SIMILAR PATTERNS OF AMINO ACIDS FOR 1DZM_A_BZMA600

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1a3y ODORANT BINDING
PROTEIN

(Sus scrofa) 		PF00061
(Lipocalin) 		8 ILE A  21
MET A  39
VAL A  80
ASN A  86
ASN A 102
MET A 114
GLY A 116
LEU A 118
 None
 0.31A 1dzmA-1a3yA:
31.0		 1dzmA-1a3yA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d5t GUANINE NUCLEOTIDE
DISSOCIATION
INHIBITOR

(Bos taurus) 		PF00996
(GDI) 		4 VAL A 343
ASN A  73
GLY A  40
LEU A  14
 None
 0.86A 1dzmA-1d5tA:
0.0		 1dzmA-1d5tA:
17.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1e5p APHRODISIN

(Mesocricetus
auratus) 		PF00061
(Lipocalin) 		4 ILE A  15
ASN A  80
ASN A  96
MET A 108
 None
 0.25A 1dzmA-1e5pA:
24.9		 1dzmA-1e5pA:
33.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ex9 LACTONIZING LIPASE

(Pseudomonas
aeruginosa) 		PF00561
(Abhydrolase_1) 		4 ILE A 142
MET A  16
GLY A 139
LEU A  50
 None
OCP  A 382 (-4.1A)
None
None
 0.63A 1dzmA-1ex9A:
undetectable		 1dzmA-1ex9A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f07 COENZYME
F420-DEPENDENT
N5,N10-METHYLENETETR
AHYDROMETHANOPTERIN
REDUCTASE

(Methanothermobacter
thermautotrophicus) 		PF00296
(Bac_luciferase) 		4 ILE A 185
MET A 157
VAL A  62
GLY A 162
 None
None
MPO  A 331 (-3.9A)
None
 0.97A 1dzmA-1f07A:
0.0		 1dzmA-1f07A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gq2 MALIC ENZYME

(Columba livia) 		PF00390
(malic)
PF03949
(Malic_M) 		4 ILE A 442
ASN A 411
GLY A 441
LEU A 433
 None
 0.84A 1dzmA-1gq2A:
undetectable		 1dzmA-1gq2A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gv0 MALATE DEHYDROGENASE

(Chlorobaculum
tepidum) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 ILE A 113
MET A 235
GLY A 274
LEU A 270
 None
 1.00A 1dzmA-1gv0A:
0.1		 1dzmA-1gv0A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gxl CHROMOSOME
SEGREGATION SMC
PROTEIN

(Thermotoga
maritima) 		PF06470
(SMC_hinge) 		4 VAL A 664
ASN A 663
GLY A 644
LEU A 646
 None
 0.79A 1dzmA-1gxlA:
undetectable		 1dzmA-1gxlA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3j BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE

(Plasmodium
falciparum) 		PF00303
(Thymidylat_synt) 		4 ASN C 394
ASN C 392
MET C 444
GLY C 427
 None
 0.97A 1dzmA-1j3jC:
0.0		 1dzmA-1j3jC:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE

(Rattus
norvegicus) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 ILE A 251
ASN A 164
GLY A 247
LEU A 244
 None
None
None
CAA  A 400 (-4.1A)
 0.99A 1dzmA-1jqiA:
undetectable		 1dzmA-1jqiA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT

(Mycobacterium
tuberculosis) 		PF01043
(SecA_PP_bind)
PF07516
(SecA_SW)
PF07517
(SecA_DEAD) 		4 ILE A 393
MET A 371
GLY A  89
LEU A  93
 None
 0.96A 1dzmA-1nl3A:
undetectable		 1dzmA-1nl3A:
10.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1obp ODORANT-BINDING
PROTEIN

(Bos taurus) 		PF00061
(Lipocalin) 		4 ILE A  22
ASN A  87
ASN A 103
GLY A 117
 UNX  A 186 (-3.9A)
UNX  A 197 (-3.7A)
UNX  A 198 ( 2.8A)
UNX  A 181 (-2.9A)
 0.36A 1dzmA-1obpA:
18.3		 1dzmA-1obpA:
43.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rz6 CYTOCHROME C
PEROXIDASE

(Marinobacter
hydrocarbonoclasticus) 		PF00034
(Cytochrom_C)
PF03150
(CCP_MauG) 		4 VAL A 204
ASN A 205
ASN A  89
GLY A 107
 None
None
HEM  A 401 (-4.4A)
None
 0.68A 1dzmA-1rz6A:
undetectable		 1dzmA-1rz6A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica) 		PF13531
(SBP_bac_11) 		4 ILE A 254
VAL A  36
GLY A 251
LEU A 246
 None
 0.90A 1dzmA-1sbpA:
undetectable		 1dzmA-1sbpA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wh8 HOMEOBOX PROTEIN
CUX-2

(Homo sapiens) 		PF02376
(CUT) 		4 ILE A  32
VAL A  96
ASN A  95
LEU A  66
 None
 0.92A 1dzmA-1wh8A:
undetectable		 1dzmA-1wh8A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c9k PESTICIDAL CRYSTAL
PROTEIN CRY4AA

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		4 VAL A 426
ASN A 472
GLY A  68
LEU A 476
 None
 0.90A 1dzmA-2c9kA:
undetectable		 1dzmA-2c9kA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dfs MYOSIN-5A

(Gallus gallus) 		PF00063
(Myosin_head)
PF00612
(IQ) 		5 ILE A 226
VAL A 416
ASN A 420
ASN A 238
GLY A 434
 None
 1.33A 1dzmA-2dfsA:
undetectable		 1dzmA-2dfsA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dkh 3-HYDROXYBENZOATE
HYDROXYLASE

(Comamonas
testosteroni) 		PF01494
(FAD_binding_3)
PF07976
(Phe_hydrox_dim) 		4 ILE A 601
VAL A 559
GLY A 606
LEU A 623
 None
 0.93A 1dzmA-2dkhA:
undetectable		 1dzmA-2dkhA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e7z ACETYLENE HYDRATASE
AHY

(Pelobacter
acetylenicus) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		4 ILE A 142
ASN A 386
MET A 387
GLY A 143
 None
 0.85A 1dzmA-2e7zA:
undetectable		 1dzmA-2e7zA:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fhx SPM-1

(Pseudomonas
aeruginosa) 		PF00753
(Lactamase_B) 		4 ILE B 223
ASN B 200
GLY B 219
LEU B 217
 None
 0.89A 1dzmA-2fhxB:
undetectable		 1dzmA-2fhxB:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h0b NEUREXIN-1-ALPHA

(Bos taurus) 		PF02210
(Laminin_G_2) 		4 VAL A 437
ASN A 318
GLY A 443
LEU A 445
 None
 0.84A 1dzmA-2h0bA:
undetectable		 1dzmA-2h0bA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hlp MALATE DEHYDROGENASE

(Haloarcula
marismortui) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 ILE A 134
MET A 257
VAL A 142
LEU A 293
 None
 0.97A 1dzmA-2hlpA:
undetectable		 1dzmA-2hlpA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j16 TYROSINE-PROTEIN
PHOSPHATASE YIL113W

(Saccharomyces
cerevisiae) 		PF00782
(DSPc) 		4 ILE B  55
ASN B 178
GLY B 143
LEU B  70
 None
None
SO4  B1198 (-3.8A)
None
 0.90A 1dzmA-2j16B:
undetectable		 1dzmA-2j16B:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mfq FIBROBLAST GROWTH
FACTOR RECEPTOR
SUBSTRATE 2

(Homo sapiens) 		PF02174
(IRS) 		4 ILE A 104
VAL A  23
MET A 100
LEU A  62
 None
 0.84A 1dzmA-2mfqA:
undetectable		 1dzmA-2mfqA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nbh FUNGAL HYDROPHOBIN

(Schizophyllum
commune) 		PF01185
(Hydrophobin) 		4 ILE A  63
VAL A  94
ASN A 106
LEU A  50
 None
 0.99A 1dzmA-2nbhA:
undetectable		 1dzmA-2nbhA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pbg 6-PHOSPHO-BETA-D-GAL
ACTOSIDASE

(Lactococcus
lactis) 		PF00232
(Glyco_hydro_1) 		4 VAL A 331
ASN A 270
GLY A 272
LEU A 274
 None
 0.86A 1dzmA-2pbgA:
undetectable		 1dzmA-2pbgA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qko POSSIBLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN

(Rhodococcus
jostii) 		PF00440
(TetR_N) 		4 ILE A  61
VAL A  32
GLY A  58
LEU A 119
 None
 0.97A 1dzmA-2qkoA:
undetectable		 1dzmA-2qkoA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rh7 GREEN FLUORESCENT
PROTEIN

(Renilla
reniformis) 		PF01353
(GFP) 		4 ILE A  46
VAL A 107
MET A  29
GLY A  31
 None
 0.74A 1dzmA-2rh7A:
2.7		 1dzmA-2rh7A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vyc BIODEGRADATIVE
ARGININE
DECARBOXYLASE

(Escherichia
coli) 		PF01276
(OKR_DC_1)
PF03709
(OKR_DC_1_N)
PF03711
(OKR_DC_1_C) 		4 ILE A  47
VAL A  21
GLY A  44
LEU A  75
 None
 0.73A 1dzmA-2vycA:
undetectable		 1dzmA-2vycA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wia FERROUS IRON
TRANSPORT PROTEIN B

(Klebsiella
pneumoniae) 		PF02421
(FeoB_N) 		4 ILE A 252
ASN A  11
ASN A 101
LEU A 141
 None
 0.93A 1dzmA-2wiaA:
undetectable		 1dzmA-2wiaA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zvw PROLIFERATING CELL
NUCLEAR ANTIGEN 2

(Arabidopsis
thaliana) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 ILE A 121
ASN A  74
MET A 119
LEU A  37
 None
 0.98A 1dzmA-2zvwA:
undetectable		 1dzmA-2zvwA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ddr HASR PROTEIN

(Serratia
marcescens) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 ILE A 164
ASN A 176
ASN A 174
GLY A 223
 None
 0.99A 1dzmA-3ddrA:
undetectable		 1dzmA-3ddrA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e15 GLUCOSE-6-PHOSPHATE
1-DEHYDROGENASE

(Plasmodium
vivax) 		PF01182
(Glucosamine_iso) 		4 VAL A  67
ASN A  31
GLY A 285
LEU A 249
 None
 0.96A 1dzmA-3e15A:
undetectable		 1dzmA-3e15A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fbt CHORISMATE MUTASE
AND SHIKIMATE
5-DEHYDROGENASE
FUSION PROTEIN

(Clostridium
acetobutylicum) 		PF01488
(Shikimate_DH)
PF08501
(Shikimate_dh_N) 		4 ILE A 172
ASN A 196
GLY A 194
LEU A 185
 None
 0.79A 1dzmA-3fbtA:
undetectable		 1dzmA-3fbtA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ibj CGMP-DEPENDENT
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF00233
(PDEase_I)
PF01590
(GAF)
PF13185
(GAF_2) 		4 ILE A 279
ASN A 351
GLY A 280
LEU A 250
 None
 0.92A 1dzmA-3ibjA:
undetectable		 1dzmA-3ibjA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ibj CGMP-DEPENDENT
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF00233
(PDEase_I)
PF01590
(GAF)
PF13185
(GAF_2) 		4 ILE A 546
ASN A 511
ASN A 509
GLY A 545
 None
 0.93A 1dzmA-3ibjA:
undetectable		 1dzmA-3ibjA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j4u MAJOR CAPSID PROTEIN

(Bordetella
virus BPP1) 		no annotation 4 ILE A 282
VAL A 330
ASN A 170
LEU A 323
 None
 0.90A 1dzmA-3j4uA:
undetectable		 1dzmA-3j4uA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jab GAFB DOMAIN OF
PHOSPHODIESTERASE 2A

(Bos taurus) 		PF01590
(GAF) 		4 ILE B 546
ASN B 511
ASN B 509
GLY B 545
 None
 0.95A 1dzmA-3jabB:
undetectable		 1dzmA-3jabB:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k17 LIN0012 PROTEIN

(Listeria
innocua) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		4 ILE A  55
MET A 103
ASN A  85
LEU A  43
 None
 0.85A 1dzmA-3k17A:
undetectable		 1dzmA-3k17A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ksc LEGA CLASS

(Pisum sativum) 		PF00190
(Cupin_1) 		4 ILE A 342
VAL A 415
GLY A 363
LEU A 365
 None
 0.86A 1dzmA-3kscA:
undetectable		 1dzmA-3kscA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lmk METABOTROPIC
GLUTAMATE RECEPTOR 5

(Homo sapiens) 		PF01094
(ANF_receptor) 		4 ILE A  37
VAL A 191
GLY A 145
LEU A 437
 None
 0.95A 1dzmA-3lmkA:
undetectable		 1dzmA-3lmkA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nnh CUGBP ELAV-LIKE
FAMILY MEMBER 1

(Homo sapiens) 		PF00076
(RRM_1) 		4 ILE A  92
VAL A  42
MET A  94
GLY A  21
 None
None
None
G  E   4 ( 3.4A)
 0.90A 1dzmA-3nnhA:
undetectable		 1dzmA-3nnhA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3no3 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE

(Parabacteroides
distasonis) 		PF03009
(GDPD) 		4 ILE A  28
VAL A  72
ASN A  42
GLY A  57
 None
 0.84A 1dzmA-3no3A:
undetectable		 1dzmA-3no3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o47 ADP-RIBOSYLATION
FACTOR
GTPASE-ACTIVATING
PROTEIN 1,
ADP-RIBOSYLATION
FACTOR 1

(Homo sapiens) 		PF00025
(Arf)
PF01412
(ArfGap) 		4 ILE A 150
ASN A 190
MET A 148
LEU A 169
 None
 0.93A 1dzmA-3o47A:
1.6		 1dzmA-3o47A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p1w RABGDI PROTEIN

(Plasmodium
falciparum) 		PF00996
(GDI) 		4 VAL A 356
ASN A  72
GLY A  40
LEU A  14
 None
 0.89A 1dzmA-3p1wA:
1.8		 1dzmA-3p1wA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3poy NEUREXIN-1-ALPHA

(Bos taurus) 		PF00008
(EGF)
PF02210
(Laminin_G_2) 		4 VAL A 453
ASN A 334
GLY A 459
LEU A 461
 None
 0.77A 1dzmA-3poyA:
undetectable		 1dzmA-3poyA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qhp TYPE 1 CAPSULAR
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
J (CAPJ)

(Helicobacter
pylori) 		PF00534
(Glycos_transf_1) 		4 ILE A 247
ASN A 325
ASN A 216
LEU A 235
 None
 0.95A 1dzmA-3qhpA:
undetectable		 1dzmA-3qhpA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6q CD180 ANTIGEN

(Mus musculus) 		PF13855
(LRR_8) 		4 ILE A 238
ASN A 207
ASN A 228
LEU A 188
 None
 1.00A 1dzmA-3t6qA:
undetectable		 1dzmA-3t6qA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tl2 MALATE DEHYDROGENASE

(Bacillus
anthracis) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 ILE A 119
MET A 241
GLY A 280
LEU A 276
 None
 0.96A 1dzmA-3tl2A:
undetectable		 1dzmA-3tl2A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tl2 MALATE DEHYDROGENASE

(Bacillus
anthracis) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 ILE A 119
MET A 241
VAL A 127
LEU A 276
 None
None
SCN  A 314 (-4.8A)
None
 0.89A 1dzmA-3tl2A:
undetectable		 1dzmA-3tl2A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ujh GLUCOSE-6-PHOSPHATE
ISOMERASE

(Toxoplasma
gondii) 		PF00342
(PGI) 		5 VAL A  95
ASN A  88
ASN A 508
MET A 371
GLY A 506
 None
 1.40A 1dzmA-3ujhA:
undetectable		 1dzmA-3ujhA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dpk MALONYL-COA/SUCCINYL
-COA REDUCTASE

(Sulfurisphaera
tokodaii) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 ILE A  21
MET A  26
ASN A 335
GLY A  20
 None
 0.94A 1dzmA-4dpkA:
undetectable		 1dzmA-4dpkA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dry 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE

(Sinorhizobium
meliloti) 		PF00106
(adh_short) 		4 ILE A 186
MET A 134
ASN A  94
GLY A 143
 None
 0.93A 1dzmA-4dryA:
undetectable		 1dzmA-4dryA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eba MRNA
3'-END-PROCESSING
PROTEIN RNA14

(Kluyveromyces
lactis) 		PF05843
(Suf) 		4 VAL A 224
ASN A 225
GLY A 234
LEU A 236
 None
 0.94A 1dzmA-4ebaA:
undetectable		 1dzmA-4ebaA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fk7 PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX

(Bacillus cereus) 		PF03496
(ADPrib_exo_Tox) 		4 ILE A 381
ASN A 288
ASN A 384
GLY A 437
 None
 0.80A 1dzmA-4fk7A:
undetectable		 1dzmA-4fk7A:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gwn MEPRIN A SUBUNIT
BETA

(Homo sapiens) 		PF00629
(MAM)
PF01400
(Astacin) 		4 ILE A  64
ASN A 130
GLY A 159
LEU A 252
 None
 0.85A 1dzmA-4gwnA:
undetectable		 1dzmA-4gwnA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iuy SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE

(Acinetobacter
baumannii) 		PF00106
(adh_short) 		4 ILE A 242
VAL A  89
ASN A 183
GLY A 241
 None
 0.99A 1dzmA-4iuyA:
undetectable		 1dzmA-4iuyA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jbe GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE

(Saccharomonospora
viridis) 		PF00171
(Aldedh) 		4 ILE A 205
ASN A 144
GLY A 122
LEU A 148
 ILE  A 205 ( 0.7A)
ASN  A 144 ( 0.6A)
GLY  A 122 ( 0.0A)
LEU  A 148 ( 0.5A)
 0.98A 1dzmA-4jbeA:
undetectable		 1dzmA-4jbeA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mpt PUTATIVE
LEU/ILE/VAL-BINDING
PROTEIN

(Bordetella
pertussis) 		PF13458
(Peripla_BP_6) 		4 ILE A 299
VAL A 109
GLY A 236
LEU A 211
 None
 0.92A 1dzmA-4mptA:
undetectable		 1dzmA-4mptA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mt1 DRUG EFFLUX PROTEIN

(Neisseria
gonorrhoeae) 		PF00873
(ACR_tran) 		4 ILE A 951
VAL A 452
GLY A 442
LEU A 888
 None
 1.00A 1dzmA-4mt1A:
undetectable		 1dzmA-4mt1A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nt4 GILGAMESH, ISOFORM I

(Drosophila
melanogaster) 		PF00069
(Pkinase) 		4 ILE A  71
MET A  38
ASN A  62
GLY A  60
 None
 0.92A 1dzmA-4nt4A:
undetectable		 1dzmA-4nt4A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pm3 AM32

(Enterococcus
faecalis) 		no annotation 4 ILE A  51
MET A  15
ASN A   5
ASN A  58
 None
 1.00A 1dzmA-4pm3A:
undetectable		 1dzmA-4pm3A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pmu ENDO-1,4-BETA-XYLANA
SE A

(Xanthomonas
citri) 		PF00331
(Glyco_hydro_10) 		4 ILE A 211
VAL A 169
MET A 214
GLY A 210
 None
 0.81A 1dzmA-4pmuA:
undetectable		 1dzmA-4pmuA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q00 FERROUS IRON
TRANSPORT PROTEIN B

(Escherichia
coli) 		PF02421
(FeoB_N) 		4 ILE A 252
ASN A  11
ASN A 101
LEU A 141
 None
 0.89A 1dzmA-4q00A:
undetectable		 1dzmA-4q00A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qj4 1-PHOSPHATIDYLINOSIT
OL 4,5-BISPHOSPHATE
PHOSPHODIESTERASE
BETA-3

(Homo sapiens) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		4 VAL B 365
ASN B 414
ASN B 467
LEU B 437
 None
 0.54A 1dzmA-4qj4B:
undetectable		 1dzmA-4qj4B:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r04 TOXIN A

(Clostridioides
difficile) 		PF11713
(Peptidase_C80)
PF12918
(TcdB_N)
PF12919
(TcdA_TcdB)
PF12920
(TcdA_TcdB_pore) 		4 VAL A1530
ASN A1558
GLY A1612
LEU A1610
 None
 0.87A 1dzmA-4r04A:
1.4		 1dzmA-4r04A:
7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r9n LMO0547 PROTEIN

(Listeria
monocytogenes) 		PF04198
(Sugar-bind) 		4 ILE A 120
VAL A 261
ASN A 242
GLY A 208
 None
 0.93A 1dzmA-4r9nA:
undetectable		 1dzmA-4r9nA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rul DNA TOPOISOMERASE 1

(Escherichia
coli) 		PF01131
(Topoisom_bac)
PF01396
(zf-C4_Topoisom)
PF01751
(Toprim)
PF08272
(Topo_Zn_Ribbon) 		4 ILE A 491
MET A 546
VAL A 175
GLY A 492
 None
 1.00A 1dzmA-4rulA:
undetectable		 1dzmA-4rulA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xnq INFLUENZA H5 HA HEAD
DOMAIN VIETNAM RDT
MUTATIONS

(Influenza A
virus) 		no annotation 4 ILE D  87
VAL D 151
ASN D 150
LEU D 108
 None
 0.82A 1dzmA-4xnqD:
undetectable		 1dzmA-4xnqD:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y7p ALKALINE D-PEPTIDASE

(Bacillus cereus) 		PF00144
(Beta-lactamase) 		4 ILE A 129
VAL A 284
GLY A 175
LEU A 179
 None
 0.97A 1dzmA-4y7pA:
1.3		 1dzmA-4y7pA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ywo MERCURIC REDUCTASE

(Metallosphaera
sedula) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 VAL A  40
ASN A  41
GLY A  31
LEU A  29
 None
None
FAD  A 501 (-3.5A)
None
 0.88A 1dzmA-4ywoA:
undetectable		 1dzmA-4ywoA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zbt ACETOACETATE
DECARBOXYLASE

(Streptomyces
bingchenggensis) 		PF06314
(ADC) 		4 ILE A 165
MET A  61
VAL A 214
GLY A 245
 None
 0.80A 1dzmA-4zbtA:
undetectable		 1dzmA-4zbtA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5axh DEXTRANASE

(Thermoanaerobacter
pseudethanolicus) 		PF13199
(Glyco_hydro_66) 		4 MET A 468
ASN A 410
GLY A 446
LEU A 442
 None
None
GOL  A 707 (-3.5A)
None
 0.87A 1dzmA-5axhA:
undetectable		 1dzmA-5axhA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b8i PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Coccidioides
immitis) 		PF00254
(FKBP_C) 		4 ILE C 124
MET C  84
VAL C  73
GLY C 123
 None
None
FK5  C 201 (-3.5A)
None
 0.99A 1dzmA-5b8iC:
undetectable		 1dzmA-5b8iC:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e7p CELL DIVISION
CONTROL PROTEIN
CDC48

(Mycolicibacterium
smegmatis) 		PF00004
(AAA)
PF02359
(CDC48_N) 		4 ILE A 670
VAL A 726
GLY A 667
LEU A 678
 None
 0.94A 1dzmA-5e7pA:
undetectable		 1dzmA-5e7pA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ffo INTEGRIN BETA-6

(Homo sapiens) 		PF00362
(Integrin_beta) 		4 ILE B 196
MET B 122
ASN B 212
LEU B 124
 None
 0.99A 1dzmA-5ffoB:
undetectable		 1dzmA-5ffoB:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gl9 BETA-LACTAMASE

(Burkholderia
thailandensis) 		PF13354
(Beta-lactamase2) 		4 ILE A 247
ASN A 214
GLY A 248
LEU A 194
 None
 0.92A 1dzmA-5gl9A:
2.9		 1dzmA-5gl9A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gqr LEUCINE-RICH REPEAT
RECEPTOR-LIKE
PROTEIN KINASE TDR

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8) 		4 MET B 374
VAL B 337
GLY B 366
LEU B 389
 None
 0.98A 1dzmA-5gqrB:
undetectable		 1dzmA-5gqrB:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gsl 778AA LONG
HYPOTHETICAL
BETA-GALACTOSIDASE

(Pyrococcus
horikoshii) 		PF02449
(Glyco_hydro_42) 		4 ILE A 664
MET A 484
VAL A 680
LEU A 324
 None
 0.94A 1dzmA-5gslA:
undetectable		 1dzmA-5gslA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h3o CYCLIC
NUCLEOTIDE-GATED
CATION CHANNEL

(Caenorhabditis
elegans) 		PF00027
(cNMP_binding)
PF00520
(Ion_trans)
PF16526
(CLZ) 		4 ILE A 616
VAL A 491
GLY A 613
LEU A 564
 PCG  A 801 ( 4.9A)
None
None
None
 0.89A 1dzmA-5h3oA:
undetectable		 1dzmA-5h3oA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hb1 NUCLEOPORIN NUP170

(Chaetomium
thermophilum) 		PF03177
(Nucleoporin_C) 		4 ILE A 771
VAL A 782
GLY A 770
LEU A 805
 None
 0.96A 1dzmA-5hb1A:
undetectable		 1dzmA-5hb1A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE

(Corynebacterium
glutamicum) 		PF01474
(DAHP_synth_2) 		4 ILE A 420
VAL A  84
GLY A  94
LEU A 116
 None
 0.86A 1dzmA-5hucA:
undetectable		 1dzmA-5hucA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i68 ALCOHOL OXIDASE 1

(Komagataella
pastoris) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 ILE A  21
VAL A 276
GLY A  18
LEU A  36
 None
 0.99A 1dzmA-5i68A:
undetectable		 1dzmA-5i68A:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6c URIC ACID-XANTHINE
PERMEASE

(Aspergillus
nidulans) 		PF00860
(Xan_ur_permease) 		5 ILE A 131
VAL A 367
ASN A 410
ASN A 409
GLY A 424
 None
 1.27A 1dzmA-5i6cA:
undetectable		 1dzmA-5i6cA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jta NEUTRAL TREHALASE

(Saccharomyces
cerevisiae) 		no annotation 4 ILE A 344
VAL A 368
GLY A 308
LEU A 306
 None
 0.67A 1dzmA-5jtaA:
undetectable		 1dzmA-5jtaA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lnx ACYL-COA
DEHYDROGENASE

(Bacillus
subtilis) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 ILE A 244
ASN A 157
GLY A 240
LEU A 237
 None
None
None
GOL  A 401 ( 4.5A)
 0.94A 1dzmA-5lnxA:
undetectable		 1dzmA-5lnxA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m4a NEUTRAL TREHALASE

(Saccharomyces
cerevisiae) 		no annotation 4 ILE A 344
VAL A 368
GLY A 308
LEU A 306
 None
 0.59A 1dzmA-5m4aA:
undetectable		 1dzmA-5m4aA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mal LIPASE

(Streptomyces
rimosus) 		PF13472
(Lipase_GDSL_2) 		4 ILE A 112
VAL A 188
ASN A 171
LEU A 120
 None
 0.96A 1dzmA-5malA:
undetectable		 1dzmA-5malA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mh5 D-2-HYDROXYACID
DEHYDROGENASE

(Haloferax
mediterranei) 		no annotation 4 ILE A 244
VAL A 224
ASN A 223
GLY A 246
 None
NAP  A 414 (-4.5A)
None
None
 0.99A 1dzmA-5mh5A:
undetectable		 1dzmA-5mh5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B

(Acinetobacter
calcoaceticus) 		no annotation 4 ILE A  69
ASN A 112
GLY A  98
LEU A  80
 None
 0.87A 1dzmA-5minA:
undetectable		 1dzmA-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5msn DCC1 PROTEIN

(Saccharomyces
cerevisiae) 		PF09724
(Dcc1) 		4 VAL A 208
ASN A 236
GLY A 169
LEU A 180
 None
 0.89A 1dzmA-5msnA:
undetectable		 1dzmA-5msnA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n0o PEPTIDE
N-METHYLTRANSFERASE

(Omphalotus
olearius) 		no annotation 4 ILE A 114
MET A  83
ASN A 106
LEU A  12
 None
 0.70A 1dzmA-5n0oA:
undetectable		 1dzmA-5n0oA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oki SISTER CHROMATID
COHESION PROTEIN
DCC1

(Saccharomyces
cerevisiae) 		no annotation 4 VAL C 208
ASN C 236
GLY C 169
LEU C 180
 None
 0.91A 1dzmA-5okiC:
undetectable		 1dzmA-5okiC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ol2 ACYL-COA
DEHYDROGENASE

(Clostridioides
difficile) 		no annotation 4 ILE C 245
ASN C 158
GLY C 241
LEU C 238
 None
None
None
COS  C 402 (-4.4A)
 0.87A 1dzmA-5ol2C:
undetectable		 1dzmA-5ol2C:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xog DNA-DIRECTED RNA
POLYMERASE SUBUNIT

(Komagataella
phaffii) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 MET A 606
VAL A 532
GLY A 629
LEU A 589
 None
 0.86A 1dzmA-5xogA:
undetectable		 1dzmA-5xogA:
7.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xsx CHITINASE

(Thermococcus
chitonophagus) 		no annotation 4 ILE A 434
ASN A 523
ASN A 521
MET A 472
 None
 0.61A 1dzmA-5xsxA:
undetectable		 1dzmA-5xsxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yq3 AT3G55470

(Arabidopsis
thaliana) 		no annotation 4 ILE A  31
ASN A  50
ASN A  54
GLY A 144
 None
 0.97A 1dzmA-5yq3A:
undetectable		 1dzmA-5yq3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b7t GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN

(Aequorea
victoria) 		no annotation 4 ASN A 200
ASN A 174
GLY A -11
LEU A   7
 None
 0.94A 1dzmA-6b7tA:
2.0		 1dzmA-6b7tA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ezn DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT WBP1

(Saccharomyces
cerevisiae) 		no annotation 4 ILE G 232
ASN G 242
ASN G 246
LEU G 254
 None
 0.78A 1dzmA-6eznG:
undetectable		 1dzmA-6eznG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6frl TRYPTOPHAN
HALOGENASE
SUPERFAMILY

(Brevundimonas
sp. BAL3) 		no annotation 4 ILE A   9
VAL A 228
ASN A 334
LEU A 363
 None
 0.98A 1dzmA-6frlA:
1.0		 1dzmA-6frlA:
undetectable