SIMILAR PATTERNS OF AMINO ACIDS FOR 1E7A_B_PFLB4001

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0j TRYPSIN

(Salmo salar)
PF00089
(Trypsin)
5 LEU A 163
ILE A 162
VAL A 199
GLY A 211
LEU A 160
None
0.98A 1e7aB-1a0jA:
undetectable
1e7aB-1a0jA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dj2 ADENYLOSUCCINATE
SYNTHETASE


(Arabidopsis
thaliana)
PF00709
(Adenylsucc_synt)
5 LEU A 347
ILE A 428
LEU A 361
VAL A 424
LEU A 333
None
1.17A 1e7aB-1dj2A:
0.0
1e7aB-1dj2A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e0c SULFURTRANSFERASE

(Azotobacter
vinelandii)
PF00581
(Rhodanese)
5 ILE A  99
PHE A  73
LEU A  72
VAL A  28
LEU A  30
None
1.12A 1e7aB-1e0cA:
undetectable
1e7aB-1e0cA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fzq ADP-RIBOSYLATION
FACTOR-LIKE PROTEIN
3


(Mus musculus)
PF00025
(Arf)
5 ILE A  89
LEU A  10
VAL A 166
GLY A 169
LEU A  37
None
1.08A 1e7aB-1fzqA:
undetectable
1e7aB-1fzqA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h9h TRYPSIN

(Sus scrofa)
PF00089
(Trypsin)
5 LEU E 105
ILE E 106
LEU E 209
VAL E  31
GLY E  43
None
1.25A 1e7aB-1h9hE:
undetectable
1e7aB-1h9hE:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jik TYROSYL-TRNA
SYNTHETASE


(Staphylococcus
aureus)
PF00579
(tRNA-synt_1b)
5 LEU A   9
ILE A  15
LEU A  35
GLY A 218
LEU A  28
None
1.16A 1e7aB-1jikA:
undetectable
1e7aB-1jikA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mb0 CELL DIVISION
RESPONSE REGULATOR
DIVK


(Caulobacter
vibrioides)
PF00072
(Response_reg)
5 LEU A   6
ILE A  50
VAL A  64
GLY A  61
LEU A  39
None
1.26A 1e7aB-1mb0A:
undetectable
1e7aB-1mb0A:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mbq TRYPSIN

(Oncorhynchus
keta)
PF00089
(Trypsin)
5 LEU A 105
ILE A 106
LEU A 209
VAL A  31
GLY A  44
None
1.25A 1e7aB-1mbqA:
undetectable
1e7aB-1mbqA:
16.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens)
PF00273
(Serum_albumin)
8 LEU A 387
ILE A 388
ASN A 391
PHE A 403
LEU A 407
ARG A 410
GLY A 434
LEU A 453
None
0.63A 1e7aB-1tf0A:
47.1
1e7aB-1tf0A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens)
PF00273
(Serum_albumin)
6 LEU A 387
ILE A 388
LEU A 407
VAL A 433
GLY A 434
LEU A 453
None
0.69A 1e7aB-1tf0A:
47.1
1e7aB-1tf0A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vhi EPSTEIN BARR VIRUS
NUCLEAR ANTIGEN-1


(Human
gammaherpesvirus
4)
PF02905
(EBV-NA1)
5 LEU A 485
PHE A 562
LEU A 533
VAL A 507
LEU A 575
None
1.17A 1e7aB-1vhiA:
undetectable
1e7aB-1vhiA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y4c MALTOSE BINDING
PROTEIN FUSED WITH
DESIGNED HELICAL
PROTEIN


(Escherichia
coli)
PF13416
(SBP_bac_8)
5 ILE A   9
LEU A 262
VAL A 293
GLY A  16
LEU A 284
None
1.25A 1e7aB-1y4cA:
undetectable
1e7aB-1y4cA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y9a NADP-DEPENDENT
ALCOHOL
DEHYDROGENASE


(Entamoeba
histolytica)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
5 LEU A 189
ILE A 164
ARG A 301
VAL A 240
GLY A 263
None
1.24A 1e7aB-1y9aA:
undetectable
1e7aB-1y9aA:
20.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ysx SERUM ALBUMIN

(Homo sapiens)
PF00273
(Serum_albumin)
5 LEU A 387
ILE A 388
ASN A 391
PHE A 403
LEU A 407
None
4EB  A1000 ( 4.6A)
4EB  A1000 (-3.5A)
4EB  A1000 ( 4.1A)
4EB  A1000 (-4.5A)
0.70A 1e7aB-1ysxA:
6.0
1e7aB-1ysxA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aw5 NADP-DEPENDENT MALIC
ENZYME


(Homo sapiens)
PF00390
(malic)
PF03949
(Malic_M)
5 ILE A 382
LEU A 376
VAL A 334
GLY A 301
LEU A 364
None
1.12A 1e7aB-2aw5A:
undetectable
1e7aB-2aw5A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bhv COMB10

(Helicobacter
pylori)
PF03743
(TrbI)
5 ILE A 354
LEU A 233
VAL A 194
GLY A 220
LEU A 182
None
1.19A 1e7aB-2bhvA:
undetectable
1e7aB-2bhvA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eek TRYPSIN-1

(Gadus morhua)
PF00089
(Trypsin)
5 LEU A 105
ILE A 106
LEU A 209
VAL A  31
GLY A  44
None
1.26A 1e7aB-2eekA:
undetectable
1e7aB-2eekA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eek TRYPSIN-1

(Gadus morhua)
PF00089
(Trypsin)
5 LEU A 163
ILE A 162
VAL A 199
GLY A 211
LEU A 160
None
0.99A 1e7aB-2eekA:
undetectable
1e7aB-2eekA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2elc ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE


(Thermus
thermophilus)
PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
5 LEU A  74
ILE A  76
LEU A 205
VAL A 215
GLY A 191
None
1.13A 1e7aB-2elcA:
undetectable
1e7aB-2elcA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ell ACIDIC LEUCINE-RICH
NUCLEAR
PHOSPHOPROTEIN 32
FAMILY MEMBER B


(Homo sapiens)
PF14580
(LRR_9)
5 LEU A  67
ILE A  41
VAL A  59
GLY A  60
LEU A  56
None
1.16A 1e7aB-2ellA:
undetectable
1e7aB-2ellA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mqw 26S PROTEASOME
REGULATORY SUBUNIT
RPN9


(Saccharomyces
cerevisiae)
no annotation 5 LEU A  11
ILE A  10
LEU A  41
VAL A  66
LEU A  61
None
1.24A 1e7aB-2mqwA:
undetectable
1e7aB-2mqwA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q03 UNCHARACTERIZED
PROTEIN


(Shewanella
denitrificans)
PF11528
(DUF3224)
5 LEU A  46
ILE A  10
PHE A 100
LEU A  85
LEU A 134
None
1.14A 1e7aB-2q03A:
undetectable
1e7aB-2q03A:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q2r GLUCOKINASE 1,
PUTATIVE


(Trypanosoma
cruzi)
PF02685
(Glucokinase)
5 LEU A 132
LEU A 304
VAL A 289
GLY A 290
LEU A 187
BGC  A1001 ( 4.8A)
None
None
None
None
1.12A 1e7aB-2q2rA:
1.7
1e7aB-2q2rA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vhl N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE


(Bacillus
subtilis)
PF01979
(Amidohydro_1)
5 LEU A 379
ILE A 381
VAL A  24
GLY A  25
LEU A  55
None
1.14A 1e7aB-2vhlA:
undetectable
1e7aB-2vhlA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x9x CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN


(Streptococcus
pneumoniae)
PF16569
(GramPos_pilinBB)
PF16570
(GramPos_pilinD3)
5 ILE A 535
ASN A 538
PHE A 541
LEU A 478
GLY A 567
None
0.90A 1e7aB-2x9xA:
3.4
1e7aB-2x9xA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xgo XCOGT

(Xanthomonas
campestris)
PF13432
(TPR_16)
PF13844
(Glyco_transf_41)
5 LEU A 328
LEU A 231
VAL A 208
GLY A 209
LEU A 556
None
1.22A 1e7aB-2xgoA:
undetectable
1e7aB-2xgoA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yys PROLINE
IMINOPEPTIDASE-RELAT
ED PROTEIN


(Thermus
thermophilus)
PF12697
(Abhydrolase_6)
5 LEU A  81
LEU A  69
VAL A  10
GLY A  11
LEU A  15
None
1.19A 1e7aB-2yysA:
undetectable
1e7aB-2yysA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aib GLUCOSYLTRANSFERASE-
SI


(Streptococcus
mutans)
PF02324
(Glyco_hydro_70)
5 ILE A 775
LEU A 646
VAL A 818
GLY A 817
LEU A 683
None
1.13A 1e7aB-3aibA:
undetectable
1e7aB-3aibA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b8y ENDO-PECTATE LYASE

(Dickeya
chrysanthemi)
PF03211
(Pectate_lyase)
5 LEU A 243
ILE A 277
LEU A 266
VAL A 308
LEU A 296
None
1.09A 1e7aB-3b8yA:
undetectable
1e7aB-3b8yA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b90 ENDO-PECTATE LYASE

(Dickeya
chrysanthemi)
PF03211
(Pectate_lyase)
5 LEU A 243
ILE A 277
LEU A 266
VAL A 308
LEU A 296
None
1.12A 1e7aB-3b90A:
undetectable
1e7aB-3b90A:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9g IAG-NUCLEOSIDE
HYDROLASE


(Trypanosoma
vivax)
PF01156
(IU_nuc_hydro)
5 LEU A  96
ILE A  95
LEU A  13
VAL A 238
GLY A 239
None
1.22A 1e7aB-3b9gA:
undetectable
1e7aB-3b9gA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d00 TUNGSTEN
FORMYLMETHANOFURAN
DEHYDROGENASE
SUBUNIT E


(Syntrophus
aciditrophicus)
PF02663
(FmdE)
5 LEU A 130
ILE A 134
PHE A  84
VAL A  29
GLY A  32
None
1.26A 1e7aB-3d00A:
undetectable
1e7aB-3d00A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dc7 PUTATIVE
UNCHARACTERIZED
PROTEIN LP_3323


(Lactobacillus
plantarum)
PF13472
(Lipase_GDSL_2)
5 LEU A  46
ILE A  45
LEU A 180
VAL A 211
GLY A 208
None
1.22A 1e7aB-3dc7A:
undetectable
1e7aB-3dc7A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633


(Methanosarcina
mazei)
PF13649
(Methyltransf_25)
5 ILE A  95
LEU A 128
ARG A 131
GLY A  50
LEU A  47
None
0.95A 1e7aB-3dtnA:
undetectable
1e7aB-3dtnA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fpc NADP-DEPENDENT
ALCOHOL
DEHYDROGENASE


(Entamoeba
histolytica;
Thermoanaerobacter
brockii)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
5 LEU A 189
ILE A 164
ARG A 301
VAL A 240
GLY A 263
None
1.23A 1e7aB-3fpcA:
undetectable
1e7aB-3fpcA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gg2 SUGAR DEHYDROGENASE,
UDP-GLUCOSE/GDP-MANN
OSE DEHYDROGENASE
FAMILY


(Porphyromonas
gingivalis)
PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N)
5 LEU A 423
ILE A 420
LEU A 465
VAL A 468
GLY A 401
None
1.26A 1e7aB-3gg2A:
undetectable
1e7aB-3gg2A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN


(Legionella
pneumophila)
no annotation 5 LEU A 162
ILE A 161
LEU A 187
GLY A 151
LEU A 174
None
1.14A 1e7aB-3gozA:
undetectable
1e7aB-3gozA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iyl VP1

(Aquareovirus C)
PF06016
(Reovirus_L2)
5 ILE W 131
LEU W  30
VAL W 117
GLY W 119
LEU W 138
None
1.10A 1e7aB-3iylW:
undetectable
1e7aB-3iylW:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k1t GLUTAMATE--CYSTEINE
LIGASE GSHA


(Methylobacillus
flagellatus)
PF08886
(GshA)
5 LEU A 179
ILE A 183
LEU A 163
GLY A 189
LEU A 194
None
CL  A 436 (-4.3A)
None
SO4  A 435 (-3.5A)
None
1.04A 1e7aB-3k1tA:
undetectable
1e7aB-3k1tA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mop INTERLEUKIN-1
RECEPTOR-ASSOCIATED
KINASE 4


(Homo sapiens)
no annotation 5 LEU G  35
ILE G  39
LEU G 100
VAL G  11
LEU G  71
None
1.19A 1e7aB-3mopG:
undetectable
1e7aB-3mopG:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n5m ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE


(Bacillus
anthracis)
PF00202
(Aminotran_3)
5 LEU A 355
ILE A 359
LEU A 406
VAL A 397
LEU A 422
None
1.19A 1e7aB-3n5mA:
undetectable
1e7aB-3n5mA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oz7 PHOSPHOGLYCERATE
KINASE


(Plasmodium
falciparum)
PF00162
(PGK)
5 ILE A 369
PHE A 165
LEU A 407
GLY A 394
LEU A 402
None
1.24A 1e7aB-3oz7A:
undetectable
1e7aB-3oz7A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qe7 URACIL PERMEASE

(Escherichia
coli)
PF00860
(Xan_ur_permease)
5 LEU A 322
ILE A 326
LEU A  25
GLY A  30
LEU A  47
None
1.11A 1e7aB-3qe7A:
undetectable
1e7aB-3qe7A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qxz ENOYL-COA
HYDRATASE/ISOMERASE


(Mycobacteroides
abscessus)
PF00378
(ECH_1)
5 LEU A 158
ILE A 129
LEU A 121
GLY A 109
LEU A 114
None
1.12A 1e7aB-3qxzA:
undetectable
1e7aB-3qxzA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I


(Burkholderia
lata)
PF00117
(GATase)
PF00425
(Chorismate_bind)
5 LEU A 512
ILE A 516
VAL A 586
GLY A 602
LEU A 536
None
1.12A 1e7aB-3r75A:
undetectable
1e7aB-3r75A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3re1 UROPORPHYRINOGEN-III
SYNTHETASE


(Pseudomonas
syringae group
genomosp. 3)
PF02602
(HEM4)
5 ILE A 233
LEU A   8
ARG A  10
GLY A 185
LEU A 247
None
1.15A 1e7aB-3re1A:
undetectable
1e7aB-3re1A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rr1 PUTATIVE
D-GALACTONATE
DEHYDRATASE


(Ralstonia
pickettii)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
6 LEU A 182
ILE A 208
ARG A 166
VAL A 188
GLY A 186
LEU A 196
None
1.41A 1e7aB-3rr1A:
undetectable
1e7aB-3rr1A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tbh O-ACETYL SERINE
SULFHYDRYLASE


(Leishmania
donovani)
PF00291
(PALP)
5 LEU A 244
ILE A 245
VAL A 185
GLY A 184
LEU A 240
None
None
LLP  A  51 ( 4.2A)
None
None
1.10A 1e7aB-3tbhA:
undetectable
1e7aB-3tbhA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqs RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A


(Coxiella
burnetii)
PF00398
(RrnaAD)
5 LEU A  21
ILE A  24
VAL A 104
GLY A 105
LEU A  50
None
1.25A 1e7aB-3tqsA:
undetectable
1e7aB-3tqsA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tsr RIBONUCLEASE
INHIBITOR


(Mus musculus)
PF13516
(LRR_6)
5 ASN E 403
LEU E 385
VAL E 410
GLY E 409
LEU E 429
None
1.24A 1e7aB-3tsrE:
undetectable
1e7aB-3tsrE:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vla EDGP

(Daucus carota)
PF14541
(TAXi_C)
PF14543
(TAXi_N)
5 LEU A 332
ILE A 330
VAL A 361
GLY A 360
LEU A 279
None
1.10A 1e7aB-3vlaA:
undetectable
1e7aB-3vlaA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vvj OVALBUMIN

(Dromaius
novaehollandiae)
PF00079
(Serpin)
5 ILE A 122
LEU A 322
VAL A  42
GLY A  45
LEU A 175
None
1.10A 1e7aB-3vvjA:
undetectable
1e7aB-3vvjA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wai MALTOSE-BINDING
PERIPLASMIC PROTEIN,
TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE


(Archaeoglobus
fulgidus;
Escherichia
coli)
PF13416
(SBP_bac_8)
5 ILE A   9
LEU A 262
VAL A 293
GLY A  16
LEU A 284
None
1.25A 1e7aB-3waiA:
undetectable
1e7aB-3waiA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zcw KINESIN-LIKE PROTEIN
KIF11


(Homo sapiens)
PF00225
(Kinesin)
5 ILE A  19
LEU A 316
VAL A 298
GLY A 296
LEU A 324
None
None
None
4A2  A1366 (-3.4A)
None
1.26A 1e7aB-3zcwA:
undetectable
1e7aB-3zcwA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zog FMN-BINDING PROTEIN

(Pyrococcus
horikoshii)
PF01613
(Flavin_Reduct)
5 LEU A  14
ILE A  15
LEU A  93
VAL A 101
GLY A  18
None
1.24A 1e7aB-3zogA:
undetectable
1e7aB-3zogA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c0e NOT1

(Chaetomium
thermophilum)
PF04054
(Not1)
5 LEU A2007
LEU A1999
VAL A2016
GLY A2015
LEU A2082
None
1.21A 1e7aB-4c0eA:
2.3
1e7aB-4c0eA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fs3 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADPH] FABI


(Staphylococcus
aureus)
PF13561
(adh_short_C2)
5 LEU A 208
ILE A 207
ASN A 205
VAL A 201
GLY A 202
None
0WE  A 302 ( 4.8A)
None
0WE  A 302 ( 4.4A)
None
1.02A 1e7aB-4fs3A:
undetectable
1e7aB-4fs3A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g9b BETA-PHOSPHOGLUCOMUT
ASE


(Escherichia
coli)
PF13419
(HAD_2)
5 ILE A 170
LEU A 125
VAL A 112
GLY A 113
LEU A 102
None
0.81A 1e7aB-4g9bA:
undetectable
1e7aB-4g9bA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4htl BETA-GLUCOSIDE
KINASE


(Listeria
monocytogenes)
PF00480
(ROK)
5 LEU A 171
ILE A 132
PHE A 250
LEU A 254
GLY A 241
None
1.10A 1e7aB-4htlA:
undetectable
1e7aB-4htlA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ijm CIRCADIAN CLOCK
PROTEIN KINASE KAIC


(Synechococcus
elongatus)
PF06745
(ATPase)
5 LEU A 440
ILE A 453
PHE A 278
LEU A 411
VAL A 267
None
1.14A 1e7aB-4ijmA:
undetectable
1e7aB-4ijmA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH


(Vibrio
parahaemolyticus)
PF02386
(TrkH)
5 LEU A  13
ILE A   9
LEU A 145
VAL A 152
GLY A  69
None
1.26A 1e7aB-4j9uA:
undetectable
1e7aB-4j9uA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jc8 HOPS COMPONENT VPS33

(Chaetomium
thermophilum)
PF00995
(Sec1)
5 ILE A  35
PHE A 142
VAL A  47
GLY A  44
LEU A  20
None
1.21A 1e7aB-4jc8A:
undetectable
1e7aB-4jc8A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kca ENDO-1,5-ALPHA-L-ARA
BINANASE


(Bos taurus)
PF00085
(Thioredoxin)
PF04616
(Glyco_hydro_43)
PF16369
(GH43_C)
5 ASN A 628
PHE A 555
VAL A 451
GLY A 450
LEU A 625
None
None
None
None
IOD  A 708 ( 4.7A)
1.15A 1e7aB-4kcaA:
undetectable
1e7aB-4kcaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lp2 HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CYSB


(Salmonella
enterica)
PF03466
(LysR_substrate)
5 ILE B 259
LEU B 207
VAL B 240
GLY B 241
LEU B 189
None
1.16A 1e7aB-4lp2B:
undetectable
1e7aB-4lp2B:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m4d LIPOPOLYSACCHARIDE-B
INDING PROTEIN


(Mus musculus)
PF01273
(LBP_BPI_CETP)
PF02886
(LBP_BPI_CETP_C)
5 LEU A 339
ILE A 364
PHE A 419
VAL A 409
LEU A 428
None
1.19A 1e7aB-4m4dA:
undetectable
1e7aB-4m4dA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nvt TRIOSEPHOSPHATE
ISOMERASE


(Brucella
melitensis)
PF00121
(TIM)
5 LEU A  32
ILE A  28
LEU A   8
VAL A 234
GLY A  11
None
1.20A 1e7aB-4nvtA:
undetectable
1e7aB-4nvtA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o27 CALCIUM-BINDING
PROTEIN 39


(Homo sapiens)
PF08569
(Mo25)
5 LEU A  54
ILE A  53
LEU A  83
VAL A  16
LEU A  74
None
1.03A 1e7aB-4o27A:
undetectable
1e7aB-4o27A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o7i 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE


(Entamoeba
histolytica)
PF00459
(Inositol_P)
5 PHE A 126
LEU A  29
ARG A 129
VAL A  44
GLY A  45
None
1.01A 1e7aB-4o7iA:
undetectable
1e7aB-4o7iA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ono BETA-2-MICROGLOBULIN
/T-CELL SURFACE
GLYCOPROTEIN
CD1C/T-CELL SURFACE
GLYCOPROTEIN CD1B
CHIMERIC PROTEIN


(Homo sapiens)
PF07654
(C1-set)
PF16497
(MHC_I_3)
5 LEU A 178
ILE A 162
PHE A 125
LEU A 289
GLY A 145
None
PMK  A 401 ( 3.3A)
PMK  A 401 ( 4.2A)
None
PMK  A 401 (-3.1A)
1.06A 1e7aB-4onoA:
undetectable
1e7aB-4onoA:
20.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4po0 SERUM ALBUMIN

(Oryctolagus
cuniculus)
PF00273
(Serum_albumin)
8 LEU A 387
ASN A 391
PHE A 403
LEU A 407
ARG A 410
VAL A 433
GLY A 434
LEU A 453
NPS  A 601 ( 4.7A)
NPS  A 601 (-4.3A)
None
NPS  A 601 ( 4.9A)
NPS  A 601 (-4.5A)
None
None
NPS  A 601 (-4.7A)
0.69A 1e7aB-4po0A:
49.0
1e7aB-4po0A:
74.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pxb UREIDOGLYCOLATE
HYDROLASE


(Arabidopsis
thaliana)
PF01546
(Peptidase_M20)
5 LEU A 179
ARG A  97
VAL A 151
GLY A 150
LEU A  73
None
None
None
MN  A 501 ( 4.0A)
None
1.14A 1e7aB-4pxbA:
undetectable
1e7aB-4pxbA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u49 PECTATE LYASE

(Pectobacterium
carotovorum)
PF03211
(Pectate_lyase)
5 LEU A 246
ILE A 280
LEU A 269
VAL A 311
LEU A 299
None
1.07A 1e7aB-4u49A:
undetectable
1e7aB-4u49A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y0w YEAZ

(Pseudomonas
aeruginosa)
PF00814
(Peptidase_M22)
5 LEU A   5
ILE A  60
LEU A  40
GLY A  81
LEU A  54
None
1.21A 1e7aB-4y0wA:
undetectable
1e7aB-4y0wA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a6b N-ACETYL-BETA-D-GLUC
OSAMINIDASE


(Streptococcus
pneumoniae)
PF00728
(Glyco_hydro_20)
5 ILE D 576
ARG D 568
VAL D 504
GLY D 505
LEU D 528
None
1.10A 1e7aB-5a6bD:
undetectable
1e7aB-5a6bD:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bwi GLYCOSIDE HYDROLASE
FAMILY 79


(Burkholderia
pseudomallei)
PF12891
(Glyco_hydro_44)
5 LEU A 335
ILE A  26
LEU A 237
VAL A 292
GLY A 291
None
1.19A 1e7aB-5bwiA:
undetectable
1e7aB-5bwiA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c9j T-CELL SURFACE
GLYCOPROTEIN
CD1C,T-CELL SURFACE
GLYCOPROTEIN CD1B


(Homo sapiens)
PF07654
(C1-set)
PF16497
(MHC_I_3)
5 LEU A  66
ILE A  50
PHE A  13
LEU A 177
GLY A  33
None
STE  A 303 ( 3.9A)
STE  A 303 ( 4.8A)
None
STE  A 303 ( 4.2A)
1.20A 1e7aB-5c9jA:
undetectable
1e7aB-5c9jA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cfv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MALTOSE-BIND
ING PERIPLASMIC
PROTEIN,PILA FUSION
PROTEIN


(Acinetobacter
nosocomialis;
Escherichia
coli)
PF00114
(Pilin)
PF01547
(SBP_bac_1)
5 ILE A   9
LEU A 262
VAL A 293
GLY A  16
LEU A 284
None
1.25A 1e7aB-5cfvA:
undetectable
1e7aB-5cfvA:
22.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dqf SERUM ALBUMIN

(Equus caballus)
PF00273
(Serum_albumin)
7 LEU A 386
ASN A 390
PHE A 402
LEU A 406
ARG A 409
VAL A 432
GLY A 433
None
0.79A 1e7aB-5dqfA:
49.7
1e7aB-5dqfA:
76.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dqf SERUM ALBUMIN

(Equus caballus)
PF00273
(Serum_albumin)
7 LEU A 386
ASN A 390
PHE A 402
LEU A 406
VAL A 432
GLY A 433
LEU A 452
None
0.67A 1e7aB-5dqfA:
49.7
1e7aB-5dqfA:
76.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e7p CELL DIVISION
CONTROL PROTEIN
CDC48


(Mycolicibacterium
smegmatis)
PF00004
(AAA)
PF02359
(CDC48_N)
5 LEU A 352
ILE A 348
VAL A 297
GLY A 298
LEU A 292
None
1.25A 1e7aB-5e7pA:
undetectable
1e7aB-5e7pA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eog PROTEIN MAB-21-LIKE
1


(Homo sapiens)
PF03281
(Mab-21)
5 LEU A 257
ILE A 253
LEU A 350
GLY A 297
LEU A 356
None
1.19A 1e7aB-5eogA:
undetectable
1e7aB-5eogA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5far 7,8-DIHYDRONEOPTERIN
ALDOLASE


(Bacillus cereus)
PF02152
(FolB)
5 LEU A  32
ILE A  95
PHE A  11
VAL A  63
LEU A  59
None
1.24A 1e7aB-5farA:
undetectable
1e7aB-5farA:
12.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus)
PF00273
(Serum_albumin)
8 LEU A 387
ASN A 391
PHE A 403
LEU A 407
ARG A 410
VAL A 433
GLY A 434
LEU A 453
None
0.73A 1e7aB-5ghkA:
46.5
1e7aB-5ghkA:
79.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i4q CONTACT-DEPENDENT
INHIBITOR A


(Escherichia
coli)
no annotation 5 LEU A 235
LEU A 195
ARG A 200
VAL A 246
GLY A 247
None
1.20A 1e7aB-5i4qA:
undetectable
1e7aB-5i4qA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR


(Escherichia
coli;
Haliotis
rufescens)
PF11386
(VERL)
PF13416
(SBP_bac_8)
5 ILE A3676
LEU A3929
VAL A3960
GLY A3683
LEU A3951
None
1.25A 1e7aB-5ii5A:
0.5
1e7aB-5ii5A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kre LYSOPHOSPHOLIPASE-LI
KE PROTEIN 1


(Homo sapiens)
PF02230
(Abhydrolase_2)
5 LEU A  49
ILE A  41
LEU A 119
GLY A 122
LEU A 221
None
1.12A 1e7aB-5kreA:
undetectable
1e7aB-5kreA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqi PROTEIN TIMELESS
HOMOLOG,PROTEIN
TIMELESS HOMOLOG


(Homo sapiens)
PF04821
(TIMELESS)
5 LEU A 162
ILE A 159
VAL A 132
GLY A 131
LEU A  69
None
0.99A 1e7aB-5mqiA:
undetectable
1e7aB-5mqiA:
22.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ori ALBUMIN

(Capra hircus)
no annotation 6 ASN A 390
PHE A 402
LEU A 406
ARG A 409
GLY A 433
LEU A 452
None
0.79A 1e7aB-5oriA:
49.2
1e7aB-5oriA:
74.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ori ALBUMIN

(Capra hircus)
no annotation 7 LEU A 386
ILE A 387
ASN A 390
PHE A 402
LEU A 406
GLY A 433
LEU A 452
None
0.85A 1e7aB-5oriA:
49.2
1e7aB-5oriA:
74.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ori ALBUMIN

(Capra hircus)
no annotation 6 LEU A 386
ILE A 387
LEU A 406
VAL A 432
GLY A 433
LEU A 452
None
0.87A 1e7aB-5oriA:
49.2
1e7aB-5oriA:
74.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sy1 STRA6

(Danio rerio)
PF14752
(RBP_receptor)
5 LEU A 134
ILE A  44
PHE A 113
LEU A 111
GLY A  38
None
1.16A 1e7aB-5sy1A:
undetectable
1e7aB-5sy1A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u81 ACID CERAMIDASE
ISOFORM B


(Heterocephalus
glaber)
no annotation 5 LEU A 236
ILE A 240
PHE A 108
GLY A 106
LEU A 101
None
1.10A 1e7aB-5u81A:
undetectable
1e7aB-5u81A:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uw2 PROBABLE
PHOSPHOLIPID ABC
TRANSPORTER-BINDING
PROTEIN MLAD


(Escherichia
coli)
PF02470
(MlaD)
5 LEU A 128
ILE A  93
VAL A  58
GLY A  66
LEU A  99
None
1.02A 1e7aB-5uw2A:
undetectable
1e7aB-5uw2A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uw8 PROBABLE
PHOSPHOLIPID ABC
TRANSPORTER-BINDING
PROTEIN MLAD


(Escherichia
coli)
PF02470
(MlaD)
5 LEU A 128
ILE A  93
VAL A  58
GLY A  66
LEU A  99
None
1.03A 1e7aB-5uw8A:
undetectable
1e7aB-5uw8A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ywp JEV E PROTEIN

(Japanese
encephalitis
virus)
no annotation 5 LEU A 180
PHE A 167
LEU A 188
GLY A 140
LEU A  41
None
1.26A 1e7aB-5ywpA:
undetectable
1e7aB-5ywpA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yxe SERUM ALBUMIN

(Felis catus)
no annotation 7 LEU A 387
ASN A 391
LEU A 407
ARG A 410
VAL A 433
GLY A 434
LEU A 453
None
0.83A 1e7aB-5yxeA:
47.4
1e7aB-5yxeA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yxe SERUM ALBUMIN

(Felis catus)
no annotation 7 LEU A 387
ASN A 391
PHE A 403
LEU A 407
ARG A 410
GLY A 434
LEU A 453
None
0.75A 1e7aB-5yxeA:
47.4
1e7aB-5yxeA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfw MBH13 NADH
DEHYDROGENASE
SUBUNIT


(Pyrococcus
furiosus)
no annotation 5 LEU M 227
ILE M 230
PHE M  68
VAL M 118
GLY M 117
None
0.89A 1e7aB-6cfwM:
undetectable
1e7aB-6cfwM:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fik POLYKETIDE SYNTHASE

(Cercospora
nicotianae)
no annotation 5 LEU A 992
LEU A1233
VAL A1001
GLY A1000
LEU A1193
None
1.21A 1e7aB-6fikA:
undetectable
1e7aB-6fikA:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gpc -

(-)
no annotation 5 LEU A  46
ILE A  42
ARG A   8
VAL A 108
LEU A 115
None
1.19A 1e7aB-6gpcA:
undetectable
1e7aB-6gpcA:
undetectable