SIMILAR PATTERNS OF AMINO ACIDS FOR 1E71_M_ASCM995

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1byw PROTEIN (HUMAN ERG
POTASSIUM CHANNEL)


(Homo sapiens)
PF13426
(PAS_9)
4 ILE A  82
PHE A 129
PHE A  48
PHE A  68
None
1.20A 1e71M-1bywA:
undetectable
1e71M-1bywA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1byw PROTEIN (HUMAN ERG
POTASSIUM CHANNEL)


(Homo sapiens)
PF13426
(PAS_9)
4 ILE A  96
PHE A 129
PHE A  48
PHE A  68
None
1.01A 1e71M-1bywA:
undetectable
1e71M-1bywA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cen CELLULASE CELC

(Ruminiclostridium
thermocellum)
PF00150
(Cellulase)
4 GLN A 140
TYR A 200
PHE A 203
PHE A 320
BGC  A 351 (-2.8A)
BGC  A 351 (-4.3A)
None
BGC  A 351 ( 4.2A)
0.95A 1e71M-1cenA:
20.6
1e71M-1cenA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cle CHOLESTEROL ESTERASE

([Candida]
cylindracea)
PF00135
(COesterase)
4 ILE A 453
TYR A 467
PHE A 471
PHE A 434
CLL  A 801 (-3.9A)
None
None
None
1.04A 1e71M-1cleA:
1.4
1e71M-1cleA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1crl LIPASE

(Diutina rugosa)
PF00135
(COesterase)
4 ILE A 453
TYR A 467
PHE A 471
PHE A 434
None
1.05A 1e71M-1crlA:
1.1
1e71M-1crlA:
21.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1dwa MYROSINASE MA1

(Sinapis alba)
PF00232
(Glyco_hydro_1)
7 GLN M 187
ILE M 257
ARG M 259
TYR M 330
PHE M 331
PHE M 371
PHE M 473
GOL  M 936 (-3.6A)
None
SO4  M 926 ( 2.9A)
None
None
None
None
0.07A 1e71M-1dwaM:
70.9
1e71M-1dwaM:
99.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f34 MAJOR PEPSIN
INHIBITOR PI-3


(Ascaris suum)
PF06394
(Pepsin-I3)
4 GLN B 105
PHE B   4
PHE B  76
PHE B 145
None
1.16A 1e71M-1f34B:
undetectable
1e71M-1f34B:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fnn CELL DIVISION
CONTROL PROTEIN 6


(Pyrobaculum
aerophilum)
PF09079
(Cdc6_C)
PF13401
(AAA_22)
4 ILE A  99
PHE A 111
PHE A  86
PHE A 144
None
1.12A 1e71M-1fnnA:
0.4
1e71M-1fnnA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fpq ISOLIQUIRITIGENIN
2'-O-METHYLTRANSFERA
SE


(Medicago sativa)
PF00891
(Methyltransf_2)
PF08100
(Dimerisation)
4 ILE A 308
TYR A 343
PHE A 355
PHE A 370
None
1.24A 1e71M-1fpqA:
undetectable
1e71M-1fpqA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gz7 LIPASE 2

(Diutina rugosa)
PF00135
(COesterase)
4 ILE A 453
TYR A 467
PHE A 471
PHE A 434
None
1.04A 1e71M-1gz7A:
1.1
1e71M-1gz7A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h3g CYCLOMALTODEXTRINASE

(Flavobacterium
sp. 92)
PF00128
(Alpha-amylase)
PF09087
(Cyc-maltodext_N)
PF10438
(Cyc-maltodext_C)
4 ILE A 297
ARG A 327
TYR A 324
PHE A 320
None
1.16A 1e71M-1h3gA:
6.7
1e71M-1h3gA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h54 MALTOSE
PHOSPHORYLASE


(Lactobacillus
brevis)
PF03632
(Glyco_hydro_65m)
PF03633
(Glyco_hydro_65C)
PF03636
(Glyco_hydro_65N)
4 ILE A  94
ARG A 128
PHE A 124
PHE A 137
None
1.25A 1e71M-1h54A:
undetectable
1e71M-1h54A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hn0 CHONDROITIN ABC
LYASE I


(Proteus
vulgaris)
PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF09092
(Lyase_N)
PF09093
(Lyase_catalyt)
4 ARG A 212
TYR A  42
PHE A  44
PHE A  53
None
1.25A 1e71M-1hn0A:
undetectable
1e71M-1hn0A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hn0 CHONDROITIN ABC
LYASE I


(Proteus
vulgaris)
PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF09092
(Lyase_N)
PF09093
(Lyase_catalyt)
4 ILE A 547
ARG A 634
TYR A 548
PHE A 510
None
1.23A 1e71M-1hn0A:
undetectable
1e71M-1hn0A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tdj BIOSYNTHETIC
THREONINE DEAMINASE


(Escherichia
coli)
PF00291
(PALP)
PF00585
(Thr_dehydrat_C)
4 GLN A  30
ARG A 100
PHE A  96
PHE A 124
None
1.21A 1e71M-1tdjA:
undetectable
1e71M-1tdjA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tp8 AGGLUTININ ALPHA
CHAIN


(Artocarpus
hirsutus)
PF01419
(Jacalin)
4 ILE A  65
PHE A 116
PHE A 127
PHE A 104
None
1.16A 1e71M-1tp8A:
undetectable
1e71M-1tp8A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ukr ENDO-1,4-B-XYLANASE
I


(Aspergillus
niger)
PF00457
(Glyco_hydro_11)
4 ILE A  82
TYR A  80
PHE A 157
PHE A 162
None
0.89A 1e71M-1ukrA:
undetectable
1e71M-1ukrA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1urd MALTOSE-BINDING
PROTEIN


(Alicyclobacillus
acidocaldarius)
PF01547
(SBP_bac_1)
4 GLN A 141
ILE A 288
PHE A  73
PHE A 180
MLR  A1400 (-3.1A)
None
MLR  A1400 (-4.6A)
None
1.14A 1e71M-1urdA:
undetectable
1e71M-1urdA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6


(Saccharomyces
cerevisiae)
PF00443
(UCH)
4 ILE A 433
PHE A 309
PHE A 233
PHE A 214
None
1.19A 1e71M-1vjvA:
undetectable
1e71M-1vjvA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ig3 GROUP III TRUNCATED
HAEMOGLOBIN


(Campylobacter
jejuni)
PF01152
(Bac_globin)
4 ILE A 113
PHE A  90
PHE A  18
PHE A  32
HEM  A 700 (-3.4A)
None
None
HEM  A 700 ( 3.8A)
1.14A 1e71M-2ig3A:
undetectable
1e71M-2ig3A:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iu5 HTH-TYPE DHAKLM
OPERON
TRANSCRIPTIONAL
ACTIVATOR DHAS


(Lactococcus
lactis)
PF00440
(TetR_N)
4 TYR A  93
PHE A  97
PHE A 103
PHE A  62
None
1.13A 1e71M-2iu5A:
undetectable
1e71M-2iu5A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qqz GLYOXALASE FAMILY
PROTEIN, PUTATIVE


(Bacillus
anthracis)
PF00903
(Glyoxalase)
4 ILE A  31
TYR A  27
PHE A  50
PHE A 112
None
1.15A 1e71M-2qqzA:
undetectable
1e71M-2qqzA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2reu TYPE II RESTRICTION
ENZYME SAU3AI


(Staphylococcus
aureus)
no annotation 4 ILE A 197
PHE A 143
PHE A 122
PHE A  89
None
1.21A 1e71M-2reuA:
undetectable
1e71M-2reuA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w0i TWINFILIN-2

(Homo sapiens)
PF00241
(Cofilin_ADF)
4 ILE A 212
TYR A 236
PHE A 238
PHE A 255
None
1.05A 1e71M-2w0iA:
undetectable
1e71M-2w0iA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w55 XANTHINE
DEHYDROGENASE


(Rhodobacter
capsulatus)
PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2)
4 ILE B 278
TYR B 276
PHE B 291
PHE B 166
None
1.15A 1e71M-2w55B:
undetectable
1e71M-2w55B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xij METHYLMALONYL-COA
MUTASE,
MITOCHONDRIAL


(Homo sapiens)
PF01642
(MM_CoA_mutase)
PF02310
(B12-binding)
4 ILE A 739
PHE A 643
PHE A 638
PHE A 722
None
None
B12  A 800 ( 4.9A)
B12  A 800 (-4.0A)
1.21A 1e71M-2xijA:
3.8
1e71M-2xijA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xt4 MCBG-LIKE PROTEIN

(Xanthomonas
albilineans)
PF00805
(Pentapeptide)
PF13599
(Pentapeptide_4)
4 ILE A  64
PHE A  76
PHE A 102
PHE A 112
None
1.07A 1e71M-2xt4A:
undetectable
1e71M-2xt4A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d1c FLAVIN-CONTAINING
PUTATIVE
MONOOXYGENASE


(Staphylococcus
aureus)
PF13738
(Pyr_redox_3)
4 ILE A  27
TYR A 133
PHE A 135
PHE A 303
None
1.22A 1e71M-3d1cA:
undetectable
1e71M-3d1cA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3daw TWINFILIN-1

(Mus musculus)
PF00241
(Cofilin_ADF)
4 ILE B 212
TYR B 236
PHE B 238
PHE B 255
None
1.04A 1e71M-3dawB:
undetectable
1e71M-3dawB:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dmc NTF2-LIKE PROTEIN

(Trichormus
variabilis)
PF12680
(SnoaL_2)
4 ARG A 123
TYR A 122
PHE A  40
PHE A  32
None
0.97A 1e71M-3dmcA:
undetectable
1e71M-3dmcA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0r C3-DEGRADING
PROTEINASE (CPPA
PROTEIN)


(Streptococcus
pneumoniae)
PF14506
(CppA_N)
PF14507
(CppA_C)
4 ILE A 169
PHE A 198
PHE A 238
PHE A 212
None
1.17A 1e71M-3e0rA:
undetectable
1e71M-3e0rA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ga1 NUCLEUS
ACCUMBENS-ASSOCIATED
PROTEIN 1


(Homo sapiens)
PF00651
(BTB)
4 ARG A  45
PHE A  59
PHE A  55
PHE A  78
None
1.20A 1e71M-3ga1A:
undetectable
1e71M-3ga1A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhd FATTY ACID SYNTHASE

(Homo sapiens)
PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc)
4 ILE A 834
TYR A  87
PHE A  65
PHE A 148
None
1.25A 1e71M-3hhdA:
undetectable
1e71M-3hhdA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i9f PUTATIVE TYPE 11
METHYLTRANSFERASE


(Sulfolobus
solfataricus)
PF08241
(Methyltransf_11)
4 ARG A 173
PHE A 154
PHE A 151
PHE A  95
None
1.11A 1e71M-3i9fA:
undetectable
1e71M-3i9fA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lkv UNCHARACTERIZED
CONSERVED DOMAIN
PROTEIN


(Vibrio cholerae)
PF04392
(ABC_sub_bind)
4 GLN A  34
ILE A  95
TYR A  67
PHE A  65
None
1.10A 1e71M-3lkvA:
undetectable
1e71M-3lkvA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lly AGGLUTININ ALPHA
CHAIN


(Maclura
pomifera)
PF01419
(Jacalin)
4 ILE A  65
PHE A 116
PHE A 127
PHE A 104
None
1.11A 1e71M-3llyA:
undetectable
1e71M-3llyA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mn8 LP15968P

(Drosophila
melanogaster)
PF00246
(Peptidase_M14)
PF13620
(CarboxypepD_reg)
4 ILE A 125
ARG A 124
TYR A 117
PHE A  34
None
1.05A 1e71M-3mn8A:
undetectable
1e71M-3mn8A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nhe UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2


(Homo sapiens)
PF00443
(UCH)
4 ILE A 411
PHE A 318
PHE A 339
PHE A 361
None
1.03A 1e71M-3nheA:
undetectable
1e71M-3nheA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p8s JACALIN

(Artocarpus
heterophyllus)
PF01419
(Jacalin)
4 ILE A  89
PHE A 140
PHE A 151
PHE A 128
None
1.09A 1e71M-3p8sA:
undetectable
1e71M-3p8sA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pqy ALPHA CHAIN OF THE
6218-TCR
BETA CHAIN OF THE
6218-TCR


(Homo sapiens;
Mus musculus;
Homo sapiens;
Mus musculus)
PF07686
(V-set)
PF09291
(DUF1968)
PF07654
(C1-set)
PF07686
(V-set)
4 ILE E  55
TYR E  42
PHE E 114
PHE D 116
None
1.23A 1e71M-3pqyE:
undetectable
1e71M-3pqyE:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qdn PUTATIVE THIOREDOXIN
PROTEIN


(Salmonella
enterica)
PF00085
(Thioredoxin)
PF14559
(TPR_19)
PF14561
(TPR_20)
4 GLN A  72
ILE A  69
PHE A  28
PHE A  84
None
1.20A 1e71M-3qdnA:
undetectable
1e71M-3qdnA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3umt SCFV HEAVY CHAIN AND
LIGHT CHAIN


(Mus musculus)
PF07686
(V-set)
4 GLN A 175
ILE A 181
TYR A 224
PHE A 235
None
1.12A 1e71M-3umtA:
undetectable
1e71M-3umtA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vrd FLAVOCYTOCHROME C
HEME SUBUNIT


(Thermochromatium
tepidum)
no annotation 4 GLN A  43
ILE A  49
ARG A 141
PHE A 136
HEC  A 202 ( 4.6A)
None
HEC  A 202 ( 3.0A)
HEC  A 202 (-4.5A)
1.20A 1e71M-3vrdA:
undetectable
1e71M-3vrdA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w8s GLUTATHIONE
S-TRANSFERASE-3


(Necator
americanus)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 ILE A 181
PHE A 132
PHE A  98
PHE A 125
None
1.14A 1e71M-3w8sA:
undetectable
1e71M-3w8sA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wev L-LYSINE 6-OXIDASE

(Marinomonas
mediterranea)
no annotation 4 GLN A 608
ARG A 614
PHE A 679
PHE A 657
None
0.98A 1e71M-3wevA:
undetectable
1e71M-3wevA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyv AOX3

(Mus musculus)
PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C)
4 ILE A 831
ARG A 829
TYR A 679
PHE A 611
None
1.08A 1e71M-3zyvA:
undetectable
1e71M-3zyvA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bb9 GLUCOKINASE
REGULATORY PROTEIN


(Homo sapiens)
no annotation 4 ILE A 552
ARG A 553
PHE A   7
PHE A 516
None
1.12A 1e71M-4bb9A:
undetectable
1e71M-4bb9A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dh2 CELLULOSOME
ANCHORING PROTEIN
COHESIN REGION


(Ruminiclostridium
thermocellum)
PF00963
(Cohesin)
4 ILE A  82
TYR A  80
PHE A  91
PHE A  78
None
1.15A 1e71M-4dh2A:
undetectable
1e71M-4dh2A:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ell RETINOBLASTOMA-ASSOC
IATED PROTEIN


(Homo sapiens)
PF01857
(RB_B)
PF01858
(RB_A)
4 ILE A 768
TYR A 756
PHE A 760
PHE A 721
None
1.20A 1e71M-4ellA:
undetectable
1e71M-4ellA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fbq DNA REPAIR AND
TELOMERE MAINTENANCE
PROTEIN NBS1,DNA
REPAIR PROTEIN RAD32
CHIMERIC PROTEIN


(Schizosaccharomyces
pombe)
PF00149
(Metallophos)
PF04152
(Mre11_DNA_bind)
4 ILE A1347
ARG A1399
PHE A1396
PHE A1392
None
1.25A 1e71M-4fbqA:
3.0
1e71M-4fbqA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fd7 PUTATIVE
ARYLALKYLAMINE
N-ACETYLTRANSFERASE
7


(Aedes aegypti)
PF00583
(Acetyltransf_1)
4 ILE A 129
TYR A 126
PHE A 122
PHE A 117
None
0.95A 1e71M-4fd7A:
undetectable
1e71M-4fd7A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fdh CYTOCHROME P450
11B2, MITOCHONDRIAL


(Homo sapiens)
PF00067
(p450)
4 ILE A 263
PHE A 231
PHE A 487
PHE A 130
None
0T3  A 602 ( 4.9A)
0T3  A 602 (-4.8A)
0T3  A 602 (-4.0A)
1.26A 1e71M-4fdhA:
undetectable
1e71M-4fdhA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gd5 PHOSPHATE ABC
TRANSPORTER,
PHOSPHATE-BINDING
PROTEIN


(Clostridium
perfringens)
PF12849
(PBP_like_2)
4 ILE A 150
TYR A 133
PHE A 171
PHE A 165
None
1.16A 1e71M-4gd5A:
undetectable
1e71M-4gd5A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h7u PYRANOSE
DEHYDROGENASE


(Leucoagaricus
meleagris)
PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C)
4 ILE A 133
TYR A 567
PHE A 564
PHE A 533
None
1.00A 1e71M-4h7uA:
undetectable
1e71M-4h7uA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hoi POTASSIUM
VOLTAGE-GATED
CHANNEL SUBFAMILY H
MEMBER 1


(Mus musculus)
PF13426
(PAS_9)
4 ILE A  97
PHE A 130
PHE A  49
PHE A  69
None
1.02A 1e71M-4hoiA:
undetectable
1e71M-4hoiA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4llo POTASSIUM
VOLTAGE-GATED
CHANNEL SUBFAMILY H
MEMBER 1


(Mus musculus)
PF13426
(PAS_9)
4 ILE B  97
PHE B 130
PHE B  49
PHE B  69
None
1.09A 1e71M-4lloB:
undetectable
1e71M-4lloB:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pzk TRNA
(CYTIDINE(34)-2'-O)-
METHYLTRANSFERASE


(Bacillus
anthracis)
PF00588
(SpoU_methylase)
4 GLN A 151
TYR A  99
PHE A 101
PHE A  77
None
1.21A 1e71M-4pzkA:
undetectable
1e71M-4pzkA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q8r PHOSPHATE ABC
TRANSPORTER,
PHOSPHATE-BINDING
PROTEIN


(Clostridium
perfringens)
PF12849
(PBP_like_2)
4 ILE A 120
TYR A 103
PHE A 141
PHE A 135
None
1.13A 1e71M-4q8rA:
undetectable
1e71M-4q8rA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r86 RND FAMILY
AMINOGLYCOSIDE/MULTI
DRUG EFFLUX PUMP


(Salmonella
enterica)
PF00873
(ACR_tran)
4 ILE A 291
TYR A 289
PHE A 108
PHE A 283
None
1.17A 1e71M-4r86A:
undetectable
1e71M-4r86A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w79 PROTEIN N-TERMINAL
GLUTAMINE
AMIDOHYDROLASE


(Homo sapiens)
PF09764
(Nt_Gln_amidase)
4 ILE A  64
ARG A 128
PHE A 196
PHE A 108
None
1.23A 1e71M-4w79A:
undetectable
1e71M-4w79A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xly UNCHARACTERIZED
PROTEIN BLR2150


(Bradyrhizobium
diazoefficiens)
no annotation 4 GLN A 206
ILE A 202
TYR A 168
PHE A 172
None
1.15A 1e71M-4xlyA:
undetectable
1e71M-4xlyA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yji ARYL ACYLAMIDASE

(bacterium
CSBL00001)
PF01425
(Amidase)
4 ILE A 360
TYR A 136
PHE A 138
PHE A  87
None
0.99A 1e71M-4yjiA:
undetectable
1e71M-4yjiA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z7e LMO1422 PROTEIN

(Listeria
monocytogenes)
PF04069
(OpuAC)
4 TYR A 381
PHE A 374
PHE A 370
PHE A 392
None
1.22A 1e71M-4z7eA:
undetectable
1e71M-4z7eA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a2o NITRATE TRANSPORTER
1.1


(Arabidopsis
thaliana)
PF00854
(PTR2)
4 ARG A 243
TYR A 242
PHE A 170
PHE A 235
None
1.02A 1e71M-5a2oA:
undetectable
1e71M-5a2oA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE


(Thymus vulgaris)
PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C)
4 ILE A 204
ARG A 161
PHE A 157
PHE A 183
ILE  A 204 ( 0.7A)
ARG  A 161 (-0.6A)
PHE  A 157 ( 1.3A)
PHE  A 183 ( 1.3A)
1.09A 1e71M-5c05A:
undetectable
1e71M-5c05A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cs4 ACETYL-COA
CARBOXYLASE


(Saccharomyces
cerevisiae)
PF08326
(ACC_central)
4 ILE A1385
PHE A1407
PHE A1404
PHE A1389
None
1.14A 1e71M-5cs4A:
undetectable
1e71M-5cs4A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5csa ACETYL-COA
CARBOXYLASE


(Saccharomyces
cerevisiae)
PF00364
(Biotin_lipoyl)
PF08326
(ACC_central)
4 ILE A1385
PHE A1407
PHE A1404
PHE A1389
None
1.08A 1e71M-5csaA:
undetectable
1e71M-5csaA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dqs ELONGATION FACTOR
1-GAMMA


(Homo sapiens)
PF00043
(GST_C)
PF02798
(GST_N)
4 ILE A  75
PHE A  53
PHE A  49
PHE A  40
None
0.98A 1e71M-5dqsA:
undetectable
1e71M-5dqsA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5du9 CDA PEPTIDE
SYNTHETASE I


(Streptomyces
coelicolor)
PF00668
(Condensation)
4 ILE A 384
ARG A 382
TYR A 152
PHE A 142
None
1.19A 1e71M-5du9A:
undetectable
1e71M-5du9A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fof LEUCYL-TRNA
SYNTHETASE


(Plasmodium
knowlesi)
no annotation 4 ILE A 411
TYR A 287
PHE A 283
PHE A 309
None
1.07A 1e71M-5fofA:
undetectable
1e71M-5fofA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h82 HETEROYOHIMBINE
SYNTHASE THAS2


(Catharanthus
roseus)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 ILE A 152
ARG A  30
TYR A  12
PHE A  28
None
0.98A 1e71M-5h82A:
undetectable
1e71M-5h82A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6e ACETYL-COA
CARBOXYLASE


(Saccharomyces
cerevisiae)
PF08326
(ACC_central)
4 ILE A1385
PHE A1407
PHE A1404
PHE A1389
None
1.19A 1e71M-5i6eA:
undetectable
1e71M-5i6eA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5irm UNCHARACTERIZED
PROTEIN


(Oryctolagus
cuniculus)
PF05729
(NACHT)
PF13516
(LRR_6)
4 ILE A 497
TYR A 494
PHE A 589
PHE A 657
None
1.20A 1e71M-5irmA:
undetectable
1e71M-5irmA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j68 ASTROTACTIN-2

(Homo sapiens)
PF01823
(MACPF)
4 GLN A 773
TYR A 813
PHE A 723
PHE A 756
None
1.04A 1e71M-5j68A:
undetectable
1e71M-5j68A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j69 ASTROTACTIN-2

(Homo sapiens)
PF01823
(MACPF)
4 GLN A 773
TYR A 813
PHE A 723
PHE A 756
None
1.04A 1e71M-5j69A:
undetectable
1e71M-5j69A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7


(Homo sapiens)
PF00443
(UCH)
PF12436
(USP7_ICP0_bdg)
4 GLN A 880
TYR A 878
PHE A 839
PHE A 809
None
0.97A 1e71M-5j7tA:
undetectable
1e71M-5j7tA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k7l POTASSIUM
VOLTAGE-GATED
CHANNEL SUBFAMILY H
MEMBER 1


(Rattus
norvegicus)
PF00027
(cNMP_binding)
PF00520
(Ion_trans)
PF13426
(PAS_9)
4 ILE A  97
PHE A 130
PHE A  49
PHE A  69
None
1.08A 1e71M-5k7lA:
undetectable
1e71M-5k7lA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ldd RAB SMALL MONOMERIC
GTPASE-LIKE PROTEIN


(Chaetomium
thermophilum)
PF00071
(Ras)
4 ARG C  69
PHE C  70
PHE C  77
PHE C  45
None
1.25A 1e71M-5lddC:
undetectable
1e71M-5lddC:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lw6 DDB_G0293866

(Dictyostelium
discoideum)
no annotation 4 ILE A  42
TYR A 211
PHE A 215
PHE A  24
None
1.01A 1e71M-5lw6A:
undetectable
1e71M-5lw6A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lxd DUAL SPECIFICITY
TYROSINE-PHOSPHORYLA
TION-REGULATED
KINASE 2


(Homo sapiens)
PF00069
(Pkinase)
4 GLN A 139
ARG A 221
PHE A 220
PHE A 218
None
0.91A 1e71M-5lxdA:
undetectable
1e71M-5lxdA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m22 HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT


(Sphingomonas
sp. TTNP3)
no annotation 4 ILE A 108
TYR A 137
PHE A 139
PHE A 149
None
1.07A 1e71M-5m22A:
undetectable
1e71M-5m22A:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m2o PUTATIVE
CELLULOSOMAL
SCAFFOLDIN PROTEIN
GROUP I DOCKERIN


(Ruminococcus
flavefaciens;
Ruminococcus
flavefaciens)
PF00963
(Cohesin)
no annotation
4 ILE B  39
PHE A  76
PHE A  95
PHE A 114
None
0.98A 1e71M-5m2oB:
undetectable
1e71M-5m2oB:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5me3 SISTER CHROMATID
COHESION PROTEIN 2


(Eremothecium
gossypii)
PF12765
(Cohesin_HEAT)
PF12830
(Nipped-B_C)
4 ILE A 884
PHE A 865
PHE A 862
PHE A 921
None
1.05A 1e71M-5me3A:
undetectable
1e71M-5me3A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE


(Bacteroides
thetaiotaomicron)
PF07944
(Glyco_hydro_127)
4 ILE A 330
TYR A 304
PHE A 391
PHE A 287
None
1.00A 1e71M-5mqoA:
undetectable
1e71M-5mqoA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5my0 FATTY ACID SYNTHASE

(Mus musculus)
no annotation 4 ILE B 834
TYR B  87
PHE B  65
PHE B 148
None
1.26A 1e71M-5my0B:
undetectable
1e71M-5my0B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5svc ACETONE CARBOXYLASE
ALPHA SUBUNIT


(Xanthobacter
autotrophicus)
PF02538
(Hydantoinase_B)
4 ILE A 599
ARG A 601
PHE A 536
PHE A 612
None
1.06A 1e71M-5svcA:
undetectable
1e71M-5svcA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5td6 FOG-3 PROTEIN

(Caenorhabditis
elegans)
PF07742
(BTG)
4 ILE A  89
ARG A 100
PHE A  98
PHE A  40
None
1.24A 1e71M-5td6A:
undetectable
1e71M-5td6A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u4o ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN


(Bacillus
anthracis)
PF00496
(SBP_bac_5)
4 ILE A 308
PHE A 288
PHE A 295
PHE A 363
None
0.95A 1e71M-5u4oA:
undetectable
1e71M-5u4oA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u4o ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN


(Bacillus
anthracis)
PF00496
(SBP_bac_5)
4 ILE A 382
PHE A 288
PHE A 295
PHE A 363
None
0.94A 1e71M-5u4oA:
undetectable
1e71M-5u4oA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vld HISTIDINOL
DEHYDROGENASE,
CHLOROPLASTIC


(Medicago
truncatula)
PF00815
(Histidinol_dh)
4 ARG A 417
TYR A 364
PHE A 360
PHE A 347
None
1.22A 1e71M-5vldA:
undetectable
1e71M-5vldA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wkh T-CELL RECEPTOR
ALPHA VARIABLE
30,T-CELL RECEPTOR,
SP3.4 ALPHA CHAIN
D30 TCR BETA CHAIN


(Homo sapiens;
Homo sapiens)
PF07686
(V-set)
PF09291
(DUF1968)
no annotation
4 ILE D  55
TYR D  42
PHE D 112
PHE E 121
None
1.12A 1e71M-5wkhD:
undetectable
1e71M-5wkhD:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wp6 TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY M
MEMBER 4


(Homo sapiens)
no annotation 4 ILE A1066
ARG A1062
TYR A1063
PHE A 667
None
0.92A 1e71M-5wp6A:
undetectable
1e71M-5wp6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wtk CRISPR-ASSOCIATED
ENDORIBONUCLEASE
C2C2


(Leptotrichia
shahii)
no annotation 4 ILE A 532
PHE A 585
PHE A 589
PHE A 843
None
1.03A 1e71M-5wtkA:
undetectable
1e71M-5wtkA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b3y DENN
DOMAIN-CONTAINING
PROTEIN 3


(Mus musculus)
no annotation 4 TYR A 775
PHE A 774
PHE A 771
PHE A 723
None
0.95A 1e71M-6b3yA:
undetectable
1e71M-6b3yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bfu SPIKE PROTEIN

(Coronavirus
HKU15)
no annotation 4 GLN A 923
ILE A 676
PHE A 782
PHE A 919
None
1.18A 1e71M-6bfuA:
undetectable
1e71M-6bfuA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bv2 AMINOPEPTIDASE N

(Sus scrofa)
no annotation 4 ILE A 430
TYR A 411
PHE A 408
PHE A 491
None
SO4  A1030 (-4.6A)
None
None
1.21A 1e71M-6bv2A:
undetectable
1e71M-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bxn DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2


(Candidatus
Methanoperedens
nitroreducens)
no annotation 4 GLN A 302
ARG A 214
PHE A 210
PHE A 161
None
1.11A 1e71M-6bxnA:
undetectable
1e71M-6bxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eti ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2


(Homo sapiens)
no annotation 4 ILE A 335
TYR A 282
PHE A 277
PHE A 293
None
1.26A 1e71M-6etiA:
undetectable
1e71M-6etiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fb3 TENEURIN-2

(Gallus gallus)
no annotation 4 GLN A2455
PHE A2297
PHE A2039
PHE A2026
None
1.20A 1e71M-6fb3A:
undetectable
1e71M-6fb3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fn1 HUMAN-MOUSE CHIMERIC
ABCB1 (ABCBHM)


(Homo sapiens)
no annotation 4 ILE A1120
ARG A1187
PHE A 266
PHE A1085
None
1.17A 1e71M-6fn1A:
undetectable
1e71M-6fn1A:
undetectable