SIMILAR PATTERNS OF AMINO ACIDS FOR 1DTL_A_BEPA204_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1avs TROPONIN C

(Gallus gallus) 		PF13833
(EF-hand_8) 		7 PHE A  29
ILE A  37
LEU A  42
MET A  46
LEU A  49
VAL A  65
MET A  81
 None
 0.76A 1dtlA-1avsA:
14.6		 1dtlA-1avsA:
54.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bfo CAMPATH-1G ANTIBODY

(Rattus rattus) 		PF07654
(C1-set)
PF07686
(V-set) 		6 PHE A  62
ILE A  58
LEU A  47
LEU A  21
LEU A 106
LEU A 104
 None
 1.45A 1dtlA-1bfoA:
undetectable		 1dtlA-1bfoA:
19.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ggz CALMODULIN-RELATED
PROTEIN NB-1

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 PHE A  19
ILE A  27
LEU A  32
MET A  36
LEU A  39
MET A  51
 None
 0.60A 1dtlA-1ggzA:
13.6		 1dtlA-1ggzA:
43.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1oqp CALTRACTIN

(Chlamydomonas
reinhardtii) 		PF13499
(EF-hand_7) 		5 PHE A 110
ILE A 118
LEU A 123
LEU A 130
MET A 142
 None
 0.64A 1dtlA-1oqpA:
11.7		 1dtlA-1oqpA:
33.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wf9 NPL4 FAMILY PROTEIN

(Arabidopsis
thaliana) 		PF11543
(UN_NPL4) 		5 LEU A  33
MET A  71
VAL A  21
LEU A  57
LEU A  56
 None
 1.05A 1dtlA-1wf9A:
undetectable		 1dtlA-1wf9A:
19.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1wrk TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES

(Homo sapiens) 		PF13833
(EF-hand_8) 		5 ILE A  36
LEU A  41
MET A  45
LEU A  48
MET A  60
 None
None
TFP  A 202 (-3.6A)
TFP  A 202 (-4.1A)
TFP  A 202 ( 4.0A)
 0.55A 1dtlA-1wrkA:
14.4		 1dtlA-1wrkA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1wrk TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES

(Homo sapiens) 		PF13833
(EF-hand_8) 		5 LEU A  41
MET A  45
LEU A  48
MET A  60
VAL A  64
 None
TFP  A 202 (-3.6A)
TFP  A 202 (-4.1A)
TFP  A 202 ( 4.0A)
None
 0.48A 1dtlA-1wrkA:
14.4		 1dtlA-1wrkA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1zot CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		7 PHE B  92
ILE B 100
LEU B 105
MET B 109
LEU B 112
MET B 124
MET B 144
 None
 0.72A 1dtlA-1zotB:
11.4		 1dtlA-1zotB:
30.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2aao CALCIUM-DEPENDENT
PROTEIN KINASE,
ISOFORM AK1

(Arabidopsis
thaliana) 		PF13499
(EF-hand_7) 		5 PHE A 108
ILE A 116
LEU A 121
VAL A 142
MET A 158
 None
 0.80A 1dtlA-2aaoA:
6.2		 1dtlA-2aaoA:
36.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cxn GLUCOSE-6-PHOSPHATE
ISOMERASE

(Mus musculus) 		PF00342
(PGI) 		5 PHE A 264
LEU A 246
LEU A 286
VAL A 253
LEU A 205
 None
 1.02A 1dtlA-2cxnA:
undetectable		 1dtlA-2cxnA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d58 ALLOGRAFT
INFLAMMATORY FACTOR
1

(Homo sapiens) 		no annotation 5 PHE A  57
ILE A  65
LEU A  70
LEU A  77
VAL A  93
 None
 0.95A 1dtlA-2d58A:
9.3		 1dtlA-2d58A:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dpm PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1)

(Streptococcus
pneumoniae) 		PF02086
(MethyltransfD12) 		5 ILE A 173
LEU A  81
VAL A  44
LEU A 125
LEU A 122
 None
 0.94A 1dtlA-2dpmA:
undetectable		 1dtlA-2dpmA:
18.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f2p CALMODULIN FUSED
WITH
CALMODULIN-BINDING
DOMAIN OF
CALCINEURIN

(Bos taurus) 		PF13499
(EF-hand_7) 		5 ILE A 100
LEU A 105
MET A 109
LEU A 112
MET A 124
 None
 0.90A 1dtlA-2f2pA:
11.4		 1dtlA-2f2pA:
44.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f2p CALMODULIN FUSED
WITH
CALMODULIN-BINDING
DOMAIN OF
CALCINEURIN

(Bos taurus) 		PF13499
(EF-hand_7) 		7 PHE A  19
ILE A  27
LEU A  32
MET A  36
LEU A  39
MET A  51
VAL A  55
 None
 0.63A 1dtlA-2f2pA:
11.4		 1dtlA-2f2pA:
44.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f2p CALMODULIN FUSED
WITH
CALMODULIN-BINDING
DOMAIN OF
CALCINEURIN

(Bos taurus) 		PF13499
(EF-hand_7) 		5 PHE A  19
ILE A  27
LEU A  32
VAL A  55
MET A  71
 None
 0.92A 1dtlA-2f2pA:
11.4		 1dtlA-2f2pA:
44.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f2p CALMODULIN FUSED
WITH
CALMODULIN-BINDING
DOMAIN OF
CALCINEURIN

(Bos taurus) 		PF13499
(EF-hand_7) 		5 PHE A  92
ILE A 100
LEU A 105
LEU A 112
MET A 144
 None
 0.87A 1dtlA-2f2pA:
11.4		 1dtlA-2f2pA:
44.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ggm CENTRIN-2

(Homo sapiens) 		PF13499
(EF-hand_7) 		5 LEU A  53
MET A  57
LEU A  60
MET A  72
GLU A  99
 None
 1.05A 1dtlA-2ggmA:
11.6		 1dtlA-2ggmA:
37.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ggm CENTRIN-2

(Homo sapiens) 		PF13499
(EF-hand_7) 		5 PHE A 113
ILE A 121
LEU A 126
LEU A 133
MET A 145
 None
 0.51A 1dtlA-2ggmA:
11.6		 1dtlA-2ggmA:
37.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jjz IONIZED
CALCIUM-BINDING
ADAPTER MOLECULE 2

(Homo sapiens) 		no annotation 8 PHE B  59
ILE B  67
LEU B  72
MET B  76
LEU B  79
MET B  91
VAL B  95
MET B 111
 None
 0.75A 1dtlA-2jjzB:
8.9		 1dtlA-2jjzB:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k7d CALCIUM-BINDING
PROTEIN 1

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 PHE A 111
ILE A 119
LEU A 124
MET A 128
LEU A 131
VAL A 148
 None
 1.19A 1dtlA-2k7dA:
8.7		 1dtlA-2k7dA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kn2 CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		5 PHE A  18
ILE A  26
LEU A  31
LEU A  38
MET A  50
 None
 0.90A 1dtlA-2kn2A:
10.9		 1dtlA-2kn2A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kn2 CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		5 PHE A  18
ILE A  26
LEU A  31
MET A  35
LEU A  38
 None
 0.51A 1dtlA-2kn2A:
10.9		 1dtlA-2kn2A:
24.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l1w CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		6 PHE A  92
ILE A 100
LEU A 105
MET A 109
LEU A 112
MET A 124
 None
 0.88A 1dtlA-2l1wA:
10.5		 1dtlA-2l1wA:
43.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l1w CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		5 PHE A  92
ILE A 100
LEU A 105
MET A 109
MET A 144
 None
 0.77A 1dtlA-2l1wA:
10.5		 1dtlA-2l1wA:
43.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2lhh CALMODULIN

(Saccharomyces
cerevisiae) 		PF00036
(EF-hand_1)
PF13499
(EF-hand_7) 		5 PHE A  19
ILE A  27
LEU A  32
MET A  36
LEU A  39
 None
CA  A 201 ( 4.4A)
None
None
None
 0.98A 1dtlA-2lhhA:
7.8		 1dtlA-2lhhA:
36.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2lhi CALMODULIN,
SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2B
CATALYTIC SUBUNIT A1

(Saccharomyces
cerevisiae;
synthetic
construct) 		PF13499
(EF-hand_7) 		5 PHE A  19
ILE A  27
LEU A  32
MET A  36
LEU A  39
 None
 0.85A 1dtlA-2lhiA:
12.5		 1dtlA-2lhiA:
34.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2lmv CALMODULIN-RELATED
PROTEIN 97A

(Drosophila
melanogaster) 		PF13499
(EF-hand_7) 		5 ILE A 100
LEU A 105
MET A 109
LEU A 112
MET A 124
 None
 0.89A 1dtlA-2lmvA:
8.5		 1dtlA-2lmvA:
38.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lv7 CALCIUM-BINDING
PROTEIN 7

(Homo sapiens) 		PF13499
(EF-hand_7) 		5 PHE A  42
ILE A  53
LEU A  58
MET A  62
LEU A  65
 None
 1.03A 1dtlA-2lv7A:
7.7		 1dtlA-2lv7A:
21.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2n6a HUMAN
CALMODULIN/CONNEXIN-
36 PEPTIDE HYBRID

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 PHE A  19
ILE A  27
LEU A  32
LEU A  39
VAL A  55
MET A  71
 None
 1.09A 1dtlA-2n6aA:
12.5		 1dtlA-2n6aA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2n6a HUMAN
CALMODULIN/CONNEXIN-
36 PEPTIDE HYBRID

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 PHE A  19
ILE A  27
LEU A  32
MET A  36
LEU A  39
MET A  51
 None
 1.11A 1dtlA-2n6aA:
12.5		 1dtlA-2n6aA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2n6a HUMAN
CALMODULIN/CONNEXIN-
36 PEPTIDE HYBRID

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 PHE A  19
ILE A  27
LEU A  32
MET A  36
LEU A  39
VAL A  55
 None
 1.07A 1dtlA-2n6aA:
12.5		 1dtlA-2n6aA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2n6a HUMAN
CALMODULIN/CONNEXIN-
36 PEPTIDE HYBRID

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 PHE A  92
ILE A 100
LEU A 105
MET A 109
LEU A 112
MET A 124
 None
 0.79A 1dtlA-2n6aA:
12.5		 1dtlA-2n6aA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2n7l TROPONIN C/TROPONIN
I CHIMERA

(Homo sapiens) 		PF13833
(EF-hand_8) 		5 ILE C  36
LEU C  41
MET C  45
LEU C  48
VAL C  64
 4J4  C  84 ( 4.3A)
4J4  C  84 ( 4.1A)
None
None
4J4  C  84 ( 3.7A)
 1.00A 1dtlA-2n7lC:
9.9		 1dtlA-2n7lC:
56.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2obh CENTRIN-2

(Homo sapiens) 		PF13499
(EF-hand_7) 		5 PHE A 113
ILE A 121
LEU A 126
LEU A 133
MET A 145
 None
 0.52A 1dtlA-2obhA:
11.5		 1dtlA-2obhA:
40.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ro9 CALMODULIN-2

(Glycine max) 		PF13499
(EF-hand_7) 		5 PHE A  92
ILE A 100
LEU A 105
LEU A 112
MET A 124
 None
 1.02A 1dtlA-2ro9A:
11.1		 1dtlA-2ro9A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ro9 CALMODULIN-2

(Glycine max) 		PF13499
(EF-hand_7) 		5 PHE A  92
ILE A 100
LEU A 105
MET A 109
MET A 124
 None
 0.94A 1dtlA-2ro9A:
11.1		 1dtlA-2ro9A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rob CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		5 ILE A 100
LEU A 105
MET A 109
LEU A 112
MET A 124
 None
 0.85A 1dtlA-2robA:
10.4		 1dtlA-2robA:
23.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2w49 TROPONIN C, SKELETAL
MUSCLE

(Gallus gallus) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		5 PHE 0  28
ILE 0  36
LEU 0  41
MET 0  45
LEU 0  48
 None
 0.78A 1dtlA-2w490:
13.1		 1dtlA-2w490:
67.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2w49 TROPONIN C, SKELETAL
MUSCLE

(Gallus gallus) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		5 PHE 0  28
ILE 0  36
MET 0  45
LEU 0  48
VAL 0  64
 None
 0.98A 1dtlA-2w490:
13.1		 1dtlA-2w490:
67.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3b32 CALMODULIN

(Rattus
norvegicus) 		PF13499
(EF-hand_7) 		5 ILE A  27
LEU A  32
MET A  51
VAL A  55
MET A  71
 None
 0.97A 1dtlA-3b32A:
11.6		 1dtlA-3b32A:
59.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3b32 CALMODULIN

(Rattus
norvegicus) 		PF13499
(EF-hand_7) 		7 PHE A  19
ILE A  27
LEU A  32
MET A  36
LEU A  39
MET A  51
VAL A  55
 None
 0.63A 1dtlA-3b32A:
11.6		 1dtlA-3b32A:
59.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA

(Aequorea
victoria;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		8 PHE A 322
ILE A 330
LEU A 335
MET A 339
LEU A 342
MET A 354
VAL A 358
MET A 374
 None
 0.66A 1dtlA-3evrA:
14.6		 1dtlA-3evrA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA

(Aequorea
victoria;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		6 PHE A 395
ILE A 403
LEU A 408
MET A 412
LEU A 415
MET A 427
 None
 0.57A 1dtlA-3evrA:
14.6		 1dtlA-3evrA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fwb CELL DIVISION
CONTROL PROTEIN 31

(Saccharomyces
cerevisiae) 		PF13499
(EF-hand_7) 		5 PHE A 105
ILE A 113
LEU A 118
LEU A 125
MET A 137
 None
 0.34A 1dtlA-3fwbA:
11.5		 1dtlA-3fwbA:
30.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gbz KINASE, CMGC CDK

(Giardia
intestinalis) 		PF00069
(Pkinase) 		5 ILE A 121
LEU A 120
MET A 281
LEU A 266
LEU A 211
 None
 0.99A 1dtlA-3gbzA:
undetectable		 1dtlA-3gbzA:
17.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ifk CALMODULIN

(Rattus
norvegicus) 		PF13499
(EF-hand_7) 		8 PHE A  19
ILE A  27
LEU A  32
MET A  36
LEU A  39
MET A  51
VAL A  55
MET A  71
 None
 0.48A 1dtlA-3ifkA:
11.8		 1dtlA-3ifkA:
57.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3igo CALMODULIN-DOMAIN
PROTEIN KINASE 1

(Cryptosporidium
parvum) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		5 ILE A 186
LEU A 199
LEU A 160
LEU A 268
LEU A 267
 None
 1.05A 1dtlA-3igoA:
7.3		 1dtlA-3igoA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iq1 DPS FAMILY PROTEIN

(Vibrio cholerae) 		PF00210
(Ferritin) 		5 PHE A  30
ILE A  91
LEU A 147
LEU A 155
LEU A 151
 None
 1.02A 1dtlA-3iq1A:
undetectable		 1dtlA-3iq1A:
23.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3k21 CALCIUM-DEPENDENT
PROTEIN KINASE 3

(Plasmodium
falciparum) 		PF13499
(EF-hand_7) 		6 PHE A 131
ILE A 139
LEU A 144
MET A 168
VAL A 172
MET A 188
 None
 0.69A 1dtlA-3k21A:
9.5		 1dtlA-3k21A:
30.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3kf9 CALTRACTIN

(Scherffelia
dubia) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		7 PHE A  36
ILE A  44
LEU A  49
MET A  53
LEU A  56
MET A  68
MET A  88
 None
 0.69A 1dtlA-3kf9A:
15.3		 1dtlA-3kf9A:
40.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3kf9 CALTRACTIN

(Scherffelia
dubia) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		6 PHE A 109
ILE A 117
LEU A 122
LEU A 129
MET A 141
MET A 162
 None
 1.06A 1dtlA-3kf9A:
15.3		 1dtlA-3kf9A:
40.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kl8 CALCIUM/CALMODULIN
DEPENDENT PROTEIN
KINASE II

(Caenorhabditis
elegans) 		PF00069
(Pkinase) 		5 ILE A 123
LEU A 136
LEU A  97
LEU A 206
LEU A 205
 None
 1.02A 1dtlA-3kl8A:
undetectable		 1dtlA-3kl8A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l19 CALCIUM/CALMODULIN
DEPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum) 		PF13499
(EF-hand_7) 		5 PHE A 458
ILE A 466
LEU A 471
MET A 488
MET A 508
 None
 0.79A 1dtlA-3l19A:
7.5		 1dtlA-3l19A:
27.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o4y CALCIUM-DEPENDENT
PROTEIN KINASE 3

(Plasmodium
vivax) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		5 PHE A 134
ILE A 142
LEU A 147
VAL A 175
MET A 191
 None
 0.69A 1dtlA-3o4yA:
8.1		 1dtlA-3o4yA:
28.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3qrx CENTRIN

(Chlamydomonas
reinhardtii) 		PF13499
(EF-hand_7) 		5 PHE A  37
ILE A  45
LEU A  50
MET A  54
MET A  69
 None
 0.76A 1dtlA-3qrxA:
12.2		 1dtlA-3qrxA:
41.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3qrx CENTRIN

(Chlamydomonas
reinhardtii) 		PF13499
(EF-hand_7) 		5 PHE A 110
ILE A 118
LEU A 123
LEU A 130
MET A 142
 None
 0.87A 1dtlA-3qrxA:
12.2		 1dtlA-3qrxA:
41.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sl5 CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D

(Homo sapiens) 		PF00233
(PDEase_I) 		5 LEU A  96
VAL A 106
GLU A 150
LEU A 149
LEU A 146
 LEU  A  96 ( 0.5A)
VAL  A 106 ( 0.6A)
GLU  A 150 ( 0.5A)
LEU  A 149 ( 0.6A)
LEU  A 146 ( 0.5A)
 1.04A 1dtlA-3sl5A:
undetectable		 1dtlA-3sl5A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0k RCAMP

(Entacmaea
quadricolor) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		7 PHE A 313
ILE A 321
LEU A 326
LEU A 333
MET A 345
VAL A 349
MET A 365
 None
 0.67A 1dtlA-3u0kA:
14.5		 1dtlA-3u0kA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0k RCAMP

(Entacmaea
quadricolor) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		7 PHE A 313
ILE A 321
LEU A 326
MET A 330
MET A 345
VAL A 349
MET A 365
 None
 0.76A 1dtlA-3u0kA:
14.5		 1dtlA-3u0kA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0k RCAMP

(Entacmaea
quadricolor) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		6 PHE A 386
ILE A 394
LEU A 399
MET A 403
LEU A 406
MET A 418
 None
 0.68A 1dtlA-3u0kA:
14.5		 1dtlA-3u0kA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a4z ANTIVIRAL HELICASE
SKI2

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF08148
(DSHCT)
PF13234
(rRNA_proc-arch) 		5 LEU A1171
MET A1212
VAL A1215
LEU A1129
LEU A1132
 None
 1.04A 1dtlA-4a4zA:
undetectable		 1dtlA-4a4zA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4buj ANTIVIRAL HELICASE
SKI2

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF08148
(DSHCT) 		5 LEU A1171
MET A1212
VAL A1215
LEU A1129
LEU A1132
 None
 1.02A 1dtlA-4bujA:
undetectable		 1dtlA-4bujA:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190

(Saccharomyces
cerevisiae) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		5 PHE A1570
ILE A1575
LEU A1019
LEU A1027
LEU A1023
 None
 1.05A 1dtlA-4c3hA:
undetectable		 1dtlA-4c3hA:
7.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eog PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pyrococcus
furiosus) 		PF09455
(Cas_DxTHG) 		5 PHE A 341
ILE A 347
LEU A 344
LEU A 190
LEU A 310
 None
 0.97A 1dtlA-4eogA:
undetectable		 1dtlA-4eogA:
16.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gow CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 ILE D 100
LEU D 105
MET D 109
LEU D 112
MET D 124
MET D 144
 ILE  D 100 ( 0.7A)
LEU  D 105 ( 0.6A)
MET  D 109 ( 0.0A)
LEU  D 112 ( 0.6A)
MET  D 124 ( 0.0A)
MET  D 144 ( 0.0A)
 0.96A 1dtlA-4gowD:
12.2		 1dtlA-4gowD:
53.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gow CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 ILE D 100
LEU D 105
MET D 109
LEU D 112
MET D 124
MET D 145
 ILE  D 100 ( 0.7A)
LEU  D 105 ( 0.6A)
MET  D 109 ( 0.0A)
LEU  D 112 ( 0.6A)
MET  D 124 ( 0.0A)
MET  D 145 ( 0.0A)
 1.33A 1dtlA-4gowD:
12.2		 1dtlA-4gowD:
53.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gow CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 ILE D 100
LEU D 105
MET D 109
LEU D 112
MET D 145
LEU D  18
 ILE  D 100 ( 0.7A)
LEU  D 105 ( 0.6A)
MET  D 109 ( 0.0A)
LEU  D 112 ( 0.6A)
MET  D 145 ( 0.0A)
LEU  D  18 ( 0.6A)
 1.35A 1dtlA-4gowD:
12.2		 1dtlA-4gowD:
53.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gow CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		8 PHE D  19
ILE D  27
LEU D  32
MET D  36
LEU D  39
MET D  51
VAL D  55
MET D  71
 PHE  D  19 ( 1.3A)
ILE  D  27 ( 0.7A)
LEU  D  32 ( 0.6A)
MET  D  36 ( 0.0A)
LEU  D  39 ( 0.5A)
MET  D  51 ( 0.0A)
VAL  D  55 ( 0.6A)
MET  D  71 ( 0.0A)
 0.74A 1dtlA-4gowD:
12.2		 1dtlA-4gowD:
53.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gow CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 PHE D  92
ILE D 100
LEU D 105
LEU D 112
MET D 124
MET D 144
 PHE  D  92 ( 1.3A)
ILE  D 100 ( 0.7A)
LEU  D 105 ( 0.6A)
LEU  D 112 ( 0.6A)
MET  D 124 ( 0.0A)
MET  D 144 ( 0.0A)
 0.79A 1dtlA-4gowD:
12.2		 1dtlA-4gowD:
53.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gow CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 PHE D  92
ILE D 100
LEU D 105
LEU D 112
MET D 124
MET D 145
 PHE  D  92 ( 1.3A)
ILE  D 100 ( 0.7A)
LEU  D 105 ( 0.6A)
LEU  D 112 ( 0.6A)
MET  D 124 ( 0.0A)
MET  D 145 ( 0.0A)
 1.26A 1dtlA-4gowD:
12.2		 1dtlA-4gowD:
53.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gow CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		6 PHE D  92
ILE D 100
LEU D 105
LEU D 112
MET D 145
LEU D  18
 PHE  D  92 ( 1.3A)
ILE  D 100 ( 0.7A)
LEU  D 105 ( 0.6A)
LEU  D 112 ( 0.6A)
MET  D 145 ( 0.0A)
LEU  D  18 ( 0.6A)
 1.29A 1dtlA-4gowD:
12.2		 1dtlA-4gowD:
53.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gps KLLA0E02245P

(Kluyveromyces
lactis) 		no annotation 6 PHE A 361
ILE A 360
LEU A 300
VAL A 382
MET A 182
LEU A 140
 None
 1.23A 1dtlA-4gpsA:
undetectable		 1dtlA-4gpsA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hka TRYPTOPHAN
2,3-DIOXYGENASE

(Drosophila
melanogaster) 		PF03301
(Trp_dioxygenase) 		5 PHE A  75
ILE A  78
LEU A  99
LEU A 106
VAL A 189
 None
 0.94A 1dtlA-4hkaA:
undetectable		 1dtlA-4hkaA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i2y RGECO1

(Discosoma sp.;
Gallus gallus;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		8 PHE A 322
ILE A 330
LEU A 335
MET A 339
LEU A 342
MET A 354
VAL A 358
MET A 374
 None
 0.56A 1dtlA-4i2yA:
14.4		 1dtlA-4i2yA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i2y RGECO1

(Discosoma sp.;
Gallus gallus;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		6 PHE A 395
ILE A 403
LEU A 408
MET A 412
LEU A 415
MET A 427
 None
 0.64A 1dtlA-4i2yA:
14.4		 1dtlA-4i2yA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jw1 EFFECTOR PROTEIN B

(Legionella
pneumophila) 		no annotation 5 PHE A 144
LEU A 148
LEU A 301
LEU A 241
LEU A 237
 None
 0.97A 1dtlA-4jw1A:
undetectable		 1dtlA-4jw1A:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jwq CALCIUM-DEPENDENT
PROTEIN KINASE

(Plasmodium
berghei) 		PF13499
(EF-hand_7) 		5 ILE A 145
LEU A 150
MET A 174
VAL A 178
MET A 194
 None
 0.72A 1dtlA-4jwqA:
10.4		 1dtlA-4jwqA:
27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mvf CALCIUM-DEPENDENT
PROTEIN KINASE 2

(Plasmodium
falciparum) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		5 PHE A 454
ILE A 462
LEU A  60
VAL A 492
MET A 508
 None
 1.03A 1dtlA-4mvfA:
9.2		 1dtlA-4mvfA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mvf CALCIUM-DEPENDENT
PROTEIN KINASE 2

(Plasmodium
falciparum) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		5 PHE A 454
ILE A 462
LEU A 467
VAL A 492
MET A 508
 None
 0.74A 1dtlA-4mvfA:
9.2		 1dtlA-4mvfA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oy4 CHIMERA PROTEIN OF
CALMODULIN, GPF-LIKE
PROTEIN EOSFP, AND
MYOSIN LIGHT CHAIN
KINASE

(Gallus gallus;
Lobophyllia
hemprichii;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		5 ILE A  62
LEU A  31
MET A  35
LEU A  38
MET A  50
 None
 0.74A 1dtlA-4oy4A:
2.7		 1dtlA-4oy4A:
26.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oy4 CHIMERA PROTEIN OF
CALMODULIN, GPF-LIKE
PROTEIN EOSFP, AND
MYOSIN LIGHT CHAIN
KINASE

(Gallus gallus;
Lobophyllia
hemprichii;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		5 LEU A  31
MET A  35
LEU A  38
MET A  50
VAL A  54
 None
 0.58A 1dtlA-4oy4A:
2.7		 1dtlA-4oy4A:
26.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4q57 CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		7 PHE A  19
ILE A  27
LEU A  32
LEU A  39
MET A  51
VAL A  55
MET A  71
 None
 0.62A 1dtlA-4q57A:
11.7		 1dtlA-4q57A:
42.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4q57 CALMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		7 PHE A  19
ILE A  27
LEU A  32
MET A  36
MET A  51
VAL A  55
MET A  71
 None
 0.66A 1dtlA-4q57A:
11.7		 1dtlA-4q57A:
42.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5coc IMMUNOGLOBULIN
G-BINDING PROTEIN
A,CALMODULIN

(Homo sapiens;
Staphylococcus
aureus) 		PF02216
(B)
PF13499
(EF-hand_7) 		8 PHE A1020
ILE A1028
LEU A1033
MET A1037
LEU A1040
MET A1052
VAL A1056
MET A1072
 None
 0.55A 1dtlA-5cocA:
12.6		 1dtlA-5cocA:
40.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5d43 CENTRIN-1

(Mus musculus) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		5 PHE A 113
ILE A 121
LEU A 126
LEU A 133
MET A 145
 None
 0.84A 1dtlA-5d43A:
11.8		 1dtlA-5d43A:
37.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dt9 ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE

(Vibrio cholerae) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
PF11890
(DUF3410) 		5 ILE A 145
LEU A 307
VAL A 121
MET A 111
GLU A 314
 None
 0.76A 1dtlA-5dt9A:
undetectable		 1dtlA-5dt9A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gne LEUCINE
AMINOPEPTIDASE

(Legionella
pneumophila) 		PF04389
(Peptidase_M28) 		5 ILE A 252
MET A 285
MET A 237
VAL A 241
LEU A 319
 None
 0.90A 1dtlA-5gneA:
undetectable		 1dtlA-5gneA:
20.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5h7d ZPA963,CALMODULIN

(Caenorhabditis
elegans;
synthetic
construct) 		PF02216
(B)
PF13499
(EF-hand_7) 		5 PHE E 164
ILE E 172
LEU E 177
MET E 181
LEU E 184
 None
 0.77A 1dtlA-5h7dE:
8.3		 1dtlA-5h7dE:
40.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5h7d ZPA963,CALMODULIN

(Caenorhabditis
elegans;
synthetic
construct) 		PF02216
(B)
PF13499
(EF-hand_7) 		5 PHE E 164
ILE E 172
MET E 181
LEU E 184
MET E 196
 None
 0.81A 1dtlA-5h7dE:
8.3		 1dtlA-5h7dE:
40.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5h7d ZPA963,CALMODULIN

(Caenorhabditis
elegans;
synthetic
construct) 		PF02216
(B)
PF13499
(EF-hand_7) 		5 PHE E 164
MET E 181
LEU E 184
MET E 196
VAL E 200
 None
 0.88A 1dtlA-5h7dE:
8.3		 1dtlA-5h7dE:
40.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i2q EF-HAND
DOMAIN-CONTAINING
PROTEIN D2

(Homo sapiens) 		PF13405
(EF-hand_6) 		5 LEU A 117
MET A 121
LEU A 124
MET A 136
VAL A 140
 None
 0.77A 1dtlA-5i2qA:
11.0		 1dtlA-5i2qA:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ktk POLYKETIDE SYNTHASE
PKSJ

(Bacillus
subtilis) 		PF08659
(KR) 		5 PHE A 366
ILE A 406
LEU A 368
MET A 393
LEU A 295
 None
None
None
None
NDP  A 601 ( 4.8A)
 1.05A 1dtlA-5ktkA:
undetectable		 1dtlA-5ktkA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lfn CHONDROADHERIN

(Homo sapiens) 		PF00560
(LRR_1)
PF01462
(LRRNT)
PF13855
(LRR_8) 		6 ILE A  46
LEU A  58
LEU A 106
VAL A  49
MET A  74
LEU A 104
 None
 1.23A 1dtlA-5lfnA:
undetectable		 1dtlA-5lfnA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5owo CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1

(Homo sapiens) 		no annotation 5 ILE A 125
LEU A  30
LEU A  37
MET A  65
LEU A 116
 None
 1.04A 1dtlA-5owoA:
undetectable		 1dtlA-5owoA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ukg K-GECO

(Entacmaea
quadricolor) 		no annotation 7 ILE A 292
LEU A 297
MET A 301
LEU A 304
MET A 316
VAL A 320
LEU A  15
 None
 1.17A 1dtlA-5ukgA:
12.8		 1dtlA-5ukgA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ukg K-GECO

(Entacmaea
quadricolor) 		no annotation 7 LEU A 297
MET A 301
LEU A 304
MET A 316
VAL A 320
MET A 336
LEU A  15
 None
 1.41A 1dtlA-5ukgA:
12.8		 1dtlA-5ukgA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ukg K-GECO

(Entacmaea
quadricolor) 		no annotation 7 PHE A 284
ILE A 292
LEU A 297
MET A 301
LEU A 304
MET A 316
VAL A 320
 None
 0.76A 1dtlA-5ukgA:
12.8		 1dtlA-5ukgA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ukg K-GECO

(Entacmaea
quadricolor) 		no annotation 7 PHE A 284
LEU A 297
MET A 301
LEU A 304
MET A 316
VAL A 320
MET A 336
 None
 0.92A 1dtlA-5ukgA:
12.8		 1dtlA-5ukgA:
16.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5w88 TROPONIN C, TROPONIN
I

(Homo sapiens) 		PF00992
(Troponin)
PF13833
(EF-hand_8) 		7 PHE A  27
ILE A  36
LEU A  41
MET A  45
LEU A  48
MET A  60
VAL A  64
 9XG  A 201 (-3.8A)
9XG  A 201 ( 3.3A)
9XG  A 201 (-3.9A)
9XG  A 201 (-2.4A)
9XG  A 201 ( 4.8A)
9XG  A 201 (-4.0A)
None
 0.78A 1dtlA-5w88A:
10.7		 1dtlA-5w88A:
65.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ez8 HUNTINGTIN

(Homo sapiens) 		no annotation 5 ILE A 106
LEU A 121
LEU A 166
LEU A 192
LEU A 189
 None
 1.01A 1dtlA-6ez8A:
undetectable		 1dtlA-6ez8A:
11.76