SIMILAR PATTERNS OF AMINO ACIDS FOR 1E7C_A_HLTA4008

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aql BILE-SALT ACTIVATED
LIPASE


(Bos taurus)
PF00135
(COesterase)
4 LEU A 258
LEU A 234
ALA A 237
LYS A 238
None
0.68A 1e7cA-1aqlA:
0.0
1e7cA-1aqlA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1atj PEROXIDASE C1A

(Armoracia
rusticana)
PF00141
(peroxidase)
4 ALA A  51
LEU A 100
LEU A 101
LYS A  84
None
0.80A 1e7cA-1atjA:
0.7
1e7cA-1atjA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bkh MUCONATE LACTONIZING
ENZYME


(Pseudomonas
putida)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
5 ALA A 193
LYS A 186
LEU A 189
LEU A 158
ALA A 154
None
1.38A 1e7cA-1bkhA:
0.0
1e7cA-1bkhA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c8x ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE H


(Streptomyces
plicatus)
PF00704
(Glyco_hydro_18)
4 ALA A  46
LEU A  59
LEU A  88
ALA A 118
ALA  A  46 ( 0.0A)
LEU  A  59 ( 0.6A)
LEU  A  88 ( 0.5A)
ALA  A 118 ( 0.0A)
0.79A 1e7cA-1c8xA:
0.0
1e7cA-1c8xA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cwu ENOYL ACP REDUCTASE

(Brassica napus)
PF13561
(adh_short_C2)
4 ALA A  24
LEU A 137
LEU A 169
ALA A  90
None
NAD  A 501 (-3.9A)
None
NAD  A 501 (-3.9A)
0.80A 1e7cA-1cwuA:
undetectable
1e7cA-1cwuA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1db3 GDP-MANNOSE
4,6-DEHYDRATASE


(Escherichia
coli)
PF16363
(GDP_Man_Dehyd)
4 LEU A 211
LEU A 350
ALA A 353
LYS A 354
None
0.75A 1e7cA-1db3A:
undetectable
1e7cA-1db3A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6w SHORT CHAIN
3-HYDROXYACYL-COA
DEHYDROGENASE


(Rattus
norvegicus)
PF00106
(adh_short)
4 LEU A  39
LEU A  24
ALA A  27
LYS A  28
None
0.70A 1e7cA-1e6wA:
0.0
1e7cA-1e6wA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g4u PROTEIN TYROSINE
PHOSPHATASE SPTP


(Salmonella
enterica)
PF00102
(Y_phosphatase)
PF03545
(YopE)
5 LEU S 183
LEU S 186
ALA S 277
LYS S 278
LYS S 281
None
1.39A 1e7cA-1g4uS:
2.7
1e7cA-1g4uS:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT


(Rhodobacter
capsulatus)
PF01078
(Mg_chelatase)
4 ALA A 272
LEU A 315
LEU A 295
ALA A 298
None
0.73A 1e7cA-1g8pA:
0.0
1e7cA-1g8pA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gk2 HISTIDINE
AMMONIA-LYASE


(Pseudomonas
putida)
PF00221
(Lyase_aromatic)
4 ALA A 204
LEU A 341
LEU A 303
ALA A 299
None
0.80A 1e7cA-1gk2A:
2.1
1e7cA-1gk2A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gwc GLUTATHIONE
S-TRANSFERASE TSI-1


(Aegilops
tauschii)
PF00043
(GST_C)
PF02798
(GST_N)
5 ALA A 177
LEU A 215
LEU A 216
LEU A 178
ALA A 219
None
1.26A 1e7cA-1gwcA:
3.6
1e7cA-1gwcA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gwc GLUTATHIONE
S-TRANSFERASE TSI-1


(Aegilops
tauschii)
PF00043
(GST_C)
PF02798
(GST_N)
4 ALA A 177
LEU A 216
ALA A 219
LYS A 220
None
0.75A 1e7cA-1gwcA:
3.6
1e7cA-1gwcA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hrd GLUTAMATE
DEHYDROGENASE


([Clostridium]
symbiosum)
PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N)
5 ALA A 245
LEU A 259
LEU A 235
LEU A 249
ALA A 256
None
1.44A 1e7cA-1hrdA:
undetectable
1e7cA-1hrdA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i2o TRANSALDOLASE B

(Escherichia
coli)
PF00923
(TAL_FSA)
4 ALA A 112
LEU A 133
LEU A 146
ALA A 142
None
0.80A 1e7cA-1i2oA:
undetectable
1e7cA-1i2oA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ia7 CELLULASE CEL9M

([Clostridium]
cellulolyticum)
PF00759
(Glyco_hydro_9)
4 ALA A 223
LEU A 181
ALA A 184
LYS A 185
None
0.66A 1e7cA-1ia7A:
0.9
1e7cA-1ia7A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1igw ISOCITRATE LYASE

(Escherichia
coli)
PF00463
(ICL)
4 ALA A 131
LEU A  78
ALA A  81
LYS A  82
None
0.77A 1e7cA-1igwA:
undetectable
1e7cA-1igwA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iho PANTOATE--BETA-ALANI
NE LIGASE


(Escherichia
coli)
PF02569
(Pantoate_ligase)
5 ALA A 272
LEU A 204
LEU A 269
LEU A 193
ALA A 201
None
1.39A 1e7cA-1ihoA:
undetectable
1e7cA-1ihoA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iw8 ACID PHOSPHATASE

(Shimwellia
blattae)
PF01569
(PAP2)
5 LEU A  95
LEU A  98
LEU A 218
ALA A 221
LYS A 222
None
1.18A 1e7cA-1iw8A:
undetectable
1e7cA-1iw8A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jmy BILE-SALT-ACTIVATED
LIPASE


(Homo sapiens)
PF00135
(COesterase)
5 ALA A 251
LEU A 258
LEU A 234
ALA A 237
LYS A 238
None
1.18A 1e7cA-1jmyA:
undetectable
1e7cA-1jmyA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k1c CATABOLITE
REPRESSION HPR-LIKE
PROTEIN


(Bacillus
subtilis)
PF00381
(PTS-HPr)
4 ALA A  73
LEU A  63
ALA A  44
LYS A  45
None
0.78A 1e7cA-1k1cA:
undetectable
1e7cA-1k1cA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfi PHOSPHOGLUCOMUTASE 1

(Paramecium
tetraurelia)
PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III)
4 LEU A 368
LYS A 367
LEU A 381
ALA A 348
None
0.73A 1e7cA-1kfiA:
undetectable
1e7cA-1kfiA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE


(Pectobacterium
carotovorum)
PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
4 LEU A 249
LEU A 213
ALA A 216
LYS A 220
None
0.56A 1e7cA-1khdA:
undetectable
1e7cA-1khdA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ks8 ENDO-B-1,4-GLUCANASE

(Nasutitermes
takasagoensis)
PF00759
(Glyco_hydro_9)
4 ALA A 225
LEU A 177
LEU A 178
ALA A 181
None
0.81A 1e7cA-1ks8A:
undetectable
1e7cA-1ks8A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o3u CONSERVED
HYPOTHETICAL PROTEIN
TM0613


(Thermotoga
maritima)
PF05168
(HEPN)
4 ALA A 109
LEU A   8
ALA A  11
LYS A  12
None
0.63A 1e7cA-1o3uA:
undetectable
1e7cA-1o3uA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ofe FERREDOXIN-DEPENDENT
GLUTAMATE SYNTHASE 2


(Synechocystis
sp. PCC 6803)
PF00310
(GATase_2)
PF01493
(GXGXG)
PF01645
(Glu_synthase)
PF04898
(Glu_syn_central)
5 ALA A 587
LEU A 634
LEU A 629
LEU A 598
ALA A 638
None
1.36A 1e7cA-1ofeA:
undetectable
1e7cA-1ofeA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1otk PHENYLACETIC ACID
DEGRADATION PROTEIN
PAAC


(Escherichia
coli)
PF05138
(PaaA_PaaC)
4 ALA A  70
LEU A  54
LEU A  17
ALA A  50
None
0.76A 1e7cA-1otkA:
undetectable
1e7cA-1otkA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p88 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE


(Escherichia
coli)
PF00275
(EPSP_synthase)
5 ALA A 138
LEU A 106
LEU A 153
LEU A 133
ALA A 103
None
1.37A 1e7cA-1p88A:
undetectable
1e7cA-1p88A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pww LETHAL FACTOR

(Bacillus
anthracis)
PF07737
(ATLF)
PF09156
(Anthrax-tox_M)
4 ALA A 220
LEU A 189
LEU A 233
ALA A 237
None
0.77A 1e7cA-1pwwA:
undetectable
1e7cA-1pwwA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pzx HYPOTHETICAL PROTEIN
APC36103


(Geobacillus
stearothermophilus)
PF02645
(DegV)
4 LEU A 105
LEU A  73
ALA A  76
LYS A  77
None
0.73A 1e7cA-1pzxA:
undetectable
1e7cA-1pzxA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q2l PROTEASE III

(Escherichia
coli)
PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF16187
(Peptidase_M16_M)
4 LEU A 575
LEU A 634
ALA A 637
LYS A 638
None
0.55A 1e7cA-1q2lA:
undetectable
1e7cA-1q2lA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qfc PROTEIN (PURPLE ACID
PHOSPHATASE)


(Rattus
norvegicus)
PF00149
(Metallophos)
5 ALA A  11
LEU A  88
LEU A  50
LEU A 218
ALA A 184
None
1.18A 1e7cA-1qfcA:
undetectable
1e7cA-1qfcA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r5a GLUTATHIONE
TRANSFERASE


(Anopheles
cracens)
PF00043
(GST_C)
PF13417
(GST_N_3)
4 ALA A 160
LEU A 103
LEU A  99
LEU A  71
None
0.80A 1e7cA-1r5aA:
3.5
1e7cA-1r5aA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rfv PYRIDOXAL KINASE

(Ovis aries)
PF08543
(Phos_pyr_kin)
4 ALA A 228
LEU A 289
ALA A 274
LYS A 275
None
0.70A 1e7cA-1rfvA:
3.8
1e7cA-1rfvA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s68 RNA LIGASE 2

(Escherichia
virus T4)
PF09414
(RNA_ligase)
5 ALA A 194
LEU A 152
LEU A 153
LEU A 164
ALA A  32
None
1.40A 1e7cA-1s68A:
undetectable
1e7cA-1s68A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sml PROTEIN
(PENICILLINASE)


(Stenotrophomonas
maltophilia)
PF00753
(Lactamase_B)
5 ALA A 106
LEU A 113
LEU A 114
LEU A  82
ALA A  85
None
1.48A 1e7cA-1smlA:
undetectable
1e7cA-1smlA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sxj ACTIVATOR 1 95 KDA
SUBUNIT


(Saccharomyces
cerevisiae)
PF00004
(AAA)
PF08519
(RFC1)
4 ALA A 363
LEU A 453
LEU A 351
ALA A 349
None
0.78A 1e7cA-1sxjA:
undetectable
1e7cA-1sxjA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1szi MANNOSE-6-PHOSPHATE
RECEPTOR BINDING
PROTEIN 1


(Mus musculus)
PF03036
(Perilipin)
4 ALA A 269
LEU A 273
LEU A 405
ALA A 401
None
0.81A 1e7cA-1sziA:
2.1
1e7cA-1sziA:
17.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens)
PF00273
(Serum_albumin)
5 ALA A  21
LEU A 135
LEU A 139
ALA A 158
LYS A 162
None
0.77A 1e7cA-1tf0A:
36.9
1e7cA-1tf0A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens)
PF00273
(Serum_albumin)
5 ALA A  21
LEU A 135
LEU A 139
LEU A 155
ALA A 158
None
0.71A 1e7cA-1tf0A:
36.9
1e7cA-1tf0A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens)
PF00273
(Serum_albumin)
5 ALA A 213
LEU A 327
LEU A 331
ALA A 350
LYS A 351
DKA  A1001 ( 4.0A)
DKA  A1001 (-4.1A)
None
DKA  A1002 ( 3.8A)
DKA  A1002 (-2.6A)
0.81A 1e7cA-1tf0A:
36.9
1e7cA-1tf0A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens)
PF00273
(Serum_albumin)
5 ALA A 213
LEU A 327
LEU A 331
LEU A 347
ALA A 350
DKA  A1001 ( 4.0A)
DKA  A1001 (-4.1A)
None
DKA  A1002 ( 4.3A)
DKA  A1002 ( 3.8A)
0.86A 1e7cA-1tf0A:
36.9
1e7cA-1tf0A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens)
PF00273
(Serum_albumin)
5 LEU A 135
LYS A 136
LEU A 139
ALA A 158
LYS A 162
None
1.04A 1e7cA-1tf0A:
36.9
1e7cA-1tf0A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u0m PUTATIVE POLYKETIDE
SYNTHASE


(Streptomyces
coelicolor)
PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C)
5 ALA A  25
LEU A 183
LEU A 182
LEU A  39
ALA A  38
None
1.50A 1e7cA-1u0mA:
undetectable
1e7cA-1u0mA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ulv GLUCODEXTRANASE

(Arthrobacter
globiformis)
PF00723
(Glyco_hydro_15)
PF09136
(Glucodextran_B)
PF09137
(Glucodextran_N)
PF09985
(Glucodextran_C)
4 ALA A 154
LEU A 242
ALA A 245
LYS A 246
None
0.68A 1e7cA-1ulvA:
undetectable
1e7cA-1ulvA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ve5 THREONINE DEAMINASE

(Thermus
thermophilus)
PF00291
(PALP)
5 ALA A 138
LEU A  68
LEU A  62
ALA A  59
LYS A  58
None
1.17A 1e7cA-1ve5A:
undetectable
1e7cA-1ve5A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vma CELL DIVISION
PROTEIN FTSY


(Thermotoga
maritima)
PF00448
(SRP54)
PF02881
(SRP54_N)
4 LEU A 227
ALA A 230
LYS A 231
LYS A 234
None
0.69A 1e7cA-1vmaA:
1.9
1e7cA-1vmaA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vzo RIBOSOMAL PROTEIN S6
KINASE ALPHA 5


(Homo sapiens)
PF00069
(Pkinase)
5 ALA A 120
LEU A  83
LEU A 127
LEU A  32
ALA A  86
None
1.05A 1e7cA-1vzoA:
undetectable
1e7cA-1vzoA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wdd RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN C


(Oryza sativa)
PF00101
(RuBisCO_small)
5 ALA S 116
LEU S  42
LEU S  86
ALA S  89
LYS S  90
None
1.32A 1e7cA-1wddS:
undetectable
1e7cA-1wddS:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wiw GLUCOSE-6-PHOSPHATE
ISOMERASE LIKE
PROTEIN


(Thermus
thermophilus)
PF10432
(bact-PGI_C)
4 ALA A 218
LEU A 220
LEU A 234
ALA A 230
None
0.81A 1e7cA-1wiwA:
undetectable
1e7cA-1wiwA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x1e 2-DEOXY-D-GLUCONATE
3-DEHYDROGENASE


(Thermus
thermophilus)
PF13561
(adh_short_C2)
4 ALA A 112
LEU A  60
LEU A  71
ALA A  64
None
0.70A 1e7cA-1x1eA:
undetectable
1e7cA-1x1eA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xe4 FEMX

(Weissella
viridescens)
PF02388
(FemAB)
4 ALA A  94
LEU A  98
LEU A 105
ALA A  71
None
0.79A 1e7cA-1xe4A:
undetectable
1e7cA-1xe4A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z2z PROBABLE TRNA
PSEUDOURIDINE
SYNTHASE D


(Methanosarcina
mazei)
PF01142
(TruD)
4 ALA A 295
LEU A 329
LEU A 330
ALA A 335
None
0.81A 1e7cA-1z2zA:
undetectable
1e7cA-1z2zA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zg4 BETA-LACTAMASE TEM

(Escherichia
coli)
PF13354
(Beta-lactamase2)
4 ALA A 249
LEU A  49
LEU A  51
LEU A 194
None
0.77A 1e7cA-1zg4A:
undetectable
1e7cA-1zg4A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a35 HYPOTHETICAL PROTEIN
PA4017


(Pseudomonas
aeruginosa)
PF08732
(HIM1)
4 ALA A 147
LEU A 192
LEU A 208
ALA A 188
None
0.77A 1e7cA-2a35A:
undetectable
1e7cA-2a35A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ao9 PHAGE PROTEIN

(Bacillus cereus)
PF13022
(HTH_Tnp_1_2)
5 LEU A 101
LEU A  98
LEU A 114
ALA A 111
LYS A 110
None
1.32A 1e7cA-2ao9A:
undetectable
1e7cA-2ao9A:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bdq COPPER HOMEOSTASIS
PROTEIN CUTC


(Streptococcus
agalactiae)
PF03932
(CutC)
4 ALA A  46
LEU A  14
LEU A  27
ALA A   8
None
0.77A 1e7cA-2bdqA:
undetectable
1e7cA-2bdqA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dvl ACYL-COA
DEHYDROGENASE


(Thermus
thermophilus)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
4 ALA A 132
LEU A 123
LEU A 225
ALA A 228
None
FAD  A1001 (-4.4A)
None
None
0.79A 1e7cA-2dvlA:
undetectable
1e7cA-2dvlA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2esn PROBABLE
TRANSCRIPTIONAL
REGULATOR


(Pseudomonas
aeruginosa)
PF00126
(HTH_1)
PF03466
(LysR_substrate)
5 ALA A 250
LEU A 247
LEU A 248
LEU A 238
ALA A 241
None
1.31A 1e7cA-2esnA:
undetectable
1e7cA-2esnA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f2a ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B


(Staphylococcus
aureus)
PF02637
(GatB_Yqey)
PF02934
(GatB_N)
4 ALA B 163
LEU B 224
LEU B   9
ALA B 193
None
0.81A 1e7cA-2f2aB:
undetectable
1e7cA-2f2aB:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2he3 GLUTATHIONE
PEROXIDASE 2


(Homo sapiens)
PF00255
(GSHPx)
4 LEU A 185
LEU A 186
LEU A  61
ALA A  30
None
0.65A 1e7cA-2he3A:
undetectable
1e7cA-2he3A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hjs USG-1 PROTEIN
HOMOLOG


(Pseudomonas
aeruginosa)
PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC)
5 ALA A  83
LEU A 126
LEU A 125
LEU A 100
ALA A 105
None
1.29A 1e7cA-2hjsA:
undetectable
1e7cA-2hjsA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hrb CARBONYL REDUCTASE
[NADPH] 3


(Homo sapiens)
PF00106
(adh_short)
4 ALA A  46
LEU A  35
LEU A  19
ALA A  22
None
0.79A 1e7cA-2hrbA:
undetectable
1e7cA-2hrbA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION


(Escherichia
virus T4)
PF09414
(RNA_ligase)
5 ALA A 194
LEU A 152
LEU A 153
LEU A 164
ALA A  32
None
1.46A 1e7cA-2hvqA:
4.3
1e7cA-2hvqA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ioj HYPOTHETICAL PROTEIN
AF_1212


(Archaeoglobus
fulgidus)
PF07085
(DRTGG)
5 ALA A 243
LEU A 265
LEU A 255
LEU A 244
ALA A 268
None
1.48A 1e7cA-2iojA:
undetectable
1e7cA-2iojA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j6i FORMATE
DEHYDROGENASE


([Candida]
boidinii)
PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
4 ALA A 209
LEU A 199
LEU A 180
ALA A 172
None
0.75A 1e7cA-2j6iA:
undetectable
1e7cA-2j6iA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jfd FATTY ACID SYNTHASE

(Homo sapiens)
PF00698
(Acyl_transf_1)
PF16197
(KAsynt_C_assoc)
5 ALA A 426
LEU A 423
LEU A 424
LEU A 438
ALA A 471
None
1.24A 1e7cA-2jfdA:
undetectable
1e7cA-2jfdA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jh2 O-GLCNACASE NAGJ

(Clostridium
perfringens)
PF00963
(Cohesin)
4 ALA A  16
LYS A 133
LEU A 111
LEU A  26
None
0.74A 1e7cA-2jh2A:
undetectable
1e7cA-2jh2A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ldx APO-LACTATE
DEHYDROGENASE


(Mus musculus)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 ALA A  35
LEU A  49
LEU A  64
LYS A  56
None
0.74A 1e7cA-2ldxA:
undetectable
1e7cA-2ldxA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nwq PROBABLE SHORT-CHAIN
DEHYDROGENASE


(Pseudomonas
aeruginosa)
PF00106
(adh_short)
5 ALA A  19
LEU A  39
LEU A  31
LEU A  46
ALA A  43
None
1.40A 1e7cA-2nwqA:
undetectable
1e7cA-2nwqA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p5i BH3822 PROTEIN

(Bacillus
halodurans)
PF03099
(BPL_LplA_LipB)
4 ALA A  54
LEU A 106
LEU A 236
ALA A 239
None
0.70A 1e7cA-2p5iA:
undetectable
1e7cA-2p5iA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pcq PUTATIVE
DIHYDRODIPICOLINATE
SYNTHASE


(Thermus
thermophilus)
PF00701
(DHDPS)
4 ALA A 219
LEU A 208
LEU A 207
LEU A 182
None
0.74A 1e7cA-2pcqA:
undetectable
1e7cA-2pcqA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pi5 DNA-DIRECTED RNA
POLYMERASE


(Escherichia
virus T7)
PF00940
(RNA_pol)
PF14700
(RPOL_N)
4 ALA A 338
LEU A 443
LEU A 402
ALA A 405
None
0.74A 1e7cA-2pi5A:
3.8
1e7cA-2pi5A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2po3 4-DEHYDRASE

(Streptomyces
venezuelae)
PF01041
(DegT_DnrJ_EryC1)
4 ALA A1191
LEU A1217
LEU A1083
ALA A1087
None
0.80A 1e7cA-2po3A:
undetectable
1e7cA-2po3A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ppt THIOREDOXIN-2

(Rhodobacter
capsulatus)
PF00085
(Thioredoxin)
4 ALA A  57
LEU A  15
LEU A  64
ALA A  97
None
0.74A 1e7cA-2pptA:
undetectable
1e7cA-2pptA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE


(Agrobacterium
sp.)
PF00275
(EPSP_synthase)
4 ALA A 445
LEU A  18
LEU A 415
ALA A 254
None
0.55A 1e7cA-2pqdA:
undetectable
1e7cA-2pqdA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qir AMINOGLYCOSIDE
6-N-ACETYLTRANSFERAS
E TYPE IB11


(Salmonella
enterica)
PF13523
(Acetyltransf_8)
5 ALA A  80
LEU A 129
LEU A  15
LEU A 122
ALA A 125
None
1.41A 1e7cA-2qirA:
undetectable
1e7cA-2qirA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qjg PUTATIVE ALDOLASE
MJ0400


(Methanocaldococcus
jannaschii)
PF01791
(DeoC)
4 ALA A 150
LEU A 148
LEU A 134
ALA A 138
None
0.81A 1e7cA-2qjgA:
undetectable
1e7cA-2qjgA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rdy BH0842 PROTEIN

(Bacillus
halodurans)
PF14498
(Glyco_hyd_65N_2)
5 ALA A 482
LEU A 489
LEU A 486
LEU A 553
ALA A 556
None
1.02A 1e7cA-2rdyA:
2.0
1e7cA-2rdyA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rh3 PROTEIN VIRC2

(Agrobacterium
tumefaciens)
PF07181
(VirC2)
4 ALA A  88
LEU A 185
LEU A 190
ALA A 189
None
0.78A 1e7cA-2rh3A:
undetectable
1e7cA-2rh3A:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v8j PECTATE LYASE

(Yersinia
enterocolitica)
PF06917
(Pectate_lyase_2)
5 ALA A 388
LEU A 305
LEU A 308
LEU A 329
ALA A 304
None
1.36A 1e7cA-2v8jA:
2.9
1e7cA-2v8jA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vz9 FATTY ACID SYNTHASE

(Sus scrofa)
PF00107
(ADH_zinc_N)
PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF08242
(Methyltransf_12)
PF08659
(KR)
PF14765
(PS-DH)
PF16197
(KAsynt_C_assoc)
5 ALA A 426
LEU A 423
LEU A 424
LEU A 438
ALA A 471
None
1.14A 1e7cA-2vz9A:
undetectable
1e7cA-2vz9A:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x4g NUCLEOSIDE-DIPHOSPHA
TE-SUGAR EPIMERASE


(Pseudomonas
aeruginosa)
PF01370
(Epimerase)
5 ALA A 228
LEU A 239
LEU A 240
LEU A 314
ALA A 310
None
1.28A 1e7cA-2x4gA:
undetectable
1e7cA-2x4gA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xfg ENDOGLUCANASE 1

(Ruminiclostridium
thermocellum)
PF00759
(Glyco_hydro_9)
4 ALA A 226
LEU A 180
ALA A 183
LYS A 184
None
0.52A 1e7cA-2xfgA:
0.8
1e7cA-2xfgA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xgo XCOGT

(Xanthomonas
campestris)
PF13432
(TPR_16)
PF13844
(Glyco_transf_41)
4 LEU A 303
LEU A 272
ALA A 275
LYS A 276
None
0.81A 1e7cA-2xgoA:
undetectable
1e7cA-2xgoA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xsj SULFITE REDUCTASE
BETA SUBUNIT


(Desulfomicrobium
norvegicum)
PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr)
PF12838
(Fer4_7)
4 LEU B 108
ALA B 111
LYS B 112
LYS B 115
None
0.42A 1e7cA-2xsjB:
undetectable
1e7cA-2xsjB:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yik ENDOGLUCANASE

(Ruminiclostridium
thermocellum)
PF00759
(Glyco_hydro_9)
4 ALA A 292
LEU A 245
ALA A 248
LYS A 249
None
0.58A 1e7cA-2yikA:
0.8
1e7cA-2yikA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbl PUTATIVE ISOMERASE

(Salmonella
enterica)
PF07221
(GlcNAc_2-epim)
4 LEU A 257
LEU A 275
ALA A 278
LYS A 279
None
0.80A 1e7cA-2zblA:
undetectable
1e7cA-2zblA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a5v ALPHA-GALACTOSIDASE

(Umbelopsis
vinacea)
PF16499
(Melibiase_2)
4 LEU A  88
LEU A  29
ALA A  32
LYS A  33
None
0.69A 1e7cA-3a5vA:
undetectable
1e7cA-3a5vA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b1f PUTATIVE PREPHENATE
DEHYDROGENASE


(Streptococcus
mutans)
PF02153
(PDH)
4 ALA A 136
LEU A  11
LEU A  20
ALA A  19
None
0.80A 1e7cA-3b1fA:
undetectable
1e7cA-3b1fA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE


(Shewanella
denitrificans)
PF04952
(AstE_AspA)
4 ALA A 262
LEU A 195
LEU A 166
ALA A 242
None
0.79A 1e7cA-3b2yA:
undetectable
1e7cA-3b2yA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c1x HEPATOCYTE GROWTH
FACTOR RECEPTOR


(Homo sapiens)
PF07714
(Pkinase_Tyr)
4 LEU A1186
ALA A1189
LYS A1190
LYS A1193
None
0.40A 1e7cA-3c1xA:
undetectable
1e7cA-3c1xA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c7j TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY


(Pseudomonas
syringae group
genomosp. 3)
PF00392
(GntR)
PF07729
(FCD)
4 ALA A 124
LEU A 151
LEU A 196
ALA A 199
None
0.50A 1e7cA-3c7jA:
2.2
1e7cA-3c7jA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cea MYO-INOSITOL
2-DEHYDROGENASE


(Lactobacillus
plantarum)
PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C)
4 ALA A  38
LEU A  53
LEU A  35
ALA A  23
None
0.80A 1e7cA-3ceaA:
undetectable
1e7cA-3ceaA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cyj MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN


(Rubrobacter
xylanophilus)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
5 ALA A 106
LEU A  64
LEU A   9
LEU A 107
ALA A  68
None
1.48A 1e7cA-3cyjA:
undetectable
1e7cA-3cyjA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d8x THIOREDOXIN
REDUCTASE 1


(Saccharomyces
cerevisiae)
PF07992
(Pyr_redox_2)
4 ALA A 213
LEU A 183
LEU A 226
ALA A 158
None
0.67A 1e7cA-3d8xA:
undetectable
1e7cA-3d8xA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dbi SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY


(Escherichia
coli)
PF13377
(Peripla_BP_3)
4 ALA A 122
LEU A  66
LEU A  64
LEU A 308
None
0.78A 1e7cA-3dbiA:
undetectable
1e7cA-3dbiA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dh4 SODIUM/GLUCOSE
COTRANSPORTER


(Vibrio
parahaemolyticus)
PF00474
(SSF)
4 ALA A 170
LEU A 147
LEU A 407
ALA A 410
None
0.76A 1e7cA-3dh4A:
2.8
1e7cA-3dh4A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dm0 MALTOSE-BINDING
PERIPLASMIC PROTEIN
FUSED WITH RACK1


(Arabidopsis
thaliana;
Escherichia
coli)
PF00400
(WD40)
PF01547
(SBP_bac_1)
5 ALA A1252
LEU A1232
LEU A1250
LEU A1241
ALA A1210
None
1.47A 1e7cA-3dm0A:
undetectable
1e7cA-3dm0A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eaf ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN


(Aeropyrum
pernix)
PF13458
(Peripla_BP_6)
5 ALA A 120
LEU A 340
LEU A 341
LEU A 361
ALA A 344
None
1.39A 1e7cA-3eafA:
undetectable
1e7cA-3eafA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ebv CHINITASE A

(Streptomyces
coelicolor)
PF00704
(Glyco_hydro_18)
4 ALA A 206
LEU A 221
LEU A 247
ALA A 243
None
0.75A 1e7cA-3ebvA:
undetectable
1e7cA-3ebvA:
17.82