLUTAMATE SYNTHASE 2 (Synechocystissp. PCC 6803) |
PF00310(GATase_2)PF01493(GXGXG)PF01645(Glu_synthase)PF04898(Glu_syn_central) | 5 | ALA A 587LEU A 634LEU A 629LEU A 598ALA A 638 | None | 1.36A | 1e7cA-1ofeA:undetectable | 1e7cA-1ofeA:17.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1otk | PHENYLACETIC ACIDDEGRADATION PROTEINPAAC (Escherichiacoli) |
PF05138(PaaA_PaaC) | 4 | ALA A 70LEU A 54LEU A 17ALA A 50 | None | 0.76A | 1e7cA-1otkA:undetectable | 1e7cA-1otkA:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p88 | 3-PHOSPHOSHIKIMATE1-CARBOXYVINYLTRANSFERASE (Escherichiacoli) |
PF00275(EPSP_synthase) | 5 | ALA A 138LEU A 106LEU A 153LEU A 133ALA A 103 | None | 1.37A | 1e7cA-1p88A:undetectable | 1e7cA-1p88A:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pww | LETHAL FACTOR (Bacillusanthracis) |
PF07737(ATLF)PF09156(Anthrax-tox_M) | 4 | ALA A 220LEU A 189LEU A 233ALA A 237 | None | 0.77A | 1e7cA-1pwwA:undetectable | 1e7cA-1pwwA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pzx | HYPOTHETICAL PROTEINAPC36103 (Geobacillusstearothermophilus) |
PF02645(DegV) | 4 | LEU A 105LEU A 73ALA A 76LYS A 77 | None | 0.73A | 1e7cA-1pzxA:undetectable | 1e7cA-1pzxA:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q2l | PROTEASE III (Escherichiacoli) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C)PF16187(Peptidase_M16_M) | 4 | LEU A 575LEU A 634ALA A 637LYS A 638 | None | 0.55A | 1e7cA-1q2lA:undetectable | 1e7cA-1q2lA:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qfc | PROTEIN (PURPLE ACIDPHOSPHATASE) (Rattusnorvegicus) |
PF00149(Metallophos) | 5 | ALA A 11LEU A 88LEU A 50LEU A 218ALA A 184 | None | 1.18A | 1e7cA-1qfcA:undetectable | 1e7cA-1qfcA:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r5a | GLUTATHIONETRANSFERASE (Anophelescracens) |
PF00043(GST_C)PF13417(GST_N_3) | 4 | ALA A 160LEU A 103LEU A 99LEU A 71 | None | 0.80A | 1e7cA-1r5aA:3.5 | 1e7cA-1r5aA:17.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rfv | PYRIDOXAL KINASE (Ovis aries) |
PF08543(Phos_pyr_kin) | 4 | ALA A 228LEU A 289ALA A 274LYS A 275 | None | 0.70A | 1e7cA-1rfvA:3.8 | 1e7cA-1rfvA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s68 | RNA LIGASE 2 (Escherichiavirus T4) |
PF09414(RNA_ligase) | 5 | ALA A 194LEU A 152LEU A 153LEU A 164ALA A 32 | None | 1.40A | 1e7cA-1s68A:undetectable | 1e7cA-1s68A:18.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sml | PROTEIN(PENICILLINASE) (Stenotrophomonasmaltophilia) |
PF00753(Lactamase_B) | 5 | ALA A 106LEU A 113LEU A 114LEU A 82ALA A 85 | None | 1.48A | 1e7cA-1smlA:undetectable | 1e7cA-1smlA:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sxj | ACTIVATOR 1 95 KDASUBUNIT (Saccharomycescerevisiae) |
PF00004(AAA)PF08519(RFC1) | 4 | ALA A 363LEU A 453LEU A 351ALA A 349 | None | 0.78A | 1e7cA-1sxjA:undetectable | 1e7cA-1sxjA:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1szi | MANNOSE-6-PHOSPHATERECEPTOR BINDINGPROTEIN 1 (Mus musculus) |
PF03036(Perilipin) | 4 | ALA A 269LEU A 273LEU A 405ALA A 401 | None | 0.81A | 1e7cA-1sziA:2.1 | 1e7cA-1sziA:17.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 5 | ALA A 21LEU A 135LEU A 139ALA A 158LYS A 162 | None | 0.77A | 1e7cA-1tf0A:36.9 | 1e7cA-1tf0A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 5 | ALA A 21LEU A 135LEU A 139LEU A 155ALA A 158 | None | 0.71A | 1e7cA-1tf0A:36.9 | 1e7cA-1tf0A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 5 | ALA A 213LEU A 327LEU A 331ALA A 350LYS A 351 | DKA A1001 ( 4.0A)DKA A1001 (-4.1A)NoneDKA A1002 ( 3.8A)DKA A1002 (-2.6A) | 0.81A | 1e7cA-1tf0A:36.9 | 1e7cA-1tf0A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 5 | ALA A 213LEU A 327LEU A 331LEU A 347ALA A 350 | DKA A1001 ( 4.0A)DKA A1001 (-4.1A)NoneDKA A1002 ( 4.3A)DKA A1002 ( 3.8A) | 0.86A | 1e7cA-1tf0A:36.9 | 1e7cA-1tf0A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 5 | LEU A 135LYS A 136LEU A 139ALA A 158LYS A 162 | None | 1.04A | 1e7cA-1tf0A:36.9 | 1e7cA-1tf0A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u0m | PUTATIVE POLYKETIDESYNTHASE (Streptomycescoelicolor) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 5 | ALA A 25LEU A 183LEU A 182LEU A 39ALA A 38 | None | 1.50A | 1e7cA-1u0mA:undetectable | 1e7cA-1u0mA:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ulv | GLUCODEXTRANASE (Arthrobacterglobiformis) |
PF00723(Glyco_hydro_15)PF09136(Glucodextran_B)PF09137(Glucodextran_N)PF09985(Glucodextran_C) | 4 | ALA A 154LEU A 242ALA A 245LYS A 246 | None | 0.68A | 1e7cA-1ulvA:undetectable | 1e7cA-1ulvA:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ve5 | THREONINE DEAMINASE (Thermusthermophilus) |
PF00291(PALP) | 5 | ALA A 138LEU A 68LEU A 62ALA A 59LYS A 58 | None | 1.17A | 1e7cA-1ve5A:undetectable | 1e7cA-1ve5A:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vma | CELL DIVISIONPROTEIN FTSY (Thermotogamaritima) |
PF00448(SRP54)PF02881(SRP54_N) | 4 | LEU A 227ALA A 230LYS A 231LYS A 234 | None | 0.69A | 1e7cA-1vmaA:1.9 | 1e7cA-1vmaA:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vzo | RIBOSOMAL PROTEIN S6KINASE ALPHA 5 (Homo sapiens) |
PF00069(Pkinase) | 5 | ALA A 120LEU A 83LEU A 127LEU A 32ALA A 86 | None | 1.05A | 1e7cA-1vzoA:undetectable | 1e7cA-1vzoA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wdd | RIBULOSEBISPHOSPHATECARBOXYLASE SMALLCHAIN C (Oryza sativa) |
PF00101(RuBisCO_small) | 5 | ALA S 116LEU S 42LEU S 86ALA S 89LYS S 90 | None | 1.32A | 1e7cA-1wddS:undetectable | 1e7cA-1wddS:12.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wiw | GLUCOSE-6-PHOSPHATEISOMERASE LIKEPROTEIN (Thermusthermophilus) |
PF10432(bact-PGI_C) | 4 | ALA A 218LEU A 220LEU A 234ALA A 230 | None | 0.81A | 1e7cA-1wiwA:undetectable | 1e7cA-1wiwA:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x1e | 2-DEOXY-D-GLUCONATE3-DEHYDROGENASE (Thermusthermophilus) |
PF13561(adh_short_C2) | 4 | ALA A 112LEU A 60LEU A 71ALA A 64 | None | 0.70A | 1e7cA-1x1eA:undetectable | 1e7cA-1x1eA:17.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xe4 | FEMX (Weissellaviridescens) |
PF02388(FemAB) | 4 | ALA A 94LEU A 98LEU A 105ALA A 71 | None | 0.79A | 1e7cA-1xe4A:undetectable | 1e7cA-1xe4A:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z2z | PROBABLE TRNAPSEUDOURIDINESYNTHASE D (Methanosarcinamazei) |
PF01142(TruD) | 4 | ALA A 295LEU A 329LEU A 330ALA A 335 | None | 0.81A | 1e7cA-1z2zA:undetectable | 1e7cA-1z2zA:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zg4 | BETA-LACTAMASE TEM (Escherichiacoli) |
PF13354(Beta-lactamase2) | 4 | ALA A 249LEU A 49LEU A 51LEU A 194 | None | 0.77A | 1e7cA-1zg4A:undetectable | 1e7cA-1zg4A:18.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a35 | HYPOTHETICAL PROTEINPA4017 (Pseudomonasaeruginosa) |
PF08732(HIM1) | 4 | ALA A 147LEU A 192LEU A 208ALA A 188 | None | 0.77A | 1e7cA-2a35A:undetectable | 1e7cA-2a35A:15.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ao9 | PHAGE PROTEIN (Bacillus cereus) |
PF13022(HTH_Tnp_1_2) | 5 | LEU A 101LEU A 98LEU A 114ALA A 111LYS A 110 | None | 1.32A | 1e7cA-2ao9A:undetectable | 1e7cA-2ao9A:14.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bdq | COPPER HOMEOSTASISPROTEIN CUTC (Streptococcusagalactiae) |
PF03932(CutC) | 4 | ALA A 46LEU A 14LEU A 27ALA A 8 | None | 0.77A | 1e7cA-2bdqA:undetectable | 1e7cA-2bdqA:16.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dvl | ACYL-COADEHYDROGENASE (Thermusthermophilus) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | ALA A 132LEU A 123LEU A 225ALA A 228 | NoneFAD A1001 (-4.4A)NoneNone | 0.79A | 1e7cA-2dvlA:undetectable | 1e7cA-2dvlA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2esn | PROBABLETRANSCRIPTIONALREGULATOR (Pseudomonasaeruginosa) |
PF00126(HTH_1)PF03466(LysR_substrate) | 5 | ALA A 250LEU A 247LEU A 248LEU A 238ALA A 241 | None | 1.31A | 1e7cA-2esnA:undetectable | 1e7cA-2esnA:19.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f2a | ASPARTYL/GLUTAMYL-TRNA(ASN/GLN)AMIDOTRANSFERASESUBUNIT B (Staphylococcusaureus) |
PF02637(GatB_Yqey)PF02934(GatB_N) | 4 | ALA B 163LEU B 224LEU B 9ALA B 193 | None | 0.81A | 1e7cA-2f2aB:undetectable | 1e7cA-2f2aB:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2he3 | GLUTATHIONEPEROXIDASE 2 (Homo sapiens) |
PF00255(GSHPx) | 4 | LEU A 185LEU A 186LEU A 61ALA A 30 | None | 0.65A | 1e7cA-2he3A:undetectable | 1e7cA-2he3A:15.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hjs | USG-1 PROTEINHOMOLOG (Pseudomonasaeruginosa) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 5 | ALA A 83LEU A 126LEU A 125LEU A 100ALA A 105 | None | 1.29A | 1e7cA-2hjsA:undetectable | 1e7cA-2hjsA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hrb | CARBONYL REDUCTASE[NADPH] 3 (Homo sapiens) |
PF00106(adh_short) | 4 | ALA A 46LEU A 35LEU A 19ALA A 22 | None | 0.79A | 1e7cA-2hrbA:undetectable | 1e7cA-2hrbA:18.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hvq | HYPOTHETICAL 37.6KDA PROTEIN INGP24-HOC INTERGENICREGION (Escherichiavirus T4) |
PF09414(RNA_ligase) | 5 | ALA A 194LEU A 152LEU A 153LEU A 164ALA A 32 | None | 1.46A | 1e7cA-2hvqA:4.3 | 1e7cA-2hvqA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ioj | HYPOTHETICAL PROTEINAF_1212 (Archaeoglobusfulgidus) |
PF07085(DRTGG) | 5 | ALA A 243LEU A 265LEU A 255LEU A 244ALA A 268 | None | 1.48A | 1e7cA-2iojA:undetectable | 1e7cA-2iojA:11.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j6i | FORMATEDEHYDROGENASE ([Candida]boidinii) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 4 | ALA A 209LEU A 199LEU A 180ALA A 172 | None | 0.75A | 1e7cA-2j6iA:undetectable | 1e7cA-2j6iA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jfd | FATTY ACID SYNTHASE (Homo sapiens) |
PF00698(Acyl_transf_1)PF16197(KAsynt_C_assoc) | 5 | ALA A 426LEU A 423LEU A 424LEU A 438ALA A 471 | None | 1.24A | 1e7cA-2jfdA:undetectable | 1e7cA-2jfdA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jh2 | O-GLCNACASE NAGJ (Clostridiumperfringens) |
PF00963(Cohesin) | 4 | ALA A 16LYS A 133LEU A 111LEU A 26 | None | 0.74A | 1e7cA-2jh2A:undetectable | 1e7cA-2jh2A:13.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ldx | APO-LACTATEDEHYDROGENASE (Mus musculus) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | ALA A 35LEU A 49LEU A 64LYS A 56 | None | 0.74A | 1e7cA-2ldxA:undetectable | 1e7cA-2ldxA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nwq | PROBABLE SHORT-CHAINDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00106(adh_short) | 5 | ALA A 19LEU A 39LEU A 31LEU A 46ALA A 43 | None | 1.40A | 1e7cA-2nwqA:undetectable | 1e7cA-2nwqA:20.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p5i | BH3822 PROTEIN (Bacillushalodurans) |
PF03099(BPL_LplA_LipB) | 4 | ALA A 54LEU A 106LEU A 236ALA A 239 | None | 0.70A | 1e7cA-2p5iA:undetectable | 1e7cA-2p5iA:18.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pcq | PUTATIVEDIHYDRODIPICOLINATESYNTHASE (Thermusthermophilus) |
PF00701(DHDPS) | 4 | ALA A 219LEU A 208LEU A 207LEU A 182 | None | 0.74A | 1e7cA-2pcqA:undetectable | 1e7cA-2pcqA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pi5 | DNA-DIRECTED RNAPOLYMERASE (Escherichiavirus T7) |
PF00940(RNA_pol)PF14700(RPOL_N) | 4 | ALA A 338LEU A 443LEU A 402ALA A 405 | None | 0.74A | 1e7cA-2pi5A:3.8 | 1e7cA-2pi5A:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2po3 | 4-DEHYDRASE (Streptomycesvenezuelae) |
PF01041(DegT_DnrJ_EryC1) | 4 | ALA A1191LEU A1217LEU A1083ALA A1087 | None | 0.80A | 1e7cA-2po3A:undetectable | 1e7cA-2po3A:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ppt | THIOREDOXIN-2 (Rhodobactercapsulatus) |
PF00085(Thioredoxin) | 4 | ALA A 57LEU A 15LEU A 64ALA A 97 | None | 0.74A | 1e7cA-2pptA:undetectable | 1e7cA-2pptA:13.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pqd | 3-PHOSPHOSHIKIMATE1-CARBOXYVINYLTRANSFERASE (Agrobacteriumsp.) |
PF00275(EPSP_synthase) | 4 | ALA A 445LEU A 18LEU A 415ALA A 254 | None | 0.55A | 1e7cA-2pqdA:undetectable | 1e7cA-2pqdA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qir | AMINOGLYCOSIDE6-N-ACETYLTRANSFERASE TYPE IB11 (Salmonellaenterica) |
PF13523(Acetyltransf_8) | 5 | ALA A 80LEU A 129LEU A 15LEU A 122ALA A 125 | None | 1.41A | 1e7cA-2qirA:undetectable | 1e7cA-2qirA:14.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qjg | PUTATIVE ALDOLASEMJ0400 (Methanocaldococcusjannaschii) |
PF01791(DeoC) | 4 | ALA A 150LEU A 148LEU A 134ALA A 138 | None | 0.81A | 1e7cA-2qjgA:undetectable | 1e7cA-2qjgA:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rdy | BH0842 PROTEIN (Bacillushalodurans) |
PF14498(Glyco_hyd_65N_2) | 5 | ALA A 482LEU A 489LEU A 486LEU A 553ALA A 556 | None | 1.02A | 1e7cA-2rdyA:2.0 | 1e7cA-2rdyA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rh3 | PROTEIN VIRC2 (Agrobacteriumtumefaciens) |
PF07181(VirC2) | 4 | ALA A 88LEU A 185LEU A 190ALA A 189 | None | 0.78A | 1e7cA-2rh3A:undetectable | 1e7cA-2rh3A:11.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v8j | PECTATE LYASE (Yersiniaenterocolitica) |
PF06917(Pectate_lyase_2) | 5 | ALA A 388LEU A 305LEU A 308LEU A 329ALA A 304 | None | 1.36A | 1e7cA-2v8jA:2.9 | 1e7cA-2v8jA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vz9 | FATTY ACID SYNTHASE (Sus scrofa) |
PF00107(ADH_zinc_N)PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF08242(Methyltransf_12)PF08659(KR)PF14765(PS-DH)PF16197(KAsynt_C_assoc) | 5 | ALA A 426LEU A 423LEU A 424LEU A 438ALA A 471 | None | 1.14A | 1e7cA-2vz9A:undetectable | 1e7cA-2vz9A:12.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x4g | NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE (Pseudomonasaeruginosa) |
PF01370(Epimerase) | 5 | ALA A 228LEU A 239LEU A 240LEU A 314ALA A 310 | None | 1.28A | 1e7cA-2x4gA:undetectable | 1e7cA-2x4gA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xfg | ENDOGLUCANASE 1 (Ruminiclostridiumthermocellum) |
PF00759(Glyco_hydro_9) | 4 | ALA A 226LEU A 180ALA A 183LYS A 184 | None | 0.52A | 1e7cA-2xfgA:0.8 | 1e7cA-2xfgA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xgo | XCOGT (Xanthomonascampestris) |
PF13432(TPR_16)PF13844(Glyco_transf_41) | 4 | LEU A 303LEU A 272ALA A 275LYS A 276 | None | 0.81A | 1e7cA-2xgoA:undetectable | 1e7cA-2xgoA:23.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xsj | SULFITE REDUCTASEBETA SUBUNIT (Desulfomicrobiumnorvegicum) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr)PF12838(Fer4_7) | 4 | LEU B 108ALA B 111LYS B 112LYS B 115 | None | 0.42A | 1e7cA-2xsjB:undetectable | 1e7cA-2xsjB:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yik | ENDOGLUCANASE (Ruminiclostridiumthermocellum) |
PF00759(Glyco_hydro_9) | 4 | ALA A 292LEU A 245ALA A 248LYS A 249 | None | 0.58A | 1e7cA-2yikA:0.8 | 1e7cA-2yikA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zbl | PUTATIVE ISOMERASE (Salmonellaenterica) |
PF07221(GlcNAc_2-epim) | 4 | LEU A 257LEU A 275ALA A 278LYS A 279 | None | 0.80A | 1e7cA-2zblA:undetectable | 1e7cA-2zblA:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a5v | ALPHA-GALACTOSIDASE (Umbelopsisvinacea) |
PF16499(Melibiase_2) | 4 | LEU A 88LEU A 29ALA A 32LYS A 33 | None | 0.69A | 1e7cA-3a5vA:undetectable | 1e7cA-3a5vA:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b1f | PUTATIVE PREPHENATEDEHYDROGENASE (Streptococcusmutans) |
PF02153(PDH) | 4 | ALA A 136LEU A 11LEU A 20ALA A 19 | None | 0.80A | 1e7cA-3b1fA:undetectable | 1e7cA-3b1fA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b2y | METALLOPEPTIDASECONTAININGCO-CATALYTICMETALLOACTIVE SITE (Shewanelladenitrificans) |
PF04952(AstE_AspA) | 4 | ALA A 262LEU A 195LEU A 166ALA A 242 | None | 0.79A | 1e7cA-3b2yA:undetectable | 1e7cA-3b2yA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c1x | HEPATOCYTE GROWTHFACTOR RECEPTOR (Homo sapiens) |
PF07714(Pkinase_Tyr) | 4 | LEU A1186ALA A1189LYS A1190LYS A1193 | None | 0.40A | 1e7cA-3c1xA:undetectable | 1e7cA-3c1xA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c7j | TRANSCRIPTIONALREGULATOR, GNTRFAMILY (Pseudomonassyringae groupgenomosp. 3) |
PF00392(GntR)PF07729(FCD) | 4 | ALA A 124LEU A 151LEU A 196ALA A 199 | None | 0.50A | 1e7cA-3c7jA:2.2 | 1e7cA-3c7jA:18.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cea | MYO-INOSITOL2-DEHYDROGENASE (Lactobacillusplantarum) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | ALA A 38LEU A 53LEU A 35ALA A 23 | None | 0.80A | 1e7cA-3ceaA:undetectable | 1e7cA-3ceaA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cyj | MANDELATERACEMASE/MUCONATELACTONIZINGENZYME-LIKE PROTEIN (Rubrobacterxylanophilus) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ALA A 106LEU A 64LEU A 9LEU A 107ALA A 68 | None | 1.48A | 1e7cA-3cyjA:undetectable | 1e7cA-3cyjA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d8x | THIOREDOXINREDUCTASE 1 (Saccharomycescerevisiae) |
PF07992(Pyr_redox_2) | 4 | ALA A 213LEU A 183LEU A 226ALA A 158 | None | 0.67A | 1e7cA-3d8xA:undetectable | 1e7cA-3d8xA:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dbi | SUGAR-BINDINGTRANSCRIPTIONALREGULATOR, LACIFAMILY (Escherichiacoli) |
PF13377(Peripla_BP_3) | 4 | ALA A 122LEU A 66LEU A 64LEU A 308 | None | 0.78A | 1e7cA-3dbiA:undetectable | 1e7cA-3dbiA:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dh4 | SODIUM/GLUCOSECOTRANSPORTER (Vibrioparahaemolyticus) |
PF00474(SSF) | 4 | ALA A 170LEU A 147LEU A 407ALA A 410 | None | 0.76A | 1e7cA-3dh4A:2.8 | 1e7cA-3dh4A:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dm0 | MALTOSE-BINDINGPERIPLASMIC PROTEINFUSED WITH RACK1 (Arabidopsisthaliana;Escherichiacoli) |
PF00400(WD40)PF01547(SBP_bac_1) | 5 | ALA A1252LEU A1232LEU A1250LEU A1241ALA A1210 | None | 1.47A | 1e7cA-3dm0A:undetectable | 1e7cA-3dm0A:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eaf | ABC TRANSPORTER,SUBSTRATE BINDINGPROTEIN (Aeropyrumpernix) |
PF13458(Peripla_BP_6) | 5 | ALA A 120LEU A 340LEU A 341LEU A 361ALA A 344 | None | 1.39A | 1e7cA-3eafA:undetectable | 1e7cA-3eafA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ebv | CHINITASE A (Streptomycescoelicolor) |
PF00704(Glyco_hydro_18) | 4 | ALA A 206LEU A 221LEU A 247ALA A 243 | None | 0.75A | 1e7cA-3ebvA:undetectable | 1e7cA-3ebvA:17.82 |