SIMILAR PATTERNS OF AMINO ACIDS FOR 1DSD_C_DVAC2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a5f MONOCLONAL
ANTI-E-SELECTIN 7A9
ANTIBODY (HEAVY
CHAIN)


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 124
PRO H 154
THR H 123
PRO H 125
None
1.35A 1dsdC-1a5fH:
undetectable
1dsdC-1a5fH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cl7 PROTEIN (IGG1
ANTIBODY 1696
(VARIABLE HEAVY
CHAIN))
PROTEIN (IGG1
ANTIBODY 1696
(CONSTANT HEAVY
CHAIN))


(Mus musculus;
Mus musculus)
PF07686
(V-set)
PF07654
(C1-set)
4 THR H 116
PRO H 118
THR H 117
PRO I 154
None
1.35A 1dsdC-1cl7H:
undetectable
1dsdC-1cl7H:
7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cl7 PROTEIN (IGG1
ANTIBODY 1696
(VARIABLE HEAVY
CHAIN))
PROTEIN (IGG1
ANTIBODY 1696
(CONSTANT HEAVY
CHAIN))


(Mus musculus;
Mus musculus)
PF07686
(V-set)
PF07654
(C1-set)
4 THR H 117
PRO I 154
THR H 116
PRO H 118
None
1.25A 1dsdC-1cl7H:
undetectable
1dsdC-1cl7H:
7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ct8 7C8 FAB FRAGMENT
LONG CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR B 116
PRO B 118
THR B 117
PRO B 147
None
1.32A 1dsdC-1ct8B:
undetectable
1dsdC-1ct8B:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eo8 ANTIBODY (HEAVY
CHAIN)


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 117
PRO H 147
THR H 116
PRO H 118
None
1.30A 1dsdC-1eo8H:
undetectable
1dsdC-1eo8H:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f3d CATALYTIC ANTIBODY
4B2


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 125
PRO H 155
THR H 124
PRO H 126
None
1.34A 1dsdC-1f3dH:
undetectable
1dsdC-1f3dH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ghf ANTI-ANTI-IDIOTYPE
GH1002 FAB FRAGMENT


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 118
PRO H 120
THR H 119
PRO H 149
None
1.31A 1dsdC-1ghfH:
undetectable
1dsdC-1ghfH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ghf ANTI-ANTI-IDIOTYPE
GH1002 FAB FRAGMENT


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 119
PRO H 149
THR H 118
PRO H 120
None
1.25A 1dsdC-1ghfH:
undetectable
1dsdC-1ghfH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1il1 MONOCLONAL ANTIBODY
G3-519 (HEAVY CHAIN)


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR A 124
PRO A 126
THR A 125
PRO A 155
None
1.35A 1dsdC-1il1A:
undetectable
1dsdC-1il1A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1il1 MONOCLONAL ANTIBODY
G3-519 (HEAVY CHAIN)


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR A 125
PRO A 155
THR A 124
PRO A 126
None
1.32A 1dsdC-1il1A:
undetectable
1dsdC-1il1A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kwg BETA-GALACTOSIDASE

(Thermus
thermophilus)
PF02449
(Glyco_hydro_42)
PF08532
(Glyco_hydro_42M)
PF08533
(Glyco_hydro_42C)
4 THR A  75
PRO A  72
THR A  73
PRO A  76
None
1.32A 1dsdC-1kwgA:
undetectable
1dsdC-1kwgA:
2.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ngq N1G9 (IGG1-LAMBDA)

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 123
PRO H 125
THR H 124
PRO H 154
None
1.23A 1dsdC-1ngqH:
undetectable
1dsdC-1ngqH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ngq N1G9 (IGG1-LAMBDA)

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 124
PRO H 154
THR H 123
PRO H 125
None
1.16A 1dsdC-1ngqH:
undetectable
1dsdC-1ngqH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q0y FAB 9B1, HEAVY CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 116
PRO H 118
THR H 117
PRO H 149
None
1.32A 1dsdC-1q0yH:
undetectable
1dsdC-1q0yH:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q0y FAB 9B1, HEAVY CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 117
PRO H 149
THR H 116
PRO H 118
None
1.27A 1dsdC-1q0yH:
undetectable
1dsdC-1q0yH:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qfu PROTEIN
(IMMUNOGLOBULIN
IGG1-KAPPA ANTIBODY
(HEAVY CHAIN))


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 117
PRO H 147
THR H 116
PRO H 118
None
1.31A 1dsdC-1qfuH:
undetectable
1dsdC-1qfuH:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgc PROTEIN
(IMMUNOGLOBULIN
HEAVY CHAIN)


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR A 123
PRO A 125
THR A 124
PRO A 154
None
1.25A 1dsdC-1qgcA:
undetectable
1dsdC-1qgcA:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgc PROTEIN
(IMMUNOGLOBULIN
HEAVY CHAIN)


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR A 124
PRO A 154
THR A 123
PRO A 125
None
1.18A 1dsdC-1qgcA:
undetectable
1dsdC-1qgcA:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rfd FAB M82G2, HEAVY
CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 117
PRO H 149
THR H 116
PRO H 118
None
1.35A 1dsdC-1rfdH:
undetectable
1dsdC-1rfdH:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rih HEAVY CHAIN OF
ANTIBODY 14F7


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 117
PRO H 147
THR H 116
PRO H 118
None
1.32A 1dsdC-1rihH:
undetectable
1dsdC-1rihH:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rur IMMUNOGLOBULIN 13G5,
HEAVY CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 117
PRO H 149
THR H 116
PRO H 118
None
1.35A 1dsdC-1rurH:
undetectable
1dsdC-1rurH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a77 IMMUNOGLOBULIN HEAVY
CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 127
PRO H 157
THR H 126
PRO H 128
None
1.33A 1dsdC-2a77H:
undetectable
1dsdC-2a77H:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ck0 PROTEIN
(IMMUNOGLOBULIN
HEAVY CHAIN)


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 121
PRO H 151
THR H 120
PRO H 122
None
1.30A 1dsdC-2ck0H:
undetectable
1dsdC-2ck0H:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fd6 H CHAIN OF FAB OF
ATN-615 ANTI-UPAR
ANTIBODY


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 116
PRO H 118
THR H 117
PRO H 142
None
1.34A 1dsdC-2fd6H:
undetectable
1dsdC-2fd6H:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fd6 H CHAIN OF FAB OF
ATN-615 ANTI-UPAR
ANTIBODY


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 117
PRO H 142
THR H 116
PRO H 118
None
1.27A 1dsdC-2fd6H:
undetectable
1dsdC-2fd6H:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gjz CATALYTIC
ELIMINATION ANTIBODY
13G5 HEAVY CHAIN


(Mus musculus)
no annotation 4 THR H 116
PRO H 118
THR H 117
PRO H 149
None
1.35A 1dsdC-2gjzH:
undetectable
1dsdC-2gjzH:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gjz CATALYTIC
ELIMINATION ANTIBODY
13G5 HEAVY CHAIN


(Mus musculus)
no annotation 4 THR H 117
PRO H 149
THR H 116
PRO H 118
None
1.29A 1dsdC-2gjzH:
undetectable
1dsdC-2gjzH:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jel JEL42 FAB FRAGMENT

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 116
PRO H 118
THR H 117
PRO H 149
None
1.34A 1dsdC-2jelH:
undetectable
1dsdC-2jelH:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jel JEL42 FAB FRAGMENT

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 117
PRO H 149
THR H 116
PRO H 118
None
1.27A 1dsdC-2jelH:
undetectable
1dsdC-2jelH:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ok0 FAB ED10 HEAVY CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 117
PRO H 149
THR H 116
PRO H 118
None
1.33A 1dsdC-2ok0H:
undetectable
1dsdC-2ok0H:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2op4 MURINE ANTIBODY FAB
RS2-1G9 IGG1 HEAVY
CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 116
PRO H 118
THR H 117
PRO H 149
None
1.34A 1dsdC-2op4H:
undetectable
1dsdC-2op4H:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2op4 MURINE ANTIBODY FAB
RS2-1G9 IGG1 HEAVY
CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 117
PRO H 149
THR H 116
PRO H 118
None
1.25A 1dsdC-2op4H:
undetectable
1dsdC-2op4H:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oz4 FAB FRAGMENT, HEAVY
CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 118
PRO H 148
THR H 117
PRO H 119
None
1.27A 1dsdC-2oz4H:
undetectable
1dsdC-2oz4H:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q09 IMIDAZOLONEPROPIONAS
E


(unidentified)
PF01979
(Amidohydro_1)
4 THR A  16
PRO A  66
THR A  65
PRO A  14
None
1.31A 1dsdC-2q09A:
undetectable
1dsdC-2q09A:
3.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q8b 1F9 HEAVY CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 115
PRO H 117
THR H 116
PRO H 146
None
1.25A 1dsdC-2q8bH:
undetectable
1dsdC-2q8bH:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q8b 1F9 HEAVY CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 116
PRO H 146
THR H 115
PRO H 117
None
1.21A 1dsdC-2q8bH:
undetectable
1dsdC-2q8bH:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r1y FAB, ANTIBODY
FRAGMENT (IGG1K),
HEAVY CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR B 115
PRO B 145
THR B 114
PRO B 116
None
1.29A 1dsdC-2r1yB:
undetectable
1dsdC-2r1yB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w9d ICSM 18-ANTI-PRP
THERAPEUTIC FAB
HEAVY CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 120
PRO H 149
THR H 119
PRO H 121
None
1.31A 1dsdC-2w9dH:
undetectable
1dsdC-2w9dH:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ymx FAB ANTIBODY HEAVY
CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 128
PRO H 158
THR H 127
PRO H 129
None
1.31A 1dsdC-2ymxH:
undetectable
1dsdC-2ymxH:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bqu 3H6 FAB HEAVY CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR D 126
PRO D 158
THR D 125
PRO D 127
None
1.35A 1dsdC-3bquD:
undetectable
1dsdC-3bquD:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d9a HEAVY CHAIN OF
HYHEL10 ANTIBODY
FRAGMENT (FAB)


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 417
PRO H 447
THR H 416
PRO H 418
THR  H 417 ( 0.8A)
PRO  H 447 ( 1.1A)
THR  H 416 ( 0.8A)
PRO  H 418 ( 1.1A)
1.33A 1dsdC-3d9aH:
undetectable
1dsdC-3d9aH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i75 ANTIBODY LIGHT CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR B 128
PRO B 130
THR B 129
PRO B 158
SO4  B 228 (-3.7A)
None
None
None
1.35A 1dsdC-3i75B:
undetectable
1dsdC-3i75B:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i75 ANTIBODY LIGHT CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR B 129
PRO B 158
THR B 128
PRO B 130
None
None
SO4  B 228 (-3.7A)
None
1.29A 1dsdC-3i75B:
undetectable
1dsdC-3i75B:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3liz 4C3 MONOCLONAL
ANTIBODY HEAVY CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 123
PRO H 153
THR H 122
PRO H 124
None
1.34A 1dsdC-3lizH:
undetectable
1dsdC-3lizH:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR A 117
PRO A 147
THR A 116
PRO A 118
None
1.35A 1dsdC-3nz8A:
undetectable
1dsdC-3nz8A:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ra7 FAB FRAGMENT, HEAVY
CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 128
PRO H 130
THR H 129
PRO H 159
None
1.28A 1dsdC-3ra7H:
undetectable
1dsdC-3ra7H:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ra7 FAB FRAGMENT, HEAVY
CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 129
PRO H 159
THR H 128
PRO H 130
None
1.21A 1dsdC-3ra7H:
undetectable
1dsdC-3ra7H:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ria MOUSE MONOCLONAL FAB
FRAGMENT, HEAVY
CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR F 125
PRO F 127
THR F 126
PRO F 156
None
1.27A 1dsdC-3riaF:
undetectable
1dsdC-3riaF:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ria MOUSE MONOCLONAL FAB
FRAGMENT, HEAVY
CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR F 126
PRO F 156
THR F 125
PRO F 127
None
1.20A 1dsdC-3riaF:
undetectable
1dsdC-3riaF:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sge HEAVY CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 119
PRO H 149
THR H 118
PRO H 120
None
1.29A 1dsdC-3sgeH:
undetectable
1dsdC-3sgeH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uyr ANTIBODY FAB HEAVY
CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 121
PRO H 151
THR H 120
PRO H 122
None
1.34A 1dsdC-3uyrH:
undetectable
1dsdC-3uyrH:
6.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v6o MONOCLONAL ANTIBODY
9F8 FAB FRAGMENT
HEAVY CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR C 122
PRO C 124
THR C 123
PRO C 153
None
1.35A 1dsdC-3v6oC:
undetectable
1dsdC-3v6oC:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v6o MONOCLONAL ANTIBODY
9F8 FAB FRAGMENT
HEAVY CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR C 123
PRO C 153
THR C 122
PRO C 124
None
1.29A 1dsdC-3v6oC:
undetectable
1dsdC-3v6oC:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v6z FAB E6 HEAVY CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR A 127
PRO A 157
THR A 126
PRO A 128
None
1.34A 1dsdC-3v6zA:
undetectable
1dsdC-3v6zA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dw2 FAB FRAGMENT OF
PRO-UPA ANTIBODY
MAB-112


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 116
PRO H 118
THR H 117
PRO H 141
None
1.35A 1dsdC-4dw2H:
undetectable
1dsdC-4dw2H:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dw2 FAB FRAGMENT OF
PRO-UPA ANTIBODY
MAB-112


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 117
PRO H 141
THR H 116
PRO H 118
None
1.21A 1dsdC-4dw2H:
undetectable
1dsdC-4dw2H:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4edx HEAVY CHAIN OF FAB
OF MURINE ANTI-NGF


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR B 116
PRO B 118
THR B 117
PRO B 149
None
1.33A 1dsdC-4edxB:
undetectable
1dsdC-4edxB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ij3 HEAVY CHAIN OF FAB
FRAGMENT


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR C 121
PRO C 123
THR C 122
PRO C 152
None
1.33A 1dsdC-4ij3C:
undetectable
1dsdC-4ij3C:
4.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ij3 HEAVY CHAIN OF FAB
FRAGMENT


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR C 122
PRO C 152
THR C 121
PRO C 123
None
1.28A 1dsdC-4ij3C:
undetectable
1dsdC-4ij3C:
4.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 116
PRO H 118
THR H 117
PRO H 147
None
1.10A 1dsdC-4k24H:
undetectable
1dsdC-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 117
PRO H 147
THR H 116
PRO H 118
None
1.05A 1dsdC-4k24H:
undetectable
1dsdC-4k24H:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l37 SILKWORM STORAGE
PROTEIN


(Bombyx mori)
PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C)
4 THR A   8
PRO A  10
THR A   9
PRO A 577
None
1.21A 1dsdC-4l37A:
undetectable
1dsdC-4l37A:
1.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lvn NIMP.M7 FAB HEAVY
CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR C 124
PRO C 154
THR C 123
PRO C 125
None
1.28A 1dsdC-4lvnC:
undetectable
1dsdC-4lvnC:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mhh H5M9 ANTIBODY, HEAVY
CHAIN (IGG1)


(Mus musculus)
no annotation 4 THR H 116
PRO H 118
THR H 117
PRO H 149
None
1.29A 1dsdC-4mhhH:
undetectable
1dsdC-4mhhH:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mhh H5M9 ANTIBODY, HEAVY
CHAIN (IGG1)


(Mus musculus)
no annotation 4 THR H 117
PRO H 149
THR H 116
PRO H 118
None
1.27A 1dsdC-4mhhH:
undetectable
1dsdC-4mhhH:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4odw A6 FAB (IGG2B) HEAVY
CHAIN


(Mus musculus)
no annotation 4 THR H 117
PRO H 146
THR H 116
PRO H 118
None
1.34A 1dsdC-4odwH:
undetectable
1dsdC-4odwH:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4onf 3D6 FAB ANTIBODY
HEAVY CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 122
PRO H 124
THR H 123
PRO H 153
None
1.33A 1dsdC-4onfH:
undetectable
1dsdC-4onfH:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4onf 3D6 FAB ANTIBODY
HEAVY CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 123
PRO H 153
THR H 122
PRO H 124
None
1.29A 1dsdC-4onfH:
undetectable
1dsdC-4onfH:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p3c HEAVY CHAIN FAB
FRAGMENT OF ANTIBODY
LEM-2/15


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 122
PRO H 152
THR H 121
PRO H 123
None
1.34A 1dsdC-4p3cH:
undetectable
1dsdC-4p3cH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6i HEAVY CHAIN OF
MURINE 2D5 FAB


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR B 116
PRO B 118
THR B 117
PRO B 147
None
1.35A 1dsdC-4q6iB:
undetectable
1dsdC-4q6iB:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6i HEAVY CHAIN OF
MURINE 2D5 FAB


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR B 117
PRO B 147
THR B 116
PRO B 118
None
1.28A 1dsdC-4q6iB:
undetectable
1dsdC-4q6iB:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qex ANTIBODY HEAVY CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 116
PRO H 146
THR H 115
PRO H 117
None
1.30A 1dsdC-4qexH:
undetectable
1dsdC-4qexH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qti ANTI-UPAR ANTIBODY,
HEAVY CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 126
PRO H 156
THR H 125
PRO H 127
None
1.35A 1dsdC-4qtiH:
undetectable
1dsdC-4qtiH:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgn 14G8 HEAVY CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR B 124
PRO B 154
THR B 123
PRO B 125
None
1.33A 1dsdC-4rgnB:
undetectable
1dsdC-4rgnB:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uom FAB FRAGMENT HEAVY
CHAIN


(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 119
PRO H 121
THR H 120
PRO H 150
None
1.34A 1dsdC-4uomH:
undetectable
1dsdC-4uomH:
7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uom FAB FRAGMENT HEAVY
CHAIN


(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 120
PRO H 150
THR H 119
PRO H 121
None
1.27A 1dsdC-4uomH:
undetectable
1dsdC-4uomH:
7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxb FAB 83-7 HEAVY CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR A 122
PRO A 152
THR A 121
PRO A 123
None
1.32A 1dsdC-4zxbA:
undetectable
1dsdC-4zxbA:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b6f ANTI-LEUKOTRIENE C4
MONOCLONAL ANTIBODY
IMMUNOGLOBULIN
GAMMA1 HEAVY CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR B 141
PRO B 171
THR B 140
PRO B 142
None
1.31A 1dsdC-5b6fB:
undetectable
1dsdC-5b6fB:
3.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c0n FAB CA33 HEAVY CHAIN

(Oryctolagus
cuniculus)
no annotation 4 THR H 124
PRO H 154
THR H 123
PRO H 125
None
1.31A 1dsdC-5c0nH:
undetectable
1dsdC-5c0nH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5do2 4C2 HEAVY CHAIN

(Mus musculus)
no annotation 4 THR H 120
PRO H 150
THR H 119
PRO H 121
None
1.33A 1dsdC-5do2H:
undetectable
1dsdC-5do2H:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5foe GDP-FUCOSE PROTEIN
O-FUCOSYLTRANSFERASE
2,THROMBOSPONDIN-1


(Caenorhabditis
elegans;
Homo sapiens)
PF00090
(TSP_1)
PF10250
(O-FucT)
4 THR A 304
PRO A 303
THR A 308
PRO A 306
None
1.23A 1dsdC-5foeA:
undetectable
1dsdC-5foeA:
2.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5foe GDP-FUCOSE PROTEIN
O-FUCOSYLTRANSFERASE
2,THROMBOSPONDIN-1


(Caenorhabditis
elegans;
Homo sapiens)
PF00090
(TSP_1)
PF10250
(O-FucT)
4 THR A 308
PRO A 306
THR A 304
PRO A 303
None
1.25A 1dsdC-5foeA:
undetectable
1dsdC-5foeA:
2.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5foh POLYSACCHARIDE
MONOOXYGENASE


(Neurospora
crassa)
PF03443
(Glyco_hydro_61)
4 THR A  46
PRO A  48
THR A  47
PRO A  23
None
1.09A 1dsdC-5fohA:
undetectable
1dsdC-5fohA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5foh POLYSACCHARIDE
MONOOXYGENASE


(Neurospora
crassa)
PF03443
(Glyco_hydro_61)
4 THR A  47
PRO A  23
THR A  46
PRO A  48
None
1.15A 1dsdC-5fohA:
undetectable
1dsdC-5fohA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hdq FAB HEAVY CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 117
PRO H 147
THR H 116
PRO H 118
None
1.33A 1dsdC-5hdqH:
undetectable
1dsdC-5hdqH:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jor FAB14.22 HEAVY CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR B 116
PRO B 118
THR B 117
PRO B 147
None
1.19A 1dsdC-5jorB:
undetectable
1dsdC-5jorB:
5.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jor FAB14.22 HEAVY CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR B 117
PRO B 147
THR B 116
PRO B 118
None
1.15A 1dsdC-5jorB:
undetectable
1dsdC-5jorB:
5.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l56 PLEXIN-A1

(Mus musculus)
PF01403
(Sema)
PF01437
(PSI)
PF01833
(TIG)
4 THR A 187
PRO A 197
THR A 198
PRO A 188
None
1.33A 1dsdC-5l56A:
undetectable
1dsdC-5l56A:
1.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l56 PLEXIN-A1

(Mus musculus)
PF01403
(Sema)
PF01437
(PSI)
PF01833
(TIG)
4 THR A 198
PRO A 188
THR A 187
PRO A 197
None
1.26A 1dsdC-5l56A:
undetectable
1dsdC-5l56A:
1.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ldn ANTIBODY

(Mus musculus)
no annotation 4 THR H 120
PRO H 150
THR H 119
PRO H 121
None
1.30A 1dsdC-5ldnH:
undetectable
1dsdC-5ldnH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5myx FAB C#24 HEAVY CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR B 119
PRO B 149
THR B 118
PRO B 120
None
1.32A 1dsdC-5myxB:
undetectable
1dsdC-5myxB:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o2v NUCLEOLYSIN TIA-1
ISOFORM P40


(Homo sapiens)
PF00076
(RRM_1)
4 THR A  82
PRO A  84
THR A  83
PRO A   6
None
1.22A 1dsdC-5o2vA:
undetectable
1dsdC-5o2vA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ocy ACPA E4 FAB FRAGMENT
- HEAVY CHAIN


(Homo sapiens)
no annotation 4 THR H 124
PRO H 154
THR H 123
PRO H 125
None
1.34A 1dsdC-5ocyH:
undetectable
1dsdC-5ocyH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vlp FAB7G7 HEAVY CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 THR H 128
PRO H 158
THR H 127
PRO H 129
None
1.32A 1dsdC-5vlpH:
undetectable
1dsdC-5vlpH:
6.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vxr MAB24 VARIABLE HEAVY
CHAIN,MAB24 VARIABLE
HEAVY CHAIN


(Mus musculus)
no annotation 4 THR H 123
PRO H 153
THR H 122
PRO H 124
None
1.31A 1dsdC-5vxrH:
undetectable
1dsdC-5vxrH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xjm FABH

(Mus musculus)
no annotation 4 THR H 123
PRO H 125
THR H 124
PRO H 154
None
1.35A 1dsdC-5xjmH:
undetectable
1dsdC-5xjmH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xjm FABH

(Mus musculus)
no annotation 4 THR H 124
PRO H 154
THR H 123
PRO H 125
None
1.26A 1dsdC-5xjmH:
undetectable
1dsdC-5xjmH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aun PLA2G6, IPLA2BETA

(Cricetulus
griseus)
no annotation 4 THR A 345
PRO A 353
THR A 352
PRO A 346
None
1.32A 1dsdC-6aunA:
undetectable
1dsdC-6aunA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bpd MONOCLONAL ANTIBODY
10B12 FAB HEAVY
CHAIN


(Mus musculus)
no annotation 4 THR A 142
PRO A 172
THR A 141
PRO A 143
None
1.32A 1dsdC-6bpdA:
undetectable
1dsdC-6bpdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bzy 22D11 HEAVY CHAIN

(Mus musculus)
no annotation 4 THR H 117
PRO H 147
THR H 116
PRO H 118
None
1.34A 1dsdC-6bzyH:
undetectable
1dsdC-6bzyH:
undetectable