SIMILAR PATTERNS OF AMINO ACIDS FOR 1E06_B_IPBB600

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1a3y ODORANT BINDING
PROTEIN

(Sus scrofa) 		PF00061
(Lipocalin) 		4 ILE A  21
MET A  39
VAL A  80
GLY A 116
 None
 0.29A 1e06B-1a3yA:
29.3		 1e06B-1a3yA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bam ENDONUCLEASE BAMH I

(Bacillus
amyloliquefaciens) 		PF02923
(BamHI) 		4 ILE A 177
MET A   1
VAL A  57
GLY A 178
 None
 1.29A 1e06B-1bamA:
0.0		 1e06B-1bamA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c7g TYROSINE
PHENOL-LYASE

(Pantoea
agglomerans) 		PF01212
(Beta_elim_lyase) 		4 ILE A  43
MET A  28
VAL A 403
GLY A 375
 None
 1.31A 1e06B-1c7gA:
undetectable		 1e06B-1c7gA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f07 COENZYME
F420-DEPENDENT
N5,N10-METHYLENETETR
AHYDROMETHANOPTERIN
REDUCTASE

(Methanothermobacter
thermautotrophicus) 		PF00296
(Bac_luciferase) 		4 ILE A 185
MET A 157
VAL A  62
GLY A 162
 None
None
MPO  A 331 (-3.9A)
None
 1.05A 1e06B-1f07A:
0.0		 1e06B-1f07A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nhc POLYGALACTURONASE I

(Aspergillus
niger) 		PF00295
(Glyco_hydro_28) 		4 ILE A 172
MET A 135
VAL A 165
GLY A 187
 None
 1.44A 1e06B-1nhcA:
0.0		 1e06B-1nhcA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nxk MAP KINASE-ACTIVATED
PROTEIN KINASE 2

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE A 170
MET A 253
VAL A 331
GLY A 171
 None
 1.31A 1e06B-1nxkA:
0.4		 1e06B-1nxkA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ou0 PRECORRIN-8X
METHYLMUTASE RELATED
PROTEIN

(Thermoplasma
acidophilum) 		PF02570
(CbiC) 		4 ILE A  36
MET A  63
VAL A  80
GLY A 201
 None
 1.40A 1e06B-1ou0A:
undetectable		 1e06B-1ou0A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qyd PINORESINOL-LARICIRE
SINOL REDUCTASE

(Thuja plicata) 		PF05368
(NmrA) 		4 ILE A 226
MET A 305
VAL A 200
GLY A 192
 None
 1.24A 1e06B-1qydA:
0.0		 1e06B-1qydA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s4v CYSTEINE
ENDOPEPTIDASE

(Ricinus
communis) 		PF00112
(Peptidase_C1) 		4 ILE A 201
MET A 197
VAL A 128
GLY A 206
 None
 1.27A 1e06B-1s4vA:
0.4		 1e06B-1s4vA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1skx ORPHAN NUCLEAR
RECEPTOR PXR

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 ILE A 254
MET A 246
VAL A 291
GLY A 253
 None
 1.21A 1e06B-1skxA:
undetectable		 1e06B-1skxA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sq1 CHORISMATE SYNTHASE

(Campylobacter
jejuni) 		PF01264
(Chorismate_synt) 		4 ILE A 287
MET A 214
VAL A 339
GLY A 274
 None
 1.42A 1e06B-1sq1A:
undetectable		 1e06B-1sq1A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v5f PYRUVATE OXIDASE

(Aerococcus
viridans) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 ILE A 102
MET A  36
VAL A  51
GLY A 104
 None
 1.29A 1e06B-1v5fA:
undetectable		 1e06B-1v5fA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vq0 33 KDA CHAPERONIN

(Thermotoga
maritima) 		PF01430
(HSP33) 		4 ILE A 198
MET A  19
VAL A  50
GLY A 157
 None
 1.24A 1e06B-1vq0A:
undetectable		 1e06B-1vq0A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w4s POLYBROMO 1 PROTEIN

(Gallus gallus) 		PF01426
(BAH) 		4 ILE A 978
MET A1076
VAL A1015
GLY A 993
 None
 1.11A 1e06B-1w4sA:
undetectable		 1e06B-1w4sA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xdw NAD+-DEPENDENT
(R)-2-HYDROXYGLUTARA
TE DEHYDROGENASE

(Acidaminococcus
fermentans) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 ILE A 201
MET A 224
VAL A 239
GLY A 150
 None
 1.35A 1e06B-1xdwA:
undetectable		 1e06B-1xdwA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xtt PROBABLE URACIL
PHOSPHORIBOSYLTRANSF
ERASE

(Sulfolobus
solfataricus) 		PF14681
(UPRTase) 		4 ILE A 121
MET A 149
VAL A 136
GLY A 102
 None
 1.28A 1e06B-1xttA:
undetectable		 1e06B-1xttA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z69 COENZYME
F420-DEPENDENT
N(5),N(10)-METHYLENE
TETRAHYDROMETHANOPTE
RIN REDUCTASE

(Methanosarcina
barkeri) 		PF00296
(Bac_luciferase) 		4 ILE A 190
MET A 162
VAL A  62
GLY A 167
 None
F42  A 328 (-4.7A)
F42  A 328 (-4.4A)
None
 1.08A 1e06B-1z69A:
undetectable		 1e06B-1z69A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zjj HYPOTHETICAL PROTEIN
PH1952

(Pyrococcus
horikoshii) 		PF13242
(Hydrolase_like)
PF13344
(Hydrolase_6) 		4 ILE A 183
MET A  77
VAL A 119
GLY A 150
 None
 1.32A 1e06B-1zjjA:
undetectable		 1e06B-1zjjA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a5j RAS-RELATED PROTEIN
RAB-2B

(Homo sapiens) 		PF00071
(Ras) 		4 ILE A  64
MET A  52
VAL A   5
GLY A  49
 None
 1.21A 1e06B-2a5jA:
undetectable		 1e06B-2a5jA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ay9 AROMATIC AMINO ACID
AMINOTRANSFERASE

(Paracoccus
denitrificans) 		PF00155
(Aminotran_1_2) 		4 ILE A  33
MET A 381
VAL A 409
GLY A 378
 None
 1.22A 1e06B-2ay9A:
undetectable		 1e06B-2ay9A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b9l PROPHENOLOXIDASE
ACTIVATING FACTOR

(Holotrichia
diomphalia) 		PF00089
(Trypsin) 		4 ILE A  29
MET A  24
VAL A 194
GLY A  31
 None
None
None
NAG  A 416 ( 4.6A)
 1.30A 1e06B-2b9lA:
undetectable		 1e06B-2b9lA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dw4 LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1

(Homo sapiens) 		PF01593
(Amino_oxidase)
PF04433
(SWIRM) 		4 ILE A 266
MET A 342
VAL A 317
GLY A 265
 None
 1.35A 1e06B-2dw4A:
undetectable		 1e06B-2dw4A:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fa0 HMG-COA SYNTHASE

(Brassica juncea) 		PF01154
(HMG_CoA_synt_N)
PF08540
(HMG_CoA_synt_C) 		4 ILE A 169
MET A  10
VAL A 245
GLY A   6
 None
 1.12A 1e06B-2fa0A:
undetectable		 1e06B-2fa0A:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fom POLYPROTEIN

(Dengue virus) 		PF00949
(Peptidase_S7) 		4 ILE B  25
MET B  49
VAL B 146
GLY B  37
 None
None
CL  B 201 (-4.1A)
None
 1.17A 1e06B-2fomB:
undetectable		 1e06B-2fomB:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iir ACETATE KINASE

(Thermotoga
maritima) 		PF00871
(Acetate_kinase) 		4 ILE A   6
MET A 134
VAL A 108
GLY A 129
 None
 1.37A 1e06B-2iirA:
undetectable		 1e06B-2iirA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2isq CYSTEINE SYNTHASE

(Arabidopsis
thaliana) 		PF00291
(PALP) 		4 ILE A 268
MET A 254
VAL A 177
GLY A 267
 None
 0.95A 1e06B-2isqA:
undetectable		 1e06B-2isqA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE

(Elizabethkingia
meningoseptica) 		PF01408
(GFO_IDH_MocA) 		4 ILE A 295
MET A 236
VAL A 151
GLY A 175
 None
None
A2G  A1446 (-4.9A)
None
 1.35A 1e06B-2ixbA:
undetectable		 1e06B-2ixbA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l6x GREEN-LIGHT
ABSORBING
PROTEORHODOPSIN

(uncultured
marine gamma
proteobacterium
EBAC31A08) 		PF01036
(Bac_rhodopsin) 		4 ILE A 194
MET A 189
VAL A 102
GLY A 196
 None
 1.43A 1e06B-2l6xA:
undetectable		 1e06B-2l6xA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p1n SKP1-LIKE PROTEIN 1A

(Arabidopsis
thaliana) 		PF01466
(Skp1)
PF03931
(Skp1_POZ) 		4 ILE A   6
MET A  32
VAL A  47
GLY A  41
 None
 1.13A 1e06B-2p1nA:
undetectable		 1e06B-2p1nA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p3g MAP KINASE-ACTIVATED
PROTEIN KINASE 2

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE X 170
MET X 253
VAL X 331
GLY X 171
 None
 1.16A 1e06B-2p3gX:
undetectable		 1e06B-2p3gX:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pgw MUCONATE
CYCLOISOMERASE

(Sinorhizobium
meliloti) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ILE A 270
MET A 282
VAL A 137
GLY A 271
 None
 1.26A 1e06B-2pgwA:
undetectable		 1e06B-2pgwA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qby CELL DIVISION
CONTROL PROTEIN 6
HOMOLOG 3

(Sulfolobus
solfataricus) 		PF09079
(Cdc6_C)
PF13401
(AAA_22) 		4 ILE B 163
MET B 190
VAL B 177
GLY B 161
 None
 1.32A 1e06B-2qbyB:
undetectable		 1e06B-2qbyB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2whx SERINE
PROTEASE/NTPASE/HELI
CASE NS3

(Dengue virus) 		PF00949
(Peptidase_S7)
PF07652
(Flavi_DEAD) 		4 ILE A  25
MET A  49
VAL A 146
GLY A  37
 None
 1.31A 1e06B-2whxA:
undetectable		 1e06B-2whxA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x5d PROBABLE
AMINOTRANSFERASE

(Pseudomonas
aeruginosa) 		PF00155
(Aminotran_1_2) 		4 ILE A 141
MET A 115
VAL A 127
GLY A 143
 None
 1.40A 1e06B-2x5dA:
undetectable		 1e06B-2x5dA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xhg TYROCIDINE
SYNTHETASE A

(Brevibacillus
brevis) 		PF00668
(Condensation) 		4 ILE A 174
MET A  58
VAL A 302
GLY A 164
 None
 1.11A 1e06B-2xhgA:
undetectable		 1e06B-2xhgA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yq4 D-ISOMER SPECIFIC
2-HYDROXYACID
DEHYDROGENASE

(Lactobacillus
delbrueckii) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 ILE A 203
MET A 226
VAL A 241
GLY A 152
 None
 1.28A 1e06B-2yq4A:
undetectable		 1e06B-2yq4A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zc7 BETA-LACTAMASE ACT-1

(Klebsiella
pneumoniae) 		PF00144
(Beta-lactamase) 		4 ILE A  65
MET A 338
VAL A 283
GLY A 317
 None
 1.01A 1e06B-2zc7A:
undetectable		 1e06B-2zc7A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zkm 1-PHOSPHATIDYLINOSIT
OL-4,5-BISPHOSPHATE
PHOSPHODIESTERASE
BETA-2

(Homo sapiens) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		4 ILE X 371
MET X 420
VAL X 536
GLY X 363
 None
 1.34A 1e06B-2zkmX:
undetectable		 1e06B-2zkmX:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3awd PUTATIVE POLYOL
DEHYDROGENASE

(Gluconobacter
oxydans) 		PF13561
(adh_short_C2) 		4 ILE A  39
MET A  66
VAL A 130
GLY A  18
 None
 1.31A 1e06B-3awdA:
undetectable		 1e06B-3awdA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cb5 FACT COMPLEX SUBUNIT
SPT16

(Schizosaccharomyces
pombe) 		PF00557
(Peptidase_M24)
PF14826
(FACT-Spt16_Nlob) 		4 ILE A 184
MET A 383
VAL A 371
GLY A 361
 None
 1.30A 1e06B-3cb5A:
undetectable		 1e06B-3cb5A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ebw PER A 4 ALLERGEN

(Periplaneta
americana) 		PF08212
(Lipocalin_2) 		4 ILE A   8
MET A  99
VAL A 140
GLY A 112
 None
 1.38A 1e06B-3ebwA:
10.5		 1e06B-3ebwA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fwx PEPTIDE DEFORMYLASE

(Vibrio cholerae) 		PF01327
(Pep_deformylase) 		4 ILE A  45
MET A  71
VAL A 107
GLY A  46
 None
 1.23A 1e06B-3fwxA:
undetectable		 1e06B-3fwxA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwq D-SERINE DEAMINASE

(Paraburkholderia
xenovorans) 		PF01168
(Ala_racemase_N)
PF14031
(D-ser_dehydrat) 		4 ILE A 329
MET A 390
VAL A  49
GLY A 330
 None
 1.20A 1e06B-3gwqA:
undetectable		 1e06B-3gwqA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hzu THIOSULFATE
SULFURTRANSFERASE
SSEA

(Mycobacterium
tuberculosis) 		PF00581
(Rhodanese) 		4 ILE A  73
MET A  82
VAL A 119
GLY A  75
 None
 1.44A 1e06B-3hzuA:
undetectable		 1e06B-3hzuA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k2w BETAINE-ALDEHYDE
DEHYDROGENASE

(Pseudoalteromonas
atlantica) 		PF00171
(Aldedh) 		4 ILE A  30
MET A  93
VAL A 208
GLY A  40
 None
 1.29A 1e06B-3k2wA:
undetectable		 1e06B-3k2wA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k4h PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Bacillus
cytotoxicus) 		PF13377
(Peripla_BP_3) 		4 ILE A 137
MET A 187
VAL A 218
GLY A 179
 None
 1.42A 1e06B-3k4hA:
undetectable		 1e06B-3k4hA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k92 NAD-SPECIFIC
GLUTAMATE
DEHYDROGENASE

(Bacillus
subtilis) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 ILE A 250
MET A 240
VAL A 322
GLY A 249
 None
 1.15A 1e06B-3k92A:
undetectable		 1e06B-3k92A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ksd GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1

(Staphylococcus
aureus) 		no annotation 4 ILE Q  13
MET Q 318
VAL Q  24
GLY Q  14
 NAD  Q 337 (-4.4A)
None
None
None
 1.38A 1e06B-3ksdQ:
undetectable		 1e06B-3ksdQ:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3laq UROKINASE
PLASMINOGEN
ACTIVATOR SURFACE
RECEPTOR

(Mus musculus) 		PF00021
(UPAR_LY6) 		4 ILE U 211
MET U 217
VAL U 127
GLY U 238
 None
 1.21A 1e06B-3laqU:
undetectable		 1e06B-3laqU:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lme POSSIBLE TRANSLATION
INITIATION INHIBITOR

(Rhodopseudomonas
palustris) 		PF01042
(Ribonuc_L-PSP) 		4 ILE A  32
MET A  85
VAL A 100
GLY A  48
 None
 1.26A 1e06B-3lmeA:
undetectable		 1e06B-3lmeA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nm1 THIAMINE
BIOSYNTHETIC
BIFUNCTIONAL ENZYME

([Candida]
glabrata) 		PF02110
(HK)
PF02581
(TMP-TENI) 		4 ILE A 179
MET A 154
VAL A 121
GLY A 178
 IFP  A 542 (-3.8A)
None
None
None
 1.14A 1e06B-3nm1A:
undetectable		 1e06B-3nm1A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ntd FAD-DEPENDENT
PYRIDINE
NUCLEOTIDE-DISULPHID
E OXIDOREDUCTASE

(Shewanella
loihica) 		PF00581
(Rhodanese)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 ILE A 419
MET A 426
VAL A 378
GLY A 359
 None
 1.23A 1e06B-3ntdA:
undetectable		 1e06B-3ntdA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3odm PHOSPHOENOLPYRUVATE
CARBOXYLASE

(Clostridium
perfringens) 		PF14010
(PEPcase_2) 		4 ILE A 338
MET A 529
VAL A 451
GLY A 396
 None
 1.19A 1e06B-3odmA:
undetectable		 1e06B-3odmA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p24 BFT-3

(Bacteroides
fragilis) 		PF13583
(Reprolysin_4)
PF16376
(fragilysinNterm) 		4 ILE A 353
MET A 346
VAL A 263
GLY A 334
 None
 1.36A 1e06B-3p24A:
3.1		 1e06B-3p24A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3psh PROTEIN HI_1472

(Haemophilus
influenzae) 		PF01497
(Peripla_BP_2) 		4 ILE A 165
MET A 303
VAL A  44
GLY A 164
 None
 1.41A 1e06B-3pshA:
undetectable		 1e06B-3pshA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II

(Bacillus
anthracis) 		PF01116
(F_bP_aldolase) 		4 ILE A  46
MET A 105
VAL A 141
GLY A  48
 None
 1.21A 1e06B-3q94A:
undetectable		 1e06B-3q94A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3she MAP KINASE-ACTIVATED
PROTEIN KINASE 3

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE A 150
MET A 232
VAL A 310
GLY A 151
 None
 1.30A 1e06B-3sheA:
undetectable		 1e06B-3sheA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN

(Shewanella
pealeana) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ILE A 100
MET A  86
VAL A  30
GLY A  99
 None
 1.11A 1e06B-3sjnA:
undetectable		 1e06B-3sjnA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sx2 PUTATIVE
3-KETOACYL-(ACYL-CAR
RIER-PROTEIN)
REDUCTASE

(Mycobacterium
avium) 		PF13561
(adh_short_C2) 		4 ILE A 211
MET A 233
VAL A 174
GLY A 205
 NAD  A 300 (-3.8A)
None
None
NAD  A 300 (-3.3A)
 1.42A 1e06B-3sx2A:
undetectable		 1e06B-3sx2A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u1j SERINE PROTEASE NS3

(Dengue virus) 		PF00949
(Peptidase_S7) 		4 ILE B  25
MET B  49
VAL B 146
GLY B  37
 None
 1.29A 1e06B-3u1jB:
undetectable		 1e06B-3u1jB:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3upy OXIDOREDUCTASE

(Brucella
abortus) 		PF03447
(NAD_binding_3) 		4 ILE A  29
MET A 138
VAL A  42
GLY A  30
 None
 1.19A 1e06B-3upyA:
undetectable		 1e06B-3upyA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wwz D-LACTATE
DEHYDROGENASE
(FERMENTATIVE)

(Pseudomonas
aeruginosa) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 ILE A 200
MET A 223
VAL A 238
GLY A 148
 None
 1.41A 1e06B-3wwzA:
undetectable		 1e06B-3wwzA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a35 MITOCHONDRIAL
ENOLASE SUPERFAMILY
MEMBER 1

(Homo sapiens) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ILE A 305
MET A 268
VAL A 225
GLY A 304
 None
 1.19A 1e06B-4a35A:
undetectable		 1e06B-4a35A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b2q ATP SYNTHASE SUBUNIT
BETA, MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		4 ILE D 344
MET D 459
VAL D 165
GLY D 343
 None
None
ADP  D1476 (-4.2A)
None
 1.14A 1e06B-4b2qD:
undetectable		 1e06B-4b2qD:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4be9 STEROL ESTERASE

(Ophiostoma
piceae) 		PF00135
(COesterase) 		4 ILE A 216
MET A 250
VAL A 334
GLY A 247
 None
 1.17A 1e06B-4be9A:
undetectable		 1e06B-4be9A:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ep0 MAJOR TAIL PROTEIN

(Streptococcus
virus C1) 		PF16838
(Caud_tail_N) 		4 ILE A 531
MET A 542
VAL A 120
GLY A 530
 None
 1.19A 1e06B-4ep0A:
undetectable		 1e06B-4ep0A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4isb LONG CHAIN FATTY
ACID COA LIGASE
FADD10

(Mycobacterium
tuberculosis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 ILE A 226
MET A  95
VAL A  16
GLY A 228
 None
 1.30A 1e06B-4isbA:
undetectable		 1e06B-4isbA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ni2 GUANYLATE CYCLASE
SOLUBLE SUBUNIT
BETA-1

(Homo sapiens) 		PF00211
(Guanylate_cyc) 		4 ILE B 562
MET B 503
VAL B 469
GLY B 522
 None
None
EDO  B 702 ( 4.5A)
None
 1.40A 1e06B-4ni2B:
undetectable		 1e06B-4ni2B:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nzk UNCHARACTERIZED
PROTEIN

([Eubacterium]
siraeum) 		PF14286
(DHHW) 		4 ILE A 316
MET A 136
VAL A 216
GLY A 322
 None
 1.18A 1e06B-4nzkA:
undetectable		 1e06B-4nzkA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4phs PUTATIVE
GLYCOSYLTRANSFERASE
(GALT1)

(Streptococcus
parasanguinis) 		PF08759
(GT-D) 		4 ILE A  42
MET A  37
VAL A  27
GLY A  32
 None
 1.23A 1e06B-4phsA:
undetectable		 1e06B-4phsA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4prk 4-PHOSPHOERYTHRONATE
DEHYDROGENASE

(Lactobacillus
jensenii) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 ILE A 201
MET A 224
VAL A 239
GLY A 150
 None
 1.34A 1e06B-4prkA:
undetectable		 1e06B-4prkA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rul DNA TOPOISOMERASE 1

(Escherichia
coli) 		PF01131
(Topoisom_bac)
PF01396
(zf-C4_Topoisom)
PF01751
(Toprim)
PF08272
(Topo_Zn_Ribbon) 		4 ILE A 491
MET A 546
VAL A 175
GLY A 492
 None
 1.04A 1e06B-4rulA:
undetectable		 1e06B-4rulA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tsk KETOL-ACID
REDUCTOISOMERASE

(Alicyclobacillus
acidocaldarius) 		PF01450
(IlvC)
PF07991
(IlvN) 		4 ILE A  45
MET A  77
VAL A 136
GLY A  24
 None
None
None
NDP  A 405 ( 3.8A)
 1.01A 1e06B-4tskA:
undetectable		 1e06B-4tskA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uwm 3,6-DIKETOCAMPHANE
1,6 MONOOXYGENASE

(Pseudomonas
putida) 		PF00296
(Bac_luciferase) 		4 ILE A  38
MET A   3
VAL A 327
GLY A   6
 None
 1.44A 1e06B-4uwmA:
undetectable		 1e06B-4uwmA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uyp CELLULOSOMAL
SCAFFOLDIN ANCHORING
PROTEIN C

(Acetivibrio
cellulolyticus) 		PF00963
(Cohesin) 		4 ILE A  56
MET A  75
VAL A   4
GLY A  53
 None
 1.09A 1e06B-4uypA:
undetectable		 1e06B-4uypA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xvm DNA POLYMERASE NU

(Homo sapiens) 		PF00476
(DNA_pol_A) 		4 ILE A 345
MET A 310
VAL A 437
GLY A 346
 None
 1.21A 1e06B-4xvmA:
undetectable		 1e06B-4xvmA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y9d C
ALPHA-DEHYDROGENASE

(Sphingobium sp.
SYK-6) 		PF00106
(adh_short) 		4 ILE A  64
MET A 123
VAL A 184
GLY A 118
 NAI  A 401 (-3.9A)
None
None
None
 1.33A 1e06B-4y9dA:
undetectable		 1e06B-4y9dA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yji ARYL ACYLAMIDASE

(bacterium
CSBL00001) 		PF01425
(Amidase) 		4 ILE A 428
MET A 325
VAL A 381
GLY A 185
 None
None
None
TYL  A 502 (-3.6A)
 1.02A 1e06B-4yjiA:
undetectable		 1e06B-4yjiA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yuf CORB

(Corallococcus
coralloides) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 ILE A 262
MET A 331
VAL A 175
GLY A 317
 None
 1.31A 1e06B-4yufA:
undetectable		 1e06B-4yufA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z3y BENZOYL-COA
REDUCTASE, PUTATIVE

(Geobacter
metallireducens) 		PF01314
(AFOR_C)
PF02730
(AFOR_N) 		4 ILE A 189
MET A  94
VAL A 579
GLY A 187
 None
MTE  A 702 (-4.5A)
None
None
 1.02A 1e06B-4z3yA:
undetectable		 1e06B-4z3yA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zbt ACETOACETATE
DECARBOXYLASE

(Streptomyces
bingchenggensis) 		PF06314
(ADC) 		4 ILE A 165
MET A  61
VAL A 214
GLY A 245
 None
 0.78A 1e06B-4zbtA:
undetectable		 1e06B-4zbtA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a22 VESICULAR STOMATITIS
VIRUS L POLYMERASE

(Vesicular
stomatitis
virus) 		PF00946
(Mononeg_RNA_pol)
PF14314
(Methyltrans_Mon)
PF14318
(Mononeg_mRNAcap) 		4 ILE A 238
MET A 233
VAL A 275
GLY A 240
 None
 1.23A 1e06B-5a22A:
undetectable		 1e06B-5a22A:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b8i PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Coccidioides
immitis) 		PF00254
(FKBP_C) 		4 ILE C 124
MET C  84
VAL C  73
GLY C 123
 None
None
FK5  C 201 (-3.5A)
None
 0.96A 1e06B-5b8iC:
undetectable		 1e06B-5b8iC:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5chs RNA-DIRECTED RNA
POLYMERASE L

(Indiana
vesiculovirus) 		PF00946
(Mononeg_RNA_pol) 		4 ILE A 238
MET A 233
VAL A 275
GLY A 240
 None
 1.17A 1e06B-5chsA:
undetectable		 1e06B-5chsA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gs6 NS1 OF ZIKA VIRUS
FROM 2015 BRAZIL
STRAIN

(Zika virus) 		PF00948
(Flavi_NS1) 		4 ILE A 218
MET A  63
VAL A 162
GLY A 199
 None
 1.19A 1e06B-5gs6A:
undetectable		 1e06B-5gs6A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h5y NON-LEE ENCODED
EFFECTOR PROTEIN
NLEB

(Escherichia
coli) 		no annotation 4 ILE A  85
MET A 219
VAL A  59
GLY A  86
 None
 1.04A 1e06B-5h5yA:
undetectable		 1e06B-5h5yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hxg FLAGELLAR
TRANSCRIPTIONAL
REGULATOR FLHD

(Salmonella
enterica) 		PF05247
(FlhD) 		4 ILE B  28
MET B  45
VAL B  67
GLY B  50
 None
 1.26A 1e06B-5hxgB:
undetectable		 1e06B-5hxgB:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j6e FK506-BINDING
PROTEIN 1A

(Aspergillus
fumigatus) 		PF00254
(FKBP_C) 		4 ILE A 107
MET A  67
VAL A  56
GLY A 106
 None
 0.92A 1e06B-5j6eA:
undetectable		 1e06B-5j6eA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l3d LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1A

(Homo sapiens) 		PF01593
(Amino_oxidase)
PF04433
(SWIRM) 		4 ILE A 266
MET A 342
VAL A 317
GLY A 265
 None
None
FAD  A 901 ( 4.7A)
None
 1.33A 1e06B-5l3dA:
undetectable		 1e06B-5l3dA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lfd ALLANTOIN RACEMASE

(Pseudomonas
fluorescens) 		no annotation 4 ILE A  95
MET A 183
VAL A 139
GLY A 201
 None
 1.27A 1e06B-5lfdA:
undetectable		 1e06B-5lfdA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5loy DESIGNED ANBU
PROTEIN

(synthetic
construct) 		PF00227
(Proteasome) 		4 ILE A 113
MET A  33
VAL A 203
GLY A   5
 None
 1.44A 1e06B-5loyA:
undetectable		 1e06B-5loyA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5msy GLYCOSIDE HYDROLASE

(Bacteroides
thetaiotaomicron) 		PF12904
(Collagen_bind_2)
PF13204
(DUF4038) 		4 ILE A 184
MET A 237
VAL A  88
GLY A 185
 None
 1.40A 1e06B-5msyA:
undetectable		 1e06B-5msyA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nji PHTHIOCEROL/PHENOLPH
THIOCEROL SYNTHESIS
POLYKETIDE SYNTHASE
TYPE I PPSC

(Mycobacterium
tuberculosis) 		PF14765
(PS-DH) 		4 ILE A1175
MET A1122
VAL A1043
GLY A1173
 None
 1.24A 1e06B-5njiA:
undetectable		 1e06B-5njiA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5udb DNA REPLICATION
LICENSING FACTOR
MCM2
DNA REPLICATION
LICENSING FACTOR
MCM6

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF00493
(MCM)
PF14551
(MCM_N)
PF17207
(MCM_OB)
PF00493
(MCM)
PF14551
(MCM_N)
PF17207
(MCM_OB) 		4 ILE 6 563
MET 2 501
VAL 2 603
GLY 6 562
 None
 0.98A 1e06B-5udb6:
undetectable		 1e06B-5udb6:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vev PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE

(Neisseria
gonorrhoeae) 		PF01071
(GARS_A)
PF02843
(GARS_C)
PF02844
(GARS_N) 		4 ILE A 196
MET A 298
VAL A   5
GLY A 290
 None
 1.33A 1e06B-5vevA:
undetectable		 1e06B-5vevA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y50 PROTEIN
DETOXIFICATION 14

(Arabidopsis
thaliana) 		no annotation 4 ILE A 212
MET A  44
VAL A  81
GLY A 213
 None
 1.21A 1e06B-5y50A:
undetectable		 1e06B-5y50A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aqj KETOL-ACID
REDUCTOISOMERASE
(NADP(+))

(Staphylococcus
aureus) 		no annotation 4 ILE A  45
MET A  77
VAL A 136
GLY A  24
 None
None
None
NDP  A 407 ( 3.7A)
 1.00A 1e06B-6aqjA:
undetectable		 1e06B-6aqjA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bhc PSEUDOPODIUM-ENRICHE
D ATYPICAL KINASE 1

(Homo sapiens) 		no annotation 4 ILE A1597
MET A1602
VAL A1553
GLY A1596
 None
 1.14A 1e06B-6bhcA:
undetectable		 1e06B-6bhcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bi4 DTDP-GLUCOSE
4,6-DEHYDRATASE

(Bacillus
anthracis) 		no annotation 4 ILE A 282
MET A 287
VAL A 121
GLY A 242
 None
 1.03A 1e06B-6bi4A:
undetectable		 1e06B-6bi4A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cn1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Pseudomonas
putida) 		no annotation 4 ILE A  62
MET A  53
VAL A 111
GLY A  58
 None
 1.37A 1e06B-6cn1A:
undetectable		 1e06B-6cn1A:
undetectable