SIMILAR PATTERNS OF AMINO ACIDS FOR 1E7A_A_PFLA4002

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f0i PHOSPHOLIPASE D

(Streptomyces
sp. PMF) 		PF13091
(PLDc_2) 		3 PHE A 286
LEU A  18
SER A 324
 None
 0.87A 1e7aA-1f0iA:
undetectable		 1e7aA-1f0iA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1huq RAB5C

(Mus musculus) 		PF00071
(Ras) 		3 PHE A  46
LEU A  37
SER A 164
 GNP  A 200 (-4.1A)
None
GNP  A 200 (-3.5A)
 0.78A 1e7aA-1huqA:
undetectable		 1e7aA-1huqA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR

(Homo sapiens) 		PF01094
(ANF_receptor) 		3 PHE A  22
LEU A  24
SER A  61
 None
None
CL  A 503 (-2.9A)
 0.87A 1e7aA-1jdpA:
0.0		 1e7aA-1jdpA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jj7 PEPTIDE TRANSPORTER
TAP1

(Homo sapiens) 		PF00005
(ABC_tran) 		3 PHE A 624
LEU A 673
SER A 619
 None
 0.75A 1e7aA-1jj7A:
undetectable		 1e7aA-1jj7A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lns X-PROLYL DIPEPTIDYL
AMINOPEPTIDASE

(Lactococcus
lactis) 		PF02129
(Peptidase_S15)
PF08530
(PepX_C)
PF09168
(PepX_N) 		3 PHE A  40
LEU A  51
SER A  46
 None
 0.95A 1e7aA-1lnsA:
2.1		 1e7aA-1lnsA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ojg SENSOR PROTEIN DCUS

(Escherichia
coli) 		PF17203
(sCache_3_2) 		3 PHE A 149
LEU A 129
SER A 105
 None
 0.83A 1e7aA-1ojgA:
undetectable		 1e7aA-1ojgA:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q80 SARCOPLASMIC
CALCIUM-BINDING
PROTEIN

(Hediste
diversicolor) 		PF13202
(EF-hand_5)
PF13499
(EF-hand_7) 		3 PHE A 119
LEU A 145
SER A 133
 None
 0.72A 1e7aA-1q80A:
0.8		 1e7aA-1q80A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tff UBIQUITIN
THIOLESTERASE
PROTEIN OTUB2

(Homo sapiens) 		PF10275
(Peptidase_C65) 		3 PHE A 208
LEU A  56
SER A 184
 None
 0.91A 1e7aA-1tffA:
0.1		 1e7aA-1tffA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w99 PESTICIDIAL CRYSTAL
PROTEIN CRY4BA

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		3 PHE A 264
LEU A 258
SER A 224
 None
 0.85A 1e7aA-1w99A:
3.3		 1e7aA-1w99A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wms RAS-RELATED PROTEIN
RAB-9A

(Homo sapiens) 		PF00071
(Ras) 		3 PHE A  32
LEU A  23
SER A 154
 GDP  A1001 (-4.3A)
None
GDP  A1001 (-3.3A)
 0.73A 1e7aA-1wmsA:
1.4		 1e7aA-1wmsA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x1s RAS-RELATED PROTEIN
M-RAS

(Mus musculus) 		PF00071
(Ras) 		3 PHE A  38
LEU A  29
SER A 156
 GNP  A 179 (-4.2A)
None
GNP  A 179 (-3.6A)
 0.72A 1e7aA-1x1sA:
1.0		 1e7aA-1x1sA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x3s RAS-RELATED PROTEIN
RAB-18

(Homo sapiens) 		PF00071
(Ras) 		3 PHE A  33
LEU A  24
SER A 151
 GNP  A 300 (-4.1A)
None
GNP  A 300 (-3.4A)
 0.70A 1e7aA-1x3sA:
undetectable		 1e7aA-1x3sA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yud HYPOTHETICAL PROTEIN
SO0799

(Shewanella
oneidensis) 		PF06172
(Cupin_5) 		3 PHE A 107
LEU A 134
SER A  52
 None
 0.69A 1e7aA-1yudA:
undetectable		 1e7aA-1yudA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yzp PEROXIDASE
MANGANESE-DEPENDENT
I

(Phanerochaete
chrysosporium) 		PF00141
(peroxidase)
PF11895
(Peroxidase_ext) 		3 PHE A 190
LEU A 170
SER A 241
 HEM  A 396 (-4.9A)
HEM  A 396 (-4.8A)
HEM  A 396 ( 3.7A)
 0.79A 1e7aA-1yzpA:
undetectable		 1e7aA-1yzpA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z06 RAS-RELATED PROTEIN
RAB-33B

(Mus musculus) 		PF00071
(Ras) 		3 PHE A  58
LEU A  49
SER A 178
 GNP  A 204 (-4.6A)
None
GNP  A 204 (-3.2A)
 0.73A 1e7aA-1z06A:
undetectable		 1e7aA-1z06A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z0k GTP-BINDING PROTEIN

(Homo sapiens) 		PF00071
(Ras) 		3 PHE A  33
LEU A  24
SER A 151
 GTP  A1200 (-4.4A)
None
GTP  A1200 (-3.5A)
 0.74A 1e7aA-1z0kA:
undetectable		 1e7aA-1z0kA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT

(Gallus gallus) 		PF00079
(Serpin) 		3 PHE A 149
LEU A 340
SER A 343
 None
 0.86A 1e7aA-2dutA:
undetectable		 1e7aA-2dutA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ek6 RNA-BINDING PROTEIN
12

(Homo sapiens) 		PF00076
(RRM_1) 		3 PHE A  62
LEU A  31
SER A  43
 None
 0.78A 1e7aA-2ek6A:
undetectable		 1e7aA-2ek6A:
9.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eq9 PYRUVATE
DEHYDROGENASE
COMPLEX,
DIHYDROLIPOAMIDE
DEHYDROGENASE E3
COMPONENT

(Thermus
thermophilus) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		3 PHE A 413
LEU A 212
SER A 350
 None
 0.95A 1e7aA-2eq9A:
2.9		 1e7aA-2eq9A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2erx GTP-BINDING PROTEIN
DI-RAS2

(Homo sapiens) 		PF00071
(Ras) 		3 PHE A  32
LEU A  23
SER A 151
 GDP  A 401 (-4.3A)
None
GDP  A 401 (-3.2A)
 0.71A 1e7aA-2erxA:
undetectable		 1e7aA-2erxA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ery RAS-RELATED PROTEIN
R-RAS2

(Homo sapiens) 		PF00071
(Ras) 		3 PHE A  39
LEU A  30
SER A 157
 GDP  A   1 (-4.1A)
None
GDP  A   1 (-3.3A)
 0.71A 1e7aA-2eryA:
undetectable		 1e7aA-2eryA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2faq PROBABLE
ATP-DEPENDENT DNA
LIGASE

(Pseudomonas
aeruginosa) 		no annotation 3 PHE A 757
LEU A 668
SER A 732
 None
 0.72A 1e7aA-2faqA:
undetectable		 1e7aA-2faqA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fn4 RAS-RELATED PROTEIN
R-RAS

(Homo sapiens) 		PF00071
(Ras) 		3 PHE A  54
LEU A  45
SER A 172
 GDP  A   1 ( 4.9A)
None
GDP  A   1 (-3.5A)
 0.75A 1e7aA-2fn4A:
1.3		 1e7aA-2fn4A:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iwg 52 KDA RO PROTEIN

(Homo sapiens) 		PF00622
(SPRY)
PF13765
(PRY) 		3 PHE B 167
LEU B  17
SER B 164
 None
 0.65A 1e7aA-2iwgB:
undetectable		 1e7aA-2iwgB:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ixn SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
ACTIVATOR 2

(Saccharomyces
cerevisiae) 		PF03095
(PTPA) 		3 PHE A 203
LEU A 163
SER A  35
 None
 0.94A 1e7aA-2ixnA:
undetectable		 1e7aA-2ixnA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nvv ACETYL-COA
HYDROLASE/TRANSFERAS
E FAMILY PROTEIN

(Porphyromonas
gingivalis) 		PF02550
(AcetylCoA_hydro)
PF13336
(AcetylCoA_hyd_C) 		3 PHE A  26
LEU A 330
SER A 308
 PHE  A  26 ( 1.3A)
LEU  A 330 ( 0.6A)
SER  A 308 ( 0.0A)
 0.92A 1e7aA-2nvvA:
undetectable		 1e7aA-2nvvA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ocb RAS-RELATED PROTEIN
RAB-9B

(Homo sapiens) 		PF00071
(Ras) 		3 PHE A  32
LEU A  23
SER A 154
 GNP  A 201 (-4.2A)
None
GNP  A 201 (-3.5A)
 0.81A 1e7aA-2ocbA:
undetectable		 1e7aA-2ocbA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2po4 VIRION RNA
POLYMERASE

(Escherichia
virus N4) 		no annotation 3 PHE A 529
LEU A 664
SER A 390
 None
 0.79A 1e7aA-2po4A:
2.1		 1e7aA-2po4A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v73 PUTATIVE
EXO-ALPHA-SIALIDASE

(Clostridium
perfringens) 		PF02973
(Sialidase) 		3 PHE A 145
LEU A  29
SER A  58
 None
 0.66A 1e7aA-2v73A:
undetectable		 1e7aA-2v73A:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vrk ALPHA-L-ARABINOFURAN
OSIDASE

(Thermobacillus
xylanilyticus) 		PF06964
(Alpha-L-AF_C) 		3 PHE A 113
LEU A  38
SER A  27
 None
 0.95A 1e7aA-2vrkA:
undetectable		 1e7aA-2vrkA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ayx MEMBRANE-BOUND
HYDROGENASE LARGE
SUBUNIT

(Hydrogenovibrio
marinus) 		PF00374
(NiFeSe_Hases) 		3 PHE A 458
LEU A 413
SER A 461
 None
 0.82A 1e7aA-3ayxA:
1.9		 1e7aA-3ayxA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3by9 SENSOR PROTEIN

(Vibrio cholerae) 		PF02743
(dCache_1) 		3 PHE A 122
LEU A 118
SER A 114
 SIN  A 287 (-3.7A)
None
None
 0.85A 1e7aA-3by9A:
undetectable		 1e7aA-3by9A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cph RAS-RELATED PROTEIN
SEC4

(Saccharomyces
cerevisiae) 		PF00071
(Ras) 		3 PHE A  45
LEU A  36
SER A 162
 GDP  A 302 (-4.4A)
None
GDP  A 302 (-3.2A)
 0.70A 1e7aA-3cphA:
undetectable		 1e7aA-3cphA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cpj GTP-BINDING PROTEIN
YPT31/YPT8

(Saccharomyces
cerevisiae) 		PF00071
(Ras) 		3 PHE B  38
LEU B  29
SER B 156
 GDP  B1207 (-4.5A)
None
GDP  B1207 (-3.6A)
 0.83A 1e7aA-3cpjB:
undetectable		 1e7aA-3cpjB:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cue TRANSPORT PROTEIN
PARTICLE 22 KDA
SUBUNIT

(Saccharomyces
cerevisiae) 		PF04051
(TRAPP) 		3 PHE D  98
LEU D  90
SER D 151
 None
 0.80A 1e7aA-3cueD:
undetectable		 1e7aA-3cueD:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3doh ESTERASE

(Thermotoga
maritima) 		PF02230
(Abhydrolase_2) 		3 PHE A 116
LEU A 245
SER A 286
 SO4  A 400 (-4.6A)
None
SO4  A 400 (-2.5A)
 0.59A 1e7aA-3dohA:
undetectable		 1e7aA-3dohA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e7w D-ALANINE--POLY(PHOS
PHORIBITOL) LIGASE
SUBUNIT 1

(Bacillus
subtilis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		3 PHE A  69
LEU A 212
SER A 198
 None
 0.84A 1e7aA-3e7wA:
undetectable		 1e7aA-3e7wA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eg5 PROTEIN DIAPHANOUS
HOMOLOG 1

(Mus musculus) 		PF06367
(Drf_FH3)
PF06371
(Drf_GBD) 		3 PHE B 364
LEU B 371
SER B 430
 None
 0.94A 1e7aA-3eg5B:
2.2		 1e7aA-3eg5B:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gf9 INTERSECTIN 2

(Homo sapiens) 		PF00621
(RhoGEF) 		3 PHE A1297
LEU A1304
SER A1214
 None
 0.58A 1e7aA-3gf9A:
2.6		 1e7aA-3gf9A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hum PENICILLIN-BINDING
PROTEIN 4

(Staphylococcus
aureus) 		PF00768
(Peptidase_S11)
PF09211
(DUF1958) 		3 PHE A 369
LEU A 213
SER A  56
 None
 0.88A 1e7aA-3humA:
undetectable		 1e7aA-3humA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ifq E-CADHERIN
PLAKOGLOBIN

(Homo sapiens;
Mus musculus) 		PF00514
(Arm)
PF01049
(Cadherin_C) 		3 PHE C 679
LEU C 676
SER A 380
 None
 0.75A 1e7aA-3ifqC:
undetectable		 1e7aA-3ifqC:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jv3 INTERSECTIN-1

(Mus musculus) 		PF00621
(RhoGEF)
PF14604
(SH3_9) 		3 PHE A1346
LEU A1353
SER A1263
 None
 0.92A 1e7aA-3jv3A:
undetectable		 1e7aA-3jv3A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ka7 OXIDOREDUCTASE

(Methanosarcina
mazei) 		PF01593
(Amino_oxidase) 		3 PHE A  54
LEU A 327
SER A  50
 FAD  A 500 (-4.5A)
None
None
 0.81A 1e7aA-3ka7A:
undetectable		 1e7aA-3ka7A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kq5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Coxiella
burnetii) 		PF07515
(TraI_2_C) 		3 PHE A 218
LEU A 207
SER A 115
 None
 0.85A 1e7aA-3kq5A:
undetectable		 1e7aA-3kq5A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nnr TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY

(Marinobacter
hydrocarbonoclasticus) 		PF00440
(TetR_N)
PF13972
(TetR) 		3 PHE A  45
LEU A  34
SER A  13
 None
 0.94A 1e7aA-3nnrA:
4.0		 1e7aA-3nnrA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oes GTPASE RHEBL1

(Homo sapiens) 		PF00071
(Ras) 		3 PHE A  31
LEU A  22
SER A 149
 GNP  A 201 (-4.3A)
None
GNP  A 201 (-3.6A)
 0.70A 1e7aA-3oesA:
undetectable		 1e7aA-3oesA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q3u LIGNIN PEROXIDASE

(Trametopsis
cervina) 		PF00141
(peroxidase)
PF11895
(Peroxidase_ext) 		3 PHE A 192
LEU A 172
SER A 235
 HEM  A 338 (-4.8A)
HEM  A 338 (-4.9A)
HEM  A 338 (-3.2A)
 0.78A 1e7aA-3q3uA:
undetectable		 1e7aA-3q3uA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE

(Mycobacteroides
abscessus) 		PF01259
(SAICAR_synt) 		3 PHE A  29
LEU A  70
SER A  57
 PHE  A  29 ( 1.3A)
LEU  A  70 ( 0.6A)
SER  A  57 ( 0.0A)
 0.81A 1e7aA-3r9rA:
undetectable		 1e7aA-3r9rA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rap PROTEIN (G PROTEIN
RAP2A)

(Homo sapiens) 		PF00071
(Ras) 		3 PHE R  28
LEU R  19
SER R 146
 GTP  R 180 (-4.3A)
None
GTP  R 180 (-3.4A)
 0.75A 1e7aA-3rapR:
undetectable		 1e7aA-3rapR:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rh2 HYPOTHETICAL
TETR-LIKE
TRANSCRIPTIONAL
REGULATOR

(Shewanella
amazonensis) 		PF00440
(TetR_N)
PF13972
(TetR) 		3 PHE A  43
LEU A  32
SER A  11
 None
 0.90A 1e7aA-3rh2A:
2.8		 1e7aA-3rh2A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rim TRANSKETOLASE

(Mycobacterium
tuberculosis) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		3 PHE A 262
LEU A 200
SER A 189
 None
 0.91A 1e7aA-3rimA:
undetectable		 1e7aA-3rimA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3see HYPOTHETICAL SUGAR
BINDING PROTEIN

(Bacteroides
thetaiotaomicron) 		PF15425
(DUF4627) 		3 PHE A 141
LEU A 195
SER A 156
 None
 0.51A 1e7aA-3seeA:
undetectable		 1e7aA-3seeA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3umm PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE

(Salmonella
enterica) 		PF02769
(AIRS_C)
PF13507
(GATase_5) 		3 PHE A1120
LEU A1076
SER A1109
 None
 0.94A 1e7aA-3ummA:
undetectable		 1e7aA-3ummA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vxc PUTATIVE
SUGAR-BINDING
LIPOPROTEIN

(Streptomyces
thermoviolaceus) 		PF01547
(SBP_bac_1) 		3 PHE A 381
LEU A 292
SER A 376
 None
 0.87A 1e7aA-3vxcA:
undetectable		 1e7aA-3vxcA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wry TM-1 PROTEIN

(Solanum
lycopersicum) 		PF06792
(UPF0261) 		3 PHE A 417
LEU A 266
SER A 424
 None
 0.86A 1e7aA-3wryA:
undetectable		 1e7aA-3wryA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wvs PUTATIVE
MONOOXYGENASE

(Streptomyces
sp. SN-593) 		PF00067
(p450) 		3 PHE A  17
LEU A  43
SER A 291
 None
 0.63A 1e7aA-3wvsA:
1.1		 1e7aA-3wvsA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zx2 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 1

(Rattus
norvegicus) 		PF01150
(GDA1_CD39) 		3 PHE A 364
LEU A 213
SER A 416
 None
 0.85A 1e7aA-3zx2A:
undetectable		 1e7aA-3zx2A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ad8 DNA REPAIR PROTEIN
RECN

(Deinococcus
radiodurans) 		PF02463
(SMC_N) 		3 PHE A 470
LEU A 450
SER A 150
 None
 0.86A 1e7aA-4ad8A:
undetectable		 1e7aA-4ad8A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b2f PUTATIVE ANTIGEN P35

(Borreliella
burgdorferi) 		PF05714
(Borrelia_lipo_1) 		3 PHE A 187
LEU A 181
SER A 273
 None
 0.90A 1e7aA-4b2fA:
undetectable		 1e7aA-4b2fA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bm1 MANGANESE PEROXIDASE
4

(Pleurotus
ostreatus) 		PF00141
(peroxidase)
PF11895
(Peroxidase_ext) 		3 PHE A 193
LEU A 173
SER A 237
 HEM  A 500 (-4.7A)
HEM  A 500 (-4.0A)
HEM  A 500 (-2.7A)
 0.88A 1e7aA-4bm1A:
undetectable		 1e7aA-4bm1A:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4czp EXTRALONG MANGANESE
PEROXIDASE

(Gelatoporia
subvermispora) 		PF00141
(peroxidase)
PF11895
(Peroxidase_ext) 		3 PHE A 190
LEU A 170
SER A 245
 None
HEM  A1374 (-4.6A)
HEM  A1374 (-3.3A)
 0.93A 1e7aA-4czpA:
undetectable		 1e7aA-4czpA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN

(Rhizobium etli) 		PF08240
(ADH_N)
PF13602
(ADH_zinc_N_2) 		3 PHE A 110
LEU A 309
SER A 151
 None
 0.85A 1e7aA-4dvjA:
undetectable		 1e7aA-4dvjA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fcs VERSATILE PEROXIDASE
VPL2

(Pleurotus
eryngii) 		PF00141
(peroxidase)
PF11895
(Peroxidase_ext) 		3 PHE A 186
LEU A 166
SER A 230
 HEM  A 401 (-4.9A)
HEM  A 401 (-4.9A)
HEM  A 401 (-3.5A)
 0.84A 1e7aA-4fcsA:
undetectable		 1e7aA-4fcsA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h0c PHOSPHOLIPASE/CARBOX
YLESTERASE

(Dyadobacter
fermentans) 		PF02230
(Abhydrolase_2) 		3 PHE A  64
LEU A 137
SER A 170
 CIT  A 301 (-4.1A)
None
None
 0.82A 1e7aA-4h0cA:
undetectable		 1e7aA-4h0cA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m8n RAS-RELATED PROTEIN
RAP-1B

(Homo sapiens) 		PF00071
(Ras) 		3 PHE E  28
LEU E  19
SER E 147
 GDP  E 201 (-4.7A)
None
GDP  E 201 (-3.7A)
 0.79A 1e7aA-4m8nE:
undetectable		 1e7aA-4m8nE:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4olp GRPU
MICROCOMPARTMENT
SHELL PROTEIN

(Pectobacterium
parmentieri) 		PF00936
(BMC) 		3 PHE A  66
LEU A  47
SER A  63
 None
 0.84A 1e7aA-4olpA:
undetectable		 1e7aA-4olpA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pmw DIS3-LIKE
EXONUCLEASE 2

(Mus musculus) 		PF00773
(RNB)
PF17216
(Rrp44_CSD1) 		3 PHE A 294
LEU A 317
SER A 320
 None
 0.89A 1e7aA-4pmwA:
undetectable		 1e7aA-4pmwA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pz7 MRNA-CAPPING ENZYME
SUBUNIT ALPHA

(Schizosaccharomyces
pombe) 		PF01331
(mRNA_cap_enzyme)
PF03919
(mRNA_cap_C) 		3 PHE A 144
LEU A 147
SER A  44
 GPL  A  67 ( 3.3A)
None
GPL  A  67 ( 4.9A)
 0.90A 1e7aA-4pz7A:
undetectable		 1e7aA-4pz7A:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6g PYRROLYSINE--TRNA
LIGASE

(Methanosarcina
mazei) 		PF01409
(tRNA-synt_2d) 		3 PHE A 347
LEU A 367
SER A 398
 None
 0.81A 1e7aA-4q6gA:
undetectable		 1e7aA-4q6gA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qed ELXO

(Staphylococcus
epidermidis) 		PF13561
(adh_short_C2) 		3 PHE A 147
LEU A 247
SER A 140
 None
None
NAP  A 300 ( 3.9A)
 0.69A 1e7aA-4qedA:
undetectable		 1e7aA-4qedA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s1i PYRIDOXAL KINASE

(Entamoeba
histolytica) 		PF08543
(Phos_pyr_kin) 		3 PHE B  84
LEU B 114
SER B 129
 None
 0.86A 1e7aA-4s1iB:
2.0		 1e7aA-4s1iB:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uhi STEROL 14-ALPHA
DEMETHYLASE

(Homo sapiens) 		PF00067
(p450) 		3 PHE A 250
LEU A 134
SER A 235
 None
VFV  A 580 (-4.4A)
None
 0.81A 1e7aA-4uhiA:
undetectable		 1e7aA-4uhiA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4um8 INTEGRIN BETA-6

(Homo sapiens) 		PF00362
(Integrin_beta)
PF17205
(PSI_integrin) 		3 PHE B 311
LEU B 320
SER B 257
 None
 0.67A 1e7aA-4um8B:
undetectable		 1e7aA-4um8B:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uoz BETA-GALACTOSIDASE

(Bifidobacterium
animalis) 		PF02449
(Glyco_hydro_42)
PF08532
(Glyco_hydro_42M)
PF08533
(Glyco_hydro_42C) 		3 PHE A  25
LEU A 322
SER A 348
 None
 0.93A 1e7aA-4uozA:
undetectable		 1e7aA-4uozA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4urq DIGUANYLATE CYCLASE

(Thermotoga
maritima) 		PF00990
(GGDEF) 		3 PHE U 121
LEU U 187
SER U 246
 None
 0.70A 1e7aA-4urqU:
undetectable		 1e7aA-4urqU:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z8y RAS-RELATED PROTEIN
SEC4

(Saccharomyces
cerevisiae) 		PF00071
(Ras) 		3 PHE A  45
LEU A  36
SER A 162
 GDP  A 201 (-4.4A)
None
GDP  A 201 (-3.4A)
 0.70A 1e7aA-4z8yA:
undetectable		 1e7aA-4z8yA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus 1) 		PF00078
(RVT_1)
PF06815
(RVT_connect)
PF06817
(RVT_thumb) 		3 PHE B 116
LEU B 120
SER B 156
 None
 0.88A 1e7aA-5c24B:
undetectable		 1e7aA-5c24B:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d1z D4-10 HEAVY CHAIN
IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B

(Homo sapiens;
Staphylococcus
aureus) 		PF05031
(NEAT)
PF07654
(C1-set)
PF07686
(V-set) 		3 PHE I 194
LEU D  73
SER D  31
 None
 0.86A 1e7aA-5d1zI:
undetectable		 1e7aA-5d1zI:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5djq CBB3-TYPE CYTOCHROME
C OXIDASE SUBUNIT
CCON1

(Pseudomonas
stutzeri) 		PF00115
(COX1) 		3 PHE A  17
LEU A  89
SER A  77
 None
 0.74A 1e7aA-5djqA:
1.6		 1e7aA-5djqA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ffo INTEGRIN BETA-6

(Homo sapiens) 		PF00362
(Integrin_beta) 		3 PHE B 311
LEU B 320
SER B 257
 None
 0.69A 1e7aA-5ffoB:
undetectable		 1e7aA-5ffoB:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fre EXO-ALPHA-SIALIDASE

(Clostridium
perfringens) 		PF02973
(Sialidase) 		3 PHE A 147
LEU A  24
SER A  53
 None
 0.45A 1e7aA-5freA:
undetectable		 1e7aA-5freA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h0k UNCHARACTERIZED
PROTEIN

(Pedobacter
heparinus) 		PF16265
(DUF4918) 		3 PHE A 219
LEU A 203
SER A 226
 None
 0.71A 1e7aA-5h0kA:
undetectable		 1e7aA-5h0kA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h64 SERINE/THREONINE-PRO
TEIN KINASE MTOR

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08771
(FRB_dom)
PF11865
(DUF3385) 		3 PHE A2108
LEU A2051
SER A2035
 None
 0.89A 1e7aA-5h64A:
undetectable		 1e7aA-5h64A:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kzl HEME OXYGENASE

(Leptospira
interrogans) 		PF01126
(Heme_oxygenase) 		3 PHE A  69
LEU A  55
SER A 122
 None
 0.93A 1e7aA-5kzlA:
undetectable		 1e7aA-5kzlA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nem INTEGRIN BETA-6

(Homo sapiens) 		PF00362
(Integrin_beta)
PF17205
(PSI_integrin) 		3 PHE B 308
LEU B 317
SER B 254
 None
 0.88A 1e7aA-5nemB:
undetectable		 1e7aA-5nemB:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nfj MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1

(Homo sapiens) 		no annotation 3 PHE A 245
LEU A 254
SER A 311
 None
 0.71A 1e7aA-5nfjA:
undetectable		 1e7aA-5nfjA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opq 3,6-ANHYDRO-D-GALACT
OSIDASE

(Zobellia
galactanivorans) 		no annotation 3 PHE A 588
LEU A 553
SER A 642
 CL  A 704 ( 4.8A)
None
None
 0.83A 1e7aA-5opqA:
undetectable		 1e7aA-5opqA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ty7 PENICILLIN-BINDING
PROTEIN 4

(Staphylococcus
aureus) 		no annotation 3 PHE A 369
LEU A 213
SER A  56
 None
 0.87A 1e7aA-5ty7A:
undetectable		 1e7aA-5ty7A:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uao TRYPTOPHANE-5-HALOGE
NASE

(Microbispora
sp. ATCC
PTA-5024) 		PF04820
(Trp_halogenase) 		3 PHE A 350
LEU A 401
SER A 357
 FAD  A 601 (-4.3A)
None
CL  A 602 (-4.3A)
 0.93A 1e7aA-5uaoA:
undetectable		 1e7aA-5uaoA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ve8 KAP123

(Kluyveromyces
lactis) 		no annotation 3 PHE A1015
LEU A1009
SER A 979
 None
 0.87A 1e7aA-5ve8A:
undetectable		 1e7aA-5ve8A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wdr RAS PROTEIN

(Choanoflagellida) 		PF00071
(Ras) 		3 PHE A  28
LEU A  19
SER A 146
 GNP  A 203 (-4.3A)
None
GNP  A 203 (-3.5A)
 0.74A 1e7aA-5wdrA:
undetectable		 1e7aA-5wdrA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wti CRISPR-ASSOCIATED
PROTEIN

(Bacillus
thermoamylovorans) 		no annotation 3 PHE Z 120
LEU Z 175
SER Z 131
 None
 0.88A 1e7aA-5wtiZ:
undetectable		 1e7aA-5wtiZ:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xr6 RAS-RELATED PROTEIN
RABA1A

(Arabidopsis
thaliana) 		no annotation 3 PHE A  38
LEU A  29
SER A 156
 GNP  A 301 (-4.8A)
None
GNP  A 301 (-3.3A)
 0.68A 1e7aA-5xr6A:
undetectable		 1e7aA-5xr6A:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3r DNA-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08163
(NUC194) 		3 PHE C3942
LEU C3767
SER C3914
 None
 0.93A 1e7aA-5y3rC:
undetectable		 1e7aA-5y3rC:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y50 PROTEIN
DETOXIFICATION 14

(Arabidopsis
thaliana) 		no annotation 3 PHE A 170
LEU A 163
SER A 182
 None
 0.89A 1e7aA-5y50A:
undetectable		 1e7aA-5y50A:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yim SDEA

(Legionella
pneumophila) 		no annotation 3 PHE A 895
LEU A 768
SER A 814
 None
 0.82A 1e7aA-5yimA:
undetectable		 1e7aA-5yimA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ykb TREHALOSE SYNTHASE

(Deinococcus
radiodurans) 		no annotation 3 PHE A 424
LEU A  78
SER A  18
 None
 0.78A 1e7aA-5ykbA:
undetectable		 1e7aA-5ykbA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z2m -

(-) 		no annotation 3 PHE A  33
LEU A  24
SER A 155
 GTP  A 202 (-4.2A)
None
GTP  A 202 (-3.4A)
 0.74A 1e7aA-5z2mA:
undetectable		 1e7aA-5z2mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zkp PLATELET-ACTIVATING
FACTOR
RECEPTOR,FLAVODOXIN,
PLATELET-ACTIVATING
FACTOR RECEPTOR

(Desulfovibrio
vulgaris;
Homo sapiens) 		no annotation 3 PHE A  18
LEU A  70
SER A 283
 9ER  A1201 ( 4.8A)
None
None
 0.90A 1e7aA-5zkpA:
undetectable		 1e7aA-5zkpA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f76 -

(-) 		no annotation 3 PHE B  28
LEU B  19
SER B 145
 GNP  B 202 (-4.3A)
None
GNP  B 202 (-3.6A)
 0.74A 1e7aA-6f76B:
undetectable		 1e7aA-6f76B:
undetectable