SIMILAR PATTERNS OF AMINO ACIDS FOR 1E7B_A_HLTA4001
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 13pk | 3-PHOSPHOGLYCERATEKINASE (Trypanosomabrucei) |
PF00162(PGK) | 4 | LYS A 219ALA A 218ASP A 377GLY A 339 | 3PG A 423 ( 2.6A)ADP A 421 (-3.4A) MG A 422 ( 3.4A)ADP A 421 ( 4.1A) | 0.97A | 1e7bA-13pkA:0.0 | 1e7bA-13pkA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bt2 | PROTEIN (CATECHOLOXIDASE) (Ipomoea batatas) |
PF00264(Tyrosinase)PF12142(PPO1_DWL) | 4 | ARG A 279ALA A 51ASP A 146GLY A 150 | None | 1.09A | 1e7bA-1bt2A:0.1 | 1e7bA-1bt2A:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dab | P.69 PERTACTIN (Bordetellapertussis) |
PF03212(Pertactin) | 4 | ARG A 288ALA A 285ASP A 265GLY A 263 | None | 1.02A | 1e7bA-1dabA:undetectable | 1e7bA-1dabA:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g0v | PROTEINASE A (Saccharomycescerevisiae) |
PF00026(Asp) | 4 | LYS A 187ALA A 188ASP A 126GLY A 124 | NoneNoneMAN A 329 ( 4.9A)None | 1.21A | 1e7bA-1g0vA:undetectable | 1e7bA-1g0vA:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gu3 | ENDOGLUCANASE C (Cellulomonasfimi) |
PF02018(CBM_4_9) | 4 | ARG A 75ALA A 126ASP A 90GLY A 79 | BGC A 601 (-3.0A)BGC A 602 ( 4.5A)NoneNone | 0.90A | 1e7bA-1gu3A:undetectable | 1e7bA-1gu3A:13.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kyo | LIGHT CHAIN (VL) OFFV-FRAGMENT (Mus musculus) |
PF07686(V-set) | 4 | ARG K 24ALA K 25ASP K 70GLY K 68 | None | 0.98A | 1e7bA-1kyoK:undetectable | 1e7bA-1kyoK:10.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m5q | SMALL NUCLEARRIBONUCLEOPROTEINHOMOLOG (Pyrobaculumaerophilum) |
no annotation | 4 | ARG A 83LYS A 87ALA A 86ASP A 81 | None | 1.05A | 1e7bA-1m5qA:undetectable | 1e7bA-1m5qA:12.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qag | UTROPHIN ACTINBINDING REGION (Homo sapiens) |
PF00307(CH) | 4 | ARG A 86ALA A 89ASP A 117GLY A 112 | None | 1.19A | 1e7bA-1qagA:undetectable | 1e7bA-1qagA:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rwr | FILAMENTOUSHEMAGGLUTININ (Bordetellapertussis) |
PF05860(Haemagg_act) | 4 | ARG A 242ALA A 262ASP A 218GLY A 240 | None | 0.95A | 1e7bA-1rwrA:undetectable | 1e7bA-1rwrA:18.49 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 5 | ARG A 209LYS A 212ALA A 213ASP A 324GLY A 328 | DKA A1001 ( 4.6A)NoneDKA A1001 ( 4.0A)DKA A1001 (-4.7A)DKA A1001 ( 4.1A) | 0.66A | 1e7bA-1tf0A:47.7 | 1e7bA-1tf0A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uok | OLIGO-1,6-GLUCOSIDASE (Bacillus cereus) |
PF00128(Alpha-amylase)PF16657(Malt_amylase_C) | 4 | ARG A 419ALA A 418ASP A 385GLY A 414 | None | 1.16A | 1e7bA-1uokA:undetectable | 1e7bA-1uokA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1urh | 3-MERCAPTOPYRUVATESULFURTRANSFERASE (Escherichiacoli) |
PF00581(Rhodanese) | 4 | ARG A 178ALA A 181ASP A 184GLY A 193 | None | 1.13A | 1e7bA-1urhA:0.0 | 1e7bA-1urhA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1us4 | PUTATIVE GLUR0LIGAND BINDING CORE (Thermusthermophilus) |
PF16868(NMT1_3) | 4 | ARG A 118ALA A 117ASP A 120GLY A 122 | None | 0.98A | 1e7bA-1us4A:undetectable | 1e7bA-1us4A:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v5v | AMINOMETHYLTRANSFERASE (Pyrococcushorikoshii) |
PF01571(GCV_T)PF08669(GCV_T_C) | 4 | ARG A 162ALA A 165ASP A 172GLY A 170 | None | 1.19A | 1e7bA-1v5vA:undetectable | 1e7bA-1v5vA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aip | PROTEIN C ACTIVATOR (Agkistrodoncontortrix) |
PF00089(Trypsin) | 4 | ARG A 95ALA A 177ASP A 96GLY A 175 | None | 0.91A | 1e7bA-2aipA:undetectable | 1e7bA-2aipA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cev | PROTEIN (ARGINASE) ([Bacillus]caldovelox) |
PF00491(Arginase) | 4 | ARG A 18LYS A 53ALA A 54ASP A 12 | None | 1.14A | 1e7bA-2cevA:0.0 | 1e7bA-2cevA:20.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d2r | UNDECAPRENYLPYROPHOSPHATESYNTHASE (Helicobacterpylori) |
PF01255(Prenyltransf) | 4 | ARG A 26LYS A 20ALA A 19GLY A 14 | None | 1.08A | 1e7bA-2d2rA:undetectable | 1e7bA-2d2rA:17.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2epg | HYPOTHETICAL PROTEINTTHA1785 (Thermusthermophilus) |
PF01139(RtcB) | 4 | ARG A 297ALA A 295ASP A 325GLY A 174 | None | 0.94A | 1e7bA-2epgA:undetectable | 1e7bA-2epgA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f3o | PYRUVATEFORMATE-LYASE 2 (Archaeoglobusfulgidus) |
PF01228(Gly_radical)PF02901(PFL-like) | 4 | ARG A 372ALA A 347ASP A 401GLY A 344 | None | 0.97A | 1e7bA-2f3oA:undetectable | 1e7bA-2f3oA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fuk | XC6422 PROTEIN (Xanthomonascampestris) |
PF12146(Hydrolase_4) | 4 | ARG A 78ALA A 84ASP A 96GLY A 17 | None | 1.02A | 1e7bA-2fukA:0.5 | 1e7bA-2fukA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ghp | U4/U6SNRNA-ASSOCIATEDSPLICING FACTORPRP24 (Saccharomycescerevisiae) |
PF00076(RRM_1) | 4 | ARG A 89ALA A 88ASP A 91GLY A 65 | None | 0.89A | 1e7bA-2ghpA:undetectable | 1e7bA-2ghpA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iou | PERTACTINEXTRACELLULAR DOMAIN (Bordetellabronchiseptica) |
PF03212(Pertactin) | 4 | ARG G 320ALA G 317ASP G 297GLY G 295 | None | 1.04A | 1e7bA-2iouG:undetectable | 1e7bA-2iouG:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j0j | FOCAL ADHESIONKINASE 1 (Gallus gallus) |
PF00373(FERM_M)PF07714(Pkinase_Tyr) | 4 | ARG A 252ALA A 273ASP A 254GLY A 275 | None | 0.97A | 1e7bA-2j0jA:undetectable | 1e7bA-2j0jA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j7p | CELL DIVISIONPROTEIN FTSY (Thermusaquaticus) |
PF00448(SRP54)PF02881(SRP54_N) | 4 | ARG D 124ALA D 120ASP D 287GLY D 285 | None | 1.04A | 1e7bA-2j7pD:undetectable | 1e7bA-2j7pD:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p0n | HYPOTHETICAL PROTEINNMB1532 (Neisseriameningitidis) |
PF01814(Hemerythrin) | 4 | ARG A 166ALA A 165ASP A 69GLY A 160 | None | 1.04A | 1e7bA-2p0nA:undetectable | 1e7bA-2p0nA:15.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p3x | POLYPHENOL OXIDASE,CHLOROPLAST (Vitis vinifera) |
PF00264(Tyrosinase)PF12142(PPO1_DWL) | 4 | ARG A 277ALA A 50ASP A 145GLY A 149 | None | 1.15A | 1e7bA-2p3xA:undetectable | 1e7bA-2p3xA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q47 | PROBABLETYROSINE-PROTEINPHOSPHATASEAT1G05000 (Arabidopsisthaliana) |
PF03162(Y_phosphatase2) | 4 | ARG A 188ALA A 183ASP A 191GLY A 158 | SO4 A 203 ( 4.2A)NoneNoneNone | 1.15A | 1e7bA-2q47A:undetectable | 1e7bA-2q47A:13.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qtv | SMALL COPII COATGTPASE SAR1 (Saccharomycescerevisiae) |
PF00025(Arf) | 4 | ARG B 105ALA B 109ASP B 32GLY B 30 | None | 1.19A | 1e7bA-2qtvB:undetectable | 1e7bA-2qtvB:15.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w1q | HYALURONOGLUCOSAMINIDASE (Clostridiumperfringens) |
PF00754(F5_F8_type_C) | 4 | ARG A 865ALA A 942ASP A 831GLY A 829 | None | 1.14A | 1e7bA-2w1qA:undetectable | 1e7bA-2w1qA:17.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wtb | FATTY ACIDMULTIFUNCTIONALPROTEIN (ATMFP2) (Arabidopsisthaliana) |
PF00378(ECH_1)PF00725(3HCDH)PF02737(3HCDH_N) | 4 | ARG A 49ALA A 19ASP A 51GLY A 17 | None | 0.98A | 1e7bA-2wtbA:undetectable | 1e7bA-2wtbA:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xlr | FLAVIN-CONTAININGMONOOXYGENASE (Methylophagaaminisulfidivorans) |
PF00743(FMO-like) | 4 | ARG A 115LYS A 118ALA A 119ASP A 88 | None | 1.07A | 1e7bA-2xlrA:undetectable | 1e7bA-2xlrA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yv2 | SUCCINYL-COASYNTHETASE ALPHACHAIN (Aeropyrumpernix) |
PF00549(Ligase_CoA)PF02629(CoA_binding) | 4 | LYS A 121ALA A 123ASP A 93GLY A 95 | None | 0.92A | 1e7bA-2yv2A:undetectable | 1e7bA-2yv2A:17.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aq2 | 6B PROTEIN (Agrobacteriumvitis) |
PF02027(RolB_RolC) | 4 | ARG A 12ALA A 72ASP A 10GLY A 76 | None | 1.03A | 1e7bA-3aq2A:undetectable | 1e7bA-3aq2A:14.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3db2 | PUTATIVENADPH-DEPENDENTOXIDOREDUCTASE (Desulfitobacteriumhafniense) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | ARG A 63ALA A 8ASP A 65GLY A 6 | None | 1.05A | 1e7bA-3db2A:undetectable | 1e7bA-3db2A:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fha | ENDO-BETA-N-ACETYLGLUCOSAMINIDASE (Glutamicibacterprotophormiae) |
PF03644(Glyco_hydro_85) | 4 | ARG A 223ALA A 215ASP A 210GLY A 212 | None | 0.71A | 1e7bA-3fhaA:undetectable | 1e7bA-3fhaA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h0g | DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB3DNA-DIRECTED RNAPOLYMERASES I, II,AND III SUBUNITRPABC4 (Schizosaccharomycespombe) |
PF01000(RNA_pol_A_bac)PF01193(RNA_pol_L)PF03604(DNA_RNApol_7kD) | 4 | ARG L 63LYS C 170ASP C 46GLY C 163 | None | 0.93A | 1e7bA-3h0gL:undetectable | 1e7bA-3h0gL:7.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hj4 | MINOREDITOSOME-ASSOCIATEDTUTASE (Trypanosomabrucei) |
no annotation | 4 | ARG A 17ALA A 158ASP A 237GLY A 241 | None | 1.13A | 1e7bA-3hj4A:undetectable | 1e7bA-3hj4A:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hsk | ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Candidaalbicans) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 4 | LYS A 109ALA A 108ASP A 88GLY A 91 | None | 1.15A | 1e7bA-3hskA:undetectable | 1e7bA-3hskA:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i9v | NADH-QUINONEOXIDOREDUCTASESUBUNIT 4 (Thermusthermophilus) |
PF00346(Complex1_49kDa) | 4 | ARG 4 249ALA 4 349ASP 4 247GLY 4 237 | None | 1.05A | 1e7bA-3i9v4:undetectable | 1e7bA-3i9v4:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ilh | TWO COMPONENTRESPONSE REGULATOR (Cytophagahutchinsonii) |
PF00072(Response_reg) | 4 | ARG A 103LYS A 107ALA A 106ASP A 101 | None | 1.18A | 1e7bA-3ilhA:undetectable | 1e7bA-3ilhA:12.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lvr | ARF-GAP WITH SH3DOMAIN, ANK REPEATAND PHDOMAIN-CONTAININGPROTEIN 3,ADP-RIBOSYLATIONFACTOR 6 (Homo sapiens;syntheticconstruct) |
PF00025(Arf)PF01412(ArfGap)PF12796(Ank_2) | 4 | ARG E 95ALA E 99ASP E 22GLY E 20 | NoneNone CA E 739 (-4.9A)None | 1.10A | 1e7bA-3lvrE:undetectable | 1e7bA-3lvrE:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n1q | DESERT HEDGEHOGPROTEIN (Homo sapiens) |
no annotation | 4 | ARG B 102ALA B 188ASP B 172GLY B 61 | None | 1.12A | 1e7bA-3n1qB:undetectable | 1e7bA-3n1qB:14.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ne5 | CATION EFFLUX SYSTEMPROTEIN CUSA (Escherichiacoli) |
PF00873(ACR_tran) | 4 | ARG A 867LYS A 871ALA A 868GLY A 472 | None | 0.91A | 1e7bA-3ne5A:undetectable | 1e7bA-3ne5A:19.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ozy | PUTATIVE MANDELATERACEMASE (Bordetellabronchiseptica) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ARG A 63LYS A 62ALA A 64GLY A 70 | None | 1.15A | 1e7bA-3ozyA:undetectable | 1e7bA-3ozyA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pco | PHENYLALANYL-TRNASYNTHETASE, BETACHAIN (Escherichiacoli) |
PF01588(tRNA_bind)PF03147(FDX-ACB)PF03483(B3_4)PF03484(B5) | 4 | ARG B 177ALA B 176ASP B 168GLY B 171 | None | 1.13A | 1e7bA-3pcoB:undetectable | 1e7bA-3pcoB:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s1v | PROBABLETRANSALDOLASE (Thermoplasmaacidophilum) |
PF00923(TAL_FSA) | 4 | ARG A 74LYS A 75ALA A 73GLY A 68 | None | 0.97A | 1e7bA-3s1vA:undetectable | 1e7bA-3s1vA:16.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t8l | ADENINE DEAMINASE 2 (Agrobacteriumfabrum) |
PF01979(Amidohydro_1)PF13382(Adenine_deam_C) | 4 | ARG A 344ALA A 345ASP A 335GLY A 342 | None | 1.03A | 1e7bA-3t8lA:undetectable | 1e7bA-3t8lA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tjz | ADP-RIBOSYLATIONFACTOR 1 (Saccharomycescerevisiae) |
PF00025(Arf) | 4 | ARG A 99ALA A 103ASP A 26GLY A 24 | None | 1.15A | 1e7bA-3tjzA:undetectable | 1e7bA-3tjzA:13.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3top | MALTASE-GLUCOAMYLASE, INTESTINAL (Homo sapiens) |
PF00088(Trefoil)PF01055(Glyco_hydro_31)PF16863(NtCtMGAM_N) | 4 | ARG A1681ALA A1739ASP A1690GLY A1688 | None | 1.17A | 1e7bA-3topA:undetectable | 1e7bA-3topA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aie | GLUCAN1,6-ALPHA-GLUCOSIDASE (Lactobacillusacidophilus) |
PF00128(Alpha-amylase)PF16657(Malt_amylase_C) | 4 | ARG A 405ALA A 404ASP A 372GLY A 400 | None | 1.18A | 1e7bA-4aieA:undetectable | 1e7bA-4aieA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bh6 | APC/C ACTIVATORPROTEIN CDH1 (Saccharomycescerevisiae) |
PF00400(WD40)PF12894(ANAPC4_WD40) | 4 | ARG A 362ALA A 348ASP A 345GLY A 324 | None | 1.03A | 1e7bA-4bh6A:undetectable | 1e7bA-4bh6A:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bzi | SAR1P (Saccharomycescerevisiae) |
PF00025(Arf) | 4 | ARG B 105ALA B 109ASP B 32GLY B 30 | None | 1.19A | 1e7bA-4bziB:undetectable | 1e7bA-4bziB:16.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dag | FUSION GLYCOPROTEINF0 (Humanmetapneumovirus) |
PF00523(Fusion_gly) | 4 | ARG A 304ALA A 288ASP A 306GLY A 308 | None | 1.19A | 1e7bA-4dagA:undetectable | 1e7bA-4dagA:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4di1 | ENOYL-COA HYDRATASEECHA17 (Mycobacteriummarinum) |
PF00378(ECH_1) | 4 | ARG A 44ALA A 14ASP A 46GLY A 12 | None | 0.99A | 1e7bA-4di1A:undetectable | 1e7bA-4di1A:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eaa | PEROSAMINEN-ACETYLTRANSFERASE (Caulobactervibrioides) |
PF00132(Hexapep) | 4 | ARG A 166ALA A 147ASP A 184GLY A 164 | None | 1.12A | 1e7bA-4eaaA:undetectable | 1e7bA-4eaaA:15.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eaa | PEROSAMINEN-ACETYLTRANSFERASE (Caulobactervibrioides) |
PF00132(Hexapep) | 4 | ARG A 166ALA A 148ASP A 184GLY A 164 | None | 1.02A | 1e7bA-4eaaA:undetectable | 1e7bA-4eaaA:15.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h2h | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME (Salipigerbermudensis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ARG A 167ALA A 166ASP A 172GLY A 194 | None | 1.16A | 1e7bA-4h2hA:undetectable | 1e7bA-4h2hA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h7m | ENDO-1,4-BETA-GLUCANASE (Trichodermaharzianum) |
PF01670(Glyco_hydro_12) | 4 | ARG A 100ALA A 101ASP A 133GLY A 135 | None | 0.92A | 1e7bA-4h7mA:undetectable | 1e7bA-4h7mA:13.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hav | RAN-SPECIFICGTPASE-ACTIVATINGPROTEIN 1 (Saccharomycescerevisiae) |
PF00638(Ran_BP1) | 4 | ARG B 90ALA B 91ASP B 129GLY B 107 | None | 1.12A | 1e7bA-4havB:undetectable | 1e7bA-4havB:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i8q | PUTATIVE BETAINEALDEHYDEDEHYROGENASE (Solanumlycopersicum) |
PF00171(Aldedh) | 4 | ARG A 63ALA A 62ASP A 65GLY A 67 | None | 0.95A | 1e7bA-4i8qA:undetectable | 1e7bA-4i8qA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jb6 | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 2 (Pseudomonasaeruginosa) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | ARG A 253ALA A 252ASP A 88GLY A 90 | None | 1.20A | 1e7bA-4jb6A:undetectable | 1e7bA-4jb6A:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k2u | ANTIBODY LIGHT CHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 4 | ARG L 24ALA L 25ASP L 70GLY L 68 | None | 1.10A | 1e7bA-4k2uL:undetectable | 1e7bA-4k2uL:15.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ko2 | PERIPLASMIC [NIFESE]HYDROGENASE SMALLSUBUNIT (Desulfomicrobiumbaculatum) |
PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C) | 4 | ARG S 146ALA S 128ASP S 147GLY S 130 | None | 1.11A | 1e7bA-4ko2S:0.3 | 1e7bA-4ko2S:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kp2 | HOMOACONITASE LARGESUBUNIT (Methanocaldococcusjannaschii) |
PF00330(Aconitase) | 4 | ARG A 306ALA A 333ASP A 309GLY A 300 | None | 0.80A | 1e7bA-4kp2A:undetectable | 1e7bA-4kp2A:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lis | UDP-GLUCOSE4-EPIMERASE (Aspergillusnidulans) |
PF16363(GDP_Man_Dehyd) | 4 | ARG A 312ALA A 249ASP A 241GLY A 247 | IOD A 405 (-3.7A)UPG A 401 (-3.2A)NoneNone | 0.94A | 1e7bA-4lisA:undetectable | 1e7bA-4lisA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m8u | OLIGO-1,6-GLUCOSIDASE 1 (Bacillussubtilis) |
PF00128(Alpha-amylase)PF16657(Malt_amylase_C) | 4 | ARG A 422ALA A 421ASP A 387GLY A 417 | None | 1.20A | 1e7bA-4m8uA:undetectable | 1e7bA-4m8uA:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mio | INOSITOL2-DEHYDROGENASE/D-CHIRO-INOSITOL3-DEHYDROGENASE (Lactobacilluscasei) |
PF01408(GFO_IDH_MocA) | 4 | LYS A 53ALA A 52ASP A 64GLY A 6 | None | 1.14A | 1e7bA-4mioA:2.3 | 1e7bA-4mioA:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4obu | PYRIDOXAL-DEPENDENTDECARBOXYLASE DOMAINPROTEIN ([Ruminococcus]gnavus) |
no annotation | 4 | ARG E 210ALA E 185ASP E 232GLY E 183 | None | 1.07A | 1e7bA-4obuE:undetectable | 1e7bA-4obuE:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pfq | HYPOXANTHINEPHOSPHORIBOSYLTRANSFERASE (Brachybacteriumfaecium) |
PF00156(Pribosyltran) | 4 | ARG A 157ALA A 154ASP A 174GLY A 172 | None | 1.01A | 1e7bA-4pfqA:undetectable | 1e7bA-4pfqA:18.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 5 | ARG A 209LYS A 212ALA A 213ASP A 324GLY A 328 | NPS A 602 (-3.6A)NoneNPS A 602 (-3.3A)NPS A 602 ( 4.4A)NPS A 602 (-3.8A) | 0.86A | 1e7bA-4po0A:46.2 | 1e7bA-4po0A:74.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rcn | LONG-CHAIN ACYL-COACARBOXYLASE (Mycobacteriumavium) |
PF00289(Biotin_carb_N)PF01039(Carboxyl_trans)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | ARG A 688LYS A 692ALA A 691GLY A 686 | None | 1.02A | 1e7bA-4rcnA:undetectable | 1e7bA-4rcnA:18.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wgx | MOLINATE HYDROLASE (Gulosibactermolinativorax) |
PF01979(Amidohydro_1) | 4 | ARG A 86ALA A 85ASP A 347GLY A 80 | None | 0.98A | 1e7bA-4wgxA:undetectable | 1e7bA-4wgxA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xvj | ANTIBODY HEAVY CHAINVARIABLE DOMAIN (Homo sapiens) |
PF07686(V-set) | 4 | ARG H 38ALA H 40ASP H 90GLY H 136 | None | 1.16A | 1e7bA-4xvjH:undetectable | 1e7bA-4xvjH:11.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zhs | ASPARTATESEMIALDEHYDEDEHYDROGENASE (Trichophytonrubrum) |
no annotation | 4 | LYS D 111ALA D 110ASP D 90GLY D 93 | None | 1.15A | 1e7bA-4zhsD:0.1 | 1e7bA-4zhsD:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4znj | PHAGE TERMINASELARGE SUBUNIT (Thermus virusP74-26) |
PF03237(Terminase_6) | 4 | ARG A 170ALA A 141ASP A 144GLY A 63 | None | 1.06A | 1e7bA-4znjA:undetectable | 1e7bA-4znjA:16.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a31 | THEANAPHASE-PROMOTINGCOMPLEX CHAIN R (Homo sapiens) |
PF00400(WD40)PF12894(ANAPC4_WD40) | 4 | ARG R 286ALA R 272ASP R 269GLY R 248 | None | 1.11A | 1e7bA-5a31R:undetectable | 1e7bA-5a31R:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ce9 | POLYPHENOL OXIDASE (Juglans regia) |
PF00264(Tyrosinase)PF12142(PPO1_DWL) | 4 | ARG A 278ALA A 50ASP A 145GLY A 149 | None | 1.16A | 1e7bA-5ce9A:undetectable | 1e7bA-5ce9A:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cqb | DITRANS,POLYCIS-UNDECAPRENYL-DIPHOSPHATESYNTHASE((2E,6E)-FARNESYL-DIPHOSPHATE SPECIFIC) (Escherichiacoli) |
PF01255(Prenyltransf) | 4 | ARG A 39LYS A 33ALA A 32GLY A 27 | None | 1.00A | 1e7bA-5cqbA:undetectable | 1e7bA-5cqbA:16.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5do8 | LMO0184 PROTEIN (Listeriamonocytogenes) |
no annotation | 4 | ARG B 417ALA B 416ASP B 384GLY B 412 | BGC B 601 ( 4.8A)NoneNoneNone | 1.19A | 1e7bA-5do8B:undetectable | 1e7bA-5do8B:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fur | TRANSCRIPTIONINITIATION FACTORTFIID SUBUNIT 6 (Homo sapiens) |
PF07571(TAF6_C) | 4 | ARG J 335ALA J 338ASP J 331GLY J 379 | None | 0.97A | 1e7bA-5furJ:2.2 | 1e7bA-5furJ:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hxa | ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE(UDP-FORMING) (Paraburkholderiaxenovorans) |
PF00982(Glyco_transf_20) | 4 | ARG A 150ALA A 146ASP A 189GLY A 159 | None | 1.19A | 1e7bA-5hxaA:undetectable | 1e7bA-5hxaA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5idu | ACYL-COADEHYDROGENASE DOMAINPROTEIN (Paraburkholderiaphymatum) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | ARG A 86ALA A 258ASP A 97GLY A 262 | None | 1.16A | 1e7bA-5iduA:undetectable | 1e7bA-5iduA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jsc | PUTATIVE ACYL-COADEHYDROGENASE (Paraburkholderiaxenovorans) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | ARG A 87ALA A 259ASP A 98GLY A 263 | None | 1.15A | 1e7bA-5jscA:undetectable | 1e7bA-5jscA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k6o | B-GLUCOSIDASE (metagenome) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | ARG A 538ALA A 510ASP A 540GLY A 501 | GAL A1000 (-4.4A)GAL A1000 ( 4.4A)NoneNone | 1.04A | 1e7bA-5k6oA:undetectable | 1e7bA-5k6oA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kov | PL-2 SCFV CHAIN (Mus musculus) |
PF07686(V-set) | 4 | ARG C1024ALA C1025ASP C1070GLY C1068 | None | 1.20A | 1e7bA-5kovC:undetectable | 1e7bA-5kovC:15.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l1x | HMPV F1 SUBUNIT (Humanmetapneumovirus) |
PF00523(Fusion_gly) | 4 | ARG B 304ALA B 288ASP B 306GLY B 308 | None | 1.18A | 1e7bA-5l1xB:undetectable | 1e7bA-5l1xB:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mgv | PHENYLALANINE--TRNALIGASE,MITOCHONDRIAL (Homo sapiens) |
PF01409(tRNA-synt_2d)PF03147(FDX-ACB) | 4 | ARG A 271ALA A 268ASP A 133GLY A 131 | None | 1.17A | 1e7bA-5mgvA:undetectable | 1e7bA-5mgvA:22.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 4 | ARG A 208ALA A 212ASP A 323GLY A 327 | None | 0.43A | 1e7bA-5oriA:45.9 | 1e7bA-5oriA:74.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 4 | ARG A 208LYS A 211ALA A 212ASP A 323 | None | 1.11A | 1e7bA-5oriA:45.9 | 1e7bA-5oriA:74.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uf8 | POTENTIALADP-RIBOSYLATIONFACTOR (Candidaalbicans) |
PF00025(Arf) | 4 | ARG A 99ALA A 103ASP A 26GLY A 24 | None | 1.17A | 1e7bA-5uf8A:undetectable | 1e7bA-5uf8A:13.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v0t | ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE(UDP-FORMING) (Paraburkholderiaxenovorans) |
PF00982(Glyco_transf_20) | 4 | ARG A 151ALA A 147ASP A 190GLY A 160 | None | 1.12A | 1e7bA-5v0tA:undetectable | 1e7bA-5v0tA:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wzm | GROUP IIE SECRETORYPHOSPHOLIPASE A2 (Homo sapiens) |
no annotation | 4 | LYS A 107ALA A 109ASP A 37GLY A 24 | NoneNoneNone CA A 209 (-4.2A) | 1.12A | 1e7bA-5wzmA:undetectable | 1e7bA-5wzmA:9.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 4 | ARG A 209ALA A 213ASP A 324GLY A 328 | None | 0.49A | 1e7bA-5yxeA:47.6 | 1e7bA-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 4 | ARG A 209LYS A 212ALA A 213GLY A 328 | None | 0.63A | 1e7bA-5yxeA:47.6 | 1e7bA-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bq1 | PHOSPHATIDYLINOSITOL4-KINASE III ALPHA(PI4KA) (Homo sapiens) |
no annotation | 4 | ARG A1856ALA A1888ASP A1854GLY A1892 | None | 1.10A | 1e7bA-6bq1A:undetectable | 1e7bA-6bq1A:0.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c2j | RNAP2 (Escherichiavirus N4) |
no annotation | 4 | ARG B 91ALA B 94ASP B 389GLY B 89 | None | 1.13A | 1e7bA-6c2jB:undetectable | 1e7bA-6c2jB:9.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dzs | HOMOSERINEDEHYDROGENASE (Mycolicibacteriumhassiacum) |
no annotation | 4 | ARG A 72ALA A 11ASP A 74GLY A 9 | None | 0.87A | 1e7bA-6dzsA:1.2 | 1e7bA-6dzsA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ehv | SCFV ABVANCE:INCREASING OURKNOWLEDGE OFANTIBODY STRUCTURALSPACE TO ENABLEFASTER AND BETTERDECISION MAKING INDRUG DISCOVERY (Homo sapiens) |
no annotation | 4 | ARG X 158ALA X 159ASP X 205GLY X 203 | None | 1.06A | 1e7bA-6ehvX:undetectable | 1e7bA-6ehvX:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f5d | ATP SYNTHASE SUBUNITBETA (Trypanosomabrucei) |
no annotation | 4 | ARG D 361ALA D 134ASP D 335GLY D 155 | None | 1.15A | 1e7bA-6f5dD:undetectable | 1e7bA-6f5dD:9.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f8z | ALPHA-1,2-MANNOSIDASE, PUTATIVE (Bacteroidesthetaiotaomicron) |
no annotation | 4 | LYS A 200ALA A 199ASP A 396GLY A 394 | None | 1.19A | 1e7bA-6f8zA:undetectable | 1e7bA-6f8zA:8.21 |