SIMILAR PATTERNS OF AMINO ACIDS FOR 1E7A_A_PFLA4001_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dml | DNA POLYMERASEPROCESSIVITY FACTOR (Humanalphaherpesvirus1) |
PF02282(Herpes_UL42) | 5 | LEU A 288LEU A 189VAL A 283GLY A 284ALA A 303 | None | 1.31A | 1e7aA-1dmlA:undetectable | 1e7aA-1dmlA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h71 | SERRALYSIN (Pseudomonas sp.'TAC II 18') |
PF00413(Peptidase_M10)PF08548(Peptidase_M10_C) | 5 | ILE P 236LEU P 247VAL P 323GLY P 322ALA P 320 | None | 1.21A | 1e7aA-1h71P:undetectable | 1e7aA-1h71P:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k3g | CYTOCHROME C-553 (Sporosarcinapasteurii) |
PF13442(Cytochrome_CBB3) | 5 | LEU A 61ILE A 64VAL A 27CYH A 32ALA A 76 | NoneHEC A 93 (-3.6A)NoneHEC A 93 (-1.8A)HEC A 93 ( 3.6A) | 1.00A | 1e7aA-1k3gA:undetectable | 1e7aA-1k3gA:8.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nt2 | FIBRILLARIN-LIKEPRE-RRNA PROCESSINGPROTEIN (Archaeoglobusfulgidus) |
PF01269(Fibrillarin) | 5 | LEU A 143ILE A 142VAL A 87GLY A 65ALA A 114 | NoneNoneNoneSAM A 301 ( 3.8A)SAM A 301 (-3.4A) | 1.21A | 1e7aA-1nt2A:undetectable | 1e7aA-1nt2A:14.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oed | ACETYLCHOLINERECEPTOR PROTEIN,GAMMA CHAIN (Torpedomarmorata) |
PF02932(Neur_chan_memb) | 5 | LEU E 457ILE E 454ASN E 300VAL E 307ALA E 450 | None | 0.93A | 1e7aA-1oedE:3.1 | 1e7aA-1oedE:17.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sq7 | TRIOSEPHOSPHATEISOMERASE (Gallus gallus) |
PF00121(TIM) | 5 | LEU A 24ILE A 25VAL A 61GLY A 60ALA A 51 | None | 1.06A | 1e7aA-1sq7A:undetectable | 1e7aA-1sq7A:18.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 8 | LEU A 387ILE A 388ASN A 391LEU A 407ARG A 410VAL A 433GLY A 434ALA A 449 | None | 0.74A | 1e7aA-1tf0A:47.1 | 1e7aA-1tf0A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tqy | ACTINORHODINPOLYKETIDE PUTATIVEBETA-KETOACYLSYNTHASE 2 (Streptomycescoelicolor) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | LEU B 234ILE B 233VAL B 11GLY B 230ALA B 78 | None | 1.30A | 1e7aA-1tqyB:undetectable | 1e7aA-1tqyB:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v9t | CYCLOPHILIN B (Escherichiacoli) |
PF00160(Pro_isomerase) | 5 | LEU A 160ILE A 159ASN A 43GLY A 39ALA A 162 | None | 1.29A | 1e7aA-1v9tA:undetectable | 1e7aA-1v9tA:14.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vbg | PYRUVATE,ORTHOPHOSPHATE DIKINASE (Zea mays) |
PF00391(PEP-utilizers)PF01326(PPDK_N)PF02896(PEP-utilizers_C) | 5 | LEU A 499ILE A 428VAL A 471GLY A 503CYH A 469 | None | 1.23A | 1e7aA-1vbgA:undetectable | 1e7aA-1vbgA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vcg | ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE (Thermusthermophilus) |
PF01070(FMN_dh) | 5 | LEU A 277ILE A 247VAL A 265GLY A 263ALA A 261 | NoneNoneNoneFMN A 501 (-3.2A)None | 1.28A | 1e7aA-1vcgA:undetectable | 1e7aA-1vcgA:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ve2 | UROPORPHYRIN-IIIC-METHYLTRANSFERASE (Thermusthermophilus) |
PF00590(TP_methylase) | 5 | LEU A 215LEU A 129VAL A 222GLY A 219ALA A 183 | None | 1.30A | 1e7aA-1ve2A:undetectable | 1e7aA-1ve2A:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ybd | URIDYLATE KINASE (Neisseriameningitidis) |
PF00696(AA_kinase) | 5 | LEU A 21ILE A 34LEU A 14GLY A 39ALA A 94 | None | 1.17A | 1e7aA-1ybdA:undetectable | 1e7aA-1ybdA:16.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yob | FLAVODOXIN 2 (Azotobactervinelandii) |
PF00258(Flavodoxin_1) | 5 | LEU A 168ILE A 171LEU A 151GLY A 148ALA A 92 | None | 0.78A | 1e7aA-1yobA:undetectable | 1e7aA-1yobA:15.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c3z | INDOLE-3-GLYCEROLPHOSPHATE SYNTHASE (Sulfolobussolfataricus) |
PF00218(IGPS) | 5 | LEU A 38ILE A 37ASN A 34ARG A 175ALA A 229 | None | 1.21A | 1e7aA-2c3zA:undetectable | 1e7aA-2c3zA:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ffj | CONSERVEDHYPOTHETICAL PROTEIN (Archaeoglobusfulgidus) |
PF01937(DUF89) | 5 | ILE A 29LEU A 37VAL A 15GLY A 13ALA A 19 | None | 1.31A | 1e7aA-2ffjA:2.8 | 1e7aA-2ffjA:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2flq | NITRIC OXIDESYNTHASE (Geobacillusstearothermophilus) |
PF02898(NO_synthase) | 5 | LEU A 213ILE A 202LEU A 263GLY A 250ALA A 292 | None | 1.11A | 1e7aA-2flqA:2.4 | 1e7aA-2flqA:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gzx | PUTATIVE TATDRELATED DNASE (Staphylococcusaureus) |
PF01026(TatD_DNase) | 5 | ILE A 90LEU A 140VAL A 148GLY A 149ALA A 118 | None | 1.23A | 1e7aA-2gzxA:undetectable | 1e7aA-2gzxA:16.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hj9 | AUTOINDUCER2-BINDINGPERIPLASMIC PROTEINLUXP (Vibrio harveyi) |
PF13407(Peripla_BP_4) | 5 | LEU A 304ILE A 286VAL A 268GLY A 244ALA A 263 | None | 1.18A | 1e7aA-2hj9A:undetectable | 1e7aA-2hj9A:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2imh | HYPOTHETICAL PROTEINUNP Q5LQD5_SILPO (Ruegeriapomeroyi) |
PF06267(DUF1028) | 5 | LEU A 6ILE A 114LEU A 59VAL A 69ALA A 95 | None | 1.26A | 1e7aA-2imhA:undetectable | 1e7aA-2imhA:16.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iq7 | ENDOPOLYGALACTURONASE (Colletotrichumlupini) |
PF00295(Glyco_hydro_28) | 5 | LEU A 142ILE A 103ASN A 140VAL A 162GLY A 138 | None | 1.30A | 1e7aA-2iq7A:undetectable | 1e7aA-2iq7A:17.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jfd | FATTY ACID SYNTHASE (Homo sapiens) |
PF00698(Acyl_transf_1)PF16197(KAsynt_C_assoc) | 5 | LEU A 805LEU A 438VAL A 472GLY A 478ALA A 798 | None | 1.25A | 1e7aA-2jfdA:1.7 | 1e7aA-2jfdA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q1y | CELL DIVISIONPROTEIN FTSZ (Mycobacteriumtuberculosis) |
PF00091(Tubulin)PF12327(FtsZ_C) | 5 | LEU A 89ILE A 86LEU A 47VAL A 58ALA A 82 | None | 1.19A | 1e7aA-2q1yA:undetectable | 1e7aA-2q1yA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q1y | CELL DIVISIONPROTEIN FTSZ (Mycobacteriumtuberculosis) |
PF00091(Tubulin)PF12327(FtsZ_C) | 5 | LEU A 258ILE A 308LEU A 124GLY A 127ALA A 221 | None | 1.15A | 1e7aA-2q1yA:undetectable | 1e7aA-2q1yA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vxg | CG6181-PA, ISOFORM A (Drosophilamelanogaster) |
no annotation | 5 | ILE A1222LEU A1289VAL A1247GLY A1245ALA A1238 | None | 1.13A | 1e7aA-2vxgA:undetectable | 1e7aA-2vxgA:13.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wc1 | FLAVODOXIN (Rhodobactercapsulatus) |
PF00258(Flavodoxin_1) | 5 | LEU A 169ILE A 172LEU A 152GLY A 149ALA A 93 | None | 0.78A | 1e7aA-2wc1A:undetectable | 1e7aA-2wc1A:13.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2whk | MANNANENDO-1,4-BETA-MANNOSIDASE (Bacillussubtilis) |
PF02156(Glyco_hydro_26) | 5 | ILE A 249LEU A 313VAL A 267GLY A 268ALA A 241 | None | 1.30A | 1e7aA-2whkA:undetectable | 1e7aA-2whkA:19.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zxh | TRNA URIDINE5-CARBOXYMETHYLAMINOMETHYL MODIFICATIONENZYME MNMG (Aquifexaeolicus) |
PF01134(GIDA)PF13932(GIDA_assoc) | 5 | LEU A 400ASN A 397LEU A 410GLY A 391ALA A 25 | None | 1.04A | 1e7aA-2zxhA:undetectable | 1e7aA-2zxhA:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3av6 | DNA(CYTOSINE-5)-METHYLTRANSFERASE 1 (Mus musculus) |
PF00145(DNA_methylase)PF01426(BAH)PF02008(zf-CXXC)PF12047(DNMT1-RFD) | 5 | LEU A 598ASN A 696VAL A 658GLY A 657CYH A 662 | NoneNoneNoneNone ZN A2002 (-2.1A) | 1.27A | 1e7aA-3av6A:undetectable | 1e7aA-3av6A:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aw9 | NAD-DEPENDENTEPIMERASE/DEHYDRATASE (Pyrobaculumcalidifontis) |
PF01370(Epimerase) | 5 | LEU A 16ILE A 12LEU A 156VAL A 228ALA A 205 | NoneNAD A 901 (-4.4A)NoneNoneNone | 1.14A | 1e7aA-3aw9A:undetectable | 1e7aA-3aw9A:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dc7 | PUTATIVEUNCHARACTERIZEDPROTEIN LP_3323 (Lactobacillusplantarum) |
PF13472(Lipase_GDSL_2) | 5 | LEU A 46ILE A 45LEU A 180VAL A 211GLY A 208 | None | 1.18A | 1e7aA-3dc7A:undetectable | 1e7aA-3dc7A:16.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dj4 | BIFUNCTIONAL PROTEINGLMU (Mycobacteriumtuberculosis) |
PF00132(Hexapep)PF12804(NTP_transf_3) | 5 | LEU A 56ILE A 63LEU A 41VAL A 67GLY A 68 | None | 1.10A | 1e7aA-3dj4A:undetectable | 1e7aA-3dj4A:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dy5 | ALLENE OXIDESYNTHASE-LIPOXYGENASE PROTEIN (Plexaurahomomalla) |
PF00305(Lipoxygenase)PF01477(PLAT) | 5 | ILE A 716LEU A 984VAL A 746GLY A 745ALA A 695 | None | 0.99A | 1e7aA-3dy5A:undetectable | 1e7aA-3dy5A:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3enq | RIBOSE-5-PHOSPHATEISOMERASE A (Vibriovulnificus) |
PF06026(Rib_5-P_isom_A) | 5 | LEU A 63ILE A 65LEU A 15VAL A 24ALA A 49 | None | 1.19A | 1e7aA-3enqA:undetectable | 1e7aA-3enqA:17.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ez0 | UNCHARACTERIZEDPROTEIN WITHFERRITIN-LIKE FOLD (Arthrobactersp. FB24) |
PF13794(MiaE_2) | 5 | LEU A 209ILE A 206ARG A 216GLY A 170ALA A 176 | NoneNoneNoneNoneUNL A 500 ( 4.1A) | 1.32A | 1e7aA-3ez0A:undetectable | 1e7aA-3ez0A:17.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fgt | PUTATIVEPHOSPHOLIPASE B-LIKE2 28 KDA FORM (Mus musculus) |
PF04916(Phospholip_B) | 5 | LEU A 118LEU A 205VAL A 126GLY A 124ALA A 90 | NAG A 11 ( 4.3A)NoneNoneNoneNone | 1.25A | 1e7aA-3fgtA:undetectable | 1e7aA-3fgtA:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fgw | PUTATIVEPHOSPHOLIPASE B-LIKE2 (Mus musculus) |
PF04916(Phospholip_B) | 5 | LEU A 118LEU A 205VAL A 126GLY A 124ALA A 90 | NAG A 11 ( 4.6A)NoneNoneNoneNone | 1.20A | 1e7aA-3fgwA:undetectable | 1e7aA-3fgwA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fi9 | MALATE DEHYDROGENASE (Porphyromonasgingivalis) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | LEU A 207ILE A 202ARG A 218VAL A 186ALA A 188 | None | 1.28A | 1e7aA-3fi9A:undetectable | 1e7aA-3fi9A:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gaz | ALCOHOLDEHYDROGENASESUPERFAMILY PROTEIN (Novosphingobiumaromaticivorans) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ILE A 156LEU A 246VAL A 163GLY A 162ALA A 167 | NoneNoneNone CA A 401 ( 3.7A)None | 1.21A | 1e7aA-3gazA:undetectable | 1e7aA-3gazA:18.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gg2 | SUGAR DEHYDROGENASE,UDP-GLUCOSE/GDP-MANNOSE DEHYDROGENASEFAMILY (Porphyromonasgingivalis) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 5 | LEU A 423ILE A 420LEU A 465VAL A 468GLY A 401 | None | 1.26A | 1e7aA-3gg2A:undetectable | 1e7aA-3gg2A:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iha | SALT-TOLERANTGLUTAMINASE (Micrococcusluteus) |
PF04960(Glutaminase) | 5 | LEU A 304ILE A 255LEU A 9VAL A 277GLY A 276 | None | 1.28A | 1e7aA-3ihaA:undetectable | 1e7aA-3ihaA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k8k | ALPHA-AMYLASE, SUSG (Bacteroidesthetaiotaomicron) |
PF00128(Alpha-amylase) | 5 | LEU A 680ASN A 643LEU A 515GLY A 467ALA A 628 | None | 1.29A | 1e7aA-3k8kA:undetectable | 1e7aA-3k8kA:23.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kao | TAGATOSE1,6-DIPHOSPHATEALDOLASE (Staphylococcusaureus) |
PF01791(DeoC) | 5 | LEU A 24ILE A 67LEU A 32GLY A 74ALA A 57 | None | 1.30A | 1e7aA-3kaoA:undetectable | 1e7aA-3kaoA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3led | 3-OXOACYL-ACYLCARRIER PROTEINSYNTHASE III (Rhodopseudomonaspalustris) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | LEU A 163ILE A 222VAL A 170GLY A 171ALA A 4 | None | 1.28A | 1e7aA-3ledA:undetectable | 1e7aA-3ledA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m7a | UNCHARACTERIZEDPROTEIN (Novosphingobiumaromaticivorans) |
PF02643(DUF192) | 5 | LEU A 145ILE A 112LEU A 82GLY A 149ALA A 152 | None | 1.13A | 1e7aA-3m7aA:undetectable | 1e7aA-3m7aA:12.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ngo | CCR4-NOTTRANSCRIPTIONCOMPLEX SUBUNIT6-LIKE (Homo sapiens) |
PF03372(Exo_endo_phos) | 5 | LEU A 532ILE A 491ARG A 172GLY A 502ALA A 469 | None | 1.29A | 1e7aA-3ngoA:undetectable | 1e7aA-3ngoA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3poy | NEUREXIN-1-ALPHA (Bos taurus) |
PF00008(EGF)PF02210(Laminin_G_2) | 5 | LEU A 638ILE A 514VAL A 691GLY A 690ALA A 683 | None | 1.27A | 1e7aA-3poyA:undetectable | 1e7aA-3poyA:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qqz | PUTATIVEUNCHARACTERIZEDPROTEIN YJIK (Escherichiacoli) |
PF06977(SdiA-regulated) | 5 | LEU A 240LEU A 280VAL A 297GLY A 296ALA A 246 | None | 1.01A | 1e7aA-3qqzA:undetectable | 1e7aA-3qqzA:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qvm | OLEI00960 (Oleispiraantarctica) |
PF00561(Abhydrolase_1) | 5 | LEU A 181ILE A 182ARG A 44GLY A 187ALA A 169 | SO4 A 283 (-4.4A)NoneSO4 A 284 (-3.6A)NoneNone | 1.07A | 1e7aA-3qvmA:undetectable | 1e7aA-3qvmA:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r4t | 4-AMINOBUTYRATEAMINOTRANSFERASEGABT (Mycobacteriummarinum) |
PF00202(Aminotran_3) | 5 | LEU A 443ILE A 442LEU A 358GLY A 435ALA A 402 | None | 1.26A | 1e7aA-3r4tA:undetectable | 1e7aA-3r4tA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqh | QUINONEOXIDOREDUCTASE (Coxiellaburnetii) |
PF08240(ADH_N)PF13602(ADH_zinc_N_2) | 5 | LEU A 275LEU A 142VAL A 162GLY A 163ALA A 134 | NoneNoneNDP A 500 (-3.7A)NoneNone | 1.10A | 1e7aA-3tqhA:undetectable | 1e7aA-3tqhA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vi1 | ALKALINEMETALLOPROTEINASE (Pseudomonasaeruginosa) |
PF08548(Peptidase_M10_C)PF13583(Reprolysin_4) | 5 | ILE A 239LEU A 250VAL A 326GLY A 325ALA A 323 | None | 1.22A | 1e7aA-3vi1A:undetectable | 1e7aA-3vi1A:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vpr | TRANSCRIPTIONALREGULATOR, TETRFAMILY (Thermusthermophilus) |
PF00440(TetR_N) | 5 | LEU A 130ILE A 129LEU A 155GLY A 66ALA A 78 | None | 1.22A | 1e7aA-3vprA:3.4 | 1e7aA-3vprA:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4atg | TAF6 (Antonosporalocustae) |
PF07571(TAF6_C) | 5 | LEU A 319ILE A 318VAL A 255GLY A 311ALA A 270 | None | 1.07A | 1e7aA-4atgA:2.1 | 1e7aA-4atgA:16.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cyl | EFF-1A (Caenorhabditiselegans) |
PF14884(EFF-AFF) | 5 | LEU A 465ILE A 388VAL A 438GLY A 414ALA A 412 | None | 1.00A | 1e7aA-4cylA:undetectable | 1e7aA-4cylA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e6e | CELL DIVISIONPROTEIN FTSZ (Thermobifidafusca) |
PF00091(Tubulin)PF12327(FtsZ_C) | 5 | LEU A 258ILE A 308LEU A 124GLY A 127ALA A 221 | None | 1.25A | 1e7aA-4e6eA:undetectable | 1e7aA-4e6eA:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ej6 | PUTATIVEZINC-BINDINGDEHYDROGENASE (Sinorhizobiummeliloti) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ILE A 220LEU A 281ARG A 279VAL A 234ALA A 164 | NoneNoneEDO A 409 ( 3.7A)NoneNone | 1.21A | 1e7aA-4ej6A:undetectable | 1e7aA-4ej6A:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fs3 | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADPH] FABI (Staphylococcusaureus) |
PF13561(adh_short_C2) | 5 | LEU A 208ILE A 207ASN A 205VAL A 201GLY A 202 | None0WE A 302 ( 4.8A)None0WE A 302 ( 4.4A)None | 1.04A | 1e7aA-4fs3A:undetectable | 1e7aA-4fs3A:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i7a | ETHANOLAMINEUTILIZATION PROTEINEUTN/CARBOXYSOMESTRUCTURAL PROTEINCCML (Rhodospirillumrubrum) |
PF03319(EutN_CcmL) | 5 | ILE A 81LEU A 30VAL A 6GLY A 52ALA A 49 | None | 1.14A | 1e7aA-4i7aA:undetectable | 1e7aA-4i7aA:8.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4il1 | CALMODULIN,CALCINEURIN SUBUNITB TYPE 1,SERINE/THREONINE-PROTEIN PHOSPHATASE 2BCATALYTIC SUBUNITALPHA ISOFORM (Rattusnorvegicus) |
PF00149(Metallophos)PF13499(EF-hand_7) | 5 | LEU A 542ILE A 545VAL A 531GLY A 534ALA A 521 | None | 1.19A | 1e7aA-4il1A:2.4 | 1e7aA-4il1A:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jej | GERANYLGERANYLGLYCERYL PHOSPHATESYNTHASE (Flavobacteriumjohnsoniae) |
PF01884(PcrB) | 5 | LEU A 191ILE A 194VAL A 228GLY A 208ALA A 225 | NoneNoneNone1GP A 301 (-3.4A)None | 1.03A | 1e7aA-4jejA:undetectable | 1e7aA-4jejA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lgl | GLYCINEDEHYDROGENASE[DECARBOXYLATING] (Synechocystissp. PCC 6803) |
PF02347(GDC-P) | 5 | LEU A 432LEU A 393VAL A 413GLY A 412ALA A 418 | None | 1.10A | 1e7aA-4lglA:undetectable | 1e7aA-4lglA:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o6i | NUCLEOPROTEIN (Lymphocyticchoriomeningitismammarenavirus) |
PF17290(Arena_ncap_C) | 5 | LEU A 544ILE A 543ASN A 542LEU A 520GLY A 401 | None | 1.04A | 1e7aA-4o6iA:undetectable | 1e7aA-4o6iA:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4obu | PYRIDOXAL-DEPENDENTDECARBOXYLASE DOMAINPROTEIN ([Ruminococcus]gnavus) |
no annotation | 5 | LEU E 167ILE E 164ASN E 163VAL E 156GLY E 158 | NoneNonePLP E 501 ( 4.4A)NonePLP E 501 ( 4.3A) | 1.27A | 1e7aA-4obuE:undetectable | 1e7aA-4obuE:20.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 6 | LEU A 387ASN A 391LEU A 407ARG A 410VAL A 433GLY A 434 | NPS A 601 ( 4.7A)NPS A 601 (-4.3A)NPS A 601 ( 4.9A)NPS A 601 (-4.5A)NoneNone | 0.53A | 1e7aA-4po0A:47.8 | 1e7aA-4po0A:74.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rnh | MOTILITY REGULATOR (Pseudomonasaeruginosa) |
PF00563(EAL)PF00990(GGDEF) | 5 | LEU A1267ILE A1266LEU A1279GLY A1221ALA A1226 | None | 1.20A | 1e7aA-4rnhA:undetectable | 1e7aA-4rnhA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u39 | CELL DIVISIONPROTEIN FTSZ (Bacillussubtilis) |
PF00091(Tubulin)PF12327(FtsZ_C) | 5 | LEU A 261ILE A 311LEU A 127GLY A 130ALA A 224 | None | 1.28A | 1e7aA-4u39A:undetectable | 1e7aA-4u39A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u9i | PERIPLASMIC [NIFE]HYDROGENASE LARGESUBUNITPERIPLASMIC [NIFE]HYDROGENASE SMALLSUBUNIT (Desulfovibriovulgaris) |
PF00374(NiFeSe_Hases)PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C) | 5 | LEU L 57LEU L 61GLY S 119CYH S 114ALA S 130 | NoneNoneNoneSF4 S2001 (-2.2A)None | 1.30A | 1e7aA-4u9iL:undetectable | 1e7aA-4u9iL:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4umv | ZINC-TRANSPORTINGATPASE (Shigella sonnei) |
PF00122(E1-E2_ATPase)PF00702(Hydrolase) | 5 | LEU A 531ILE A 532LEU A 462VAL A 551ALA A 525 | None | 1.21A | 1e7aA-4umvA:undetectable | 1e7aA-4umvA:24.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4upl | SULFATASE FAMILYPROTEIN (Ruegeriapomeroyi) |
PF00884(Sulfatase)PF16347(DUF4976) | 5 | LEU A 403ILE A 400ARG A 364VAL A 0ALA A 384 | None | 1.01A | 1e7aA-4uplA:undetectable | 1e7aA-4uplA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w5k | ASPARTATEAMINOTRANSFERASE,MITOCHONDRIAL (Trypanosomabrucei) |
PF00155(Aminotran_1_2) | 5 | LEU A 316ILE A 332LEU A 352GLY A 343ALA A 340 | NoneNoneNoneEDO A 502 (-3.5A)None | 1.00A | 1e7aA-4w5kA:undetectable | 1e7aA-4w5kA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wxp | NS3-4 PROTEASE (Hepacivirus C) |
PF07652(Flavi_DEAD) | 5 | LEU A 226ILE A 287LEU A 274GLY A 304ALA A 310 | None | 1.13A | 1e7aA-4wxpA:undetectable | 1e7aA-4wxpA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x0o | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 3 PROTEIN 2 (Vibrio cholerae) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | LEU A 261ILE A 257LEU A 117GLY A 312ALA A 223 | NoneNoneNoneSCY A 113 ( 3.1A)None | 1.26A | 1e7aA-4x0oA:undetectable | 1e7aA-4x0oA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y0w | YEAZ (Pseudomonasaeruginosa) |
PF00814(Peptidase_M22) | 5 | LEU A 5ILE A 60LEU A 40GLY A 77ALA A 83 | None | 1.21A | 1e7aA-4y0wA:undetectable | 1e7aA-4y0wA:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z6g | MICROTUBULE-ACTINCROSS-LINKING FACTOR1, ISOFORMS 1/2/3/5 (Homo sapiens) |
PF00307(CH) | 5 | LEU A 199ILE A 200VAL A 234GLY A 233ALA A 229 | None | 1.29A | 1e7aA-4z6gA:undetectable | 1e7aA-4z6gA:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a31 | ANAPHASE-PROMOTINGCOMPLEX SUBUNIT 1 (Homo sapiens) |
PF12859(ANAPC1) | 5 | LEU A1307LEU A1612VAL A1255GLY A1256ALA A1301 | None | 1.19A | 1e7aA-5a31A:2.6 | 1e7aA-5a31A:17.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a6s | ENDOLYSIN (Clostridiumphage phiCTP1) |
PF01183(Glyco_hydro_25) | 5 | ASN A 224LEU A 250VAL A 239GLY A 240ALA A 210 | None | 1.29A | 1e7aA-5a6sA:undetectable | 1e7aA-5a6sA:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bp1 | MYCOCEROSIC ACIDSYNTHASE (Mycolicibacteriumsmegmatis) |
PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | ILE A 161LEU A 250VAL A 247GLY A 203ALA A 103 | None | 1.10A | 1e7aA-5bp1A:undetectable | 1e7aA-5bp1A:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bz4 | BETA-KETOTHIOLASE (Mycolicibacteriumsmegmatis) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | LEU A 55ILE A 54LEU A 39VAL A 267ALA A 100 | None | 1.21A | 1e7aA-5bz4A:undetectable | 1e7aA-5bz4A:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cx8 | LIPOPROTEIN RAGB (Porphyromonasgingivalis) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 5 | LEU A 386ILE A 387LEU A 265VAL A 260ALA A 256 | None | 1.31A | 1e7aA-5cx8A:undetectable | 1e7aA-5cx8A:22.98 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 6 | LEU A 386ASN A 390LEU A 406ARG A 409VAL A 432GLY A 433 | None | 0.76A | 1e7aA-5dqfA:48.6 | 1e7aA-5dqfA:76.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 5 | LEU A 547ASN A 404VAL A 423GLY A 426ALA A 529 | NoneNonePG4 A 604 ( 4.9A)NoneNone | 1.16A | 1e7aA-5dqfA:48.6 | 1e7aA-5dqfA:76.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f9s | SERINE--PYRUVATEAMINOTRANSFERASE (Homo sapiens) |
PF00266(Aminotran_5) | 5 | LEU A 76ILE A 220LEU A 272GLY A 206ALA A 85 | None | 1.31A | 1e7aA-5f9sA:undetectable | 1e7aA-5f9sA:20.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 6 | LEU A 387ASN A 391LEU A 407ARG A 410VAL A 433GLY A 434 | None | 0.61A | 1e7aA-5ghkA:45.6 | 1e7aA-5ghkA:79.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 6 | LEU A 387ASN A 391LEU A 407VAL A 433GLY A 434ALA A 449 | None | 0.48A | 1e7aA-5ghkA:45.6 | 1e7aA-5ghkA:79.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i4c | TRANSCRIPTIONALREGULATORY PROTEINRCSB (Escherichiacoli) |
PF00072(Response_reg) | 5 | LEU A 23ILE A 19LEU A 123VAL A 107ALA A 112 | None | 0.99A | 1e7aA-5i4cA:undetectable | 1e7aA-5i4cA:12.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i4q | CONTACT-DEPENDENTINHIBITOR A (Escherichiacoli) |
no annotation | 5 | LEU A 235LEU A 195ARG A 200VAL A 246GLY A 247 | None | 1.10A | 1e7aA-5i4qA:undetectable | 1e7aA-5i4qA:9.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i7n | MAOC-LIKEDEHYDRATASE (Mycobacteroidesabscessus) |
PF01575(MaoC_dehydratas)PF13452(MaoC_dehydrat_N) | 5 | LEU A 266ILE A 302VAL A 294GLY A 299ALA A 292 | None | 0.97A | 1e7aA-5i7nA:undetectable | 1e7aA-5i7nA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lcw | ANAPHASE-PROMOTINGCOMPLEX SUBUNIT 1 (Homo sapiens) |
PF12859(ANAPC1) | 5 | LEU A1307LEU A1612VAL A1255GLY A1256ALA A1301 | None | 1.14A | 1e7aA-5lcwA:2.7 | 1e7aA-5lcwA:14.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mn5 | CELL DIVISIONPROTEIN FTSZ (Staphylococcusaureus) |
PF00091(Tubulin)PF12327(FtsZ_C) | 5 | LEU A 261ILE A 311LEU A 127GLY A 130ALA A 224 | None | 1.25A | 1e7aA-5mn5A:undetectable | 1e7aA-5mn5A:18.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 5 | ASN A 390LEU A 406ARG A 409VAL A 432GLY A 433 | None | 0.79A | 1e7aA-5oriA:48.1 | 1e7aA-5oriA:74.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 6 | LEU A 386ILE A 387ASN A 390LEU A 406VAL A 432GLY A 433 | None | 0.83A | 1e7aA-5oriA:48.1 | 1e7aA-5oriA:74.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5szm | PCDHGA8 ORPROTOCADHERIN GAMMAA8 (Mus musculus) |
PF00028(Cadherin)PF08266(Cadherin_2) | 5 | LEU A 48ILE A 37LEU A 23VAL A 90GLY A 89 | None | 1.29A | 1e7aA-5szmA:undetectable | 1e7aA-5szmA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t6o | POLY-BETA-HYDROXYBUTERATE POLYMERASE (Cupriavidusnecator) |
PF07167(PhaC_N) | 5 | ILE A 293LEU A 345VAL A 243GLY A 321ALA A 297 | None | 1.28A | 1e7aA-5t6oA:undetectable | 1e7aA-5t6oA:19.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xcy | GLUCANASE (Phanerochaetechrysosporium) |
PF01341(Glyco_hydro_6) | 5 | LEU A 130ILE A 163LEU A 143VAL A 253ALA A 211 | None | 1.26A | 1e7aA-5xcyA:undetectable | 1e7aA-5xcyA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 7 | LEU A 387ASN A 391LEU A 407ARG A 410VAL A 433GLY A 434ALA A 449 | None | 0.79A | 1e7aA-5yxeA:47.4 | 1e7aA-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b3y | DENNDOMAIN-CONTAININGPROTEIN 3 (Mus musculus) |
no annotation | 5 | LEU A 827LEU A 807VAL A 811GLY A 818ALA A 877 | None | 1.18A | 1e7aA-6b3yA:undetectable | 1e7aA-6b3yA:9.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bxn | DIPHTHAMIDEBIOSYNTHESIS ENZYMEDPH2 (CandidatusMethanoperedensnitroreducens) |
no annotation | 5 | LEU A 12ILE A 15VAL A 50GLY A 24ALA A 48 | None | 0.97A | 1e7aA-6bxnA:undetectable | 1e7aA-6bxnA:7.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c9d | SERINE/THREONINE-PROTEIN KINASEMARK1,SERINE/THREONINE-PROTEIN KINASEMARK1 (Homo sapiens) |
no annotation | 5 | LEU A 76LEU A 700ARG A 698GLY A 142ALA A 139 | None | 1.24A | 1e7aA-6c9dA:undetectable | 1e7aA-6c9dA:8.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g1k | TRANSIENT RECEPTORPOTENTIAL CATIONCHANNEL SUBFAMILY CMEMBER 4A (Danio rerio) |
no annotation | 5 | LEU A 74ILE A 78VAL A 112GLY A 110ALA A 103 | None | 1.11A | 1e7aA-6g1kA:3.6 | 1e7aA-6g1kA:8.74 |