SIMILAR PATTERNS OF AMINO ACIDS FOR 1E7A_B_PFLB4001_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a0j | TRYPSIN (Salmo salar) |
PF00089(Trypsin) | 5 | LEU A 163ILE A 162VAL A 199GLY A 211LEU A 160 | None | 0.98A | 1e7aB-1a0jA:undetectable | 1e7aB-1a0jA:15.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dj2 | ADENYLOSUCCINATESYNTHETASE (Arabidopsisthaliana) |
PF00709(Adenylsucc_synt) | 5 | LEU A 347ILE A 428LEU A 361VAL A 424LEU A 333 | None | 1.17A | 1e7aB-1dj2A:0.0 | 1e7aB-1dj2A:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e0c | SULFURTRANSFERASE (Azotobactervinelandii) |
PF00581(Rhodanese) | 5 | ILE A 99PHE A 73LEU A 72VAL A 28LEU A 30 | None | 1.12A | 1e7aB-1e0cA:undetectable | 1e7aB-1e0cA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fzq | ADP-RIBOSYLATIONFACTOR-LIKE PROTEIN3 (Mus musculus) |
PF00025(Arf) | 5 | ILE A 89LEU A 10VAL A 166GLY A 169LEU A 37 | None | 1.08A | 1e7aB-1fzqA:undetectable | 1e7aB-1fzqA:15.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h9h | TRYPSIN (Sus scrofa) |
PF00089(Trypsin) | 5 | LEU E 105ILE E 106LEU E 209VAL E 31GLY E 43 | None | 1.25A | 1e7aB-1h9hE:undetectable | 1e7aB-1h9hE:15.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jik | TYROSYL-TRNASYNTHETASE (Staphylococcusaureus) |
PF00579(tRNA-synt_1b) | 5 | LEU A 9ILE A 15LEU A 35GLY A 218LEU A 28 | None | 1.16A | 1e7aB-1jikA:undetectable | 1e7aB-1jikA:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mb0 | CELL DIVISIONRESPONSE REGULATORDIVK (Caulobactervibrioides) |
PF00072(Response_reg) | 5 | LEU A 6ILE A 50VAL A 64GLY A 61LEU A 39 | None | 1.26A | 1e7aB-1mb0A:undetectable | 1e7aB-1mb0A:13.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mbq | TRYPSIN (Oncorhynchusketa) |
PF00089(Trypsin) | 5 | LEU A 105ILE A 106LEU A 209VAL A 31GLY A 44 | None | 1.25A | 1e7aB-1mbqA:undetectable | 1e7aB-1mbqA:16.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 8 | LEU A 387ILE A 388ASN A 391PHE A 403LEU A 407ARG A 410GLY A 434LEU A 453 | None | 0.63A | 1e7aB-1tf0A:47.1 | 1e7aB-1tf0A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 6 | LEU A 387ILE A 388LEU A 407VAL A 433GLY A 434LEU A 453 | None | 0.69A | 1e7aB-1tf0A:47.1 | 1e7aB-1tf0A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vhi | EPSTEIN BARR VIRUSNUCLEAR ANTIGEN-1 (Humangammaherpesvirus4) |
PF02905(EBV-NA1) | 5 | LEU A 485PHE A 562LEU A 533VAL A 507LEU A 575 | None | 1.17A | 1e7aB-1vhiA:undetectable | 1e7aB-1vhiA:12.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y4c | MALTOSE BINDINGPROTEIN FUSED WITHDESIGNED HELICALPROTEIN (Escherichiacoli) |
PF13416(SBP_bac_8) | 5 | ILE A 9LEU A 262VAL A 293GLY A 16LEU A 284 | None | 1.25A | 1e7aB-1y4cA:undetectable | 1e7aB-1y4cA:23.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y9a | NADP-DEPENDENTALCOHOLDEHYDROGENASE (Entamoebahistolytica) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | LEU A 189ILE A 164ARG A 301VAL A 240GLY A 263 | None | 1.24A | 1e7aB-1y9aA:undetectable | 1e7aB-1y9aA:20.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ysx | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 5 | LEU A 387ILE A 388ASN A 391PHE A 403LEU A 407 | None4EB A1000 ( 4.6A)4EB A1000 (-3.5A)4EB A1000 ( 4.1A)4EB A1000 (-4.5A) | 0.70A | 1e7aB-1ysxA:6.0 | 1e7aB-1ysxA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aw5 | NADP-DEPENDENT MALICENZYME (Homo sapiens) |
PF00390(malic)PF03949(Malic_M) | 5 | ILE A 382LEU A 376VAL A 334GLY A 301LEU A 364 | None | 1.12A | 1e7aB-2aw5A:undetectable | 1e7aB-2aw5A:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bhv | COMB10 (Helicobacterpylori) |
PF03743(TrbI) | 5 | ILE A 354LEU A 233VAL A 194GLY A 220LEU A 182 | None | 1.19A | 1e7aB-2bhvA:undetectable | 1e7aB-2bhvA:18.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eek | TRYPSIN-1 (Gadus morhua) |
PF00089(Trypsin) | 5 | LEU A 105ILE A 106LEU A 209VAL A 31GLY A 44 | None | 1.26A | 1e7aB-2eekA:undetectable | 1e7aB-2eekA:16.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eek | TRYPSIN-1 (Gadus morhua) |
PF00089(Trypsin) | 5 | LEU A 163ILE A 162VAL A 199GLY A 211LEU A 160 | None | 0.99A | 1e7aB-2eekA:undetectable | 1e7aB-2eekA:16.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2elc | ANTHRANILATEPHOSPHORIBOSYLTRANSFERASE (Thermusthermophilus) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N) | 5 | LEU A 74ILE A 76LEU A 205VAL A 215GLY A 191 | None | 1.13A | 1e7aB-2elcA:undetectable | 1e7aB-2elcA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ell | ACIDIC LEUCINE-RICHNUCLEARPHOSPHOPROTEIN 32FAMILY MEMBER B (Homo sapiens) |
PF14580(LRR_9) | 5 | LEU A 67ILE A 41VAL A 59GLY A 60LEU A 56 | None | 1.16A | 1e7aB-2ellA:undetectable | 1e7aB-2ellA:14.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mqw | 26S PROTEASOMEREGULATORY SUBUNITRPN9 (Saccharomycescerevisiae) |
no annotation | 5 | LEU A 11ILE A 10LEU A 41VAL A 66LEU A 61 | None | 1.24A | 1e7aB-2mqwA:undetectable | 1e7aB-2mqwA:15.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q03 | UNCHARACTERIZEDPROTEIN (Shewanelladenitrificans) |
PF11528(DUF3224) | 5 | LEU A 46ILE A 10PHE A 100LEU A 85LEU A 134 | None | 1.14A | 1e7aB-2q03A:undetectable | 1e7aB-2q03A:12.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q2r | GLUCOKINASE 1,PUTATIVE (Trypanosomacruzi) |
PF02685(Glucokinase) | 5 | LEU A 132LEU A 304VAL A 289GLY A 290LEU A 187 | BGC A1001 ( 4.8A)NoneNoneNoneNone | 1.12A | 1e7aB-2q2rA:1.7 | 1e7aB-2q2rA:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vhl | N-ACETYLGLUCOSAMINE-6-PHOSPHATEDEACETYLASE (Bacillussubtilis) |
PF01979(Amidohydro_1) | 5 | LEU A 379ILE A 381VAL A 24GLY A 25LEU A 55 | None | 1.14A | 1e7aB-2vhlA:undetectable | 1e7aB-2vhlA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x9x | CELL WALL SURFACEANCHOR FAMILYPROTEIN (Streptococcuspneumoniae) |
PF16569(GramPos_pilinBB)PF16570(GramPos_pilinD3) | 5 | ILE A 535ASN A 538PHE A 541LEU A 478GLY A 567 | None | 0.90A | 1e7aB-2x9xA:3.4 | 1e7aB-2x9xA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xgo | XCOGT (Xanthomonascampestris) |
PF13432(TPR_16)PF13844(Glyco_transf_41) | 5 | LEU A 328LEU A 231VAL A 208GLY A 209LEU A 556 | None | 1.22A | 1e7aB-2xgoA:undetectable | 1e7aB-2xgoA:23.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yys | PROLINEIMINOPEPTIDASE-RELATED PROTEIN (Thermusthermophilus) |
PF12697(Abhydrolase_6) | 5 | LEU A 81LEU A 69VAL A 10GLY A 11LEU A 15 | None | 1.19A | 1e7aB-2yysA:undetectable | 1e7aB-2yysA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aib | GLUCOSYLTRANSFERASE-SI (Streptococcusmutans) |
PF02324(Glyco_hydro_70) | 5 | ILE A 775LEU A 646VAL A 818GLY A 817LEU A 683 | None | 1.13A | 1e7aB-3aibA:undetectable | 1e7aB-3aibA:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b8y | ENDO-PECTATE LYASE (Dickeyachrysanthemi) |
PF03211(Pectate_lyase) | 5 | LEU A 243ILE A 277LEU A 266VAL A 308LEU A 296 | None | 1.09A | 1e7aB-3b8yA:undetectable | 1e7aB-3b8yA:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b90 | ENDO-PECTATE LYASE (Dickeyachrysanthemi) |
PF03211(Pectate_lyase) | 5 | LEU A 243ILE A 277LEU A 266VAL A 308LEU A 296 | None | 1.12A | 1e7aB-3b90A:undetectable | 1e7aB-3b90A:16.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b9g | IAG-NUCLEOSIDEHYDROLASE (Trypanosomavivax) |
PF01156(IU_nuc_hydro) | 5 | LEU A 96ILE A 95LEU A 13VAL A 238GLY A 239 | None | 1.22A | 1e7aB-3b9gA:undetectable | 1e7aB-3b9gA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d00 | TUNGSTENFORMYLMETHANOFURANDEHYDROGENASESUBUNIT E (Syntrophusaciditrophicus) |
PF02663(FmdE) | 5 | LEU A 130ILE A 134PHE A 84VAL A 29GLY A 32 | None | 1.26A | 1e7aB-3d00A:undetectable | 1e7aB-3d00A:16.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dc7 | PUTATIVEUNCHARACTERIZEDPROTEIN LP_3323 (Lactobacillusplantarum) |
PF13472(Lipase_GDSL_2) | 5 | LEU A 46ILE A 45LEU A 180VAL A 211GLY A 208 | None | 1.22A | 1e7aB-3dc7A:undetectable | 1e7aB-3dc7A:16.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dtn | PUTATIVEMETHYLTRANSFERASEMM_2633 (Methanosarcinamazei) |
PF13649(Methyltransf_25) | 5 | ILE A 95LEU A 128ARG A 131GLY A 50LEU A 47 | None | 0.95A | 1e7aB-3dtnA:undetectable | 1e7aB-3dtnA:17.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fpc | NADP-DEPENDENTALCOHOLDEHYDROGENASE (Entamoebahistolytica;Thermoanaerobacterbrockii) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | LEU A 189ILE A 164ARG A 301VAL A 240GLY A 263 | None | 1.23A | 1e7aB-3fpcA:undetectable | 1e7aB-3fpcA:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gg2 | SUGAR DEHYDROGENASE,UDP-GLUCOSE/GDP-MANNOSE DEHYDROGENASEFAMILY (Porphyromonasgingivalis) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 5 | LEU A 423ILE A 420LEU A 465VAL A 468GLY A 401 | None | 1.26A | 1e7aB-3gg2A:undetectable | 1e7aB-3gg2A:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3goz | LEUCINE-RICHREPEAT-CONTAININGPROTEIN (Legionellapneumophila) |
no annotation | 5 | LEU A 162ILE A 161LEU A 187GLY A 151LEU A 174 | None | 1.14A | 1e7aB-3gozA:undetectable | 1e7aB-3gozA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iyl | VP1 (Aquareovirus C) |
PF06016(Reovirus_L2) | 5 | ILE W 131LEU W 30VAL W 117GLY W 119LEU W 138 | None | 1.10A | 1e7aB-3iylW:undetectable | 1e7aB-3iylW:17.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k1t | GLUTAMATE--CYSTEINELIGASE GSHA (Methylobacillusflagellatus) |
PF08886(GshA) | 5 | LEU A 179ILE A 183LEU A 163GLY A 189LEU A 194 | None CL A 436 (-4.3A)NoneSO4 A 435 (-3.5A)None | 1.04A | 1e7aB-3k1tA:undetectable | 1e7aB-3k1tA:23.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mop | INTERLEUKIN-1RECEPTOR-ASSOCIATEDKINASE 4 (Homo sapiens) |
no annotation | 5 | LEU G 35ILE G 39LEU G 100VAL G 11LEU G 71 | None | 1.19A | 1e7aB-3mopG:undetectable | 1e7aB-3mopG:9.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n5m | ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE (Bacillusanthracis) |
PF00202(Aminotran_3) | 5 | LEU A 355ILE A 359LEU A 406VAL A 397LEU A 422 | None | 1.19A | 1e7aB-3n5mA:undetectable | 1e7aB-3n5mA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oz7 | PHOSPHOGLYCERATEKINASE (Plasmodiumfalciparum) |
PF00162(PGK) | 5 | ILE A 369PHE A 165LEU A 407GLY A 394LEU A 402 | None | 1.24A | 1e7aB-3oz7A:undetectable | 1e7aB-3oz7A:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qe7 | URACIL PERMEASE (Escherichiacoli) |
PF00860(Xan_ur_permease) | 5 | LEU A 322ILE A 326LEU A 25GLY A 30LEU A 47 | None | 1.11A | 1e7aB-3qe7A:undetectable | 1e7aB-3qe7A:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qxz | ENOYL-COAHYDRATASE/ISOMERASE (Mycobacteroidesabscessus) |
PF00378(ECH_1) | 5 | LEU A 158ILE A 129LEU A 121GLY A 109LEU A 114 | None | 1.12A | 1e7aB-3qxzA:undetectable | 1e7aB-3qxzA:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r75 | ANTHRANILATE/PARA-AMINOBENZOATESYNTHASES COMPONENTI (Burkholderialata) |
PF00117(GATase)PF00425(Chorismate_bind) | 5 | LEU A 512ILE A 516VAL A 586GLY A 602LEU A 536 | None | 1.12A | 1e7aB-3r75A:undetectable | 1e7aB-3r75A:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3re1 | UROPORPHYRINOGEN-IIISYNTHETASE (Pseudomonassyringae groupgenomosp. 3) |
PF02602(HEM4) | 5 | ILE A 233LEU A 8ARG A 10GLY A 185LEU A 247 | None | 1.15A | 1e7aB-3re1A:undetectable | 1e7aB-3re1A:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rr1 | PUTATIVED-GALACTONATEDEHYDRATASE (Ralstoniapickettii) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 6 | LEU A 182ILE A 208ARG A 166VAL A 188GLY A 186LEU A 196 | None | 1.41A | 1e7aB-3rr1A:undetectable | 1e7aB-3rr1A:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tbh | O-ACETYL SERINESULFHYDRYLASE (Leishmaniadonovani) |
PF00291(PALP) | 5 | LEU A 244ILE A 245VAL A 185GLY A 184LEU A 240 | NoneNoneLLP A 51 ( 4.2A)NoneNone | 1.10A | 1e7aB-3tbhA:undetectable | 1e7aB-3tbhA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqs | RIBOSOMAL RNA SMALLSUBUNITMETHYLTRANSFERASE A (Coxiellaburnetii) |
PF00398(RrnaAD) | 5 | LEU A 21ILE A 24VAL A 104GLY A 105LEU A 50 | None | 1.25A | 1e7aB-3tqsA:undetectable | 1e7aB-3tqsA:18.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tsr | RIBONUCLEASEINHIBITOR (Mus musculus) |
PF13516(LRR_6) | 5 | ASN E 403LEU E 385VAL E 410GLY E 409LEU E 429 | None | 1.24A | 1e7aB-3tsrE:undetectable | 1e7aB-3tsrE:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vla | EDGP (Daucus carota) |
PF14541(TAXi_C)PF14543(TAXi_N) | 5 | LEU A 332ILE A 330VAL A 361GLY A 360LEU A 279 | None | 1.10A | 1e7aB-3vlaA:undetectable | 1e7aB-3vlaA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vvj | OVALBUMIN (Dromaiusnovaehollandiae) |
PF00079(Serpin) | 5 | ILE A 122LEU A 322VAL A 42GLY A 45LEU A 175 | None | 1.10A | 1e7aB-3vvjA:undetectable | 1e7aB-3vvjA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wai | MALTOSE-BINDINGPERIPLASMIC PROTEIN,TRANSMEMBRANEOLIGOSACCHARYLTRANSFERASE (Archaeoglobusfulgidus;Escherichiacoli) |
PF13416(SBP_bac_8) | 5 | ILE A 9LEU A 262VAL A 293GLY A 16LEU A 284 | None | 1.25A | 1e7aB-3waiA:undetectable | 1e7aB-3waiA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zcw | KINESIN-LIKE PROTEINKIF11 (Homo sapiens) |
PF00225(Kinesin) | 5 | ILE A 19LEU A 316VAL A 298GLY A 296LEU A 324 | NoneNoneNone4A2 A1366 (-3.4A)None | 1.26A | 1e7aB-3zcwA:undetectable | 1e7aB-3zcwA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zog | FMN-BINDING PROTEIN (Pyrococcushorikoshii) |
PF01613(Flavin_Reduct) | 5 | LEU A 14ILE A 15LEU A 93VAL A 101GLY A 18 | None | 1.24A | 1e7aB-3zogA:undetectable | 1e7aB-3zogA:13.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c0e | NOT1 (Chaetomiumthermophilum) |
PF04054(Not1) | 5 | LEU A2007LEU A1999VAL A2016GLY A2015LEU A2082 | None | 1.21A | 1e7aB-4c0eA:2.3 | 1e7aB-4c0eA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fs3 | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADPH] FABI (Staphylococcusaureus) |
PF13561(adh_short_C2) | 5 | LEU A 208ILE A 207ASN A 205VAL A 201GLY A 202 | None0WE A 302 ( 4.8A)None0WE A 302 ( 4.4A)None | 1.02A | 1e7aB-4fs3A:undetectable | 1e7aB-4fs3A:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g9b | BETA-PHOSPHOGLUCOMUTASE (Escherichiacoli) |
PF13419(HAD_2) | 5 | ILE A 170LEU A 125VAL A 112GLY A 113LEU A 102 | None | 0.81A | 1e7aB-4g9bA:undetectable | 1e7aB-4g9bA:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4htl | BETA-GLUCOSIDEKINASE (Listeriamonocytogenes) |
PF00480(ROK) | 5 | LEU A 171ILE A 132PHE A 250LEU A 254GLY A 241 | None | 1.10A | 1e7aB-4htlA:undetectable | 1e7aB-4htlA:18.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ijm | CIRCADIAN CLOCKPROTEIN KINASE KAIC (Synechococcuselongatus) |
PF06745(ATPase) | 5 | LEU A 440ILE A 453PHE A 278LEU A 411VAL A 267 | None | 1.14A | 1e7aB-4ijmA:undetectable | 1e7aB-4ijmA:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j9u | TRK SYSTEM POTASSIUMUPTAKE PROTEIN TRKH (Vibrioparahaemolyticus) |
PF02386(TrkH) | 5 | LEU A 13ILE A 9LEU A 145VAL A 152GLY A 69 | None | 1.26A | 1e7aB-4j9uA:undetectable | 1e7aB-4j9uA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jc8 | HOPS COMPONENT VPS33 (Chaetomiumthermophilum) |
PF00995(Sec1) | 5 | ILE A 35PHE A 142VAL A 47GLY A 44LEU A 20 | None | 1.21A | 1e7aB-4jc8A:undetectable | 1e7aB-4jc8A:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kca | ENDO-1,5-ALPHA-L-ARABINANASE (Bos taurus) |
PF00085(Thioredoxin)PF04616(Glyco_hydro_43)PF16369(GH43_C) | 5 | ASN A 628PHE A 555VAL A 451GLY A 450LEU A 625 | NoneNoneNoneNoneIOD A 708 ( 4.7A) | 1.15A | 1e7aB-4kcaA:undetectable | 1e7aB-4kcaA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lp2 | HTH-TYPETRANSCRIPTIONALREGULATOR CYSB (Salmonellaenterica) |
PF03466(LysR_substrate) | 5 | ILE B 259LEU B 207VAL B 240GLY B 241LEU B 189 | None | 1.16A | 1e7aB-4lp2B:undetectable | 1e7aB-4lp2B:18.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m4d | LIPOPOLYSACCHARIDE-BINDING PROTEIN (Mus musculus) |
PF01273(LBP_BPI_CETP)PF02886(LBP_BPI_CETP_C) | 5 | LEU A 339ILE A 364PHE A 419VAL A 409LEU A 428 | None | 1.19A | 1e7aB-4m4dA:undetectable | 1e7aB-4m4dA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nvt | TRIOSEPHOSPHATEISOMERASE (Brucellamelitensis) |
PF00121(TIM) | 5 | LEU A 32ILE A 28LEU A 8VAL A 234GLY A 11 | None | 1.20A | 1e7aB-4nvtA:undetectable | 1e7aB-4nvtA:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o27 | CALCIUM-BINDINGPROTEIN 39 (Homo sapiens) |
PF08569(Mo25) | 5 | LEU A 54ILE A 53LEU A 83VAL A 16LEU A 74 | None | 1.03A | 1e7aB-4o27A:undetectable | 1e7aB-4o27A:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o7i | 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE,PUTATIVE (Entamoebahistolytica) |
PF00459(Inositol_P) | 5 | PHE A 126LEU A 29ARG A 129VAL A 44GLY A 45 | None | 1.01A | 1e7aB-4o7iA:undetectable | 1e7aB-4o7iA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ono | BETA-2-MICROGLOBULIN/T-CELL SURFACEGLYCOPROTEINCD1C/T-CELL SURFACEGLYCOPROTEIN CD1BCHIMERIC PROTEIN (Homo sapiens) |
PF07654(C1-set)PF16497(MHC_I_3) | 5 | LEU A 178ILE A 162PHE A 125LEU A 289GLY A 145 | NonePMK A 401 ( 3.3A)PMK A 401 ( 4.2A)NonePMK A 401 (-3.1A) | 1.06A | 1e7aB-4onoA:undetectable | 1e7aB-4onoA:20.07 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 8 | LEU A 387ASN A 391PHE A 403LEU A 407ARG A 410VAL A 433GLY A 434LEU A 453 | NPS A 601 ( 4.7A)NPS A 601 (-4.3A)NoneNPS A 601 ( 4.9A)NPS A 601 (-4.5A)NoneNoneNPS A 601 (-4.7A) | 0.69A | 1e7aB-4po0A:49.0 | 1e7aB-4po0A:74.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pxb | UREIDOGLYCOLATEHYDROLASE (Arabidopsisthaliana) |
PF01546(Peptidase_M20) | 5 | LEU A 179ARG A 97VAL A 151GLY A 150LEU A 73 | NoneNoneNone MN A 501 ( 4.0A)None | 1.14A | 1e7aB-4pxbA:undetectable | 1e7aB-4pxbA:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u49 | PECTATE LYASE (Pectobacteriumcarotovorum) |
PF03211(Pectate_lyase) | 5 | LEU A 246ILE A 280LEU A 269VAL A 311LEU A 299 | None | 1.07A | 1e7aB-4u49A:undetectable | 1e7aB-4u49A:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y0w | YEAZ (Pseudomonasaeruginosa) |
PF00814(Peptidase_M22) | 5 | LEU A 5ILE A 60LEU A 40GLY A 81LEU A 54 | None | 1.21A | 1e7aB-4y0wA:undetectable | 1e7aB-4y0wA:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a6b | N-ACETYL-BETA-D-GLUCOSAMINIDASE (Streptococcuspneumoniae) |
PF00728(Glyco_hydro_20) | 5 | ILE D 576ARG D 568VAL D 504GLY D 505LEU D 528 | None | 1.10A | 1e7aB-5a6bD:undetectable | 1e7aB-5a6bD:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bwi | GLYCOSIDE HYDROLASEFAMILY 79 (Burkholderiapseudomallei) |
PF12891(Glyco_hydro_44) | 5 | LEU A 335ILE A 26LEU A 237VAL A 292GLY A 291 | None | 1.19A | 1e7aB-5bwiA:undetectable | 1e7aB-5bwiA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c9j | T-CELL SURFACEGLYCOPROTEINCD1C,T-CELL SURFACEGLYCOPROTEIN CD1B (Homo sapiens) |
PF07654(C1-set)PF16497(MHC_I_3) | 5 | LEU A 66ILE A 50PHE A 13LEU A 177GLY A 33 | NoneSTE A 303 ( 3.9A)STE A 303 ( 4.8A)NoneSTE A 303 ( 4.2A) | 1.20A | 1e7aB-5c9jA:undetectable | 1e7aB-5c9jA:17.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cfv | MALTOSE-BINDINGPERIPLASMICPROTEIN,MALTOSE-BINDING PERIPLASMICPROTEIN,PILA FUSIONPROTEIN (Acinetobacternosocomialis;Escherichiacoli) |
PF00114(Pilin)PF01547(SBP_bac_1) | 5 | ILE A 9LEU A 262VAL A 293GLY A 16LEU A 284 | None | 1.25A | 1e7aB-5cfvA:undetectable | 1e7aB-5cfvA:22.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 7 | LEU A 386ASN A 390PHE A 402LEU A 406ARG A 409VAL A 432GLY A 433 | None | 0.79A | 1e7aB-5dqfA:49.7 | 1e7aB-5dqfA:76.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 7 | LEU A 386ASN A 390PHE A 402LEU A 406VAL A 432GLY A 433LEU A 452 | None | 0.67A | 1e7aB-5dqfA:49.7 | 1e7aB-5dqfA:76.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e7p | CELL DIVISIONCONTROL PROTEINCDC48 (Mycolicibacteriumsmegmatis) |
PF00004(AAA)PF02359(CDC48_N) | 5 | LEU A 352ILE A 348VAL A 297GLY A 298LEU A 292 | None | 1.25A | 1e7aB-5e7pA:undetectable | 1e7aB-5e7pA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eog | PROTEIN MAB-21-LIKE1 (Homo sapiens) |
PF03281(Mab-21) | 5 | LEU A 257ILE A 253LEU A 350GLY A 297LEU A 356 | None | 1.19A | 1e7aB-5eogA:undetectable | 1e7aB-5eogA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5far | 7,8-DIHYDRONEOPTERINALDOLASE (Bacillus cereus) |
PF02152(FolB) | 5 | LEU A 32ILE A 95PHE A 11VAL A 63LEU A 59 | None | 1.24A | 1e7aB-5farA:undetectable | 1e7aB-5farA:12.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 8 | LEU A 387ASN A 391PHE A 403LEU A 407ARG A 410VAL A 433GLY A 434LEU A 453 | None | 0.73A | 1e7aB-5ghkA:46.5 | 1e7aB-5ghkA:79.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i4q | CONTACT-DEPENDENTINHIBITOR A (Escherichiacoli) |
no annotation | 5 | LEU A 235LEU A 195ARG A 200VAL A 246GLY A 247 | None | 1.20A | 1e7aB-5i4qA:undetectable | 1e7aB-5i4qA:9.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ii5 | MALTOSE-BINDINGPERIPLASMICPROTEIN,VITELLINEENVELOPE SPERM LYSINRECEPTOR (Escherichiacoli;Haliotisrufescens) |
PF11386(VERL)PF13416(SBP_bac_8) | 5 | ILE A3676LEU A3929VAL A3960GLY A3683LEU A3951 | None | 1.25A | 1e7aB-5ii5A:0.5 | 1e7aB-5ii5A:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kre | LYSOPHOSPHOLIPASE-LIKE PROTEIN 1 (Homo sapiens) |
PF02230(Abhydrolase_2) | 5 | LEU A 49ILE A 41LEU A 119GLY A 122LEU A 221 | None | 1.12A | 1e7aB-5kreA:undetectable | 1e7aB-5kreA:17.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqi | PROTEIN TIMELESSHOMOLOG,PROTEINTIMELESS HOMOLOG (Homo sapiens) |
PF04821(TIMELESS) | 5 | LEU A 162ILE A 159VAL A 132GLY A 131LEU A 69 | None | 0.99A | 1e7aB-5mqiA:undetectable | 1e7aB-5mqiA:22.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 6 | ASN A 390PHE A 402LEU A 406ARG A 409GLY A 433LEU A 452 | None | 0.79A | 1e7aB-5oriA:49.2 | 1e7aB-5oriA:74.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 7 | LEU A 386ILE A 387ASN A 390PHE A 402LEU A 406GLY A 433LEU A 452 | None | 0.85A | 1e7aB-5oriA:49.2 | 1e7aB-5oriA:74.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 6 | LEU A 386ILE A 387LEU A 406VAL A 432GLY A 433LEU A 452 | None | 0.87A | 1e7aB-5oriA:49.2 | 1e7aB-5oriA:74.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5sy1 | STRA6 (Danio rerio) |
PF14752(RBP_receptor) | 5 | LEU A 134ILE A 44PHE A 113LEU A 111GLY A 38 | None | 1.16A | 1e7aB-5sy1A:undetectable | 1e7aB-5sy1A:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u81 | ACID CERAMIDASEISOFORM B (Heterocephalusglaber) |
no annotation | 5 | LEU A 236ILE A 240PHE A 108GLY A 106LEU A 101 | None | 1.10A | 1e7aB-5u81A:undetectable | 1e7aB-5u81A:8.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uw2 | PROBABLEPHOSPHOLIPID ABCTRANSPORTER-BINDINGPROTEIN MLAD (Escherichiacoli) |
PF02470(MlaD) | 5 | LEU A 128ILE A 93VAL A 58GLY A 66LEU A 99 | None | 1.02A | 1e7aB-5uw2A:undetectable | 1e7aB-5uw2A:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uw8 | PROBABLEPHOSPHOLIPID ABCTRANSPORTER-BINDINGPROTEIN MLAD (Escherichiacoli) |
PF02470(MlaD) | 5 | LEU A 128ILE A 93VAL A 58GLY A 66LEU A 99 | None | 1.03A | 1e7aB-5uw8A:undetectable | 1e7aB-5uw8A:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ywp | JEV E PROTEIN (Japaneseencephalitisvirus) |
no annotation | 5 | LEU A 180PHE A 167LEU A 188GLY A 140LEU A 41 | None | 1.26A | 1e7aB-5ywpA:undetectable | 1e7aB-5ywpA:9.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 7 | LEU A 387ASN A 391LEU A 407ARG A 410VAL A 433GLY A 434LEU A 453 | None | 0.83A | 1e7aB-5yxeA:47.4 | 1e7aB-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 7 | LEU A 387ASN A 391PHE A 403LEU A 407ARG A 410GLY A 434LEU A 453 | None | 0.75A | 1e7aB-5yxeA:47.4 | 1e7aB-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfw | MBH13 NADHDEHYDROGENASESUBUNIT (Pyrococcusfuriosus) |
no annotation | 5 | LEU M 227ILE M 230PHE M 68VAL M 118GLY M 117 | None | 0.89A | 1e7aB-6cfwM:undetectable | 1e7aB-6cfwM:8.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fik | POLYKETIDE SYNTHASE (Cercosporanicotianae) |
no annotation | 5 | LEU A 992LEU A1233VAL A1001GLY A1000LEU A1193 | None | 1.21A | 1e7aB-6fikA:undetectable | 1e7aB-6fikA:9.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gpc | - (-) |
no annotation | 5 | LEU A 46ILE A 42ARG A 8VAL A 108LEU A 115 | None | 1.19A | 1e7aB-6gpcA:undetectable | 1e7aB-6gpcA:undetectable |